CN1220703A - Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions theirof - Google Patents

Abstract

Recombinant or substantially pure preparations of H. pylori polypeptides are described. The nucleic acids encoding the polypeptides also are described. The H. pylori polypeptides are useful in diagnostic and vaccine compositions.

Description

Nucleic acid and amino acid sequences related to helicobacter pylori and vaccine compositions thereof

Background

Helicobacter pylori is a gram-negative, sigmoidal, microaerophilic bacterium that has been found and cultured in a human gastric biopsy (Warren, J.R. and B.Marshall, (1983) Lancet 1: 1273-. Helicobacter pylori is very involved in chronic gastritis and duodenal ulcer disease. (Rathbone et al (1986) digestion 27, 635-641). Furthermore, evidence is accumulating about the etiological role of H.pylori in non-ulcer dyspepsia, gastric ulcer disease, and gastric adenocarcinoma (blast M.J., (1993) trends in microbiology 1, page 255-260). Bacteria are transmitted via the fecal-oral route and the risk of infection increases with age. (Taylor, D.N. and M.J.Blaster, (1991) Rev.Epideological review of infectious diseases, pp.13, 42-50). Helicobacter pylori colonises the human gastric mucosa, establishing an infection that usually lasts for decades. Infection with H.pylori is prevalent worldwide. The infection rate in developed countries exceeds 50% in the adult population, while the infection rate in developing countries reaches 90% in adults over 20 years of age. (Hopkins R.J. and J.G.Morris (1994) J.Med.97, page 265. 277).

Little is known about the bacterial factors necessary for colonization and virulence of the pathogen in the gastric environment. Examples of recognized virulence factors include the following: urease, an enzyme that may play a role in neutralizing gastric acid pH (Eaton et al, (1991) infection andimmunity 59, 2470&2475; Ferero, R.L. and A.Lee (1991) Microb. Eclo. Hlth. Dis 4, 121&134; Labigne et al, (1991) journal of bacteriology 173, 1920&1931); bacterial flagellins responsible for movement across mucosal layers (Hazell et al, J. infectious diseases 153, pages 658&663; Leying et al, (1992) molecular microbiology 6, pages 2863&2874; and Haas et al, (1993) molecular microbiology 8, pages 753&760); VacA, a bacterial toxin that induces intracellular vacuolation in epithelial cells (Schmitt, W and R.Haas, (1994) molecular microbiology 12 (2), pp.307-319); and several gastric tissue specific adhesins. (Boren et al, (1993) science 262 volume 1892 pages 1895; Evans et al, (1993) journal of bacteriology 175 volume 674 pages 683; and Folk et al, (1993) Proc. Natl. Acad. Sci. USA 90 volume 2035 pages 203).

A large number of therapeutic agents are currently available for the in vitro elimination of H.pylori (Huesca et al, (1993) Zbl. Bakt. 280, pp. 244&252; Hopkins, R.J. and J.G.Morris, supra). However, many of them do not achieve optimal effects in vivo due to bacterial resistance, altered drug distribution, patient non-compliance or drug inapplicability (Hopkins, r.j. and j.g. morris, supra). Treatment with an antibiotic in combination with a bismuth agent is part of the standard therapy for the treatment of H.pylori infections (Malfertheiner. P and J.E.dominguez-Munoz, (1993) clinical treatment, volume 15 suppl B, pages 37-48). Recently, the combination of an ion pump inhibitor and a single antibiotic has been shown to alleviate duodenal disease ((male filter. p and j.e.dominguez-Munoz, supra.) however, methods using antibiotic drugs may suffer from the problem that bacterial strains resistant to these drugs arise (Hopkins, r.j. and j.g.morris, supra.) these limitations indicate that there is a need for new, more effective methods of combating helicobacter pylori infection in vivo, and in particular a great need to design new vaccines that can prevent such bacterial infection.

Brief description of the invention

The present invention relates to novel genes from the organism Helicobacter pylori (Helicobacter pylori), for example, genes encoding polypeptides such as bacterial surface proteins, and other related genes; the product thereof; and uses thereof. The nucleic acids and peptides of the invention are useful in the diagnosis and treatment of helicobacter pylori and other helicobacter species. They can also be used to detect the presence of helicobacter pylori and other helicobacter species in a sample; and for screening compounds capable of interfering with the life cycle of helicobacter pylori or inhibiting helicobacter pylori infection. Specifically, the present invention relates to the composition of nucleic acids corresponding to the entire coding region of helicobacter pylori protein, including surface protein or secretory protein or a part thereof, nucleic acids capable of binding to the mRNA of helicobacter pylori protein to thereby inhibit the translation of the protein, and a method for producing helicobacter pylori protein or a part thereof using peptide synthesis and recombinant DNA technology. The present invention also details antibodies and nucleic acids that can be used as probes for detecting H.pylori infection. In addition, vaccine compositions and methods for providing protection against H.pylori infection are also within the scope of the present invention.

Brief Description of Drawings

FIG. 1 is a bar graph depicting antibody titers in the sera of mice immunized with specific H.pylori antigens.

FIG. 2 is a bar graph depicting antibody titers in the mucosaof mice following immunization with specific H.pylori antigens.

FIG. 3 is a bar graph depicting therapeutic immunization of H.pylori infected mice with specific antigens dissolved in HEPES buffer.

FIG. 4 is a bar graph depicting therapeutic immunization of H.pylori-infected mice with specific antigens solubilized with buffer containing DOC.

FIG. 5 is a graph depicting the activity of recombinant PPIase.

FIG. 6 is a graph depicting PPIase activity in an extract of helicobacter pylori.

FIG. 7 is a graph depicting the reduction of glutamate racemase activity by L-serine-O-sulfuric acid.

FIG. 8 is a diagram depicting the amino acid sequence arrangement (indicated by the one-letter amino acid code; and designated by their amino acid sequence ID numbers; from left to right, from the N-terminus to the C-terminus) in the partial sequence of 12 H.pylori proteins.

FIG. 9 depicts the N-terminal part of the 9 H.pylori proteins (indicated by the one-letter amino acid codes; and designated by their amino acid sequence ID numbers; from left to right, N-terminal to C-terminal is shown).

Detailed Description

In one aspect, the invention features a recombinant or substantially pure preparation of the H.pylori polypeptide SEQ ID NO: 492. The invention also includes a substantially pure nucleic acid encoding the H.pylori polypeptide SEQ ID NO. 492, which is contained in SEQ ID NO. 1. The H.pylori polypeptide sequences presented herein are included in the sequence listing, as are the nucleic acids encoding the H.pylori polypeptides.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the helicobacter pylori polypeptide SEQ ID NO:492 to SEQ ID NO: 541. The invention also includes substantially pure nucleic acids encoding a polypeptide selected from the group consisting of H.pylori polypeptide SEQ ID NO:492 to SEQ ID NO:541, which nucleic acids are comprised in SEQ ID NO:1 to SEQ ID NO: 50.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the helicobacter pylori polypeptides SEQ ID NO:542 through SEQ ID NO: 591. The invention also encompasses substantially pure nucleic acids encoding a helicobacter pylori polypeptide selected from the group consisting of SEQ ID NO 542 to SEQ ID NO 591, which nucleic acids are comprised in SEQ ID NO 51 to SEQ ID NO 100.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the helicobacter pylori polypeptides SEQ ID NO:592 to SEQ ID NO: 641. The invention also includes substantially pure nucleic acids encoding a helicobacter pylori polypeptide selected from SEQ ID NO. 592 to SEQ ID NO. 641, which nucleic acids are comprised in SEQ ID NO. 101 to SEQ ID NO. 150.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the group consisting of the helicobacter pylori polypeptides SEQ ID NO 642 to SEQ ID NO 691. The invention also encompasses substantially pure nucleic acids encoding a polypeptide selected from the group consisting of H.pylori polypeptides SEQ ID NO 642 to SEQ ID NO 691, which nucleic acids are comprised in SEQ ID NO 151 to SEQ ID NO 200.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the group consisting of the helicobacter pylori polypeptides SEQ ID NO. 692 to SEQ ID NO. 741. The invention also encompasses substantially pure nucleic acids encoding a polypeptide selected from the group consisting of H.pylori polypeptides SEQ ID NO 692 to SEQ ID NO 741, the nucleic acids being comprised in SEQ ID NO 201 to SEQ ID NO 250.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the group consisting of the helicobacter pylori polypeptides SEQ ID NO:742 to SEQ ID NO:759, SEQ ID NO:761, SEQ ID NO:763, SEQ ID NO:765 to SEQ ID NO: 791. The invention also encompasses substantially pure nucleic acids encoding a polypeptide selected from the group consisting of H.pylori polypeptide SEQ ID NO:742 to SEQ ID NO:759, SEQ ID NO:761, SEQ ID NO:763, SEQ ID NO:765 to SEQ ID NO:791, as comprised in SEQ ID NO:251 to SEQ ID NO:268, SEQ ID NO:270, SEQ ID NO:272 and SEQ ID NO:274 to SEQ ID NO: 300.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the group consisting of the helicobacter pylori polypeptide SEQ ID NO. 792 through SEQ ID NO. 818 and SEQ ID NO. 820 through SEQ ID NO. 841. The invention also encompasses substantially pure nucleic acids encoding a polypeptide selected from the group consisting of H.pylori polypeptide SEQ ID NO. 792 to SEQ ID NO. 818 and SEQ ID NO. 820 to SEQ ID NO. 841, which nucleic acids are comprised in SEQ ID NO. 301 to SEQ ID NO. 327 and SEQ ID NO. 329 to SEQ ID NO. 350.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the group consisting of the helicobacter pylori polypeptides of SEQ ID NO:842 to SEQ ID NO:846 and SEQ ID NO:848 to SEQ ID NO: 891. The invention also encompasses substantially pure nucleic acids encoding a polypeptide selected from the group consisting of the H.pylori polypeptides SEQ ID NO 842 to 846 and SEQ ID NO 848 to SEQ ID NO 891, which nucleic acids are comprised in SEQ ID NO 351 to SEQ ID NO 364 and SEQ ID NO 366 to SEQ ID NO 400.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the group consisting of the helicobacter pylori polypeptide SEQ ID NO:892 through SEQ ID NO:896 and SEQ ID NO:898 through SEQ ID NO: 941. The invention also includes substantially pure nucleic acids encoding a polypeptide selected from the group consisting of the helicobacter pylori polypeptides SEQ ID NO:892 through SEQ ID NO:896 and SEQ ID NO:898 through SEQ ID NO:941, as contained in SEQ ID NO:401 through SEQ ID NO:405 and SEQ ID NO:407 through SEQ ID NO: 450.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the group consisting of the helicobacter pylori polypeptides SEQ ID NO:942 to SEQ ID NO:963 and SEQ ID NO:966 to SEQ ID NO: 982. The invention also encompasses substantially pure nucleic acids encoding a polypeptide selected from the group consisting of the H.pylori polypeptide SEQ ID NO 942 to 963 and SEQ ID NO 966 to 982 as comprised in SEQ ID NO 451 to 472 and SEQ ID NO 475 to 491.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the group consisting of the helicobacter pylori polypeptide SEQ ID NO 1037, SEQ ID NO 1038, SEQ ID NO 1041 through SEQ ID NO 1087, and SEQ ID NO 1090. The invention also includes substantially pure nucleic acids encoding a polypeptide selected from the group consisting of the H.pylori polypeptides SEQ ID NO 1037, SEQ ID NO 1038, SEQ ID NO 1041 through to SEQ ID NO 1087 and SEQ ID NO 1090, which nucleic acids are comprised in SEQ IDNO 983, SEQ ID NO 984, SEQ ID NO 987 through to SEQ ID NO 1033 and SEQ ID NO 1036.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the helicobacter pylori polypeptide SEQ ID NO:1296 through SEQ ID NO: 1298. The invention also encompasses substantially pure nucleic acids encoding a polypeptide selected from the group consisting of H.pylori polypeptide SEQ ID NO:1296 to SEQ ID NO:1298, which nucleic acids are comprised in SEQ ID NO:1293 to SEQ ID NO: 1295.

In another aspect, the invention features recombinant or substantially pure preparations of a helicobacter pylori polypeptide selected from the helicobacter pylori polypeptides listed in the sequence listing. The invention also includes substantially pure nucleic acids encoding a helicobacter pylori polypeptide selected from the group consisting of those listed in the sequence listing. It will be appreciated that the invention encompasses each H.pylori polypeptide identified by a given sequence identification number in the sequence listing and the nucleic acids encoding these polypeptides. For example, a representative H.pylori polypeptide is contained in SEQ ID NO: 494. Thus, the present invention encompasses recombinant or substantially pure preparations of the H.pylori polypeptide SEQ ID NO: 494. The invention also encompasses substantially pure nucleic acids encoding the H.pylori polypeptide SEQ ID NO: 494.

In another aspect, the present invention relates to any individual H.pylori polypeptide member of the above-identified H.pylori polypeptide family (e.g., SEQ ID NO:542-SEQ ID NO:591) or nucleic acid family (e.g., SEQ ID NO:51-SEQ ID NO:100) and nucleic acids encoding such members as well as any subfamily within the above-identified family. Furthermore, a sub-family may preferably comprise members of any of the families identified above, 1,3,5,10, 15, 20, 30 or 40, and any combination thereof. For example, the family consisting of H.pylori polypeptides SEQ ID NO 692 to SEQ ID NO 741 may be divided into one or more subfamilies SEQ ID NO 692-680, SEQ ID NO 681 to SEQ ID NO 710, SEQ ID NO 711 to SEQ ID NO 730, SEQ ID NO 731 to SEQ ID NO 741 or any combination thereof.

Particularly preferred is an isolated nucleic acid comprising a nucleotide sequence encoding a H.pylori cell envelope polypeptide or a fragment thereof. The nucleic acid is selected from the group consisting of SEQ ID NO 255, SEQ ID NO 263, SEQ ID NO 266, SEQ ID NO 277, SEQ ID NO 280, SEQ ID NO 285, SEQ ID NO 292, SEQ ID NO 294, SEQ ID NO 299, SEQ ID NO 311, SEQ ID NO 312, SEQ ID NO 313, SEQ ID NO 321, SEQ ID NO 327, SEQ ID NO 329, SEQ ID NO 331, SEQ ID NO 353, SEQ ID NO 364, SEQ ID NO 366, SEQ ID NO 368, SEQ ID NO 375, SEQ ID NO 384, SEQ ID NO 391, SEQ ID NO 392, SEQ ID NO 397, SEQ ID NO 398, SEQ ID NO 402, SEQ ID NO 404, SEQ ID NO 409, SEQ ID NO 410, SEQ ID NO 412, SEQ ID NO 427, SEQ ID NO 433, 434, 441, 444, 445, 449, 450, 452, 453, 466, 468, 469, 983, 989, 1008, 1011, 1014, 1015, 1029, 1032, 259, 286, 326, 374, 422, 454, 465, 998, 1009, 1023, 1294, 1295, 319, 325, 1294, 1295, 319, 325, 425, 437, 438, 447, 448, 467, 996, 1027, 1031, 254, 352, 415, 1019, 381, 389, 101, 1012, 354, 372, 400, 421, 1025, 463, 281, 988, 411, 407, 1017, 290, 417, 430, 992, 1025, 463, 281, 1025, 407, 1017, 290, 417, 430, 992, 1025, 2, SEQ ID NO 477, SEQ ID NO 414, SEQ ID NO 253, SEQ ID NO 293, SEQ ID NO 334, SEQ ID NO 343, SEQ ID NO 418, SEQ ID NO 424 and SEQ ID NO 443.

In another embodiment, the H.pylori cell envelope polypeptide or fragment thereof is a H.pylori outer membrane polypeptide or fragment thereof encoded by a nucleic acid selected from the group consisting of: 255, 263, 266, 277, 280, 285, 292, 294, 299, 311, 312, 313, 321, 327, 329, 331, 353, 364, 366, 368, 375, 384, 391, 392, 397, 409, 398, 402, 404, 409, 410, 412, 427, 433, 434, 441, 444, 445, 449, 983, 989, 1008, 1011, 1014, 1015, 1029, 1032, 259, 286, 326, 374, 422, 454, 465, 998, 1298, 1023, 1294, 1295, 319, 1294, 1295, 319, 425, 437, 438, 447, 448, 467, 996, 1027, 1031, 254, 352, 415, 1019, 381, 389, 1010 and 1012.

In another embodiment, the H.pylori outer membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof having a terminal phenylalanine residue encoded by a nucleic acid selected from the group consisting of: 255, 263, 266, 277, 280, 285, 292, 294, 299, 311, 312, 313, 321, 327, 329, 331, 353, 364, 366, 368, 375, 384, 391, 392, 375, 384, 391, 392, 397, 398, 402, 404, 409, 410, 412, 427, 433, 434, 441, 444, 445, 449, 983, 989, 1008, 1011, 1014, 1015, 1029 and 1032 SEQ ID NO.

In another embodiment, the H.pylori outer membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof having a C-terminal tyrosine cluster encoded by a nucleic acid selected from the group consisting of: 286 SEQ ID NO, 326 SEQ ID NO, 374 SEQ ID NO, 399 SEQ ID NO, 422 SEQ ID NO, 454 SEQ ID NO, 465 SEQ ID NO, 998 SEQ ID NO, 1009 SEQ ID NO, 1023 SEQ ID NO, 1294 SEQ ID NO and 1295 SEQ ID NO.

In another embodiment, the H.pylori outer membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof having a terminal phenylalanine residue and a C-terminal tyrosine cluster encoded by a nucleic acid selected from the group consisting of SEQ ID NO 319, SEQ ID NO 325, SEQ ID NO 425, SEQ ID NO 437, SEQ ID NO 438, SEQ ID NO 447, SEQ ID NO 448, SEQ ID NO 467, SEQ ID NO 996, SEQ ID NO 1O27 and SEQ ID N0: 1031.

In another embodiment, the H.pylori cell envelope polypeptide or fragment thereof is a H.pylori inner membrane polypeptide or fragment thereof encoded by a nucleic acid selected from the group consisting of SEQ ID NO 354, SEQ ID NO 372,SEQ ID NO 400, SEQ ID NO 421, SEQ ID NO 1022, SEQ ID NO 463, SEQ ID NO 281, SEQ ID NO 988, SEQ ID NO 411, SEQ ID NO 407, SEQ ID NO 1017, SEQ ID NO 290, SEQ ID NO 417, SEQ ID NO 430, SEQ ID NO 992 and SEQ ID NO 1025.

In another embodiment, the H.pylori inner membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof involved in outer membrane and cell wall synthesis encoded by a nucleic acid comprising the nucleotide sequence of SEQ ID NO. 354.

In another embodiment, the H.pylori inner membrane polypeptide or a fragment thereof is a H.pylori polypeptide or a fragment thereof involved in energy conversion encoded by a nucleic acid selected from the group consisting of SEQ ID NO:372, SEQ ID NO:400, SEQ ID NO:421 and SEQ ID NO: 1022.

In another embodiment, the H.pylori inner membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof involved in cofactor metabolism encoded by a nucleic acid comprising the nucleotide sequence of SEQ ID NO: 463.

In another embodiment, the H.pylori inner membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof involved in secretion or adhesion encoded by a nucleic acid selected from the group consisting of SEQ ID NO. 281 and SEQ ID NO. 988.

In another embodiment, the H.pylori inner membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof involved in trafficking encoded by a nucleic acid selected from the group consisting of SEQ ID NO:407 and SEQ ID NO: 1017.

In another embodiment, the H.pylori cell envelope polypeptide or fragment thereof is the H.pylori flagella polypeptide or fragment thereof encoded by the nucleic acid comprising the nucleotide sequence of SEQ ID NO: 477.

In another embodiment, the H.pylori cell envelope polypeptide or fragment thereof is the H.pylori-transporting polypeptide or fragment thereof encoded by the nucleic acid comprising the nucleotide sequence of SEQ ID NO: 414.

Particularly preferred is an isolated nucleic acid comprising a nucleotide sequence encoding a cytoplasmic polypeptide of helicobacter pylori or a fragment thereof, selected from the group consisting of SEQ ID NO 470, SEQ ID NO 1033, SEQ ID NO 357, SEQ ID NO 457, SEQ ID NO 461, SEQ ID NO 1030, SEQ ID NO 345, SEQ ID NO 383, SEQ ID NO 387, SEQ ID NO 455, SEQ ID NO 1003, SEQ ID NO 351, SEQ ID NO 416, SEQ ID NO 278, SEQ ID NO 335, SEQ ID NO 346, SEQ ID NO 350, SEQ ID NO 419, SEQ ID NO 460, SEQ ID NO 472, SEQ ID NO 1000, SEQ ID NO 1004, SEQ ID NO 1020, SEQ ID NO 1293, SEQ ID NO 318, SEQ ID NO 322, SEQ ID NO 324, SEQ ID NO 330, SEQ ID NO 1000, SEQ ID NO 1004, SEQ ID NO 1020, SEQ ID NO 1293, SEQ ID NO 318, SEQ ID NO 322, SEQ ID NO 324, SEQ ID NO 330, SEQ ID NO, 347, 440, 446, 464, 490, 491, 995, 997, 1005 and 1028 amino acid sequences.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in energy conversion encoded by a nucleic acid selected from the group consisting of SEQ ID NO. 470 and SEQ ID NO. 1033.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in amino acid metabolism and transport encoded by a nucleic acid selected from the group consisting of SEQ ID NO:357 and SEQ ID NO: 457.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in nucleotide metabolism and transport encoded by a nucleic acid selected from the group consisting of SEQ ID NO. 461 and SEQ ID NO. 1030.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in cofactor metabolism encoded by a nucleic acid selected from the group consisting of SEQ ID NO 345, SEQ ID NO 383, SEQ ID NO 387, SEQ ID NO 455, and SEQ ID NO 1003.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in lipid metabolism encoded by a nucleic acid selected from the group consisting of SEQ ID NO. 351 and SEQ ID NO. 416.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in replication, transcription, recombination and repair of the genome encoded by a nucleic acid selected from the group consisting of SEQ ID NO 278, SEQ ID NO 335, SEQ ID NO 346, SEQ ID NO 350, SEQ ID NO 419, SEQ ID NO 460, SEQ ID NO 472, SEQ ID NO 1000, SEQ ID NO 1004, SEQ ID NO 1020 and SEQ ID NO 1293.

Particularly preferred is an isolated nucleic acid comprising a nucleotide sequence encoding a helicobacter pylori secretory peptide or a fragment thereof, selected from the group consisting of SEQ ID NO 355, SEQ ID NO 1006, SEQ ID NO 257, SEQ ID NO 258, SEQ ID NO 260, SEQ ID NO 261, SEQ ID NO 264, SEQ ID NO 265, SEQ ID NO 268, SEQ ID NO 270, SEQ ID NO 272, SEQ ID NO 274, SEQ ID NO 275, SEQ ID NO 276, SEQ ID NO 279, SEQ ID NO 283, SEQ ID NO 284, SEQ ID NO 287, SEQ ID NO 288, SEQ ID NO 289, SEQ ID NO 291, SEQ ID NO 295, SEQ ID NO 296, SEQ ID NO 297, SEQ ID NO 298, SEQ ID NO 300, SEQ ID NO 301, SEQ ID NO 302, SEQ ID NO, SEQ ID NO 303, 304, 305, 314, 315, 323, 338, 342, 348, 349, 356, 358, 359, 360, 361, 362, 363, 367, 370, 371, 373, 377, 378, 379, 380, 388, 390, 394, 401, 403, 405, 408, 405, 394, 395, 396, 401, 403, 408, 401, 403, 405,408, and, SEQ ID NO 420, SEQ ID NO 426, SEQ ID NO 428, SEQ ID NO 429, SEQ ID NO 432, SEQ ID NO 439, SEQ ID NO 442, SEQ ID NO 451, SEQ ID NO 471, SEQ ID NO 478, SEQ ID NO 488, SEQ ID NO 987, SEQ ID NO 990, SEQ ID NO 991, SEQ ID NO 993, SEQ ID NO 1001, SEQ ID NO 1002, SEQ ID NO 1007, SEQ ID NO 1013, SEQ ID NO 1016, SEQ ID NO 1018, SEQ ID NO 1021, and SEQ ID NO 1026.

In another embodiment, the H.pylori secreting peptide or fragment thereof is a H.pylori polypeptide or fragment thereof involved in secretion and adhesion encoded by a nucleic acid selected from the group consisting of SEQ ID NO:355 and SEQ ID NO: 1006.

Particularly preferred is an isolated nucleic acid comprising a nucleotide sequence encoding a H.pylori cellular polypeptide or a fragment thereof, selected from the group consisting of SEQ ID NO 256, SEQ ID NO 267, SEQ ID NO 282, SEQ ID NO 306, SEQ ID NO 307, SEQ ID NO 308, SEQ ID NO 309, SEQ ID NO 310, SEQ ID NO 316, SEQ ID NO 317, SEQ ID NO 332, SEQ ID NO 333, SEQ ID NO 336, SEQ ID NO 337, SEQ ID NO 339, SEQ ID NO 340, SEQ ID NO 341, SEQ ID NO 344, SEQ ID NO 369, SEQ ID NO 376, SEQ ID NO 382, SEQ ID NO 386, SEQ ID NO 423, SEQ ID NO 431, SEQ ID NO 435, SEQ ID NO 436, SEQ ID NO 458, SEQ ID NO 462, 475, 476, 479, 480, 481, 482, 483, 484, 485, 486, 487, 489, 984, 994, 1024 and 1036 SEQ ID NOs.

Particularly preferred is a pure or isolated H.pylori cell envelope polypeptide or a fragment thereof, wherein the polypeptide is selected from the group consisting of SEQ ID NO 746, SEQ ID NO 754, SEQ ID NO 757, SEQ ID NO 768, SEQ ID NO 771, SEQ ID NO 776, SEQ ID NO 783, SEQ ID NO 785, SEQ ID NO 790, SEQ ID NO 802, SEQ ID NO 803, SEQ ID NO 804, SEQ ID NO 812, SEQ ID NO 818, SEQ ID NO 820, SEQ ID NO 882, SEQ ID NO 844, SEQ ID NO 855, SEQ ID NO 857, SEQ ID NO 859, SEQ ID NO 866, SEQ ID NO 875, SEQ ID NO 882, SEQ ID NO 883, SEQ ID NO 888, SEQ ID NO 889, SEQ ID NO 893, SEQ ID NO 895, SEQ ID NO 900, SEQ ID NO 893, SEQ ID NO 89900, SEQ ID NO 893, SEQ ID NO 889, 901 SEQ ID NO, 903 SEQ ID NO, 918, 924, 925, 932, 935, 936, 94, 941, 943, 944, 957, 959, 960, 1037, 1043, 1062, 1065, 1068, 1069, 1083, 1086, 750, 777, 817, 865, 890, 913, 945, 1068, 1069, 1063, 1083, 956, 1052, 1063, 1069, 1066, 865, 890, 913, 945, 956, 1052, 1063, 1077, 1297, 1298, 810, 816, 916, 928, 929, 938, 939, 958, 1050, 1081, 1085, 745, 843, 906, 1071071073, 872, 880, 1064, 1066, 7816, 954, 772, 1042, 902, 880, 1064, 1066, 845, 863, 891, 912, 7816, 781772, 1042, 902, 898, 891, 1071, 1071042, 1076, 908, 921, 1046, 1079, 968, 905, 744, 784, 825, 834, 909, 915 and 934.

In another embodiment the H.pylori cell envelope polypeptide or fragment thereof is a H.pylori outer membrane polypeptide or fragment thereof selected from the group consisting of: 746 SEQ ID NO, 754 SEQ ID NO, 757 SEQ ID NO, 768 SEQ ID NO, 771 SEQ ID NO, 776 SEQ ID NO, 783 SEQ ID NO, 785 SEQ ID NO, 790 SEQ ID NO, 802 SEQ ID NO, 803 SEQ ID NO, 804 SEQ ID NO, 812 SEQ ID NO, 818 SEQ ID NO, 820 SEQ ID NO, 882 SEQ ID NO, 844 SEQ ID NO, 855 SEQ ID NO, 857 SEQ ID NO 859, 866 SEQ ID NO, 875 SEQ ID NO, 882 SEQ ID NO, 883 SEQ ID NO, 888 SEQ ID NO, 889 SEQ ID NO, 893 SEQ ID NO 895, 895 SEQ ID NO 900, 901 SEQ ID NO, 903 SEQ ID NO, 918, SEQ ID NO 925, SEQ ID NO, 932, 935, 936, 940, 941, 943, 944, 957, 959, 960, 1037, 1033, 1083, 1062, 1065, 1068, 1069, 1083, 1086, 750, 777, 817, 865, 956, 913, 945, 1052, 1063, 1073, 1077, 1071297, 1297, 1298, 129913, 945, 1071079, 1071073, 1071071071071071071071071071071077, 1297, 1298, 810, 816, 916, 928, 929, 938, 939, 958, 1050, 1081, 1085, 745, 843, 906, 1073, 872, 880, 1064 and 1066.

In another embodiment, the helicobacter pylori outer membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof having a terminal phenylalanine residue selected from the group consisting of: 746 SEQ ID NO, 754 SEQ ID NO, 757 SEQ ID NO, 768 SEQ ID NO, 771 SEQ ID NO, 776 SEQ ID NO, 783 SEQ ID NO, 785 SEQ ID NO, 790 SEQ ID NO, 802 SEQ ID NO, 803 SEQ ID NO, 804 SEQ ID NO, 812 SEQ ID NO, 818 SEQ ID NO, 820 SEQ ID NO, 882 SEQ ID NO, 844 SEQ ID NO, 855 SEQ ID NO, 857 SEQ ID NO 859, 866 SEQ ID NO, 875 SEQ ID NO, 882 SEQ ID NO, 883 SEQ ID NO, 888 SEQ ID NO, 889 SEQ ID NO, 893 SEQ ID NO 895, 895 SEQ ID NO 900, 901 SEQ ID NO, 903 SEQ ID NO, 918, SEQ ID NO 925, SEQ ID NO, 932, 935, 936, 940, 941, 943, 944, 957, 959, 960, 1037, 1033, 1063, 1062, 1065, 1068, 1069, 1086.

In another embodiment, the helicobacter pylori outer membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof having a C-terminal tyrosine cluster selected from the group consisting of: 777, 817, 865, 890, 913, 945, 956, 1052, 1063, 1077, 1297 and 1298.

In another embodiment, the helicobacter pylori outer membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof having a terminal phenylalanine residue and a C-terminal tyrosine cluster selected from the group consisting of: 810, 816, 916, 928, 929, 938, 939, 958, 1050, 1081 and 1085 SEQ ID NOs.

In another embodiment, the H.pylori envelope polypeptide or fragment thereof is a H.pylori inner membrane polypeptide or fragment thereof selected from the group consisting of SEQ ID NO 845, SEQ ID NO 863, SEQ ID NO 891, SEQ ID NO 912, SEQ ID NO 1076, SEQ ID NO 954, SEQ ID NO 772, SEQ ID NO 1042, SEQ ID N0:902, SEQ ID NO 898, SEQ ID NO 1071, SEQ ID NO 781, SEQ ID NO 908, SEQ ID NO 921, SEQ ID NO 1046 and SEQ ID NO 1079.

In another embodiment, the H.pylori inner membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof involved in outer membrane and cell wall synthesis comprising the amino acid sequence of SEQ ID NO: 845.

In another embodiment, the helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in energy conversion selected from the group consisting of: 863, 891, 912 and 1076.

In another embodiment, the H.pylori inner membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof involved in cofactor metabolism comprising the amino acid sequence of SEQ ID NO: 954.

In another embodiment, the H.pylori inner membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof involved in secretion or adhesion selected from the group consisting of SEQ ID NO 772 and SEQ ID NO 1042.

In another embodiment, the H.pylori inner membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof involved in transport selected from SEQ ID NO:898 and SEQ ID NO: 1071.

In another embodiment, the H.pylori cell envelope polypeptide or fragment thereof is a H.pylori flagella polypeptide or fragment thereof comprising the amino acid sequence of SEQ ID NO: 968.

In another embodiment, the H.pylori cell envelope polypeptide or fragment thereof is a H.pylori-transporting polypeptide or fragment thereof comprising the amino acid sequence of SEQ ID NO: 905.

Particularly preferred is a pure or isolated helicobacter pylori cytoplasmic polypeptide or fragment thereof, wherein the polypeptide is selected from the group consisting of SEQ ID NO 961, SEQ ID NO 1987, SEQ ID NO 848, SEQ ID NO 948, SEQ ID NO 952, SEQ ID NO 1084, SEQ ID NO 836, SEQ ID NO 874, SEQ ID NO 878, SEQ ID NO 946, SEQ ID NO 1057, SEQ ID NO 842, SEQ ID NO 907, SEQ ID NO 769, SEQ ID NO 826, SEQ ID NO 837, SEQ ID NO 841, SEQ ID NO 910, SEQ ID NO 951, SEQ ID NO 963, SEQ ID NO 105821, SEQ ID NO 1058, SEQ ID NO 1074, SEQ ID NO 1296, SEQ ID NO 809, SEQ ID NO 813, SEQ ID NO 815, SEQ ID NO 838, SEQ ID NO, 931, 937, 955, 981, 982, 1049, 1051, 1059 and 1082.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in energy transfer selected from the group consisting of SEQ ID NO:961 and SEQ ID NO: 1087.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in amino acid metabolism and transport selected from the group consisting of SEQ ID NO:848 and SEQ ID NO: 948.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in nucleotide metabolism and transport selected from the group consisting of SEQ ID NO:952 and SEQ ID NO: 1084.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide involved in cofactor metabolism selected from the group consisting of SEQ ID NO 836, SEQ ID NO 874, SEQ ID NO 878, SEQ ID NO 946 and SEQ ID NO 1057, or a fragment thereof.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in lipid metabolism selected from the group consisting of SEQ ID NO:842 and SEQ ID NO: 907.

In another embodiment, the helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in replication, transcription, recombination and repair of the genome selected from the group consisting of SEQ ID NO 769, SEQ ID NO 826, SEQ ID NO 837, SEQ ID NO 841, SEQ ID NO 910, SEQ ID NO 951, SEQ ID NO 963, SEQ ID NO 1054, SEQ ID NO 1058, SEQ ID NO 1074, and SEQ ID NO 1296.

Particularly preferred is a purified or isolated helicobacter pylori secretory peptide or fragment thereof, wherein the polypeptide is selected from the group consisting of SEQ ID NO 846, SEQ ID NO 1060, SEQ ID NO 748, SEQ ID NO 749, SEQ ID NO 751, SEQ ID NO 752, SEQ ID NO 755, SEQ ID NO 756, SEQ ID NO 759, SEQ ID NO 761, SEQ ID NO 763, SEQ ID NO 765, SEQ ID NO 766, SEQ ID NO 767, SEQ ID NO 770, SEQ ID NO 774, SEQ ID NO 775, SEQ ID NO 778, SEQ ID NO 779, SEQ ID NO 780, SEQ ID NO 782, SEQ ID NO 786, SEQ ID NO 787, SEQ ID NO 788, SEQ ID NO 789, SEQ ID NO 791, SEQ ID NO 792, SEQ ID NO 793, SEQ ID NO 794, 795, 796, 805, 806, 814, 829, 833, 839, 840, 847, 849, 850, 851, 852, 853, 854, 858, 861, 862, 864, 868, 869, 870, 871, 879, 881, 885, 886, 887, 892, 894, 896, 899, 911, 899, SEQ ID NO. 917, SEQ ID NO. 919, SEQ ID NO. 920, SEQ ID NO. 923, SEQ ID NO. 930, SEQ ID NO. 933, SEQ ID NO. 942, SEQ ID NO. 962, SEQ ID NO. 969, SEQ ID NO. 979, SEQ ID NO. 1041, SEQ ID NO. 1044, SEQ ID NO. 1045, SEQ ID NO. 1047, SEQ ID NO. 1055, SEQ ID NO. 1056, SEQ ID NO. 1061, SEQ ID NO. 1067, SEQ ID NO. 1070, SEQ ID NO. 1072, SEQ ID NO. 1075 and SEQ ID NO. 1080.

In another embodiment, the helicobacter pylori secreting polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in secretion and adhesion selected from the group consisting of SEQ ID NO:846 and SEQ ID NO: 1060.

Particularly preferred is a pure or isolated helicobacter pylori cytoplasmic polypeptide or fragment thereof, wherein the polypeptide is selected from the group consisting of SEQ ID NO 747, SEQ ID NO 758, SEQ ID NO 773, SEQ ID NO 797, SEQ ID NO 798, SEQ ID NO 799, SEQ ID NO 800, SEQ ID NO 801, SEQ ID NO 807, SEQ ID NO 808, SEQ ID NO 823, SEQ ID NO 824, SEQ ID NO 827, SEQ ID NO 828, SEQ ID NO 830, SEQ ID NO 831, SEQ ID NO 832, SEQ ID NO 835, SEQ ID NO 860, SEQ ID NO 867, SEQID NO 873, SEQ ID NO 877, SEQ ID NO 914, SEQ ID NO 922, SEQ ID NO 926, SEQ ID NO 927, SEQ ID NO 94949, SEQ ID NO 953, SEQ ID NO 966, SEQ ID NO, 967, 970, 971, 972, 973, 974, 975, 976, 977, 978, 980, 1038, 1048, 1071078 and 1090, respectively.

In another aspect, the invention relates in another aspect to any individual helicobacter pylori polypeptide member of the above-identified helicobacter pylori polypeptide family or a nucleic acid encoding such a member.

In another aspect, the invention features nucleic acids that bind helicobacter pylori mRNA. Such nucleic acids can be used as antisense nucleic acids to control translation of helicobacter pylori mRNA. A further aspect details a nucleic acid which specifically binds to a helicobacter pylori nucleic acid. These nucleic acids are also referred to herein as complementary nucleic acids and can be used as probes and capture reagents.

In another aspect, the invention features an expression system comprising an open reading frame corresponding to a helicobacter pylori nucleic acid. The nucleic acid further contains a control sequence compatible with the desired host. The expression system can be used for preparing polypeptides corresponding to helicobacter pylori nucleic acids.

In another aspect, the invention features cells transformed with the above expression system for the production of a helicobacter pylori polypeptide.

In another aspect, the invention features methods of making antibodies to helicobacter pylori polypeptides that specifically bind to the helicobacter pylori polypeptides. The antibody can be used as an immunoassay reagent for evaluating the content and distribution of helicobacter pylori-specific antigens.

In another aspect, the invention features a method of making a vaccine for the targeted immunization of an individual against helicobacter pylori. The method comprises the following steps: the recipient is immunized with a helicobacter pylori polypeptide, such as a surface or secreted polypeptide or an active ingredient thereof, and a pharmaceutically acceptable carrier. Such vaccines are useful in therapy and prophylaxis.

In another aspect, the invention provides a method of making a vaccine comprising a modified immunogenic helicobacter pylori polypeptide, such as a surface or secreted polypeptide, or an active ingredient thereof, and a pharmaceutically acceptable carrier.

In another aspect, the invention features methods of evaluating the ability of a compound, such as a polypeptide, e.g., a fragment of a host cell polypeptide, to bind to a helicobacter pylori polypeptide. The method comprises the following steps: contacting the test compound with a helicobacter pylori polypeptide and detecting whether the compound binds to or interacts with the helicobacter pylori polypeptide. Compounds which bind to H.pylori are candidate activators or inhibitors of the bacterial life cycle. These assays can be performed in vitro or in vivo.

In another aspect, the invention features methods for evaluating the ability of a compound, such as a polypeptide, e.g., a fragment of a host cell polypeptide, to bind to a helicobacter pylori nucleic acid, e.g., DNA or RNA. The method comprises the following steps: contacting the test compound with a helicobacter pylori nucleic acid and detecting whether the compound binds to or interacts with a helicobacter pylori polypeptide. Compounds which bind to H.pylori are candidate activators or inhibitors of the bacterial life cycle. These assays can be performed in vitro or in vivo.

The present invention features a helicobacter pylori polypeptide, preferably a substantially pure preparation of a helicobacter pylori polypeptide, or a recombinant helicobacter pylori polypeptide. In a preferred embodiment: the polypeptide has biological activity; the polypeptide contains an amino acid sequence which is at least 60%, 70%, 80%, 90%, 95%, 98% or 99% homologous with the amino acid sequence listed in the sequence table; the polypeptide contains an amino acid sequence which is basically the same as the amino acid sequence in the sequence table; a polypeptide is at least 5,10, 20, 50,100, or 150 amino acid residues in length; the polypeptide comprises at least 5, preferably at least 10, more preferably at least 20, even more preferably at least 50,100 or 150 consecutive amino acid residues of the polypeptides of the sequence listing.

In a preferred embodiment, the H.pylori polypeptide is encoded by a nucleic acid contained in the sequence listing or by a nucleic acid which is at least 60%, 70%, 80%, 90%, 95%, 98% or 99% homologous to a nucleic acid as depicted in the sequence listing.

In a preferred embodiment, the H.pylori polypeptide of the invention differs from the sequence listing in 1, 2, 3,5, 10 or more of the amino acid residues of the amino acid sequence. These differences, however, still allow the H.pylori polypeptide to exhibit H.pylori biological activity, e.g., the H.pylori polypeptide retains the biological activity of the naturally occurring H.pylori enzyme.

In a preferred embodiment, the polypeptide comprises all or a fragment of the amino acid sequence contained in the sequence listing; the fusion of additional amino acid residues in reading frame, preferably the residue encoded by genomic DNA 5', is fused to genomic DNA encoding the sequence contained in the sequence listing.

In yet another preferred embodiment, the H.pylori polypeptide is a recombinant fusion protein comprising a first H.pylori polypeptide portion and a second polypeptide portion, such as a polypeptide having an amino acid sequence unrelated to H.pylori, which may be, for example, any one of: glutathione S-transferase, a DNA binding domain or a polymerase activation domain. In a preferred embodiment, the fusion protein is used in a two-hybrid assay.

The polypeptides of the invention include polypeptides produced by variable transcription events, variable RNA splicing events, and variable translation and post-translation events.

The invention also includes an immunogenic composition comprising a helicobacter pylori polypeptide in an immunogenic preparation; the immunogenic component is capable of eliciting an immune response, such as a humoral response, an antibody response or a cellular response, specific for the helicobacter pylori polypeptide. In a preferred embodiment, the immunogenic component comprises at least one antigenic determinant from a polypeptide contained in the sequence listing.

In another aspect, the invention provides substantially pure nucleic acids comprising a nucleotide sequence encoding a helicobacter pylori polypeptide. In a preferred embodiment: the encoded polypeptide has biological activity; the encoded polypeptide contains an amino acid sequence which is at least 60%, 70%, 80%, 90%, 95%, 98% or 99% homologous with the amino acid sequence listed in the sequence table; the encoded polypeptide contains an amino acid sequence which is basically the same as the amino acid sequence in the sequence table; the encoded polypeptide is at least 5,10, 20, 50,100, or 150 amino acid residues in length; the encoded polypeptide comprises at least 5, preferably at least 10, more preferably at least 20, even more preferably at least 50,100 or 150 consecutive amino acid residues of the polypeptides of the sequence listing.

In a more preferred embodiment, a nucleic acid encoding a helicobacter pylori polypeptide of the invention hybridizes under stringent conditions to a probe corresponding to at least 8 contiguous nucleotides of a nucleic acid as set forth in the sequence listing; more preferably to a probe corresponding to at least 12 contiguous nucleotides of a nucleic acid as set forth in the sequence listing; more preferably to a probe corresponding to at least 20 contiguous nucleotides of a nucleic acid as set forth in the sequence listing; more preferably to a probe corresponding to at least 40 contiguous nucleotides of a nucleic acid as set forth in the sequence listing.

In preferred embodiments, the nucleic acid is a nucleic acid as set forth in the sequence listing that is at least 60%, 70%, 80%, 90%, 95%, 98%, or 99% homologous to a nucleic acid as set forth in the sequence listing.

In a preferred embodiment, the encoded H.pylori polypeptide differs from the sequence listing in 1, 2, 3,5, 10 or more of the amino acid residues in the amino acid sequence (e.g., by amino acid substitution, addition or deletion of at least one amino acid residue). However, these differences still allow the encoded H.pylori polypeptide to exhibit H.pylori biological activity, e.g., the encoded H.pylori enzyme retains the biological activity of naturally occurring H.pylori.

In a preferred embodiment, the encoded polypeptide comprises all or a fragment of an amino acid sequence contained in the sequence listing; the fusion of additional amino acid residues in reading frame, preferably the residue encoded by genomic DNA 5', is fused to genomic DNA encoding the sequence contained in the sequence listing.

In a preferred embodiment, the helicobacter pylori nucleic acid of the present invention may comprise a transcription regulatory sequence, such as at least one of a transcription promoter or transcription enhancer sequence, operably linked to the helicobacter pylori gene sequence, such as to render the helicobacter pylori gene sequence suitable for expression in a recombinant host cell.

In a further embodiment, the nucleic acid encodes a peptide that differs from a sequence set forth in the sequence listing by at least one amino acid residue.

In a preferred embodiment, the nucleic acid differs from a nucleotide sequence shown in the sequence listing encoding an amino acid sequence shown in the sequence listing by at least one nucleotide.

In another aspect, the invention comprises: a vector comprising a nucleic acid encoding a helicobacter pylori polypeptide or a helicobacter pylori polypeptide variant as described herein; a host cell transfected with the vector; and methods for producing recombinant helicobacter pylori polypeptides or helicobacter pylori polypeptide variants, comprising culturing the cells, for example in a cell culture medium, and isolating the helicobacter pylori polypeptides or helicobacter pylori polypeptide variants, for example from the cells or the cell culture medium.

In another aspect, the invention features a purified recombinant nucleic acid that is at least 50%, 60%, 70%, 80%, 90%, 95%, 98%, or 99% homologous to a sequence contained in the sequence listing.

The invention also provides probes or primers comprising substantially pure oligonucleotides. The oligonucleotide comprises a nucleotide sequence region which hybridizes under stringent conditions to at least 10 consecutive nucleotides of a sense or antisense sequence contained in the sequence listing or a naturally occurring mutant thereof. In preferred embodiments, the probe or primer further comprises a labeling group attached thereto, which may be, for example, a radioisotope, a fluorescent compound, an enzyme and/or a cofactor for an enzyme. Preferably, the oligonucleotide is at least 10 and less than 20, 30, 50,100 or 150 nucleotides in length.

The invention further provides nucleic acids, e.g., RNA or DNA, encoding the polypeptides of the invention. This includes double stranded nucleic acids as well as single strands, both coding and antisense.

The strain of helicobacter pylori, the genomic sequence of which has been determined, has been deposited at the American Type Culture Collection (ATCC) as the strain HP-J99.

The invention comprises the following steps: allelic variation, natural mutation, induced mutation; proteins encoded by DNA that hybridize under high or low stringency conditions to nucleic acids encoding polypeptides represented in the sequence listing (defined in modern methods of molecular biology, John Wiley&Sons, New York,1989,6.3.1-6.3.6, incorporated herein by reference); and polypeptides capable of being specifically bound by antisera directed against helicobacter pylori polypeptides, in particular by antisera directed against the active site or binding region of helicobacter pylori polypeptides. The invention also includes fragments, preferably biologically active fragments. These and other polypeptides are also referred to herein as helicobacter pylori polypeptide analogs or variants.

Several H.pylori polypeptides of the invention have been tested for putative function, see Table 1.

Accordingly, the use of said H.pylori polypeptide in these defined functions is also within the scope of the present invention.

Furthermore, the present invention includes the identified helicobacter pylori polypeptides shown in table 1 below, including: helicobacter pylori cell envelope protein, helicobacter pylori secretory protein, helicobacter pylori cytoplasmic protein and helicobacter pylori cell protein. Members of these groups were identified using BLAST homology searches and secretion signals or transmembrane protein motifs searches. Polypeptides having significant homology relationships to the polypeptides of Table 1, as reflected by the FASTA comparison of amino acid sequences and the performance in each case in tables 3 to 6 below, are also considered to be classified in the manner of homologs as indicated in Table 1.

TABLE 1

ORF names	nt Seq ID#	aa Seq ID#
			A cell envelope
A.l exterior membrane
			A.1.2 terminal phe residues
01ae12001_24218781_f2_18	255	746
			02ge11622_875260_f3_36	263	754
02gp20706_23632775_f3_32	266	757
			07ap11015_23938312_f3_2	271	762
05ee10816_4103408_f2_11	277	768
			06ap20306_23437632_f3_9	280	771
07ap20216_7227202_f3_10	285	776
			14ap10815_20585777_c1_13	292	783
hp1p14013_11726503_c2_20	294	785
			hp5p15641_2 1698387 c2_20	299	790
02gp20706_16803513_f1_1	311	802
			02gp20706_20365905_f2_8	312	803
02gp20814_3984818_f1_1	313	804
			05ae30220_98S2767_f2_34	321	812
07ep11916_5913592_f3_18	327	818
			09ze10333_22460750_f2_6	329	820
14ap10221_13689381_c3_4	331	882
			06ce20610_1367157_f1_8.aa	353	844
02ge10116_16803513_f2_34	364	855
			02ge10116_36367936_c1_92	366	857
05ce10910_25598277_f3_3	368	859
			06cp11217_4881263_f2_9	375	866
06ep30223_34409437_f3_94	384	875
			06gp71906_970325_c3_190	391	882
07ae10923_24426508_f1_1	392	883
			09cp10224_1062966_c3_61	397	888
09cp10224_1412715_c3_56	398	889
			09cp61003_14562637_c2_93	402	893
09cp61003_24063587_c1_74	404	895
			11ae80818_7952_c1_49	409	900
11ap20714_4960432_c3_97	410	901
			11ap20714_7227202_f3_43.aa	412	903
hp5p15641_12195281_c1_24	427	918
			hp6p10903_4398263_f3_6.aa	433	924
hp6p10903_4398263_f3_6.aa	434	925
			02ae31010_30208317_f1_14	441	932
02cp10615_26573462_c1_45	444	935
			03ae10804_12609533_c1_26	445	936
04ep41903_4101593_f2_10.aa	449	940
			05ep1D815_26570332_c2_99	450	941
05ep10815_4719175_c1_83	452	943
			06cp30603_679218_f2_34	453	944
11ac80818_19632781_c3_57	466	957
			11ap20714_34023312_f3_46	468	959
11ee11408_4977193_c1_41.aa	469	960
			11ae11922_12586675_f2_1	983	1037
07ee11402_2458267_c3_108	985	1039
			11ap20714_7227202_f3_40	989	1043
hp7e10192_25598277_c2_15	1008	1062
			06ep30223_34409437_f2_64	1011	1065
09cp10224_1062966_c1_44	1014	1068
			01ce61016_12931513_c2_106	1015	1069
05ep10815_4719175_c1_115	1029	1083

05ae30220_4977193_c3_198	1032	1086
			A.1.3 non-terminal phe residues
02ae11612_22477267_f2_27	259	750
			A.1.4C terminal tyrosine cluster motif
07ep11916_5273452_c3_31	286	777
			07ce11019_22051291_f1_1	326	817
06cp11217_19720300_f3_11	374	865
			09cp10224_429510_c2_46.aa	399	890
hp4e53394_22864682_c2_86.aa	422	913
			06ep10615_961562_f2_41	454	945
09cp61003_492187_c2_80.aa	465	956
			14gp11423_26803801_f3_7	998	1052
hp4e53394_19720300_c3_98	1009	1063
			hp4e53394_19720300_c3_98	1023	1077
01ce61016_492187_c3_120	1294	1297
			06ep10615_961562_f1_15	1295	1298
A.1.5 terminal phe residue and C-terminal tyrosine cluster
			04ge10816_33726080_c2_29	319	810
06ee10709_21675012_f1_2	325	816
			hp5p15575_33445317_f2_20.aa	425	916
01cp20708_36134808_f2_11	437	928
			02ae31010_12504512_f3_28.aa	438	929
04ep41903_26757937_f3_16	447	938
			04ep41903_26757937_f3_16	448	939
11ae80818_7290627_c2_51	467	958
			13ae10610_35912_f2_3	996	1050
01cp20708_13086002_f3_27	1027	1081
			14cp11908_24218954_c1_68	1031	1085
A.1.6 by homology
			01ae11010_40688_c2_38	254	745
02gp20814_24415958_f3_9	269	760
			09cp11003_5945252_f2_4	328	819
06cp30603_23476568_c2_133.aa	352	843
			09cp61003_5945252_f1_5	406	897
14ee41924_23527267_c3_107	415	906
			07ee11402_10759567_c2_86	1019	1073
A.1.7 other outer Membrane proteins
			06ep10615_9842_f3_46	381	872
06gp10409_3398427_f2_12	389	880
			06ep10615_9842_f3_5	1010	1064
06gp10409_3398427_f2_12	1012	1066
			A.2 inner Membrane
A.2.1 proteins involved in outer Membrane and cell wall Synthesis
			06ep30223_4698838_f2_55	354	845
A.2.2 proteins involved in energy conversion
			06ce20610_4331338_f3_18	372	863
09cp10224_4484718_c1_38	400	891
			hp4e13394_5964452_c2_97	421	912
hp4e13394_15828963_c2_90	1022	1076
			A.2.3 proteins involved in cofactor metabolism
06gp71906_25478192_c1_131	463	954

A.2.4 proteins involved in secretion and adhesion
			06cp30603_23452_c3_80	281	772
09cp10713_23452_c3_195	988	1042
			A.2.5 by homology
11ap20714_5271967_c1_60	411	902
			A.2.6 proteins involved in trafficking
11ae80818_11188791_c3_60	407	898
			14cp11908_25593768_c3_97	1017	1071
A.2.7 other inner Membrane proteins
			13ae10712_14100018_f2_12	290	781
hp1p13939_25397327_f3_22	417	908
			hp5p15870_14350428_f1_1	430	921
06ge20501_14100018_c1_34	992	1046
			05ae30220_14350428_f3_91	1025	1079
A.3 flagellin
			hp4e13394_3368767_c1_80	477	968
A.4 transportan
			14ce31519_15635927_f3_15	414	905
A.5 other cell envelope proteins
			04cp11202_24256567_c3_117	253	744
29ge30321_34157812_f3_10	293	784
			29ge30321_12913562_f1_1	334	825
hp6p10233_12273302_f1_1	343	834
			hp2e10911_24855312_c_69	418	909
hp5p15575_29300311_c1_29	424	915
			02ae31010_5085162_c1_47	443	934
B. Cytoplasmic proteins
			B.1 proteins involved in energy conversion
11ge10308_5256_f2_1	470	961
			11ge10308_24609417_f2_1	1033	1087
B.2 proteins involved in amino acid metabolism and transport
			06ep11917_24803153_c3_24	357	848
06ep11202_4884677_c1_17	457	948
			B.3 proteins involved in nucleic acid metabolism and transport
06ep30223_23476067_c1_119	461	952
			06ep30223_23476067_c1_115	1030	1084
B.4 proteins involved in cofactor metabolism
			07ap11213_35156577_c1-24	345	836
06ep30223_23557202_c2_130	383	874
			06ep30223_5109443_c1_109	387	878
06ep11202_133293_c1_19	455	946
			07ee50709_35156577_f3_80	1003	1057
B.5 proteins involved in lipid metabolism
			hp6e1226_14650278_f3_29	351	842
14ee41924_23834800_f2_32	416	907
			B.6 proteins involved in mRNA translation and ribosome formation
14ee41924_16282067_c1_72	473	964
			07ee11402_19565702_c2_88	1034	1088
"B.7 protein involved in genome replication, transcription, recombination and repair"
			05ee10816_4687651_c1_22	278	769

29ge30321_135253_f2_6	335	826
			07ap80601_976413_f3_9	346	837
14ce21516_85786_f1_1	350	841
			hp2e10911_3349_c1_63	419	910
06ep30223_16512_c3_160	460	951
			14ce61516_1307357_f2_12	472	963
07ee50709_4818967_f2_43	1000	1054
			05ae30220_976413_c3_204	1004	1058
07ee50709_4818967_f2_43	1020	1074
			hp7e10590_13073577_c3_107	1293	1296
B.8 other cytoplasmic proteins
			04ge10816_22086531_f2_10	318	809
05cp21223_4725443_f3_14	322	813
			06ap11119_24426508_f3_26	324	815
12ge1032_4821082_f3_14	330	821
			hp3p10807_189075_f2_4	347	838
02ae31010_2117087_f3_34	440	931
			03ae10804_21698400_c2_32	446	937
06gp71906_25504187_f3_112	464	955
			hp7p10290_35156558_f3_15	490	981
hp7p10290_4351718_f1_6	491	982
			13ae10610_859692_c2_32	995	1049
06ap11119_24426508_f3_27	997	1051
			hp3e11188_47327_f2_9	1005	1059
07ee50709_26438968_f2_36	1028	1082
			C.SECRETED PROTEINS
C.1 proteins involved in secretion and adhesion
			12ap10324_4805318_f2_3	355	846
12ap10324_4805318_f2_6	1006	1060
			C.2 other secreted proteins
01gp11016_4103403_c2_13	257	748
			02ae11612_1074212_fl_1	258	749
02ae11612_23598175_f1_2	260	751
			02ae11612_33203250_c1_51	261	752
02gp20706_1203402_c3_58	264	755
			02gp20706_15781452_c2_51	265	756
02gp20706_4892558_f3_19	268	759
			04cp11202_24261588_f2_23	270	761
05ae30220_21619067_f3_56	272	763
			07ap11213_35401528_c1_21	273	764
05ae30220_24882812_c3_103	274	765
			05ac30220_25953163_c3_98	275	766
05ee10816_14649077_f3_18	276	767
			06ap11119_16594193_f1_9	279	770
06cp30603_4689068_c3_79	283	774
			07ap11111_234693_c3_14	284	775
09cp11003_19532625_c3_17	287	778
			09cp20502_24001388_c1_31	288	779
12gp31106_3024126_f2_25	289	780
			13ae10712_29569208_c2_27	291	782
hp2p10272_23697200_f3_22	295	786
			hp2p10272_26829136_f1_1	296	787

hp5e15211_819455_c2_24	297	788
			hp5p15212_34064750_f2_9	298	789
hp6e10967_23476502_f2_6	300	791
			hp6e10967_24882750_f2_7	301	792
hp6e12267_4876718_f2_23	302	793
			hp6e20339_1190660_c2_46	303	794
hp6e20339_21492187_c1_40	304	795
			hp6e20339_34024187_c1_37	305	796
04cp11202_16603425_c2_72	314	805
			04cp11202_19797128_f1_5	315	806
05ee10816_259703_f2_7	323	814
			hp2p10272_22692325_f3_21	338	829
hp6e20339_2431 7062_c3_57	342	833
			02ge11622_21695936_c1_54	348	839
12ge10321_24308513_f3_20	349	840
			14ee41924_2458267_c2_93	356	847
01ce11104_36125337_c1_8	358	849
			01ce21104_33203250_c3_87	359	850
02ae31010_34616666_f2_27	360	851
			02ae31010_35270000_f3_33	361	852
02ae31010_36132785_f2_29	362	853
			02ge10116_15781452_c1_87	363	854
03ae10804_23485968_c3_47	367	858
			06ce20610_29298537_c2_32	370	861
06ce20610_3913967_c3_36	371	862
			06cp11118_212827_c1_17	373	864
06cp30603_21492187_f2_41	377	868
			06cp30603_34024187_f1_20	378	869
06cp30603_34024187_fl_20	379	870
			06ep10615_14649077_f3_52	380	871
06ep30223_5271902_c1_106	388	879
			06gp71906_24261588_c2_174	390	881
09ce10413_414011_fl_3	394	885
			09ce10413_5865665_f1_4	395	886
09ce52017_29324062_c1_21	396	887
			09cp21607_7224187_c2_12	401	892
09cp61003_19532625_c1_78	403	894
			09cp61003_24335762_c3_111	405	896
11ae80818_783127_c3_63	408	899
			hp4e13394_35957200_f1_21	420	911
hp5p15575_6140713_f2_18	426	917
			hp5p15641_24304527_c3_35	428	919
hp5p15641_25635452_c3_34	429	920
			hp6p10606_19546933_c3_31	432	923
02ae31010_16833312_f2_19	439	930
			02ae31010_36132785_f2_29	442	933
05ep10815_4195292_c1_84	451	942
			12ap10324_13178562_f3_6	471	962
hp2e10911_4882027_c2_87	474	965
			hp5p15212_6928132_c3_34	478	969
hp7p10290_25548812_f3_14	488	979
			07ee50709_10213593_f3_77	986	1000

06ep10615_14649077_f2_30	987	1041
			01ce61016_23609580_c3_139	990	1044
06gp71906_3024126_c1_128	991	1045
			09cp10713_34024187_f1_31	993	1047
02ap11117_23495187_c3_81	1001	1055
			09cp10713_34024187_f1_31	1002	1056
hp1e80523_23485968_c2_49	1007	1061
			09ce10413_5865665_f1_4	1013	1067
01ce61016_23609580_c3_139	1016	1070
			14cp11908_783127_c1_72	1018	1072
hp4e13394_5088562_f3_54	1021	1075
			hp8e10080_19546933_c2_88	1026	1080
07ee50709_960952_f2_47	1035	1089
			D. Other cellular proteins
01ge11619_23711062_c3_14	256	747
			02gp20706_23866562_c2_53	267	758
06cp30603_23476568_c1_44	282	773
			01ge10203_35281542_c3_16	306	797
01ge10203_860166_f3_9	307	798
			01ge11619_13788141_c2_11	308	799
01ge11619_24415880_c2_12	309	800
			01ge11619_24417813_c1_8	310	801
04cp11202_23553177_c1_75	316	807
			04cp11202_23553177_c3_109	317	808
29ep10720_24220926_f2_8	332	823
			29ep10720_24432762_c3_39	333	824
29ge30321_21673965_f2_7	336	827
			29ge30321_24336712_f1_5	337	828
hp2p10272_24406280_c1_26	339	830
			hp3p10807_29343768_f1_1	340	831
hp3p10807_29352212_f2_5	341	832
			02ep20506_24611325_f2_6	344	835
06ae11016_30579712_f2_21	369	860
			06cp11 217_4897077_f1_6	376	867
06ep11202_26353438_c1_22	382	873
			06ep30223_4876077_c3_149	386	877
hp5e15044_4554652_f3_3	423	914
			hp6p10590_23440913_c2_31	431	922
hp6p10904_2214676_c1_14	435	926
			hp6p10904_23704412_f2_5	436	927
06ep11202_792962_c2_26.aa	458	949
			06gp71906_15115637_f2_59	462	953
hp3e11188_47327_f2_5	475	966
			hp3e11188_5082842_f3_12	476	967
hp5p15641_30273312_c2_28	479	970
			hp5p15641_5211687_c2_29	480	971
hp6p10590_30521093_f2_14	481	972
			hp6p10904_7089062_c1_16	482	973
hp6p12129_16603417_f3_14	483	974
			hp6p12244_3948467_c1_52	484	975
hp6p22217_23470967_f1_4	485	976
			hp7e10192 4412568_f2_5	486	977

hp7p10287_24611325_c2_24	487	978
			hp7p10290_25585941_f3_12	489	980
02ge10116_23866562_c3_146	984	1038
			hp4p62853_5914693_c3_52	994	1048
07ce10312_4554652_f3_2	1024	1078
			hp6p12244_3948467_c3_88	1036	1090

(in Table 1, "nt" represents the nucleotide seq. ID No.; and "aa" represents the amino acid seq. ID No.)

Defining:

as used herein, a pure or substantially pure preparation of a polypeptide means that the polypeptide has been isolated from other proteins, lipids, and nucleic acids with which it naturally occurs. Preferably, the polypeptide is also isolated from the substance used to purify it, such as an antibody, or a gel matrix, such as polyacrylamide. Preferably, the polypeptide constitutes at least 10, 20, 50, 70, 80 or 95% of the dry weight of the pure preparation. Preferably, the preparation comprises: a polypeptide sufficient for protein sequencing; at least 1,10 or 100ug of polypeptide; at least 1,10 or 100mg of polypeptide.

A pure preparation of cells, in the case of plant or animal cells, refers to an in vitro preparation of cells rather than whole plants or animals; by cultured cells or microbial cells is meant that the preparation contains at least 10% and more preferably 50% of the cells of interest.

Substantially pure nucleic acids, such as substantially pure DNA, are one or both of the following: not immediately adjacent to the coding sequences that are immediately adjacent to both ends (i.e., one at the 5 'end and the other at the 3' end) in the genome that naturally occurs in the organism from which the nucleic acid is obtained; or substantially free of nucleic acids present in the organism from which the nucleic acids were obtained. The word includes: for example, recombinant DNA that is integrated into a vector such as an autonomously replicating plasmid or virus or into the genomic DNA of a eukaryote or prokaryote, or recombinant DNA that exists as a separate molecule(e.g., a cDNA or genomic DNA fragment produced by PCR or restriction endonuclease treatment) independent of other DNA sequences. The substantially pure DNA also includes recombinant DNA which is part of a hybrid gene encoding additional H.pylori DNA sequences.

As used herein, a "contig" is a contiguous segment of genomic sequence representing an organism.

An "open reading frame," also referred to herein as an ORF, is a region of nucleic acid that encodes a polypeptide. The region may represent a portion of the coding sequence or the entire sequence.

A "coding sequence" is herein a nucleic acid capable of being transcribed into messenger RNA and/or translated into a polypeptide when placed under the control of appropriate regulatory sequences. The boundaries of the coding sequence are determined by a translation start codon at the 5 'primer end and a translation stop codon at the 3' primer end. Coding sequences may include, but are not limited to, messenger RNA, synthetic DNA, and recombinant nucleic acid sequences.

As used herein, the "complementary component" of a nucleic acid refers to an antiparallel or antisense sequence that participates in Watson-Crick base pairing with the original sequence.

A "gene product" is a protein or structural RNA that is specifically encoded by a gene.

As used herein, the term "probe" is a nucleic acid, peptide, or other chemical entity that specifically binds to a molecule of interest. The probe is typically or can be linked to a label. Labels are chemical moieties that can be detected. Typical labels include dyes, radioisotopes, luminescent or chemiluminescent moieties, fluorescers, enzymes, agglutinating agents, amplification sequences, and the like. Similarly, nucleic acids, peptides or other chemical entities that specifically bind to and immobilize a molecule of interest are referred to herein as "capture ligands". The capture ligand is typically attached or capable of being attached to a matrix such as nitrocellulose, glass, nylon membranes, beads, particles. The specificity of hybridization depends on conditions such as the base composition of nucleotides, the temperature of the reaction, and the salt concentration. These conditions can be readily determined by one of ordinary skill in the art using routine experimentation.

Homologous means that the sequences between two polypeptides or two nucleic acid molecules are similar or equivalent. When the same position of two compared sequences is occupied by the same base or amino acid monomer subunit, e.g., if one position of both DNA molecules is occupied by an adenylate, then the two molecules are homologous at that position. The percent homology of two sequences is the number of positions at which the two sequences match or are homologous divided by the number of positions compared x 100. For example, if there are 6 matches or homologies in 10 positions of two sequences, then the two sequences are 60% homologous. For example, the DNA sequences ATTGCC and TATGGC are 50% homologous. Generally, two sequences are compared in such a way that they are aligned to give the greatest homology.

Nucleic acids can hybridize to each other when at least one strand of the nucleic acid can anneal to another nucleic acid under defined stringency conditions. Stringency of hybridization was determined as follows: (a) the temperature at which hybridization and/or washing is carried out; and (b) the ionic strength and polarity of the hybridization and wash solutions. Hybridization requires that the two nucleic acids contain complementary sequences, but mismatches can be tolerated depending on the stringency of the hybridization. In general, it is desirable that the sequences be substantially fully homologous when the two sequences hybridize underhighly stringent conditions (e.g., in a 0.5 XSSC solution at 65 ℃). Less full complementarity is required between hybridizing sequences under conditions of moderate stringency (e.g., 2 XSSC, 65 ℃) or low stringency (e.g., 2 XSSC, 65 ℃). (1 XSSC is 0.15M) 0.015M sodium citrate).

The terms peptide, protein, polypeptide, and the like are used generically herein.

As used herein, the term "surface protein" refers to all proteins that can reach the surface, such as inner and outer membrane proteins, proteins that adhere to the cell wall, and secreted proteins.

A polypeptide has helicobacter pylori biological activity if it contains one, two and preferably more of the following properties: (1) when it is expressed during H.pylori infection, it promotes or mediates the adhesion of H.pylori to the cells; (2) it has the enzymatic activity characteristic of helicobacter pylori protein; (3) or the gene encoding it is capable of rescuing a lethal mutation of the helicobacter pylori gene. A polypeptide is biologically active if it is an antagonist, agonist or superagonist of a polypeptide having the above characteristics.

Biologically active fragments or analogs are those having in vivo or in vitro activity which is characteristic of a H.pylori polypeptide as shown in the sequence listing or other naturally occurring H.pylori polypeptide, such as one or more of the biological activities described herein. Particularly preferred are fragments which are present in vivo, for example fragments resulting from post-transcriptional processing or from translation of alternatively spliced RNA. These fragments include fragments expressed in natural or endogenous cells as well as those produced in expression systems such as CHO cells. Since peptides such as H.pylori polypeptides generally exhibita wide range of physiological activities and since these characteristics can be attributed to different parts of the molecule, useful H.pylori polypeptide fragments or H.pylori analogs are those that are capable of exhibiting biological activity in any H.pylori biological activity assay. Most preferred fragments or analogues have a helicobacter pylori activity of 10%, preferably 40%, more preferably 90% or more in an in vivo or in vitro assay.

The analog may differ from the naturally occurring H.pylori polypeptide by either the amino acid sequence or by a way that does not involve the sequence, or both. Non-sequence modifications include acetylation, formylation, phosphorylation, carboxylation, or glycosylation changes. Preferred analogs include those helicobacter pylori polypeptides (or biologically active fragments thereof) having one or more conservative or non-conservative amino acid substitutions, deletions, or insertions, as compared to the wild-type sequence, which do not substantially eliminate the biological activity of the helicobacter pylori polypeptide. Conservative substitutions typically include the substitution of one amino acid for another with similar characteristics, for example in the following groups: valine, glycine; glycine, alanine; valine, isoleucine, leucine; aspartic acid, glutamic acid; asparagine, glutamine; serine, threonine; lysine, arginine; and phenylalanine, tyrosine. Other conservative substitutions are summarized in table 2 below.

TABLE 2

Conservative amino acid substitutions

Amino acids	Code	By replacing with any one
			Alanine	A	D-Ala,Gly,beta-Ala,L-Cys,D-Cys
Arginine	R	D-Arg,Lys,D-Lys,homo-Arg,D-homo-Arg,Met,Ile,D-Met,D-Ile,Orn, D-Orn
			Asparagine	N	D-Asn,Asp,D-Asp,Glu,D-Glu,Gln,D-Gln
Aspartic acid	D	D-Asp,D-Asn,Asn,Glu,D-Glu,Gln,D-Gln
			Cysteine	C	D-Cys,S-Me-Cys,Met,D-Met,Thr,D-Thr
Glutamine	Q	D-Gln,Asn,D-Asn,Glu,D-Glu,Asp,D-Asp
			Glutamic acid	E	D-Glu,D-Asp,Asp,Asn,D-Asn,Gln,D-Gln
Glycine	G	Ala,D-Ala,Pro,D-Pro,β-Ala,Acp
			Isoleucine	I	D-Ile,Val,D-Val,Leu,D-Leu,Met,D-Met
Leucine	L	D-Leu,Val,D-Val,Leu,D-Leu,Met,D-Met
			Lysine	K	D-Lys,Arg,D-Arg,homo-Arg,D-homo-Arg,Met,D-Met,Ile,D-Ile,Orn, D-Orn
Methionine	M	D-Met,S-Me-Cys,Ile,D-lle,Leu,D-Leu,Val,D-Val
			Phenylalanine	F	D-Phe,Tyr,D-Thr,L-Dopa,His,D-His,Trp,D-Trp,Trans-3,4,or 5-phenylproline,cis-3,4,or 5-phenylprolinc
Proline	P	D-Pro,L-I-thioazolidine-4-carboxylic acid,D-or L-1-oxazolidine-4- carboxylic acid
			Serine	S	D-Ser,Thr,D-Thr,allo-Thr,Met,D-Met,Met(O),D-Met(O),L-Cys,D-Cys
Threonine	T	D-Thr,Ser,D-Ser,allo-Thr,Met,D-Met,Met(O),D-Met(O),Val,D-Val
			Tyrosine	Y	D-Tyr,Phe,D-Phe,L-Dopa,His,D-His
Valine	V	D-Val,Leu,D-Leu,Ile,D-Ile,Met,D-Met

Other analogs of the invention are those with modifications that increase polypeptide stability, such analogs may contain, for example, one or more non-peptide bonds (in place of peptide bonds) in the polypeptide sequence, and also include analogs containing L amino acids that are not naturally occurring, such as D-amino acids, or non-naturally occurring or synthetic amino acids, such as β or gamma amino acid residues, and cyclic analogs.

As used herein, the term "fragment" when used in reference to H.pylori analogs generally has a length of at least about 20 residues, more typically at least about 40 residues, and preferably at least about 60 residues. Fragments of helicobacter pylori polypeptides can be prepared by methods well known to those skilled in the art. The ability of the test fragment to exhibit the biological activity of a H.pylori polypeptide can be assessed by methods well known to those skilled in the art as described herein. Also included are: helicobacter pylori polypeptides that contain residues that are not required for the biological activity of the peptide or that result from alternative mRNA splicing or alternative protein processing events.

"immunogenic component" as used herein refers to a moiety capable of eliciting a humoral and/or cellular immune response in a host animal, such as a helicobacter pylori polypeptide, an analogue or fragment thereof.

An "antigenic component" as used herein is a moiety capable of binding to a specific antibody with sufficiently high affinity to form a detectable antigen-antibody complex, such as a helicobacter pylori polypeptide, an analog or fragment thereof.

As used herein, the term "transgenic" means that a nucleic acid is partially or completely heterologous, i.e., foreign, to the transgenic animal or cell into which it is introduced; or homologous to an endogenous gene of the transgenic animal or cell into which it is introduced, but which is designed to be inserted, or inserted into the genome of the cell, in a manner that alters the genome of the cell into which it is inserted (e.g., it is inserted at a different location than the original gene or its insertion results in a knockout). A transgene may contain one or more transcription regulatory sequences as well as any other nucleic acids, such as introns. These sequences and nucleic acids are necessary for optimal expression of the selected nucleic acid, and are all operably linked to the selected nucleic acid; the transgene may also contain enhancer sequences.

As used herein, the term "transgenic cell" refers to a cell that contains a transgene.

As used herein, a "transgenic animal" is any animal whose one or more, and preferably substantially all, of its cells contain a transgene. Transgenes may be introduced into cells by means of a direct or indirect introduction into a precursor of the cell by purposeful genetic manipulation, e.g., by microinjection or infection with a recombinant virus. This molecule may be integrated into the chromosome, or it may be an extrachromosomally replicating DNA.

The term "antibody" as used herein is intended to include fragments which specifically react with helicobacter pylori polypeptides.

As used herein, the term "cell-specific promoter" means a DNA sequence that can be used as a promoter, i.e., to regulate the expression of a selected DNA sequence operatively linked to the promoter, as well as to affect the expression of the selected DNA sequence in a particular tissue cell. The term also covers so-called "leaky" promoters which regulate expression of the selected DNA primarily in one tissue but can cause expression in other tissues as well.

Misexpression, as used herein, refers to a non-wild type pattern of gene expression. It includes: expression at a non-wild type level, i.e., over or under expression; an expression pattern that differs from the wild type with respect to time or stage of gene expression, e.g., increased or decreased expression (as compared to the wild type) at a predetermined developmental stage or stage; an expression pattern different from wild type with respect to reduced expression (compared to wild type) in a predetermined cell type or tissue type; an expression pattern that differs from the wild type with respect to the size of the spliceosome, the amino acid sequence, the post-transport modification, or the biological activity of the expressed polypeptide; the expression pattern differs from that of the wild type with respect to the effect of environmental or extracellular stimuli on gene expression, e.g., an increased or decreased (compared to the wild type) expression pattern in the presence of an increased or decreased intensity of the stimulus.

As used herein, "host cell" and other words that refer to a microorganism or higher eukaryote cell line cultured as a single cell entity refer to cells that can be, or have been, used as recipients for recombinant vectors or other transfer DNA, and include progeny of the original cell that is transfected. It will be appreciated by those skilled in the art that the progeny of a single parent cell need not be identical or identical in DNA to the genome of the original parent, due to accidental or deliberate mutation.

As used herein, the term "control sequence" refers to a nucleic acid comprising a base sequence recognized by a host organism to affect the expression of a coding sequence associated therewith. The nature of such regulatory sequences varies from host organism to host organism; in prokaryotes, such regulatory sequences typically include a promoter, ribosome binding site, and terminator; in eukaryotes, such regulatory sequences typically include promoters, terminators, and, in some cases, enhancers. Regulatory sequences include, at a minimum, all components whose presence is essential for expression, and may include additional components whose presence is beneficial, such as leader sequences.

As used herein, "operably linked" refers to a combination or linkage of sequences in a manner that enables a desired function. For example, a regulatory sequence is operably linked to a coding sequence; the linkage is such that expression of the coding sequence is successful in an environment compatible with the regulatory sequences and the host.

As used herein, the metabolism of a substance means any aspect of the expression, function, effect or regulation of the substance. Metabolism of a substance includes modifications, such as covalent or non-covalent modification of the substance. Metabolism of a substance includes modification, such as covalent or non-covalent modification. This substance is induced among others. Metabolism of a substance also includes changes in the distribution of the substance. Metabolism of a substance includes the substance inducing a change in the distribution of other substances.

"sample" as used herein refers to a biological sample such as, for example, tissue or fluid isolated from an individual (including but not limited to plasma, serum, cerebrospinal fluid, lymph, tears, saliva, and tissue sections) or from in vitro cell cultures, as well as samples isolated from the environment.

The practice of the present invention will employ, unless otherwise indicated, conventional techniques of biochemistry, molecular biology, microbiology, recombinant DNA, and immunology, which are within the skill of the art. These techniques have been described in detail in the literature, see for example Sambrook, Gritsch and Maniatis molecular cloning: laboratory guidelines, 2 nd edition (1989); DNA cloning, volumes I and II (D.N. Glover eds., 1985); oligonucleotide synthesis (eds. M.J.Gait, 1984) nucleic acid hybridization (B.D.Hames&S.J.Higgins, 1984); methods in enzymology series (Academic Press, Inc), in particular volumes 154 and 155 (Wu and Crossman eds.) and entry to PCR operations (McPherson, Quirke and Taylor eds., 1991).

I isolation of helicobacter pylori nucleic acids and uses thereof

Helicobacter pylori genomic sequence

The present invention provides nucleotide sequences of the H.pylori genome, thus a library of DNA sequences comprising H.pylori genomic DNA. The following detailed description provides the nucleotide sequences of H.pylori and also describes how these sequences are obtained and how the ORFs and protein coding sequences are determined. Methods of use of the disclosed helicobacter pylori sequences, including diagnostic and therapeutic applications, are also described. Furthermore, the library can be used as a database to identify and compare medically important sequences of this or other H.pylori strains.

To determine the genomic sequence of H.pylori, DNA was isolated from a strain of H.pylori and mechanically sheared to a medium size of 2kb by nebulisation, size fractionated by gel electrophoresis, the fragments were blunt-ended, ligated with adaptor oligonucleotides and cloned into 20 different pMPX vectors (Rice et al, summary of genome map and sequencing conference, Cold spring harbor, NY, pages 5/11-5/15,1994,225) to construct a series of "shotgun" subclone libraries.

DNA sequencing is accomplished using a multiplex sequencing method essentially as disclosed in Church et al 1988, science 240, page 185, U.S. Pat. Nos. 4,942,124 and 5,149,625. DNA is extracted from the mixed culture and chemically or enzymatically sequenced, the sequencing reactions are separated electrophoretically, and the product is transferred and covalently attached to a nylon membrane. Finally, the membrane is hybridized with a series of labeled oligonucleotides that are complementary to "tag" sequences present in different shotgun cloning vectors. In this way, a large number of sequences can be obtained from a single set of sequencing reactions. Cloning and sequencing methods are described in more detail in the examples.

Individual sequences read in this way were used with FALCON^TMThe program (church et al, 1994, "automated DNA sequencing and analysis", edited by J.C. vendor, Academic Press) and PHRAP (P.Green, Abstract of DOE Human Genome ProgrammConractor-Grante Workshop V,1 month 1996, page 157) were arranged. The resulting collection of contigs each represents a contiguous stretch of DNA or DNA sequence. The average length of the contig was about 3 kb.

Different methods can be used to order contigs to obtain a contiguous sequence representing the entire H.pylori genome. Artificially synthesized oligonucleotides complementary to the sequences at the ends of each contig were designed. These oligonucleotides are hybridized with a H.pylori genomic DNA library, such as in a lambda phage vector or in a plasmid vector, to determine clones containing sequences corresponding to the junction regions of the different contigs. These clones were then used as isolated template DNA and the same oligonucleotides were used as primers to amplify the ligated fragments by Polymerase Chain Reaction (PCR) and then to determine their nucleotide sequences.

The helicobacter pylori sequence is analyzed for the presence of Open Reading Frames (ORFs) containing at least 180 nucleotides. An ORF of at least 180 nucleotides (based on stop codon-stop codon reading) is predicted. As a result of the analysis of ORFs based on stop codon-stop codon reading, it will be understood that these ORFs may not correspond to the ORF of a naturally occurring H.pylori polypeptide. These ORFs may contain an initiation codon which represents the initiation of synthesis of a naturally occurring H.pylori polypeptide protein. The initiation codons in these ORFs provided herein can be determined by one of ordinary skill in the relevant art, and the obtained ORFs and the encoded H.pylori polypeptides are also within the scope of the present inventionAnd (4) the following steps. For example, in ORFs, a codon such as AUG or GUG (encoding methionine or valine), which is part of the initiation signal for protein synthesis, can be determined and the ORF can be modified to correspond to a naturally occurring H.pylori polypeptide. By using the program GENEMARK^TM(Borodovsky and McInich,1993, Comp. chem. 17, p 123) the coding ability of these sequences was evaluated to determine the expected coding region.

Other helicobacter pylori nucleic acids

The nucleic acid of the present invention can be obtained from the DNA of the above-mentioned helicobacter pylori strain by using Polymerase Chain Reaction (PCR). For details on PCR, see "entry to PCR manipulation" (McPherson, Quirke and Tayor, published by IRL, Oxford, UK, 1991). High fidelity PCR can be used to ensure faithful DNA copies prior to expression. In addition, the amplification products can be detected using conventional sequencing methods. Clones carrying the desired sequences described in the present invention can be obtained by screening libraries by PCR methods well known in the art, or by hybridization of synthetic oligonucleotide probes to library clones or filters covered by phages (see, for example, Sambrook, Gritsch and Maniatis molecular cloning: A laboratory Manual, 2 nd edition (1989) Cold spring harbor Press, NY).

Nucleic acids encoding H.pylori polypeptides can also be obtained from cDNA libraries according to the methods described herein. The cDNA encoding the H.pylori polypeptide can be obtained by isolating the entire mRNA from an appropriate cell line. Double-stranded cDNA can be obtained from mRNA. The cDNA can then be inserted into an appropriate plasmid or viral (e.g., bacteriophage) vector using any of a variety of known techniques. The gene encoding the H.pylori polypeptide can also be cloned using the polymerase chain reaction established on the basis of the nucleic acid sequence information provided by the present invention. The nucleic acid of the present invention may be DNA or RNA, and preferred nucleic acids are shown in the sequence listing.

The nucleic acids of the invention may also be chemically synthesized using standard techniques. A variety of methods for chemically synthesizing polydeoxyribonucleotides are known, including solid phase synthesis, which, like peptide synthesis, is entirely automated ona commercially available DNA synthesizer (see, e.g., Itakura et al, U.S. Pat. No.4,598,049; Caruther et al, U.S. Pat. No.4,458,066 and Itakura et al, U.S. Pat. Nos. 4,401,796 and 4,373,071, incorporated herein by reference).

Isolated or synthetic nucleic acids according to features of the invention can be used as expression systems such as, but not limited to, probes, primers, capture ligands, antisense genes, and for the development of protein and peptide synthesis corresponding to these sequences. As probes, primers, capture ligands, antisense agents, these nucleic acids are generally composed of all or part of the nucleic acids shown in the sequence listing (about 20 or more nucleotides for specificity and formation of stable hybridization products).

These applications are described in more detail below.

Probe needle

An isolated or synthetic nucleic acid based on the nucleotide sequence listed in the sequence listing can be used as a probe for specifically detecting helicobacter pylori. Using the sequence information set forth in this application, sequences of 20 or more nucleotides can be identified that provide the desired information of inclusion and exclusion with respect to H.pylori, as well as foreign nucleic acids that may be encountered in a hybridization environment. More preferably, the sequence contains at least 20 to 30 nucleotides to provide stability to the hybridization product formed between the probe and the desired target molecule.

Sequences greater than 100 nucleotides in length are difficult to synthesize, but can be produced by recombinant DNA techniques. It will be readily understood by those skilled in the art that the nucleic acid used as a probe may carry a label to facilitate detection of the hybridization product.

Isolated or synthetic nucleic acids according to the sequence listing may also be used as probes to detect homologous regions (particularly homologous genes) of other helicobacter species using appropriately stringent hybridization conditions as described herein.

Capture ligands

For use as capture ligands, the nucleic acids selected by the methods described above with respect to the probes can be readily attached to a support. Methods for attaching nucleic acids to supports are well known. Nucleic acids containing 20 or more nucleotides of the sequences contained in the sequence listing can be used to separate helicobacter pylori nucleic acids from each other and from other organisms. Nucleic acids containing 20 or more nucleotides of the sequences shown in the sequence listing can also be used to separate other helicobacter species from each other and from other organisms. Preferably, the sequence should comprise at least 20 nucleotides to stabilize the hybridization product formed between the probe and the desired target molecule. Sequences greater than 1000 nucleotides in length are difficult to synthesize, but can be prepared using recombinant DNA techniques.

Primer and method for producing the same

Isolated or synthetic nucleic acids according to the sequences described herein can be used as primers for the amplification of helicobacter pylori nucleic acids. These nucleic acids can also be used as primers to amplify nucleic acids from other helicobacter pylori species. With respect to Polymerase Chain Reaction (PCR) techniques, nucleic acids containing nucleotides 10-15 or more of the sequence listing may be used with appropriate enzymes and reagents to generate copies of H.pylori nucleic acids. More preferably, the sequence should comprise at least 20 or more nucleotides to stabilize the hybridization product formed between the primer and the desired target molecule. The binding conditions for obtaining specificity for primers greater than 100 nucleotides are difficult to control. High fidelity PCR can be used to ensure that faithful DNA copies are obtained prior to expression. In addition, the amplification products can be detected using conventional sequencing methods.

The copies may be used in diagnostic assays to detect specific sequences, including genes from helicobacter pylori and/or other helicobacter species. The copies may also be incorporated into cloning and expression vectors to prepare polypeptides corresponding to the nucleic acids synthesized by PCR, as described in more detail herein.

Antisense gene

Isolated or synthetic nucleic acids or nucleic acid hybrid derivatives according to the sequences described herein can be used as antisense agents to block the expression of the H.pylori gene. These sequences may also be used as antisense agents to block the expression of other helicobacter species genes.

In one embodiment, the nucleic acid or derivative corresponding to helicobacter pylori nucleic acid is loaded into a suitable carrier such as a liposome or phage for introduction into the bacterial cell. For example, a nucleic acid containing 20 or more nucleotides can bind to a bacterial nucleic acid or a bacterial messenger RNA. Preferably, the antisense nucleic acid comprises 20 or more nucleotides to stabilize the hybridization product of the non-naturally occurring nucleic acid with the bacterial nucleic acid and/or bacterial messenger RNA. Nucleic acids having a sequence length greater than 1000 nucleotides are difficult to synthesize, but can be prepared using recombinant DNA techniques. Methods for loading antisense nucleic acids into liposomes are well known in the art, for example, U.S. Pat. No. 12/23 1980 to Papapapaahadjopoulos et al. 4,241,046.

II expression of helicobacter pylori nucleic acids

Isolated or synthetic nucleic acids according to the sequences described herein can be used to prepare polypeptides. The nucleic acids mentioned in the sequence listing encoding the helicobacter pylori active part or fragments of said nucleic acids can be cloned into suitable vectors or used for isolating the nucleic acids. The isolated nucleic acid is ligated with an appropriate DNA linker and cloned into an appropriate vector.

The function of a particular gene or operon can be identified by expression in a bacterial strain under conditions where the particular gene product of the gene or operon in question can be specifically detected.

In order to express the gene product using the natural helicobacter pylori promoter, a method such as the following can be used. The restriction fragment containing the gene of interest and its associated native promoter elements and regulatory sequences (as determined by the DNA sequence data) is cloned into an appropriate recombinant plasmid containing a replication initiation site and appropriate selectable markers that function in the host organism. This can be accomplished by a variety of methods well known to those skilled in the art. The most preferred method is to cleave the plasmid and the fragment to be cloned is also cleaved with the same enzyme to produce matching ends which are able to join the two fragments together by ligation. The recombinant plasmid is introduced into a host organism, for example by electroporation, and cells containing the recombinant plasmid are identified by screening for the marker on the plasmid. Expression of the desired gene product is detected using assays specific for the gene product.

Where a gene requires a different promoter, the entity (coding sequence) of the gene is specifically cleaved and cloned into an appropriate expression plasmid, and this subcloning can be performed by several methods, but the most readily accomplished method is PCR amplification of the specific fragment, followed by ligation into an expression vector after treatment with restriction enzymes or exonucleases to generate ends suitable for cloning.

The host cell suitable for gene expression may be any prokaryotic or eukaryotic cell. For example, a helicobacter pylori polypeptide can be expressed in bacteria such as E.coli cells, insect cells (baculoviruses), yeast, or mammalian cells such as Chinese hamster ovary Cells (CHO). Other suitable host cells are well known to those skilled in the art.

Expression in eukaryotic cells, such as mammalian, yeast or insect cells, can result in partial or complete glycosylation and/or the relevant interchain or intrachain disulfide bond formation of the recombinant peptide product. Examples of expression vectors in yeast beer include pYepSecl (Baldari et al, (1987), "EMBL J" 6, 229. 234.), pMFa (Kurjan and Herskowitz (1982) cells 30, 933. 943), pJRY88(Schultz et al, (1987) Gene 54, 113. 123) and pYES2(Invitrogen Corporation, San Diego, CA). Baculovirus vectors suitable for protein expression in cultured insect cells (SF9 cells) include the pAc series (Smith et al (1983) molecular cell biology, Vol. 3, 2156-2165) and the pVL series (Lucklow, V.A. and Summer, M.D. (1989) virology, Vol. 170, pp. 31-39). Typically, COS cells (Gluzman. Y. (1981) cells 23, pp.175-182) are used with vectors such as pCDM8(Aruffo, A. and Seed, B. (1987) Proc. Natl.Acad.Sci. USA 84, pp.8573-8577) for transient amplification/expression in mammalian cells, while CHO (dhfr-Chinese hamster ovary) cells are used with vectors such as pMT2PC (Kaufman et al, EMBOJ. 6, pp.187-195) for stable amplification/expression in mammalian cells. Vector DNA can be introduced into mammalian cells by conventional techniques such as calcium phosphate or calcium chloride co-precipitation, DEAE-dextran-mediated transfection or electroporation. Suitable methods for transforming host cells are described in Sambrook et al (molecular cloning: A laboratory Manual, 2 nd edition, Cold spring harbor laboratory Press (1989)) and other laboratory texts.

Expression in prokaryotes is generally carried out in E.coli using either fusion or non-fusion inducible expression vectors. The fusion vector is usually added to the expressed target gene in a certain amount A terminal amino acid. These The terminal amino acid is often referred to as a reporter group. These reporter groups serve two purposes: 1) increase the solubility of the target recombinant protein, 2) as a ligand in affinity purification to facilitate purification of the target recombinant protein. Typically, in fusion expression vectors, a proteolytic cleavage site is introduced at the junction of the reporter group and the target recombinant protein to allow separation of the target recombinant protein from the reporter group after purification of the fusion protein. Such enzymes and their associated recognition sequences include factor Xa, thrombin and enteropeptidase. Exemplary fusion expression vectors include pGEX ((Amrad Corp., Melbourne, Australia), pMAL (New England BioLabs, Beverly, MA), and pRIT5(Pharmacia, Piscataway, N.J.), in which glutathione S-transferase, maltose E binding protein, or protein A, respectively, is fused to a target recombinant protein.

Inducible non-fusion expression vectors include pTrc (Amann et al (1988) Gene 69, pp. 301-315) and pETlld (student et al, Gene expression technology: methods in enzymology 185, Academic Press, San Diego, California (1990) pp. 60-89). Expression of the target gene in pTrc depends on host RNA polymerase transcription from the trp-lac hybrid fusion promoter, and expression of the target gene inserted into pETlld depends on transcriptionfrom the T7gn10-lac0 fusion promoter mediated by co-expressed viral RNA polymerase (T7 ngl). This viral polymerase is provided by the lambda phage present in host strain BL21(DE3) or HMS174(DE3) carrying T7ngl under the transcriptional control of the lacUV5 promoter.

For example, a host cell transfected with a nucleic acid vector directing a nucleotide sequence encoding a helicobacter pylori polypeptide can be cultured under appropriate conditions to allow expression of the polypeptide. The polypeptide can be secreted and isolated from the cell and culture medium mixture containing the peptide. Alternatively, the polypeptide may be retained in the cells, the cells collected, lysed and the protein isolated. Cell cultures include host cells, culture media, and other byproducts. Media suitable for cell culture are well known in the art. The polypeptides of the invention may be isolated from the culture medium, the host cells or a mixture of both using protein purification methods well known in the art, including ion exchange chromatography, gel filtration chromatography, ultrafiltration, electrophoresis and immunoaffinity purification using antibodies specific for these peptides. In addition, in many instances, polypeptides can be prepared from native proteins by chemical cleavage (e.g., trypsinization), and the cleavage product can then be purified using standard techniques.

In the case of membrane bound proteins, the separation is carried out by contacting the membrane bound protein fraction with a detergent to form a soluble complex, wherein the membrane bound protein is no longer completely present in the membrane fraction and is at least to some extent soluble so as to be chromatographically separated from the membrane fraction. There are several different criteria for selecting detergents suitable for solubilizing these complexes. For example, one contemplated property is that the detergent solubilizes helicobacter pylori protein in the membrane fraction but minimally denatures the membrane-bound protein, thereby allowing the protein to regain the ability of membrane-bound protein activity or function upon renaturation. Another property to consider in selecting a detergent is the Critical Micelle Concentration (CMC) of the detergent, in which respect the detergent preferably has a high CMC value so as to be easily removed after renaturation. A third property that is considered in the selection of detergents is their hydrophobicity. Typically, membrane bound proteins are highly hydrophobic, so hydrophobic detergents such as the triton series are useful for solubilizing hydrophobins. Another important property of detergents is the ability of detergents to remove H.pylori protein with minimal protein-protein interactions, thereby facilitating further purification. A fifth considered property of the detergent is the charge of the detergent. For example, if it is desired to use an ion exchange resin in the purification step, the preferred detergent should be an uncharged detergent. Chromatographic techniques that can be used in the final purification step are well known in the art and include hydrophobic interaction, lectin affinity, ion exchange, dye affinity, and immunoaffinity chromatography.

One strategy for maximizing the expression of H.pylori polypeptides in E.coli is to express the protein in host bacteria with an impaired ability to proteolytically cleave recombinant proteins (Gottesman, S.,. Gene expression technology: methods in enzymology 185, academic Press, San Diego, Carlifnia (1990) 119-128). Another strategy is to alter the nucleic acid encoding the H.pylori polypeptide inserted into the expression vector so that the codons encoding each amino acid are those preferentially used in highly expressed E.coli proteins (Wada et al (1992) nucleic acids Res. 20, 2111. multidot. 2118). Such alteration of the nucleic acids of the invention can be carried out using standard DNA synthesis techniques.

The nucleic acids of the invention can also be chemically synthesized using standard techniques, and a variety of methods are known for chemically synthesizing polydeoxyribonucleotides, including solid phase synthesis, which, like peptide synthesis, is entirely automated using commercially available DNA synthesizers (see, e.g., Itakura et al, U.S. Pat. No.4,598,049; Caruthers et al, U.S. Pat. No.4,458,066; and Itakura et al, U.S. Pat. Nos. 4,401,796 and 4,373,071, incorporated herein by reference.

Hp polypeptides

The invention includes isolated helicobacter pylori polypeptides encoded by the disclosed helicobacter pylori genomic sequences, including the polypeptides contained in the sequence listing. The polypeptide of the invention is preferably at least 5 amino acids in length. Using the DNA sequence information provided herein, the amino acid sequences encompassed by the present invention can be deduced using methods well known in the art. It will be appreciated that the sequence of the complete nucleic acid encoding the H.pylori polypeptide is identified separately on the basis of the ORF that is involved in a part of the coding region of the relevant protein. This can be done, for example, by using the isolated nucleic acid encoding the ORF or a fragment thereof as a primer and helicobacter pylori genomic DNA as a template for polymerase chain reaction, followed by sequencing of the amplified product.

The polypeptides of the invention may be isolated from wild-type or mutated H.pylori cells or from heterologous organisms or cells (including but not limited to bacterial, yeast, insect, plant and mammalian cells) into which H.pylori nucleic acid has been introduced and expressed. In addition, the polypeptide may be part of a recombinant fusion protein.

The H.pylori polypeptides of the invention can be chemically synthesized using commercially available automated synthesis methods such as those described herein.

Many of the polypeptides of the invention are related to each other, and some of these relationships are described in tables 3-6 below. All polypeptides in Table 3 are from the stop codon to the stop codon in the length of the H.pylori nucleotide sequence. It is well known in the art that the actual polypeptide length is usually shorter than the length from the stop codon to the stop codon, because the initiation codon for tRNA binding with the initial charge usually occurs several nucleotides downstream of the preceding stop codon and several nucleotides after the ribosome binding site (also called "Shine-Delagarno sequence"). Since most of the binding sites for H.pylori ribosomes have the same characteristics as the general characteristics known in E.coli, the skilled person can expect a very reliable actual start codon from the stop codon to the stop codon nucleotide sequence of one open reading frame. The polypeptide sequence of SEQ ID NOs 492-743 of the invention represents the stop codon-stop codon length of the open reading frame of SEQ ID NOs 1-252. All other polypeptide sequences of the invention represent the length of the protein from the start codon to the stop codon expected from the nucleotide. One skilled in the art should be able to recognize the start site of the open reading frame from the stop codon to the stop codon of the nucleotide sequence given herein. In addition, one skilled in the art will occasionally detect other initiation sites, some of which may be utilized by cellular machinery in vivo. The number of these other initiation sites is very small and one skilled in the art can detect them in recombinant expression systems well known in the art to determine which provides the true functional protein product.

The relationship between the polypeptides shown in Table 3 can be described as follows. First, most of all polypeptides in table 3 are at least 90% identical over most of their length, and most are more than 95% identical. Second, some polypeptides differ in length from stop codon to stop codon in homologous pairs. In some cases, the shorter polypeptide contains a relevant portion of the protein for which the present invention is shown to be useful; in some cases, longer polypeptides may show improved utility. Third, some of the polypeptides in column two are homologous to the two shorter polypeptides in column five.

In all cases, the homology relationships presented in Table 3 are very clear. For example, a typical H.pylori gene product shows 92% to 100% amino acid sequence identity with different strains of H.pylori selected from patients. Nucleotide sequences encoding related polypeptides of the invention are very similar to each other. For example, nucleotide probes derived from the coding sequence of a polypeptide of the invention can be used in PCR or hybridization experiments to identify clones containing nucleotide sequences encoding homologous related polypeptides.

TABLE 3

ORF names	aa Seq ID#	Length of	ORF names	aa Seq ID#	Length of	Difference in length	% homology	Overlap
									01ae11010_40688_c2_38	745	261	hp3e11075orf3	632	261	0	100％	261
01ae12001_24218781_f2_18	746	148	05gp11901orf19	553	370	-222	95％	149
									01ae12001_24218781_f2_18	746	148	07gp11807orf17	568	195	-47	100％	143
01ge10203_35281542_c3_16	797	261	01ge10203orf7	659	154	107	91％	138
									01ge10203_35281542_c3_16	797	261	01ge10203orf14	657	71	190	99％	69
01ge10203_860166_f3_9	798	233	01ge10203orf6	658	233	0	100％	233
									01ge11619_13788141_c2_11	799	105	11ge10309orf4	687	105	0	100％	105
01ge11619_23711062_c3_14	747	319	11ge10309orf12	579	319	0	100％	319
									01ge11619_24415880_c2_12	800	173	11ge10309orf5	688	173	0	100％	173
01ge11619_24417813_c1_8	801	324	11ge10309orf24	684	324	0	100％	324
									01gp11016_4103403_c2_13	748	145	01gp11016orf13	508	123	22	100％	123
02ae11612_1074212_f1_1	749	103	02ae11612orf1	509	103	0	100％	103
									02ae11612_22477267_f2_27	750	304	03xe11215orf7	529	152	152	94％	148
02ae11612_23598175_f1_2	751	332	02ae11612orf15	510	332	0	100％	332
									02ae11612_33203250_c1_51	752	509	05cp11911orf35	549	206	303	99％	205
02ep20506_24611 325_f2_6	835	256	01ce11513orf17	500	256	0	100％	256
									02ge10116_36367936_c1_19	753	173	02ge20116orf25	521	173	0	100％	173
02ge11622_21695936_c1_54	839	313	13ee10216orf57	743	313	0	98％	313
									02ge11622_875260_f3_36	754	523	13ee10216orf7	586	523	0	100％	523
02gp20706_1203402_c3_58	755	162	09ge70821orf2	574	162	0	100％	162
									02gp20706_15781452_c2_51	756	97	06ge10115orf17	563	97	0	100％	97
02gp20706_16803513_f1_1	802	488	01cp11710orf16	652	64	424	98％	63
									02gp20706_16803513_f1_1	802	488	01cp11710orf5	655	247	241	99％	247
02gp20706_16803513_f1_1	802	488	01cp11710orf5	654	146	342	99％	145
									02gp20706_20365905_f2_8	803	198	01cp11710orf9	656	130	68	95％	130
02gp20706_20365905_f2_8	803	198	01cp11710orf18	653	85	113	100％	75
									02gp20706_23632775_f3_32	757	230	06ge10115orf4	565	230	0	100％	230

Table 3 (continuation)

02gp20706_23866562_c2_53	758	120	06ge10115orf19	564	84	36	96％	84
									02gp20706_4892558_f3_19	759	218	01cp11710orf1	502	218	0	100％	218
02gp20814_24415958_f3_9	760	176	14ee10308orf4	594	176	0	99％	176
									02gp20814_3984818_f1_1	804	215	14ee10308orft	593	68	147	97％	67
02gp20814_3984818_f1_1	804	215	14ee10308orf7	694	155	60	100％	143
									04cp11202_16603425_c2_72	805	185	14cp10119orf1	692	161	24	96％	158
04cp11202_19797128_f1_5	806	199	04ge11713orf10	665	132	67	100％	127
									04cp11202_23553177_c1_75	807	372	06ap10209orf4	674	88	284	96％	79
04cp11202_23553177_c1_75	807	372	06ap10209orf1	673	186	186	98％	179
									04cp11202_23553177_c3_109	808	372	06ap10209orf4	674	88	284	96％	79
04cp11202_23553177_c3_109	808	372	06ap10209orf1	673	186	186	98％	179
									04cp11202_24256567_c3_117	744	536	04ge11713orf35	601	200	336	99％	195
04cp11202_24256567_c3_117	744	536	04ge11713orf28	666	122	414	91％	111
									04cp11202_24256567_c3_117	744	536	04ge11713orf36	667	250	286	97％	234
04cp11202_24261588_f2_23	761	96	01ae12021orf5	492	96	0	100％	96
									04ge10816_22086531_f2_10	809	208	04ge11210orf1	664	208	0	100％	208
04ge10816_33726080_c2_29	810	369	13ae10610orf1	690	133	236	98％	120
									05ae30220_21619067_f3_56	763	293	05ae20220orf58	544	293	0	100％	293
05ae30220_24882812_c3_103	765	486	05ae20220orf119	542	486	0	100％	486
									05ae30220_25953163_c3_98	766	81	05ae20220orf95	545	81	0	100％	81
05ae30220_9882767_f2_34	812	69	05ae20220orf37	671	69	0	100％	69
									05cp21223_4725443_f3_14	813	113	hp1e10506orf5	696	113	0	100％	113
05ee10816_14649077_f3_18	767	263	04ce11617orf4	534	152	111	97％	144
									05ee10816_259703_f2_7	814	158	04ce11617orf10	661	142	16	93％	142
05ee10816_4103408_f2_11	768	115	04ce11617orf16	531	115	0	100％	115
									05ee10816_4687651_c1_22	769	953	04ce11617orf27	519	676	277	100％	676
05ee10816_4687651_c1_22	769	953	04ce11617orf26	532	238	715	100％	238
									06ap11119_16594193_f1_9	770	87	11ge10309orf7	580	87	0	100％	87
06ap11119_24426508_f3_26	815	120	11ge10309orf28	685	137	-17	100％	121
									06ap11119_24426508_f3_26	815	120	hp4e12063orf1	699	86	34	100％	65
06ap20306_23437632_f3_9	771	291	04gp11803orf13	541	243	48	99％	228

Table 3 (continuation)

06cp30603_23452_c3_80	772	176	06cp30603orf16	560	159	17	97％	155
									06cp30603_23476568_c1_44	773	442	05cp20518orf39	550	442	0	100％	442
06cp30603_4689068_c3_79	774	100	06cp30603orf15	559	100	0	100％	100
									06ee10709_21675012_f1_2	816	284	06ee10709orf2	675	284	0	100％	284
07ap11015_23938312_f3_2	762	271	07ap11015orf2	622	95	176	100％	94
									07ap11015_23938312_f3_2	762	271	07ap11015orf4	624	211	60	99％	177
07ap11111_234693_c3_14	775	209	07ap11111orf13	566	209	0	100％	209
									07ap11213_35156577_c1_24	836	401	hp2e10911orf35	718	420	-19	99％	399
07ap11213_35401528_c1_21	764	803	hp2e10911orf25	672	458	345	100％	458
									07ap11213_35401528-c1_21	764	803	hp2e10911orf24	620	344	459	100％	344
07ap20216_7227202_f3_10	776	532	05ap21216orf4	547	529	3	100％	529
									07ap80601_976413_f3_9	837	274	07ap80601orf2	633	268	6	100％	265
07ce11019_22051291_f1_1	817	600	07cp21714orf1	678	193	407	99％	190
									07ce11019_22051291_f1_1	817	600	07cp21714orf3	679	418	182	100％	414
07ep11916_5273452_c3_31	777	255	01cp11414orf2	501	255	0	100％	255
									07ep11916_5913592_f3_18	818	272	01cp11710orf5	654	146	126	93％	111
09cp11003_19532625_c3_17	778	357	14ge10705orf14	599	357	0	99％	357
									09cp11003_5945252_f2_4	819	219	14ge10705orf3	695	219	0	100％	219
09cp20502_24001388_c1_31	779	61	14gp11820orf1	600	61	0	100％	61
									09ze10333_22460750_f2_6	820	729	03ge10505orf2	660	323	406	97％	312
12ge10321_24308513_f3_20	840	242	06gp11920orf11	741	242	0	99％	242
									12ge10321_4821082_f3_14	821	172	hp4p11352orf9	683	115	57	100％	115
12ge10321_4821082_f3_14	821	172	hp4p11352orf5	701	68	104	92％	64
									12gp31106_3024126_f2_25	780	147	13ap11517orf15	585	147	0	100％	147
13ae10712_14100018_f2_12	781	201	14cp10705orf4	592	201	0	99％	201
									13ae10712_29569208_c2_27	782	264	13ae10712orf15	584	264	0	100％	264
14ap10221_13689381_c3_4	822	366	05gp11901orf19	553	370	-4	96％	360
									14ap10221_13689381_c3_4	822	366	06ep10306orf1	676	66	300	100％	66
14ap108f5_20585777_c1_13	783	677	hp3e10349orf27	628	677	0	100％	677
									14ce21516_85786_f1_1	841	700	14ce21516orf1	533	361	339	98％	350
14ce21516_85786_f1_1	841	700	04ap20904orf3	740	284	416	95％	271

Table 3 (continuation)

29ep10720_24220926_f2_8	823	86	hp4e12063orf1	699	86	0	100％	86
									29ep10720_24220926_f2_8	823	86	11ge10309orf28	685	137	-51	100％	81
29ep10720_24432762_c3_39	824	227	11ge10309orf39	686	227	0	100％	227
									29ge30321_12913562_f1_1	825	79	01ce11618orf22	648	79	0	100％	79
29ge30321_135253_f2_6	826	101	01ce11618orf7	650	101	0	97％	101
									29ge30321_21673965_f2_7	827	488	01ce11618orf9	651	409	79	100％	409
29ge30321_24336712_f1_5	828	422	01ce11618orf11	647	188	234	93％	181
									29ge30321_24336712_f1_5	828	422	01ce11618orf27	649	235	187	96％	235
29ge30321_34157812_f3_10	784	342	01ce11618orf24	498	86	256	97％	85
									hp1p14013_11726503_c2_20	785	149	hp1p14013orf17	617	149	0	99％	149
hp2p10272_22692325_f3_21	829	188	09ap20802orf13	680	163	25	99％	149
									hp2p10272_23697200_f3_22	786	329	09ap20802orf14	570	278	51	100％	276
hp2p10272_24406280_c1_26	830	194	09ap20802orf21	681	194	0	100％	194
									hp2p10272_26829136_f1_1	787	343	hp2p10272orf1	625	343	0	100％	343
hp3p10807_189075_f2_4	838	312	hp3p10807orf6	728	325	-13	99％	312
									hp3p10807_29343768_f1_1	831	187	hp3p10807orf4	697	187	0	100％	187
hp3p10807_29352212_f2_5	832	230	hp3p10807orf7	698	230	0	100％	230
									hp5e15211_819455_c2_24	788	269	hp5e15211orf23	641	269	0	100％	269
hp5p15212_34064750_f2_9	789	148	02ce10213orf19	515	148	0	98％	148
									hp5p15641_21698387_c2_20	790	185	hp5p15641orf23	644	185	0	98％	185
hp6e10967_23476502_f2_6	791	165	hp2p10625orf5	626	165	0	99％	165
									hp6e10967_24882750_f2_7	792	157	hp2p10625orf6	627	157	0	100％	157
hp6e12267_14650278_f3_29	842	277	12ge20305orf26	742	277	0	98％	277
									hp6e12267_4876718_f2_23	793	143	12ge10305orf5	582	146	-3	98％	146
hp6e20339_1190660_c2_46	794	69	04gp11213orf22	540	69	0	100％	69
									hp6e20339_21492187_c1_40	795	106	04gp11213orf14	539	136	-30	99％	106
hp6e20339_24317062_c3_57	833	382	04gp11213orf5	669	382	0	99％	382
									hp6e20339_34024187_c1_37	796	122	04gp11213orf11	538	122	0	100％	122
hp6p10233_12273302_11_1	834	143	07cp10312or15	677	138	5	95％	105

Other relationships between the polypeptides of the present invention are described in Table 4 below, and the length of all polypeptides in Table 4 is measured from stop codon to stop codon in the nucleotide sequence of H.pylori.

The relationships between the polypeptides shown in Table 4 can be introduced as follows. First, all polypeptides in table 4 are at least 90% identical over most of their length, and most are more than 95% identical. Second, some polypeptides differ in length from stop codon to stop codon in homologous pairs. In some cases, the shorter polypeptide contains a relevant portion of the protein for which the present invention is shown to be useful; in some cases, longer polypeptides may show improved utility. Third, some of the polypeptides in column twoare homologous to the two shorter polypeptides in column five.

In all cases, the homology relationships presented in Table 4 are very clear. For example, a typical H.pylori gene product shows 92% to 100% amino acid sequence identity with different strains of H.pylori selected from patients. Nucleotide sequences encoding related polypeptides of the invention are very similar to each other. For example, nucleotide probes derived from the coding sequence of a polypeptide of the invention may be used in PCR or hybridization experiments to identify probes containing sequences encoding homologous sequencesCloning of nucleotide sequences of related polypeptides. TABLE 4

ORF names	aa Seq ID#	Length of (aa)	ORF names	aa Sea ID#	Length of (aa)	％ Are identical to each other	Overlap (aa)	Length of Variations in
									01ce11104_36125337_c1_8	849	74	hp1e10523orf3	612	63	100	63	11
01ce21104_33203250_c3_87	850	509	05cp11911orf35	549	206	100	204	303
									01cp20708_36134808_f2_11	928	230	4ee10419orf5	704	229	100	229	1
02ae31010_12504512_f3_28.aa	929	490	01ge10801orf2	514	60	95	56	430
									02ae31010_16833312_f2_19	930	181	02ce11022orf2	530	184	98	181	-3
02ae31010_2117087_f3_34	931	137	07ce10203orf17	635	76	97	77	61
									02ae31010_30208317_f1_14	932	343	hp1p13947orf10	717	343	100	343	0
02ae31010_34616666_f2_27	851	184	01ce11618orf1	503	124	99	125	60
									02ae31010_34616666_f2_27	851	184	hp1p13947orf11	616	81	94	77	103
02ae31010_35270000_f3_33	852	231	01ep11504orf5	505	156	99	156	75
									32ae31010_36132785_f2_29	853	438	01ce11618orf3	499	67	98	64	371
02ae31010_36132785_f2_29	853	438	01ce11618orf13	504	378	97	387	60
									02ae31010_5085162_c1_47	934	416	07ce10203orf11	634	416	100	416	0
02cp10615_26573462_c1_45	935	168	hp3p10304orf2	727	126	91	129	42
									02ge10116_15781452_c1_87	854	97	06ge10115orf17	563	97	100	97	0
02ge10116_16803513_f2_34	855	488	01cp11710orf16	652	64	100	62	424
									02ge10116_16803513_f2_34	855	488	01cp11710orf5	654	146	99	145	342
02ge10116_36367936_c1_92	857	173	02ge20116orf25	521	173	100	173	0
									03ae10804_12609533_c1_26	936	257	06ep10306orf10	610	257	100	257	0

hp6p10903_4398263_f3_6.aa	924	370	05gp11901orf19	553	370	100	370	0
									hp6p10903_4398263_f3_6.aa	924	370	05gp11901orf19	553	370	100	370	0
03ae10804_21698400_c2_32	937	386	06ep10306orf11	611	386	100	386	0
									03ae10804_23485968_c3_47	858	88	06ep10306orf5	561	88	100	88	0
04ep41903_26757937_f3_16	938	703	29ap10306orf3	711	325	97	319	378
									04ep41903_26757937_f3_16	938	703	29ap11902orf1	712	280	92	280	423
04ep41903_4101593_f2_10.aa	940	1240	14ee21118orf1	706	365	96	358	875
									05ce10910_25598277_f3_3	859	258	07ee11519orf1	567	170	96	166	88
05ep10815_26570332_c2_99	941	183	12ge10610orf2	702	97	98	97	86
									05ep10815_4195292_c1_84	942	441	hp1e10554orf7	715	103	99	94	338
05ep10815_4719175_c1_83	943	663	06ee10207orf1	606	99	99	99	564
									06ae11016_30579712_f2_21	860	239	03ce21717orf1	526	193	99	193	46
06ce20610_1367157_f1_8.aa	844	248	29ge10111orf3	714	124	90	121	124
									06ce20610_29298537_c2_32	861	234	05gp20111orf4	555	234	100	234	0
06ce20610_3913967_c3_36	862	283	05gp20111orf6	556	283	100	283	0
									06ce20610_4331338_f3_18	863	353	05gp20111orf12	554	243	99	245	110
06cp11118_212827_c1_17	864	73	06cp11118orf7	558	73	100	73	0
									06cp11217_19720300_f3_11	865	308	hp1p13852orf6	614	646	96	278	-338
06cp11217_4881263_f2_9	866	93	hp1p3852orf7	615	93	100	93	0
									06cp11217_4897077_f1_6	867	100	hp1p13852orf4	613	100	100	100	0
06cp30603_21492187_f2_41	868	106	04gp11213orf14	539	136	98	106	-30
									06cp30603_34024187_f1_20	869	483	04gp11213orf11	538	122	100	122	361
06cp30603_34024187_f1_20	869	483	04gp11213orf5	669	382	95	377	101
									06cp30603_679218_f2_34	944	380	hp3e10302orf17	721	231	98	236	149
06ep10615_14649077_f3_52	871	300	04ce11617orf4	534	152	96	145	148
									06ep10615_961562_f2_41	945	636	29ep20112orf2	713	135	98	87	501
06ep10615_9842_f3_46	872	159	05ep11717orf2	552	192	99	159	-33
									06ep11202_133293_c1_19	946	167	06cp20302orf3	602	167	100	167	0
06ep11202_26353438_c1_22	873	286	hp2e11858orf6	623	155	100	154	131
									06ep11202_26353438_c1_22	873	286	02ae21214orf1	522	109	92	110	177
06ep11202_792962_c2_26.aa	949	151	06cp20302orf6	604	66	92	66	85
									06ep11202_4884677_c1_17	948	171	06cp20302orf5	603	171	99	171	0
06ep11917_24803153_c3_24	848	409	hp4e14535orf3	536	253	98	239	156
									06ep11917_24803153_c3_24	848	409	hp4e14535orf7	730	60	97	60	349
06ep30223_16512_c3_160	951	231	hp3e10128orf1	720	231	100	231	0
									06ep30223_23476067_c1_119	952	151	01ep30520orf8	511	94	93	95	57
06ep30223_23557202_c2_130	874	329	hp3e11024orf49	630	329	100	329	0
									06ep30223_34409437_f3_94	875	148	hp3e11024orf5	631	148	100	148	0
06ep30223_4698838_f2_55	845	663	4gp12015orf13	662	344	100	334	319
									06ep30223_4698838_f2_55	845	663	4gp12015orf16	663	117	99	112	546
06ep30223_4876077_c3_149	877	113	hp3e11024orf34	629	113	100	113	0
									06ep30223_5109443_c1_109	878	342	05ee10411orf5	551	293	95	287	49
06ep30223_5271902_c1_106	879	207	hp2e10229orf4	619	80	95	38	127
									06gp10409_3398427_f2_12	880	115	3ae10511orf3	583	115	92	115	0
06gp71906_15115637_f2_59	953	158	hp4p11393orf2	733	158	100	158	0
									06gp71906_24261588_c2_174	881	96	01ae12021orf5	492	96	100	96	0
06gp71906_25478192_c1_131	954	236	hp3e11122orf3	723	236	100	236	0
									06gp71906_25504187_f3_112	955	443	hp4p11393orf1	732	169	91	155	274
06gp71906_970325_c3_190	882	158	02ap21113orf2	512	113	92	98	45
									07ae10923_24426508_f1_1	883	137	1ge10309or128	685	137	100	137	0
07ae10923_24426508_f1_1	883	137	1ge10309orf28	685	137	100	137	0
									09ce10413_414011_f1_3	885	169	02ce10216orf6	516	172	100	169	-3

09ce10413_5865665_f1_4	886	353	02ce10216orf7	517	74	100	74	279
									09ce52017_29324062_c1_21	887	141	01ep30520orf24	506	141	100	141	0
09cp10224_1062966_c3_61	888	367	05ce10420orf1	548	194	100	194	173
									09cp10224_1412715_c3_56	889	185	01ce10516orf20	495	185	100	185	0
09cp10224_429510_c2_46.aa	890	316	01ce105160rr21	496	108	98	108	208
									09cp10224_4484718_c1_38	891	581	01ce10St60rf15	493	301	99	297	280
09cp21607_72241_87__c2_12	892	72	07gp31516orf9	569	72	100	72	0
									09cp61003_14562637_c2_93	893	106	03gp20123orf3	527	80	98	83	26
09cp61003_19532625_c1_78	894	357	14ge10705orf14	599	357	99	357	0
									09cp61003_24063587_c1_74	895	201	11ee10423orf1	577	116	100	116	85
09cp61003_24335762_c3_111	896	204	11ee10423orr4	578	105	100	104	99
									09cp61003_492187_c2_80.aa	956	667	06gp10103orf2	621	266	98	266	401
09cp61003_5945252_f1_5	897	219	14ge10705orb	695	219	100	219	0
									11ae80818_11188791_c3_60	898	221	11ap11902orf3	575	185	99	185	36
11ae80818_19632781_c3_57	957	100	06cp11722orf11	595	100	100	100	0
									11ae80818_7290627_c2_51	958	152	06cp11722off5	598	98	100	93	54
11ae80818_783127_c3_63	899	182	03ap21320off4	523	182	100	182	0
									11ae80818_7952_c1_49	900	148	03ap21820orf8	524	148	100	148	0
11ap20714_34023312_f3_46	959	285	hp3e10057orf3	719	285	100	285	0
									11ap20714_4960432_c3_97	901	151	14ee11217orf2	596	100	100	88	51
11aP20714_5271 967_c1_60	902	260	14ee11217orf3	597	231	100	227	29
									11ap20714_7227202_f3_43.aa	903	798	05ap21216orf4	547	529	100	529	269
11ap20714_7227202_f3_43.aa	903	798	05ap21216orf4	547	529	100	529	269
									11ee11408_4977193_c1_41.aa	960	497	14ep11115orf3	708	91	100	91	406
11ge10308_5256_f2_1	961	71	11ge10308orf1	693	71	100	71	0
									12ap10324_13178562_f3_6	962	269	12ap10324orf8	700	164	99	164	105
12ap10324_4805318_f2_3	846	326	12ap10324orf6	581	95	100	77	231
									12ap10324_4805318_f2_3	846	326	12ap10324orf5	645	215	99	213	111
14ce31519_15635927_f3_15	905	293	02ce10809orf6	518	293	100	293	0
									14ce61516_13073577_f2_12	963	784	14ep11905orf13	709	721	100	526	63
14ce41924_16282067_c1_72	964	64	02ep30607orf32	546	104	97	63	-40
									14ee41924_23527267_c3_107	906	233	02cp30607orf27	520	138	98	97	95
14ee41924_23834800_f2_32	907	298	11ce10917orf10	639	298	100	298	0
									14ee41924_2458267_c2_93	847	1304	02cp30607off19	590	407	99	397	897
hp1p13939_25397327_13_22	908	228	06ce10808orf2	557	151	100	145	77
									hp2e10911_24855312_c1_69	909	161	11cp12006orf13	576	105	95	112	56
hP2e10911_3349_c1_63	910	113	01ce11618orf22	648	79	100	65	34
									hp2e10911_4882027_c2_87	965	583	01cp11108orf6	507	101	99	99	482
hp3e11188_47327_f2_5	966	368	hp1p3p10307orf6	728	325	96	323	43
									hp3e11188_5082842_f3_12	967	89	06ee11611orf1	608	89	100	89	0
hp4e13394_3368767_c1_80	968	804	09ap11406orf2	668	804	100	804	0
									hP4e13394_35957200_f1_21	911	233	06ep11108orf17	S62	165	100	147	68
hp4e13394_5964452_c2_97	912	79	02ap71220orf2	513	79	100	79	0
									hp4e53394_22864682_c2_86.aa	913	427	hp1p13852orf6	614	646	100	422	-219
hp5e15044_4554652_f3_3	914	146	07cp10312orf5	677	138	100	138	8
									hp5p15212_6928132_c3_34	969	270	11ce10908orf1	682	165	93	169	105
hp5p15575_29300311_c1_29	915	152	14ce10720orf3	591	163	95	152	-11
									hp5p15575_33445317_f2_20.aa	916	294	hp3p11086orf1	636	217	92	202	77
hp5p15575_6140713_12_18	917	288	14ce10720orf12	589	288	100	288	0
									hp5p15641_12195281_c1_24	918	92	hp5p15612orf2	643	92	100	92	0
hp5p15641_24304S27_c3_35	919	139	29ge10307orf4	609	103	98	102	36
									hp5p15641_25635452_c3_34	920	92	29gc10307orf3	607	92	100	92	0

hp5p15641_30273312_c2_28	970	301	05ce10613orf1	572	79	91	70	222
									hp5p15641_30273312_c2_28	970	301	05ce10613orf2	573	61	100	54	240
hp5p15641_5211687_c2_29	971	297	05ap10914orf3	571	60	98	60	237
									hp5p15870_14350428_f1_1	921	84	05ae20220orf56	543	101	99	79	-17
hp6p10590_23440913_c2_31	922	371	04ee70114orf10	535	243	98	235	128
									hp6p10590_30521093_f2_14	972	138	07ce11206orf1	637	107	97	107	31
hp6p10606_19546933_c3_31	923	283	13ep12003orf21	587	222	92	228	61
									hp6p10904_2214676_c1_14	926	179	hp4p13446orf3	640	179	99	179	0
hp6p10904_23704412_f2_5	927	384	hp4p13446of13	638	384	99	384	0
									hp6p10904_7089062_c1_16	973	364	hp4p13446of5	736	364	100	364	0
hp6p12129_16603417_f3_14	974	358	hp3e10302orf26	722	268	98	266	90
									hp6p12244_3948467_c1_52	975	476	hp4p12005orf2	735	108	96	84	368
hp6p22217_23470967_f1_4	976	272	13ee12016orrf7	703	272	100	272	0
									hp7e10192_4412568_f2_5	977	291	02ce10114orf3	525	291	100	291	0
hp7p10287_24611325_c2_24	978	256	01ce11513orf17	500	256	100	256	0
									hp7p10290_25548812_f3_14	979	489	hp3p10156orf2	724	333	100	333	156
hp7p10290_25585941_f3_12	980	374	hp3p10156orf3	725	91	91	87	283
									hp7p10290_35156558_f3_15	981	411	11cp12002orf3	689	109	96	107	302
hp7p10290_4351718_f1_6	982	324	hp3p10156orf7	726	302	95	299	22

Other relationships between the polypeptides of the present invention are described in Table 5 below, and the length of all polypeptides in Table 5 is measured from the stop codon to the stop codon in the nucleotide sequence of H.pylori.

The relationship between the polypeptides shown in Table 5 can be described as follows. First, all polypeptides in table 5 are 90% identical over most of their length; most are 95% identical. Second, cognate pairs of polypeptides vary in length from stop codon to stop codon. In some cases, the shorter polypeptide contains a relevant portion of the protein for which the present invention is shown to be useful; in some cases, longer polypeptides may show improved utility. Third, the polypeptides in column two are homologous to the two shorter polypeptides in column five.

In all cases, the homology relationships presented in Table 5 are very clear. For example, a typical H.pylori gene product shows 92% to 100% amino acid sequence identity with different strains of H.pylori selected from patients. Nucleotide sequences encoding related polypeptides of the invention are very similar to each other. For example, nucleotide probes derived from the coding sequence of a polypeptide of the invention can be used in PCR or hybridization experiments to identify clones containing nucleotide sequences encoding homologous related polypeptides.

TABLE 5

ORF names	aa Seq ID#	Length of (aa)	OR name	aa Seq ID#	Length of (aa)	Difference in length	％ Are identical to each other	Overlap (aa)
									01ce21104_33203250_c3_87	850	502	02ae11612_33203250_c1_51	752	502	0	99.8	502
02ge10116_1 5781452_c1_87	854	97	02gp20706_15781452_c2_51	756	80	17	100	80
									02ge10116_1680351_3_f2_34	855	479	02gp20706_16803513_f1_1	802	486	-7	100	479
02ge10116_16803513_f2_34	855	479	07ep11916_5913592_f3_18	818	269	210	97.66	128
									02ge10116_36367936_c1_92	857	171	02ge10116_36367936_c1_19	753	169	2	100	169
06cp30603_21492187_f2_41	868	89	hp6e20339_21492187_c1_40	795	89	0	97.75	89
									06cp30603_23476568_c2_133.aa	843	437	06cp30603_23476568_c1_44	773	436	1	100	436
06cp30603_340241_f1_20	869	479	hp6e20339_24317062_c3_57	833	357	122	100	357
									06cp30603_34024187_f1_20	869	479	hp6e20339_34024187_c1_37	796	118	361	100	118
06ep10615_14649077_f3_52	871	300	05ee10816_14649077_f3_18	767	263	37	96.74	245
									06gp71906_24261588_c2_174	881	89	04cp11202_24261588_f2_23	761	88	1	100	88
07ae10923_2442658_f1_1	883	133	06ap11119_24426508_f3_26	815	117	16	100	117
									07ae10923_24426508_f1_1	883	133	29cp10720_24220926_f2_8	823	80	53	100	80
09cp61003_19532625_c1_78	894	352	09cp11003_19532625_c3_17	778	333	19	100	333
									09cp61003_5945252_f1_5	897	211	09cp11003_5945252_f2_4	819	198	13	100	198
11ap20714_7227202_f3_43.aa	903	792	07ap20216_7227202_f3_10	776	533	259	100	527
									14ee41_924_2458267_c2_93	847	1288	07ap11015_23938312_f3_2	762	257	1031	100	257
hp2e10911_3349_c1_63	910	110	29ge30321_12913562_f1_1	825	70	40	100	65
									hp3e11188_47327_f2_5	966	368	hp3p10807_189075_f2_4	838	312	56	100	312
hp5e15044_4554652_f3_3	914	114	hp6p10233_12273302_f1_1	834	143	-29	95.58	113
									hp5p15870_14350428_f1_1	921	80	05ae30220_14350428_f1_9	811	748	-668	98.75	80
hp6p10903_4398263_f3_6.aa	924	366	01ae12001_24218781_f2_18	746	119	247	96.64	119
									hp6p10903_4398263_f3_6.aa	924	366	14ap10221_13689381_c3_4	822	338	28	96.45	338
hp7p10287_24611325_c2_24	978	256	02ep20506_24611325_f2_6	835	242	14	100	242

Other relationships between the polypeptides of the present invention are described in Table 6 below, and the length of all polypeptides in Table 6 below is measured from the stop codon to the stop codon in the nucleotide sequence of H.pylori.

The relationship between the polypeptides shown in Table 6 can be described as follows. First, all polypeptides in table 6 are at least 90% identical over most of their length; most are 95% identical. Second, some polypeptides differ in length from stop codon to stop codon in cognate pairs, and in some cases, shorter polypeptides contain the relevant portion of the protein for which the present invention is intended; in some cases, longer polypeptides may show improved utility.

In all cases, the homology relationships presented in Table 6are very clear. For example, a typical H.pylori gene product shows 92% to 100% amino acid sequence identity with different strains of H.pylori selected from patients. Nucleotide sequences encoding related polypeptides of the invention are very similar to each other. For example, nucleotide probes derived from the coding sequence of a polypeptide of the invention can be used in PCR or hybridization experiments to identify clones containing nucleotide sequences encoding homologous related polypeptides.

TABLE 6

ORF names	aa Seq ID#	Length of	ORF names	aa Seq ID#	Length of	Difference in length	Overlap	％ID
									01ae12001_24218781_f2_18	746	149	11ae11922_12586675_f2_1	1037	249	100	149	100.00
02gp20706_23866562_c2_53	758	120	02ge10116_23866562_c3_146	1038	641	521	102	100.00
									07ap11015_23938312_f3_2	762	271	07ee11402_2458267_c3_108	1039	1304	1033	271	100.00
07ap11213_35401528_c1_21	764	803	07ee50709_10213593_f3_77	1040	1484	681	726	100.00
									05ee10816_14649077_f3_18	767	263	06ep10615_14649077_f2_30	1041	300	37	245	96.74
06cp30603_23452_c3_80	772	177	09cp10713_23452_c_195	1042	526	349	177	94.35
									07ap20216_7227202_f3_10	776	533	11ap20714_7227202_f3_40	1043	798	265	533	100.00
09cp11003_19532625_c3_17	778	357	01ce61016_23609580_c3_139	1044	343	-14	342	100.00
									12gp31106_3024126_f2_25	780	147	06gp71906_1024126_c1_128	1045	405	258	143	100.00
13ae10712_14100018_f2_12	781	201	06ge20501_14100018_c1_34	1046	553	352	201	100.00
									hp6e20339_34024187_c1_37	796	122	09cp10713_34024187_f1_31	1047	483	361	122	100.00
01ge10203_35281542_c3_16	797	261	hp4p62853_5914693_c3_52	1048	272	11	261	99.62
									04ge10816_22086531_f2_10	809	208	13ae10610_859692_c2_32	1049	401	193	208	98.56
04ge10816_33726080_c2_29	810	369	13ae10610_35912_f2_3	1050	459	90	361	100.00
									06ap11119_4426508_f3_26	815	121	06ap11119_24426508_f3_27	1051	137	16	121	100.00
07ce11019_22061291_f1_1	817	600	14gp11423_26803801_f3_7	1052	712	112	568	99.82
									14ap10221_13689381_c3_4	822	366	06ap10609_12586675_f2_19	1053	375	9	363	96.69
29ge30321_135253_f2_6	826	101	07cc50709_4818967_12_43	1054	487	386	86	98.84
									hp2p10272_22692325_f3_21	829	188	02ap11117_23495187_c3_81	1055	253	65	188	99.47
hp6e20339_24317062_c3_57	833	382	09cp10713_34024187_f1_31	1056	483	101	377	96.55
									07ap11213_35156577_c1_24	836	401	07ee50709_35156577_f3_80	1057	567	166	400	100.00
07ap80601_976413_f3_9	837	274	05ae30220_976413_c3_204	1058	384	110	274	100.00
									hp3p10807_189075_f2_4	838	312	hp3e1118_47327_f2_9	1059	368	56	312	100.00
12ap10324_4805318_f2_3	846	327	12ap10324_4805318_f2_6	1060	420	93	327	100.00
									03ae10804_23485968_c3_47	858	88	hp1e80523_23485968_c2_49	1061	223	135	85	100.00
05ce10910_25598277_f3_3	859	258	hp7e10192_25598277_c2_15	1062	422	164	254	100.00
									06cp11217_19720300_f3_11	865	308	hpre53394 26209843_c3_98	1063	686	378	278	96.76
06ep10615_9842_f3_46	872	159	06ep10615_9842_f1_5	1064	345	186	159	99.37
									06ep30223_34409437_f3_94	875	148	06ep30223_34409437_f2_64	1065	295	147	147	97.28

Table 6 (continue)

06gp10409_3398427_f2_12	880	116	06gp10409_3398427_f2_12	1066	292	176	116	100.00
									09ce10413_5865665_f1_4	886	74	09ce10413_5865665_f1_4	1067	353	279	74	100.00
09cp10224_1062966_c3_61	888	367	09cp10224_1062966_c1_44	1068	485	118	372	94.09
									09cp61003_14562637_c2_93	893	106	01ce61016_12931513_c2_106	1069	376	270	94	93.62
09cp61003_19532625_c1_78	894	357	01ce61016_23609580_c3_139	1070	343	-14	342	100.00
									11ae80818_11188791_c3_60	898	221	14cp11908_25593768_c3_97	1071	538	317	204	99.51
11ae80818_783127_c3_63	899	182	14cp11908_783127_c1_72	1072	337	155	167	98.20
									14ee41924_23527267_c3_107	906	233	07ee11402_10759567_c2_86	1073	292	59	232	100.00
hp2e10911_3349_c1_63	910	113	07ee50709_4818967_f2_43	1074	487	374	109	95.41
									hp4e13394_35957200_f1_21	911	233	hp4e13394_5088562_f3_54	1075	225	-8	215	100.00
hp4e13394_5964452_c2_97	91 2	79	hp4e13394_15828963_c2_90	1076	135	56	77	100.00
									hp4e53394_22864682_c2_86.aa	913	427	hp4e53394_19720300_c3_98	1077	647	220	422	100.00
hp5e15044_4554652_f3_3	914	146	07ce10312_4554652_f3_2	1078	174	28	146	100.00
									hp5p15870_14350428_f1_1	921	84	05ae30220_14350428_f3_91	1079	752	668	84	98.81
hp6p10606_19546933_c3_31	923	283	hp8e10080_19546933_c2_88	1080	428	145	280	99.29
									01cp20708_36134808_f2_11	928	230	01ce10320_30273587_f3_38	1081	275	45	230	100.00
02ae31010_2117087_f3_34	931	137	07ee50709_26438968_f2_36	1082	265	128	128	98.44
									05ep10815_4719175_c1_83	943	663	05ep10815_4719175_c1_115	1083	925	262	653	100.00
06ep30223_23476067_c1_119	952	1 51	06ep30223_23476067_c1_115	1084	210	59	150	98.67
									11ae80818_7290627_c2_51	958	152	hp7e10590_26172564_c1_68	1085	356	204	141	88.65
11ce11408_4977193_c1_41.aa	960	530	05ae30220_4977193_c3_198	1086	531	1	528	99.05
									11ge10308_5256_f2_1	961	71	hp7e10557_21698387_f1_1	1087	239	168	69	98.55
14ee41924_16282067_c1_72	964	64	07ee11402_19565702_c2_88	1088	465	401	63	100.00
									hp2e10911_4882027_c2_87	965	583	07ee50709_960952_f2_47	1089	1213	630	585	97.78
hp6p12244_3948467_c1_52	975	476	hp6p12244_3948467_c3_88	1090	508	32	445	100.00
									14ce61516_13073577_f2_12	963	785	hp7e10590_13073577_c3_107	1 296	897	112	785	100.00
09cp61003_492187_c2_80	956	667	01ce61016_492187_c3_120	1297	668	1	667	100.00
									06ep10615_961562_f2_41	945	636	06ep10615_961562_f1_15	1298	637	1	636	100.00

IV identification of nucleic acids encoding vaccine components and target sites for agents effective against helicobacter pylori

The helicobacter pylori genomic sequences disclosed include segments directing the synthesis of ribonucleic acids and polypeptides, as well as regions of replication initiation, promoters, other types of regulatory sequences, and intergenic nucleic acids. The invention includes the identification of nucleic acids encoding the immunogenic components of the vaccine and the target site of agents effective against helicobacter pylori. An important aspect of such identification is the determination of the function of the disclosed sequences, which can be accomplished in a variety of ways. Non-limiting examples of these methods are briefly described below.

Known sequence homology: computer-assisted comparison of the disclosed H.pylori sequences with previously reported sequences present in public databases is a useful tool for identifying functional H.pylori nucleic acid and polypeptide sequences. It is understood that the sequences encoding the proteins, for example, should be compared as a whole, and that the high homology of the sequences at the amino acid level (e.g.,>80-90%) of the two proteins strongly suggests that the two proteins also have some degree of functional homology, for example, between enzymes involved in metabolism, DNA synthesis or cell wall synthesis, and between proteins involved in trafficking, cell division, etc. In addition, many structural features of a particular protein family have been identified and associated with particular consensus sequences, such as, for example, binding regions for nucleotides, DNA, metal ions, and other small molecules; sites for covalent modification such as phosphorylation, acetylation, etc.; protein: sites of protein interaction, etc. These consensus sequences may be so short that they may represent only a part of the coding sequence of the complete protein. Thus, the determination of such characteristics in the H.pylori sequence is very useful for determining the function of the encoded protein and for determining the target site for potential use of the antibacterial agent.

Of particular relevance to the present invention are structural features that are very common to secretory, transmembrane and surface proteins, including secretory signal peptides and hydrophobic transmembrane regions. The identification of helicobacter pylori proteins containing putative signal sequences and/or transmembrane regions is very useful as an immunogenic component of a vaccine.

Identification of essential genes: nucleic acids encoding proteins essential for the growth or survival of H.pylori are preferred drug targets. The biological relationship of the H.pylori gene to the organism can be examined by examining the deletion and/or disruption of the gene, i.e.by so-called "gene" knock-out ", using techniques well known to those skilled in the relevant art. In this way, essential genes can be identified.

Strain-specific sequences: because of the evolutionary relationship between different H.pylori strains, it is believed that the H.pylori sequences disclosed herein are useful for the identification of, and/or discrimination between, previously known and newH.pylori strains. It is believed that other strains of H.pylori will exhibit at least 70% sequence homology with the sequences disclosed herein, although it is not important to the present invention whether this is the case. Systematic and routine analysis of DNA sequences from samples containing H.pylori strains, and comparison with the sequences of the invention, allows identification of sequences that can be used to distinguish between the different strains, as well as sequences that are common to all H.pylori strains. In one embodiment, the invention provides nucleic acids, including probes, and peptide and polypeptide sequences, that distinguish between different strains of helicobacter pylori. Strain-specific components may also be identified by their ability to produce or react with antibodies that specifically recognize one or more H.pylori strains.

In another embodiment, the invention provides nucleic acids, including probes, as well as peptide and polypeptide sequences, that are common to all H.pylori bacteria but are not found in other bacterial species.

The specific embodiment is as follows: identification of candidate protein antigens for development of antibodies and vaccines

Candidate protein antigens for the selection of vaccines for development may be derived from nucleic acids encoding helicobacter pylori polypeptides. First, ORFs were analyzed for homology to other known output or membrane proteins. And analyzed by the discriminant analysis method described by Klein et al ((Klein, P., Kanehsia, M. and Delisi, C. (1985), Biophysica et Biophysica Acta, volume 815, page 468-476) to find the expected output and membrane proteins.

Homology searches can be performed using the BLAST algorithm contained in the Wisconsin Sequence Analysis Package (genetics computer Group, University Research Park,575, Science Drive, Madison, Wis 53711) to compare each expected ORF amino acid Sequence to all sequences currently found in the Genebank, SWISS-PROT and PIR databases. BLAST looks for a local match between the ORF and a database sequence and reports a likelihood score that indicates the chance of finding that sequence in the database. ORFs with significant homology to membrane or export proteins (e.g., the probability is preferably greater than 1X 10(ee-6) represent possible protein antigens for vaccine development based on sequence homology to genes cloned in other organisms, we can expect possible functions of H.pylori.

Discriminant analysis (Klein et al, supra) can be used to examine ORF amino acid sequences. This algorithm uses the intrinsic information contained in the ORF amino acid sequence and compares it with information obtained from the characteristics of known membranes and output proteins. This comparison would predict which proteins will be exported, bound to membranes or present intracellularly. The amino acid sequence of the ORF identified as output or membrane bound by this algorithm is likely to be the protein antigen for the development of a vaccine.

Surface exposed outer membrane proteins may represent the best antigens capable of providing a protective immune response against H.pylori. Algorithms that can be used to help predict these outer membrane proteins include the presence of an amphipathic B-fold region at the C-terminus. This region has been detected in a number of outer membrane proteins of gram-negative bacteria. This region is characterized by hydrophobic residues (Phe or Tyr) at approximately 1,3, 5, 7 and 9 positions from the C-terminus (see, e.g., FIG. 8, Module F). Importantly, these sequences were not detected in the periplasmic protein. This allows for a preliminary distinction between these protein families based on preliminary sequence data. This phenomenon has been previously reported by Struyve et al (journal of molecular biology 218, pp.141-148, 1991).

Also shown in FIG. 8 are additional amino acid sequence motifs found in many outer membrane proteins of H.pylori. The amino acid sequence listing in FIG. 8 describes the sequence portions (indicated by the one-letter amino acid codes) of the 12 H.pylori proteins, which are designated by their amino acid sequence ID numbers and are shown from N-terminus to C-terminus from right to left. The 6 different modules of similar amino acid residues (designated a to F) were found to contain a discriminating hydrophobic residue (Phe or Tyr, F or Y according to the one letter code of the amino acid residue) frequently occurring at a position near the C-terminus of the outer membrane protein. The presence of several common motifs clearly determines the similarity between the members of this family of proteins.

Furthermore, the outer membrane proteins isolated from H.pylori often carry motifs sharing a module of amino acid residues as shown in FIG. 9 near the mature N-terminus (i.e.after processing to remove the secretion signal peptide). FIG. 9 depicts the N-terminal part of the 9 H.pylori proteins (designated by their amino acid ID numbers, from left to right, showing N-terminal to C-terminal).

Those skilled in the art will appreciate that these common sequence motifs are of great significance and establish a similarity in this family of proteins.

In general, a plurality of possible nucleotides can be distinguished at a given position of a nucleotide sequence. In this case, the dual-relevance is represented by the following flat letter:

this is the common IUPAC-IUB one letter residue code

Base described by code

G-guanine

A adenine

T-Thymidine

C cytosine

R purine (A or G)

Y pyrimidine (C or T or U)

M amino (A or C)

K Ketone (G or T)

S Strong interaction (C or G)

W weak interaction (A or T)

H is not G (A or C or T)

B is not A (C or G or T)

V is not T (not U) (A or C or G)

D is not C (A or G or T)

N is any (A or C or G or T)

The amino acid translation of the present invention illustrates the double relationship in a nucleic acid sequence by translating the double relationship code into the letter X. In all cases, the allowed amino acid residues at a position are clear by examining the nucleic acid sequence based on standard genetic codes.

Preparation of fragments and analogues of H.pylori nucleic acids and polypeptides

Based on the findings of the helicobacter pylori gene products provided in the sequence listing, the person skilled in the art can make modifications to the disclosed structure (of the helicobacter pylori gene), for example, by preparing fragments or analogs and examining the activity of the resulting structure. Examples of techniques that are well known to those skilled in the relevant art and that can be used to prepare and detect fragments and analogs are discussed below, and these and similar methods can be used to prepare and screen libraries of polypeptides, such as random peptide libraries or libraries of fragments or analogs of cellular proteins that have the ability to bind helicobacter pylori polypeptides. This screening is useful for finding an inhibitor of helicobacter pylori.

Preparation of fragments

Fragments of a protein can be prepared by several methods, such as recombinant methods, digestion with proteases, or chemical synthesis. Internal or terminal fragments of a polypeptide can be prepared by removing one or more nucleotides from one end (preparing the terminal fragment) or both ends (preparing the internal fragment) of the nucleic acid encoding the polypeptide. The mutagenized DNA is expressed to produce polypeptide fragments. Digestion with "end-erosive" endonucleases can produce DNA encoding a series of fragments. DNA encoding protein fragments may also be prepared by random splicing, restriction digestion, or a combination of the methods discussed above.

Fragments can also be chemically synthesized using techniques well known in the art, for example, conventional Merrifield solid phase f-Moc or t-Boc chemistry. For example, the polypeptides of the invention can be arbitrarily divided into fragments of a desired length with no overlap of the fragments, or into overlapping fragments of a desired length.

Alteration of nucleic acids and polypeptides: stochastic method

Amino acid sequence variants of a protein can be prepared by random mutagenesis of DNA encoding the protein or a particular domain or region of the protein, using methods including PCR mutagenesis and saturation mutagenesis. Libraries of random amino acid sequence variants can also be prepared by synthesizing a degenerate set of oligonucleotide sequences (methods for screening proteins from a library of variants are described elsewhere herein).

(A) PCR mutagenesis

In PCR mutagenesis, Taq enzyme fidelity is reduced for introducing random mutations into cloned fragments of DNA (Leung et al, 1989, tech. 1, pp. 11-15). The DNA region to be mutagenized isamplified using the Polymerase Chain Reaction (PCR) under conditions which reduce the fidelity of the DNA synthesized by Taq DNA polymerase, e.g.using dGTP/dATP in a ratio of 5, and added in the PCR reaction . The mixed amplified DNA fragments are inserted into an appropriate cloning vector to provide a random mutation library.

(B) Saturation mutation

Saturation mutations allow rapid introduction of large numbers of single base substitutions into cloned DNA fragments (Mayers et al, 1985, science 229, page 242). This technique involves, for example, chemical treatment or irradiation of single-stranded DNA in vitro and synthesis of complementary DNA strands to generate mutations. The frequency of mutation can be adjusted by adjusting the degree of treatment, and substantially all possible base mutations can be obtained. Since this process does not involve genetic selection of the mutated segment, neutral substitutions as well as substitutions that alter function are available. The distribution of point mutations is not biased towards conserved sequence elements.

(C) Degenerate oligonucleotides

Homolog libraries can also be prepared from a degenerate set of oligonucleotide sequences. Chemical synthesis of degenerate sequences can be carried out on an automated DNA synthesizer, and the synthetic gene can then be ligated into an appropriate expression vector. The synthesis of degenerate oligonucleotides is well known in the art (see for example Narang, SA (1983) tetrahedron 39; Itakura et al (1981) recombinant DNA Advance, 3 rd Cleveland Association, Macromolecum, eds AG Walton, Amsterdam; Elsevier 273. sup. 289; Itakura et al (1984) annual review of biochemistry 53, 323; Itakura et al (1984) science 198, 1056; Ike et al (1983) nucleic acid research 11, 477). These techniques have been applied to directed evolution of other proteins (see, e.g., Scott et al (1990) science 249, 386-390; Roberts et al (1992) Proc. Natl. Acad. Sci. USA 89, 2429-2433; Devrin et al (1990) science 249 404-406; Cwirla et al (1990) Proc. Natl. Acad. Sci. 87, 6378-6382; and U.S. Pat. Nos.5,409,233, 5,198,346 and 5,096,815).

Alteration of nucleic acids and polypeptides: method for directed mutagenesis

Non-random or directed mutagenesis techniques can be used to provide mutagenesis of a particular sequence or region. These techniques can be used to prepare mutants comprising deletions, insertions or substitutions of residues of known amino acid sequences, such as proteins. The sites to be mutated may be modified individually or in series, for example by (1) first replacing with conservative amino acids and then performing the substitution with a more exhaustive selection based on the results obtained, (2) deleting the target base, or (3) inserting residues of the same or different families at adjacent sites, or a combination of options 1-3.

(A) Alanine scanning mutagenesis

Alanine scanning mutagenesis is a useful method for identifying the most preferred mutation position or region in a desired protein, Canning ham and Wells (science 244, 1081-1085, 1989). In an alanine scan, a residue or group of the target base is identified (e.g., charged residues such as Arg, Asp, His, Lys, and G1u) and replaced with a neutral or negatively charged amino acid residue (more preferably alanine or phenylalanine). A substitution of one amino acid can affect the interaction of the amino acid with the surrounding aqueous environment inside and outside the cell. The region that is shown to be susceptible to substitution is then refined by introducing further or other variations at the site of substitution or at the site to be substituted. Thus, when a site for introducing an amino acid sequence variation is predetermined, the nature of the mutation itself need not be predetermined. For example, to optimize performance of a mutation at a given site, alanine scanning or random mutagenesis can be performed at the target codon or region and the expressed desired protein subunit variants screened for the combination of the best desired activity.

(B) Oligonucleotide-mediated mutagenesis

Oligonucleotide-mediated mutagenesis is a useful method for making substitution, deletion and insertion mutants of DNA, see for example Adelman et al (DNA, Vol. 2, p. 183, 1983). Briefly, the desired DNA is altered by hybridization of an oligonucleotide encoding the mutation to a DNA template, which is a single-stranded form of a plasmid or phage containing the unaltered or native DNA sequence of the desired protein. After hybridization, a DNA polymerase is used to synthesize the entire second complementary strand of the template. The second complementary strand will incorporate the oligonucleotide primer and encode the desired change in the DNA of the desired protein. Generally, oligonucleotides of at least 25 nucleotides in length are used. The most preferred oligonucleotide has 12 to 15 nucleotides and is fully complementary to the template on either side of the nucleotide encoding the mutation. This ensures that the oligonucleotide is properly hybridized to the single-stranded DNA template molecule. Oligonucleotides can be conveniently synthesized by techniques well known in the art, such as those described by Crea et al (Proc. Natl. Acad. Sci. USA, Vol. 75, p. 5765 (1978)).

(C) Cassette mutagenesis

Another method for preparing variants is cassette mutagenesis, based on the technique described by Wells et al (Gene 34, page 315 (1985)), starting from a plasmid (or other vector) containing the subunit DNA of the protein to be mutated. The codons to be mutated in the protein subunit DNA are determined. There must be a single restriction site on each side of the defined mutation site. If no such restriction sites are present, they must be introduced at the appropriate sites in the desired protein subunit DNA using the oligonucleotide-mediated mutagenesis approach described above. After restriction sites have been introduced into the plasmid, the plasmid is linearized by cleaving at these sites. Double-stranded oligonucleotides encoding DNA sequences between the two restriction sites but containing the desired mutagenesis were synthesized using standard techniques. The two strands are synthesized separately and then hybridized together using standard techniques. This double-stranded oligonucleotide is called a cassette. This cassette is designed to have 3 'and 5' ends that match the ends of the linearized plasmid so that it can be directly ligated to the plasmid. The plasmid now contains the mutated desired protein subunit DNA sequence.

(D) Combinatorial mutagenesis

Combinatorial mutagenesis may also be used to generate mutants (Ladner et al, WO88/06630) in which a set of amino acid sequences of homologues or other related proteins are aligned, preferably to increase the highest homology possible. All amino acids occurring at a given position of the listed sequences are selected to produce a degenerate set of combinatorial sequences. A variegated library of variants was prepared using combinatorial mutagenesis at the nucleic acid level and was encoded by a variegated gene library. For example, a mixture of synthetic oligonucleotides can be enzymatically linked to a gene sequence, thereby allowing a degenerate set of possible sequences to be expressed as a single peptide. Alternatively, it is expressed as a set of larger fusion proteins containing the set of concatemeric sequences.

Additional modification of helicobacter pylori nucleic acids and polypeptides

The structure of a H.pylori polypeptide can be modified for purposes such as increased solubility, increased stability (e.g., increased in vitro longevity and resistance to proteases in vivo). Helicobacter pylori protein or polypeptide whose amino acid sequence has been modified, for example, by substitution, deletion or addition of the amino acids described herein, can be prepared.

The H.pylori polypeptide may also be modified by substituting cysteine residues to reduce disulfide bond-forming dimers, preferably with alanine, serine, threonine or glutamic acid residues, and, in addition, the amino acid side chains of the protein fragments of the present invention may also be chemically modified. Another modification is cyclization of the peptide.

To increase stability and/or reactivity, the H.pylori polypeptide may be modified by including one or more polymorphisms in the amino acid sequence of the protein resulting from any natural allelic variation. Furthermore, within the scope of the present invention, D-amino acids, unnatural amino acids, or non-amino acid analogs can be substituted or added to prepare modified proteins. Furthermore, helicobacter pylori polypeptides may also be modified with polyethylene glycol (PEG) according to the methods of a.sehon and co-workers (Wie et al supra) to prepare PEG conjugated proteins. In addition, PEG may be added during the chemical synthesis of the protein. Other modifications of H.pylori proteins include reduction/alkylation (Tarr, methods for protein microanalysis, edited by J.E.silver, Humana Press, Clifton NJ 155-.

To facilitate purification and to increase the solubility of the H.pylori protein or peptide as much as possible, an amino acid fusion moiety may be added to the peptide backbone. For example, 6-histidine can be added to the protein for purification by immobilized metal ion affinity chromatography (Hochuli, E.et al (1988) Bio/technology 6, 1321-. In addition, to facilitate isolation of peptides that do not contain unrelated sequences, specific endoprotease cleavage sites can be introduced between the fusion moiety and the peptide.

To aid as much as possible in the proper antigenic processing of epitopes within H.pylori polypeptides, standard protease-sensitive sites can be introduced between the regions by genetic engineering, either recombinantly or synthetically, to contain at least one epitope each. For example, charged amino acid pairs, such as KK or RR, can be introduced between regions of a protein or fragment during recombinant construction. The resulting peptide will be susceptible to cleavage by cathepsin or other trypsin-like enzymes, resulting in a protein portion containing one or more epitopes. In addition, such charged amino acid residues may increase the solubility of the peptide.

Primary method for screening polypeptides and analogs

Various methods are known in the art for screening the resulting mutant gene products. Techniques for screening large numbers of gene libraries typically involve cloning the gene library into a replicable expression vector, transforming appropriate cells with the resulting library of vectors, and expressing the gene under conditions in which the desired activity is detected to facilitate isolation of the vector encoding the product gene detected, e.g., in this case, binding to a helicobacter pylori polypeptide or an interacting protein. Each of the techniques described below can be adapted for high throughput analysis of screening large numbers of sequences, for example, generated by random mutagenesis techniques.

(A) Two-hybrid system

Two-hybrid assays, such as the systems described above (e.g., other screening methods described herein), can also be used to identify polypeptides, such as naturally-occurring H.pylori polypeptides, e.g., cellular proteins, or fragments or analogs of randomly-generated polypeptides that bind to H.pylori protein. (the H.pylori domain is used as bait protein and the variant library is expressed as fish fusion protein), similarly, the two-hybrid assay (in contrast to the other screening methods described herein) can be used to find polypeptides that bind to H.pylori polypeptides.

(B) Displaying libraries

In a screening assay, candidate polypeptides are displayed on the surface of a cell or viral particle, and the ability of a particular cell or viral particle to bind to the appropriate receptor protein via the displayed product can be detected using a "panning assay". For example, a gene library can be cloned into a gene encoding a surface membrane protein of a bacterial cell, and the resulting fusion protein detected by panning (Ladner et al, WO 88/06630; Fuchs et al (1991) Bio/technology 9, 1370-. Similarly, a detectably labeled ligand can be used to evaluate polypeptide homologs that may be functional. Fluorescently labeled ligands such as receptors can be used to detect homologs that retain ligand binding activity. The use of fluorescently labeled ligands allows cells to be visualized and isolated under a fluorescent microscope or by a fluorescence activated cell sorter under conditions that cellular morphology permits.

A gene library can be expressed as a fusion protein on the surface of a viral particle. In filamentous phage systems, for example, the foreign peptide sequence can be expressed on the surface of infectious phage, which has two distinct advantages. Firstly, the phage can be far more than 10 per ml¹³The concentration of phage is added to the affinity matrix so that a large number of phage can be screened at one time. Second, since each infectious phage displays a gene product on the surface, if the yield of a particular phage recovered fromthe affinity matrix is low, the phage can be amplified with another round of infection. Almost identical E.coli filamentous phages M13, fd and f1 families were most commonly used in phage display libraries. Either phage gIII or gVIII capsid proteins can be used to generate fusion proteins without disrupting the final packaging of the viral particles. Exogenous epitopes expressible in pIII At the end, phage carrying such an epitope are recovered from a very large number of phage lacking the epitope (Landner et al, PCT publication, WO 90/02909; Garrrard et al, PCT publication)WO 92/09690; mark et al, (1992) journal of biology and chemistry 267 Vol, 16007-16010; griffhs et al (1993) EMBOJ 12 Vol 725-734; c1ackson et al (1991) Nature 352 Vol.624-; barbas et al (1992) Proc. Natl. Acad. Sci. USA 89 Vol. 4457 and 4461).

One common method uses the E.coli maltose receptor (outer membrane protein, LamB) as a peptide fusion partner (Charbit et al, (1986), EMBO J. 5, 3029-3037). Oligonucleotides were inserted into the plasmid encoding the LamB gene to generate peptides fused to one extracellular loop of the protein. These peptides can be used to bind ligands, such as antibodies, and elicit an immune response upon inoculation of the cells into an animal. Other cell surface proteins, such as OmpA (Schorr et al (1991) vaccine 91, 387-392), PhoE (Agterberg et al (1990) Gene 88, 37-45) and PAL (Fuchs et al (1991) Bio/technology 9, 1369-1372) and large bacterial surface structures have been used as vectors for peptide display. Peptides can be fused into pilin, a protein that polymerizes to form pilus channels for the exchange of genetic information between bacteria (Thiry et al (1989) applied and environmental microbiology 55 vol.984,993). Because of its role in interacting with other cells, pili can provide useful support for displaying polypeptides in the extracellular environment. Another large surface structure that can be used for peptide display is the bacterial motor organ, a flagellum. Fusion of peptides to flagellin subunits can produce a dense arrangement of many copies of the peptide on the surface of the host cell (Kuwajima et al Bio/technology volume 6, page 1080-1083). Surface proteins of other bacterial species may also be used as peptide fusion partners. Examples include staphylococcal protein A and IgA, the outer membrane protein membrane of Statherobacter (Hansson et al (1992) journal of bacteriology 174, 4239. sup. + 4245 and Klauser et al (1990) EMBO J9, 1991. sup. + 1999).

In the filamentous phage system and the LamB system described above, the physical association of a peptide with its encoding DNA is that the DNA is contained in a particle (cell or phage) that carries the peptide on its surface. The capture peptide is the capture particle and its bound DNA. Another approach uses the DNA binding protein Lac I to form a link between peptide and DNA (Cull et al (1992) Proc. Natl. Acad. Sci. USA 89, 1865, 1869). This system uses a plasmid containing the Lac I gene and having an oligonucleotide cloning site at its 3' end. Under controlled arabinose induction, a LacI-peptide fusion protein was produced. This fusion protein retains the native binding ability of LacI to a short DNA sequence called the LacO promoter (LacO). The LacI-peptide fusion protein was tightly bound to the plasmid encoding it by mounting two copies of LacO on the expression plasmid. Since the plasmid contains only a single oligonucleotide sequence per cell and each cell expresses only a single peptide sequence, the peptide is thus specifically and stably associated with the DNA sequence directing its synthesis. The cells of the library are gently lysed and the peptide-DNA complexes are contacted with a matrix having immobilized receptors to recover the complexes containing the active peptides. The bound plasmid DNA is then reintroduced into the cells for amplification and the DNA sequence is sequenced to identify the peptide ligands. As a practical demonstration of this approach, we prepared a large random dodecapeptide library and screened on a monoclonal antibody generated with the opioid peptide dynorphin B. A panel of peptides was recovered, all linked to a consensus sequence corresponding to the 6-residue portion of dynorphin B (Cull et al (1992) Proc. Natl. Acad. Sci. USA 89, 1869).

This approach, sometimes referred to as peptide on plasmid, differs from phage display technology in two important respects. First the peptide is attached to the C-terminus of the fusion protein, resulting in members of the library appearing as peptides with free carboxy termini. Both filamentous phage capsid proteins pIII and pVIII are anchored to the phage by their C-termini, while the foreign peptide is placed in the outward N-terminal domain. In some designs, the peptide displayed by the phage is present at the amino terminus of the fusion protein (Cwirla et al, (1990) Proc. Natl.Acad.Sci. USA 87, 6378-6382). The second difference is that the setting of biological bias affects the number of peptide populations actually present in the pool. The LacI fusion molecule is confined in the cytoplasm of the host cell. The phage capsid fusion proteins are, in turn, transiently exposed to the cytoplasm during translation, but are quickly secreted into the periplasmic cavity through the inner membrane, leaving only their C-terminal hydrophobic domain anchored to the membrane, with the N-terminus containing the peptide extending into the periplasm, ready for installation into the phage particle. There was a clear difference between LacI and the peptides in the phage library due to their exposure to different protease activities. The phage capsid proteins need to be transported across the inner membrane and signal peptidase processing is required as a prelude to integration into the phage. Certain peptides can have deleterious effects on these processes and are present in low numbers in the library (Callop et al (1994) journal of medical chemistry 37 (9), 1233-. These particular biases are not a factor in LacI display systems.

The number of small peptides available in recombinant random pools is enormous. Preparation generally 10⁷-10⁹Libraries of independent clones. Has been prepared to have a size of 10¹¹Libraries of recombinants, but this size is close to the practical limit of clonal libraries. This restriction of library size results from the step of transforming the DNA containing the randomized fragment into the host bacterial cell. To overcome this limitation, an in vitro system based on the display of nascent peptides in a multimeric ribosomal complex has recently been developed. This display method has the ability to produce libraries 3-6 orders of magnitude larger than the phage/phagemid or plasmid libraries currently available. Moreover, the construction of the library, the expression and screening of the peptides are entirely cell-freeThe method is carried out.

In one application of this method (Gallop et al (1994) journal of medical chemistry 37 (9), pages 1233-¹²A library of ten-peptide molecular DNA, which was expressed in an E.coli S30 in vitro coupled transcription/translation system. The conditions are selected to retain the ribosomes on the mRNA, allow a substantial portion of the RNA to accumulate in the polysome, and produce a nascent peptide complex that comprises the RNA still associated with its coding sequence. Polysomes are sufficiently stable to allow affinity purification on immobilized receptors in the same manner as screening in more traditional recombinant peptide display libraries. The RNA is recovered from the bound complex, converted to cDNA, and amplified by PCR to prepare the template for the next round of synthesis and screening. The polysome display technology can be coupled with a phage display system,and after several rounds of screening, cDNA from the enriched mixture of polysomes is cloned into a phagemid vector. The vector can be used as a peptide expression vector to display a peptide fused with capsid protein, and can also be used as a DNA sequencing vector to identify the peptide. By expressing polysome-derived peptides on phage, we can use this model to continue the affinity selection procedure, or to test the binding activity of peptides on individual clones in phage ELISA, or to test the binding specificity in a stopped phage ELISA (Barret et al, (1992) Ann. Rev. biochem. 204, p. 357-364). To identify the sequence of the active polypeptide, we sequenced the DNA produced by the phagemid.

Secondary screening of polypeptides and analogs

The high throughput assay described above may be followed by a secondary screen to identify further biological activities, which may allow one skilled in the art to distinguish between agonists and antagonists, for example. The type of secondary screening used will depend on the desired activity to be detected. For example, an assay can be developed in which the ability to inhibit the interaction of a protein moiety of interest with its corresponding ligand can be used to identify antagonists from a panel of polypeptide fragments isolated from the primary screen described above.

Thus, methods for making fragments and analogs and for assaying their activity are well known in the art. Once the core sequence of interest is identified, analogs and fragments can be routinely obtained by one skilled in the art.

Peptide mimetics of helicobacter pylori polypeptides

The invention also provides for the reduction of the protein binding region of the helicobacter pylori polypeptide of the invention to prepare mimetics, e.g., peptide or non-peptide agents. Peptide mimetics are capable ofdisrupting the binding of a polypeptide to its ligand, for example when a helicobacter pylori polypeptide binds to its naturally occurring ligand. Key residues of the H.pylori polypeptides of the invention which are involved in the molecular recognition of the polypeptide can be determined and used for the preparation of H.pylori-derived polypeptide mimetics which competitively or non-competitively inhibit the binding of the H.pylori polypeptide to a polypeptide with which it interacts (see, for example, European patent applications EP-412,762A and EP-B31,080A).

For example, scanning mutagenesis can be used to map amino acid residues of a particular H.pylori polypeptide involved in binding to an interacting polypeptide, and peptidomimetic compounds (e.g., diazepine or isoquinoline derivatives) can be prepared which mimic the residues bound to the interacting polypeptide and thereby inhibit binding of the H.pylori polypeptide to the interacting polypeptide, thereby interfering with the function of the H.pylori polypeptide, for example, non-hydrolyzable peptide analogs of these residues can be prepared using benzodiazepines (see, e.g., Freidinger et al, peptides; chemistry and biology, G.R.Marshall editor, ESCOM, Leiden, Netherlands,1988), nitrogen weeds (see, e.g., Huffman et al, peptides; chemistry and biology, G.R.Marshall, ESpublication, Leiden, Netherlands,1988), substituted γ -lactam loops (Garvey et al, peptides; chemistry and biology, Marshall, Inc. J.1988, 1988), peptides of the chemistry and Biochefferson, Inc., see, Inc., Checker et al, Inc., 1985, 1988), Biote, Inc., peptide, Inc., 1988, Inc., see, Inc., 1985, Inc., 1988, Inc., and U.S.g. 9, 1988, Inc., 1988, et al, 1988, for the journal of chemical and U.g. for the discussion, for the discussion of chemical and Biote, Inc., peptide, Inc., see, Inc., for the discussion, Inc., see, Inc., U.S.S.S.S. for the discussion, 1985, 1988, et al, for the discussion, 1988.

VI vaccine preparation of pylorus helicobacterium polypeptide and nucleic acid

The present invention also details vaccine compositions for protecting against or treating helicobacter pylori infection, which is a gram-negative helical microaerophilic bacterium. In one embodiment, the vaccine composition comprises one or more immunogenic components from helicobacter pylori, such as a surface protein or a portion thereof, and a pharmaceutically acceptable carrier. Examples of nucleic acids within the scope of the present invention are the nucleic acids shown in the sequence listing which code for the helicobacter pylori surface protein. However, any nucleic acid encoding an immunogenic H.pylori protein or a fragment thereof and capable of being expressed in a cell can be used in the present invention. These vaccines have therapeutic or prophylactic use.

One aspect of the present invention provides a vaccine composition for providing protection against helicobacter pylori infection, comprising at least one immunogenic fragment of helicobacter pylori protein, and a pharmaceutically acceptable carrier. Preferred fragments include peptides of at least about 10 amino acid residues in length, more preferably about 10-20 amino acid residues in length, and even more preferably about 12-16 amino acid residues in length.

The immunogenic components of the invention can be obtained, for example, by screening recombinantly produced polypeptides from the corresponding fragments of nucleic acids encoding full-length helicobacter pylori protein. In addition, fragments can be chemically synthesized using techniques well known in the art, such as conventional Merrifield solid phase f-Moc or t-Boc chemistry.

In one embodiment, the immunogenic component is identified by the ability of a periceptide to stimulate T cells, as determined by, for example, T cell proliferation or cytokine secretion, and a peptide capable of stimulating T cells is defined herein as containing at least one T cell epitope. T cell epitopes are believed to be involved in the initiation and persistence of the immune response to protein allergens, which cause the clinical symptoms of allergy. These T cell epitopes may trigger early events at the T helper cell level by binding to appropriate HLA molecules on the surface of an antigen presenting cell, and then stimulate a subpopulation of T cells having epitope-associated T cell receptors. These events lead to T cell proliferation, lymphokine secretion, local inflammatory responses, and the initiation of other immune cell to site of antigen/T cell interaction, as well as the activation of B cell cascades, leading to the production of antibodies. A T cell epitope is an essential element or minimal unit of T cell receptor recognition, and an epitope contains amino acids (e.g., about 6 or 7 amino acid residues) that are essential for receptor recognition. Amino acid sequences that mimic T cell epitopes are also within the scope of the invention.

In another embodiment, the immunogenic components of the invention are identified by genomic vaccination. The basic method is based on the idea that an expression library consisting of all or part of the genome of an antigen, such as the H.pylori genome, can provide protection when used for the genetic immunization of a host. This Expression Library Immunization (ELI) is similar to expression cloning and involves the introduction of a genomic expression library of a pathogen, such as helicobacter pylori, into a plasmid capable of serving as a genetic vaccine. Plasmids can also be designed to encode genetic adjuvants that significantly stimulate humoral responses. These genetic adjuvants can be introduced at remote sites, acting extracellularly as well as intracellularly.

This is a new method for the preparation of vaccines with the many advantages of live/attenuated pathogens without the risk of infection. The expression library of pathogen DNA is used to immunize a host, and the resulting live vaccine is effective for antigen presentation without risk. For example, in the present invention, random fragments from H.pylori genomic or cosmid or plasmid clones, as well as PCR products from genes identified by genomic sequencing, can be used to immunize a host. The feasibility of this approach has been demonstrated with Mycoplasma pneumoniae (Barry et al, Nature 377, 632-635, 1995), which is a natural pathogen in rodents, where even partial expression libraries of Mycoplasma pneumoniae provide protection against pathogen attack.

ELI technology allows for the preparation of non-infectious multivalent vaccines, even when little is known about the biology of the pathogen, since ELI uses the immune system to screen candidate genes. Once isolated, these genes can be used as genetic vaccines or to develop recombinant protein vaccines. ELI thus allows vaccines to be produced in a systematic, large-scale, mechanized manner.

Screening for immunogenic components can be accomplished using one or more different assays. For example, in vitro, the T cell stimulatory activity of a peptide is assayed by contacting a peptide known or suspected to be immunogenic with an antigen presenting cell capable of presenting a suitable MHC molecule in a T cell culture. Presentation of immunogenic H.pylori peptides bound to suitable MHC molecules to T cells in combination with the necessary co-stimulation enables transmission of signals to the T cells and triggers an increase in the levels of cytokines, particularly interleukin-2 and interleukin-4. Culture supernatants may be harvested and analyzed for interleukin-2 or other known cytokines, for example, any of several conventional interleukin-2 assays may be used. Such as those described in the relevant section of Proc. Natl.Acad.Sci.USA 86, 1333 (1989), which is hereby incorporated by reference. The interferon production can also be analyzed using the Genzyme Corporation (Cambridge, MA) assay kit.

In addition, a common assay for T cell proliferation requires detection of incorporation of tritiated thymine. Proliferation of T cells can be measured in vitro³H-labeled thymine is integrated into the amount of replicating DNA of cultured cells. Thus, the rate of DNA synthesis and the rate of cell division can be measured.

The vaccine compositions of the present invention comprising an immunogenic component, such as a helicobacter pylori polypeptide or a fragment thereof or a nucleic acid encoding a helicobacter pylori polypeptide or a fragment thereof, preferably comprise a pharmaceutically acceptable carrier. The term "pharmaceutically acceptable carrier" refers to a carrier that does not cause an allergic response or other undesirable effect in the patient to whom it is administered. Suitable pharmaceutically acceptable carriers include, for example, one or more of water, saline, phosphate buffered saline, dextrose, glycerol, ethanol, and the like, and combinations thereof. The pharmaceutically acceptable carrier may further include minor amounts of auxiliary substances such as wetting or emulsifying agents, preservatives or buffers, which enhance the shelf life or effectiveness of the antibody. For the vaccine of the present invention comprising a helicobacter pylori polypeptide, the polypeptide is administered with a suitable adjuvant.

It will be apparent to those skilled in the art that a therapeutically effective amount of a DNA or protein of the invention will depend, inter alia, on the administration procedure, the unit dose of antibody administered, whether the protein or DNA is administered with other therapeutic agents, the immune status and health of the patient, and the therapeutic activity of the particular protein and DNA.

Vaccine compositions are typically administered parenterally, for example by injection, subcutaneously or intramuscularly. Methods of intramuscular immunization are described by Wolff et al (1990) science 247, 1465-. Other modes of administration include oral or pulmonary inhalation formulations, suppositories, and dermal administration. Oral immunization is preferred over parenteral administration in terms of inducing protection against H.pylori. Czinn et al (1993) vaccine 11 Vol 637-642. Oral formulations include commonly used excipients such as pharmaceutical grades of mannitol, lactose, starch, magnesium stearate, sodium saccharin, cellulose, magnesium carbonate, and the like.

The vaccine composition of the invention may include an adjuvant including, but not limited to, aluminum hydroxide, N-acetyl-muramyl-L-threonyl-D-isoglutamine (thr-MDP), N-acetyl-N-muramyl-L-alanyl-D-isoglutamine (CGP11637, referred to as N-MDP), N-acetyl-L-alanyl-D-isoglutamyl-L-alanine-2- (1 ', 2' -dipalmitoyl-sn-glycero-3-hydroxyphosphoryl-phoryloxy) -ethylamine (CGP19835A, referred to as MTP-PE), RIBI, which contains three components from bacteria: monophosphoryl A, trehalose dimycolate, cell wall matrix (MPL + TDM + CWS) dissolved in 2% squalene/Tween 80, and cholera toxin. Other non-toxic derivatives of cholera toxin including its B subunit and/or conjugates of H.pylori with cholera toxin or its B subunit or genetically engineered fusion proteins, prodholeragenid, fungal polysaccharides including plectan, muramyl dipeptide derivatives, phorbol esters, E.coli labile toxins, non-H.pylori bacterial lysates, block polymers or saponins may be used.

Other suitable delivery methods include biodegradable microcapsules or Immune Stimulating Complexes (ISCOMs) or liposomes, genetically engineered live attenuated vectors such as viruses or bacteria, and recombinant (chimeric) virus-like particles, such as bluetongue virus. The amount of adjuvant used depends on the type of adjuvant used. For example, when the mucosal adjuvant is cholera toxin, a dose of 5 μ g to 50 μ g, e.g. 10 μ g to 35 μ g, is suitably used. When used in microencapsulated form, the dosage will depend on the amount applied to achieve the desired dosage in the microcapsule matrix. Determination of such a dose is within the ability of one of ordinary skill in the art.

The carrier system of the human body may comprise enteric-release capsules to protect the antigen in the acidic environment of the stomach, including inclusion of the helicobacter pylori polypeptide in an insoluble form of the fusion protein, suitable carriers for the vaccine of the invention being enteric-coated capsules and polylactide-glycotide microspheres. Suitable diluents are 0.2N And/or saline.

The vaccines of the present invention may be administered as a primary prophylactic agent in adults or children, or as a secondary defense after successful eradication of H.pylori in an infected host, or as a therapeutic agent for the purpose of inducing an immune response in susceptible recipients to prevent H.pylori infection. The vaccines of the present invention are administered at dosages that can be readily determined by one of ordinary skill in the art. Thus, a suitable dose for an adult is in the range 10 μ g to 10g, preferably 10 μ g to 100mg, for example 50 μ g to 50 mg. For adults, suitable doses may also be in the range of 5 μ g to 500 mg. Similar dosage ranges are also applicable to children. It will be appreciated by those skilled in the art that the optimum dosage may be increased or decreased depending on the weight of the patient, the disease, the route of administration and other factors. It will also be appreciated by those skilled in the art that suitable dosage levels may be obtained based on results from known oral vaccines, such as,for example, E.coli lysate based vaccines (6 mg per day to a total of 540mg), and E.coli-enterotoxic purified antigen (1mg,4 doses) (Schulman et al, JUrol. 150, page 917; 921 (1993); Boedecker et al, American scientific research asset.999: A-222 (1993)). The number of doses is based on the disease, prescription and efficacy data from clinical trials. Without limiting the course of treatment, treatment may be given in 3 to 8 doses over a month for priming (Boedeker et al, American scientific Assoc.888: A-222 (1993)).

It will be apparent to those skilled in the art that certain vaccine compositions of the present invention are useful only for the prevention of H.pylori infection, some are useful only for the treatment of H.pylori infection, and some are useful for both the prevention and treatment of H.pylori infection. In a preferred embodiment, the vaccine composition of the present invention provides protection against H.pylori infection by activating humoral and/or cell-mediated immunity against H.pylori. It will be appreciated that alleviation of any symptoms of H.pylori infection is a desirable clinical objective, including reduction of the amount of pharmaceutical agents used to treat H.pylori-induced disease.

Antibodies reactive with helicobacter pylori polypeptides

The invention also includes antibodies that specifically react with the helicobacter pylori polypeptides of the invention. Antisera or monoclonal antibodies to the protein/anti-peptide can be prepared by standard methods (see, e.g., antibodies, laboratory manuals, Harlow and Lane, ed. (Cold spring harbor published, 1988.) A mammal, such as a mouse, hamster, or rabbit, can be immunized with an immunogenic form of the peptide.

In a preferred embodiment, the antibody of the invention is immunospecific for an epitope of a polypeptide of the invention which is as set forth in the sequencelisting or of a closely related human or non-human mammalian homolog (e.g., 90% homologous, more preferably at least 95% homologous). In a more preferred embodiment of the invention, the anti-H.pylori antibody does not substantially cross-react (i.e.specifically react) with proteins having a homology of less than 80% to, for example, the sequences shown in the sequence listing. By "substantially non-cross-reactive" is meant that the binding affinity of the antibody to the non-homologous protein is less than 10%, more preferably less than 5%, more preferably less than 1% of the binding affinity to the proteins contained in the sequence listing. In a more preferred embodiment, there is no cross-reactivity between bacterial and mammalian antigens.

The term antibody as used herein includes fragments thereof which are still capable of specifically reacting with a H.pylori polypeptide. The antibody may be fragmented by conventional techniques and may be fragments selected for use in the same manner as the whole antibody described above. For example, F (ab')₂Fragments can be prepared by treating the antibody with trypsin. The resulting F (ab')₂The fragments can be used to prepare Fab' fragments via reduction of disulfide bonds. The antibodies of the invention also include bispecific and chimeric molecules having an anti-helicobacter pylori moiety.

Monoclonal and polyclonal antibodies (Ab) directed against helicobacter pylori polypeptides or helicobacter pylori polypeptide variants, and antibody fragments such as Fab 'and F (Ab')₂Can be used for blocking the action of helicobacter pylori polypeptide by microinjecting the anti-helicobacter pylori polypeptide antibody of the present invention, and studying the abnormal or harmful effects of the specific helicobacter pylori polypeptide of the present inventionIntracellular signaling and normal H.pylori cell function.

Antibodies that specifically bind to an epitope of H.pylori can also be used for immunohistochemical staining of tissue samples to assess the abundance and profile of H.pylori antigen expression. Antibodies against helicobacter pylori polypeptides can be used diagnostically in immunoprecipitation and immunoblotting as part of a clinical testing procedure to detect and assess levels of helicobacter pylori in tissues or body fluids. Similarly, the ability to monitor the level of H.pylori polypeptide in an individual can be used to determine the effect of a given treatment regimen on individuals afflicted with the disease. The level of helicobacter pylori polypeptide may be detected in cells found in a body fluid, such as a urine sample, or in tissue, such as tissue prepared from a gastric biopsy. Diagnostic assays using anti-H.pylori antibodies can include, for example, immunoassays designed to aid in the early diagnosis of H.pylori infection. The present invention can also use a specific helicobacter pylori antigen as an antibody for detecting an antibody contained in a sample from an individual infected with such bacteria.

Another application of the anti-H.pylori polypeptide antibodies of the invention is in immunoscreening of cDNA libraries constructed in expression vectors such as lambda gt11, lambda gt18-23, lambda ZAP and lambda ORF 8. messenger libraries of this type have correctly inserted open reading frames and correctly oriented coding sequences which can be used to prepare fusion proteins.e.g.lambda gt11 can prepare fusion proteins whose amino terminus consists of the β -galactosidase amino acid sequence and whose carboxyl terminus consists of a foreign polypeptide.

Kit containing nucleic acid, polypeptide or antibody of the invention

The nucleic acids, polypeptides and antibodies of the invention may be combined with other reagents and materials to form a kit. Kits for diagnostic purposes generally contain nucleic acids, polypeptides, or antibodies in small tubes or other suitable containers. The kit typically contains reagents, such as aqueous media, salts, buffers, etc., for performing hybridization reactions, Polymerase Chain Reactions (PCR), or reconstitution of lyophilized components. The kit may also contain reagents for sample processing, such as detergents, chaotropic salts, etc. The kit may further comprise immobilization means such as particles, supports, wells, dipsticks, and the like. The kit may further comprise labeling means such as dyes, chromogenic reagents, radioisotopes, fluorescent reagents, luminescent or chemiluminescent reagents, enzymes, intercalating agents, and the like. Based on the nucleic acid and amino acid sequence information provided herein, one skilled in the art can readily assemble kits for their particular purpose, which kits can further include instructions for use.

IX drug screening assay Using helicobacter pylori Polypeptides

By preparing purified and recombinant helicobacter pylori polypeptides which are available, the present invention provides drug screening assays which can be used for agonists or antagonists of normal cell function, here the helicobacter pylori polypeptides of the present invention, or their role in intracellular signaling. Such inhibitors or potentiators are useful as novel therapeutic agents for combating helicobacter pylori infection in humans. A variety of test protocols are satisfactory and will be appreciated by the skilled artisan in light of the present disclosure.

In many drug screening programs that test libraries of compounds and natural extracts, high throughput assays are required to maximize the number of compounds detected in a given time. Experiments performed in cell-free systems, such as systems from purified or semi-purified proteins, are commonly referred to as "primary screens," and can be usedto rapidly and relatively easily detect changes in molecular targets mediated by test compounds. Moreover, the effects of cytotoxicity and bioavailability of test compounds are generally negligible in vitro systems, and tests have focused primarily on the effects of drugs on molecular targets, as evidenced by changes in the binding affinity of the molecular target to other proteins or changes in enzymatic characteristics. Accordingly, in an exemplary screening assay of the invention, a compound of interest is contacted with an isolated or purified H.pylori polypeptide.

Screening assays can be established in vitro using a purified H.pylori polypeptide or a fragment thereof, e.g., a H.pylori polypeptide having enzymatic activity, such that the activity of the polypeptide produces a detectable reaction product. The effect of a compound can be assessed using dose-response curves obtained from data using different concentrations of the test compound. Furthermore, control tests may also be performed to provide a comparative baseline. Suitable products include, for example, those having distinguishable light absorption, fluorescence or chemiluminescence properties, since detection can be conveniently automated. A variety of synthetic or naturally occurring compounds can be tested in assays to identify those compounds that are capable of inhibiting or enhancing the activity of a helicobacter pylori polypeptide. Some of these active compounds may also inhibit or enhance the same activity (e.g.enzyme activity) in intact living H.pylori cells, either directly or by chemical modification to increase membrane permeability or solubility.

The invention is further illustrated by the following examples, which are not to be construed as limiting. The contents of all referenced and published patent applications cited in this application are hereby incorporated by reference.

Other embodiments

Many nucleic acids and corresponding polypeptides of the invention have been previously disclosed in the following patent applications: U.S.S.N.08/761,318,1996, 12/6 (attorney docket No.: GTN-009CP 2); U.S.S.N.08/736,905,1996, 25/10 months (attorney docket No.: GTN-010 CP); U.S.S.N.08/738,859,1996, 10 month, 28 day submission (attorney docket No.: GTN-009 CP); they were part of a continuation-in-progress application submitted on day 3/29 of U.S. S.S. N.08/625,811,1996 (attorney docket No.: GTN-009) and on day 4/2 of U.S. S.S. N.08/758,731,1996 (attorney docket No.: GTN-010). The comparison between the serial numbers in the above-mentioned patent application and the serial numbers provided herein is set forth in table 7 below.

TABLE 7

ORF names	Origin of origin	Pronucleoside Sequences of Number (C)	Ortho-amino group Sequences of Number (C)	CIPI nucleus Nucleotide sequence Column number	CIPI Ammonia Sequence of the base Column number	Current nucleus Nucleotide sequence Column number	Current ammonia Sequence of the base Column number
								01ae12021orf5	009CP1	5	867	3	1095	1	492
01ce10516orf15	009CP1	15	877	10	1102	2	493
								01ce10516orf19	009CP1	18	880	13	1105	3	494
01ce10516orf20	009CP1	19	881	14	1106	4	495
								01ce10516orf21	009CP1	20	882	15	1107	5	496
01ce10516orf24	009CP1	21	883	16	1108	6	497
								01ce11618orf24	009CP1	36	898	30	1122	7	498
01ce11618orf3	009CP1	37	899	31	1123	8	499
								01ce11513orrf17	010CP1	44	1957	35	1554	9	500
01cp11414orf2	009CP1	44	906	36	1128	10	501
								01cp11710orf1	009CP1	46	908	37	1129	11	502
01ce11618orf1	010CP1	51	1964	38	1557	12	503
								01ce11618orf13	010CP1	54	1967	40	1559	13	504
01ep11504orf5	009CP1	65	927	52	1144	14	505
								01ep30520orf24	009CP1	67	929	54	1146	15	506
01cp11108orrf6	010CP1	74	1987	54	1573	16	507
								01gp11016orf13	009CP1	78	940	63	1155	17	508
02ae11612orf1	009CP1	97	959	79	1171	18	509
								02ae11612orf15	009CP1	99	961	80	1172	19	510
01ep30520orf8	010CP1	121	2034	86	1605	20	511
								02ap21113orf2	009CP1	112	974	88	1180	21	512
02ap21220orf2	009CP1	114	976	90	1182	22	513
								01ge10801orf2	010CP1	133	2046	91	1610	23	514

02ce10213orf19	009CP1	116	978	92	1184	24	515
								02ce10216orf6	009CP1	123	985	96	1188	25	516
02ce10216orf7	009CP1	124	986	97	1189	26	517
								02ce10809orf6	009CP1	130	992	103	195	27	518
04ce11617orf27	001CP7	1087	1538	119	372	28	519
								02ep30607orf27	009CP1	158	1020	120	1212	29	520
029e20116orf25	009CP1	164	1026	125	1217	30	521
								02ae21214orf1	010CP1	193	2106	129	1648	31	522
03ap21820orf4	009CP1	181	1043	139	1231	32	523
								03ap21820orf8	009CP1	183	1045	141	1233	33	524
02ce10114orf3	010CP1	206	2119	142	1661	34	525
								03ce21717orf1	009CP1	186	1048	144	1236	35	526
039p20123orf3	009CP1	196	1058	152	1244	36	527
								02cc10216orf4	010CP1	225	2138	152	1671	37	528
03xe11215orf7	009CP1	199	1061	154	1246	38	529
								02cc11022orf2	010CP1	232	2145	159	1678	39	530
04ce11617orf16	009CP1	207	1069	161	1253	40	531
								049e11617orf26	009CP1	211	1073	162	1254	41	532
14ce21516orf1	001CP7	1306	1757	163	416	42	533
								04ce11617orf4	009CP1	214	1076	164	1256	43	534
04ee70114orf10	001CP7	220	1082	169	1261	44	535
								hp4e14535orf3	009CP1	1414	1865	181	434	45	536
04ge11713orf9	009CP1	246	1108	185	1277	46	537
								04gp11213orf11	009CP1	247	1109	186	1278	47	538
04gp11213orf4	009CP1	248	1110	187	1279	48	539
								04gp11213orf22	009CP1	249	1111	138	1280	49	540
04gP11803orf13	009CP1	254	1116	191	1283	50	541
								05ae20220orf119	009CP1	263	1125	195	1287	51	542
05ae20220orf56	009CP1	270	i132	197	1289	52	543
								05ae20220orf58	009CP1	271	1133	198	1290	53	544
05ae20220orf95	010CP1	280	1142	201	1293	54	545
								02ep30607orf32	009CP1	297	2210	204	1723	55	546
0Sap21216orr4	009CP1	290	1152	206	1298	56	547
								05ce10420orf1	009CP1	291	1153	207	1299	57	548
05cp11911orf35	009CP1	297	1159	209	1301	58	549
								05cp20518orf39	009CP1	305	1167	212	1304	59	550
05ee10411orf5	009CP1	308	1170	213	1305	60	551
								05ep11717orf2	009Cp1	314	1176	219	1311	61	552
05gP11901orf19	009CP1	324	1186	225	1317	62	553
								05gp20111orf12	009CP1	326	1188	227	1319	63	554
05gP20111orf4	009CP1	328	1190	229	1321	64	555
								05gp20111orf6	009CP1	329	1191	230	1322	65	556
06ce10808orf2	009CP1	343	1205	243	1335	66	557
								06cp11118orf7	009CP1	352	1214	251	1343	67	558
06cp30603orf15	009CP1	364	1226	262	1354	68	559
								06cp30603orf16	009CP1	365	1227	263	1355	69	560
06ep10306orf5	009CP1	373	1235	266	1358	70	561
								06ep11108orf17	009CP1	378	1240	270	1362	71	562
06ge10115orf17	009CP1	386	1248	277	1369	72	563
								06ge10115orf19	009CP1	387	1249	278	1370	73	564
06ge10115orf4	009CP1	388	1250	279	1371	74	565
								07ap11111orf13	009CP1	408	270	297	1380	75	566

07ee11519orf1	009CP1	422	1284	304	1396	76	567
								07gp11807orf17	009CP1	448	1310	323	1415	77	568
07gp31516orf9	009CP1	453	1315	326	1418	78	569
								09ap20802orf14	010CP1	465	1327	337	1429	79	570
05ap10914orf3	010CP1	569	2482	345	1864	80	571
								05ce10613orf1	010CP1	586	2499	349	1868	81	572
05ce10613orf2	009CP1	587	2500	350	1869	82	573
								09ge70821orf2	009CP1	491	1353	354	1446	83	574
11ap11902orf3	009CP1	497	1359	357	1449	84	575
								11cp12006orf13	009CP1	521	1383	381	1473	85	576
11ee10423orf1	009CP1	530	1392	390	1482	86	577
								11ee10423orf4	009CP1	531	1393	391	1483	87	578
11ge10309orf12	009CP1	534	1396	394	1486	88	579
								11ge10309orf7	009CP1	551	1413	395	1487	89	580
12ap10324orf6	009CP1	565	1427	398	1490	90	581
								12ge10305orf5	009CP1	573	1435	403	1495	91	582
13ae10511orf3	009CP1	587	1449	410	1502	92	583
								13ae10712orf15	009CP1	592	1454	413	1505	93	584
13ap11517orf15	009CP1	599	1461	418	1510	94	585
								13ee10216orf7	009CP1	610	1472	422	1514	95	586
13ep12003orf21	009CP1	625	1487	435	1527	96	587
								14ae21813orf2	009CP1	630	1492	438	1530	97	588
14ce10720orf12	001CP6	631	1493	439	1531	98	589
								02ep30607orf19	009CP1	1065	1516	440	1372	99	590
14ce10720orf3	009CP1	632	1494	440	1532	100	591
								14cp10705orf4	009CP1	645	1507	447	1539	101	592
14ee10308orf1	009CP1	649	1511	451	1543	102	593
								14ee10308orf4	010CP1	651	1513	452	1544	103	594
06cp11722orf11	009CP1	739	2652	454	1973	104	595
								14ce11217orf2	009CP1	655	1517	456	1548	105	596
14ce11217orf3	010CP1	656	1518	457	1549	106	597
								06cp11722orf5	009CP1	745	2658	460	1979	107	598
14ge10705orf14	009CP1	660	1522	461	1553	108	599
								14gp11820orf1	001CP6	663	1525	464	1556	109	600
04ge11713orf35	010CP1	1098	1549	466	1398	110	601
								06cp20302orf3	010CP1	751	2664	466	1985	111	602
06cp20302orf5	010CP1	752	2665	467	1986	112	603
								06cp20302orf6	010CP1	753	2666	468	1987	113	604
06cp20302orf7	010CP1	754	2667	469	1988	114	605
								06ee10207orf1	009CP1	763	2676	471	1990	115	606
29ge10307orf3	010CP1	679	1541	475	1567	116	607
								06ee11611orf1	009CP1	770	2683	475	1994	117	608
29ge10307orf4	010CP1	680	1542	476	1568	118	609
								06ep10306orf10	010CP1	773	2686	477	1996	119	610
06ep10306orf11	009CP1	774	2687	478	1997	120	611
								hp1e10523orf3	009CP1	687	1549	481	1573	121	612
hp1p13852orf4	009CP1	700	1562	494	1586	122	613
								hp1p13852orf6	009CP1	701	1563	495	1587	123	614
hp1p13852orf7	009CP1	702	1564	496	1588	124	615
								hp1p13947orf11	009CP1	708	1570	502	1594	125	616
hp1p14013orf17	009CP1	715	1577	508	1600	126	617
								hp2e10229orf2	009CP1	716	1578	509	1601	127	618

hp2e10229orf4	009CP1	717	1579	510	1602	128	619
								hp2e10911orf24	010CP1	722	1584	515	1607	129	620
06gp10108orf2	001CP6	816	2729	516	2035	130	621
								07ap11015orf2	009CP1	1167	1618	520	1452	131	622
hp2e11858orf6	001CP6	730	1592	520	1612	132	623
								07ap11015orf4	009CP1	1168	1619	521	1453	133	624
hp2p10272orf1	009CP1	733	1595	522	1614	134	625
								hp2p10625orf5	009CP1	742	1604	525	1617	135	626
hp2p10625orf6	009CP1	743	1605	526	1618	136	627
								hp3e10349orf27	009CP1	751	1613	530	1622	137	628
hp3e11024orf34	009CP1	763	1625	539	1631	138	629
								hp3e11024orf49	009CP1	767	1629	543	1635	139	630
hp3e11024orf5	009CP1	768	1630	544	1636	140	631
								hp3e11075orf3	010CP1	773	1635	546	1638	141	632
07ap80601orf2	010CP1	863	2776	548	2067	142	633
								07ce10203orf11	010CP1	871	2784	554	2073	143	634
07ce10203orf17	009CP1	873	2786	556	2075	144	635
								hp3p11086orf1	010CP1	796	1658	561	1653	145	636
07ce11206orf1	009CP1	884	2797	567	2086	146	637
								hp4p13446orf13	009CP1	808	1670	571	1663	147	638
11ce10917orf10	009CP1	498	1360	572	1504	148	639
								hp1p13446orf3	009CP1	809	1671	572	1664	149	640
hp5e15211orf23	010CP1	827	1689	581	1673	150	641
								07cp11213orf1	009CP1	905	2818	584	2103	151	642
hp5p15612orf2	009CP1	848	1710	594	1686	152	643
								hp5p15641orf23	001CP6	851	1713	596	1688	153	644
12ap10324orf5	010CP1	1265	1716	598	1530	154	645
								07ep30818orf4	009CP1	932	2845	600	2119	155	646
01ce11618orf11	009CP1	52	1965	607	1699	156	647
								01ce11618orf22	009CP1	61	1974	608	1700	157	648
01ce11618orf27	009CP1	62	1975	609	1701	158	649
								01ce11618orf7	009CP1	67	1980	610	1702	159	650
01ce11618orf9	009CP1	68	1981	611	1703	160	651
								01cp11710orf16	009CP1	84	1997	612	1704	161	652
01cp11710orf18	009CP1	86	1999	613	1705	162	653
								01cp11710orf5	009CP1	90	2003	615	1707	163	654
01cp11710orf6	009CP1	91	2004	616	1708	164	655
								01cp11710orf9	009CP1	93	2006	617	1709	165	656
01ge10203orf14	009CP1	125	2038	618	1710	166	657
								01ge10203orf6	009CP1	128	2041	619	1711	167	658
01ge10203orf7	009CP1	129	2042	620	1712	168	659
								03ge10505orf2	009CP1	376	2289	644	1736	169	660
04ce11617orf10	001CP6	404	2317	645	1737	170	661
								14gp12015orf13	001CP6	1330	1781	648	1580	171	662
14gp12015orf16	009CP1	1332	1783	650	1582	172	663
								04ge11210orf1	009CP1	449	2362	651	1743	173	664
04ge11713orf10	009CP1	455	2368	653	1745	174	665
								04ge11713orf28	009CP1	462	2375	655	1747	175	666
04ge11713orf36	010CP1	464	2377	656	1748	176	667
								09ap11406orf2	009CP1	1014	2927	657	2176	177	668
04gp11213orf5	001CP6	487	2400	661	1753	178	669
								29ge10111orf1	009CP1	1353	1804	669	1601	179	670

05ae20220orf37	001CP6	548	2461	675	1767	180	671
								hp2e10911orf25	009CP1	1377	1828	686	1618	181	672
06ap10209orf1	009CP1	697	2610	690	1782	182	673
								06ap10209orf4	009CP1	699	2612	691	1783	183	674
06ee10709orf2	009CP1	767	2680	695	1787	184	675
								06ep10306orf1	009CP1	772	2685	696	1788	185	676
07cp10312orf5	009CP1	898	2811	703	1795	186	677
								07cp21714orf1	009CP1	908	2821	706	1798	187	678
07cp21714orf3	009CP1	910	2823	708	1800	188	679
								09ap20802orf13	009CP1	1025	2938	713	1805	189	680
09ap20802orf21	010CP1	1031	2944	714	1806	190	681
								11ce10908orf1	001CP6	1100	3013	716	2235	191	682
hp4p11352orf9	009CP1	1419	1870	718	1650	192	683
								11ge10309orf24	009CP1	1155	3068	725	1817	193	684
11ge10309orf28	009CP1	1157	3070	727	1819	194	685
								11ge10309orf39	009CP1	1164	3077	731	1823	195	686
11ge10309orf4	009CP1	1165	3078	732	1824	196	687
								11ge10309orf5	010CP1	1166	3079	733	1825	197	688
11cp12002orf3	009CP1	1129	3042	745	2264	198	689
								13ae10610orf1	010CP1	1245	3158	747	1839	199	690
11ee10423orf2	009CP1	1137	3050	753	2272	200	691
								14cp10119orf1	010CP1	1349	3262	758	1850	201	692
11ge10308orf1	009CP1	1145	3058	761	2280	202	693
								14ee10308orf7	009CP	1375	3288	762	1854	203	694
14ge10705orf3	009CP1	1411	3324	763	1855	204	695
								hp1e10506orf5	009CP1	1495	3408	766	1858	205	696
hp3p10807orf4	009CP1	1746	3659	775	1867	206	697
								hp3p10807orf7	009CP1	1749	3662	776	1868	207	698
hp4e12063orf1	010CP1	1754	3667	777	1869	208	699
								12ap10324orf8	009CP1	1200	3113	778	2297	209	700
hp4p11352orf5	010CP1	1783	3696	782	1874	210	701
								12ge10610orf2	010CP1	1217	3130	784	2303	211	702
13ee12016orf7	010CP1	1312	3225	844	2363	212	703
								14ee10419orf5	010CP1	1384	3297	898	2417	213	704
14ec11217orf4	010CP1	1390	3303	904	2423	214	705
								14ee21118orf1	010CP1	1391	3304	905	2424	215	706
14ee21118orf2	010CP1	1392	3305	906	2425	216	707
								14ep11115orf3	010CP1	1397	3310	911	2430	217	708
14ep11905orf73	010CP1	1400	3313	914	2433	218	709
								14ep11905orf9	010CP1	1408	3321	922	2441	219	710
29ap10306orf3	010CP1	1462	3375	957	2476	220	711
								29ap11902orf1	010CP1	1463	3376	958	2477	221	712
29ep20112orf2	010CP1	1469	3382	964	2483	222	713
								29ge10111orf3	010CP1	1471	3384	966	2485	223	714
hp1e10554orf1	010CP1	1500	3413	982	2501	224	715
								hp1p10543orf4	010CP1	1506	3419	988	2507	225	716
hp1p13947orf10	010CP1	1552	3465	1025	2544	226	717
								hp2e10911orf35	010CP1	1592	3505	1047	2566	227	718
hp3e10057orf3	010CP1	1617	3530	1062	2581	228	719
								hp3e10128orf1	010CP1	1619	3532	1064	2583	229	720
hp3c10302orf17	010CP1	1627	3540	1072	2591	230	721
								hp3e10302orf26	010CP1	1633	3546	1078	2597	231	722

hp3e11122orf3	010CP1	1693	3606	1127	2646	232	723
								hp3p10156orf2	010CP1	1715	3628	1141	2660	233	724
hp3p10156orf3	010CP1	1716	3629	1142	2661	234	725
								hp3p10156orf7	010CP1	1718	3631	1144	2663	235	726
hp3p10304orf2	010CP1	1724	3637	1148	2667	236	727
								hp3p10807orf6	010CP1	1748	3661	1160	2679	237	728
hp3p11086orf2	010CP1	1753	3666	1164	2683	238	729
								hp4e14535orf7	010CP1	1776	3689	1178	2697	239	730
hp4e14535orf18	010CP1	1777	3690	1179	2698	240	731
								hp4p11393orf1	010CP1	1785	3698	1182	2701	241	732
hp4p11393orf2	010CP1	1786	3699	1183	2702	242	733
								hp4p11393orf6	010CP1	1790	3703	1187	2706	243	734
hp4p12005orf2	010CP1	1792	3705	1189	2708	244	735
								hp4p13446orf5	010CP1	1806	3719	1203	2722	245	736
hp5p15580orf1	010CP1	1889	3802	1258	2777	246	737
								hp5p15653orf1	010CP1	1898	3811	1264	2783	247	738
hp5p15653orf2	010CP1	1899	3812	1265	2784	248	739
								04ap20904orf3	010CP1	205	1067	1281	2800	249	740
06gp11920orf11	010CP1	398	1260	1288	2807	250	741
								12ge20305orf26	010CP1	581	1443	1301	2820	251	742
13ee10216orf57	009CP1	609	1471	1303	2822	252	743
								04cP11202_24256567_c3_117	009CP1			783	1715	253	744
01ae11010_40688_c2_38	009CP1			790	1882	254	745
								01ae12001_242187 81_f2_18	009CP1			791	1883	255	746
01ge11619_23711062_c3_14	009CP1			795	1887	256	747
								01gP11016_4103403_c2_13	009CP1			799	1891	257	748
02ae11612_104212_f1_1	009CP1			800	1892	258	749
								02ae11612_22477267_f2_27	009CP1			802	1894	259	750
02ae11612_23598175_f1_2	009CP1			803	1895	260	751
								02ae11612_33203250_c1_51	009CP1			804	1896	261	752
02ge10116_36367936_c1_19	009CP1			807	1899	262	753
								02ge11622_875260_f3_36	009CP1			809	1901	263	754
02gp20706_1203402_c3_58	009CP1			810	1902	264	755
								02gp20706_15781452_c2_51	009CP1			813	1905	265	756
02gp20706_23632775_f3_32	009CP1			815	1907	266	757
								02gp20706_23866562_c2_53	009CP1			816	1908	267	758
02gp20706_4892558_f3_19	009CP1			821	1913	268	759
								02gp20814_24415958_f3_9	009CP1			824	1916	269	760
04cp11202_24261588_f2_23	010CP1			827	1919	270	761
								07ap11015_23938312_f3_2	009CP1			831	1763	271	762
05ae30220_21619067_f3_56	009CP1			835	1927	272	763
								07ap11213_35401528_c1_21	009CP1			835	1767	273	764
05ae30220_24882812_c3_1 03	009CP1			837	1929	274	765
								05ae30220_25953163_c3_98	009CP1			839	1931	275	766
05ee10816_14649077_f3_1 8	009CP1			841	1933	276	767
								05ee10816_4103408_f2_11	009CP1			843	1935	277	768
05ee10816_4687651_c1_22	009CP1			844	1936	278	769
								06ap11119_16594193_f1_9	009CP1			845	1937	279	770
06ap20306_23437632_f3_9	009CP1			851	1943	280	771
								06cp30603_23452_c3_80	009CP1			854	1946	281	772
06cp30603_23476568_c1_44	009CP1			855	1947	282	773
								06cP30603_4689068_c3_79	009CP1			857	1949	283	774

07ap11111_234693_c3_14	009CP1			860	1952	284	775
								07ap20216_7227202_f3_10	009CP1			865	1957	285	776
07ep11916_5273452_c3_31	009CP1			866	1958	286	777
								09cp11003_19532625_c3_17	009CP1			869	1961	287	778
09cp20502_24001388_c1_31	009CP1			871	1963	288	779
								12gp31106_3024126_f2_25	009CP1			876	1968	289	780
13ae10712_14100018_f2_12	009CP1			879	1971	290	781
								13ae10712_29569208_c2_27	009CP1			880	1972	291	782
14ap10815_20585777_c1_13	009CP1			884	1976	292	783
								29ge30321_34157812_f3_10	009CP1			886	1978	293	784
hp1p14013_11726503_c2_20	009CP1			888	1980	294	785
								hp2p10272_23697200_f3_22	009C P1			891	1983	295	786
hp2p10272_26829136_f1_1	009CP1			894	1986	296	787
								hp5e15211_819455_c2_24	009CP1			897	1989	297	788
hp5p15212_34064750_f2_9	009CP1			901	1993	298	789
								hp5p15641_21698387_c2_20	009CP1			904	1996	299	790
hp6e10967_23476502_f2_6	009C P1			908	2000	300	791
								hp6e10967_24882750_f2_7	009CP1			909	2001	301	792
hp6e12267_4876718_f2_23	009CP 1			912	2004	302	793
								hp6e20339_1190660_c2_46	009CP1			913	2005	303	794
hp6e20339_21492187_c1_40	009CP1			914	2006	304	795
								hp6e20339_34024187_c1_37	009CP1			916	2008	305	796
01ge10203_35281542_c3_16	009CP1			930	2022	306	797
								01ge10203_860166_f3_9	009CP1			931	2023	307	798
01ge11619_13788141_c2_11	009CP1			932	2024	308	799
								01ge11619_24415880_c2_12	009CP1			934	2026	309	800
01ge11619_24417813_c1_8	009CP1			935	2027	310	801
								02gp20706_16g03513_f1_1	009CP1			946	2038	311	802
02gp20706_20365905_f2_8	009CP1			947	2039	312	803
								02gp20814_398481 8_f1_1	009CP1			949	2041	313	804
04cp11202_16603425_c2_72	009CP1			955	2047	314	805
								04cp11202_19797128_f1_5	009CP1			956	2048	315	806
04cP11202_23553177_c1_75	009CP1			957	2049	316	807
								04cp11202_23553177_c3_109	009CP1			958	2050	317	808
04ge10816_22086531_f2_10	009CP1			963	2055	318	809
								04ge10816_33726080_c2_29	009CP1			964	2056	319	810
05ae30220_14350428_f1_9	009CP1			969	2061	320	811
								05ae30220_9882767_f2_34	009CP1			978	2070	321	812
05cp21223_4725443_f3_14	009CP1			981	2073	322	813
								05ee10816_259703_f2_7	009C P1			982	2074	323	814
06ap11119_24426508_f3_26	009CP1			984	2076	324	815
								06ee10709_21675012_f1_2	009CP1			993	2085	325	816
07ce11019_22051291_f1_1	009CP1			1004	2096	326	817
								07ep11916_5913592_f3_18	009CP1			1006	2098	327	818
09cp11003_5945252_f2_4	009CP1			1013	2105	328	819
								09ze10333_22460750_f2_6	009CP1			1014	2106	329	820
12ge10321_4821082_f3_14	009CP1			1028	2120	330	821
								14ap10221_13689381_c3_4	009CP1			1035	2127	331	822
29ep10720_24220926_f2_8	009CP1			1046	2138	332	823
								29ep10720_24432762_c3_39	009CP1			1047	2139	333	824
29ge30321_12913562_f1_1	009CP1			1050	2142	334	825
								29ge30321_35253_f2_6	009CP1			1051	2143	335	826

29ge30321_21673965_f2_7	009CP1			1052	2144	336	827
								29ge30321_24336712_f1_5	009CP1			1053	2145	337	828
hp2p10272_22692325_f3_21	009CP1			1059	2151	338	829
								hp2p10272_24406280_c1_26	009CP1			1060	2152	339	830
hp3p10807_29343768_f1_1	009CP1			1061	2153	340	831
								hp3p10807_29352212_f2_5	009CP1			1062	2154	341	832
hp6e20339_24317062_c3_57	009CP1			1078	2170	342	833
								hp6p10233_12273302_f1_1	009CP1			1087	2179	343	834
02ep20506_24611325_f2_6	010CP1			1341	2860	344	835
								07ap11213_35156577_c1_24	010CP1			1410	2929	345	836
07ap80601_976413_f3_9	010CP1			1414	2933	346	837
								hp3p10807_189075_f2_4	010CP1			1464	2983	347	838
02ge11622_21695936_c1_54	010CP1			1493	3012	348	839
								12ge10321_24308513_f3_20	010CP1			1504	3023	349	840
14ce21516_85786_f1_1	010CP1			1508	3027	350	841
								hp6e12267_14650278_f3_29	010CP1			1517	3036	351	842
06cp30603_23476568_c2_133.aa						352	843
								06ce20610_1367157_f1_8.aa						353	844
06ep30223_4698838_f2_55						354	845
								12ap10324_4805318_f2_3						355	846
14ee41924_2458267_c2_93						356	847
								06ep1191724803153_c3_24						357	848
01ce11104_36125337_c1_8						358	849
								01ce21104_33203250_c3_87						359	850
02ae31010_34616666_f2_27						360	851
								02ae31 010 35270000_f3_33						361	852
02ae31010_36132785_f2_29						362	853
								02ge10116_15781452_c1_87						363	854
02ge10116_16803513_f2_34						364	855
								02ge10116_16803513_f2_34						365	856
02ge10116_36367936_c1_92						366	857
								03ae10804_23485968_c3_47						367	858
05ce10910_25598277_f3_3						368	859
								06ae11016_30579712_f2_21						369	860
06ce20610_29298537_c2_32						370	861
								06ce20610_3913967_c3_36						371	862
06ce20610_4331338_f3_18						372	863
								06cp11118_212827_c1_17						373	864
06cp11217_19720300_f3_11						374	865
								06cp11217_4881263_f2_9						375	866
06cp11217_4897077_f1_6						376	867
								06cp30603_21492187_f2_41						377	868
06cp30603_34024187_f1_20						378	869
								06cp30603_34024187_f1_20						379	870
06ep10615_14649077_f3_52						380	871
								06eP10615_9842_f3_46						381	872
06ep11202_26353438_c1_22						382	873
								06ep30223_23557202_c2_130						383	874
06ep30223_34409437_f3_94						384	875
								06ep30223 4698838_f2_55						385	876
06ep30223_4876077_c3_149						386	877
								06ep30223_5109443_c1_109						387	878

06ep30223_5271902_c1_106						388	879
								06gp10409_3398427_f2_12						389	880
06gp71906_24261588_c2_174						390	881
								06gp71906_970325_c3_190						391	882
07ae10923_24426508_f1_1						392	883
								07ae10923_24426508_f1_1						393	884
09ce10413_414011_f1_3						394	885
								09ce10413_5865665_f1_4						395	886
09ce52017_29324062_c1_21						396	887
								09cp10224_1062966_c3_61						397	888
09cp10224_1412715_c3_56						398	889
								09cp10224_429510_c2_46.aa						399	890
09cp10224_4484718_c1_38						400	891
								09cp21607_7224187_c2_12						401	892
09cp61003_14562637_c2_93						402	893
								09cp61003_19532625_c1_78						403	894
09cp61003_24063587_c1_74						404	895
								09cp61003_24335762_c3_111						405	896
09cp61003_5945252_f1_5						406	897
								11ae80818_11188791_c3_60						407	898
11ae80818_783127_c3_63						408	899
								11ae80818_7952_c1_49						409	900
11ap20714_4960432_c3_97						410	901
								11ap20714_5271967_c1_60						411	902
11ap20714_7227202_f3_43.aa						412	903
								11ap20714_7227202_f3_43.aa						413	904
14ce31519_15635927_f3_15						414	905
								14ee41924_23527267_c3_107						415	906
14ee41924_23834800_f2_32						416	907
								hp1p13939_25397327_f3_22						417	908
hp2e10911_24855312_c1_69						418	909
								hp2e10911_3349_c1_63						419	910
hp4e13394_35957200_f1_21						420	911
								hp4e13394_5964452_c2_97						421	912
hp4e53394_22864682_c2_86.aa						422	913
								hp5e15044_4554652_f3_3						423	914
hp5p15575_29300311_c1_29						424	915
								hp5p15575_33445317_f2_20.aa						425	916
hp5p15575_6140713_f2_18						426	917
								hp5p15641_12195281_c1_24						427	918
hp5p15641_24304527_c3_35						428	919
								hp5p15641_25635452_c3_34						429	920
hp5p15870_14350428_f1_1						430	921
								hp6p10590_23440913_c2_31						431	922
hp6p10606_19546933_c3_31						432	923
								hp6p10903_4398263_f3_6.aa						433	924
hp6p10903_4398263_f3_6.aa						434	925
								hp6p10904_2214676_c1_14						435	926
hp6p10904_23704412_f2_5						436	927
								01cp20708_36134808_f2_11						437	928
02ae31010_12504512_f3_28.aa						438	929
								02ae31010_16833312_f2_19						439	930

02ae31010_2117087_f3_34						440	931
								02ae31010_30208317_f1_14						441	932
02ae31010_36132785_f2_29						442	933
								02ae31010_5085162_c1_47						443	934
02cp10615_26573462_c1_45						444	935
								03ae10804_12609533_c1_6						445	936
03ae10804_21698400_c2_32						446	937
								04ep41903_26757937_f3_16						447	938
04ep41903_26757937_f3_16						448	939
								04ep41903_4101593_f2_10.aa						449	940
05ep10815_26570332_c2_99						450	941
								05ep10815_4195292_c1_84						451	942
05ep10815_4719175_c1_83						452	943
								06cp30603_679218_f2_34						453	944
06ep10615_961562_f2_41						454	945
								06ep11202_133293_c1_19						455	946
06ep11202_26353438_c1_22						456	947
								06ep11202-4884677_c1_17						457	948
06ep11202_792962_c2_26.aa						458	949
								06ep11917_24803153_c3_24						459	950
06ep30223_16512_c3_160						460	951
								06ep30223_23476067_c1_119						461	952
06gp71906_15115637_f2_59						462	953
								06gp71906_25478192_c1_131						463	954
06gp71906_25504187_f3_112						464	955
								09cp61003_492187_c2_80.aa						465	956
11ae80818_19632781_c3_57						466	957
								11ae80818_7290627_c2_51						467	958
11ap20714_34023312_f3_46						468	959
								11ee11408_4977193_c1_41.aa						469	960
11ge10308_5256_f2_1						470	961
								12ap10324_13178562_f3_6						471	962
14ce61516_13073577_f2_12						472	963
								14ee41924_16282067_c1_72						473	964
hp2e10911_4882027_c2_87						474	965
								hp3e11188_47327_f2_5						475	966
hp3e11183_5082842_f3_12						476	967
								hp4e13394_3368767_c1_80						477	968
hp5p15212_692S132_c3_34						478	969
								hp5p15641_30273312_c2_28						479	970
hp5p1564L5211687_c2_29						480	971
								hp6p10590_30521093_f2_14						481	972
hp6p10904_7089062_c1_16						482	973
								hp6p12129_16603417_f3_14						483	974
hp6p12244_3948467_c1_52						484	975
								hp6p22217_23470967_f1_4						485	976
hp7e10192_4412568_f2_5						486	977
								hp7p10287_24611325_c2_24						487	978
hp7p10290_25548812_f3_14						488	979
								hp7p10290_25585941_6_12						489	980
hp7p10290_35156558_f3_15						490	981
								hp7p10290_4351718_f1_6						491	982

11ae11922_12586675_f2_1						983	1037
								02ge10116_23866562_c3_146						984	1038
07ee11402_2458267_c3_108						985	1039
								07ee50709_1021 3593_f3_77						986	1040
06ep10615_14649077_f2_30						987	1041
								09cp10713_23452_c3_195						988	1042
11ap20714_7227202_f3_40						989	1043
								01ce61016_23609580_c3_139						990	1044
06gp71906_3024126_c1_128						991	1045
								06ge20501_1410001 8_c1_34						992	1046
09cp10713_34024187_f1_31						993	1047
								hp4p62853_5914693_c3_52						994	1048
13ae10610_859692_c2_32						995	1049
								13ae10610_35912_f2_3						996	1050
06ap11119_24426508_f3_27						997	1051
								14gp11423_26803801_f3_7						998	1052
06ap10609_12586675_f2_19						999	1053
								07ee50709_4818967_f2_43						1000	1054
02ap1117_23495187_c3_81						1001	1055
								09cp10713_34024187_f1_31						1002	1056
07ee50709_35156577_f3_80						1003	1057
								05ae30220_976413_c3_204						1004	1058
hp3e11188_47327_f2_9						1005	1059
								12ap10324_4805318_f2_6						1006	1060
hp1e80523_23485968_c2_49						1007	1061
								hp7c10192_25598277_c2_15						1008	1062
hP4e53394_26209843_c3_98						1009	1063
								06ep10615_9842_f1_5						1010	1064
06ep30223_34409437_f2_64						1011	1065
								06gp10409_3398427_f2_12						1012	1066
09ce10413_5865665_f1_4						1013	1067
								09cp10224_1062966_c1_44						1014	1068
01ce61016_12931513_c2_106						1015	1069
								01ce61016_23609580_c3_139						1016	1070
14cp11908_25593768_c3_97						1017	1071
								14cp11908_783127_c1_72						1018	1072
07ee11402_10759567_c2_86						1019	1073
								07ee50709_4818967_f2_43						1020	1074
hp4e13394_5088562_f3_54						1021	1075
								hp4e13394_15828963_c2_90						1022	1076
hp4e53394_19720300_c3_98						1023	1077
								07ce10312_4554652_f3_2						1024	1078
05ae30220_14350428_f3_91						1025	1079
								hp8e10080_19546933_c2_88						1026	1080
01ce10320_30273587_f3_38						1027	1081
								07ee50709_26438968_f2_36						1028	1082
05ep10815_4719175_c1_115						1029	1083
								06ep30223_23476067_c1_115						1030	1084
hp7e10590_26172564_c1_68						1031	1085
								05ae30220_4977193_c3_198						1032	1086
hp7e10557_21698387_f1_1						1033	1087
								07ee11402_19565702_c2_88						1034	1088

07ee50709_960952_f2_47						1035	1089
								hp6p12244_3948467_c3_88						1036	1090
hp7e10590_13073577_c3_107						1293	1296
								01ce61016_492187_c3_120						1294	1297
06ep10615_961562_f1_15						1295	1298

Examples

I cloning and sequencing of helicobacter pylori

Extraction of H.pylori chromosomal DNA the basic DNA manipulation procedure outlined in Schleif R.F. and Wensink P.C. "molecular biology methods of use", page 98, Springer-Verlag, NY,1981, was followed with minor modifications. Briefly, cells were harvested by centrifugation, resuspended in TE (10mM Tris,1mM EDTA, pH7.6), and GES lysis buffer (5.1M thiocyanogen guanidine, 0.1M EDTA, pH8.0, 0.5% N-dodecylsarcosine) was added. The suspension is cooled and ammonium acetate (C) is added ) To a final concentration of 2.0M. The DNA was extracted with chloroform, followed by phenol-chloroform and then chloroform. DNA was precipitated with isopropanol, washed twice with 70% ethanol, dried, and resuspended in TE.

Helicobacter pylori whole genome DNA was extracted and then nebulized into 2000 bp medium-sized fragments (Bodenteich et al, automated DNA sequencing and analysis (edited by J.C. Venter), Academic Press, 1994). After nebulization, theDNA was concentrated and separated on a standard 1% agarose gel. Several fractions corresponding to the size of approximately 900-1300bp, 1300-1700bp, 1700-2200bp and 2200-2700 bp were excised from the gel and purified using the GeneClean program (Bio101, Inc.).

The purified DNA fragment was then end-blunted with T4DNA polymerase. The ligated DNA was then ligated with a 100-fold 1000-fold excess of a single Bst XI-linker. These linkers were complementary to the bstxi cut pMP x vector, while their overhangs were not self-complementary. Therefore, the linker does not form a concatemer, and the cleaved vector is not easily ligated to itself. The adaptor-bearing insert was separated from the non-integrated adaptor on a 1% agarose gel and purified using GeneClean. The ligated inserts were then ligated into each of the 20 pMPX vectors to construct a series of "shotgun" subclone libraries. The vector contains an out-of-frame LacZ gene at the cloning site, which becomes in-frame after linker duplex cloning and can thus be excluded by its blue color.

All subsequent steps are based on the multiplex DNA sequencing procedure outlined by Church G.M. and Kieffer-Higgins S. science 240, 185-188, 1988. Only major modifications indicate that, briefly, each of the 20 vectors were transformed into E.coli DH5 α competent cells (Gibco/BRL, DH5 α transformation method). the library was evaluated by plating onto antibiotic plates containing ampicillin, methicillin and IPTG/Xgal. the plates were incubated overnight at 37 ℃ and successful transformants were used for clone plating and mixed into a multiplex mixture. clones were picked and mixed into 40mL growth medium cultures grown overnight at 37. the DNA was purified using the Qiagen Midi-prep kit and Tip-100 columns (Qiagen, Inc.) in this method, 96 preparations of 15 DNA-containing wells per mixture were made to obtain a 5-10 fold redundant well plate sequence of 250-300 base length.

These purified DNA samples were then sequenced by multiplex DNA sequencing according to the chemical degradation method (Church G.M. and Kieffer-Higgins S., science 240, pp.185-188, 1988) or by the Sequithrem (epicenter technologies) dideoxy sequencing method. Will be provided withSequencing reactions were electrophoresed and transferred from 40cm gels (Richich P. and Church G.M. (methods in enzymology) 218, page 187-222, 1993) onto nylon membranes by direct transfer electrophoresis or by electroblotting (Church et al, supra). Each piece was run with 24 samples. 45 successful membranes were prepared by chemical sequencing and 8 blocks were prepared by dideoxy sequencing. The DNA was covalently bound to the membrane by exposure to UV light and hybridized with labeled oligonucleotides complementary to the vector tag sequences (Church, supra), the membrane was washed to remove non-specifically bound probes, and exposed on X-ray film to visualize individual ladders. Following autoradiography, the hybridized probe was removed at 65 ℃ and the hybridization process repeated with another marker sequence until the membrane was hybridized 38 times with probe for the chemically sequenced membrane and 10 times for the dideoxy sequenced membrane. Thus, each piece of film produces a large number of films, each containing new sequencing information. When any new blot is run, the internal standard sequence added to each mixture is initially probed. Digital images of the films were prepared using a laser scanning densitometer (Molecular Dynamics, Sunnyvale, CA). The digital images are reproduced on computer workstations (VaxStation 4000's) by a program REPLICA^TM(Chruch et al, "automated DNA sequencing and analysis" (edited by J.C. Venter), Academic Press, 1994). Image processing includes lane straightening, contrast adjustment to eliminate intensity differences, and repeated gaussian reduction to improve resolution. Then in REPLICA^TMThe sequence is automatically picked and displayed to allow flexible correction before the project data is stored. Correction is accomplished by rapid visual scanning of the film image and then modifying the bases called by mouse-clicking on the displayed band, REPLICA for a typical sequence obtained by chemical sequencing^TMThe error rate of the base call software is 2-5%, most errors occur at the end of the sequence read. Many sequence errors can be detected and corrected because multiple sequencing covering the same portion of genomic DNA can provide sufficient sequence redundancy for editing. Each sequence was automatically assigned a number corresponding to (microtiter plate and probe signals) and the number of bands (pair)Corresponding to the arrangement of microtiter plates). This number can be used as a parameter to identify the sequence, and thus any original specific sequence can generally be determined without having to resort to a specific database.

Routine alignment program for H.pylori FALCON^TM(Church, Church et al, "automated DNA sequencing and analysis" (edited by J.C. Venter), Academic Press, 1994). This procedure has proven to be fast and reliable for most sequences. The aligned contigs are shown using a modified version of GelAssemble, a program developed by Genetic Computer Group (GCG) (Devereux et al, nucleic acids research, Vol. 12, pp. 387-95, 1984) and compatible with REPLICA^TMAnd (4) compatibility. This provides a complete editor for multiple sequencing gel images to be rapidly reproduced from REPLICA^TMCalled out and displayed to rapidly scan contigs and correct gel blots for differences in different sequence reads during alignment.

II identification, cloning and expression of helicobacter pylori nucleic acids

The expression and purification of the H.pylori polypeptide of the invention can be carried out essentially as outlined below.

To facilitate cloning, expression and purification of membrane and secreted proteins from H.pylori, we chose a gene expression system for cloning and expression of recombinant proteins in E.coli, such as the PET system (Novagen). Furthermore, a DNA sequence encoding a polypeptide tag-histidine tag is fused to the 3' end of the DNA sequence of interest to facilitate purification of the recombinant protein. The 3 'end was chosen for fusion in order to avoid any changes to the 5' end signal sequence. An exception to this is ppiB, a gene that was cloned for use as a control in expression studies. The sequence of helicobacter pylori ppiB contains a DNA sequence encoding a His tag fused to the 5' end of the full-length gene, because the protein product of this gene does not contain a signal sequence and is expressed as a cytoplasmic protein.

PCR amplification and cloning of nucleic acids of ORF containing membrane and secretory peptides from helicobacter pylori

A nucleic acid selected for cloning from the H.pylori J99 strain (for example, a nucleic acid listed in the sequence listing) was prepared, and cloning was performed by amplification using Polymerase Chain Reaction (PCR). Synthetic oligonucleotide primers specific for the 5 'and 3' ends of the reading frames (ORFs) were designed and purchased from GibcoBRL Life Technologies (Gaithersburg, Md., USA). All forward primers (specific for the 5 'end of the sequence) were designed to contain a NcoI cloning site at the 5' extreme end. These primers were designed to allow protein translation to start with methionine followed by a valine and the remaining coding sequence of the native H.pylori DNA sequence. All reverse primers (specific for the 3 'end of any H.pylori ORF) contained an EcoRI site at the 5' extreme end, so that each H.pylori sequence was cloned into the reading frame of pET28 b. The pET28b vector provided a sequence (at the C-terminus) encoding 20 additional carboxy-terminal amino acids containing 6 histidine residues, which contained a His tag. An exception to this is the vector constructed for the ppiB gene, as described above. The synthetic oligonucleotide primer specific for the 5 'end of the ppiB gene encodes a BamHI site at its 5' extreme end, while the primer specific for the 3 'end of the ppiB gene encodes an XhoI site at its 5' extreme end.

Genomic DNA prepared from the H.pylori J99 strain was used as a source of template DNA for PCR amplification reactions (latest methods in molecular biology, edited by John Wiley and Sons, Inc., F.Ausubel et al, 1994). To amplify the DNA sequence containing the H.pylori ORF, genomic DNA (50 ng) was loaded into a reaction vial containing: 2mM 1 micromolar synthetic oligonucleotide primers (forward and reverse primers) complementary to the specific H.pylori ORF and its wings, 0.2mM of each deoxynucleotide triphosphate, i.e. dATP, dGTP, dCTP, dTTP and 2.5 units of thermostable DNA polymerase (Amplitaq, Roche Molecular Systems, Inc., Branchburg, NJ, USA), in a total reaction volume of 100 microliters.

After completion of the thermocycling reaction, each amplified DNA sample was washed and purified using the qiaquick spin PCR purification kit (Qiagen, Gaithersburg, MD, USA). All amplified DNA samples were digested with restriction enzymes such as NcoI and EcoRI (New England Biolabs, Beverly, MA, USA) (latest methods in molecular biology, edited by John Wiley and Sons, Inc., F. Ausubel et al, 1994). The DNA samples were then electrophoresed on a 1.0% NuSeive (FMC BioProducts, Rockland, ME, USA) agarose gel. The DNA was treated with ethidium bromide and visualized by excitation with long-wave UV light. DNA contained in the band separated from the gel was purified with a Bio101 GeneClean kit (Bio101 Vista, Calif., USA).

Cloning of helicobacter pylori nucleicacid into one expression vector

The pET-28b vector is prepared for cloning by digestion with restriction enzymes such as Nco I and EcoRI (latest methods in molecular biology, edited by John Wiley and Sons, Inc., F.Ausubel et al, 1994). In cloning ppiB, pET-28a vector encoding a His tag fused to the 5' end of the inserted gene was used, and the cloning site for cloning ppiB gene was prepared by digestion with BamHI and XhoI restriction enzymes. After digestion, the DNA insert was cloned into a pET-28b expression vector that had been previously digested (latest methods in molecular biology, John Wiley and Sons, Inc., edited by F.Ausubel et al, 1994), with the exception of the ppiB amplification insert, which was cloned into the pET-28a expression vector. The ligation product was then used to transform E.coli strain BL21 as described below (latest methods in molecular biology, edited by John Wiley and Sons, Inc., F.Ausubel et al, 1994).

Transformation of competent bacteria with recombinant plasmids

Competent cells of the E.coli strain BL21 or of the E.coli strain DL21(DE3) were transformed with the pET expression plasmid carrying the cloned helicobacter pylori sequence according to standard methods (latest methods in molecular biology, John Wiley and Sons, Inc., edited by F.Ausubel et al, 1994). Briefly, 1 microliter of ligation reaction was mixed with 50 microliters of electrocompetent cells, then subjected to high voltage, after which the sample was placed in 0.45ml of SOC medium (0.5% yeast extract, 2.0% tryptone, 10 mM) 、2.5mM 、10mM 、10mM And 20mM glucose) at 37 ℃ for 1 hour. The samples were then plated on LB agarplates containing 25 mg/ml kanamycin sulfate for overnight growth. The transformed clones of BL21 were then picked and analyzed to evaluate the inserts of the clones as described below.

Identification of recombinant expression vectors carrying helicobacter pylori nucleic acids

The single BL21 clone transformed with recombinant pET-28b H.pylori ORFs was analyzed by PCR amplification of the cloned insert using the same forward and reverse primers specific for each H.pylori sequence used in the original PCR amplification cloning reaction. Successful amplification confirmed the integration of the H.pylori sequence in the expression vector (latest methods in molecular biology, edited by John Wiley and Sons, Inc., F.Ausubel et al, 1994).

Isolation and preparation of nucleic acids from transformants

Individual clones carrying the recombinant pET-28b vector containing the ORFs of helicobacter pylori of the appropriate clones were picked and incubated overnight in 5ml LB broth supplemented with 25. mu.g/ml kanamycin sulfate. The following day plasmid DNA was isolated and purified using Qiagen plasmid purification procedures (Qiagen Inc, Chatsworth, Calif., USA).

Expression of recombinant helicobacter pylori sequences in E.coli

pET can be propagated in any E.coli K12 strain, e.g., HMS174, HB101, JM09, DH5, etc., for cloning or plasmid preparation expression hosts include E.coli strains containing a chromosomal copy of the T7 RNA polymerase gene, these hosts are lysogens of bacteriophage DE3, DE3 is a lambda derivative carrying the Lac I gene, the LacUV5 promoter and the T7 RNA polymerase gene, T7 RNA polymerase is induced by the addition of isopropyl- β -thiogalactoside (IPTG), T7 RNA polymerase can transcribe any plasmid carrying its target gene, e.g., pET-28b, using strains including BL21(DE3) (Studier, F.W., Rosenberg, A.H., Dunn, J.J., and Dubendoff, J.W (1990) methods of enzymology 185, pp.60-89).

For the expression of the recombinant helicobacter pylori sequence, competent BL21(DE3) bacteria (supplied by Novagen as part of a pET expression system kit) were transformed with 50 ng of the plasmid isolated as above as described. The LacZ gene (B-galactosidase) was expressed in the pET system as described for the recombinant construction of H.pylori. The transformed cells were cultured in SOC medium for 1 hour, and then the culture was plated on a plate containing 25. mu.g/ml kanamycin sulfate. The following day, bacterial colonies were mixed and cultured in LB medium containing kanamycin sulfate (25. mu.g/ml) to O.D. units with an optical density of 0.5 to 1.0 at 600 nM, at which time 1 millimole of IPTG was added to the culture for 3 hours to induce expression of the H.pylori recombinant DNA construct.

After induction of gene expression with IPTG, the bacteria were collected by centrifugation at 3500 Xg for 15 minutes at 4 ℃ using a Sorvall RC-3B centrifuge. The pellet was resuspended in 50. mu.l of ice-cold 10mM 、pH8.0、0.1M And 0.1mM EDTA (STE buffer). The cells were then centrifuged at 2000 Xg for 20 minutes at 4 ℃. The wet weight of the precipitate was weighed and frozen at-80 ℃ for protein purification.

III purification of recombinant proteins from E.coli

Analytical method

The concentration of the purified protein was measured spectrophotometrically using the absorption coefficient calculated from the amino acids contained (Perkins, S.J.,1986, J. Eur. biochem., 157, 169-180). Protein concentrations can also be measured using the method of Bradford,M.M (1976) analytical biochemistry, Vol.72, pp.248-.

SDS-polyacrylamide gels (12% or 4.0 to 25% acrylamide gradient gels) were purchased from BioRad (Hercules, Calif., USA) and stained with Coomassie Brilliant blue. Molecular weight standards include rabbit skeletal muscle myosin (200kDa), E.coli galactosidase (116kDa), rabbit muscle phosphorylase B (97.4kDa), bovine serum albumin (66.2kDa), ovalbumin (45kDa), carbonic anhydrase (31kDa), soybean trypsin inhibitor (21.5kDa), ovalbumin lysozyme (14.4kDa) and bovine aprotinin (6.5 kDa).

1. Purification of soluble proteins

All steps were carried out at 4 ℃. Frozen cells were thawed and resuspended in 5 volumes of lysis buffer (20mM Tris, pH7.9, 0.5M) 5mM imidazole and containing 10% glycerol, 0.1% mercaptoethanol, 200g/ml lysozyme, 1mM phenylmethylsulfonyl fluoride (PMSF), and 10ug/ml leupeptin, aprotinin, pepstatin, L-1-chloro-3- [ 4-methylsulfanyl]-7-amino-2-heptanone (TCLK), L-1-chloro-3- [ 4-methylsulfamide]4-benzene-2-butanone (TPCK) and soybean trypsin inhibitor) and passed several times through a small volume microfluidizer (model M-110S, microfluidics International Corporation, Newton, MA). The resulting homogenate was made to contain 0.1% Brij 35. And centrifuged at 10,000 Xg for 1 hour to give a clear supernatant (crude extract).

Passing the crude extract through a 0.8cm super filter (Gelman Sciences, FRG), and directly passing the crude extract over a filter Nitrolotriacetate-agarose (NTA) column, having a bed volume of 5ml (Hochuli, E., Dbeli, H. and Schacher, A. (1987) J.chromatographie.411, page 179. 184), equilibrated beforehand with lysis buffer containing 10% glycerol, 0.1% Brj35 and 1mM PMSF, washed with 250ml (50 bed volumes) of lysis buffer containing 10% glycerol, 0.1% Brj35 and subsequently eluted with a gradient of lysis buffer containing 10% glycerol, 0.05Brij35, 1mM PMSF and 20, 100, 200 or 500mM imidazole. By OD₂₈₀The absorbance at nm was monitored for each fraction, and the peak fractions were analyzed by SDS-PAGE.

2. Purification of insoluble proteins from endosomes

The following procedure was performed at 4 ℃ and the cell pellet was resuspended in lysis buffer containing 10% glycerol, 200g/ml lysozyme, 5mM EDTA, 1mM phenylmethylsulfonyl fluoride (PMSF), 0.1% mercaptoethanol. After passing the cell suspension through a cell disruptor, the resulting homogenate containing 0.2 deoxycholic acid was stirred for 10 minutes, centrifuged at 20,000 Xg for 30 minutes, and the pellet was washed with lysis buffer containing 10% glycerol, 10mM EDTA, 1% TritonX-199, 1mM PMSF and 0.1% mercaptoethanol followed by several washes with lysis buffer containing 1M urea, 1mM PMSF and 0.1% mercaptoethanol, producing a white pellet consisting essentially of inclusion bodies, free of unbroken cells and membrane material.

Dialysis and concentration of protein samples

Slow removal of Urea from protein samples was performed by subjecting the samples to Tris buffer salt (TBS; 10mM Tris, pH8.0,150 mM) containing 0.5% deoxycholic acid ) Dialysis was performed and urea was decreased as follows: 6M, 4M, 3M, 2M, 1M, 0.5M, and finally TBS without urea. Each dialysis step was performed at room temperature for a minimum of 4 hours.

After dialysis, the sample was concentrated by pressure filtration using an Amicon stir chamber. Protein concentrates were measured by the methods of Perkins (1986, J. Eur. biochem., 157, 169-.

VI antigenicity evaluation of helicobacter pylori outer membrane localization antigen

Purification of the H.pylori outer membrane was carried out essentially as outlined below.

Helicobacter pylori strains J99(ATCC #55679) and Ah224 were contained in chocolate blood agar containing 5% (v/v) horse serum at 10% at 37% For 48 hours. Bacteria were suspended in 20mM Tris, pH7.5 to harvest the bacteria. The cells were collected by centrifugation at 12,000 Xg for 20 minutes at 4 ℃ and washed 3 times with 20mM Tris, pH 7.5. Cells were resuspended in 20mM Tris, pH7.5, and sonicated on ice for 8 hours (60 watts, 30 seconds total 8 times with an interval of 60 seconds). In cell suspensionDNase (0.1mg) and RNase (0.5mg) were added to the solution. And the mixture was incubated at room temperature for 30 minutes. The cell suspension was centrifuged at 12,000 Xg for 20 minutes at 4 ℃. The supernatant was retained and centrifuged once more. The total membranes were collected from the supernatant by centrifugation at 40,000 Xg for 30 minutes at 4 ℃. The precipitate was washed twice in 20mM Tris, pH 7.5. The protein content was analyzed by the Bradford protein assay with Bovine Serum Albumin (BSA) as a control. The suspension was then adjusted to 1mg protein/ml. Dissolution of the membrane was achieved by adding N-dodecyl-sarcosine to the suspension in a proportion of 6mg N-dodecyl-sarcosine per mg protein. The suspension was incubated in the presence of dodecyl-sarcosine for 30 minutes at room temperature. The outer membrane was collected by centrifugation at 40,000 Xg for 30 minutes at 4 ℃. The pellet was washed 3 times with MilliQ grade water, aliquoted and stored at-20 ℃ until needed.

Identification of helicobacter pylori outer membrane antigen

Proteins were separated on sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) according to the method described in Laemmli U.K. (1970) Nature 227, 680-685. Samples were prepared by suspending in standard processing buffer and heating at 100 ℃ for 10 min. Approximately 1-5mg per well was loaded on a 8X 10cm small gel (0.75 mm). The isolated proteins were then transferred to PVDF as described below.

Electroblotting of the isolated proteins onto PVDF membrane was performed in a Bio-Rad Mini-Trans-Blot chamber. Using PVDF membrane Immobil-pSQ, electroblots were performed using CAPS transfer buffer (10mM3- [ cyclohexylamine]-1-propanesulfonic acid, 10% methanol) and 50V for 60 min. The membranes were stained with 0.2% Fuchun Red S and destained with Milli grade Q water.

The antigen in the preparation was then identified by western immunoblotting. After electroblotting, the non-specific binding sites of the PVDF membrane were used at 10mM -0.9％ 5% skim milk at pH 7.5. Membranes were incubated with normal mouse serum at 10mM -0.9％ 0.5% Tween 20-0.5% BSA, appropriate dilution in pH7.5, incubated at 37 ℃ for 2 hours and incubated with 10mM -0.9％ 0.5% Tween 20pH7.5(TTBS) 3 washes. The alkaline phosphatase-conjugated goat anti-mouse Ig was then added to 10mM -0.9％ 0.5% Tween 20-0.5% BSA, pH7.5, incubated at room temperature for 1 hour. After incubation, the membrane was washed 3 times with TTBS. The reaction band was developed with 5-bromo-4-chloro-3-indolylphosphate (Bio-Rad) as an alkaline phosphatase substrate and nitroblue tetrazolium (Bio-Rad) as a color developer.

For amino acid microsequencing, the immunologically active band was excised from a fresh unreacted Immobilon membrane and microsequenced on the Worcester Foundation microsequencing apparatus. The excised membrane was then subjected to western immunoblotting as described above to confirm that the appropriate band had been excised.

Analysis of H.pylori protein as vaccine candidate

To investigate the immunomodulatory effects of H.pylori, we used a mouse/H.pylori model. This model mimics human H.pylori infection in several ways. The concept of therapeutic oral immunotherapy was examined with emphasis on the effect of oral immunization in H.pylori infected animals.

Animal(s) production

Female SPF BALB/c mice were purchased from Bomholt Breeding Center (Denmark) and were housed in common large cages, and were given food and water ad libitum. These animals were 4-6 weeks old at arrival.

Infection with viral infection

After a minimum of one week of acclimation, the animals were infected with a type 2 (VacA negative) helicobacter pylori strain 224, originally isolated from an ulcerative patient. We have already demonstrated that this strain is able to colonize the stomach of mice well. The bacteria are supplemented with 10% of fetal cattleSerum in Brookfield Broth, slightly aerobic at 37 ℃ (10% 、5％ ) And grown overnight. Omeprazole (400umol/kg) was orally administered to these animals and helicobacter pylori (about 10) in the broth was orally inoculated 3-5 hours later⁸cfu/animal), the positive rate of infection was detected in some animals 2-3 weeks after inoculation.

Antigens

Recombinant H.pylori antigens are selected on the basis of their association with the outwardly exposed H.pylori cell membrane, the antigens being selected from the group consisting of (1) outer membrane proteins, (2) periplasmic/secretory proteins, (3) outer surface proteins and (4) inner membrane proteins all recombinant proteins have been constructed for purification reasons to contain a 6-histidine tag-control proteins other than H.pylori (β -galactosidase from E.coli; LazZ) are constructed in the same way.

All antigens were in soluble form, i.e. either dissolved in HEPES buffer or in buffer containing 0.5% deoxycholic acid (DOC).

The antigens are listed in Table 8 below

TABLE 8

Helicobacter pylori protein

Outer Membrane proteins

Protein 1

Protein 2

Protein 3

Protein 4

Protein 5

Periplasmic/secretory proteins

Protein 6

Other envelope proteins

Protein 7

Protein 8

Flagellin-related proteins

Protein 9

Control proteins

β -galactosidase (LazZ)

Immunization

Each group of 10 animals was immunized 4 times within 34 days (days 1, 15, 25 and 35). The purified antigen in solution or suspension was administered at a dose of 100 ug/mouse. As an adjuvant, 10 ug/mouse of Cholera Toxin (CT) was also administered to the animals per immunization. Omeprazole (400umol/kg) is administered orally to animals 3-5 hours prior to immunization as a method of protecting antigens from acid degradation. Infected control animals received either HEPES buffer + CT or DOC buffer + CT. Animals were sacrificed 2-4 weeks after the last immunization. A general summary of the study is shown in table 9 below.

TABLE 9

Mice were infected with H.pylori strain Ah224 on day 30

Mouse strain is administrated with substrate n =10 dose/mouse date 1. control, PBS Balb/c 0.3ml 0, 14, 24, 342. cholera toxin, 10ug Balb/c 0.3ml 0, 14, 24, 343. protein 1,100ug + CT 10ug Balb/c 0.3ml 0, 14, 24, 344. protein 5,100ug + CT 10ug Balb/c 0.3ml 0, 14, 24, 345. protein 10,100ug + CT 10ug Balb/c 0.3ml 0, 14, 24, 346. protein 9,100ug + CT 10ug Balb/c 0.3ml 0, 14, 24, 347. protein 2,100ug + CT 10ug Balb/c 0.3ml 0, 14, 24, 347. protein 6,100ug + CT 10ug Balb/c 0.3ml 0, 14, 24, 349. protein 0.3 ug + CT 0.3ml, 14 ug, 24. 3410, protein 7,100ug + CT 10ug Balb/c 0.3ml 0, 14, 24, 3411, protein 8,100ug + CT 10ug Balb/c 0.3ml 0, 14, 24, 3412, protein 3,100ug + CT 10ug Balb/c 0.3ml 0, 14, 24, 34

Analysis of infection

Mucosal infection: for mice Killing by cervical vertebra disruption, opening abdominal cavity, taking out stomach, cutting along the greater curvature of stomach to stimulate appetite, and washing in saline. Scraping 25mm from the stomach cavity and stomach body with surgical knife²And (3) mucosa. Scraped mucosa was suspended in Brookfield broth and plated on Blood Skirrow selection plates. The plates were incubated under microaerobic conditions for 3-5 days and the number of colonies was counted. Helicobacter pylori was confirmed by urease and catalase tests and direct microscopic examination or gram staining.

The urease test was performed essentially as follows, reagent-urea agar based concentrates were purchased from DIFCO Laboratories Detroit, MI (Catalog # 0284-61-3). Urea agar based concentrates were diluted 1: 10 with water and 1ml of the diluted concentrate was mixed with 100-200 ul of actively growing H.pylori cells, a color change to magenta indicating that the cells were urease positive.

Catalase assays were performed essentially as follows, reagent-N, N, N-N-tetramethyl-p-phenylenediamine, each available from Sigma, St Louis, MO (Catalog # T3134). A solution of the reagents (1% w/v in water) was prepared. Helicobacter pylori cells were scraped onto Whatman filter paper and covered with a 1% solution, and the color turned dark green indicating that the cells were positive for hydrogen peroxide.

Serum antibody: in all mice, sera were prepared from blood collected by cardiac puncture. Serum antibodies were identified using conventional ELISA techniques, in which helicobacter pylori-specific antigens were plated.

Mucosal antibody: specific sites of 4cm of the stomach and duodenum were gently scraped in 50% mice to detect the presence of antibody in the mucosa. Antibody titers were determined using the same conventional ELISA in serum antibodies.

Statistical analysis: the Wilcoxon-Mann-Whitneg signed rank-sum test was used to determine the significant effect of the antigen on H.pylori colonization, p<0.05 was considered significant, with emphasis on determining changes in luminal colonization as the gastric lumen is the primary colonization site for H.pylori.

Results

Serum antibody: all test antigens administered with CT produced detectable specific titers in serum. The highest responses were seen for proteins 3,4, 9,1 and 7 (see fig. 1).

Antibody in mucosa: specific antibodies against all antigens can be seen in the scraped mucosa, and the strongest response has been seen to date for protein 6, followed by 1,3 and 9 (see fig. 2). Effect of therapeutic immunization:

all control animals (BALB/c mice) were well colonised by H.pylori (strain AH224) in the gastric cavity and corpus. Of all the antigens tested, 3 proteins (proteins 4, 7 and 1) were able to reduce or eliminate the H.pylori infection well and significantly. The degree of gastric cavity colonization was lower after immunization with proteins 8, 9 and 3 compared to controls. The effect of proteins 5,2 and 6 was indistinguishable from the control. The control protein LacZ, i.e.the non-H.pylori protein, has no clearance effect and is in fact able to colonize H.pylori higher than the HEPES + CT control. All data for proteins soluble in HEPES and DOC are shown in figures 3 and 4, respectively, and the data are shown as geometric means with n =8-10, Wilcoxon-Mann-Whitney signed rank sum test = p<0.05; x/10= number of mice showing helicobacter pylori clearance among the total number of all tested mice.

The data presented show that all H.pylori-associated proteins included in this study, when used as an oral source of immunity together with the oral adjuvant CT, are able to produce stimulation of the immune response, as measured by specific serum and mucosal antibodies. Most proteins cause a reduction in H.pylori colonization in this animal model, which under certain conditions may lead to complete clearance. It should be noted that the reason for the reduction or elimination is heterologous protection rather than homologous protection (polypeptides based on the H.pylori J99 strain sequence, used against different vaccinating bacteria (AH244) in therapeutic immunization studies). This indicates that the vaccine has the potential to protect against a variety of H.pylori strains.

The highest colonization in the gastric lumen was seen for animals treated with the non-helicobacter protein LacZ, indicating that the effect seen with the H.pylori antigen is specific.

The data are pooled and strongly support the use of these H.pylori proteins in a pharmaceutical preparation for the treatment and/or prevention of H.pylori infection in humans.

VI sequence difference analysis of genes in helicobacter pylori strains

The 4 genes were cloned and sequenced from several H.pylori strains to compare the DNA and deduced amino acid sequences. This information was used to determine sequence differences between H.pylori strain J99 and other H.pylori strains isolated from patients.

Preparation of chromosomal DNA

Cultures of helicobacter pylori strains (as shown in Table 12) were grown to OD in BLBB (1% tryptone, 1% Peptamin, 0.1% glucose, 0.2% yeast extract, 0.5% sodium chloride, 5% fetal bovine serum)₆₀₀Is 0.2. Cells were harvested in a Sorvall RC-3B centrifuge at 4 ℃ using 3,500 Xg centrifugation for 15 minutes and the pellet resuspended in 0.95ml of 10mM 0.1mM EDTA (TE), lysozyme was added to a final concentration of 1mg/ml, and SDS to 1%, RNAse + T1 to 0.5mg/ml and 5 units/ml, respectively, were also added, and the mixture was incubated at 37 ℃ for 1 hour. Proteinase K was then added to a final concentration of 0.4mg/ml and the samples were incubated at 55 ℃ for more than 1 hour. Adding into the sample To a concentration of 0.65M, carefully mixed and added 0.15ml of a solution in 0.7M 10% CTAB (final concentration of 1% CTAB/70 mM) ) Followed by incubation at 65 ℃ for 20 minutes. At this time, the sample was extracted with chloroform/isoamyl alcohol, phenol, and chloroform/isoamyl alcohol. The DNA was precipitated with ethanol (1.5 vol) or isopropanol (0.6 vol) at-70 ℃ for 10 min, washed with 70% ethanol and resuspended in TE.

PCR amplification and cloning

Genomic DNA prepared from 12 helicobacter pylori strains was used as a source of template DNA for PCR amplification reactions (latest methods in molecular biology, edited by John Wiley and Sons, Inc., F.Ausubel et al, 1994). To amplify the DNA sequence containing the ORF of helicobacter pylori, genomic DNA (10 ng) was loaded with a DNA sequence containingIn a divided reaction tube: 2mM 1 micromolar synthetic oligonucleotide primers complementary to the specific H.pylori ORF and to either flank thereof (forward and reverse primers, see Table 10), 0.2mM of each deoxynucleotide triphosphate, i.e., dATP, dGTP, dCTP, dTTP, 0.5 units of thermostable DNA polymerase (Amplitaq, Roche Molecular Systems, Inc., Branchburg, NJ, USA) the reaction was performed in a total volume of 20 microliters and in two replicates.

Watch 10

Oligonucleotide primer for PCR amplification of helicobacter pylori DNA sequence

Outer Membrane proteins	Forward primer 5 'to 3'	Reverse primer 5 'to 3'
			Protein 11 (against strain) AH4,AH15,AH61, 5294,5640, AH18, and AH244)	5’-TTAACCATGGTGAAAAGC GATA-3’(SEQ ID NO:1091)	5’-TAGAATTCGCCTCTAAAA CTTTAG-3’(SEQ ID NO:1092)
protein 11 (against strain) AH5,51 55,7958, AH24, and J99)	5’-TTAACCATGGTGAAAAGC GATA-3’(SEQ ID NO:1093)	5’-TAGAATTCGCATAACGAT CAATC-3’(SEQ ID NO:1094)
			Protein 12	5’-ATATCCATGGTGAGTTTG ATGA-3’(SEQ ID NO:1095)	5’-ATGAATTCAATTTTTTATT TTGCCA-3’(SEQ ID NO:1096)
Protein 13	5’-AATTCCATGGCTATCCAA ATCCG-3’(SEQ ID NO:1097)	5’-ATGAATTCGCCAAAATC GTAGTATT-3’(SEQ ID NO:1098)
			Protein 14	5’-GATACCATGGAATTTATGA AAAAG-3’(SEQ ID NO:1099)	5’-TGAATTCGAAAAAGTGT AGTTATAC-3’(SEQ ID NO:1100)

The following thermal cycling conditions were used to obtain amplified DNA products of each ORF using a Perkin Elmer Cetus/GeneAmp PCR System9600 thermal cycler.

The sequences of protein 12 and protein 14;

heat denaturation at 94 ℃ for 2 min;

2 cycles of 94 ℃ for 15 seconds, 30 ℃ for 15 seconds, 72 ℃ for 1.5 minutes;

at 94 deg.C, 15 seconds, 55 deg.C, 15 seconds, 72 deg.C, 1.5 minutes, 23 cycles;

the reaction was completed at 72 ℃ after 6 minutes.

The sequence of protein 11 of strains AH5, 5155, 7958, AH24 and J99;

heat denaturation at 94 ℃ for 2 min;

2 cycles of 94 ℃ for 15 seconds, 30 ℃ for 15 seconds, 72 ℃ for 1.5 minutes;

at 94 deg.C, 15 seconds, 55 deg.C, 15 seconds, 72 deg.C, 1.5 minutes, 25 cycles;

the reaction was completed at 72 ℃ after 6 minutes.

The sequences of protein 11 and protein 13 of strains AH4, AH15, AH61, 5294,5640, AH18 and Hp 244;

heat denaturation at 94 ℃ for 2 min;

2 cycles of 94 ℃,15 seconds, 30 ℃, 20 seconds, 72 ℃,2 minutes;

25 cycles of 94 ℃,15 seconds, 55 ℃, 20 seconds, 72 ℃ and 2 minutes;

the reaction was completed after 8 minutes at 72 ℃.

After the thermocycling reaction was complete, each pair of samples was mixed. And used for direct cloning into a pCR cloning vector according to the method described below.

Cloning the DNA sequence of helicobacter pylori into pCR TA cloning vector

All amplified inserts were cloned into pCR2.1 vector as described in the original TA cloning kit (Invirogen, san Diego, Calif.) and the ligation products were then used to transform the TOP10F 'strain of E.coli (INVaF' in the case of H.pylori sequence 350) as described below.

Transformation of competent bacteria with recombinant plasmids

Competent bacteria E.coli strains TOP10F 'or E.coli INVaF' were transformed with recombinant pCR expression plasmids harboring the cloned H.pylori sequence according to standard methods (latest methods in molecular biology, John Wiley and Sons, Inc., edited by F.Ausubel et al, 1994). Briefly, 2 microliters of 0.5 micromolar BME was added to each vial containing 50ul of competent cells, followed by mixing 2 microliters of ligation reaction with the competent cells, incubation on ice for 30 minutes, then "heat shocking" the cells and ligations at 42 ℃ for 30 seconds, followed by another 2 minutes on ice, and then adding the sample to 0.45ml SOC medium (0.5% yeast extract, 2.0% tryptone, 10 mM) 、2.5mM 、10mM 、10mM And 20mM glucose) was incubated at 37 ℃ for 1 hour with shaking. The samples were then plated on LB agar plates containing 25. mu.g/ml kanamycin or 100. mu.g/ml ampicillin overnight. Transformed colonies of either TOP10F 'or INVaF' were then picked and analyzed as described below to evaluate the cloned inserts.

Identification of recombinant PCR plasmids carrying helicobacter pylori sequences

Individual TOP10F 'or INVaF' clones transformed with recombinant pCR H.pylori ORFs were analyzed by PCR amplification of the cloned inserts using the same forward and reverse primers specific for each H.pylori sequence used in the original PCR amplification cloning reaction. Successful amplification confirmed the integration of the H.pylori sequence in the cloning vector (latest methods in molecular biology, edited by John Wiley and Sons, Inc., F.Ausubel et al, 1994).

Individual clones of recombinant pCR vector carrying appropriately cloned H.pylori ORF were picked for sequence analysis. Sequence analysis was performed on an ABI sequencer using standard methods (PerkinElmer) using vector specific primers (found in pCRII or pCR2.1, Invitrogen, San Diego, Calif.) and sequencing primers specific for the ORF as shown in Table 11 below.

TABLE 11

Oligonucleotide primer for helicobacter pylori DNA sequencing

Outer Membrane proteins	Forward primer 5 'to 3'	Reverse primer 5 'to 3'
			Protein 11	5’-CCCTTCATTTTAGAAATCG-3’ (SEQ ID NO:1101) 5’-ATTTCAACCAATTCAATGCG-3’ (SEQ ID NO:1102) 5’-GCCCCTTTTGATTTGAAGCT-3’ (SEQ ID NO:1103) 5’-TCGCTCCAAGATACCAAG AAGT-3’(SEQ ID NO:1104) 5’-CTTGAATTAGGGGCAAAG ATCG-3’(SEQ ID NO:1105) 5’-ATGCGTTTTTACCCAAAGA AGT-3’(SEQ ID NO:1106) 5’-ATAACGCCACTTCCTTATTG GT-3’(SEQ ID NO:1107)	5’-CTTTGGGTAAAAACGCATC-3’ (SEQ ID NO:1108) 5’-CGATCTTTGATCCTAATTCA-3’ (SEQ ID NO:1109) 5’-ATCAAGTTGCCTATGCTGA-3’ (SEQ ID NO:1110)
Protein 12	5’-TTGAACACTTTTGATTATG CGG-3’(SEQ ID NO:1111) 5’-GGATTATGCGATTGTTTTA CAAG-3’(SEQ ID NO:1112)	5’-GTCTTTAGCAAAAATGGCGTC- 3’(SEQ ID NO:1113) 5’-AATGAGCGTAAGAGAGCCTTC- 3’(SEQ ID NO:1114)
			Protein 13	5’-CTTATGGGGGTATTGTCA-3’ (SEQ ID NO:1115) 5’-AGCATGTGGGTATCCAGC-3’ (SEQ ID NO:1116)	5’-AGGTTGTTGCCTAAAGACT-3’ (SEQIDNO:1117) 5’-CTGCCTCCACCTTTGATC-3’ (SEQ ID NO:1118)
Protein 14	5’-ACCAATATCAATTGGCACT-3’ (SEQ ID NO:1119) 5’-ACTTGGAAAAGCTCTGCA-3’ (SEQ ID NO:1120)	5’-CTTGCTTGTCATATCTAGC-3’ (SEQ ID NO:1121) 5’-GTTGAAGTGTTGGTGCTA-3’ (SEQ ID NO:1122)
				5’-CAAGCAAGTGGTTTGGTTTT AG-3’(SEQ ID NO:1123) 5’-TGGAAAGAGCAAATCATTG AAG-3’(SEQ ID NO:1124)	5’-GCCCATAATCAAAAAGCCCAT- 3’(SEQ ID NO:1125) 5’-CTAAAACCAAACCACTTGC TTGTC-3’(SEQ ID NO:1126)
Carrier primer	5’-GTAAAACGACGGCCAG-3’ (SEQ ID NO:1127)	5’-CAGGAAACAGCTATGAC-3’ (SEQ ID NO:1128)

Results

To establish the error rate of PCR in these experiments, we prepared 5 individual clones of protein 11 from 5 individual PCR reaction mixtures of H.pylori strain J99, sequenced the full length 897 nucleotide for these 5 clones, and accumulated a total DNA sequence of 4485 bases. The DNA sequences of the 5 clones were compared with the DNA sequence of protein 11 previously obtained by a different method, namely random shotgun cloning and sequencing. The error rate of PCR in the experiments described herein was determined to be 2 base changes in 4485 bases, which is consistent with an estimated 0.04% or less.

DNA sequence analysis was performed on4 different open reading frames, which were identified as genes and amplified from 12 different H.pylori strains by PCR. Of the four open reading frames selected in this study, three deduced amino acid sequences showed statistically significant BLAST homology to specific proteins present in other bacterial species. These ORFs include: protein 11, which is homologous to the Val a&B gene of an ABC transporter encoded in f.novicida; protein 12, which is homologous to lipoprotein e (p4) present in the outer membrane of Haemophilus influenzae; protein 13, which is homologous to fecA, an outer membrane receptor for ferric (iii) dicitrate trafficking by e. Protein 14 was identified as an unknown open reading frame because it showed very low homology to sequences in public databases.

To assess the extent of conservation or difference in ORF between individual strains of H.pylori, changes in DNA sequence and deduced protein sequence were compared with those found in H.pylori 99 strain (see Table 12 below). The results are expressed in the same percentage as the H.pylori J99 strain obtained by random shotgun clone sequencing. To control any variation in the sequence of the J99 strain, the 4 open reading frames were each recloned and sequenced once from the J99 bacterial strain and the sequence information obtained was compared to that collected with inserts from random shotgun clones of the J99 strain and the data demonstrated variations in the DNA sequence ranging from 0.12% difference (protein 14, J99 strain) to approximately 7% change (protein 11, strain AH 5). The deduced protein sequence showed no variation (protein 14, strains AH18 and AH24) or up to 7.66% amino acid changes (protein 11, strain AH 5).

TABLE 12

Multi-strain sequence analysis of H.pylori vaccine candidates

J99 protein number #: 1111121213131414

Sequencing region 248a.a 746nt. 232 a.a.696 696nt. 182 a.a.548 548nt. 273 a.a.819 nt.

Length of (d):

detection of strains

AA Nuc. AA Nuc. AA Nuc. AA Nuc.

Identity

J99100.00％ 100.00％100.00％ 100.00％100.00％ 100.00％ 99.63％ 99.88％

AH244 95.16％ 95.04％ n.d. n.d. 99.09％ 96.71％ 98.90％ 96.45％

AH4 95.97％ 95.98％ 97.84％ 95.83％ n.d. n.d 97.80％ 95.73％

AH5 92.34％ 93.03％ 98.28％ 96.12％ 98.91％ 96.90％ 98.53％ 95.73％

AH15 95.16％ 94.91％ 97 41％ 95.98％ 99.82％ 97 99％ 99.63％ 96.09％

AH61 n.d n.d. 97.84％ 95.98％ 99.27％ 97.44％ n.d. n.d.

5155 n.d. n.d. n.d. n.d. 99.45％ 97.08％ 98.53％ 95.60％

5294 94.35％ 94.37％ 98.28％ 95.40％ 99.64％ 97.26％ 97.07％ 95.48％

7958 94.35％ 94.10％ 97.84％ 95.40％ n.d. n.d. 99.63％ 96.46％

5640 95.16％ 94.37％ 97.41％ 95.69％ 99.09％ 97.63％ 98.53％ 95.48％

AH18 n.d. n.d. 98 71％ 95.69％ 99.64％ 97.44％ 100.00％ 95.97％

AH24 94.75％ 95.04％ 97.84％ 95.40％ 99.27％ 96.71％ 100.00％ 96.46％

n.d. = not determined

VII knockout experiment method for determining basic helicobacter pylori gene as potential therapeutic target

Therapeutic targets are selected from genes whose protein products may play a key role in the basic cellular pathway. Examples of such cellular pathways are cell membrane synthesis, DNA synthesis, transcription, regulation, translation and colonization/virulence.

The techniques for deletion of portions of the H.pylori gene/ORF and insertional mutagenesis of the kanamycin resistance cassette were modified from previously reported methods (Labigne-Roussel et al, 1988, journal of bacteriology 170, 1704-

Identification and cloning of the Gene sequence of helicobacter pylori

The gene or ORF (open reading frame) selected as the target for knockout was identified from the H.pylori genomic sequence and used to design primers capable of specifically amplifying the gene/ORF. All synthetic oligonucleotide primers (Table 13) were designed with the help of OLIGO program (national biosciences, Inc. Plymouth, MN 55447, USA) and purchased from Gibco/BRL Life Technologies (Gaithersburg, Md. USA). Specific primers (F1 and R1) were chosen to localize to either flank of most or all ORFs, depending on their size. If the ORF is less than 800 to 1000 base pairs, the flanking primers are selected outside the open reading frame.

TABLE 13 oligonucleotide sequences for group/ORF knock-outs

		Cloning primer		Primers for generating deletions		Targeting primer
								Gene Name (R)	Login number	F1	R1	F2	R2	F3	R3
rnh	P23329	TTGCCCCATCGTA TTGATAGA (SEQ ID NO:1129)	AGAGCGTATTTCA CCCGAAAG (SEQ ID NO:1130)	TCTTGCATCTTAAT CCACTCC (SEQ ID NO:1131)	CGGGTCAAAACGA CCACTTAA (SEQ ID NO:1132)	AATCCGTTTCGCT AATTTAGT (SEQ ID NO:1133)	AACACTTCAATTT CCTCTATA (SEQ ID NO:1134)
								ppiB	P29820	TGGTATAAGGATT TGAATGGA (SEQ ID NO:1135)	TTGACTAAACACA TGCGAGAA (SEQ ID NO:1136)	ATAGAGAGCGTTG TGTTTAGC (SEQ ID NO:1137)	CCTTTATTGGTTTT GATCGTG (SEQ ID NO:1138)	ATGTCCGTTGTCT GTATGGAA (SEQ ID NO:1139)	TAGGGTGTCTAG GGATTTGAT (SEQ ID NO:1140)
tsf	P34828	GCGTTTGGCTTCTT CGTTGTC (SEQ ID NO:1141)	GAAATGGAAAATA GCGGTCAA (SEQ ID NO:1142)	GCAAATCCCCAGC CACTTCC (SEQ ID NO:1143)	GTGGCTAAAAATG AGGGCTT (SEQ ID NO:1144)	GTTAGGAAATTAG AAATCATTG (SEQ ID NO:1145)	GCTAAAACTTCAT CGCTCAAT (SEQ ID NO:1146)
								MurD	P14900	GTTGGGCAGAAAA TAAGGTGA (SEQ ID NO:1147)	CAAACAAACCTGA CAAGAAAC (SEQ ID NO:1148)	CATTGATGCCTAA AACTTCG (SEQ ID NO:1149)	CGTGGTGGTTTTC CCGTTAG (SEQ ID NO:1150)	GGGGCATTGTGTT TGTTTTT (SEQ ID NO:1151)	TGGTCTATCATGC GAATTAT (SEQ ID NO:1152)
MurE	P22188	GCGTTTGGGGATT TGATGTTC (SEQ ID NO:1153)	CGCGCTAGAGGCT TGTAAAA (SEQ ID NO:1154)	GCCCTGATCCATT CCCCCCT (SEQ ID NO:1155)	CTGTTTTTAGCGTC CCTGTA (SEQ ID NO:1156)	GGCGTTATTAAGC GACATCG (SEQ ID NO:1157)	TTTCACCGGCAAT TTTAGGC (SEQ ID NO:1158)
								AlgA	P07874	GCGTTTTGATTCT GTCTGTTA (SEQ ID NO:1159)	GTAAAAACACCGC TAACGCAT (SEQ ID NO:1160)	GCGTGTTTTCTAA GGGTTCA (SEQ ID NO:1161)	GGAATTTTAACGC TCTTTTT (SEQ ID NO:1162)	AAATCTCTGTGGG CTTAGTG (SEQ ID NO:1163)	AATCAAAAACAA GAGCGTGG (SEQ ID NO:1164)
metL	P19358	GCCCCAGCCCCAT AATACAAA (SEQ ID NO:1165)	GGAGGGCGCAATT AAACATCG (SEQ ID NO:1166)	TCACGCTTTCTAA ATCATCA (SEQ ID NO:1167)	CGCTAATCACATC CTTTCTT (SEQ ID NO:1168)	TGCCCAAAAATCC ACTAACG (SEQ ID NO:1169)	AACGGGTTTGAC ACTGATGA (SEQ ID NO:1170)

Watch 13 (continue)

fus	X16278	GAATGCGGTGGTT TTAGAGAG (SEQ ID NO:1171)	GCGTTTTTAAGAC TGAATACA (SEQ ID NO:1172)	GGGCGATGTGATT GGCGATT (SEQ ID NO:1173)	GGATAGCCTGCCA AAACGCC (SEQ ID NO:1174)	AAGTTTATGCGGG CGAGATT (SEQ ID NO:1175)	GGAGCAATCAGC CATTTTTC (SEQ ID NO:1176)
								FlgE	U09549	CTAGCGATTCAAG GCGATGG (SEQ ID NO:1177)	CGGCCTCCTTCAA ACACATT (SEQ ID NO:1178)	AGCGGGCAGTTTA GGACCAC (SEQ ID NO:1179)	GCATTGATCGCAT TTTTAGCC (SEQ ID NO:1180)	ACGGGTTAGCAGG GCAGAAT (SEQ ID NO:1181)	CAAAAGAGGCGG GTTCATGC (SEQ ID NO:1182)
FliM- setA	M37691	TTTAGAAGTCGTT GATGAGA (SEQ ID NO:1183)	CATACACGCTCAC TTCATCG (SEQ ID NO:1184)	AGTGTGGTCGCCT GTGGTGGAG (SEQ ID NO:1185)	CCCCTAATAGTCT GTCAATCAT (SEQ ID NO:1186)	CAAAAGATTGAAG CAGAAGAGT (SEQ ID NO:1187)	AATGGTTTTCCTA TACCCTTGA (SEQ ID NO:1188)
								FliM- setB	M37691	GAGAGCAAATCCT TATCCAG (SEQ ID NO:1189)	CATACACGCTCAC TTCATCG (SEQ ID NO:1190)	AGTGTGGTCGCCT GTGGTGGAG (SEQ ID NO:1191)	CCCCTAATAGTCT GTCAATCAT (SEQ ID NO:1192)	CAAAAGATTGAAG CAGAAGAGT (SEQ ID NO:1193)	AATGGTTTTCCTA TACCCTTGA (SEQ ID NO:1194)
MurC	U32794	TTGAAACCCCAAA AGTTTTAC (SEQ ID NO:1195)	TCAACTGATAGGT AATATCCC (SEQ ID NO:1196)	GCTAGGATTTATG CCAATTTA (SEQ ID NO:1197)	TACGAGACAAAAT AGGGATTT (SEQ ID NO:1198)	ATAGGCATGCAGA ATTTTTCC (SEQ ID NO:1199)	CCATTACATTTCG CCTC (SEQ ID NO:1200)
								dnaE	M10040	CGATAGATATTGT AGAAGTCA (SEQ ID NO:1201)	GGGCTTGTATTCA TTTTGTAA (SEQ ID NO:1202)	GTTTTAAAAACGC CATAGCCA (SEQ ID NO:1203)	TTCTAAAAGGTGG TAATCTTC (SEQ ID NO:1204)	TAAGTCAAGCCAT AAAACCAAA (SEQ ID NO:1205)	TTTTGGGGTAAAA AGGCTGAA (SEQ ID NO:1206)
SerS	X05017	ATCTTTTTGCCCTT GCTCATA (SEQ ID NO:1207)	AGACAGCACCAGT TTGATAAA (SEQ ID NO:1208)	CAGCCACACTTCA ATGTCTAT (SEQ ID NO:1209)	GTAAGGCGTTAGA AAAATACC (SEQ ID NO:1210)	GCCCCATTAAAAT CCTTTTCT (SEQ ID NO:1211)	AAAGGATACAAG GGGGA (SEQ ID NO:1212)
								gly	P00960	CTCGCTCCATTTTA TCTTTTA (SEQ ID NO:1213)	TTTTTTAGGGAGG ATTGAGAT (SEQ ID NO:1214)	TGTTTGGA AATGC TGGTGATC (SEQ ID NO:1215)	CTTTTTGGGGGAGT TTGACAAG (SEQ ID NO:1216)	TTTGATAAACGCC CACTTTTT (SEQ ID NO:1217)	TTTCAAAACGCTC ACCTTTTG (SEQ ID NO:1218)
Gllx	1.14580	TCTATTCTTTTGAT GCTCTCT (SEQ ID NO:1219)	ATAATGAGTTTGA TCGTTACG (SEQ ID NO:1220)	ACAATAATAGGCT TTGTCTTC (SEQ ID NO:1221)	AATTAGCCCTTAA AATAGATG (SEQ ID NO:1222)	AACAACCGCTAAA ATCAAAC (SEQIDNO:1223)	CTTCAGCGATACT AAAAGAT (SEQ ID NO:1224)
								Sig28 (fliA)	M37691	TAGGGGCGATTGA AAACAGC (SEQ ID NO:1225)	GCTGGATAAGGAT TTGCTCT (SEQ ID NO:1226)	TTTTTGGGGGTAT GCTAAAA (SEQ ID NO:1227)	GGCTGGTAAATAC TGGATAG (SEQ ID NO:1228)	AGGCTATTCAAGG TGGCTAAA (SEQ ID NO:1229)	ATTCTCATCAACG ACTTCTAAA (SEQ ID NO:1230)

Watch 13 (continue)

Sig54	M73443	GCAGTTGGCGGTA TTTGGTG (SEQ ID NO:1231)	GAGAGCGAAGTTT ATGAGAA (SEQ ID NO:1232)	TGATTGTTGGGTA GCTCTCA (SEQ ID NO:1233)	AAAATCGGTCTGA TGCTCTTA (SEQ ID NO:1234)	CTTTCCTTTCGCT TGAAGA (SEQ ID NO:1235)	AAAACAAACGGCA TCAAAAAT (SEQ ID NO:1236)
								Murl	U12405	TTTTCAAGGCGAGG AGGCAGAT (SEQ ID NO:1237)	GCACAAAGACCCC ACCACGAT (SEQ ID NO:1238)	CGCCCGAATGGAT GAGTAGG (SEQ ID NO:1239)	TGCAACAAAAATA CGCCCTT (SEQ ID NO:1240)	TTTTTAAGGGCGT ATTTTTGT (SEQ ID NO:1241)	TGGGTTTTAAGGA ATGTGATG (SEQ ID NO:1242)
dnaB	D26185	CGCGCTCAAAATC CCTAAAT (SEQ ID NO:1243)	GGCCCATTCTTTC GGATATT (SEQ ID NO:1244)	GCCCCATTCCTGTT TTTAGC (SEQ ID NO:1245)	CGCTTTAACGCTC CTTTCAC (SEQ ID NO:1246)	AGCGTTTTTGTAA GGGGGTAT (SEQ ID NO:1247)	TCCCTATCATAGC GTTAGTGC (SEQ ID NO:1248)
								MurG	D10602	CTTAGGGGTTTTT AGCATGAA (SEQ ID NO:1249)	GCACAATTCCCAC ACGCTGC (SEQ ID NO:1250)	CCAAAGCTAAAGC GGTGTTTT (SEQ ID NO:1251)	GCTCATGGATATA AAGGGGTATT (SEQ ID NO:1252)	CTTAGCCCCTTTA GTOTTTA (SEQ ID NO:1253)	CGCAAAAGGGTA GGGGATAA (SEQ ID NO:1254)
lpxC	U32794	TTTTATTTTTAGAA ACGAATC (SEQ ID NO:1255)	CAAACTTATCGCC CTCTCTA (SEQ ID NO:1256)	AAAGATAACGCTA GGATTTCTAC (SEQ ID NO:1257)	TAATTCTACAGAG TGGTTAATGG (SEQ ID NO:1258)	GCGGTCATGGAAT TTTTAGA (SEQ ID NO:1259)	ATTCAAAGAAAG CTGGCTGTCT (SEQ ID NO:1260)
								kdtA	M86305	GCTTGTGGGGGTT GTTTTAT (SEQ ID NO:1261)	GAACCCCCTAAAA TGACAAT (SEQ ID NO:1262)	ACCATGCTCATTA ACGCTAGG (SEQ ID NO:1263)	GTAAGTTTGAGCG GCTAATTC (SEQ ID NO:1264)	AAAAAGAAAGAA GAACTCGTG (SEQ ID NO:1265)	AAAGATACTCCC CTGTGATTA (SEQ ID NO:1266)
lpxB	U09549	CAAAGAAACGCAA AATACAG (SEQ ID NO:1267)	GCATGGTATTCAG CGTTTTC (SEQ ID NO:1268)	GCAGCGGCACAGC GACTTTAG (SEQ ID NO:1269)	CGCCCCCAAAAAG TCGCAGTA (SEQ ID NO:1270)	AAAGGTTTGAAAC AAGAAATCT (SEQ ID NO:1271)	CACTTGAGCGTTA GCAACAAT (SEQ ID NO:1272)
								KO24		GGGGTGTTTGAAA TTGATAGA (SEQ ID NO:1273)	CGCTAGGAGAAAG GAAGGAAA (SEQ ID NO:1274)	CAAGGGCGTTTTT TGGGGTAT (SEQ ID NO:1275)	GGGATTGTTACAG GAAAAGAT (SEQ ID NO:1276)	GGAATACAATAAC GCATAAAT (SEQ ID NO:1277)	GCCTTTTTAGACA ACCCTACT (SEQ ID NO:1278)
KO26		CCCCTAAACTCAA ATCTCAAT (SEQ ID NO:1279)	GCTAGAAATGCCA TGAGAAAG (SEQ ID NO:1280)	GCGATTATGGGGT ATTTATTG (SEQ ID NO:1281)	TTATTGTGGAGTT GCTTGTCA (SEQ ID NO:1282)	TATGCGGCTCATC CTATTAAA (SEQ ID NO:1283)	CCCTAAATCCAA ATCAAGCAG (SEQ ID NO:1284)

Genomic DNA prepared from helicobacter pylori HpJ99 strain (ATCC 55679) was used as a source of template DNA for PCR (polymerase chain reaction) amplification of ORF (latest methods in molecular biology, edited by John Wiley and Sons, Inc., F.Ausubel et al, 1994). Preparation of genomic DNA from H.pylori, see example I, PCR amplification was carried out by loading 10 ng of HpJ99 genomic DNA into reaction vials containing: 10mM Tris pH8.3, 50mM 、2mM 2 micromolar synthetic oligonucleotide primers (forward = F1, reverse = R1), 0.2mM each deoxynucleotide triphosphate (dATP, dGTP, dCTP, dTTP), 1.25 units of thermostable DNA polymerase (Amplitaq, Roche Molecular Systems, Inc., Branchburg, NJ, USA) in a total reaction volume of 40 microliters. PCR was performed using a Perkin Elmer Cetus/GeneAmp System9600 thermal cycler. The thermocycling conditions used to obtain amplified DNA products for each knock-out target are shown in Table 14.

TABLE 14

PCR conditions

MurC

Heat denaturation at 94 ℃ for 2 min;

at 94 deg.C, 15 seconds, 48 deg.C, 15 seconds, 72 deg.C, 1 minute and 30 seconds, for 25 cycles;

finally extension at 72 ℃ for 20 minutes.

Sig54

Heat denaturation at 94 ℃ for 2 min;

at 94 deg.C, 15 seconds, 50 deg.C, 15seconds, 72 deg.C, 1 minute and 30 seconds, for 25 cycles;

finally extension at 72 ℃ for 20 minutes.

lpxC

Heat denaturation at 94 ℃ for 2 min;

32 cycles of 94 ℃ for 15 seconds, 50 ℃ for 15 seconds, 72 ℃ for 1 minute and 30 seconds;

finally extension at 72 ℃ for 20 minutes.

KO24、KO26、KO27

Heat denaturation at 94 ℃ for 2 min;

25 cycles of 94 ℃ for 15 seconds, 50.5 ℃ for 20 seconds, 72 ℃ for 2 minutes;

finally extension at 72 ℃ for 20 minutes.

KO29, 26kDa protein

Heat denaturation at 94 ℃ for 2 min;

28 cycles of 94 ℃ for 15 seconds, 50.5 ℃ for 20 seconds, 72 ℃ for 2 minutes;

and finally extended at 72 for 20 minutes.

DnaE、Glvcvl

Heat denaturation at 94 ℃ for 2 min;

at 94 deg.C, 15 seconds, 51 deg.C, 15 seconds, 72 deg.C, 1 minute and 30 seconds, for 20 cycles;

finally extension at 72 ℃ for 20 minutes.

Gltx

Heat denaturation at 94 ℃ for 2 min;

25 cycles of 94 ℃ for 15 seconds, 51 ℃ for 15 seconds, 72 ℃ for 1 minute and 30 seconds;

finally extension at 72 ℃ for 20 minutes.

KO28

Heat denaturation at 94 ℃ for 2 min;

25 cycles of 94 ℃ for 15 seconds, 51 ℃ for 15 seconds, 72 ℃ for 2 minutes;

finally extension at 72 ℃ for 20 minutes.

KO30

Heat denaturation at 94 ℃ for 2 min;

at 94 ℃ for 15 seconds, at 51.5 ℃ for 15 seconds, at 72 ℃ for 1 minute and 45 seconds, performing 25 cycles;

finally extension at 72 ℃ for 20 minutes.

MurI、MurG

Heat denaturation 94 for 2 min;

25 cycles of 94 ℃,15 seconds, 52 ℃,15 seconds, 72 ℃,1 minute and 30 seconds;

finally extension at 72 ℃ for 20 minutes.

DnaB、KdtA、LpxB

Heat denaturation at 94 ℃ for 2 min;

27 cycles of 94 ℃ for 15 seconds, 52 ℃ for 15 seconds, 72 ℃ for 1 minute and 30 seconds;

finally extension at 72 ℃ for 20 minutes.

Tsf、FlgE、FliM、Sig28、MurB

Heat denaturation at 94 ℃ for 2 min;

30 cycles of 94 ℃ for 15 seconds, 52 ℃ for 15 seconds, 72 ℃ for 1 minute and 30 seconds;

finally extension at 72 ℃ for 20 minutes.

PpiB

Heat denaturation at 94 ℃ for 2 min;

30 cycles of 94 ℃ for 15 seconds, 52 ℃ for 15 seconds, 72 ℃ for 2 minutes and 30 seconds;

finally extension at 72 ℃ for 20 minutes.

MurD、MurE、Al gA、MetL、FusA、SerS、Rnh

Heat denaturation at 94 ℃ for 2 min;

30 cycles of 94 ℃ for 15 seconds, 55 ℃ for 15 seconds, 72 minutes for 1 minute for 30 seconds;

finally extension at 72 ℃ for 20 minutes.

After completion of the thermocycling reaction, each amplified DNA sample was visualized on a 2% TAE agarose gel stained with ethidium bromide (latest methods in molecular biology, John Wiley and Sons, Inc., edited by F.Ausubel et al, 1994) to confirm that a single product of the desired size had been generated from the reaction. The amplified DNA was then washed and purified using Qiagen Spin PCR purification kit (Qiagen, Gaithersburg, Md., USA).

The PCR product was cloned into pT7Blue T-vector (Catalog #69820-1, Novagen, Inc. Madison, Wis., USA) using a TA cloning strategy (latest methods in molecular biology, John Wiley and Sons, Inc., edited by F.Ausubel et al, 1994). Ligation of the PCR products into the vector was accomplished by mixing 6-fold molar excess of the PCR products with 10 nanograms of pT7BlueT-vector (Novagen). To a final reaction volume of 10. mu.l were added 1. mu.l of T4DNA ligase buffer (New England BioLabs, Beverly, MA, USA) and 200 units of T4DNA ligase (New England BioLabs) and ligated for 16 hours at 16 ℃.

In brief, 1 microliter of ligation reaction was mixed with 40 microliters of electrocompetent cells and subjected to high voltage shock (25. mu.F, 2.5kv, 200 ohms) and then the sample was placed in 0.45ml of SOC medium (0.5% yeast extract, 2.0% tryptone, 10 mM) in either Xll-Blue or DH5 α E.coli cells which were electrocompetent (Clontech Lab., Inc., Palo Alto, CA, USA) 、2.5mM 、10mM 、10mM And 20mM glucose) at 37 ℃ for 1 hour. The samples were then plated on LB (10 g/l bacto tryptone, 5 g/l bacto yeast extract, 10 g/l NaCl) plates containing 100. mu.g/ml ampicillin, 0.3% X-gal and 100. mu.g/ml IPTG. The plates were incubated at 37 ℃ overnight. Ampicillin resistant colonies were selected for white coloration and cultured in 5ml of liquid LB containing 100. mu.g/ml ampicillin. And plasmid DNA was isolated using Qiagen miniprep (Qiagen, Gaithersburg, Md., USA).

To confirm that the correct H.pylori DNA insert has been cloned, these pT7Blue plasmid DNAs were used as templates for PCR amplification of the cloned insert and the same forward and reverse primers (F1 and R1) used for the initial amplification of the J99 H.pylori sequence were used. The correct insert was cloned by observing the correct size primers and PCR products on a 2% TAE, ethidium bromide stained agarose gel. From 2 to 6 such validated clones were obtained from each knock-out target and stored at-70 ℃. To reduce PCR errors, these confirmed cloned plasmid DNAs were mixed and used in the subsequent cloning steps.

The sequence of the gene/ORF was again used to design a second pair of primers (F2 and R2), the 2 nd pair of primers being located on either side of the region of H.pylori DNA to be disrupted or deleted (up to 250 bp) within the ORF, but in opposite orientation to each other. The previously isolated mixture of cloned circular plasmid DNA was used as template for this round of PCR, since the amplification direction of the pair of deletion primers was in opposite directions, the ORF part between the primers would not be contained in the resulting PCR product, which is a linear DNA, helicobacter pylori DNA at both ends, and pTTBlue vector backbone between them, thus in principle producing a partial deletion of the ORF, and the PCR product was visualized on a 1% TAE, sniffed ethidium stained agarose gel to demonstrate that a single product of the correct size was amplified.

Using the previously employed TA cloning method (molecule)A kanamycin resistance cassette (Labigue-Roussel et al, (1988) journal of bacteriology 170, 1704-Page) was ligated into this PCR product. The kanamycin cassette containing a kanamycin resistance gene of Campylobacter was obtained by EcoRI digestion of the recombinant plasmid pCTB8: kan (Cover et al, J. Biochem. 269, 10566-10573). The appropriate fragment (1.4kb) was isolated on a 1% TAE gel and isolated using the QIAquick gel extraction kit (Qiagen, Gaithersburg, Md., USA). The fragment was end-repaired by Klenow filling-in method, which comprises mixing 4 ug of DNA fragment with 1. mu.l of 0.5mM dATP, dGTP, dCTP, dTTP, 2. mu.l of K1enow buffer (New England Biolabs) and 5 units of Klenow DNA polymerase I (Klenow) large fragment (New England Biolabs) in a total reaction volume of 20. mu.l, incubating at 30 ℃ for 15 minutes, and then heating at 75 ℃ for 10 minutes to inactivate the enzyme. The end-blunted kanamycin cassette was then purified by a QIAquick column (Qiagen, Gaithersburg, Md., USA) to remove nucleotides. Then 5. mu.g of end-blunted kanamycin cassette were mixed with 10mM Tris pH8.3, 50mM 、2mM 5 units of DNA polymerase (Amplitaq, Roche Molecular systems Inc. Braanchbury, NJ, USA) and 20. mu.l of 5mM dTTP were mixed in a total reaction volume of 100. mu.l and reacted at 37 ℃ for 2 hours to generate an "OTO" overhang. The "Kan-T" cassette was purified using QIAquick columns (Qiagen, Gaithersburg, Md., USA). The PCR product with the deletion primers (F2 and R2) was ligated to the Kan-T cassette by: the primer-deleted PCR product was mixed at 10-25 ng with 50-75 ng Kan-T cassette DNA, 1. mu.l 10 XT 4DNA ligation reaction mixture, 0.5. mu.l T4 ligase (New England Biolabs, Beverly, Mass., USA) in a total reaction volume of 10. mu.l and incubated at 16 ℃ for 16 hours.

The ligation products were transformedinto XLL-Blue or DH5 α E.coli cells by the electrotransformation method described above, after recovery in SOC, the cells were plated on LB plates containing 100. mu.g/ml ampicillin, grown overnight at 37 ℃ and then these plates were replicated on plates containing 25. mu.g/ml kanamycin and grown overnight.

Several experiments were performed on these plasmids using PCR amplification to confirm that kanamycin had been inserted into the H.pylori gene/ORF and to determine the direction of insertion of the kanamycin resistance gene relative to the H.pylori gene/ORF. To confirm that the kanamycin cassette has been inserted into the H.pylori sequence, plasmid DNA was used as template for PCR amplification and primers were used with the primer pair originally used for cloning the H.pylori gene/ORF (F1 and R1). The correct PCR product is the size of the deleted gene/ORF but with the addition of a 1.4 kilobase kanamycin cassette. To prevent the potential polar effect of the kanamycin resistance cassette on H.pylori gene expression, the orientation of the kanamycin resistance gene relative to the knockout gene/ORF was determined and finally the insert in both orientations was used for H.pylori transformation (see below). To determine the direction of insertion of the kanamycin resistance gene, primers ("Kan-1" 5'-ATCTTACCTATCACCTCAAAT-3' (SEQ ID NO:1285) and "Kan-2" 5'-AGACAGCAACATCTTTGTGAA-3' (SEQ ID NO:1286)) were designed from both ends of the kanamycin resistance gene. By using each cloning primer (F1 and R1) and each Kan primer (four combinations of primers), the orientation of the kanamycin cassette relative to the H.pylori sequence was determined. Positive clones were classified as either "A" orientation (in which the H.pylori gene and the kanamycin resistance gene are transcribed in the same direction), or "B" orientation (in which the H.pylori gene and the kanamycin resistance gene are transcribed in opposite directions). Clones from the same orientation (A or B) were pooled and transformed with H.pylori independently of each other.

Transformation of plasmid DNA into H.pylori cells

Two helicobacter pylori strains were used for transformation: ATCC55679, and AH 224. ATCC55679 is a clinical isolate providing DNA from which a database of H.pylori sequence has been obtained, and AH224 is an isolate which is introduced into and colonizes the stomach of mice. Cells used for transformation were 10% at 37 ℃% Growth at 100% humidity either on sheep blood agar plates or in brookfield broth. Cells were grown to logarithmic growth phase and were determined to be "healthy" (active cells) and free of contamination by microscopic examination, and if grown on plates, cells were harvested by scraping the plates with a sterile loop, suspended in 1ml of buchner broth, centrifuged (1 min, eppendorf centrifuge top speed), and resuspended in 200ul of buchner broth. If grown in Brookfield broth, the cells are centrifuged (using a Beckman TJ6 centrifuge for 15 minutes at 3000 rpm), the cell pellet is resuspended in 200 microliters of Brookfield broth, and 1 aliquot of the cells is taken to determine the optical density at 600nm, which is used to calculate the concentration of the cells. 1 aliquot (1 to 5 OD)₆₀₀Unit/25 microliter) of resuspended cells were plated on pre-warmed sheep blood agar plates at 37 ℃ and 6% After further incubation at 100% temperature for 4 hours, 10. mu.l of plasmid DNA (100. mu.g/ml) was added to the cells. A positive control (plasmid with ribonuclease H gene interrupted by kanamycin gene) and a negative control (no plasmid DNA) were also performed. The plate is heated at 37 ℃ and 6% The culture was continued for 4 hours, then the cells were spread out on a plate with a cottonswab soaked in Brookfield broth and incubated at 37 ℃ for 6% Growth for 20 hours, then the bacteria were transferred to a medium containing 25. mu.g/ml kanamycinSheep blood agar plates, and 6% at 37% Incubate for 3 to 5 days at 100% humidity. If colonies appeared, they were picked and grown into plates on fresh sheep blood plates containing 25. mu.g/ml kanamycin.

Three sets of PCR (three experiments) were performed to confirm that these transformed colonies were generated by homologous recombination at the appropriate chromosomal sites. The template for PCR (DNA from the colonies) was obtained by a flash boiling preparation method. An aliquot of the colony (spotted with a toothpick) was taken into 100. mu.l of a solution containing 1% Triton-X-100, 20mM Tris, pH8.5 and boiled for 6 minutes, an equal volume of phenol: chloroform (1: 1) was added and shaken well, the mixture was centrifuged for 5 minutes, and the supernatant was used as a DNA template for PCR, while using the following combination of primers, to confirm homologous recombination at the appropriate chromosomal location.

