CN1236615A - Exterior-applied medicine for treating dermatosis and its preparing process. - Google Patents
Exterior-applied medicine for treating dermatosis and its preparing process. Download PDFInfo
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- CN1236615A CN1236615A CN 98101954 CN98101954A CN1236615A CN 1236615 A CN1236615 A CN 1236615A CN 98101954 CN98101954 CN 98101954 CN 98101954 A CN98101954 A CN 98101954A CN 1236615 A CN1236615 A CN 1236615A
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- medicine
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- metronidazole
- griseofulvin
- dexamethasone
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Abstract
An external use medicine for treating dermatosis such as dermatitis, eczema, acne and sore is prepared from vanishing cream as basic raw material, cimetidine, metronidazole, dexamethasone, griseofulvin, VE and hydrocinnamyl BHC through mixing uniformly. It has high curative effect (total effective rate up to 98%).
Description
The invention belongs to field of medicaments, dermopathic medicine for external use of a kind of specifically treatment and preparation technology.
Dermatosis is a commonly encountered diseases, and frequently-occurring disease has two or three dried kinds more than approximately, almost everyone shares the weal and woe together on the spot in person and has or have one to two kind of dermatosis, dermatosis has certain influence to the health of human body, gently then influences attractive in appearance, overslaugh rest, influences work, and is heavy what for to threat to life.Modal dermatosis has eczema, erysipelas, acute urticaria, neurodermatitis, folliculitis, tinea manus and pedis, herpes zoster and old people's skin pruritus etc.
Because it is a lot of that dermatosis not only generally but also easily recurrence, is treated dermopathic medicine, but mostly effect is undesirable; And life-time service easily develops immunity to drugs.
The object of the present invention is to provide a kind of dermopathic medicine for external use of a kind of treatment that common skin diseases is had good efficacy and is difficult for developing immunity to drugs.
The objective of the invention is to realize in the following manner: the dermopathic medicine for external use of a kind of treatment, this medicine comprises following raw material, its proportioning (weight portion) is:
Cimetidine 4-8 metronidazole 2-4 vitamin E 60-600 dexamethasone 4.4-45
Griseofulvin 0.2-2 copper health azoles 0.1-2 phenylpropyl alcohol Gamma Hexaochlorocyclohexane powder 0.1-1 vanishing cream 1000-3000
The technology for preparing described external used medicine is:
A: JIAQINGMIGUA PIAN, metronidazole sheet, dexamethasone tablet, griseofulvin tablet are ground into fine powder respectively, are mixed into the A material by proportioning.
B: vitamin E capsule cut off get oil, mix phenylpropyl alcohol Gamma Hexaochlorocyclohexane powder, make the B material by proportioning.
C: by proportioning A material, B material are added in the base material vanishing cream, stir, make required external used medicine.
Cimetidine among the present invention is a kind of oral medicine that is used for diseases such as stomach, duodenal ulcer, gastrorrhagia, but finds that in clinical it has certain effect to skin disorders such as acne, eczemas; The anti-ameba of metronidazole (metronidazole), trichomonas vaginitis have obvious antibacterial action to most anaerobe.Diseases such as this medicine for oral administration, idol have headache, xerostomia, feel sick have neuropathy and hemopathic forbidding.But external cooperates cimetidine and other several drugses of the present invention then to have an effect of antiinflammatory, antipruritic, parasite killing, and dermatitis, eczema, acne, herpes are waited until the tool good efficacy, and clinical observation is summarized as follows:
One, clinical data
Among the 200 routine patients, male 146 people, women 54 people, minimum 5 months, maximum 72 years old; Eczema patients (acute, dislike acute, chronic) 72 examples wherein; Tinea manus and pedis, tinea corporis and cruris 56 examples; Herpes zoster 20 examples; Acute urticaria, folliculitis, acne, neurodermatitis, erysipelas 52 examples.
Above-mentioned 200 routine patients are divided into two groups, and every group 100 people treats with the present invention for one group, is the treatment group; Another group is matched group.
The treatment group: external medicine of the present invention is applied to the affected part, and every day 2-3 time, 7 is a course of treatment.Cooperate Yinqiao detoxification soup for oral administration therebetween.
