CN101601852A - A kind of Chinese medicine preparation for the treatment of vascular migraine - Google Patents

A kind of Chinese medicine preparation for the treatment of vascular migraine Download PDF

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Publication number
CN101601852A
CN101601852A CNA2008101149376A CN200810114937A CN101601852A CN 101601852 A CN101601852 A CN 101601852A CN A2008101149376 A CNA2008101149376 A CN A2008101149376A CN 200810114937 A CN200810114937 A CN 200810114937A CN 101601852 A CN101601852 A CN 101601852A
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weight portion
radix
chinese medicine
medicine preparation
treatment
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CNA2008101149376A
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Chinese (zh)
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何俊保
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BEIJING ZHONGTAI TIANHE SCIENCE AND TECHNOLOGY Co Ltd
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BEIJING ZHONGTAI TIANHE SCIENCE AND TECHNOLOGY Co Ltd
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Priority to CNA2008101149376A priority Critical patent/CN101601852A/en
Publication of CN101601852A publication Critical patent/CN101601852A/en
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Abstract

The invention discloses a kind of Chinese medicine preparation for the treatment of vascular migraine.It mainly is made by Radix Angelicae Sinensis, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Radix Scutellariae, Ramulus Uncariae Cum Uncis, Radix Glycyrrhizae, Rhizoma Cyperi, the Radix Paeoniae Alba, Radix Ophiopogonis, Flos Chrysanthemi, Rhizoma Zingiberis Recens, is pure Chinese medicinal preparation, has the effect of heat-clearing and toxic substances removing, removing obstruction in the collateral to relieve pain, and is better to treatment vascular migraine effect.

Description

A kind of Chinese medicine preparation for the treatment of vascular migraine
Technical field
The invention belongs to field of traditional Chinese, be specifically related to a kind of Chinese medicine preparation for the treatment of vascular migraine, and its preparation method has been done correlational study.
Technical background
Migraine is a kind of pulsatile headache of showing effect repeatedly, belongs to " rich and influential family " in numerous headache types.Before its outbreak tendencys such as flash of light, blurred vision, numb limbs and tense tendons are often arranged, the pain that one side head one is jumped appearred in approximate number minute to about 1 hour, and aggravation gradually, up to occur to feel sick, after the vomiting, sensation just has improvements in quiet, dark surrounds or the alleviation of having a headache after the sleep.Can be before headache takes place or during outbreak with nerve, moral function obstacle.Simultaneously, it is a kind of disease that can progressively worsen, and frequency of disease development is more and more higher usually.Show that according to the study the migraineur is the easier generation brain of people local damage than usual, and then cause apoplexy.Its migrainous number of times is many more, and the zone of brain damaged can be big more.
Migraine is the vascular headache of periodical attack.Its characteristics for headache in a side, with feel sick, photophobia etc.Clinical symptoms performance: tendency shows as feeling of fatigue, and emotional or spirit depressing, is of short durationly forgotten the minority hemiplegia at dizzy, tinnitus.To begin be a side frontal temporal part position in headache, heavy in gradually behind the eyeball, or a side head or full headache around the eye socket, is that pulsation has an intense pain and consistent with vein, the most serious companion's nausea and vomiting about half an hour, pale complexion, photophobia.Alleviated annual outbreak 1 time to 2 times in 2 hours-3 hours.Knowing more than the minimum two thousand years on the medical history.Migraine is a kind of very excruciating disease, and its pain scope is confined to head one side usually, but also has both sides simultaneous.The position reaches forehead or head at temples usually, and certain diversity is arranged.The number of times that takes place can take place several times in 1 year, and one month for several times or took place once in several days, and the outbreak persistent period can be at several hours or several days.
Migrainous symptom is the headache of pulsation when beginning, and is derived from the top or the back of certain a glance usually; Or also may the back side from the beginning begin outbreak, prolong then and a treating selvedge of head.It usually with feel sick, vomiting, blurred vision, extremity twinge and paralysis (sustainable 18 hours).Typical migraine has omen when taking place, comprise that vision is obscured, speaking incoherently, body void, variously feel disturbed.Also may comprise in addition and have some glittering starlight sparks or simple geometric shape to skim in the visual field.Anaphylaxis is common migraine reason.It comprises irritated food, (as: Semen Tritici aestivi, chocolate, monosodium glutamate [MsG), sulphite [be used for salad), Phenylalanine and cheese amine, nitrite [antiseptic that hot dog is contained], aspirin, sugar, citric acid, fermented foodstuff [cheese, sour buttermilk], wine etc.) environmental pollution etc.; Constipation, anxiety and pressure, shortage motion or the like all may be to cause migrainous latency, and it also can be caused by hepatic disfunction.70% migraineur is the women, and this disease has familial tendency and may be relevant with heredity usually.The chemical composition content of many patient's brains is undesired, causes cerebrovascular overdistension or contraction.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine preparation for the treatment of vascular migraine, comprises its drug regimen and preparation method.
Be achieved through the following technical solutions order of the present invention:
1, the present invention is made by the following weight proportion raw material:
Radix Angelicae Sinensis 30~85 weight portion Rhizoma Corydalis 40~100 weight portion Radixs Angelicae Dahuricae 21~60 weight portions
Radix Scutellariae 21~60 weight portion Ramulus Uncariae Cum Uncis 30~85 weight portion Radix Glycyrrhizaes 30~85 weight portions
Rhizoma Cyperi 21~60 weight portion Radix Paeoniae Albas 30~85 weight portion weight portions Radix Ophiopogonis 30~85
Flos Chrysanthemi 40~100 weight portion Rhizoma Zingiberis Recenss 21~60 weight portions
2, best each the raw material weight proportioning of prescription of the present invention is:
The Radix Angelicae Sinensis 66 weight portion Rhizoma Corydalis 88 weight portion Radixs Angelicae Dahuricae 52 weight portions
Radix Scutellariae 52 weight portion Ramulus Uncariae Cum Uncis 66 weight portion Radix Glycyrrhizaes 66 weight portions
The Rhizoma Cyperi 52 weight portion Radix Paeoniae Albas 66 weight portion weight portions Radix Ophiopogonis 66
Flos Chrysanthemi 88 weight portion Rhizoma Zingiberis Recenss 52 weight portions
3, preparation method:
(1) get Rhizoma Cyperi, the Radix Paeoniae Alba, Radix Ophiopogonis, Flos Chrysanthemi, Rhizoma Zingiberis Recens, decoct with water, collecting decoction is concentrated into into thick paste, adds the ethanol precipitate with ethanol, leave standstill, and the supernatant decompression recycling ethanol, and be condensed into extractum, standby;
(2) get 6 flavors such as all the other Radix Angelicae Sinensis, Rhizoma Corydalis, be ground into coarse powder, use ethanol percolation, collect 10~15 times of percolates, behind the decompression recycling ethanol, be condensed into extractum, standby;
(3) merge above-mentioned two kinds of extractum, be condensed into thick paste; Or, be ground into dried cream powder with the thick paste drying;
(4) add suitable adjuvant in thick paste or the dried cream powder after, mixing is granulated, drying is made into pill, powder, granule, tablet (plain sheet, Film coated tablets, enteric coated tablet, coated tablet), syrup, mixture, capsule etc. again.
The invention discloses a kind of Chinese medicine preparation for the treatment of vascular migraine.It mainly is made by Radix Angelicae Sinensis, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Radix Scutellariae, Ramulus Uncariae Cum Uncis, Radix Glycyrrhizae, Rhizoma Cyperi, the Radix Paeoniae Alba, Radix Ophiopogonis, Flos Chrysanthemi, Rhizoma Zingiberis Recens, is pure Chinese medicinal preparation, has the effect of heat-clearing and toxic substances removing, removing obstruction in the collateral to relieve pain, and is better to treatment vascular migraine effect.
The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
The specific embodiment
Embodiment 1: a kind of pill for the treatment of vascular migraine
Adopt following drug regimen:
Radix Angelicae Sinensis 66g Rhizoma Corydalis 88g Radix Angelicae Dahuricae 52g
Radix Scutellariae 52g Ramulus Uncariae Cum Uncis 66g Radix Glycyrrhizae 66g
Rhizoma Cyperi 52g Radix Paeoniae Alba 66g 66g Radix Ophiopogonis
Flos Chrysanthemi 88g Rhizoma Zingiberis Recens 52g
Its preparation method is:
(1) get Rhizoma Cyperi 52g, Radix Paeoniae Alba 66g, Radix Ophiopogonis 66g, Flos Chrysanthemi 88g, Rhizoma Zingiberis Recens 52g, decoct with water, collecting decoction is concentrated into into thick paste, adds the ethanol precipitate with ethanol, leave standstill, and the supernatant decompression recycling ethanol, and be condensed into extractum, standby;
(2) get 6 flavors such as all the other Radix Angelicae Sinensis, Rhizoma Corydalis, be ground into coarse powder, use ethanol percolation, collect 12 times of percolates, behind the decompression recycling ethanol, be condensed into extractum, standby;
(3) merge above-mentioned two kinds of extractum, be condensed into thick paste,, be ground into dried cream powder the thick paste drying;
(4) get dried cream powder and add appropriate amount of starch, mixing.Every 100g powder adds the about 110g of refined honey, makes small honey pill, promptly.
Embodiment 2: a kind of Film coated tablets for the treatment of vascular migraine
Adopt following drug regimen:
Radix Angelicae Sinensis 85g Rhizoma Corydalis 100g root of Dahurian angelica 60g
Radix Scutellariae 60g Ramulus Uncariae Cum Uncis 85g Radix Glycyrrhizae 85g
Rhizoma Cyperi 60g Radix Paeoniae Alba 85g 85g Radix Ophiopogonis
Flos Chrysanthemi 100 Rhizoma Zingiberis Recens 60g
Its preparation method is:
(1) get Rhizoma Cyperi 60g, Radix Paeoniae Alba 85g, Radix Ophiopogonis 85g, Flos Chrysanthemi 100g, Rhizoma Zingiberis Recens 60g, decoct with water, collecting decoction is concentrated into into thick paste, adds the ethanol precipitate with ethanol, leave standstill, and the supernatant decompression recycling ethanol, and be condensed into extractum, standby;
(2) get 6 flavors such as all the other Radix Angelicae Sinensis, Rhizoma Corydalis, be ground into coarse powder, use ethanol percolation, collect 15 times of percolates, behind the decompression recycling ethanol, be condensed into extractum, standby;
(3) merge above-mentioned two kinds of extractum, be condensed into thick paste;
(4) after thick paste added suitable adjuvant, mixing was granulated, drying, and tabletting, the bag film-coat, promptly.
Embodiment 3: a kind of capsule for the treatment of vascular migraine
Adopt following drug regimen:
Radix Angelicae Sinensis 30g Rhizoma Corydalis 40g Radix Angelicae Dahuricae 21g
Radix Scutellariae 21g Ramulus Uncariae Cum Uncis 30g Radix Glycyrrhizae 30g
Rhizoma Cyperi 21g Radix Paeoniae Alba 30g 30g Radix Ophiopogonis
Flos Chrysanthemi 40g Rhizoma Zingiberis Recens 21g
Its preparation method is:
(1) get Rhizoma Cyperi 21g, Radix Paeoniae Alba 30g, Radix Ophiopogonis 30g, Flos Chrysanthemi 40g, Rhizoma Zingiberis Recens 21g, decoct with water, collecting decoction is concentrated into into thick paste, adds the ethanol precipitate with ethanol, leave standstill, and the supernatant decompression recycling ethanol, and be condensed into extractum, standby;
(2) get 6 flavors such as all the other Radix Angelicae Sinensis, Rhizoma Corydalis, be ground into coarse powder, use ethanol percolation, collect 10 times of percolates, behind the decompression recycling ethanol, be condensed into extractum, standby;
(3) merge above-mentioned two kinds of extractum, be condensed into thick paste,, be ground into dried cream powder the thick paste drying;
(4) add the about 67g of lactose in the dried cream powder, mixing is granulated, and drying is encapsulated with it, promptly gets capsule.

Claims (4)

1, a kind of Chinese medicine preparation for the treatment of vascular migraine is characterized in that this Chinese medicine preparation comprises the raw material of following weight portion unit:
Radix Angelicae Sinensis 30~85 weight portion Rhizoma Corydalis 40~100 weight portion Radixs Angelicae Dahuricae 21~60 weight portions
Radix Scutellariae 21~60 weight portion Ramulus Uncariae Cum Uncis 30~85 weight portion Radix Glycyrrhizaes 30~85 weight portions
Rhizoma Cyperi 21~60 weight portion Radix Paeoniae Albas 30~85 weight portion weight portions Radix Ophiopogonis 30~85
Flos Chrysanthemi 40~100 weight portion Rhizoma Zingiberis Recenss 21~60 weight portions
2, a kind of Chinese medicine preparation for the treatment of vascular migraine as claimed in claim 1 is characterized in that the weight proportion of its drug regimen is:
The Radix Angelicae Sinensis 66 weight portion Rhizoma Corydalis 88 weight portion Radixs Angelicae Dahuricae 52 weight portions
Radix Scutellariae 52 weight portion Ramulus Uncariae Cum Uncis 66 weight portion Radix Glycyrrhizaes 66 weight portions
The Rhizoma Cyperi 52 weight portion Radix Paeoniae Albas 66 weight portion weight portions Radix Ophiopogonis 66
Flos Chrysanthemi 88 weight portion Rhizoma Zingiberis Recenss 52 weight portions
3, as the described a kind of Chinese medicine preparation for the treatment of vascular migraine of claim 1-2, it is characterized in that the preparation method of this Chinese medicine preparation is:
(1) get Rhizoma Cyperi, the Radix Paeoniae Alba, Radix Ophiopogonis, Flos Chrysanthemi, Rhizoma Zingiberis Recens, decoct with water, collecting decoction is concentrated into into thick paste, adds the ethanol precipitate with ethanol, leave standstill, and the supernatant decompression recycling ethanol, and be condensed into extractum, standby;
(2) get 6 flavors such as all the other Radix Angelicae Sinensis, Rhizoma Corydalis, be ground into coarse powder, use ethanol percolation, collect 10~15 times of percolates, behind the decompression recycling ethanol, be condensed into extractum, standby;
(3) merge above-mentioned two kinds of extractum, be condensed into thick paste; Or, be ground into dried cream powder with the thick paste drying;
(4) add suitable adjuvant in thick paste or the dried cream powder after, mixing is granulated, drying is made into suitable Chinese medicine preparation, promptly again.
4, as the described a kind of Chinese medicine preparation for the treatment of vascular migraine of claim 1-3, it is characterized in that the Chinese medicine preparation that suits can be: pill, powder, granule, tablet (plain sheet, Film coated tablets, enteric coated tablet, coated tablet), syrup, mixture, capsule etc.
CNA2008101149376A 2008-06-13 2008-06-13 A kind of Chinese medicine preparation for the treatment of vascular migraine Pending CN101601852A (en)

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Application Number Priority Date Filing Date Title
CNA2008101149376A CN101601852A (en) 2008-06-13 2008-06-13 A kind of Chinese medicine preparation for the treatment of vascular migraine

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102727834A (en) * 2012-07-18 2012-10-17 南京中医药大学 Traditional Chinese medicine composition for treating migraine, and preparation method and application thereof
CN104740183A (en) * 2015-04-18 2015-07-01 青岛辰达生物科技有限公司 Pharmaceutical composition for treating migraine
CN105343409A (en) * 2014-08-21 2016-02-24 李新民 Formula for treating migraine
CN105641301A (en) * 2014-11-20 2016-06-08 卢赛红 Traditional Chinese medicine for treating vascular headache
CN106421294A (en) * 2016-12-06 2017-02-22 王学建 Traditional Chinese medicine composition for treating migraine

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102727834A (en) * 2012-07-18 2012-10-17 南京中医药大学 Traditional Chinese medicine composition for treating migraine, and preparation method and application thereof
CN102727834B (en) * 2012-07-18 2013-09-04 南京中医药大学 Traditional Chinese medicine composition for treating migraine, and preparation method and application thereof
CN105343409A (en) * 2014-08-21 2016-02-24 李新民 Formula for treating migraine
CN105641301A (en) * 2014-11-20 2016-06-08 卢赛红 Traditional Chinese medicine for treating vascular headache
CN104740183A (en) * 2015-04-18 2015-07-01 青岛辰达生物科技有限公司 Pharmaceutical composition for treating migraine
CN106421294A (en) * 2016-12-06 2017-02-22 王学建 Traditional Chinese medicine composition for treating migraine

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Open date: 20091216