TEST1 PCR used F1 and R1 primers (cloning primers originally used to amplify the gene/ORF). A positive result of homologous recombination at the correct chromosomal location should show a single PCR product of the expected size of the deleted gene/ORF plus the 1.4 kilobase kanamycin cassette. The exact size of the PCR product for the gene/ORF demonstrates that the gene has not been knocked out and that the transformants are not the result of homologous recombination at the correct chromosomal location.

TEST2 used F3 (primers designed from the sequence upstream of the gene/ORF) and primers Kan-1 or Kan-2 (designed from the end of the kanamycin resistance gene), the selection of Kan-1 or Kan-2 being based on whether the plasmid DNA used was in the "A" or "B" orientation. A positive result of homologous recombination at the correct chromosomal position of the gene/ORF sequence upstream of the kanamycin resistance gene should show a single PCR product of the expected size from the position of F3 to the insertion position of the kanamycin resistance gene. No PCR product or PCR products of different sizes demonstrated that the plasmid did not integrate into the correct site and the gene was not knocked out.

TEST3 used R3 (primers designed from the downstream sequence of the gene/ORF) and Kan-1 or Kan-2, Kan-1 or Kan-2 were selected based on whether the plasmid DNA used was in the "A" or "B" orientation. A positive result of homologous recombination at the correct position on the chromosome downstream of the kanamycin resistance gene should show a single PCR product, the expected size of which is from the insertion position of the kanamycin resistance gene to the position downstream of R3. Likewise, no PCR product or PCR products of different sizes demonstrated that the plasmid did not integrate into the correct site and the gene was not knocked out.

Genes that are not essential for survival in vitro generally result in as many transformants as observed on the rnase H gene positive control. Any transformants that showed a positive result for all three experiments could be concluded that the gene is not essential for in vitro survival.

The genes essential for in vitro survival generally show few transformants, all transformants should be screened, and a negative result in any of the three tests can conclude that the gene is not disrupted and is essential for in vitro survival.

In the case where there are no colonies in both independent transformation experiments, but transformants can be produced using the disrupted ribonuclease H plasmid DNA, further analysis of plasmid DNA from the population of transformants by PCR before plating for colony formation confirmed that it can enter the cells and homologous recombination can be formed at the correct site, briefly, incubation of plasmid DNA according to the above transformation method, extraction of DNA from the cells immediately after incubation of the plasmid with H.pylori cells, and use of the DNA as a template for both TEST2 and TEST3, positive results for TEST2 and TEST3 will confirm that plasmid DNA can enter the cells and recombine homologously at the correct location in the chromosome, indicating that the gene is essential if TEST2 and TEST3 are positive, but neither can obtain viable transformants, and that the cells cannot form colonies if the gene is disrupted.

The genes used in these experiments proved to be essential, non-essential, under study. As shown in table 15.Watch 15

Gene/ORF Outline of knockouts
				Gene	Login number	Pathway(s)	Condition of the condition
rnh	P23329	Transcription	Is not necessarily required
				ppiB	P29820	Translation	Is not necessarily required
tsf	P34828	Translation	Is required to
				MurD	P14900	Cell membrane	Is required to
MurE	P22188	Cell membrane	Is required to
				AlgA	P07874	Virulence/colonization	Is not necessarily required
metL	P19358	Amino acid biosynthesis aspartate family	Is not necessarily required
				fusA	X16278	Translation	Is required to
FlgE	U09549	Virulence/colonization	Non-essential-motor impairment
				FliM	M37691	Virulence/colonization	Non-essential-motor impairment
MurC	U32794	Cell membrane	Is required to
				dnaE	M10040	DNA replication	Is required to
serS	X05017	Translation	Is required to
				gly	P00960	Translation	Is required to
gltX	L14580	Translation	Is required to
				sig28(fliA)	M37691	Function control	Non-essential-motor impairment
sig54		Function control	Non-essential-motor impairment
				MurI	U12405	Cell membrane	Is required to
dnaB	D26185	DNA replication	In the research
				MurG	D10602	Cell membrane	In the research
lpxC/envA	U32794	Cell membrane	In the research
				kdtA	M86305	Cell membrane	In the research
lpxB	U09549	Cell membrane	In the research
				KO24		Thiolase sample	In the research
KO26		Histone-like	In the research
				KO27		Respiratory chain NADH dehydrogenase-like	In the research

VIII: cloning, purification and characterization of the Gene encoding peptidyl-propyl-cis-trans-isomerase of helicobacter pylori

The H.pylori genome contains an Open Reading Frame (ORF) encoding 170 amino acids, which is found to be homologous to the ppi gene (NCBI accession number P29820) of a species of Synechococcus (synechococcus) (strain PCC 7942). Therefore, to determine whether the ORF encodes a protein with PPiase activity, we cloned the gene by Polymerase Chain Reaction (PCR) amplification, overexpressed in E.coli, and purified the protein to homogeneity. For ease of purification, a polyhistidine tag was added to the N-terminus of the ORF. We developed a simple assay using PPIase to assess protein folding function for later use as a high throughput drug screen.

Currently, the PPIase species are divided into three families that are not related to each other: cyclophilins, FK 506-binding (FKBPs) and microcins. Although PPIase mutants have been reported in yeast and Drosophila, efforts to isolate disrupted mutants in E.coli have been unsuccessful (Shieh, B.H. et al (1989) Nature 338, pp.67-70). This indicates that this activity is essential for the survival of the bacteria.

Cloning, expression and protein purification

To facilitate cloning, expression and purification of ppi from H.pylori, an efficient gene expression system pET system was used for cloning and expression of recombinant ppi in E.coli. In this study, the sequence of helicobacter pylori ppi contained a DNA sequence encoding a histidine tag fused 5' to the full-length gene, since the protein product of this gene did not contain a signal sequence and was expressed as a cytoplasmic protein.

We used the 5' end to the ppi geneOligonucleotide synthesis primer (5'-TTATGGATCCAAACCAATTAAAACT-3') (SEQ ID NO:1287) which is terminal specific and which encodes a BamHI site at its 5 ' extreme and primer (5'-TATCTCGAGTTATAGAGAAGGGC-3') (SEQ ID NO:1288) which is specific for the 3 ' end of the ppi gene and which encodes an XhoI site at its 5 ' extreme. Genomic DNA prepared from the H.pylori J99 strain was used as a source of template DNA for PCR amplification reactions (latest methods in molecular biology, edited by John Wiley and Sons, Inc., F.Ausubel et al, 1994). To amplify the DNA sequence containing the helicobacter pylori ppi gene, genomic DNA (50 ng) was loaded into a reaction vial containing: 2mM 1 micromolar synthetic oligonucleotide primers (forward and reverse primers) complementary to the specific H.pylori ORF and to either flank thereof, 0.2mM of each deoxynucleotide triphosphate, i.e.dATP, dGTP, dCTP, dTTP, 2.5 units of thermostable DNA polymeraseThe synthase (Amplitaq, Roche Molecular Systems, Inc., Branchburg, NJ, USA) was reacted in a total volume of 100. mu.l. The following thermal cycling conditions were used to obtain amplified DNA products for each ORF using a Perkin Elmer Cetus/GeneAmp PCRSystem9600 thermal cycler.

Amplification conditions for helicobacter pylori ppiB gene

Heat denaturation at 94 ℃ for 2 min;

2 cycles of 94 ℃, 15 seconds, 32 ℃, 15 seconds, 72 ℃,1 minute and 30 seconds;

25 cycles of 94 ℃ for 15 seconds, 56 ℃ for 15 seconds, 72 ℃ for 1 minute and 30 seconds;

finally extension was carried out at 72 ℃ for 6 minutes.

After completion of the thermocycling reaction, the amplified DNA was washed and purified using the Qiaquick Spin PCR purification kit (Qiagen, Gaithersburg, Md., USA). The amplified DNA sample is digested with restriction enzymes such as BamI and XhoI (New England BioLabs, Beverly, MA, USA) (New methods in molecular biology, John Wiley and Sons, Inc., edited by F.Ausubel et al, 1994). The DNA samples were then electrophoresed on a 1.0% NuSeive (FMC BioProducts, Rockland, ME, USA) agarose gel. The DNA was treated with ethidium bromide and visualized by excitation with long-wave UV light. DNA contained in the band separated from the gel was purified from the gel using Bio 101 GeneClean kit (Bio 101Vista, Calif., USA).

The cloning, transformation, expression, and purification of the PPI gene was performed essentially as described in examples II and III above.

Analysis of PPIase Activity

Analysis of PPIase was performed essentially as described by Fisher (Fisher et al, 1984, "biomed. Biochim. acta" 43, 1011. pp. 1111.) this assay measures cis-trans isomerisation of the Ala-Phe bond in the test peptide N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide (Sigma # S-7388, lot #84H 5805.) this assay was coupled with α -chymotrypsin, where proteolytic cleavage of the test peptide occurs only in the case where Ala-Phe is trans, in the assay, conversion of the test peptide to the trans isomer was followed by observation at 390nM on a Beckman Model Du-650 spectrophotometer. data was collected using an average scan time of 0.5 seconds for the clock. analysis was performed in 35mM HEPES, pH8.0, with a total reaction volume of 400. mu.l and with 10uM of α -trypsin (1-5 from calf pancreas; Sigma # C-23, Sigma # 2H-p.) the reaction was started with a mixture of PPIpase containing 10. Pro-Phe-Pro-p-nitroanilide (1-5, 10 mM).

PPise assay in crude and crude bacterial extracts

Logarithmic growth phase (OD) from 50ml₆₀₀1) of helicobacter pylori (strain J99) and resuspended in lysis buffer containing the following protease inhibitors: 1mM PMSF, and aprotinin, pepstatin, leupeptin, TCLK, TPCK and soybean trypsin inhibitor each at 10 ug/ml. The suspension was freeze-thawed repeatedly (-70 ℃ for 15 min, then 30 min at room temperature) three times, then sonicated (3 20 second hits). The lysate was centrifuged (12,000 g.times.30 min) and the supernatant was used for the PPiase activity assay.

Results

PPI from H.pylori was expressed in E.coli using Novagen's pET28b expression vector (cat # 69832-1). Passage of bacterial cellsDisruption was performed by cavitation in a microfluidics cell disruption chamber, and the expressed recombinant protein was isolated from the soluble fraction. The recombinant PPI is expressed at a level that produces 100mg of protein. The recombinant protein can be used Purification to homogeneity by chelate chromatography and gel filtration. On sodium dodecyl sulfate polyacrylamide gel, the recombinant protein migrated as a single band of 21kDa, consistent with a molecular weight of 20,975 as predicted by the gene sequence.

PPIase activity was assayed using the chromogenic tetrapeptide substrate N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide. An initial rate of 4.9umol/min/mg protein was detectable with pure enzyme (FIG. 5). This corresponds to 1.6 seconds^-1K of_catAnd is similar to the data obtained for E.coli PPIase (Lin, J. and Walsh, C.T (1990) Proc. Natl.Acad.Sci.USA 87, 4028 + 4032) and from pig kidney (Fisher, G. (1989) Nature 337, 476 + 478).

The recombinant protein has a size of 2.06X 10 when the assay is performed at 25 ℃⁹M^-1S^-1High catalytic efficiency. These catalytic values are 1 to 2 orders of magnitude higher than other identified ppiases. However, in those studies, the ppiase analysis was performed at 10 ℃, which may be responsible for the differences. This catalytic efficiency is very close to the "most kinetically elegant" upper limit of enzyme diffusion (Albery, W.J. and Knowles, J.R (1976) biochemistry, Vol.15, 5631-5640) and suggests that H.pylori PPIase is a highly efficient catalyst for the Ala-Pro bond of oligopeptide substrates, at least in one measurement.

We also measured the presence of PPIase in H.pylori extracts. As with the test with the recombinant protein, we detected PPIase activity, which was dependent on the concentration of the added extract (FIG. 6).

These results show that PPIase activity can be measured in H.pylori extracts or recombinant proteins in E.coli, and that high catalytic efficiency also demonstrates that H.pylori enzymes such as PPIase can be expressed in E.coli at high levels and in highly active forms. Such high purified protein yields provide conditions for various high throughput drug screening assays.

Cloning, purification and analysis of IX Gene encoding Glu racemase of helicobacter pylori

The H.pylori genome contains a 225 amino acid Open Reading Frame (ORF) which is found to be homologous to the glutamate racemase gene (dga) of Staphylococcus haemolyticus (NCBI accession number U12405) and the mur I gene encoding glutamate racemase activity in E.coli. To assess whether this H.pylori ORF encodes a protein with glutamate racemase activity, we cloned the gene by polymerase chain reaction amplification and overexpressed in E.coli, purifying the protein to homogeneity in appearance. We have developed a simple assay of glutamate racemase activity leading to the isomerisation of D-glutamate and L-glutamate, to facilitate purification and subsequent use as a high throughput drug screen.

By gene disruption studies, we have found that this ORF in H.pylori is essential for the survival of H.pylori cells in laboratory culture (see example VII above). Therefore, inhibition of the enzyme activity is expected to be lethal to the organism, and such inhibitors are useful as antimicrobial therapeutic agents for human infectious diseases.

Cloning of the mur I Gene of helicobacter phylum encoding glutamate racemase

We isolated 765 base pair DNA sequence encoding the H.pylori mur I gene by PCR cloning. We used a synthetic oligonucleotide primer (5'-AAATAGTCATATGAAAATAGGCGTTTTTG-3' (SEQ ID NO:1289)) encoding an NdeI restriction site and the 5 'end of mur I gene and a primer (5'-AGAATTCTATTACAATTTGAGCCATTCT-3'(SEQ ID NO:1290)) encoding an EcoRI restriction site and the 3' end of mur I gene to amplify mur I gene of H.pylori using genomic DNA prepared from H.pylori J99 strain as a template for PCR amplification reaction (latest methods in molecular biology, John Wiley and Sons, Inc., edited by F.Ausubel et al, 1994). To amplify the DNA sequence containing the mur I gene, genomic DNA (25 ng) was loaded into two reaction vials containing the following componentsEach of (a) to (b): 1.0 micromoles of each synthetic oligonucleotide primer, 2.0mM 、0.2mM of each deoxynucleoside triphosphate (dATP, dGTP, dCTP)&dTTP), 1.25 units of thermostable DNA polymerase (Amplitaq, Roche Molecular Systems, Inc., Branchburg, NJ, USA), in a total reaction volume of 50. mu.l. The following thermal cycling conditions were used to obtain amplified DNA products of the mur I gene using a Perkinelmer Cetus/GeneAmp PCR System9600 thermal cycler.

Amplification conditions for helicobacter pylori mur I

Heat denaturation at 94 ℃ for 2 min;

2 cycles of 94 ℃ for 15 seconds, 30 seconds, 72 ℃ for 15 seconds;

at 94 deg.C, 15 seconds, 53 deg.C, 30 seconds, 72 deg.C, 15 seconds, 23 cycles;

the reaction was terminated after 20 minutes at 72 ℃.

After completion of the thermocycling reaction, the amplified DNA was washed and purified using the Qiaquick spin PCR purification kit (Qiagen, Gaithersburg, Md., USA). The amplified DNA samples were digested with restriction enzymes such as Nde I and EcoR I (New England BioLabs, Beverly, MA, USA) (latest methods in molecular biology, supra). DNA samples from each of the two reaction mixtures were mixed and electrophoresed on a 1.0% SeaPlaque (FMC BioProproducts, Rockland, ME, USA) agarose gel. The DNA was treated with ethidium bromide and visualized by excitation with long-wave UV light. DNA encoding the H.pylori mur I gene was isolated and amplified from the gel strip and purified using the Bio 101 GeneClean kit (Bio 101Vista, CA, USA).

Cloning pyloric helicobacterium DNA sequence into pET-23 prokaryotic expression vector

pET-23b vectors can be propagated in any E.coli K-12 strain, such as HMS174, HB101, JM109, DH5 α, etc., for cloning or plasmid preparation, the hosts used for expression include E.coli containing a chromosomal copy of the T7RNA polymerase gene, these hosts are lysogens of bacteriophage DE3, DE3 is a lambda derivative carrying the Lac I gene, the LacUV5 promoter and the T7RNA polymerase gene, T7RNA polymerase is induced by the addition of isopropyl- β -D-thiogalactoside (IPTG), T7RNA polymerase can transcribe any plasmid carrying its target gene, for example, pET-28 b. the strains commonly used in laboratories include BL21(DE3) (Studier, F.W., Rosenberg, A.H., Dunn, J.J., and Dubendaff, J.W (1990) methods 185, pp.60-89).

pET-23b vector (Novagen, Inc., Madison, I, USA) was prepared for cloning by Nde I and EcoR I digestion (latest methods in molecular biology, supra). After digestion, the mur I gene-carrying DNA fragment amplified and agarose gel purified was cloned (latest methods in molecular biology, supra) into the digested pET-23b expression vector, and the ligation reaction was used to transform the BL21(DE3) strain of E.coli.

Transformation of competent bacteria with recombinant plasmids

Competent cells of E.coli strain BL21 or E.coli strain BL21(DE3) were transformed with the recombinant pET23-mur I expression plasmid carrying the cloned helicobacter pylori sequence according to standard methods (latest methods in molecular biology, supra). Briefly, 1 microliter of ligation reaction was mixed with 50 microliters of electrocompetent cells, then subjected to high voltage, after which the sample was placed in 0.45 ml of SOC medium (0.5% yeast extract, 2.0% tryptone, 10 mM) 、2.5mM 、10mM 、10mM And 20mM glucose) at 37 ℃ for 1 hour. The samples were then plated on LB agar plates containing 100. mu.g/ml ampicillin for overnight growth. Transformed colonies of BL21 were then picked and analyzed as described below to evaluate the cloned inserts.

Identification of recombinant pET expression vector with helicobacter pylori sequence

The single BL21 clone transformed with recombinant pET-23-mur I was analyzed by PCR amplification of the insert of the clone using the same forward and reverse primers specific for each H.pylori sequence used in the original PCR amplification cloning reaction. Successful amplification confirmed the integration of the H.pylori sequence in the expression vector (recent methods in molecular biology, supra).

Isolation and preparation of plasmid DNA from BL21 transformant

Colonies with the pET23-mur I vector were picked and incubated overnight in 5ml LB broth with 100. mu.g/ml ampicillin. The following day, plasmid DNA was isolated and purified using Qiagen plasmid purification (Qiagen Inc., Chatsworth, Calif., USA).

Cloning and expression of the E.coli groE operon

Co-expression of the E.coli mur I gene with genes in the E.coli groE operon has been shown to reduce the formation of insoluble inclusion bodies containing recombinant glutamate racemase (Ashiuchi, M., Yashimura, T., Kitamura, T., Kawata, Y., Nagai, J., Gorlator, S., Esaki, N., and Soda, K.,1995, J. biochem. 117, page 495-498). The GroE operon encodes 2 proteins, GroES (97 amino acids) and GroEL (548 amino acids), which are chaperones that together assist in the folding of nascent polypeptide chains (F.Ulrich Hartl,1996, Nature London 381, pp.571-580).

2210 bp DNA sequence encoding the groE operon of E.coli (NCBI accession number)X07850) was isolated using pcr amplification cloning. We used a synthetic oligonucleotide primer (5'-GCGAATTCGATCAGAATTTTTTTTCT-3') (SEQ ID NO:1291) encoding the EcoRI restriction site and the 5 'end of the groE operon containing the endogenous promoter region of the groE operon, and a primer (5'-ATAAGTACTTGTGAATCTTATACTAG-3') (SEQ ID NO:1292) encoding a ScaI restriction site and the 3' end of the groEL gene in the groE operon, to amplify the groE operon of E.coli, using genomic DNA prepared from E.coli MG1655 as a template for the PCR amplification reaction (latest methods in molecular biology, supra). To amplify the DNA sequence containing the GroE operon of E.coli, the genome (12.5 ng) was loaded into each of two reaction tubes containing: 0.5 micromoles of each oligonucleotide primer, 1.5mM 0.2mM of each deoxynucleoside triphosphate (dATP, dGTP, dCTP)&dTTP), 2.6 units of thermostable DNA polymerase (Expanded highFidelity PCR System, Boehringer Mannheim, Indianapolis, Indiana). The total volume of the reaction was 50. mu.l. The following thermal cycling conditions were used to obtain the amplified DNA product of the groE operon using a Perkin Elmer Cetus/GeneAmp PCR System9600 thermal cycler.

Amplification and cloning conditions for E.coli groE protein

Heat denaturation at 94 ℃ for 2 min;

2 cycles of 94 ℃, 15 seconds, 30 seconds, 72 ℃,2 minutes;

at 94 deg.C, 15 seconds, 55 deg.C, 30 seconds, 72 deg.C, 2 minutes, 23 cycles;

the reaction was completed after 8 minutes at 72 ℃.

After completion of the thermocycling reaction, the amplified DNA was washed and purified using the Qiaquick spin PCR purification kit (Qiagen, Gaithersburg, Md., USA). The amplified DNA samples were digested with restriction enzymes such as EcoR I and Sca I (New England BioLabs, Beverly, MA, USA) (latest methods in molecular biology, supra). DNA samples from both reaction mixtures were mixed and electrophoresed on a 1.0% SeaPlaque (FMCBioproducts, Rockland, ME, USA) agarose gel. The DNA was treated with ethidium bromide and visualized by excitation with long-wave UV light. DNA contained in the band separated from the gel was purified with a Bio 101 GeneClean kit (Bio 101Vista, CA, USA).

The EcoRI to ScaI DNA fragment containing the Escherichia coli groE operon was cloned into the same site of pACYC184 expression vector (New England BioLabs, Beverly, MA, USA) to prepare pACYCl 84-groE. ColiBL21(DE3) strain was transformed with pACYC 184-groE. Tetracycline-resistant transformants were isolated which were capable of over-expressing molecular weights of about 14,000(GroES) and about 60,000 (GroEL).

Transformation of E.coli Strain BL21(DE3) carrying E.coli plasmid pACYC-groE

Competent cells, derived from a clone of strain BL21(DE3) harboring the pACYC-groE plasmid, were transformed with 50ng of plasmid DNA pET23-mur I, which was isolated as described above (latest methods in molecular biology, supra). BL21(DE3) clones containing both the pACYC184-groE expression plasmid and the pET23-mur I plasmid were isolated and used for the expression of recombinant glutamate racemase as described below.

Expression of recombinant helicobacter pylori mur I

BL21(DE3) bacterial clones containing both the pACYC-groE expression plasmid and the pET23-mur I plasmid were cultured in LB broth supplemented with 1.0mM D, L-glutamic acid and 100. mu.g/ml ampicillin and 10. mu.g/ml tetracycline at 30 ℃ until absorbance at 600nm was 0.5 to 1.0 O.D. units, at which time cells were cultured overnight with isopropyl- β -D-thiogalactoside (IPTG) added to the culture to a final concentration of 1.0 mM. to induce expression of the H.pylori recombinant DNA construct.

After induction of expression with IPTG, the bacteria were harvested by centrifugation at 3000 Xg for 20 minutes at 4 ℃ using a Sorvall RC-3B centrifuge. The pellet was resuspended in 50. mu.l of ice-cold 10mM 、pH8.0、0.1M And 0.1mM EDTA (STE buffer). The cells were then centrifuged at 2000 Xg for 20 minutes at 4 ℃. The weight of the precipitate (average wet weight =6 g/l) was weighed and purification of the recombinant protein was performed as follows.

Purification of soluble glutamate racemase

All steps were carried out at 4 ℃. The cells were resuspended in 4 volumes of lysis buffer (50mM potassium phosphate, pH7.0, 100mM potassium phosphate) 2mM EDTA, 2mM EGTA, 10% glycerol, 10mM D, L-glutamic acid, 0.1% β -mercaptoethanol, 200ug/ml lysozyme, 1mM PMSF and each 10ug/ml leupeptin, aprotinin, pepstatin, L-1-chloro-3- [ 4-methylsulfamoyl]-7-amino-2-heptanone (TCLK), L-1-chloro-3- [ 4-methylsulfamide]4-phenyl-2-butanone (TPCK) and soybean trypsin inhibitor) and passed several times through a small volume of a microfluidizer (type M-110S, Mi)crofelicids international Corporation, Newton, MA). The resulting homogenate was diluted with 1 volume of buffer A (10 mM) pH7.0, 0.1mM EGTA, 10% glycerol,1mM D, L-glutamic acid, 1mM PMSF, 0.1% β -mercaptoethanol) and made 0.1% Brij35, centrifuged at 10,000 Xg for 1 hour to yield a clear supernatant (crude extract).

After filtration through a 0.80um filter, the extract was directly applied with a solution containing 100mM And a 20ml Q-Sepharose column pre-equilibrated with buffer A of 0.02% Brij-35. With a medium containing 100mM of And 100 ml (5 bed volumes) of buffer A of 0.02% Brij-35, followed by washing the column with 100 ml Linearly increasing (100-500mM) buffer A was developed. The band corresponding to a molecular weight of 28,000 is the glutamic acid racemase gene product of recombinant helicobacter pylori mur I at about 200-280mM Eluted with a gradient. Each column fraction was individually characterized for glutamate racemase activity (see assay description below), and the protein profile of the fractions was analyzed in a 12% acrylamide SDS-PAGE gel.

The fractions containing glutamate racemase were mixed, brought to 70% saturation with solid ammonium sulfate, stirred at room temperature for 20 minutes, then centrifuged at 27,000 Xg for 20 minutes, and the resulting pellet resuspended in lysis buffer to a final volume of 8ml and applied directly to buffer B (10mM HEPES, pH7.5, 150 mM) 0.1mM EGTA, 10% glycerol, 1mM D, L-glutamic acid, 0.1mM PMSF, 0.1% β -mercaptoethanol) on Sephacryl S-100HR gel filtration matrix (2.2X 92cm) at a flow rate of 30 ml/HR, the fractions containing glutamate racemase activity were mixed, and 0.5 volume of buffer C (10mM Tris pH7.5, 0.1mM EGTA, 10% glycerol, 1mM D, L-glutamic acid, 0.1mM PMSF, 0.1% β -mercaptoethanol) was added (to the mixture) (to make the mixture solid phase react with water to form a solid phase To a concentration of 100mM) and a solution containing 100mM of the above-mentioned compound Buffer C of (2) on a Mono Q10/10 high pressure liquid chromatography column. The column was washed with 5 bed volumes of this buffer and increased with a 40ml linear gradient (100 to 500) performing unfolding. One peak of glutamate racemase at 310mM The fractions containing glutamate racemase activity were combined and pooled with storage buffer (50% glycerol, 10mM 3-N-morpholino-propanesulfonic acid (MOPS) pH7.0, 150 mM) 0.1mM EGTA, 0.02% Brij35, 1mM Dithiothreitol (DTT)) was dialyzed, concentrated, and stored at-20 ℃.

Analysis of glutamate racemase Activity

Conversion of D-glutamic acid to L-glutamic acid (two-enzyme coupling assay)

Glutamate racemase Activity interconversions of glutamate isomers were measured using D-glutamate as a substrate. We adopted Gallo and Knowles (Gallo, K.A. and Knowles, J.R.,1993 biochem 32, 3981-3990) to measure L.fermentumMethod for measuring glutamate racemase Activity the glutamate racemase activity of the H.pylori mur I gene product, which was isolated as a recombinant protein from E.coli, was measured. In this assay, glutamate racemase activity is measured with a series of L-glutamate dehydrogenases (NAD dehydrogenase)⁺Reduction to NADH) and lipoamide dehydrogenase (vat dye to iodonitrotetrazolium violet, INT) activity coupled to OD changes within the visual range. The initial rate was determined by mixing the mixture in a medium containing 50mM pH7.8, 4% v/v glycerol, 10mM NAD, 2mM INF, 60 units/ml L-glutamate dehydrogenase, 5 units/ml lipoamide dehydrogenase and various concentrations of substrate (from 0.063mM to 250mM D-glutamate) or purified enzyme (1ug to 50ug) were measured by increasing the light absorption at 500nm in a 200ul reaction volume without substrate (D-glutamate)) Or all other reagents for the enzyme (mur I gene product) for 5 minutes, the missing component (i.e.the desired enzyme or substrate) is added to start the reaction, the increase in optical density at 500nm is measured using a Microplate spectrophotometer systems (molecular devices, Spectra MAX250) for a total of 20 minutes, and the initial velocity is deduced by calculating the maximum slope of the increase in optical absorption. The coupling reaction can be summarized as follows: 1) d-glutamic acid- - - - - - - - - - - - → L-glutamic acid racemase 2) L-glutamic acid + H₂O+NAD⁺- - - - - - - - - - - - - → 2-oxoglutarate+ NH₃+ NADH L-glutamate dehydrogenase 3) NADH + INF- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -⁺+ methylthio (coloured) octanoyl amide dehydrogenase

Conversion of D-glutamic acid to L-glutamic acid (Single enzyme coupling assay)

In this assay, the conversion of D-glutamic acid to L-glutamic acid is coupled with L-glutamate dehydrogenase to convert L-glutamic acid and NAD⁺Conversion to 2-ketoglutarate coupled with ammonia, the increase in absorbance of the product NADH at 340nm at 37 ℃ (NAD)⁺Reduction to NADH). Standard test mixtures (from Choi, S-Y, Esaki, N., Yoshimura, T., and Soda, K.1991, expression and purification of proteins, Vol.2, pp.90-93) contained 10mM 、pH7.5、5mM NAD⁺5 units/ml of glutamate dehydrogenase, various concentrations of the substrate D-glutamic acid (from 0.063mM to 250mM) or purified recombinant helicobacter pylori glutamate racemase (1ug to 50 ug). After preheating the other assay components at 37 ℃ for 5 minutes, the reaction was initiated by adding the substrate D-glutamic acid or recombinant glutamate racemase. At 340nmThe change in the light absorption value was measured using Spectra MAX250, and the initial velocity was obtained from the initial slope. The coupling reaction can be summarized as follows: 1) d-glutamic acid- - - - - - - - - - - - - - - → L-glutamic acid racemase 2) L-glutamic acid + H₂O+NAD⁺- - - - - - - - - - - - - - - - → 2-oxoglutarate + NH₃+ NADH L-glutamate dehydrogenase

Results

1) Expression of the H.pylori mur I gene in E.coli cells

To examine its biochemical properties, we overexpressed and purified the H.pylori glutamate racemase in E.coli. In the presence of the E.coli chaperones GroES and GroEL, glutamate racemase is expressed as a soluble protein, which yields 20mg of soluble MurI per liter of culture, as judged by the protein band after SDS-PAGE. In the control band generated from cell extracts transformed with the pET vector without the inserted mur I, there was no band corresponding to the molecular weight of the mur I protein. The apparent expression level was increased by about 5-fold by adding 1mM of D, L-glutamic acid during the culture of the expression cells.

2) Purification of recombinant helicobacter pylori mur I protein

MurI was purified by cation exchange chromatography and gel filtration, and the purified protein migrated as a single polypeptide with an apparent molecular weight of 29kDa in SDS-PAGE analysis, which size agreed with the expected 28.858 molecular weight.

3) Kinetic characterization of the recombinant helicobacter pylori mur I enzyme

The kinetic constants of the recombinant glutamate racemase were estimated by analyzing their activities at different concentrations of protein and D-glutamic acid as described above. Purified recombinant helicobacter pylori glutamate racemase exhibiting V_maxAbout 300 nmol/min/mg protein (K)_cat=8.6min^-1) And K to D-glutamic acid_mIs about 100 uM. Albeit V_maxA value lower than that observed for the high-purity glutamic acid racemase of other bacterial species, but which is K for D-glutamic acid_mHigher than that observed for most other species of enzyme, and thus it is capable of producing catalytic efficiencies (K) typical of E.coli and P.pentococcus purified preparations_cat/K_m)。

4) Muri characteristics: inhibited by L-serine-O-sulfuric acid

We examined the inactivation of the helicobacter pylori glutamate racemase by the sucide inhibitor L-serine-O-sulfuric acid, which is known to inhibit MurI of Escherichia coli, and incubated the enzyme in the presence of 20mM L-serine-O-sulfuric acid and at various time intervals, aliquots were taken to measure the residual activity. The initial rate of purified recombinant H.pylori mur I protein in the single enzyme coupling assay was measured after incubation with 20mM of the inhibitor L-serine-O-sulfuric acid (LSOS) and the time was shown as the X-axis, whereas the control was incubated in the same manner in the absence of LSOS, as shown in FIG. 7, where H.pylori glutamate racemase is readily inactivated by the inhibitor.

Future application of glutamate racemase activity in high-throughput drug screening assays

The above-described test for measuring the glutamate racemase activity of H.pylori is performed in a 96-well plate, so that a plurality of reactions can be performed simultaneously, and the measurement of the activity in a multi-well format can be easily amplified, thereby enabling rapid analysis of a large number of compounds inhibiting the glutamate racemase activity. Compounds which inhibit glutamate racemase activity are useful as novel antibiotics and are useful in the treatment and eradication of bacterial (e.g., helicobacter pylori) infections in humans. Known glutamate racemase inhibitors, such as L-serine-O-sulfuric acid, can be used to calibrate high throughput screening of new compound libraries to help identify new compounds with properties suitable for human therapy.

Statement of equivalence

Those of skill in the art will recognize, or be able to ascertain using no more than routine experimentation, many equivalents to the specific embodiments and methods described herein, which are intended to be encompassed by the following claims.

Sequence Listing (1) general information

Applicant (i) has come to

(A) Name: astra Aktiebola

(B) Street: s-15185

(C) City: sodertalje

(D) State:

(E) the state is as follows: sweden

(F) Post code (ZIP)

(ii) title of the invention: nucleic acid and amino acid sequences related to helicobacter pylori and vaccine compositions thereof

(iii) number of sequences: 1298

(iv) communication address:

(A) the contact person: LAHIVE&COCKFIELD

(B) Street: 60 State Street, Suite 510

(C) City: boston

(D) State: massachusetts

(E) The state is as follows: united states of America

(F)ZIP:02109-1875

(v) a computer-readable form:

(A) type of medium: CD/ROM ISO9660

(B) A computer:

(C) operating the system:

(D) software:

(vi) data of the current application:

(A) application No.:

(B) application date:

(vii) prior applications data:

(A) application No.: US 08/625,811

(B) Application date: 3 month 29 1996

(viii) previously applying for data:

(A) application No.: US 08/758,731

(B) Application date: 4.4.2 days in 1996

(ix) prior application data:

(A) application No.: US 08/736,905

(B) Application date: 10 month and 25 days 1996

(x) prior application data:

(A) application No.: US 08/738,859

(B) Application date: 1996, 10 months, 28 days

(xi) prior application data:

(A) application No.: US 08/761,318

(B) Application date: 12 month and 6 days 1996

(xii) attorney/agent information:

(A) name: mandragouras, Amy E

(B) Registration number: 36,207

(C) Document/case No.: GTN-009C2PC

(xiii) telecommunication information:

(A) telephone: (617)227-7400

(B) Faxing: (617)227-5941(2) information of SEQ ID NO:1

Sequence properties:

(A) length: 288 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(vi) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...288

(xi) sequence representation: SEQ ID NO 1: GAGAGGATAA AAAGGAGAGC GGTGATGAAA AAAATCGTTG TGAGTTTATG CGTGGCGTTA 60GGTTTTTTAA GCGCGGATCC AGCGCAGGCC AATAAAGCGA TCAGTGATGC GGATTTGATT 120GAAGAGATAA GGGACTTGAA AAAAATCATC AGCGCACAAA ACACGGAGAT TAACCAATTA 180AGAAAAGTGC AAGAAGTCTT ATCTGGGCAA TTAGGGGACA TGCGTAAGGA TATATTAAGC 240ACTAGAGATT ACTGTATCAG CTTAAGCCCT TATATTTATA ATTGGCGC 288(2) SEQ ID NO 2 information

Sequence properties:

(A) length: 903 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...903

(xi) sequence representation: SEQ ID NO 2: AACGCTTCCA ATGATTTCGT TAAAAGCGGA TCTTTAGGGC CTTTTAGCAA TGGTTATTAT 60GAGCATAAAA CTATTCGTTT AAACCCAGAA CAAAATTTAA TCGTCTTAAG CCACTACCTC 120AAGCTTTTAG AAATCCAAAG GGAAGCGGCG AAAATGACCG CTATTTTTGG GGCCAAACAA 180CCTCACCCAC AAAGCCTAAC GGTGGGGGGT GTTACGAGTG TCATGGATAT ATTGGATCCA 240ACAAGGTTGG CTGAATGGAA GAGCAAGTTT GAAGTGGTGG CTAATTTTAT CAACCATGCT 300TACTACCCTG ATTTGGTGAT GGCAGGCGAA ATGTTCGCTA ACGAACCATC TGTTATTAAA 360GGCTGTGGTT TAAGGAATTT TATCGCTTAT GAAGAAGTGT TGCTTGGGAA GGATAAATAC 420CTTTTGAGTA GTGGGGTGGT GCTTGATGGG GATATTTCTA AATTACACCC CATTGATGAA 480AGTTTGATTA AAGAAGAGGT TACGCATTCT TGGTATCAAT ATGAAGACAC TAAAGAAGTG 540CAACTCCACC CTTATGACGG GCAAACTAAC CCGCATTATA CCGGTTTAAA AGACGGCGAG 600AGCGTGGGGA TTGAAAATAA AATAATCCCT GCTAAAGTGC TTGACACTAA GGATAAATAT 660TCTTGGATAA AATCGCCCAGATACGATAGT AAGCCCATGG AAGTAGGGCC TTTAAGTTCC 720GTAGTGGTAG GTTTAGCGGC GAAAAACCCT TATGTTACTG AAGTGGCTAC TAAATTTTTA 780AAAGACACGA AACTGCCTTT AGAGGCGTTG TTTTCAACGC TTGGGCGCAC ACCTGCAAGG 840TGTATTGAAG CTAAGACTAT CGCTGATAAT GGTCTTTTGG CGTTTGACGC CTTAGTGGAA 900ATC 903(2) SEQ ID NO 3 information

Sequence properties:

(A) length: 507 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...507

(xi) sequence representation: SEQ ID NO 3: GGGATTAACA TGTCAAAAAA AATCGTAGTC GATCCTATCA CTAGGATTGA GGGGCATTTA 60AGGATTGAGG TGATCGTAGA TGATGATAAT GTGATCACCG ATGCGTTTTC TTCTTCTACG 120CTTTTTAGGG GGCTAGAAAC GATCATTAAG GGCAGAGACC CACGAGATGC AGGCTTTATC 180GCTCAAAGGA TTTGTGGGGT ATGCACTTAT TCGCATTATA AAGCCGGTGT TACTGCGGTA 240GAAAACGCTT TAGGAATCAC TCCCCCATTA AACGCGCAAT TGGTGCGATC TTTGATGAAC 300ATGGCGTTGC TTTTTCACGA TCATGTGGTG CATTTCTATA CTTTGCATGG GCTTGATTGG 360TGCGATATTT TGAGCACTTT AAAAGCTGAT CCCATTCAAG CAGCAAAACT TTCTTTCAAA 420TACAGCCCTT ATCCCATTAA TACCGGTGCG GGGCGAATTA AAAGCGGTTC TAAAACGCTT 480GGAATGATTT CGTTAAAAGC GGATCTT 507(2) SEQ ID NO 4 information

Sequence properties:

(A) length: 555 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...555

(xi) sequence representation: SEQ ID NO 4: TGGCTATGGT TACACCAAAG AATGAGTCAA AAAATCCTAA TTTTAGGCAT TGGCAATATC 60CTTTTTGGCG ATGAAGGGAT TGGGGTGCAT CTAGCCCACT ACCTCAAAAG GAATTTTTCT 120TTTTTCCCTA GCGTGGATAT TGTGGATGGG GGGACTATGG CTCAGCAACT CATTCCTTTA 180ATCACTTCGT ATGAAAAGGT TTTGATTTTA GATTGCGTGA GCGCTAAAGG CGTTGAAATT 240GGCTCAGTTT ATGCCTTTGA TTTTAAGGAC GCTCCTAAAG AAATCACATG GGCTGGGAGT 300GCGCATGAAG TGGAAATGCT GCACACTTTA AGGCTCACGG AGTTTTTAGG GGATTTGCCT 360AAAACTTTTA TCGTGGGGCT TGTGCCTTTT GTGATAGGGA GCGAGACCAC TTTCAAGCTT 420TCAAGCGAAA TGTTAAACGC TTTAGAAACA GCCCTAAAAG CCATAGAAAC CCAACTCAAC 480GCATGGGGAG TTAAAATGCA ACGCACCGAT CATATTGCCC TAGATTGTAT CGCTGAACTC 540TCTTATAAGG GTTTT 555(2) SEQ ID NO 5 information

Sequence properties:

(A) length: 324 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...324

(xi) sequence representation: SEQ ID NO 5: TATCAAATCT TAAACCAAAG AAAAACCATG AAAAAAGTCC TCTTACTAAC TCTCTCTCTC 60TCTCTCTCGT TTTGGCTCCA CGCTGAAAGG AACGGATTTT ATTTAGGTTT AAATTTTGCA 120GAAGGAAGCT ATATTCAAGG ACAAGGTAGC ATCGGCGAAA AAGCTTCAGC AGAAAACGCC 180TTAAATCAAG CGATCAATAA CGCACAAAAT TCATTATTCC CTAACACACA AGCCATAAGA 240GATGTGCAAA ACGCCTTAAA TGCAGTGAAA GATTCAAACA AAATCGCTAA CCGATTCGCA 300GGAAATGGTG GATCGGGCGG TATT 324(2) SEQ ID NO 6 information

(ii) sequence properties:

(A) length: 384 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...384

(xi) sequence representation: SEQ ID NO 6: CGCGTTAGTG GAAATCTAAA GAGCGATCAA AGCACTTGTG CTCCTTATCA TATTGATAAA 60AATCAAGAAT ATAAAGGGCG CTACATTGGT CAAGTGCCAA GGGGCATGTT AAGCCATTGG 120GTGCGTATTA AAAACGGCGT GGTGGAAAAT TATCAAGCGG TAGTGCCTTC CACTTGGAAT 180GCAGGGCCTA GAGATTCTAA AAATCAAAGG GGGGCTTATG AAATGAGCTT GATTGGCACT 240AAAATCGCTG ATTTAACCCA GCCTTTAGAA ATCATTAGGA CTATCCATTC TTTTGATCCA 300TGCATCGCAT GCTCAGTGCA TGTGATGGAT TTTAAAGGGC AGTCTTTGAA CGAGTTCAAA 360GTAGAGCCTA ATTTCGCTAA ATTC 384(2) SEQ ID NO 7 information

Sequence properties:

(A) length: 258 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...258

(xi) sequence representation: SEQ ID NO 7: TTATACCAGA ACGACAAGGG TTTTAAAACA GAACTGCGCA TTTTGAGCGT GTTTATCGTG 60GAATTTTTGG TGAATATTCT AGGGTTTATG TTGGCTCATA TGCTTCATTT CTGGTTTTTA 120AGGTGCGTTA AAGCTTTAGC GTGGCTCATG AAAACTTTTG ATAGGCGCCG TTATTTTGAC 180GCTAAGGCCA ATTTGGATTT TGTGTTTGGA GATTCTAAAA GCGAAGAAGA GAAAAAAAGG 240ATCATTAAAA AAGGGGTA 258(2) SEQ ID NO 8 information

(ii) sequence properties:

(A) length: 201 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...201

(xi) sequence representation: SEQ ID NO 8: TACAAAAAAG GAAATCAAAT AATGAATATT CAAACAAAGA AAAGATTTTT AGCAAATTTA 60TTGCTTTTTA GCCTGTTTTC TTGCCTTAAG GCTGAAACCC TTTCAGAAGA CCATCAAATC 120CTGTTGAGTT CAGACGCTTT CCATAGAGGG GATTTTGCCA CCGCTCAAAA AGGCTATATG 180AATCTCTATA GAGCAAACCA A201 (2) SEQ ID NO 9 information

Sequence properties:

(A) length: 768 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...768

(xi) sequence representation: SEQ ID NO 9: TTGTGTTTGA AACTCTTAAT TTGGAATTTT AAGGAGCATT CTTTGAAAGT CAATTTCTTT 60GCCACTTGTC TAGGAGCAGC TATTTATAGC AACGCATCGC TTAACGCTAT CAAATTACTC 120CGCAAGGAAA ATTTGGAAGT GGTTTTTAAA AAAGACCAGA CATGTTGTGG CCAGCCAAGC 180TACAACTCAG GATACTATGA AGAGACTAAA AAAGTCGTTT TATACAATAT CAAACTTTAT 240TCCAATAACG ACTACCCTAT TATTTTGCCT AGCGGTTCAT GCACAGGGAT GATGCGGCAT 300GATTATTTGG AATTGTTTGA AGGGCATGCG GAATTTAACA TGGTTAAAGA TTTTTGCTCT 360AGGGTGTATG AATTGAGCGA GTTTTTGGAT AAAAAATTGC AAGTGAAATA CGAAGATAAG 420GGCGAACCTC TCAAAATCAC ATGGCATTCTAATTGCCATG CC TTAAGGGT GGCTAAAGTG 480ATTGACTCGG CGAAAAATCT CATCAGACAG CTTAAAAATG TGGAACTCAT TGAATTGGAA 540AAAGAAGAAG AATGCTGCGG GTTTGGGGGG ACTTTTTCAG TTAAAGAGCC TGAAATTTCA 600GCGGTTATGG TCAAAGAAAA GATTAAAGAC ATAGAGAGCC GTCATGTGGA TGTGATCGTT 660TCAGCGGATG CTGGGTGCTT GATGAATATC AGCACCGCTA TGCAAAAAAT GGGCTCTTTG 720ACAAAACCCA TGCATTTTTA TGACTTTTTA GCCTCAAGGC TTGGACTT 768(2) SEQ ID NO 10 info 10

Sequence properties:

(A) length: 765 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...765

(xi) sequence representation: SEQ ID NO 10: ATGAAAAAGA TTTTTTTAGG TATGGCATTA GCCTTTAGTC TGTCCATGGC AGAAAAAAGC 60GGCGCGTTTT TAGGAGGGGG GTTTCAATAT TCTAATTTAG AAAACCAAAA CACCACCCGC 120ACCCCAAGCG CTAACAATAA CACCCCGATA AACACTTCAA TGTTTGGCAA CAATCAAGCG 180GCTCCAGCCC AAGAAACGCC AAGCGTGATC AACACCAATA ATTACGGGCA AATGTATGGG 240GTAGATGCGA TGGCAGGGTA TAAGTGGTTC TTTGGCAAAA CCAAACGCTT TGGCTTTAGG 300ACTTATGGAT ACTACAGCTA TAACCATGCG AATTTGAGCT TTGTAGGCAG TAAGCTTGGA 360ATCATGGATG GCGCATCTCA AGTGAATAAC TTCACTTATG GCGTGGGCTT TGATGCGCTC 420TATAACTTCT ATGAAAGCAA AGAGGGCTAT AACACAGCAG GGTTGTTCGT GGGCTTTGGA 480TTAGGAGGGG ATTCGTTTAT CGTTCAAGGA GAGAGCTACT TGAAATCTCA GATGCAAATT 540TGCAACAACA CCGCCGGCTG TTCAGCGAGC ATGAACACGA GCTACTTCCA AATGCCTGTG 600GAATTTGGTT TTAGGAGCAA TTTCTCTAAA CACAGCGGGA TTGAAGTGGG CTTTAAATTG 660CCTTTATTTA CCAACCAATT CTATAAAGAA AGGGGCGTAG ATGGATCGGT AGATGTGTTC 720TATAAAAGGA ATTTCTCTAT CTATTTTAAC TACATGATCA ACCTC 765(2) SEQ ID NO 11 information

(ii) sequence properties:

(A) length: 654 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...654

(xi) sequence representation: SEQ ID NO 11: GCATGTGAAA TTAGAGCATG GGCGTTTGAT AGAATGTTAA GGGTTTTAAG CGTTGGTGTT 60GTTTTTATTT TACTAGGGTG TCAGTTTTTC AACAAAACGA CTCTGCATTT AAAATATAAG 120GATTACCCCA AAAACAGCCC TTTAAAAACC GCTTCCACTT TAACCCCCCC TAAAATCTTT 180TTTAACGCTC ATTTTGTGCC GCCCTTTTAC CAAAAAGAAT TTAAAAAAGC GCTCGCCCAG 240CAAATCGCTT ATTTTTTAAA GGATAAAAGC GCTCTCACTT TCAATATTTC AGGCAATGTT 300TTTTTTTCTT TTGAAGAGAG TCCTAAGGAT TTAAAAGCCA TTTAAAGAAA GCTTAAAAAG 360ACGATTGAGC CTAACACTGA CCCAAAAGCC GTCATGCGTT TTTTAAACCT TCAAGCGAGC 420TTGATTTTAG AATGTGTCCC ACAAACCGCT TGCCCATTTG ACACCCTTTT AATCCCCACC 480GCTCTCAGCG TGCCTATTGA TTACGCCAAT CGTTTGGGCG ATAACCCCTC TCTTTTTCCC 540CAAGAAGATA AATCCTATCA TAACGCTTTA ATCAAAGCCC TTAATAAGGC TTACTATTCT 600CTTATGGACG GTTTAGAAAA GCGTTTGAAC GCTATAGAAA ATGCGGCATG GCTT 654(2) information of SEQ ID NO 12

Sequence properties:

(A) length: 372 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...372

(xi) sequence representation: SEQ ID NO 12: ACGATCCAAG AAAGGCTTTA CCGCCATGAA ATCAGCCGCT TGCAGGTAAA GACTGATGAA 60ACTTTAAAAC TCATTAAAGA AGCCAAAAAG CGTTTGAATT ATAACGATGA TATACGAGAT 120GTTTTGCAAG GGCTTTTGAA TATTGTGCCG GATCTTATCA CCATTAATAG CATTGAAATA 180GACCAACAAA GCGTGGTGGT TAGCGGTAAA ACCCCCTCTA AAGAAGCCTT TTACTTTTTG 240TTTCAAAACA AACTAAACCC CATGTTTGAT TATTCTAGGG CGGAATTTTT CCCTTTAAGC 300GACGGGTGGT TTAATTTTGT CTCCACCAAC TTTTCTAATT CCTTACTGAT AAAAAACCCG 360GAGTCTATTA AA 372(2) SEQ ID NO 13 information

Sequence properties:

(A) length: 1134 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1134

(xi) sequence representation: SEQ ID NO:13: ATCTCTATAG AGCAAACCAA TAAAGTGGTG TATGCTAAAG AGGCGGCCAT TTCAGCGGCG 60AGTTTAGGGG ACATTAAAAC CGCTATGCAT TTAGCCATGC TTTTATCAAA AATCACCAAT 120AATCGTAACG ATGTTTCTAT CAATAAGATT TTAGTGGATG GCTATGCACA AATGGGGCAG 180ATTGATAAGG CGATTGAACT ATTACACAAG ATCCGTAAGG AAGAAAAAAC CATACCCACA 240GACAATGTGT TAGGGACTTT GTATTTGACT CAAAAGCGTT TGGATAAGGC TTTCCCGTTG 300TTGAATAAGT TTTATAACCA AGTGCATGAT GAAGACAGCC TAGAAAAACT CATTACGATC 360TATTTTTTAC AAAACCGCAA AAAAGAGGGT TTGGTTCTGT TGCAATCTCA TATACACAGG 420TATGGTTGCT CAGAGCAATT GTGCCAAAAA GCGCTCAACA CCTTCACGCA ATTTAACGAG 480CTTGATTTGG CTAAAACGAC TTTCGCTCGT TTGTATGAAA AAAACCCTAT TGTTCAAAAC 540GCCCAATTTT ACATAGGGGT ATTAATCTTG TTAAAACAGT TTGATAAGGC CCAGCAAATC 600GCAGAATTAT TCCCCTTTGA CAGGCGTTTG TTGCTAGACT TATACACCGC GCAAAAAAAA 660TTTGATCAAG CTTCCAAACA GGCTTCTTTA ATCTATCAAG AAAGAAAAGA CCCTAAATTC 720TTAGGCTTAG AGGCGATTTA TCATTATGAA AGCTTGAGCG CGAATAAGAA AAAGCTCACC 750AAAGAAGAGA TGTTGCCCAT CATTCAAAAA TTAGAGCAAG CCACCAAAGA GCGTCAAGCA 840TGGCTTGCTA AAACTAAAGA TAAAGAAGAC GCGCAAGACG CTTTCTTTTA TAATTTTTTA 900GGGTATTCCT TAATAGATTA TGACATGGAT GTTAAAAGGG GCATGGATCT TGTGAGGAAA 960GCCTTAGCGT TAGATTCTAA CTCAGTGCTT TATTTGGATT CTTTAGCATG GGGTTATTAC 1020AAATTAGGGA ATTGTTTGGA GGCTAAAAAA ATCTTTTCTA GCATCGCTAA AGAGCTTATC 1080CAAAACGAAC CCGAATTGAA AGAACACAAT AAAATCATTC AAGAATGCAA GAAA 1134(2) SEQ ID NO:14 information.