Matched group: external propanoic acid Betamethasone emulsifiable paste (Tianjin strong people pharmaceutical factory produce) every day 2-3 time, 7 days one courses of treatment.Cooperate Yinqiao detoxification soup for oral administration therebetween.
Stop for oral administration and medicine for external use during above-mentioned two groups of treatments, judge curative effect after treating three courses of treatment with other.
Criterion of therapeutical effect and therapeutic outcome:
1. curative effect determinate standard: recovery from illness: clinical symptoms complete obiteration, subjective symptoms complete obiteration; Produce effects: clinical symptoms disappears substantially, and subjective symptoms disappears substantially; Take a turn for the better: clinical symptom relief; Invalid: clinical symptoms does not have improvement.
2. result: the treatment group, cure 89 examples (89%), produce effects 6 examples (6%), invalid 2 examples of 3 examples that take a turn for the better (3%) (2%)
Matched group: cure 50 examples (50%), produce effects 20 examples (20%), 8 examples that take a turn for the better (8%), invalid 22 examples (22%)
Healing time: the treatment group is the shortest 3 days, and is the longest 10 days, and average 6.5 days
Matched group is the shortest 10 days, and is the longest 30 days, average 20 days.
Sum up: the present invention has instant effect, nontoxic pair of effect, and good effect, short treating period, the advantage that expense is lower, and recurrence rate after healing is low.
Embodiment one:
JIAQINGMIGUA PIAN 0.8g, Metronidazole Tablet 0.2g, dexamethasone tablet 4.5g, griseofulvin tablet 0.2g, copper health azoles sheet 0.1g are ground into fine powder, are mixed into the A material;
Vitamin E capsule is cut off, got vitamin E oil 60g, add phenylpropyl alcohol Gamma Hexaochlorocyclohexane powder 0.1g, make the B material.
A, B material is added in the vanishing cream, stir, make required medicine.
Embodiment two:
JIAQINGMIGUA PIAN 8g, Metronidazole Tablet 4g, dexamethasone tablet 45g, griseofulvin tablet 20, copper health azoles sheet 1g are ground into fine powder, are mixed into the A material;
Vitamin E capsule is cut off, got vitamin E oil 600g, add phenylpropyl alcohol Gamma Hexaochlorocyclohexane powder 1g, make the B material.
A, B material is added in the vanishing cream, stirs, add again Borneolum Syntheticum a little, make required medicine.
Claims (2)
1. treat dermopathic medicine for external use for one kind, its thing is levied and is that this medicine comprises following raw material, and its proportioning (weight portion) is:
The plain E 60-600 of the little life of cimetidine 4-8 metronidazole 2-4 dexamethasone 4.4-45
Griseofulvin 0.2-2 copper health azoles 0.1-2 phenylpropyl alcohol Gamma Hexaochlorocyclohexane powder 0.1-1 vanishing cream 1000-3000
2. technology for preparing external used medicine as claimed in claim 1 is characterized in that:
A: JIAQINGMIGUA PIAN, metronidazole sheet, dexamethasone tablet, griseofulvin tablet are ground into fine powder respectively, are mixed into the A material by proportioning.
B: vitamin E capsule cut off get oil, mix phenylpropyl alcohol Gamma Hexaochlorocyclohexane powder, make the B material by proportioning.
C: by proportioning A material, B material are added in the base material vanishing cream, stir, make required external used medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98101954 CN1236615A (en) | 1998-05-22 | 1998-05-22 | Exterior-applied medicine for treating dermatosis and its preparing process. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98101954 CN1236615A (en) | 1998-05-22 | 1998-05-22 | Exterior-applied medicine for treating dermatosis and its preparing process. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1236615A true CN1236615A (en) | 1999-12-01 |
Family
ID=5217037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 98101954 Pending CN1236615A (en) | 1998-05-22 | 1998-05-22 | Exterior-applied medicine for treating dermatosis and its preparing process. |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1236615A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264049B (en) * | 2007-03-13 | 2010-11-10 | 李春风 | Multifunctional beauty treatment cream |
-
1998
- 1998-05-22 CN CN 98101954 patent/CN1236615A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264049B (en) * | 2007-03-13 | 2010-11-10 | 李春风 | Multifunctional beauty treatment cream |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |