CN1270745C

CN1270745C - Chinese kmedicine bolus for treating femoral head necrosis and its prepn process

Info

Publication number: CN1270745C
Application number: CNB031089321A
Authority: CN
Inventors: 吕守忠; 吕崇高
Original assignee: Individual
Current assignee: Individual
Priority date: 2003-04-02
Filing date: 2003-04-02
Publication date: 2006-08-23
Anticipated expiration: 2023-04-02
Also published as: CN1636578A

Abstract

The present invention discloses a traditional Chinese medicine watered pill for treating femoral head necrosis and a preparing method of a traditional Chinese medicine watered pill for treating femoral head necrosis. The watered pill is prepared by using the following 26 traditional Chinese medicines: tortoise plastron, dog bones, achyranthes roots, fleece-flower roots, eucommia barks, radix dipsaci, broomrape, Chinese angelica roots, phellodendron barks, red ginsengs, white peony roots, prepared rhizome of rehmannia, Chinese wolfberries, frankincense, myrrh, peach kernels, safflower, notoginseng, radix morindae officinalis, drynaria, corydalis tuber, leeches, astragalus roots, scorpions and earthworms. The tortoise plastron, the dog bones, the achyranthes roots, the Chinese angelica roots, the phellodendron barks, the white peony roots, the eucommia barks, the myrrh, the frankincense, the peach kernels, the corydalis tuber and the broomrape are prepared into watered pills with the particle diameter of 4 millimeters after processed, mixed with the rest traditional Chinese medicines and pulverized; the watered pills are sterilized, metered according to 8 g/packet and packaged. The traditional Chinese medicines of the watered pill preparation are convenient to purchase. The watered pill has the advantages of simple and convenient preparation, low cost, no toxic side effect, convenient administration, no decoction, no foreign odor, convenient popularization and convenient application. The cure rate of the watered pill is practically proved to be 89.3%, and the effective rate is 95%. The watered pill is suitable for various femoral head patients.

Description

A kind of Chinese medicine watered pill for the treatment of femur head necrosis and preparation method thereof

Affiliated technical field

The present invention relates to a kind of Chinese medicine watered pill for the treatment of femur head necrosis and preparation method thereof, belong to field of pharmaceutical technology.

Background technology

Femur head necrosis belongs to osteomyelitis rheumatism involving the bone category, and the cause of disease is to cause qi depression to blood stasis, liver, renal function deficient by various factors, venation is obstructed, disturbance of blood circulation, skeleton lose moisten foster, due to the bone fragility, the clinical manifestation hip pain of primary disease, dysfunction, limbs shorten, amyotrophy is a disaster disease of orthopedics department, and sickness rate and day increase, bring great misery for patient's body and mind, pose a huge burden on society.At present, known Therapeutic Method is varied, and doctor trained in Western medicine is with the boring decompression, the vascular pedicle bone grafting of living, and replacement operation of artificial femoral head, consequently operation wound is big, and late result is difficult to prediction, and what have causes lifelong deformity to the patient, and the expense height; Part Chinese traditional treatment primary disease is varied especially, does not form unified treatment rule, and that treatment means mostly is is for oral administration, external application, acupuncture-moxibustion, massage, and its curative effect can not make patient satisfaction.

Summary of the invention

In order to overcome above-mentioned deficiency, the present invention is through for many years practice and concentrate on studies, a kind of Chinese medicine watered pill for the treatment of femur head necrosis and preparation method thereof is provided, and this watered pill preparation is according to ancient, modern theory of Chinese medical science and Therapeutic Method, with at the treatment stagnation of QI-blood, deficiency of the liver and kindey is the basic rule of treatment, with promoting blood circulation to remove obstruction in the collateral, invigorating the kidney and strengthening the bones, add that smart to mend marrow be purpose, sum up instant effect of the present invention through 316 routine clinical treatment observations, short treating period, especially to early stage, mid-term patient's curative effect more sure.A kind of Chinese medicine watered pill preparation for the treatment of femur head necrosis of the present invention is made by following component, and percentage by weight is as follows:

Carapax et Plastrum Testudinis 5%-8% Os Canitis 6%-9% Radix Achyranthis Bidentatae 3%-5%

Radix Polygoni Multiflori 4%-6% Cortex Eucommiae 3%-4% Radix Dipsaci 5%-7%

Herba Cistanches 5%-6% Radix Angelicae Sinensis 4%-6% Cortex Phellodendri 2%-3%

Radix Ginseng Rubra 5%-6% Radix Paeoniae Alba 3%-4% Radix Rehmanniae Preparata 4%-6%

Fructus Lycii 3%-4% Olibanum 3%-4% Myrrha 4%-5%

Semen Persicae 3%-4% Flos Carthami 3%-5% Radix Notoginseng 3%-5%

Radix Morindae Officinalis 4%-5% Rhizoma Drynariae 5%-7% Rhizoma Corydalis 3%-4%

Hirudo 2%-3% Radix Astragali 4%-6% Scorpio 4%-5%

worm 3%-4% Pheretima 3%-4%

The preparation method of this watered pill preparation is:

Selected above-mentioned genuine Chinese medicine, clean, air-dry with clear water, following 12 kinds of Chinese medicines to be concocted respectively, its method is: the husky back of scalding of Carapax et Plastrum Testudinis is pulled airing out with quench in vinegar; Os Canitis is roasting to deoil; Radix Achyranthis Bidentatae wine is fried; Radix Angelicae Sinensis wine is washed; Cortex Phellodendri saline is fried; The little stir-fry of the Radix Paeoniae Alba; The Cortex Eucommiae is fried and is removed silk; Myrrha is put in the pot with slow fire and is fried spray rice vinegar when seeing fusing slightly to the surface, continues to fry to outer transparent optical and reveals pot; The Olibanum concocting method is identical with Myrrha; Semen Persicae removes skin and sharp little stir-fry, and Rhizoma Corydalis vinegar is fried; Herba Cistanches is cut into slices it, mixes in all putting jar airtightly with yellow wine, it is put in adds the heating of water water proof in the pot and steams to wine and be degree to the greatest extent, takes out, airing; Again with the Chinese medicine of above-mentioned all the other each components, measure respectively by the percentage by weight after air-dry after the process of preparing Chinese medicine, mix then that to pulverize be 160 order powderies, use watered pill processing technique, make diameter and be 4 millimeters the particulate watered pill, the sterilization back is pressed 8g/ and is wrapped metering packing.

The main feature of a kind of watered pill for the treatment of femur head necrosis of the present invention and preparation method thereof is: the smart marrow of mending is added in Carapax et Plastrum Testudinis, Os Canitis, Herba Cistanches, Radix Rehmanniae Preparata, Fructus Lycii, Radix Polygoni Multiflori nourishing kidney; Radix Dipsaci, Radix Achyranthis Bidentatae, the Cortex Eucommiae, Radix Morindae Officinalis, Rhizoma Drynariae tonifying liver, bone and muscle strengthening; Semen Persicae, Flos Carthami, Hirudo, worm, Pheretima, Scorpio promoting blood circulation to remove obstruction in the collateral; Rhizoma Corydalis, Olibanum, Myrrha dissipating blood stasis end osteodynia; Radix Notoginseng, prevent that the promoting blood circulation to remove obstruction in the collateral medicine too much hinders fresh blood, hemostatic analgesia again, do not stay blood stasis, play dual regulation; Stir-baked CORTEX PHELLODENDRI with salt solution is gone into the strong bone of kidney consolidating YIN; Radix Ginseng Rubra, the Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Alba benefiting qi and nourishing blood, harmonizing yingfen and weifen, strengthening vital QI to eliminate pathogenic factors, enhancing body resistance against diseases.Full side's compatibility is played promoting blood circulation to remove obstruction in the collateral altogether, mends the bone bone strengthening and adds the smart marrow of mending, and the effect of benefiting qi and nourishing blood makes femoral head recover blood vessels, absorbs sequestrum rapidly, reaches the purpose of the new bone of regeneration.

The present invention through its advantage of clinical practice is:

Compatibility is reasonable, concocts accurately, meets the pharmacopeia regulation, belong to the agent of strengthening by means of tonics, no Da Xin, big heat, the product in Great Cold are fit to various femur head necrosis patient, have no side effect, effect with promoting blood circulation to remove obstruction in the collateral, the femoral head peripheral vessels is rebuild, increased blood capillary quantity, form the circulation of side limb, play good function of promoting blood circulation to disperse blood clots to recovering blood fortune, it is intrinsic pressure to reduce femoral head, can substitute doctor trained in Western medicine and execute operations such as boring decompression, reduces patient's misery, this preparation watered pill preparation method is concisely reasonable, with low cost, need not decoct, easy to use, alleviate patient's financial burden, easily apply.

Using method of the present invention and answer points for attention: oral one day twice, each 8g one parcel, early ante cibum, respectively obey a bag after the supper, give up alcohol, 3 months is a course of treatment, after first course of treatment, check the X-ray sheet, advise doctor's increase and decrease through doctor, during the treatment, early, mid-term the patient avoid bearing a heavy burden, in order to avoid cause collapse of the femoral head, patients with terminal can be suitably, an amount of exercise, and health invigorating makes joint space broadening, favourable femoral head reconstruction plastotype, restore funcitons.

The invention has the beneficial effects as follows: added up through 318 example practices from 1996-2002: oldest 73 years old, minimum 9 years old, medical history was the longest 18 years, the shortest 11 months, belong to traumatic 66 examples, the special property sent out 242 examples, single hip 222 examples, two hip 96 examples, wherein: early stage (1,2 phase) 148 examples, mid-term (3,4) 114 examples, late periods 56 example, wherein: male's 223 examples, women's 95 examples.

Therapeutic outcome: recovery from illness performance: the hip arthralgia disappears, functional rehabilitation, the sclerotin reparation is good, activity freely, X-ray shows the joint space, femoral head is obviously repaired, the bone trabecula marshalling; Effectively performance: the hip arthralgia alleviates, and function takes a turn for the better to some extent, but still part is limited, and expansion is not seen in X-ray demonstration femur head necrosis district, and femoral head is seen fusion slightly, but makes slow progress, and still continues to take this watered pill; Invalid performance: the hip arthralgia and function limitation do not have improvement, and X-ray shows that the femoral head pathological changes still.

Therapeutic outcome

Phase is other	Patient's number	Recovery from illness		Be almost recovered		Effectively		Invalid		Percentage rate %
		Recovery from illness		Be almost recovered		Effectively		Invalid			Number	％	Number	％	Number	％	Number	％
		In early days	148	112	75.7	36	24.3	0	0		Number	％	Number	％	Number	％	Number	％	0	0	100
Mid-term	114	In early days	148	112	75.7	36	24.3	0	0	52	45.6	42	36.8	14	12.3	6	5.26	94.7	0	0	100
Mid-term	114	Late period	56	22	39.3	20	35.7	4	7.1	52	45.6	42	36.8	14	12.3	6	5.26	94.7	10	10	82.1
Add up to	318	Late period	56	22	39.3	20	35.7	4	7.1	186		98		18		16			10	10	82.1

The ÷ 318=89.3% of cure rate=(186+98)

The ÷ 318=95% of effective percentage=(186+98+18)

The specific embodiment

Now lifting most preferred embodiment is described as follows the further specific embodiment of the present invention:

Take by weighing raw material (unit: kilogram) by following proportioning

Carapax et Plastrum Testudinis 6 Os Canitis 7.5 Radix Achyranthis Bidentataes 4 Radix Polygoni Multiflori 5

The Cortex Eucommiae 3.5 Radix Dipsacis 6 Herba Cistanches 5.5 Radix Angelicae Sinensis 5

Cortex Phellodendri 2.5 Radix Ginseng Rubra 5.5 Radix Paeoniae Albas 3.5 Radix Rehmanniaes Preparata 5

Fructus Lycii 3.5 Olibanums 3.5 Myrrhas 4.5 Semen Persicaes 3.5

Flos Carthami 4 Radix Notoginseng 4 Radix Morindae Officinaliss 4.5 Rhizoma Drynariae 6

Rhizoma Corydalis 3.5 Hirudos 2.5 Radixs Astragali 5 Scorpios 4.5

worm 3.5 Pheretimas 3.5

Selected genuine 26 kinds of Chinese medicines are clean, air-dry, pull the husky back of scalding of Carapax et Plastrum Testudinis out airing with quench in vinegar then; Os Canitis is roasting to deoil; Radix Achyranthis Bidentatae wine is fried; Radix Angelicae Sinensis wine is washed; Cortex Phellodendri saline is fried; The little stir-fry of the Radix Paeoniae Alba; The Cortex Eucommiae is fried and is removed silk; Myrrha is put in the pot with slow fire and is fried spray rice vinegar when seeing fusing slightly to the surface, continues to fry to outer transparent optical and reveals pot; The Olibanum concocting method is identical with Myrrha; Semen Persicae removes skin and sharp little stir-fry; Rhizoma Corydalis vinegar is fried; To again the Chinese medicine of above-mentioned all the other each components be measured respectively by the weight after air-dry behind above-mentioned 12 kinds of Chinese medicine processing, always mix then that to pulverize be 160 order powderies, use watered pill processing technique, make diameter and be 4 millimeters the particulate watered pill, 8g/ bag, metering packing are pressed in the sterilization back.

Claims

1, a kind of Chinese medicine watered pill for the treatment of femur head necrosis is characterized in that it is the watered pill of being made by following weight percentages

Radix Polygoni Multiflori 4%-6% Cortex Eucommiae 3%-4% Radix Dipsaci 5%-7%

Herba Cistanches 5%-6% Radix Angelicae Sinensis 4%-6% Cortex Phellodendri 2%-3%

Fructus Lycii 3%-4% Olibanum 3%-4% Myrrha 4%-5%

Semen Persicae 3%-4% Flos Carthami 3%-5% Radix Notoginseng 3%-5%

Hirudo 2%-3% Radix Astragali 4%-6% Scorpio 4%-5%

Eupolyphaga seu steleophaga 3%-4% Pheretima 3%-4%.

2, a kind of preparation method for the treatment of the Chinese medicine watered pill of femur head necrosis according to claim 1, it is characterized in that 26 kinds of Chinese medicines being made the watered pill with the method for following preparation, 26 kinds of Chinese medicines in selected tunnel, clean, air-dry with clear water, then following 12 kinds of Chinese medicines are concocted, with Carapax et Plastrum Testudinis is husky scald after, pull airing out with quench in vinegar; Os Canitis is roasting to deoil; Radix Achyranthis Bidentatae wine is fried; Radix Angelicae Sinensis wine is washed; Cortex Phellodendri saline is fried; The little stir-fry of the Radix Paeoniae Alba; The Cortex Eucommiae is fried and is removed silk; Myrrha is put in the pot with slow fire and is fried spray rice vinegar when seeing fusing slightly to the surface, continues to fry to outer transparent optical and reveals pot; The Olibanum concocting method is identical with Myrrha; Semen Persicae removes skin and sharp little stir-fry; Rhizoma Corydalis vinegar is fried; Herba Cistanches is cut into slices it, mixes thoroughly in putting jar airtightly with yellow wine, it is put in adds the heating of water water proof in the kettle and steams to wine and be degree to the greatest extent, takes out, airing; With the Chinese medicine of all the other each components, measure respectively by the percentage by weight after air-dry, mixing pulverizing then is 160 order powderies, uses watered pill technological method for processing, makes the watered pill that diameter is 4 mm granules again, wraps metering packing by 8g/ after sterilizing.