CN1268320C - 协同填料组合物 - Google Patents

协同填料组合物 Download PDF

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Publication number
CN1268320C
CN1268320C CNB028185161A CN02818516A CN1268320C CN 1268320 C CN1268320 C CN 1268320C CN B028185161 A CNB028185161 A CN B028185161A CN 02818516 A CN02818516 A CN 02818516A CN 1268320 C CN1268320 C CN 1268320C
Authority
CN
China
Prior art keywords
tablet
pvp
copolymer
microcrystalline cellulose
hardness
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB028185161A
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English (en)
Chinese (zh)
Other versions
CN1556695A (zh
Inventor
A·莫罗尼
N·G·纳勒尔拉
G·杜布朗尼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISP Investments LLC
Original Assignee
ISP Investments LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISP Investments LLC filed Critical ISP Investments LLC
Publication of CN1556695A publication Critical patent/CN1556695A/zh
Application granted granted Critical
Publication of CN1268320C publication Critical patent/CN1268320C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CNB028185161A 2001-07-25 2002-05-10 协同填料组合物 Expired - Lifetime CN1268320C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/915,057 2001-07-25
US09/915,057 US6524617B1 (en) 2001-07-25 2001-07-25 Synergistic filler composition

Publications (2)

Publication Number Publication Date
CN1556695A CN1556695A (zh) 2004-12-22
CN1268320C true CN1268320C (zh) 2006-08-09

Family

ID=25435143

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028185161A Expired - Lifetime CN1268320C (zh) 2001-07-25 2002-05-10 协同填料组合物

Country Status (12)

Country Link
US (1) US6524617B1 (enExample)
EP (1) EP1416918B1 (enExample)
JP (1) JP4805537B2 (enExample)
CN (1) CN1268320C (enExample)
AT (1) ATE327738T1 (enExample)
BR (1) BRPI0211439B1 (enExample)
CA (1) CA2454449C (enExample)
DE (1) DE60211916T2 (enExample)
ES (1) ES2266502T3 (enExample)
MX (1) MXPA04000666A (enExample)
RU (1) RU2304981C2 (enExample)
WO (1) WO2003011253A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6620900B2 (en) * 2002-02-07 2003-09-16 Isp Investments Inc. Proliferous copolymer of vinyl pyrrolidone and vinyl acetate
JP4776233B2 (ja) * 2002-11-12 2011-09-21 エラン ファーマ インターナショナル，リミティド 摩損しにくくかつプルランを含む速崩壊性固形製剤
US7704528B2 (en) * 2003-05-05 2010-04-27 Isp Investments Inc. Binder composition and method for processing poorly compressible drugs into tablets of predetermined hardness and friability
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
US8168219B2 (en) * 2005-11-30 2012-05-01 Isp Investments Inc. Synergistic binder composition, method for making same, and tablets of an active and said binder having advantageous hardness and friability
ES2738659T3 (es) * 2013-03-12 2020-01-24 Hercules Llc Composición de polímero revestida con sílice co-procesada

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU183408B (en) * 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
US5326570A (en) * 1991-07-23 1994-07-05 Pharmavene, Inc. Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
US6221399B1 (en) * 1995-08-17 2001-04-24 Csir Method of making controlled release particles of complexed polymers
AT413647B (de) * 1998-11-26 2006-04-15 Sandoz Ag Verwendung eines copolymerisats aus 1-vinyl-2-pyrrolidon und vinylacetat zur herstellung von cefuroximaxetil-hältigen tabletten

Also Published As

Publication number Publication date
EP1416918A4 (en) 2004-08-18
CN1556695A (zh) 2004-12-22
CA2454449C (en) 2010-10-26
BRPI0211439B1 (pt) 2017-09-19
EP1416918A1 (en) 2004-05-12
RU2304981C2 (ru) 2007-08-27
US20030031708A1 (en) 2003-02-13
MXPA04000666A (es) 2004-04-05
ES2266502T3 (es) 2007-03-01
JP2005501049A (ja) 2005-01-13
DE60211916D1 (de) 2006-07-06
WO2003011253A1 (en) 2003-02-13
BRPI0211439B8 (enExample) 2021-05-25
ATE327738T1 (de) 2006-06-15
BR0211439A (pt) 2004-07-20
EP1416918B1 (en) 2006-05-31
US6524617B1 (en) 2003-02-25
RU2004105268A (ru) 2005-03-10
CA2454449A1 (en) 2003-02-13
DE60211916T2 (de) 2007-01-04
JP4805537B2 (ja) 2011-11-02

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20060809