Sequence properties:

(A) length: 468 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DN = A (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...468

(xi) sequence representation: SEQ ID NO 14: TTTTACACTG GCAAAAAGGG GGCTTGCATG CGTAAGATCT TGTTAATGGG CTTGATTTTA 60CAAGCGCTCT TTGGCGAAGA AACCGCGCAA GAATTGTTGC AATGCTCTGC GATTTTTGAA 120TCTAAAAAAC CCGAATTGAA AGAGGATTTG CGCCAATTGA GTGAAAAAGA GCAGTCTTTG 180AGGATCTTGC AAACCGAAAA CGCCCGCCTT TTAGATGAAA AAAGCGATCT GTTAAACAAG 240AAAGAAAAAG AAATAGACGA AAAACTGAAA AATTTAGCCG CTAAAGAAGA AGCCTTTAAA 300ACCTTACAAA CAGAAGAAAA AAAACGCCTT AAAAATTTGA TAGAAGAAAA TGAAGGCATT 360TTAAGAGAAA TCAAGCAGGC TAAAGACAGC AAGATTGGCG AGACTTATTC TAAAATGAAA 420GATTCTAAAT CGGCTCTGAT TTTAGAAAAT TTACCCACTC AAAACGCT 468(2) SEQ ID NO 15 information

Sequence properties:

(A) length: 423 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...423

(xi) sequence representation: SEQ ID NO 15: AAAAGGCTTT GTGATAGGCT TTGGAGCGGG GGATATTACC TATCAGTTGA GAGGCGAAAT 60GTAATGGGCG TAGCGGTTGT TTTATTTTTA ACGCTAATTT TATTGTTTTT AGTTTTAAGG 120GATTTTGGTT TAGCTAGCCC CAAACAAAAG ATTTTAGCTT TTTTAATCGT AGGGATTATA 180GGAGCGAGCA TCAGCGTTTA TACTTATAAA CAAAACCAAC AAAACCAACA AGAAATCGCT 240TTGCAAAGAG CGTTTTTAAG GGGGGAAACC TTGTTGTGTA AAGGCATCAA AGTCAATAAC 300CAAACCTTTA ATTTAGTGAG CGGGACTTTG AGCTTTTTAG GCAAAAAACA AACCCCTATG 360AAAGATGTTC TTGTGGATTT GGATTCTTGT CAGACGCTTC AAAAAGATCC CTTAATCCAA 420CCT 423(2) SEQ ID NO 16 information

Sequence properties:

(A) length: 303 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: iscc _ feature

(B) Position: 1...303

(xi) sequence representation: SEQ ID NO 16: GCAAAAAATA CTATTTTTAA TAACGCTAAT TTTAACAACA GCACTTCTTT TAATTTCAAT 60AATTCTAGCG CGACCACTTC GTTTGTGGGG GATTTCACTA ACGCTAATTC AAATTTGCAA 120ATCGCTGGGA ACGCTGTTTT TGGGAACTCT ACTAATGGCT CTCAAAATAC CGCTAATTTT 180AATAATACCG GCTCTGTTAA TATTGCAGGG AATGCAACCT TTGATAACGT GGTATTTAAC 240AGCCCTACGA ACACAGGCGT GAAAGGGAAA GTTACTCTCA ATAACATCAC TTTAAAAACT 300TGA 303(2) SEQ ID NO 17 information

Sequence properties:

(A) length: 369 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...369

(xi) sequence representation: SEQ ID NO 17: TGGGCGATGA ATGTTTGGGT GTATAGGCCT TTGTTGGCTT TTATGGATAA CAGACAGGCA 60GAGATAAAGG ACAGCTTGGC TAAAATCAAA ACGGATAACA CCCAAAGCGT GGAGATTGGC 120CATCAAATTG AGACTCTTCT TAAAGAAGCC GCTGAAAAGC GCAGGGAAAT GCTAGCAGAA 180GCGATTCAAA AAGCTACAGA GTCTTATGAC GCTGTGATCA AGCAAAAGGA GAACGAACTC 240AATCAAGAGT TTGAAGCGTT CGCAAAGCAA TTACAAAATG AAAAACAAAT CTTAAAAGAG 300CAATTGCAAG CGCAAATGAC GGTATTTGAA GACGAGTTAA ACAAGCGTGT GGCTATGGGT 360TTAGGGAGT 369(2) information of SEQ ID NO 18

Sequence properties:

(A) length: 309 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ii) feature:

(A) name/keyword: iscc _ feature

(B) Position: 1...309

(xi) sequence representation: SEQ ID NO 18: AAGGGGGGAT TTATATCGGC AAAGAGTTGT TTAAGCATGG CTAGTGGCCT TTTTGAAAAC 60GATGAAATCA AAAACAACAA AGCGCGAGAT TTTTTTTATA GCCATAGCTC CCTTATTGTC 120TTTTTCCTCT TACTGCTTGG GTTTGGGTAT TATTTAGGGA AGTTGCTTTT TGGGGGTTCT 180TCTTTAGAGG TCTATTTGGA TTTAAGAGAC AAGCATGAAC GATTGCAACA AGAAATCACC 240GAATTGCAAA GCAAGAATGT GCGCTTGCAA AAGCGTTTGT TTGAGTTGAG GGAATTACGG 300CCTAGAGAT 309(2) information of SEQ ID NO 19

Sequence properties:

(A) length: 996 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand:is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...996

(xi) sequence representation: SEQ ID NO 19: TTATACTATA ATAGCCAATT AAATTGGGGT TTTACTGATT TGTCTTTGTG CGAGCTTTGG 60CTTAGTTTTG TAAGGAATGA GATGATAAAG AGTTGGACTA AAAAGTGGTT TTTGATTTTA 120TTTTTAATGG CAAGCTGTTT TGGTCATTTG GTGGCTACAA CCGGTGAGAA ATATTTTAAG 180ATGGCTAATC AAGCCCTTAA GAGAGGGGAT TACCATAGAG CGGTGGCTTT TTATAAGAGG 240AGCTGTAATT TGAGGATGGG GGTTGGTTGC ACGAGTTTAG GCTCTATGTA TGAATATGGC 300GATGGCGTGG ATCAGAATAT TTCAAAAGCC GTTTTTTATT ACAGAAGAGG GTGTAATTTG 360AGGAATTATC TCGCTTGCGC GAGTTTAGGC TCTATGTATG AAGATGGCGA TGGCGTGCAA 420AAAGACTTTC CAAAGGCTAT CTATTATTAT AGGAGAGGGT GCCACTTAAA AGGTGGGGTG 480AGCTGCGGTA GTTTGGGTTT TATGTATTTC AATGGTACGG GCGTTAAACA AAATTACGCC 540AAAGCCCTTT CTTTTTCTAA ATACGCTTGC AGTTTGAATT ATGGCATTAG TTGTAACTTT 600GTAGGGTATA TGTATAAGAG CGCCA from GGC GTGGAGAAGG ATTTGAAAAA AGCCCTTGCG 660AATTTTAAAA GAGGGTGCCA TTTAAAAGAC GGGGCGAGCT GTGTGAGCTT GGGATACTTG 720TATGAAGCCG GTATGGATGT CAAACAAAAT GAAGAGCAGG CTTTGAATCT TTATAAAAAG 780GGTTGCTCTT TAAAAGAAGG GAGCGGTTGT CATAATGTGG CGGTGATGTA TTACACGGGT 840AAGGGAGCTC CAAAAGATTT GGAGAAAGCC ACTTCATATT ATAAGAAAGG GTGCGCTTTA 900GGCTTTAGTG GTAGTTGTAA GGTGTTAGAA GTGATTGGCA AGGAGTCTGA TAATTTGCAA 960GATGACGCGC AAAACGACAC GCAAGATAGC GTGCAA 996(2) SEQ ID NO 20 info 20

Sequence properties:

(A) length: 282 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: iscc _ feature

(B) Position: 1...282

(xi) sequence representation: SEQ ID NO 20: ATTAAGGTGA GGAGCGTCAA AAAGACTGAG CGAGGCTTAT TGATTGAGAA ATTCACTTCT 60CAAGGCGAAT TAGTGCCTTT AGAAATTGTG GTAGAAACGA TCCTTTCAGA GATTAAAAGC 120TCTAGTAAAG GGATCATTTT AATTGATGGC TATCCCAGGA GCGTGGAGCA AATGCAAGCT 180TTGGATAAGG AATTGAACGC TCCAAATGAA GTGATTTTAA AAAGCGTGAT TGAAGTAGAA 240GTGAGCGAAA ACACCGCTAA AGAAAGGGTT TTAGGGCAGT TT 282(2) SEQ ID NO 21 information

Sequence properties:

(A) length: 339 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...339

(xi) sequence representation: SEQ ID NO 21: CACTTTGTTT TTAGGGGCGA TTTTTGTTGG GCTTATCGCT ATTACTCCAT AGATAAGGAG 60AGAGAGACTC AGACGCATGA CAGCTCTTAC ATTGTGATAG ACGAATTAGT GGGCATGTGC 120CTTGCGATGG CGATTAACGG ATTATCGTTA GTGGGTGTGA TCTTGAGTTT TATCTTTTTA 180GGATGCTATG ATATTACTAA ACCCTCACTC ATTGGCAAAA TAGACAAAGA AGTTAAAGGG 240GGCTTAGGGG TTGTGGCTGA TGACGCTTTA GCCGGGGTTT TAGCCGGATT GAGCACGTTA 300TTAGCCATCA ATATTTTAGG ATTTTTTAACATTAAGTTT 339(2) SEQ ID NO 22 information

Sequence properties:

(A) length: 237 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...237

(xi) sequence representation: SEQ ID NO 22: ATGTGGCCTG TGGCTCTCAA GCAGCCTAAT AGGGTGTCCC ATCATTTTTA TATCATGGCC 60ATGCTTTTTA TTTTATTTGA TGTAGAAATC GTTTTCATGT TCCCTTGGGC GATTGATTTT 120AAAAAGTTAG GCTTGTTTGG GCTCGTTGAA ATGCTAGGCT TTGTCTTCTT TTTGGCAATC 180GGTTTTATTT ACGCTTTAAA GCGAAACGCT TTGAGCTGGC AAAAATTAGA GGTGAAA 237(2) information SEQ ID NO 23

Sequence properties:

(A) length: 180 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...180

(xi) sequence representation: SEQ ID NO 23: TTTGATTTGG GCGTGCGCAC CAACTTTGCA AAAACCAATT TCAATAAGCA CAGATTAGAC 60CAAGGGATAG AATTTGGGGT GAAAATCCCT GTTATCGCTC ATAAATATTT TGCAACCCAA 120GGCTCAAGCG CGAGCTATAT GAGGAATTTT AGCTTCATAT GTGGGCTATT CAGTCGGTTT 180(2) SEQ ID NO 24 information

Sequence properties:

(A) length: 444 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...444

(xi) sequence representation: SEQ ID NO 24: TTTGGTTCAA GAGCTTTTAG AAGAATTTTT ACAAAGTGGG GCGAAAGAGA TTTTAGAAAA 60GGCGCAGTTG TTTTAATGCG TTTATTGATC GCGCTAGTTT TGTTCTTATG GTGGTTAAAT 120TTAGGCGCTA AAGAAGCGGA TTTCATCTCT GATTGGGAAT ACGGACTGGC CCTTTATAAA 180AACCCTAGGG GTGTTGCGTG CGCCAAATGC CATGGCATTA AAGGCGAACA ACAAGAAATC 240ACCTTTTATT ATGAAAAAGG CGAAAAAAAA ATCCTTTACG CCCCTAAAAT CAACCATTTG 300GATTTTAAAA CCTTTAAAGA CGCCTTGAGT TTGGGTTTTT GTATGATGCC TACATACAAC 360CTGAATTTAG AAGAAATCCA AGCGATTTAC CTTTACATCA CCTCTTTAGG GCATAAAGAC 420GAGCGTAAGG ATCCTTCCAA GCCT 444(2) SEQ ID NO 25 information

Sequence properties:

(A) length: 516 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...516

(xi) sequence representation: SEQ ID NO 25: AAAAATAGGC ATAAACTCTT ATACCTTCTA CTTAAAAACC TTAATTTTTT AAAAACCATT 60TCCACAATTT TTACACAAAA GAGGGTTATC ATTCGTTCGC AACAAGGATT TTCTTGTTAT 120CTTAATTTAA AGGTCAAAAC GATGAAAAAG TTAGCCGCTT TATTTTTAGT AAGCGCGTTG 180GGGGTTATGA GTTTGAACGC ATGGGAGCAA ACCCTAAAAG CTAATGATTT GGAAGTGAAA 240ATCAAATCCG TGGGCAACCC CATTAAAGGC GATAACACTT TTGTGCTTAG CCCCACTTTA 300AAAGGTAAGG CTTTAGAAAA AGCTATCGTT AGGGTGCAGT TTATGAtGCC TGAAATGCCC 360GGCATGCCAG CGATGAAAGA AATGGCGCAA GTGAGTGAAA AAAACGGCCT TTATGAAGCT 420AAAACCAATC TTTCCATGAA CGGGACATGG CAGGTTAGGG TGGATATTAA ATCCAAAGAA 480GGCCAAGTTT ATCGCACTAA AACAAGCCTG GATTTA 516(2) SEQ ID NO 26 information

Sequence properties:

(A) length: 222 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...222

(xi) sequence representation: SEQ ID NO 26: TGCTTATTTG TCCTTACAAA ATCTCAAAGG ATTAGAATGA AACGGCTTTT ATTGTTAGCC 60TTGGCCCTCT TTTTTAGCCT CTCATGCACT AACGCTCAAG AAATTAAAGA AACTCAAGAG 120ACTAAAAAAA CTAAAGAAAC TAAAAGCCAA ACCCGTTTTA ACAtTTCCAC CACTAAGGTC 180ATAGAAAAAG AATTTTCTCA AAGCCGGCGC TATTACGCGC TT 222(2) SEQ ID NO 27 information

Sequence properties:

(A) length: 879 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...879

(xi) sequence representation: SEQ ID NO 27: ATAAAGTTTG CTAAAAAGAT AGTTTTAATT TTAAAAAAAG GTGGTTTTAT GAAAACAAAC 60GGGCTTTTTA AAATGTGGGG GCTATTTTTA GTTTTAATCG CTTTAGTCTT TAACGCATGC 120TCTGATAGCC ATAAAGAAAA GAAGGACGCT TTAGAAGTCA TTAAACAAAG GGGGGTTTTA 180AAGGTGGGGG TTTTTAGCGA TAAGCCTCCT TTTGGCTCTG TGGATTCTAA AGGGAACTAT 240CAAGGCTATG ATGTAGTCAT CGCTAAACGC ATGGCCCTTG ATTTATTGGG CGATGAAAAT 300AAGATTGAGT TTATCCCTGT AGAAGCCTCA GCTAGGGTGG AATTTTTAAA AGCCAATAAA 360GTGGATATTA TCATGGCTAA TTTCACGCGC ACTAAAGAAA GAGAAAAAGT CGTGGATTTC 420GCTAATCCGT ATATGAAAGT CGCTTTGGGG GTGATTTCTA AAGATGGGGT CATTAAAAAT 480ATAGAAGAGC TGAAAGATAA AGAGTTGATC GTGAATAAAG GCACGACAGC GGATTTTTAT 540TTCACTAAAA ATTACCCCAA TATCAAACTT TTGAAATTTG AACAAAACAC AGAGACTTTT 600TTAGCCCTTT TAAACAATAA GGCCATCGCA TTAGCCCATG ATAACACTTT GTTGCTCGCT 660TGGGTGAAAC AACACCCTGA ATTTAAATTA GGCATTACAA GCCTTGGCGA TAAGGATGTG 720ATCGCTCCAG CGATTAAAAA AGGCAACCCT AAGCTTTTAG AGTGGTTGAA TAACGAGATT 780GATTCCCTCA TTTCTAGCGA CTTTTTAAAA GAAGCTTATC AAGAGACTTT AGAGCCTATT 840TATGGCGATG GAATCAAACC GGAAGAAATT ATTTTTGAA 879(2) SEQ ID NO 28 info

Sequence properties:

(A) length: 2028 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2028

(xi) sequence representation: 28: GCTTTTGAAG AATTAGAGCCT TTGAGTTTT TCCTTCAATT CGCCTAAAGG GGCGTGCGAA 60AGTTGTTTGG GTTTAGGGAC AAAATTTAGC TTAGATATTA GTAAGATTTT AGATCCTAAC 120ACGCCTTTAA ATCAAGGAGC GATTAAAGTG ATTTTTGGGT ATAACCGCAG TTATTACGCT 180CAAATGTTTG AAGGCTTTTG CACTTATAAT GGCATTGACA GCGCGCTTTG TTTCAACGAA 240TTGAACAAAG AGCAGCAAGA CGCTCTTTTG TATGGGAATG GCACTGAAAT CAGCTTTCAT 300TTTAAAAACA GCCCCTTGAA ACGCCCCTGG AAAGGCATTA TCCAAATCGC TTATGACATG 360TTTAAAGAGC AAAAGGATTT GAGCGATTAC ATGAGCGAAA AAACCTGTTC TTCGTGTAAT 420GGGCATCGCT TGAAAGCCTC AAGTTTGAGC GTCCAAGTCG CTGGCTTGAA AATGGCGGAT 480TTTTTAACTA AGCCCATTGA AGAAGTCTAT CATTTTTTTA ATGATCCCAC GCATTTTAAC 540TATCTTAACG AGCAAGAAAA AAAGATCGCT GAACCCATTT TAAAAGAGAT TTTAGAAAGG 600GTGTTTTTTT TATACGATGT GGGGCTAGGG TATTTGACTT TGGGGAGGGA TGCGCGAACG 660ATTAGCGGAG GGGAGAGCCA AAGGATACGA ATCGCCAGTC AAATCGGGAG CGGTTTGACA 720GGGGTTTTGT ATGTTTTAGA CGAGCCTAGC ATTGGCTTGC ATGAAAAAGA CACGCTCAAA 780CTCATCAACA CCCTTAGGAA TTTACAAAAA AAGGGGAACA CGCTCATTGT CGTAGAGCAT 840GATAAAGAGA CGATTAAGCA TGCGCATTTT GTTGTGCATA TTGGGCCAAA GGCTGGAAGG 900CATGGGGCTG AAGTGGTTTT TAGCGGGAGC GTAAAAGATT TATTGCAAAA TAACCATTCT 960ACCGCCTTGT ATCTCAACGG CACTAAAAAG ATTGAGCGCC CCAAATTTGA ACCCCCTAAA 1020GAAAAGCATT TTTTAGAAAT TAAAAATGTC AATATCAATA ACATTAAGAA TTTGAGCGTT 1080CAAATCCCCT TAAAACAATT GGTGTGCATT ACGGGGGTGA GCGGGAGCGG TAAAAGCTCG 1140CTGATTTTAC AAACCCTTTT ACCCACCGCT CAAACCCTTT TAAACCATGC TAAAAAAAAT 1200CAAAGCTTGA ATGGGGTGGA GATTGTAGGG TTGGAGTATT TGGATAAAGT GATTTATTTA 1260GATCAAGCCC CCATAGGCAA AACCCCACGA AGCAACCCCG CCACTTACAC GGGAGTGATG 1320GATGAAATCA GGATTTTATT TGCCGAGCAA AAAGAAGCTA AAATTTTAGG CTATAGCACG 1380AGCCGTTTCA GCTTTAATGT TAAAGGAGGG CGGTGTGAGA AATGCCAAGG CGATGGGGAT 1440ATTAAAATAG AAATGCACTT TTTGCCTGAT GTGTTAGTCC AATGCGATAG CTGTAAGGGC 1500GCTAAATACA ACCCCCAAAC TTTAGAAATC AAGGTGAAAG GCAAATCCAT TGCTGATGTG 1560TTGAACATGA GCGTGGAAGA AGCTTATGAA TTTTTTGCTA AATTCCCTAA AATCGCTGTG 1620AAGTTAAAAA CGCTTATAGA TGTGGGCTTA GGCTATATCA CTTTAGGGCA AAACGCTACG 1680ACTTTAAGTG GGGGGGAGGC TCAAAGGATC AAATTGGCTA AAGAATTGAG TAAAAAAGAC 1740ACAGGCAAAA CCCTTTATAT TTTAGATGAC CCTACCACCG GTTTGCATTT TGAAGATGTG 1800AATCACCTTT TACAAGTCTT GCATTCTTTG GTGGCGTTAG GCAATTCCAT GCTAGTGATT 1860GAGCATAATT TAGACATCAT CAAAAACGCT GACTACATTA TAGACATGGG GCCTGATGGG 1920GGGGATAAGG GCGGGAAAGT CATTGCGAGC GGCACGCCTT TAGAAGTGGC GCAAAATTGC 1980GAAAAAACCC AAAGCTATAC GGGAAAATTT TTAGCTTTGG AATTGAAA 2028(2) SEQ ID NO 29 information

Sequence properties:

(A) length: 414 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...414

(xi) sequence representation: SEQ ID NO 29: ATTATTATTG ACTATTCAAG CCAGTATTTT AGCGGGAGGG CTGCGGCGTT CTATCAAGCT 60TTGGATAATT TCATCTCACG ATACGCGCAA CGCTTGATCG TAACCAATTT GAGTCAAGCG 120ATTCGCATTT ATGGCTATGA AGTGGGTGGG ACTTTTAGAT ACAAGGGCGT GAGTTTGAAT 180GTGGGGATCT CGCGCACTTG GCCCACCACT AGGGGGTATT TAATGGCGGA CAGCTATGAG 240CTTGCCGCAA GCACCGGTAA TGTTTTTATC ATTAAATTGG ATTACACCAT TTCCAAAAAC 300AGGGATCAAT CTTGCATGGC TTTAGCCGCT TTGTTACCGG TTTGGATTAT TGCGGGTTTG 360ATATTTACTT GCCTGATTAT GGGACAGCTG AAAAACCCAA AACCCCTACC GATT 414(2) SEQ ID NO 30 information

Sequence properties:

(A) length: 519 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...519

(xi) sequence representation: SEQ ID NO 30: CAAGGAATGG GCTTGAAAAA TCTCTCAACA CTTCTGGTGT TTTTATTCTT TTGTTTGGGG 60TGTGTGAGCA ATTTTAATGA AGACACTTAC ACGCTAGACT TAGTTTTAGA AAAAAAGATC120CAAGCCAGTA GGAAAGGCGA AATCACCCAA GATAATGTGC CTATCATCAC GGCTATCGCT 180ACGCATTTAA ACGATGTGGA TAGCGGCACT TACTACGATC ATGAGTATTT TTTAGTGGAG 240ATTTTCACGC AAAATAACGA CTGGATAGAT GATGGCTATA TTTCTTATGA ACTTTTTGGC 300ACAAAACCTA CAGGATCAGA ACCTTTATGG GTGCGAGAGA TTACAAGAGA TGAATTTGAT 360GGCATTTTAG AAACCACGAA CCGGTGGAGC CGAGCCTTTT TGATCGCTTT TGACAAATTG 420GATTATTTAG CGGTGCAAGA AGCCAAACTA GAGCTTGATG CCTATAGTTT AGGCAAAATT 480GTTTTTAATT TCGCTTACCA AGTCCCCTTA CCTCAATTT 519(2) SEQ ID NO 31 information

Sequence properties:

(A) length: 327 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...327

(xi) sequence representation: SEQ ID NO 31: CAAAAAGAAG TATCTAACTA TGAGGAATCC ATTTTAGTCA ACACTCCTTA TGCAAGGGTT 60AATATTCTCC CGATTGAAAA AAATGAAAGT CCTATTGAAT TACTGGCTCC GGTAGATTTA 120GTTACCGCTT TGAGCGATTT GATGCTAGGA GGTGAGGGGG CGAGCAAGGA AGAAATGGAT 180AATGACGATT TAGACGCTTT TAAAGAAATG GCTTCTAATA TTTTTGGTGC GATCGCTACA 240AGCTTGAAGT CTCAAGAATT GCTCCCTAAA CTCAATTTCA CCACCACGAA CGCTGAAATC 300GCTAAAGAGC TTCCTAAAAA AGAAGAT 327(2) SEQ ID NO 32 information

Sequence properties:

(A) length: 546 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...546

(xi) sequence representation: SEQ ID NO 32: ATTTGTTTAT TAAAGGAAAA AATCATGTCA AATAGCATGT TGGATAAAAA TAAAGCGATT 60CTTACAGGGG GTGGGGCTTT ATTGTTAGGG CTAATCGTGC TTTTTTATTT GGCTTATCGC 120CCTAAGGCTG AAGTGTTGCA AGGGTTTTTA GAGGCTAGGG AATACAGCGT GAGCTCTAAA 180GTCCCTGGCC GCATTGAAAA GGTGTTTGTT AAAAAAGGCG ATCGCATTAA AAAGGGCGAT 240TTAGTTTTTA GCATTTCTAG CCCTGAATTA GAAGCCAAGC TCGCTCAAGC TGAAGCCGGG 300CATAAAGCCG CTAAAGCCGT TAGCGATGAA GTGAAAAGAG GCTCAAGAGA TGAAACGATC 360AATTCTGCGA GGGACGTTTG GCAAGCGGCA AAATCCCAAG CGAATTTGGC TAAAGAGACT 420TATAAGCGCG TTCAAGATTT GTATGACAAT GGCGTGGCGA GTTTGCAAAA GCGCGATGAA 480GCCTATGCGG CTATGAAAGC ACCAAATACA ACGAGAGCGC GGCTTACCAA AAGTATAAAA 540TGGCTT 546(2) SEQ ID NO 33 information

Sequence properties:

(A) length: 444 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...444

(xi) sequence representation: SEQ ID NO 33: ATGGAATTTT TGAGCGGGTA TTTTTTATGG GTTAAAGCTT TCCATGTGAT AGCGGTCATT 60TCGTGGATGG CAGCGTTATT TTATTTGCCA CGCCTTTTTG TCTATCATGC AGAGAACGCG 120CATAAAAAAG AGTTTGTAGG CGTGGTTCAA ATCCAAGAGA AAAAGCTCTA TTCCTTTATC 180GCTTCGCCGG CGATGGGTTT CACGCTTATT ACAGGGATTT TGATGTTGTT GATCGCCCCT 240GAAATGTTTA AAAGCGGGGG TTGGTTGCAT GCTAAATTGG CTTTAGTGGT ATTGCTTTTA 300ATCTATCATT TTTATTGCAA AAAATGCATG CGCGAGCTGG AAAAAGACCC TACAGGGAAA 360AACGCAAGGT TTTATCGTGT GTTTAATGAA ATACCCACGA TTTTAATGAT CCTTATTGTG 420ATCTTAGTGG TTGTCAAGCC TTTT 444(2) SEQ ID NO 34 information

Sequence properties:

(A) length: 873 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...873

(xi) sequence representation: SEQ ID NO 34: GGATTAACCA TTAGACAGGC GTTTAACAAA ACAAGATCCA CGCATTCAAG AACCCTTTTA 60CTAGACATTG ATTGCGTTAT CCCTAATATT GTTAGGCGTT TGCTCTCTAA TAAAACGCTC 120CCTAAAAGAT TCGCCACTTA TAGCTTGCAA GAAGTGGGCG TTATTTTCCT GACCACTCAG 180ATTTTATCTA TCATGCGCAA GACCCGTTGC TCTAAAACGC TTTTTTTTAT CACTAGGGGC 240AGGGAGAGTT TCCGCTACCA GCTGTGCGAT CATTACAAAC AAAAACGCCA CCAATTTGAT 300GAAGATTTTA GATCCCTTTT AAAAGCTCTC AAAATCGCTT TAGTGGAAAA ATACCCCCTA 360AAAAAAGGGG CTAAAATCCA GGGCGAACAT TGTTTTGAAT ATGAAGCCGA TGATATTATC 420TCTTTTTACA AAAAGAAAGA CCCCAACAAT TATGTGATAG CGAGCATGGA TAAGGATATT 480TTGTATTCCA ATAGAGGCTC TCATTTCAAT CTCAAAACGA ACGCTTTTTT TAATGTGAGC 540CAAAAAGAAG CCCATTTTTT TGCTTATTAC CAATGCGTTG TGGGGGATAA AGGGGATAAT 600ATTAAGGGGG TTAAAGGGAT TGGCGGCTTC AACTATAAAG ATTTTTTAAA CGAAGACGCT 660AAAGAGCATG AACTATGGGA GCAGATCATT CAAGCGTTCA AAATTAAAGA AGATTTGAGC 720GATAGCGAAG CCAAAGAAAA GGCTCTATTA AACATGCGTT TAGTCAATAT GCACCAGATG 780ACCCACCATG GCGTGATCAA ACTATGGGAG CCTGAGTTTA AAAAAGCTTT TTTCCCTAAA 840AAACCCCAAA GACCTGATTT TAAAAGAATT TCT 873(2) SEQ ID NO 35 information

Sequence properties:

(A) length: 579 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: iscc _ feature

(B) Position: 1...579

(xi) sequence representation: SEQ ID NO 35: GGCGTTTATC ATAATAAGGA AATCATTGTC GCTTATAGGA AGATTGGCAA GGTGCATTCC 60ACTTTAACCA CAACAAGCAT GATTTTAGCG TTTGGCGTTC AGAAGGTGCT TTTTAGCGGG 120GTGGCTGGAA GCTTAGTTAA AGATTTAAAA ATCAATGATT TGTTAGTGGC TACTCAATTA 180GTCCAGCACG ATGTGGATTT GAGCGCGTTT GATCACCCTT TAGGGTTTAT CCCCGAAAGC 240GCGATTTTTA TTGAAACGAG TGGAAGTTTA AACGCTTTAG CTAAAAAGAT CGCTAATGAG 300CAACATATCG CGCTCAAAGA AGGCGTCATC GCATCAGGCG ATCAGTTTGT GCATAGCAAA 360GAAAGGAAAG AATTTTTAGTTAGCGAGTTT AAAGCGAGCG CGGTGGAAAT GGAGGGGGCG 420AGCGTGGCGT TTGTGTGCCA AAAATTTGGC GTGCCATGCT GCGTGCTAAG GAGCATTAGC 480GATAACGCCG ATGAAAAAGC CGGTATGAGT TTTGATGAAT TTTTAGAAAA AAGCGCTCAC 540ACTTCAGCGA AATTCTTAAA AAGCATGGTG GATGAGCTT 579(2) SEQ ID NO 36 information

Sequence properties:

(A) length: 240 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 240

(xi) sequence representation: SEQ ID NO 36: AAACTCGCCC TTTTCAAACA ACGCCAACTC AAACAAAATA AAAACGCTCA AGCTAATCCT 60AAAAGCCCTT TCATCACCCA TGTGGTCTTG CCTAAAGAAA CCTTATCTTC TATCGCTAAA 120CGCTATCAAG TCAGCATTTC CAGTATCCAA TTAGCCAATA ACCTCAAAGA TTCTAATATC 180TTTATCCACC AGCGCTTAAT CATCCCCACT AACAAAAAAT TACTCGCTAC AAGGGAATTT 240(2) SEQ ID NO 37 information

Sequence properties:

(A) length: 735 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...735

(xi) sequence representation: SEQ ID NO 37: GGTCATAGAA AAAGAATTTT CTCAAAGCCG GCGCTATTAC GCGCTTTAGA GCCTAATGAA 60GCGCTGATTT TTTCTCAAAC CCTGCGTTTT GATGGCTATG TGGAAAAGCT TTATGCGAAT 120AAAACCTATA CCCCCATTAA AAAGGGCGAT AGGCTATTGA GCGTGTATTC CCCTGAATTA 180GCGGGCGTTC AAAGCGAGCT GTTATCGTCA TTGAAATTCA ACCAGCAAGT GGGAGCGATT 240AAAGAAAAAT TAAAACTACT AGGGCTAGAA AACTTTAGCA TTGAAAAAAT CATCAGCAGC 300CATAAAGTCC AAAATGAAAT CACTATTTAC TCTCGTTTCA ACGGCGTTAT TTTTAAAAAA 360AGCCCGGATC TCAATGAGGG GAGTTTCATT AAAAAAGGGC AAGAGCTTTT CAAAATCATA 420GATTTAAGCC GATTGTGGGC GCTTGTTAAA GTCAATCAAG AGGATTTAGA ATTTTTAAAA 480AACACGCATC AAGCGATTTT GTTCGTAGAG GGGGTTAAAG GCAAGCAAGC AATCACGCTT 540GAAAACATCA ACCCCATCAT AAATGCGCAA GATAAAATGC TAGAAGCGCG CTTCAATGTG 600CCTAATCTTA AATTGCTTTA TTACCCTAAC ATGTTCGCTC AAGTAGAAAT CTTTCACAAA 660CCCCAAAAAA TGAAGATCTT GCCTAAAGAA GCGGTTTTGA TTAAGGGGGG GAAAGCTATC 720GTGTTTAAAA AAGAT 735(2) SEQ ID NO 38 information

Sequence properties:

(A) length: 456 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...456

(xi) sequence representation: SEQ ID NO 38: AGTGGAGAAC ACACAATGAA AAAATATATC TTAAATTTAG CGTTAGTGGG CGCGTTGAGC 60GCGTCGTTTT TGATGGCTAA GCCGGCTCAT AATGCGAATA ACTCTACGCA TAACACGAAA 120GAAACGACTG ATGCTTCAGC AGGCGTGTTA GCGACAGTGG ATGGCAGACC CATCACCAAA 180AGCGATTTTG ATATGATTAA GCAACGAAAT CCTAATTTTG ATTTTGACAA GCTTAAAGAG 240AAAGAAAAAG AAGCCTTGAT TGAGCAAGCT ATCCGCACCG CGCTTGTAGA AAATGAGGCT 300AAGGCAGAAA AGCTTAATCA GACTCCAGAA TTTAAAGCGA TGATGGAAGC GGTTAAAAAA 360CAGGCTTTAG TGGAATTTTG GGCTAAAAAA CAGGCTGAAG AAGTGAAAAA AGATCCAAAT 420CCCAGAAAAA GAAATGCAGG ATTTTTACAA CGCCAA 456(2) SEQ ID NO 39 information

Sequence properties:

(A) length: 552 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...552

(xi) sequence representation: SEQ ID NO 39: AGAGCCTTAA AAACGCATGG CGCTCTTGCC TTTGTTCAAG CTTTTTTGGA GTCTTTTAAG 60GGATTTTTAA GCCAAGCGAC CTTAATTAGC GTTTTAATAC CGAGCGTTTT AATCCTTTTT 120TGCGCGATTT TGCTCCTTTT GGCTCTGCTT TTAAGAAACC GCTGGGCTAG TTATATAACA 180ACAGCAGCTT TTTTGGGCGC GTTTTTAAGC ATGCCTTTTG TTTTGAACGT TTTACTCACT 240CAAGCGATTT ACCCCATAGA AACGCGCATC TTGCACGCTA ATCCCTTAAG TTATAGCAAC 300GCCTTTTCTT TGCAAGTGGG AGTCAAAAAC ATTTCCAAAT TCAGTCTAAA CAAATGCGTT 360TTACGTCTAG AAGTCCTTAA AAACCCTCAC AATTTTGTGG AAGAGCGAGC TTTTAAATGG 420TTTGTCAAAA AAAGCTATGA AAAAACCTTT AAAGAAAAGA TTTTGCCTGA AGAATCCAAG 480GTCTTTTCAT TCTTTATTGA CGACTACCCT TATTCAAAAA CGGCCCCTTA TCAAGTTTCT 540TTGTTTTGTT TG 552(2) information SEQ ID NO 40

Sequence properties:

(A) length: 345 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...345

(xi) sequence representation: SEQ ID NO 40: GCCATGAATA TCAAAACCCA TTCTTCAAAT GAAAAAGAAC GCTTTGTACG CATAGAAGAG 60GACGAAAAGA AAGAATTATT CGCCGAAGCT ACAAATGAAA ATCCGCACGG CCTTTCTTTA 120ATGGCTTTAA TAGGGGTGTT GGTTTTTGGG GGTGCGTTTT TAGCCTTATT AGTGCCTAAA 180ATCTATTTAA GCAATAATAT CTATTATATT AGCCGTAAAA TTAATACCCT AGAAGATCAA 240AAACGCCTGC TTTTAGAAGA ACAGCAAATC CTAAAAAACG AATTAGAAAA AGAGCGTTTT 300AAATACTACA TAGAGAATAG TGAAAATATT GGCGATATTG CGTTT 345(2) SEQ ID NO 41 information

Sequence properties:

(A) length: 714 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...714

(xi) sequence representation: SEQ ID NO 41: CTCCTTTTAA TCCACTTTCT TATTTTAAGG AAACTCTTGC AACATAAAAC CATTATGGAT 60AAGATCATTA TTCAAGGGGC TAGGGAAAAC AATCTCAAAA ATATCTTTTT AGAAATCCCT 120AAAAACCAAT TTGTTGTTTT TACCGGATTA AGCGGTTCGG GTAAATCCAC TCTGGCGTTT 180GACACTCTAT ACGCTGAAGG GCAAAGGCGC TATTTAGAGA GTTTGTCTAG TTATGCGAGG 240CAATTTTTAG ACAAAGTGGG TAAGCCTAAT GTGGATAAAA TTGAAGGCCT AACCCCAGCG 300ATCGCTATTG ATCAAAAAAC CACTTCTAAA AACCCTAGAT CCACTGTGGG GACGATCACT 360GAGATTTATG ATTATTTAAG GTTGTTGCTT GCAAGGGTTG GGGAGCAATT TTGCCCCACA 420TGTTTAGAGC CTATTAGTTC TATGAGCGCG AGCGATATCA TTTCTCAAAT CTGTCATTTA 480GAAGAAAATT CTAAAATCAT TATTCTAGCC CCCATTATTA AAGATAAAAA AGGTTCGTTT 540AACGATAAAT TAGAGAGTTT GCGTTTGAAG GGGTATGTGA GGGCTTTTGT TGATGGGGTG 600ATGGTGCGTT TAGATGAACA AATCCATTTG CACAAAACCA AAAAACACAC CATTGAAGCG 660GTGGTGGATA GGGTGGTTAT CAATAGCGAA AATGCTTCAC GGATCGCTAG CGCG 714(2) SEQ ID NO 42 information

Sequence properties:

(A) length: 1083 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1083

(xi) sequence representation: SEQ ID NO 42: CACCAATCTT TTAAAAGAGC GTTTGAACCA AGAAGAAAAG GGCGAGTTTT TAGAATAATG 60GGTTTTGAAA AAAGCATTTT AGACAaTTTG AACGGAGCGC AAAAAATTGC CGCATGCCAC 120ATTCAAGGGC CTTTATTGAT TTTAGCGGGA GCTGGGAGCG GTAAGACTAA GACTTTAACG 180AGCCGTTTAG CGTATTTGAT TGGCGCTTGT GGCGTGCCTA GCGAAAACAC TTTAACGCTC 240ACTTTCACCA ATAAAGCGAG TAAAGAAATG CAAGAAAGGG CTTTGAAATT GTTGAAAAAC 300CAAGCCCTTA TCCCCCCCTT GCTTTGCACT TTCCATCGTT TTGGTTTGCT GTTTTTAAGG 360CAACACATGA ATCTTTTAAA AAGGGCGTGC GATTTTTCGG TGCTAGATAG CGATGAAGTG 420AAAACGCTCT GCAAACAGCT CAAAATTTCA AATTTCAGGG CGAGCATTTC TCAAATCAAA 480AACGGCATGA TGGATTTGAG CGTGCAAGAT AGCGAATGTT ACAAAGCGTA TGAGCTTTAT 540CAAAACGCGC TCAAAAAAGA CAATTTAGTG GATTTTGACG ATTTGCTTTG TTTGAGCCTT 600AAGATTTTAC AAGATAATGA AAAACTCGCC AAAGAGACCA GCGAACGCTA CCATTACATT 660ATGGTAGATG AGTATCAAGA CACGAACGCC CTGCAACTGG AATTTTTAAA ACAATTGAGT 720TTCACGCACC ATAATTTGTG CGTGGTGGGC GATGACGATC AGAGCATTTA TGGGTTTAGG 780GGGGCTGATA TTTCTAACAT TTTAAATTTT TCCAAGCATT TTAAAGGGGC TAAAATAGTG 840AAATTAGAGA CCAACTACCG CTCTAGCGCT GAAATCTTAG CGTGCGCTAA TTCCCTGATC 900AGCCATAACC AACACCGCCA CATTAAAACG CTTCAAAGTT TCAAAGGTTC GCACAAAAGC 960GTGATTTGTA AAGAATACCC CACGCAAAAA GAAGAGAGCC TGGATGTGGC TTATCAGATT 1020CAAAGCCCTT TTAAAGAAGG GCGAGAATTT AGAAAATATC GCTATTTTGT ATCGTTTAAA 1080TGG 1083(2) SEQ ID NO 43 information

Sequence properties:

(A) length: 456 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...456

(xi) sequence representation: SEQ ID NO 43: ATGAGAAAAA CGATTTCAGC GTTGTTTTTA TCAGCGTGTA TAGGGTTATC GTCTGTTCAT 60GCGAGTAACG CTTTGATTTT ACAAACAGAT TTTAGCCTAA AAGATGGGGC CGTCTCGGCG 120ATGAAAGGCG TCGCTTTCAG CGTTGATTCT AATCTTAAAA TCTTTGATTT AACGCACGAA 180ATCCCCCCGT ATAACATTTG GGAAGGCGCT TACCGCTTGT ATCAGACCGC TAGTTATTGG 240CCAAAAGGCT CGGTATTTGTG AGCGTAGTG GATCCGGGCG TAGGCACTAA TCGTAAATCG 300GTGGTATTGA AAACTAAAAA CGGCCAGTAT TTCGTCTCTC CAGATAACGG CACGCTGACT 360TTGGTAGCGC AAACTTTGGG GATTGATAGC CGAGCTGAAA TTGATGAAAA TTCCATCCGT 420CTGAAAGGTT CGAAATTCCT GTCTTCCCGT CCGGTG 456(2) information SEQ ID NO 44

Sequence properties:

(A) length: 729 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...729

(xi) sequence representation: SEQ ID NO 44: GACATCTTTA ATAAGGAAGA GATCATGGCC ATTGATTTAG CAGAAGTTAC AGGAGCTAAA 60GCCGCGCAAG AAAGGAAAAA AGAACAGCCC ACCATCGCTA ACGGGTTGGA TAAAAACGCT 120TTCATGAAAC TCTTTTTAGA GCAATTGAAA AATCAAGACC CCACCGCTCC TATGGAAACG 180GATAAAATCA TCACCCAAAC CGCGCAACTC ACGCAAGTGG AAATGCAAGA AGAAAACAAA 240AAGACCATGC AAGAAGTCGC CAGTGCGATG AAATCCAATA AAGAAACTAA CGAATCTTTA 300AAAGACTTTC AAGGCGCTTT AAAAGACACC ATGGAAAACC TGAACAAAGG CATGGACGAT 360AGCTTAAAGG CTAACAACGC TTTAAGGGAA GTAAGCGCCC TTAATTCTGT GAGCATGATA 420GGCAAAATCG CTGAAACCGA TGTGAGTGGG GCGAATTTTG ACGGCAACAA CAAGCTTTCT 480TTTTCGCTCT TTTTTGATGA AAAAATTGAC GCTTCTAAAG GAGTGCCAGC GATTCAAATC 540TTAAACGAAA ACAATGAATT GGTCAAAACG ATTCCTTTAA AAGATTATAA CGGGCAAAAG 600GGGTATATCA ATTTTGAATG GGACGGCACA AACGAAAAGG GCGAAAAAGT TCCTAAAGGC 660AATTACAAAA TCAAGGCTGA ATACAATTTA GGCTCTCCAA AGCAAGCTGT ATTTGCAAAC 720GCGCATTGG 729(2) SEQ ID NO 45 information

Sequence properties:

(A) length: 759 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...759

(xi) sequence representation: SEQ ID NO 45: AACGCTCATG CCTTTACCCA TCCATTTAGC GCACCAGCTC GCTTTCGCCT AGCTCAAAAA 60AGAAAAGACA ACACCTTGCC TTTTTTAAGG CCTGATGGCA AGTCTCAAGT GAGCGTGCGT 120TATGAAAACA ACAAGCCTGT AAGCGTTGAT ACGATTGTCA TTTCCACCCA ACATTCCCCA 180GAAGTTTCAC AAAAGCATTT AAAAGAAGCG GTGATTGAAG AGATCGTGTA TAAGGTTTTA 240CCCAAAGAAT ATTTGCATGA CAATATCAAG TTTTTTATAA ACCCTACAGG AAAATTCGTC 300ATCGGTGGGC CTCAAGGCGA TGCGGGTTTG ACAGGTAGAA AAATCATCTG GGATACTTAT 360GGAGGGTTTT GCCCGCATGG AGGGGGAGCG TTTACCGGGA AAGACCCTTA CAAGGTGGAT 420ATGAGCGCGG CTTATGCGGC CCGCTATGTG GCTAAAAATT TGGTAGCGAG CGGGGTTTGC 480GATAAAGCGA CCGTGCAGCT TGCTTATGCG ATTGGGGTGA TAGAGCCTGT GTCTATTTAT 540GTGAACACGC ATAACACGAG CAAGCATTCA AGCGCGGAGT TGGAAAAATG CGTGAAATCG 600GTTTTCAAAC TCACGCCAAA AGGCATCATT GAAAGCTTGG ATTTGTTAAG ACCCATTTAT 660TCGCTCACTT CAGCTTATGG GCATTTTGGG CGCGAGTTAG AAGAATTCAC TTGGGAAAAG 720ACTAACAAGG TTGAAGAGAT TAAAGCGTTC TTTAAGCCT 759(2) SEQ ID NO 46 information

Sequence properties:

(A) length: 195 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...195

(xi) sequence representation: SEQ ID NO 6: GTTATTAGTT ACCATTTTAT TATTCTTAAG GATGTGTTTA TAATGAGAAT TAAGGCTTAT 60TTTTTGCGTT TATCGCACTG GTTTTTATCG TTTGGTTGGG TTTTAGCGCT TGTAAAAACT 120CTCAAAAATC TCAAGATTCT CAAAACAATA CCACCCAACA AGATAGCCCT AAAACCTACA 180CCGTATGGAT CTGAA 195(2) SEQ ID NO 47 information

Sequence properties:

(A) length: 366 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisensestrand: is free of

(v) original source:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...366

(xi) sequence representation: SEQ ID NO 47: AAAGGAATAA GCATGAAAAA ATCCCTTTGT TTGTCTTTCT TTCTGACCTT CTCTAACCCT 60CTTCAAGCCC TTGTCATTGA GCTTTTAGAA GAGATTAAAA CTTCGCCGCA TAAAGGCACT 120TTTAAGGCTA AAGTCCTTGA TTCTAAAGAA CCAAGACAAG TTTTAGCCGT TTATAATATC 180TCCCCACACA AAAAACTCAC GCTCACTATC ACTCACATAT CCACGGCAAT CGTCTATCAA 240CCCCTTGATG AAAAACTTTC TTTAGAAACG ACCTTAAGCC CTAACCGCCC TACTATCCCT 300AGAAACACCC AAATCGTTTT TTCTTCAAAA GAATTGAAAG AACCGCACTC AAACCCAATA 360CCTTCT 366(2) SEQ ID NO 48 information

Sequence properties:

(A) length: 408 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...408

(xi) sequence representation: SEQ ID NO 48: AAAAAATTTC ACACTTTAAT ACTTCCTGTT GACTGGGGAA CTGAGATTGT CTTGGTGGTT 60AGTGGCTCGT TGCAAAACAT TGTTCGTTCT TTTTTGCGAA GGATCAGCGT TTTCTTCATT 120ATTGATTTCA TCAATTTTAT TTTCGTTATT GATCAGATCA TTCACTTCTT TGGTGACTTT 180TTCATCTTCT TCTTCATGCT CAATCTTTTT TATATCCTTA TTAGGTTGATTGATTTCATT 240GTTTTGAGTG GTTTTAGTGT TGTTTTGGTG CGATTGGGAC AATTTTTTAG GCTCATCTTT 300GCGTGCGCTC AACACGCTTT TAACAAGGTA GATATCGATA AAATGAGTGA TTTTAGATTT 360CATCAATTAA GTTTCTTTAA ATCAGTGTAT AATTTGTTTA TTTTATCA 408(2) SEQ ID NO 49 information

Sequence properties:

(A) length: 207 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...207

(xi) sequence representation: SEQ ID NO 49: TACTTCCTGT TGAGTGGGGA ACTGAGATTG TCTTGGTGGT TAGTGGCTCG TTGCAAAACA 60TTGTTCGTTC TTTTTTGCGA AGGATCAGCG TTTTCTTCAT TATTGATTTC ATCAATTTTA 120TTTTCGTTAT TGATCAGATC ATTCACTTCT TTGGTGACTT TTTCATCTTC TTCTTCATGC 180TCAATCTTTT TTATATCCTT ATTAGGT 207(2) SEQ ID NO 50 info

Sequence properties:

(A) length: 729 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: iscc _ feature

(B) Position: 1...729

(xi) sequence representation: SEQ ID NO 50: ACTCTTTTTA AGTCAAGCGA TAAAGTTTGC AACCTAATGA GAGTAATAAT AAAGTTTATG 60CTGATTTCAT TAAAAACATT CCTAAAAATA TTATTGGAAA TATTCCTAAA AACCTTCCAA 120AAGATTTGGA TAGTTTGCGT GGTTATTTGG GGGTTGGGCT GTAGTTTTTT AAACGCTAAC 180AGCGTTCAAT TAGAAGAAAC GCTGAGACGA AATCCTAAAA ATCTTATTTG GCAACACTTT 240AAAAAGAAGT TTAAAAAGAG TAACACGATC CCTTATGCCC CTAATAGCCG TTGGAAATAT 300TTAGGCACAA GTATAGGGAT TTTGGGCGTG TCGTTGGTGA TAGGGATTGT GGGGTTGTAT 30CTCATGCCAG AGAGCGTAaC GAATTGGGAT AAAGAAAAGT TTGGCGTCAA AAGTTGGTTT 420GAAAATGTCC GCATGGGGCC AAAACTAGAC AATGATAGTT TTATTTTTAA TGAAATCTTG 480CACCCTTATT TTGGGGCTAT GTATTACATG CAACCGCGCA TGGCTGGGTT TAGCTGGATG 540ACATCAGCGT TTTTTTCTTT TATCACTTCT ACACTTTTTT GGGAATATGG CTTGGAACCG 600TTTGTGGAAG TGCCTAGCTG GCAGGATTTG GTGATCACGC CCTTACTAGG TTTCATTTTA 660GGGGAAGGGT TTTACCAGCT CACGCCTATA TCCAACGCAA CGAAGGCAAG CTGTTTGGCT 720CTTTATTTT 729(2) SEQ ID NO 51 information

Sequence properties:

(A) length: 1458 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1458

(xi) sequence representation: SEQ ID NO 51: AAAAAAAGGA AACCAATGTT TAGAAAACTA GCAACCTCTG TATCGCTCAT AAGCCTACTA 60ATCTCCAACG CTCTTTATGC TAAAGAAATA AGTGAAGCCG ATAAGGTCAT TAAGGCCACT 120AAAGAAACTA AAGAGACCAA GAAAGAGGCT AAACGCCTCA AAAAAGAAGC TAAACAGCGC 180CAACAGATCC CTGATAATAA GAAACCTCAA TATGTCTCTG TTGATGACAC AAAAACTCAA 240GCGCTTTTTG ATATATATGA CACTTTGAAT GTGAATGACA AAAGCTTTGG GGATTGGTTT 300GGTAATAGCG CTTTGAAAAA CAAAACTTAT CTCTACGCTA TGGATCTATT GGATTATAAC 360AACTACTTAT CCATAGAAAA CCCTATTATC AAAACAAGAG CGATGGGAAC TTATGCAGAT 420CTGATTATCA TCACAGGTTC GTTAGAACAA GTCAATGGGT ATTACAATAT TCTAAAAGCG 480CTCAACAAAC GCAACGCTAA GTTTGTGTTA AAAATCAATG ACAAAATACC TTATGCCCAA 540GCGACTTTTT TGAGAGTGCC AAAAAGAAGC GATCCCAACG CCCACACGCT TGATAAGGGA 600GCGTCAATTG ATGAAAGCAA GCTTTTTGAA CAACAAAAGA AAATGTATTT CAACTACGCC 660AACGATGTGA TCTGCAGACC CAACGATGAA GTGTGTTCGC CCCTAAGAGA TGAAATGGTA 720GCTATGCCCA CTAACGATAG CGTTACTCAA AAACCCAATA TCATTGCTCC TTATAGCCTG 780TATAGACTAA AAGAGACAAA TAACGCCAAT GAAGCCCAAC CATCACCTTA TGCCACTCAA 840ACCGCTCCTG AAAACAGCAA AGAGAAGCTC ATAGAAGAGC TAATCGCCAA CTCCCAACTC 900ATAGCCAATG AAGAAGAGAG GGAAAAGAAA CTCTTAGCAG AAAAAGAAAA ACAAGAGACT 960GAATTGGCTA AATACAAGCT CAAAGATTTA GAAAATCAAA AGAAACTAAA AGCTTTAGAA 1020GCAGAGTTGA AAAAGAAAAA CACTAAGAAA CCTAGAGTAG TGGAAGTGCC TATTCCTCCT 1080AAAACAAGTG ATTCTGATGA AACAATGAGA GTTATCAAAG AAAAAGAAAA CTATAATGGG 1140TTATTACTGG ATAAAGAGAC CACCATCAAA AGAAGCTATA AGGGGACTTT GATCAGTGAA 1200AATTCTTACA GCAAAAAAAC ACCCATCAAC CTTGAGGACT TGAGAAGCTT AGAAGAAGAA 1260ATTAAGAGCT ACTATGTCAA GTCTAATGGC TTGTGTTACG CTAATGGCAT TAACCTCTAT 1320GTAAAAATCA AAAACGATCC CTACAAAGAG GGAATGCTGT GTGGTTATGA GAGCGTTCAA 1380AAACTGCTTT CACCACTAAG GGACAAGCTC AAATACGACA AGCAGAAGTT ACAAAAAGCG 1440TTACTGAAAG ATTTAAAG 1458(2) SEQ ID NO 52 information

Sequence properties:

(A) length: 303 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...303

(xi) sequence representation: SEQ ID NO 52: GTAGTAGGCA CAATGGAAGA CTTTTTGTAT AACACCTTAT ATTTCATAGA GGATTATAAG 60TTGGTTGTTA TTTTTAGTTT CATAGGGTTA ATAGCGTTAT TTTTCCTCTA CAAATTCATA 120AAAACTCAAA AAAAGGTTTT TAAAGATAAA GCTAACCAGC CTCAAAAGAA AAAAAGCTTT 180AAAGAAATCA TTATAGATGG GCTGAAAGAA AGGGTTAAAA CCTTTGGCTT TTGGTTGCCA 240AGCTATACTA TTACTATCCT ATTCTTTTAT CACATCAGGG TTATTTTTCT TGATTCTCTT 300AGG 303(2) SEQ ID NO 53 information

Sequence properties:

(A) length: 879 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...879

(xi) sequence representation: SEQ ID NO 53: AGAATGGCTC AAATTGTAAA AGGATCTGAC ATGTTTGAAG ATTTTTATCG CACTACCCTC 60TCTTTTTTAA GGTCTTTATT GCTTTTATTG GGTTTATTGT TGCCGTTTTC GCTTTGTATA 120GCTGATGAAT ATATTAGCAT AAGTGATGAT TGGGATGAAA GGGCGCGAAA TCAGTGGGAT 180GAAACTGCGC GAAATCATAA GACATATTAT TTTGAAAATG GTTTAGACCA TTTTAATCAA 240GGCCAATACA AGCAAGCCTT TAAAGATTTT AAATTGGCGC AAGAATACAG CATCGGGCTT 300GGCAACGTTT ATTTAGCCAA AATGTATTTG GAGGGAAAGG GCGTGAAAGT GGATTACAAA 360AAAGCGCAAT TCTATGCACA AAACGCTATC AAAGGGTATG GGAGCGGGTT GTTAGGGGGC 420GCTCTTATTT TAGGACGCAT GCAAGCAGAA GGCTTAGGGA TGAAAAAGGA TTTGAAACAA 480GCACTCAAGA CTTACAGGCA TGTGGTTCGC ATGTTTTCTA ATAAAAGTGC AAATTTTGCT 540AACAAATTTG GATCAAACCT TGCGGAATTT ACTAGTATGC TTATTGGATC GCGATTCATT 600GATCTTTCAG GTTTGAGCGC GAATCCTATA AAATTTGGAA ATAAATTTGG AATACTTGTT 660AAGAAAGCCC TTCAAATCAA AGATAATACA CTTTCTTGGG AAGACATTGC TGAAATTTCA 720AGCAATATTA TTTTACTCAA ACAACAAATG GGGGAAATCC TTTATAGGAT TGGGATCGCT 780TATAAAGAAG GGCTTGGCAC TAGAAAGAAA AAGGACAGGG CTAAAAAATT CTTGCAAAAA 840TCCGCAGAAT TTGGCTATGA AAAAGCCATG GAAGCTCTG 879(2) SEQ ID NO 54 information

Sequence properties:

(A) length: 243 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...243

(xi) sequence representation: SEQ ID NO 54: GACTTTCACG ATTTCTGTGC GAATATCCAT CATCGTATCC GTTGGAGGCA CAGGCATATA 60GCCTCCTTGC TTTCCCGGTC TATGCCCAAA ATTCACGCCG TTTTCAAAGC TTTTATCCCT 120ATTCCATTCG CCCTCTTCGC TATCCACTTC GTAGTATTGG GAATTGGAAG CGTCTTTAAT 180CTTAATAGAA TCAAAGATAA AAAATTCATT CTCCGCGCCA AAATAAGCCA CATCGCCCAA 240GCC 243(2) SEQ ID NO 55 information

Sequence properties:

(A) length: 312 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...312

(xi) sequence representation: SEQ ID NO 55: AAAGCCATGC TTTCTTCTAC GAATGACATA CGGTATCAAA ACCCTAAAAA CAAGGCTTTG 60AAAGGCGAAA TATTAGCGAA TCTGAAATTC ATAAAAAAAC TGCTTGGTAT TGGGTGTAAA 120GACCCTAGCG CGTATGTCCA ATTAGGCGTG AGCAAGAGCG AAAAACAAGA AATTGAAAAC 180AAGATAGAAG AAAGAAAACG TGCCAAAGAA CAAAAAGATT TTTTAAAAGC CGATAGCATC 240AGAGAAGAGC TTTTACAACA AAAAATCGCT TTGATGGACA CCCCACAAGG CACGATTTGG 300GAGAAGCTTT TT 312(2) SEQ ID NO 56 information

Sequence properties:

(A) length: 1587 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1587

(xi) sequence representation: SEQ ID NO 56: ATGAGAAAGG TTATCATAAT GAATGGTTAT TTGAGGGTAA AAACCCCGTA TTTTTTAGCG 60TCGGTCGTTT TGACTTTTTG GACTTTTAAT TCTTTTATGA GCGCGAAAGA TAAGCACCAT 120TTTTTAAAAA AAGTTACAAC CACCGAGCAA AAATTCAGTT CTAGTGCCCC AATTTCATGG 180CAAAGCGAAG AGGTGCGTAA TTCCACAAGC TCTCGCACGG TGATTTCCAA CAAAGAACTC 240AAAAAAACGG GGAATTTGAA TATTGAAAAC GCCTTGCAAA ATGTACCAGG GATTCAAATC 300AGAGACGCTA CAGGCACGGG CGTGCTGCCT AAAATTTCGG TGCGCGGTTT TGGTGGGGGC 360GGTAACGGGC ATAGCAACAC CAACATGATT TTAGTCAATG GTATCCCCAT TTATGGCGCG 420CCGTATTCCA ATATTGAACT GGCGATTTTC CCTGTAACTT TCCAGTCAGT GGATAGGATT 480GATGTGATTA AGGGGGGAAC GACCGTCCAA TACGGCCCTA ACACTTTTGG AGGCGTGGTG 540AATGTCATCA CTAAAGAAAT CCCCAAAGAG TGGGAAAATC AAGCGGCTGA AAGGATCACT 600TTTTGGGGGC GCTCCTCTAA TGGGAATTTT GTCGATCCCA AAGAAAAAGG CAAGCCCTTA 660GCCCAAACTT TAGGAAACCA AATGCTGTTT AACACTTATG GGCGAACGGC TGGGATGTTG 720GGTAAATATA TAGGCATTAG CGCTCAAGGC AATTGGATTA ATGGGCAAGG TTTCAGGCAA 780AATAGCCCTA CAAAGGTGCA AAACTACTTG TTGGATGCGA TTTATAAGAT CAATGCGACC 840AATACTTTTA AAGCTTATTA CCAGTATTAT CAATACAACT CTTACCATCC AGGCACTTTG 900AGCGCGCAAG ATTACGCCTA TAACCGCTTC ATCAATGAGC GCCCTGACAA TCAAGATGGA 960GGGCGAGCCA AGCGCTTTGG GATCGTGTAT CAAAACTACT TTGGCGATCC GGATAGGAAA 1020GTGGGGGGCG ATTTTAAATT CACTTATTTC ACGCATGACA TGAGTAGGGA TTTTGGGTTT 1080TCCAACCAAT ACCAAAGCGT GTATATGAGC GGTCAAAATA AGATTTTACC CTTTAAAGGC 1140AAGGGAGAAA TCAGCGCAAA AAACCCTAAT TGCGGTCTGT ATTCTTATAG CGACACGAAT 1200AGCCCTTGCT GGCAATTTTT TGACAATATC CGCCGATCCG TGGTGAATGC CTTTGAGCCA 2260AAACTCAATC TTATCGTCAA TACTGGTAAA GTCAAACAAA CTTTTAACAT GGGAATGCGC 1320TTTTTAACTG AACATTTATA CCGCCGATCC ACCACCAGGA AAAACCCTAG CATGCCTAAT 1380AATGGGAGTG GGTTTGATGC AGGAACTTCA CTCAATAATT TCAACAATTA TACCGCTGTG 1440TATGCCAGCG ATGAAATCAA TTTCAATAAC GGCATGCTAA CGATCACGCC GGGCTTGAGA 1500TACACTTTTT TAAATTACGA AAAAAAAGAC GCTCCTCCCT TTAAGGTGGG TCAAACCCCA 1560AAAACCACGA AAGAGCGTTA TAACCAA 1587(2) information of SEQ ID NO 57

Sequence properties:

(A) length: 582 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...582

(xi) sequence representation: SEQ ID NO 57: CGGGTTGGAT TTCGCTCCTT TAGTGGTGGT CATTGTGCTG AAATTTTTAG ATTTAACCCT 60CATCCAATGG CTTTTTGCGC TCGCCAAAAG CCTCTAAAGG AAATCATGCG TTTTTTTATT 120TTATTTTTTA TGGGTATGCT TGGCGTTGGT TTTTCTCAAA CCGAGTTGGA TTTAAAGGAT 180TTAGAAAAAA AGCCCGCCGG GATCGTTAGG GATTATTATT TATGGCGTTA TATTAGCGAT 240AAAAAAACGA GTTTAGAAAA CGCTAAAAAA GCCTATGAAT TGACTCAAAA TAAAAACAGC 300GCCCTACAAA AAGCCATGCA AGAAAAAGGC GTAGAAAATT CAGATAAAAG CCCTGATGCC 360AAAATGCCTG AAGATATTTA TTGCAAGCAA ATTACCTTAG AAAGCATGTT AGAAACAACA 420GACGCTTTCC AAGCGAGTTG TATCGCTATC GCTTTAAAAT CAAAAATCAG AGATTTTGAT 480AAAATCCCCA TTCAAACCTT TAAACCTTTA CAAGAAAAAA TCAAAGAGGC TTACCCCATT 540CTTTATGAAG AATTAGAAAT CTTGCAAAGT AAGAACGTGA GC 582(2) SEQ ID NO 58 information

Sequence properties:

(A) length: 618 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...618

(xi) sequence representation: SEQ ID NO 58: CACGCCTTGT ATTCGCCCAT CAAAATCGCT TTTGAAAAAG CCCTTAAAAA CGCTAAAGAA 60TCCGTTTTTA TCGCTTCATC GTATTTTATT CCAGGTAAAA AGATAATGAA AATCTTTAAA 120AATCAAATTT CTAAGGGGAT TGAATTGAAT ATTCTTACCA ATTCCCTTTC ATCTACGGAC 180GCTATCGTGG TCTATGGGGC GTGGGAAAGG TATCGCAATA AATTAGTGCG AATGGGCGCG 240AATGTCTATG AAATACGAAA CGATTTTTTC AACCGCCAGA TTAAAGGGCG CTTTAGCACC 300AAACATTCCT TACACGGCAA GACAATTGTT TTTGACGATG CCCTAACGCT TCTAGGGAGT 360TTTAATATTG ATCCGCGCTC TGCATATATT AACACTGAAA GTGCGGTCTT GTTTGACAAC 420CCGTCTTTTG CCAAAAGGGT GCGTTTGTCG CTTAAAGATC ATGCCCAACA ATCATGGCAT 480TTAGTCTTGT ATCGGCATAG AGTGATTTGG GAAGCTACAG AAGAAGGCAT CTTAATCCAT 540GAAAAAAACT CGCCTGATAC CTCTTTCTTT TTGCGTTTGA TTAAAGAATG GTCTAAAGTC 600CTTCCTGAAA GAGAACTT 618(2) information SEQ ID NO 59

Sequence properties:

(A) length: 1326 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(vi) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1326

(xi) sequence representation: SEQ ID NO 59: GGAAAAATTA AAGGTGTGAT GATGAAATTT TTTCTTTTAA AGAAATTCAG CGAATTTTTA 60AACACTCAAA CGCATTTTAA CCTCAAACGC TTGAACGCGT CTAGTTTTTT ATTAGAGACT 120TTTTCTAAAG AAAAACACGC CTTTGTTGTG GATTTGAGCG CGCCTTATAT TGGTTTGTCC 180AAAAAACCCC CAGAGAGCGT TTTAAAAAAC ACTTTAGCGT TAGATTTTTG TTTGAATAAA 240TTCACCAAAA ACGCCAAAAT TTTACAAGCA AACGTCATTG ATAACGATCG GATTTTAGAA 300ATCAAGGGCG CTAAAGATTT AGCTTATAAG AGTGAAACTT TTATTTTGCG TTTAGAAATG 360ATCCCTAAAA AAGCCAATCT CATGATTTTA GATCAAGAAA AATGCGTGAT AGAGGCTTTT 420CGTTTTAATG ACAGGGTGGC TAAAAACGAT ATTTTAGGGG CATTGCCTCC TAATATTTAC 480GAGCATCAAG AAGAGGATTT GGATTTTAAG GGATTGTTGG ACATTTTAGA AAAAGATTTT 540TTATCCTATC AGCACAAAGA ATTGGAACAC AAAAAAAATC AAATCATCAA GCGATTAAAC 600GCCCAAAAAG AACGCTTGAA AGAAAAATTA GAAAAACTAG AAGATCCTAA AACTTTACAG 660CTGGAAGCGA AAGAATTGCA AACTCAAGCC TCATTGTTGC TCACTTACCA GCATTTAATC 720AACAGGCGTG AAAATCGCGT GATTTTAAAG GATTTTGAAG ATAAAGAATG CATGATTGAA 780ATTGATAAGA GCATGCCCTT AAACGCTTTT ATCAATAAAA AATTCACTCT CAGCAAGAAA 840AAGAAACAAA AATCGCAATT CTTGTATTTA GAAGAAGAGA ATCTGAAAGA AAAAATCGCT 900TTTAAGGAAA ATCAAATCAA CTATGTTAGA GACGCTGCAG AAGAAAGCGT TTTAGAAATG 960TTTATGCCGG TAAAAAACTC TAAAATCAAA CGCCCGATGA ACGGGTATGA AGTGCTGTAT 1020TATAAGGATT TTAAAATCGG TTTAGGGAAA AACCAAAAAG AGAATATCAA GCTTTTACAA 1080GACGCAAGAG CGAATGATTT GTGGATGCAT GTGAGAGATA TTCCTGGATC GCATTTGATC 1140GTTTTTTGCC AAAAGAATAC GCCTAAAGAT GAGGTCATTA TGGAATTAGC CAAAATGTTG 1200ATTAAAATGC AAAAAGATGC GTTTAATGGT TACGAGATTG ACTACACGCA ACGAAAATTT 1260GTCAAAATCA TCAAAGGAGC TCATGTCATT TACTCAAAAT ACCGAACTAT TAGTCTAAAG 1320GACACT 1326(2) SEQ ID NO 60 information

Sequence properties:

(A) length: 879 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...879

(xi) sequence representation: SEQ ID NO 60: GGATTTATGA TGATTTTCAT TGACGCATGT TTTAGAAAGG AAACGCCTTA CACACCCATT 60TGGATGATGA GGCAAGCGGG GCGTTACCTT AGCGAATACC AAGAGAGCCG TAAAAAAGCG 120GGGAGCCTCT TGGAATTGTG TAAAAATAGC GATTTAGCCA CAGAAGTTAC CCTACAGCCG 180GTAGAGATTT TAGGCGTGGA TGCGGCTATT TTGTTTAGCG ATATTTTAGT AGTGCCTTTG 240GAAATGGGCT TGAATTTGGA GTTTATCCCC AAAAAGGGGC CGCATTTTTT AGAGACGATT 300ACGGATTTAA AAAGCGTGGA AAGCCTAAAA GTAGGGGTTT ATAAACAACT AAACTATGTC 360TATGATACGA TTTCTCAAAC GCGCCAAAAG CTTTCTAAAG AGAAAGCGCT AATCGGTTTT 420TGCGGATCGC CTTGGACTTT AGCGACTTAC ATGATAGAAG GCGAGGGGAG CAAATCGTAT 480GCCAAAAGCA AGAAAATGCT TTATAGCGAG CCTGAAGTTT TAAAAGCGCT TTTAGAAAAG 540TTAAGCCTTG AATTGATAGA GTATTTGAGC CTTCAAATCC AAGCAGGGGT CAATGCAGTG 600ATGATCTTTG ACTCATGGGC TAGCGCTTTA GAAAAAGAAG CGTATTTGGA ATTCAGTTGG 660GATTATTTGA AAAAAATCTC TAAAGAGCTT AAAAAACGCT ATGCGCACAT CCCAGTTATC 720CTTTTCCCTA AAGGGATTGG CGCTTATTTG GATAGCATAG ATGGGGAATT TGATTTGTTT 780GGCTTGGATG GGGGCACGCC TTTAACTGCG GCAAAAAAAA AATTAGCGGT AATTATTTTT 840TTGCAAGGAA TTTACAACCC ACCCGCCTTT ATGATAAAA 879(2) SEQ ID NO 61 information

Sequence properties:

(A) length: 576 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...576

(xi) sequence representation: SEQ ID NO 61: AGGGTGTTTT TGACTAAAAA ATTCATGTCT TGGATGGTGG TTATCGGGGC TTTAATTTGC 60GTGCTTTTAG GGGTGTTTAT CTTCTTCACT AGCATGTCGG TTAAAAAATC TTTAACCGCT 120TATCTTAACG CTTATTTAGA GCAACGCCCA AATATCGAGG GCATGGGGAT TATAGGAGTT 180CCTTTTAAAT GCGAAAGGTT TTTTAAAATC GCATGCGTTT CTAAAGAACT TCGTTTTTTA 240AATCCTCAAA ACTCTCCTAT TATGGATTTT AAAAATTTAG AGATCAAGCT CCATTCTTTA 300GATAAAAGCT CTCTTACCCT TTCTATCCAT TCTCAAATCC AATCCCCTAT TTTAGAACAA 360TCCATTCAGC AAAAAATCAG CCAAaTCCCC TTAAAAAACT TGAATGCCTT ATTGGAAAAA 420TTCAAACCCA CGCGCTTGAA TTGCTCTTTA ACATTCAACG CTTTAGATGA AAAAACCTTA 480AACGATAATT TAAAATGCGA TTTGACTAAT GCAGAGAATC TCCTGCTACA CTTTTTTTCA 540AGAGGGTTTA ATGGAGGCGC AAGAAAATCT CTCCCT 576(2) SEQ ID NO 62 information

Sequence properties:

(A) length: 1110 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1110

(xi) sequence representation: SEQ ID NO:62: CAGGATCAAC CCATGCAATT TCAAAAAACC TTACTTTCTT TATCTTTATT ATTTTTATCT 60TATTGTATCG CTGAAGAAAA TGGGGCGTAT GCGAGCGTGG GTTTTGAATA TTCCATCAGT 120CATGCCGTTG AACACAATAA CCCTTTTTTG AATCAAGAAC GCATCCAAAC GATTTCTAAC 180GCTCAAAACA AAATCTATAA ACTCAATCAA GTCAAAAATG AAATCACAAA CATGCCCAAC 240ACCTTTAACT ACATCAACAA CGCTTTAAAA AACAATGCTA AATTAACCCC TACTGAAAAG 300CAAGCCGAAA CCTACTACCT GCAATCTACC CTTCAAAACA TTGAAAAAAT AGTCATGCTT 360AGCGGGGGCG TTGCGTCTAA CCCTAAATTA GCCCAAGCGT TAGAAAAAAT GCAAGAACCC 420ATTACTAACC CTTTAGAATT GGTAGAAAAC TTAAAAAATT TAGAATTACA ATTCAGCCAA 480TCTCAAAACA GCATGCTTTC TTCTTTGTCT TCTCAGATCG CTCAAATTTC AAATTCTTTG 540AACGCGCTTG ATCCCAGCTC TTATTCTAAA AACGTTTCAA GCATGTATGG GGTAGGTTTG 600AGCGTAGGGT ATAAGCATTT CTTTACCAAG AAAAAAAATC AAGGGTTTCG TTATTACTTA 660TTCTATGACT ATGGTTACAC TAATTTTGGT TTTGTGGGTA ATGGCTTTGA TGGTTTAGGC 720AAAATGAATA ACCACCTCTA TGGGCTTGGC ATAGATTATC TTTTCAATTT CATTGATAAT 780GCGCAAAAAC ATTCGAGCGT GGGGTTTTAT GTAGGCTTTG CTTTAGCGGG GAGTTCGTGG 840GTAGGGAGTG GTTTAGGCAT GTGGGTGAGT CAAaTGGATT TCATCAACAA CTATTTGACG 900GATTATCGGG CTAAAATGCA CACGAGTTTT TTCCAAATCC CTTTGAATTT TGGGGTTCGT 960GTGAATGTGG ATAGGCACAA TGGTTTTGAA ATGGGCTTAA AGATCCCTTT AGCGGTCAAT 1020TCCTTTTATG AAACGCATGG CAAGGGGTTA AACGCTTCCC TCTTTTTCAA ACGCCTTGTC 1080ATGTTTAACG TGAGTTATGT TTATAGTTTT 1110(2) SEQ ID NO:63 information.

Sequence properties:

(A) length: 729 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...729

(xi) sequence representation: SEQ ID NO 63: GAACCCATGC CTATGGGCAA AGCGCTCAAA GAATACCAGA TCAAAAAAAC CAGAGATGTG 60GGCATTGGCG CTAAAAACAG CGAAATCATG ACCTCCGCTC AAGTGGAATT AGGCAAAATG 120CTCTATTTTG ACCCTAGGAT TTCCACTTCC TATCTTGTGT CTTGCAACAC ATGCCATAAT 180TTGGGCTTAG GCGGGGTGGA TCTAATCCCA AGCGCTATAG GCTCTCAATG GAAGAAAAAC 240CCCCACCTTT TAAGTTCCCC AACGGTGTAT AACTCTGTGT TTAACGATGT GCAGTTTTGG 300GATGGTAGGG TTACGCATTT AAACGAACAA GCGCAAGGGC CAATCCAATC TTCTTTTGAA 360ATGGGGGCTG ATCCTAAAGT CGTGGTAGAA AAAATCAATT CCATACCAGG CTATGTCAAG 420CTCTTTAGAA AAGCTTATGG CTCTAAAGTC AAAATTGATT TTAAATTGAT CGCTGATAGT 480ATCGCTATGT TTGAAGCCAC GCTCATTACC CCAAGCCGTT ACGATGATTT TTTAAGGGGC 540AATCCTAAAG CGCTCAGTAA AGCCGAAAAA GAAGGGCTGG ATTTATTCAT TTCTAAAGGC 600TGTGTGGCGT GTCATAATGG CATCAATCTT GGGGGGACGA TGCAGCCTTT TGGGGTGGTC 660AAACCTTATA AATTCGCTAA TGTGGGCGAT TTCAAGGGCG ATAAAAACGG GCTTGTGAAA 720(2) SEQ ID NO 64 information

Sequence properties:

(A) length: 702 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...702

(xi) sequence representation: SEQ ID NO 64: AACGATTTTT GGAGAAAGGA AATAACCATG AGAGCTACGG CGATAAAAAT CTTTTCATTC 60TCATCAGCGC TCGCCCTATT GCTTCAGGGT TGCTTGAGCA TTAATTTAAA ACAAATGCTG 120CCAGAAATCA GAACTTATGA TTTAAATGCG AGTTCTTTTG AAATGACGCA ATGCCCTAAA 180CCTTTGACTG AAGTGAGGCT CATTATCATT TTGAGCGCGG ATTTATTCAA CACTAAAGAG 240ATCGTGTTTA AAGCGCAAGA CGGGCAGATT ACGCATGGGA AGCACCAAAA ATGGATAGAC 300TTGCCTCGCA ACATGTTAAA AACCATGTTC ATGCAAGAAG CGCAAAAAGC ATGCTTAGGC 360GTGGCTTTGC CCCCTTATGG CGCGGGCGCG CCCACTTATG CGGTTCGTTT TACGATTTTA 420TCGTTTTCTC TTTTAGAAAA AGAAAATTCT ACTTACAGGG CGGAATTCGC GCTAGGCTAT 480GATATTAGCG TGAAAGGCGA TTCGCATTCT GGAGTGATCA TTAAGCATGA AAATATTTCT 540AGCTTGGAAA ATAAAACGAC CAAAACGAGT AAAAATGGCA GTCAAGATTT CCAAGAAAGC 600GCGATACAAT CCcTCCAACA TGTCAGCACG CAAGCGATGC AAGAAGCGAT TTCTTTGATT 660AAAAAGCGG TTGAAGCGCA AAGCGTAAGC CCGTTAAAAA AA 702(2) SEQ ID NO 65 information

Sequence properties:

(A) length: 849 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...849

(xi) sequence representation: SEQ ID NO 65: AGGCAATTTA TTCAATTCAA CACGAGGAGA GAAATTTTGG AAAGGCATGT GAATTACACT 60TTAATCGGCG GGCTCTTCTT TTTATGCTTA GTGTGCATGG TAGGCTTTAT TTTATGGCTA 120GGCCATTTGG GATTAGATGA TGGGAAGTAT TATGAATATG TGGTCTATAC GGACAAAGAC 180TTGGGAGGCA TTGCGACCAA CTCGCCCATT AATTACAAAG GGATTCAAGT GGGTAATGTC 240ATCAAAGTGG GTTTTGCAAA GGATAAAGTG GGGGTGGTCC GTTTGGATTT GATGATCAAA 300TCCAGCGTTA AGATCCGTAA AGATTCCAAA GTGGCGGTTT CTTCTAGAGG GTTTATGGGG 360TTAAAATTTT TAGCCTTAGA GCAAAGCCAC AATGAAGAAT TTTATGGTAG CGGCGATAAA 420GGGGAGCGGA TTTTAATCTT TAAAGAAGGG CTTATGGATC GCTTGAGCGG TGATGCTAAT 480CAAGTGGTGC AAGAAGTGAT GAAAGCGATC AGGAATGTGA ATAGGATTTT AGACGATGAA 540AACGTGGAGA AATTCAAGCA CATTCTCGCT TCAGTGGATG ATCTCATCGC TAACTTGGAT 600TCAAGAAAGA CTCAATTTGA TTCCTTGATC AACAACGCTA ACAACCTTGT TTCTAATGTC 660AATAATGTGG CTTTGGATGT GGATAAACGC GTCAAACAGG GGCAATACGA CTTTAAGGCG 720ATGTTCACTC CTTTAATCAT GCAAGCGCAG TTGAGCTTAA GAAACATTGA TAATTTTGTG 780GAAAAAGGCT CTGCTTTGAT AGATAAATTT GACGCTAACC CCTATAAAAC GATTTTTGGA 840GAAAGGAAA 849(2) SEQ ID NO 66 information

Sequence properties:

(A) length: 453 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...453

(xi) sequence representation: SEQ ID NO 66: AGCAGCTCAC AATCTATAGC CTTACTCATT GGCTTGTGGT TTGGGTTTCA AAAACGCATC 60GCTTTGGGGG TGTGGTTTTT CTTTAGCATC TTATTAGGTG AATTCACCTT AAAATCCCTT 120AAGCTTTTAG TGGCGCGCCC ACGGCCTGTA ACCAATGGCG AATTGGTTTT TGCGCATGGC 180TTTAGTTTCC CTAGCGGGCA TGCTTTAGCT TCAGCGCTTT TTTACGGCTC TTTCGCGTTG 240TTGTTATGCT ATTCTAACGC AAACAATCGC ATTAAAACTA TTGGTGCTAT TATTTTACTT 300TTTTGGATTT TTTTAATGGC GTATGATAGG GTTTATTTAG GGGTGCATTA CCCTAGCGAT 360GTTTTAGGAG GGTTTTTATT AGGGATTGCT TGGTCGTGCT GCTCTTTAGC GCTTTATTTG 420GGGTTTTTGA AACGCCCTTA TAAAGCCGCT TAA 453(2) SEQ ID NO 67 information

Sequence properties:

(A) length: 219 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...219

(xi) sequence representation: SEQ ID NO 67: ATGATGGATT TAGAAAGTTT GAGAGGTTTT GCGTATGCGT TTTTTACCAT TCTTTTTACG 60CTCTTTTTGT ATGCTTATAT TTTTAGCATG TATAGAAAGC AAAAAAAGGG CATCGTGGAT 120TATGAGCGAT ACGGGTATTT AGCGTTAAAT GATGCTTTAG AAGACGAGTT GATTGAACCA 180CGCCATAAAG AAGTTCATGA TAAAGGCATA AAGGAAAGT 219(2) SEQ ID NO 68 message

Sequence properties:

(A) length: 300 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...300

(xi) sequence representation: SEQ ID NO 68: GGAAATTTAA TGGGACAAAC TAAAGAAATT ATAACGACGC TTTTACCCCT TTTGGTGTTG 60TTTCTTATTT TTTATTTTTT GATCGTTCGC CCGCAACGCC AACAGCAAAA AAAGCATAAA 120GAaATGATAG AGGGCTTGAC TAAGGGCGAT AAAATTGTCA CTCAAGGAGG GCTGATCGTT 180GAAGTGCTTA AAGCGGAAGC GAATTTTTTT AGCGTGAAAC TCAATGATGA CACCACCGCT 240AAACTTTCTA AAAACTATGT AGCGTTCAAA TTAGACGAAG AAACAACACC CAACAACAAC 300(2) SEQ ID NO 69 information

Sequence properties:

(A) length: 477 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...477

(xi) sequence representation: SEQ ID NO 69: ATGAAACTTT TTAACCCTCG TTTAATCGTT TTTATATTCG CGCTTCTTTT AGGGGTAGGG 60TTTTCTGTGC CTTCTTTGCT AGAAACTAAA GGCCCTAAAA TCACTTTAGG TTTGGATTTA 120AGGGGGGGGT TGAACATGCT TTTAGGGGTG CAAACCGATG AGGCTTTAAA AAACAAGTAT 180TTAAGCCTAG CGTCTGCTTT AGAATACAAC GCTAAAAAGC AAAATATCTT GCTTAAAGAC 240ATTAAATCCA GTTTAGAGGG GATCAGTTTT GAGCTTTTAG ATGAAGATGA GGCGAAAAAA 300TTAGACGCGC TTTTATTGGA ATTGCAAGGT CATAGCCAGT TTGAAATCAA AAAAGAAGCG 360GAGTTTTATA GCGTGAAACT CACCCCTTTA GAGCAAGAGG AATTGCGTAA AAACACGATC 420TTGCAAGTGA TAGGGATCAT TCGTATCCGC TTGGATCATT TGGCTTGGCA GAGCCTG 477(2) SEQ ID NO 70 information

Sequence properties:

(A) length: 264 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...264

(xi) sequence representation: SEQ ID NO 70: GGGAATGTTA AAGTGAaTAA AAAGCACCGC TTGGCTTTTT TAGGGCTAAT TGTTGGGGTT 60CTATTCTTCT TTAGCGCGTG CCAACACCGC CTGCACATGG GGTATTATTC AGAAGTTACA 120GGGGATTATT TGTTCAATTA TAATTCCACT ATCGTGGTGG CTTATGACAG AAGCGATGCG 180ATGACTTCTT ATTATATCAA TGTGATTGTT TATGAATTGC AAAAaTTAGG CTTTTATAAT 240GTCTTCACGC AAGCGAATTC CCGC 264(2) SEQ ID NO 71 information

Sequence properties:

(A) length: 495 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...495

(xi) sequence representation: 71: AAAGCGTTGA TGGTAGGAAT GAAAACTGGA GCATGGACCG GTTTAAAACT TTTTGCACAG 60CCTTTGTTGG TGGTTTTAGC GTTCATGTTG TTGTATGCTT TAGCGCATGC TGTGCTTGGT 120TTTTACGTGA AAAAAGACAG CGCTCCAATG AGTCCAAATG TAGAAAAAAG CGAGACAGAG 180CGCCAAAACA GCACGTTTTC GCCTAAAGAA GAAGCCAACG CAACCACAAC CGCCACAGAA 240CAAAACCCCA CCAAAGACAC AGTGCCACCT TTAGACACAG CCACACAAAA ACAAGAGATT 300AAACAAGAGA TTAAACAAGA GATTAAACAA GAGATTAAAC AAGAGATTAA ACAAGAGATT 360AAACAAGAGA TTAAACAAGA AACTAAACAA GAGCAAGAAA AAGAAAATAA GCCTAAACAA 420 AACkGTGTGTCT CGCCCGTTCK AAACGATCAA AAAACCCCCA CAACCCCCTT AATGGGTAAA 480AAAACCTCTA GAGTA 495(2) SEQ ID NO 72 information

Sequence properties:

(A) length: 291 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...291

(xi) sequence representation: 72: ATGCTTTATG CATCAAAAGC GCGTTTATTT TTACAAATCA AAGGAAAGTT TATGT [ AAGA 60ATTTTAATCC CCTTACTCAT TATTGTGTGG CTTTTATGGC GTTTGTTTTT GAGGCAAAAA 120CCCCACAAAG ATGACCACAG AGACAACCAC TCTTACACGC AACAAACCCC CAAAGAATTA 180GAAGATCACA TGATTGTATG CTCTAAATGC CAAACTTATG TCTCTAGTAA AGACGCCATT 240TATAGTGGGG CGGTAGCCTA TTGCAGTGAA ACTTGTTTGA AGGATAAGGG G291 (2) SEQ ID NO:73 information

Sequence properties:

(A) length: 252 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...252

(xi) sequence representation: SEQ ID NO 73: AAAACAATCA ATAAATTAAG GATTATAATG AAACCAACGA ACGAACCTAA AAAACCTTTT 60TTTCAAAGTC CCATTGTTCT TGCGGTTCTT GGAGGGATTT TACTCATTTT TTTCCTACGC 120TCTTTCAATT CTGATGGCAG TTTTTCGGAC AATTTCTTAG CTTCTAGCAC TAAAAATGTG 180AGCTACCATG AAATCAAACA ACTCATCAGC AATAATGAAG TGGAAAATGT AAGTATCGGT 240CAAACTTTAA TC 252(2) SEQ ID NO 74 information

Sequence properties:

(A) length: 690 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...690

(xi) sequence representation: SEQ ID NO 74: TTCAAAAATA ATAAGACACC CCTAACTTTT GAGCGTGATA AAGGGTCATT GGATGGTTTG 60AAAAAAGAAA GACAAGGATT TTACAAGCAA GTGCATTATT TAAGAATTTT AATACTGAGT 120ATGAGTTTTT TAAATATTTT AAATGCTGAA AATTTGAGTT ACATGTCTTC TTCTTATCAA 180ATAGGCACGG TGTTTATGCG CCCCTTAAAC ACCAACAAAC TTTTACAAGG GGCTTCAATC 240CTTCAAGGCT ATGAAGTGAA TCCTAAAAAC GACTGGGCTT ATTCTAGGTA TTATTTCTTT 300ATAGATTATG GTAATGTGCT TTTCAATAAC GATTCCACTT TGCAAGCGAA CATGTTCACT 360TATGGGGTGG GAGGAGATTT TATGGTCGCT TACGCTAAAA ACCCTATCAA CCGCTGGGCT 420TTTTTCTTTG GTTTGCAACT AGCGGCTAAC ACATGGATAC TCAATAATAA AGTCAAAGAT 480TTGGTGGTGA ATACTTGGGA TTCATTGAAA GATTTCAATT TTCATAACAC TTATTTTAGG 540GCTATCGGGA AATTTGGGGT GCAGTTTCGC ACGATCGTTT TGTATCATAA GGTGGATGTG 600GAAATTGGCA TGAAAATCTT TTTAACGCCT GAAAGGCGCA GCTTGTTTGA AAGGAGTTTT 660TTGTTTTTTG TTTCGCACTC GTGGCATTTT 690(2) SEQ ID NO 75 information

Sequence properties:

(A) length: 627 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...627

(xi) sequence representation: SEQ ID NO 75: GGAATTTGTT TGAAGTTTCA AATTGTGAGT TTGTTATTGG CTTTTTTATT AGCCTCTTGT 60TTGCCCCCTA AGGGCCATCA TTCTGGTTTG GTGAATATGT ATATTGCGCA TCAAGGCCAG 120AGCGTACGCA CTTATTGGCG CAAAGTGGAT AGAGGAGTTG TCGCCAAACA CAATGAAACG 180CTTAAAGAAA ACCCCAAAAT AAAGCTCAAA GACCCTAAGG GGCCTTTGTT CATGCTAGGG 240AGCAATCGTT TCATGCTTTT ATGGAAAAAC CGCTATACTT TAGCTAAAGT CCAATCGTTC 300AAGCTAGAGC CTGGGTTTTA TTACTTGGAT TCTTTTAGCG TGGAAACTCA AAAAGGCATC 360TTGCAAAGCG CTCCTGGCTA TTCATACACC AAAAATGGCT ACGATTTTAA GAACAACCGC 420CCCTTTTTCC TAGCCTTTGA AGTCAAACCT GACAGCAAGA TCGTTCTCCC TAGCGTGGAA 480TTGAGCTTGA TTAAAACCCC TAGAGGCTTT TTAGGGGTGT TTTTATTTGA CAACAACGAA 540AAGGGGGCTA ATACCCCATG GATTGAGGGG AGCTTGAATT TAAAGCTTAA AAACGCTTCT 600TTTAAAGACG CATGGGAGTT GGAACGA 627(2) SEQ ID NO 76 information

Sequence properties:

(A) length: 510 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...288

(xi) sequence representation: SEQ ID NO 76: AAACCCTTTG GCTATCTCGG GCTATTGTAT AAGCAAGGGA CGCAAAAAAA CCCTCACAGC 60TATGTGGGGG CTCCAGCGCG TCTTGGGGTG GATTTTTCTT ATAGCAATGG GTGGTCGTTT 120GGTATTGGGG CTATTGGGGC TTGGAATATT TATAACAAAC AGCGTTTGGC TAACCTTTAC 180ATCAGTCTAG GGAATTTTTT TGGTAACCCT AACAACGTTA AGCCTTATTT GAGCGCCGGC 240GATGTTTCTG ATGCGTATCT TCAATACGCT AACCAGCGTT TTAAAATCGC TTTAGGGCGT 300TTTAATACCG ATTTTGTGGA TTTTGATTGG ATAGGGGGCA ATATTCAAGG GGTCTCTGTG 360GCTTTCAAGC AAAATTCCAT GCGTTATTTT GGGATTTTTA TGGATAGCAT GCTTTATAAT 420GGGCATCAAA TCAATAAAGA GCAAGGGAAT CGGATCGCCA CTTTCCTAAA CGCTCTAGCT 480CTTATGATCC TGTGTCTAAA CGCTTGTATG 510(2) information SEQ ID NO 77

Sequence properties:

(A) length: 585 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...585

(xi) sequence representation: SEQ ID NO 77: TTAGGATCAC CCATGCAATT TCAAAAAACC TTATCTTCCT TATCTTTATT TTTATCTTTA 60TCTTTATTCT TATCTTTTAG TATCGCTGAA GAAAATGGGG CGTATGCGAG CGTGGGTTTT 120GAATATTCCA TTAGTCATGC CGTTGAGCAC AATAATCCCT TTTTAAATCA AGAACGCATC 180CAAACGATTT CTAACGCTCA AAACCAAATC TATAAACTCA ATCAAATTGA AAATGAAATC 240ACAAACATGC AAAACACCTT TAACTACACC AACAACGCTT TGAAAAACAA TGCTAAATTA 300ACCCCCACTG AAATGCAAGC CGAACAATAC TACCTCCAAT CCACCCTTCA AAACATTGAA 360AAAATAGTCA TGCTTAGCGG TGGCGTTGCG TCTAACCCTA AACTAGTCCA AGCGTTAGAA 420AAAATGCAAG AACCCATTAC TAACCCTTTA GAATTGGTAG AAAACTTAAA AAATTTAGAA 480TTACAATTCA GCCAATCTCA AAACAGCATG CTTTCTTCTT TGTCTTCTCA GATCGCTCAA 540ATTTCAAATT CTTTGAACGC GCTTGATCCC AGCTCTTATT CTAAA 585(2) SEQ ID NO 78 information

Sequence properties:

(A) length: 216 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration:ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...216

(xi) sequence representation: SEQ ID NO 78: AAAGGCAAGG TCATGAATAG TTCTAACCTC AAAAATTGGC TATTCCCCAC TATTTGCTTT 60TTTTTATTTT GTTATATTTT AATTTTTTTG ATATTTTTTA TGTTTAAAAA CTTGCAATCG 120CAATCTTTTG GCTCTGTGGC AGAAACCGGA AAAAAACCCA TCACCACCAC CAAGAAATTT 180GGTAAGGAAT TGCAAAAACA GATTTCAAAA ATCCAT 216(2) SEQ ID NO 79 information

Sequence properties:

(A) length: 834 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...834

(xi) sequence representation: SEQ ID NO 79: TTGATGCGTA AGGTTTTATA CGCTCTCATG GGCTTTTTGT TGGTTTTTAG TGCTTTAAAA 60GCCGATGATT TTTTAGAAGA AGCGAACGAA ACAGCCCCAG CGAATTTAAA CCACCCCATG 120CAGGATTTAA ACGCCATTCA AGGGAGCTTT TTTGACAAAA ACCGCTCCAA AATGTCCAAC 180ACTTTGAACA TTGATTACTT TCAAGGGCAA ACTTATAAAA TCCGCTTGCG TTATGCGATG 240GCGACTTTAT TGTTTTTTTC AAAACCCATT AGCGATTTTG TTTTGGGGGA TAAGGTGGGT 300TTTGATGCGA AAATTTTAGA AAGCAATGAT CGCATTTTAC TCATCAAACC CTTACAAATC 360GGCGTGGATT CTAATATCAG CGTGATTGAT AGCGAGGGTA AGATTTTTTC TTTCTATGTG 420TTTTCTACCA CTTTCACCAG CTCCAAACAC CCTAATTTAC AGGTTTTTAT AGAAGATAAA 480AACTATTACA CTAACGCTTT TATCAAGCCC CAAAAAGAAA ATCAAGAAAA TATGTCTGAA 540AATGCCCCTA AAGATGCCCA AAAAAATAAT AAGCCCCTAA AAGAAGAAAA AGAAGAAACT 600AAAGAAAAAG AAGAAGAGAC TATAATTATT GGCGATAACA CCAACGCGAT GAAAATTATT 660AAAAAAGACA TCCAAAAAGG CTATAAGGCT TTAAAAAGCT CTCAAAGGAA ATGGTATTGT 720TTATGGGCTT GTTCTAAAAA ATCCAAACTC TCCTTAATGC CTAAAGAAAT CTTTAACGAC 780AAGCAATTCA CTTATTTCAA ATTTGACAAA AGATTAGCAC TCTCTAAATC CCGG 834(2) SEQ ID NO 80 information

Sequence properties:

(A) length: 180 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...180

(xi) sequence representation: SEQ ID NO 80: TATCGTGAGA TGGATTATGC GGTGTTTAGC ATGACAATCC ACCCTGATGT GAGCGCCCGT 60CCGCAAGTGT TGCTCATGCA TGAAAAAATC ATTGAGCATA TCAACCAGCA CGAGGGCGTG 120GCTTGGGTAA CGTTCAATGA AATCGCTGAT GATTTCTTAA AACGAAACCC TAGGAAAAAA 180(2) SEQ ID NO 81 information

Sequence properties:

(A) length: 237 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...237

(xi) sequence representation: SEQ ID NO 81: CTTGTGTTAC AAGGGGCTGA GGTTTTAATC TATCCTAGTG CGTTTGGCAA AGCTAGGGCT 60TATAATTGGG ATTTGTTGAG CAAAGCTAGA GCGTTAGAAA ATGGCTGTTT TGTGTGCGCT 120TGCAATCATA GTGGGGAAGA AACTAACGCT AAATTAAAAC AAACGCTAGA ATTTGCCGGT 180GATTCAAGGA ATCATCGCAC CCAATGGGAA AATCATCGCC CAAGCCACCA AGCTTAA 237(2) SEQ ID NO 82 information

Sequence properties:

(A) length: 183 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...183

(xi) sequence representation: SEQ ID NO 82: AATTTGCCGG TGATTCAAGG AATCATCGCA CCCAATGGGA AAATCATCGC CCAAGCCACC 60AAGCTTAATG AAGTCATTAT CGCCGAAATG GATTTAAACG AAGTGGCACT GCAACGCCAA 120AAAATCCCTT ATTTACAAGA TTTTGACACC AAACTCACCA AAAAGGGGTT TGGAAAACTC 180ACT 183(2) SEQ ID NO 83 information

Sequence properties:

(A) length: 486 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...486

(xi) sequence representation: SEQ ID NO 83: ATCATTATGT TTGGCATGGG CTTTTTTGAA ATCCTTGTGG TGTTGATTGT AGCGATTATT 60TTTTTAGGAC CAGAAAAATT CCCTCAAGCT GTCGTGGATA TAGTGAAATT TTTTCGCGCG 120GTTAAAAAAA CGCTCAATGA CGCTAAGGAC ACTTTAGATA AAGAAATCAA TATTGAAGAA 180ATCAAAAAAG AAACCTTAGA GTATCAAAAA CTCTTTGAAA ACAAAGTGGA GAGTCTTAAA 240GGCGTTAAGA TTGAAGAATT AGAAGACGCT AAAGTAACTG CAGAAAATGA GATTAAAAGC 300ATTCAGGATT TGATGCAAGA TTATAAACGC AGCTTAGAAA CCAACACGAT TCCTAACCAT 360TTAAATGAAG AAGTTTCCAA TGAAGAAGCT TTAAATAAAG AAGTTTCAAG CGATGAATCT 420CCTAAAGAAG TCCAATTAAC AACCGATAAC AACGCCAAAG AACACGACAA AGAAAAAGAG 480CATGTT 486(2) SEQ ID NO 84 information

Sequence properties:

(A) length: 555 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...555

(xi) sequence representation: SEQ ID NO 84: CGCTATCGGT CCTTTAGCCG CAATCAGTCA AACTTTAGAA GATGCGAGCA GCCCTATGGG 60AGTACTTTAA ACTCTGTGCC GTTGTGGATT ATGGTAGTAG GGGCAGCTGG GATCGCTTTA 120GGCTTGAGCT TGTATGGGCC AAAGCTCATT AAAACGGTGG GGTCTGAAAT CACAGAATTA 180GACAAAATGC AACTTTTTTG CATCGCGCTT TCAGCGGTCA TCACCGTGCT TTTAGCCTCT 240CAATTAGGCT TACCGGTAAG CTCTACGCAT ATTGTGGTGG GCGCGGTGTT TGGGGTGGGC 300TTTTTAAGGG AGCGTTTGAG GGAGCAATCC AGAAGGCGTT TTGCTAGAAT CAGAGACAAC 360ATTGTAGCGG CGCACTTTGG GGAAGATTTA GAAGAAATTG AAGGCTTTTT AGAGCGCTTT 420GATAAAGCCA ATTTGAAAGA AAAATCGCTC ATGCTAGAGA GCTTGAAAAA AAGCAAGAAC 480ACCGCTATCG CTTTGGAATT GAAAAAGAAA GACAAAAAGT CGCTTAAAAA AGTGTATAAA 540GAAGAAGTGA TCAAA 555(2) SEQ ID NO 85 information

Sequence properties:

(A) length: 315 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...315

(xi) sequence representation: SEQ ID NO 85: GCGCAAATCT TTGTGCGTTT CAATTATGTT TTAGGCGCGA TCGGTTTTGT GGTGTTACTT 60TATGAAATCA TTTCGTTTAT CTACTATAAA AGATCGTTAG TGTATTTGAT CCTTGGCGTG 120GCGATAGGGG CGTTGTGTTT GCTCTTTGTT TTTTATTACA CGCCTTATAT TTTAAACGCT 180CAAAAGGTGG GTGAAGTTGC GCTTCAAAGT GCTGAATTTG CCCGCTCGCA CGCTCAAAGC 240GAATGGCTGT TTAAGGAATT GTTTGTGCTG GTGTGTGCTT TGTTTTTTTG GCGTTTGTTT 300GGGAAAAATG CGCTT 315(2) SEQ ID NO 86 information

Sequence properties:

(A) length: 348 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...348

(xi) sequence representation: SEQ ID NO 86: AAGGCTTGCA AGATGAAGTG CTCAAGCTTT ACCTCTAATA GCGTCTTAAA CTTTTTTGTA 60GTTTTGTCTT TCATCACGAT AGGGCTAGTG TTTTTCTTTT TGCGTTCCCA ACCAACTAGC 120GTAGTTTCTA AAGAAAATAT CCCTAAAATT GAATTAGAAA ATTTTAAAGC GTTTCAAATC 180AACGATAAAA TCCTTGATCT GTCCATAGAG GGCAAAAAAG CCCTACAATA CGATGATCAT 240GAAATCTTTT TTGATTCTAA AATCAAGCGC TATGATGAAG ACACCATTGA AAGCGTTGAG 300TCCCCTGAAG CCAAACGGCA GCAGGATTTG TATTTCTTCC CTAACGGG 348(2) SEQ ID NO 87 information

Sequence properties:

(A) length: 315 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...315

(xi) sequence representation: SEQ ID NO 87: AATCAAACAA AGCCAGAAAG AAAAGAAAAA ATTCCCCACT TTCAAAGGAG GGTTTTAATG 60CGTTGGTGGT GTTTTTTGGT GTGTTGTTTG AGCGTTTTAA GCGTGATGGA CGCTAAAAAA 120TTAGAGAATA AAGGCTTGAA AAAAGAAAGA GAGCTTTTAG AAATTACCGG CAACCAATTT 180GTAGCGAACG ACAAAACCAA AACCGCCGTT ATTCAAGGCA ATGTGCAGAT CAAAAAAGGT 240AAAGACCGGT TGTTTGCGGA TAAAGTGAGC GTGTTTTTAA ACGATAAACG AAAGCCAGAA 300CGCTATGAAG CAGCA 315(2) SEQ ID NO 88 information

Sequence properties:

(A) length: 957 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...957

(xi) sequence representation: SEQ ID NO 88: AAAGAAAGTA ATTCTATGGA CTTAGACAAA CTCAAAGATT ATAGGGCTTT AAGAAACGCT 60ATTTTAAGGC TATTGCCTTA TTTAGATAGC GGTATTACAG AGCTAATTAT GAATAAAGAA 120AAAGAAATTT GGCTCTATAA GCTTAATGGA GTAAGAGAAA AAGTCTTTGA TGAAAATTTA 180GACAAAGCCT TTATTCTGGG GTTTGGGGAA CAATTAGCGA GTTTTAGAGA TTTGTTTTTT 240AATGCTAATT ACCCCACCCT TAATACTTCC ATTCCTACTT CTAGATACAG AGTGAGCATG 300AACCACTTTG CTATTAGTGC GGATAATGAA TTGAGTTTGA ATATTAGAGT GCCAAGTGAT 360AAAAAGTTTG ATTTAAAAGC TTTCAAGCTT TCTAGTATCT GTCAATACGA TTATGAGTAT 420TTAAAAAACT TAATGATTGA TGGCAAAAAC TTACTCATTA GTGGAGGCAC AGGCAGTGGA 480AAAACGAGTT TTTTAAACGC TCTAATTGAG TTTATCCCCA AACACACACG AATAGTAAGC 540GTTGAAGATA GCGAAGAATT AGATTTAAGA GCGTTTGAAA ATCATAAATC CTTGTTAGTG 600GATAAAACTG AAAGCTCTAA ATTTACATAT GAAAACGCCT TGAATATGGC AATGAGAATG 660TCTCCTGATA GGCTTATGGT AGGCGAGATT GACACACGAA ATTCCATGCT CTTTTTAAGA 720TTTGGAAACA CTGGGCATAA AGGCATGGTT TCTACTTTAC ATGCAGATAG TGTGCATGGG 780GTTATAGAGG CGATTGCTTT AAATTTACAA ATGAATAAAA GTGGTTTAGA TGTCAATGTA 840GCAAAAAAAT TCTTTAAAAG CAGTGTGGAT GTTGTCGTTC AAATTGTATT AGATAAAGCC 900ACTAACACCA GATACATTCA AGAAATCTTA CCAGCAAAAG ATTTAAGAGA TAGTCTA 957(2) SEQ ID NO 89 information

Sequence properties:

(A) length: 261 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...261

(xi) sequence representation: SEQ ID NO 89: GGAGTTAAAG CAATGAATTA CGATGTTTTA ATGGGATTTT TAGCACTAAT CTTGCTAATT 60CTTTGGTATG CCTATGGATT AAGGCAATAT CTTAAATTAA AAGATAAGAA TAAGAGATTA 120AAAGAGAAAT TACAACGCTG TAATTGTAAT ATTAAAATTC CTAGTATTCT TGAAATGGCG 180CATAAACCTA TCATTATGGA TATTAAGGGG GAATTGCTAC CACATCTTAC AGAGAGTTAT 240AGAAAATCAA AATTTAAGGA G261 (2) SEQ ID NO 90 information

Sequence properties:

(A) length: 285 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...285

(xi) sequence representation: SEQ ID NO 90: CTCTCAAGGA ATGGCGTGGT CTCTAGCGTG AGTTCTGATG GCTCTAAAAT TTTAATGTCT 60TTAGCCCCTG ATGGCCAACC GGATGTTTAT TTGTATGACA CGCATAAAAA AACTAAAACC 120AAAATAACGC GCTATCCGGG GATAGATGTT TCAGGCGTGT TTTTAGAAGA TGACAAGTCT 180ATGGCTTTTG TTTCAGATAG ATCCGGTTAT CCTAACATCT ATATGAAGAA ATTGGGGTTA 240AAAGAGAGGC GGAGCAACTC CTTTATGAAG GAAGAAGCAA TGAAT 285(2) SEQ ID NO 91 information

Sequence properties:

(A) length: 438 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...438

(xi) sequence representation: SEQ ID NO 91: GGGGATAAAA TGCTAAAAAA GTTATTGCTC ATTTCACTAT TTTTAGGGTT TTTAAGAGCA 60GAGGGCGAAC ATTATGAAAT CATCGCTGAA CTTTCCAAGG CTTTTTTGAA AGCCAAAGAG 120GTTTTGACTG CGATCAATAA AACCTATAAA ACCTGTATTG AAACCGGGCA TGATCGCACT 180CAAATACGCC TTCAAAACGA TTTTTTAGAG AATTTGTCTC AAACAGAGCA ACAATTTGAT 240GATTATTTTG AAAAGGATTT TAAAAGCGTA GGGGTTTTAA AAACCTTGCT TAAAGACATC 300CAATCCTTAG AAAAAACTTC CAACAAGCTC GTATGCGTTG CCCCAAAAAA CGCTAAAAAT 360TTTGAAATAT TAGAGGGAGC GATAACGCAA ATCATAGGAT TAGAAGAGCA GATGAATCAA 420TTTATCAATG GCGCGAAA 438(2) SEQ ID NO 92 information

Sequence properties:

(A) length: 345 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...345

(xi) sequence representation: SEQ ID NO 92: ATCCAAAGGC TAAAAGAAAT GCTTAGAAAT CAATTTCGTA TCGTGTTTGT CACCTGCATT 60GTCGCTAGCA GTTTGCAAGC TCAAGAAAAT ACCCCCACTT TGGGTAAGGT AACCACTAAG 120GGTGAAAGGA CTTTTGAATA CAACCATCAA ATGTATACTG ACAGGAAAGA GCTCCAACAA 180CGCCAAAGTA ACCAAACCCG TGATATTTTT AGGACTAGGG CGGATGTGAA TGCGGCCAGT 240GGGGGCTTAA TGGCGCAAAA AATCTATGCC AGGGGGATTG AGAGCCGTCT CTTAAGGGTA 300ACGATAGATG GCGTCGCTCA AAATGGTAAC ATTTTCCACC ATGAC 345(2) SEQ ID NO 93 information

Sequence properties:

(A) length: 792 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...792

(xi) sequence representation: SEQ ID NO 93: GCGGTAAGTT GGATAATGGC GTGTTGGCAT AAAAGATTGG CAGTTGGTTG TTGTATCGTT 60TTATTGTCAT GCGTAATGAG TGCTAATAAT GTTAGTATCG TTAGAGACGA TCCGCCCCTT 120GATCCAACGC TCCCTGCATG GATTTATTCT GTTGCGTTAT TGAAAGTGTA TTTTAGCGAT 180GGGACTTATA AAGAAGGCTA TGCGACTTTG CTAGAAAACG GGCGTTATAT CGCTTCTTCT 240GAAACGCTCT ATTCTAATGG CTTGTATCCT AAAATGATTT TAGCCAAAAT GCAAGACAGC 300AGTGCTAAAG AGCTGATTTG CATAGCCAGC TTGCACCTTG AAGCGATGGA TAGGGATCAA 360GGGCTTTCGC TCTTAAAAAC CGCCGATTTT AGAGACGATT ATTGTCATAA AAGAGAAGAG 420AGCTATTATC ATGCAAGGAT TTATGCCAAA TACGCTCAAA CTTTCCATTC AAATCCTTAT 480ACCAATCAAA AAACACCCAC TTCCGATCTC TACTACCCGG CGTTAAATGA GGGGAATTCT 540TTTTCCATAC AGACAACGGA CATTTCTGTG GCTGAACTTT TGAAATCTAA AAAGTTTCTT 600TCGCTTGATG CTTCTTTTAA AAAGGGGAGC GTGTTGTGGG GAGGGAGACC TTATTTTAGC 660GAGGTAGGGG AGTTTATGGG AATGACTAGC AGCACTTTAG AAAACCAAGA AAGTTTGGTG 720ATTATCCCTA AAGAAAAGAT TGCGCGATTT TTAAGCGCTC TAAAAAATCA AAATATTTTT 780CCAAACATTC CC 792(2) SEQ ID NO 94 information

Sequence properties:

(A) length: 441 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...441

(xi) sequence representation: SEQ ID NO 94: CTTGGAGGAC TAGACATGTA TAAATTAGGA ATATTTTTAT TAGCCACCTT ACTATCAGCT 60AACACGCAAA AAGTGAGCGA TATTGCTAAA GACATCCAAC ATAAAGAAAC CCTTTTGAAA 120AAAACCCATG AAGAAAAAAA CCAACTGAAC AGTCGTTTGA GTTCTTTAGG CGAAGCGATC 180CGCTCTAAAG AGCTTCAAAA GGTTGAGATT GAACGCCAAA TGGTCGCCTT AAAAAAGAGT 240CTTGAAAAAA ATCGTAACGA AAGTTTGGTG CAAGAAAAAG TCCTAACCAA CTACCGCAAG 300TCTTTAGATC ATTTGCAAAA ACAACGATCG TTTTTACAAA AGAGAGTGTT TGATACGCTT 360TTAGAGGATT TTCTTTTCTC ACAAGCCCTA AAGGGGCAGA ATTTAGCCTC TTCTAATGAT 420GTGATTTTGC TAAGTGGCGT T441 (2) SEQ ID NO 95 information

Sequence properties:

(A) length: 1569 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: isnot

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1569

(xi) sequence representation: SEQ ID NO 95: TATATTCCAT TCAATTTATT TCAAGGACAA ACAAACATGA AAAAACTTCT TTATACCATG 60CTCGCGCTTC TTTTAATCGG CCTTTTAACG GCCTATCTTA TCCTTTTTAC AGAATGGGGG 120AATAAGATCA TCGCTTCGTA TATAGAGAAA AAAATCAATC CGAACGAGCG TTATTTGAGC 180GTTAAAACCT TTAAATTGAG ATTCAACTCT TTGGATTTCA AAGCTCAAGC CAACGATGAT 240TCCACGCTCA TTCTTAAGGG GGATTTCTCG CTTTTAACGC AAAGCGTAAA TTTGGATTAC 300CACATAGACA TTAAAAATTT ACGCTCTTTT AAGGATTTGA TACCCTACCC CTTAAGAGGG 360GCTATTGTTA CTTCTGGGAA TATCAAAGGG CATAGAAAAG CCCTTGTAGT TCAAGGCGTC 420TCCAATGTCG CTCAATCCCA CACTGCCTAC AACGCCCTTT TAGATGATTT CAAGCTTTCT 480CACTTAAGTT TGAACGCAAA AGACGCCAAT TTAGAAGATT TGCTTTATTT AATCAACCGC 540CCCGCTTATG CGAACGCAAA AGTGTCCTTA CAAGCGGATT TTAACTCTCT AAAGCCCTTA 600GAAGGGCATT TGATCCTAAC AGCTAATAAC GCTTTAATCA ATAACGCCCT AATCAATCAA 660ATCTTTCATT TAAACCTTAA AGACACGCTC GTTTTCAACC TCTCGCACTC AAGCGATTTT 720AAAGGAAACA AAGCCATCAG CGATACCACC CTAACTAGCC CTTTAGTTAA TTTCACAGCC 780CTAAAAAGCG AATATTCTTT CCCTGCTTTA AAACTCAACG CCCCCTACAC TTTAGAAATA 840CCCCATCTAG CCAAACTCCA AAACATTACC AACCACCCCT TAAAAGGGAG CTTGACTTTA 900AAAGGCGATA TAGAGCAAAG CCCTAAACTC TTAAAAGTCA GTGGCCATTC AAATTTACTA 960GACGGCGCGC TAGACTTCAC GCTTTTAAAT AAAGATTTGA AAGCCCGTTT TTCCAATATT 1020TCCACTTCAA AAGCCTTAGA TTTATTCCAT TACCCTAAAT TTTTCCAATC CATTGCAGAC 1080GCTAACTTGG ATTATGACCT TATCTCTAAG CAAGGCGTGT TGAAAGCCAA TCTCAAGAAC 1140GCAAGATTCC TCAAAAATGC ATTCAGCGAT TTCCTCTATT CCATTTCTCG TTTTGATATT 1200ACTAAAGAAA TTTATCACGA TGCCAATCTA GTAAGCCAAA TCAACCAGCA ACGCCTGCTC 1260TCTGATTTGA GTTTAAAAAG CCCCAAAACC CAATTGAAAA TCCATAACGG CTTGTTGGAT 1320TTAAACACCA AGCAAATGGA CATACTCATG GATGCGGAAA TCTTAAAATT CATCTTTAAA 1380ATGAAACTTC AAGGCAGCAT GCACCAGCCA AAATTTTCCC TCATTTTAAA CGAAAAAGCC 1440ATTCAGCAAA ACCTGCAACA AGGCTTGAAA GAAATCCTTA AAAACGACAC CCTTAAAAAA 1500GGTTTAGATC ATTTGCTTAA AGATGATAAA CTCAAAGAAA AGCTTGAAAA AGGGCTTAAG 1560GGGCTTTTT 1569(2) SEQ ID NO 96 information

Sequence properties:

(A) length: 666 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...666

(xi) sequence representation: SEQ ID NO 96: GCATTTCTTT ATATTCATTC AATAGCGCTT GCGCGGGTAA TTCTTCAACT AAAACCTCTA 60CTAACAATTC ATCTGAATGC AAAATCTCAA TCCTCCCTAA AAAACAAAAT CACTCTTAAG 120AATAAGCTAA ATCATGCTAG AATTATACTT GAATTTATTC CTAGTTTAAT TTATTTCTTA 180ATACAAAAGG TGAGCGTTTT GAAACATTTA GCCCCACTCA TTCATATCCC TTTTAAAGCC 240TTATGGCTAG GCACAGCCTT AAGCATGTTC TTAAGTTTGA ATTTGAACGC TGAAGAAAAC 300CCTACTAAAA CAGAGCCTAA GCCCGCTAAA GGGGTTAAAA ACAAGCCCAA ATCGCCTGTT 360ACTAATGTCA TGATGACCAA TTGCGATAAC CTTAAAGACT TTAACGCTAA GCAAAAAGAA 420GTTTTAAAAG CCGCTTATCA ATTCGGATCT ACAGAAAATT TAGGCTATGA AATGGCGGGC 480ATTGCGTGGA AAGAATCATG CGCAGGGACT TATAAAATCA ATTTTTCGAA TCCGAGTGCG 540GGCATTTACC ATGCGTATAT CCCTAGCGTT TTAAAAAGCT ATGGGCATAA TAATAGCCCC 600TTTTTGCGTA ACGTGATGGG GAGAATTGCT ACATTAAAGA CGATGCGTTT GCTTCTGAAG 660TGGCCC 666(2) SEQ ID NO 97 information

Sequence properties:

(A) length: 897 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...897

(xi) sequence representation: SEQ ID NO 97: TTAGTTATAA TATCGCTACT AACAACACTC AAGCTAAAAT CCATTAAGGA AATCAGTATT 60AAAAAATTTA TTCTATCTTC TCTTGTTTTC GCATGTATCA ATACCGGCGT TGAAGCTTTA 120GAAAATGACG GCTCTAAACC AAACGATTTG GCTTCTCCAA AAGAAACCCC AAAAGAGGCT 180CAAAAAAATG AAGCTCAAAA CGAAACCTCT CAATCCAATC AAACGCCTAA AGAAATGAAA 240GTCAAGTCCA TTTCTTATGT CGGGCTTTCT TACATGTCTG ACATGCTCGC TAATGAAATT 300GCAAAGATTC GCGTGGGCGA TATGGTGGAT TCTAAAAAAA TAGACACCGC TGTTTTAGCT 360TTGTTCAACC AAGGGTATTT TAAAGACGTT TATGCCACTT TTGAAAACGG CATTTTAGAG 420TTTCATTTTG ATGAAAAAGC CAGGATTGCC GGGGTAGAAA TCAAGGGTTA TGGGACTGAA 480AAGGAAAAAG ACGGCTTAAA ATCCCAAATG GGGATCAAAA AGGGCGACAC CTTTGATGAG 540CAAAAATTAG AGCATGCTAA AACGGCTTTA AAAACGGCTT TAGAGGGGCA GGGCTATTAT 600GGGAGCGTGG TGGAGGTGCG CACAGAAAAG GTCAGTGAGG GAGCGTTATT GATCGTGTTT 660GATGTGAATA GGGGGGACAG TATTTATATC AAACAATCCA TTTATGAGGG AAGCGATAAA 720TTAAAACGCC GTGTGATTGA ATCTTTGAGC GCGAACAAGC AGCGCGATTT CATGGGCTGG 780ATGTGGGGCT TGAATGACGG GAAATTGCGC TTAGATCAAT TAGAATACGA TTCTTTGCGT 840ATCCAAGATG TGTATATGCG TAGGGGTTAC TTAGACGCTC ATATTTCTTC GCCTTTT 897(2) SEQ ID NO 98 information

Sequence properties:

(A) length: 864 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ featurer

(B) Position: 1...864

(xi) sequence representation: 98: GAGTTTGGTG TGAAGCGAAT TTTATTTTTT TTAGCGGCTA CGACTTTTTT GTTGAGAGCA 60GAAACGGCTT CTGCTACTAT TAACACTACA GTTGATCCCA ATGTTATGTT TTCTGAAAGC 120TCCACAGGGA ATGTGAAAAA AGACCGCAAG AGGGTTTTAA AGAGCATGGT TGATTTAGAA 180AAAGAGCGCG TGAAGAATTT TAACCAGTAT TCTGAAACCA AGATGAGTAA GGGCGATTTA 240TCCGCTTTTG GAGCTTTCTT TAAGGGGAGT TTGGAAGATT GCGTGGAGCA AAAGATTTGT 300TACTATGAGC ATAGGAATGG CAAGGTTTCT TTTGTGGTGA ATGACAGAGA AAAGTTTTAT 360AAGCATGTGC TTAAAGACTT AGGGACAGAG CTTTCACTCC CCTTGTTCAA CTGGCTTTAC 420AAAGGCTCAG ATTTTGGGGC TTTGCATGAG CAGTTTGGGG ACATGTATGA TGGGTATATC 480AAATACTTGA TCAGCATGGT TAGGGTGAGC CAAAAAGAAA AGGCTAGAAA AGTGGATGCA 540ATCGTTCTTA AAAAAATGGA AGAACAAGCT GAGAAAGACA CTAAGGCAGC ATTCCAAAAG 600AGGAGCAGTG GGGAGCTTGA AAGCCATACT GATAGCCCTG AATTTATAAG CTCTTCTAAG 660ACACAGAATT CTTCTAACCC AGATCTAGAC CCTATGACTA ACGCTAACAC GCTCAAAGAA 720ACAGCTTCAA AAGAGCCAGA GACTTCTTCA AAAAAGGAAA AAAAGCCCAA GAAAAAACGA 780CGCCTTTCAA AGAAAGAAAA GCAACAACAG GCCTTACAAC AAGAGTTTGA AAAGCAAATT 840AGCGACTCTA GTAAGTCTGA AAAA 864(2) SEQ ID NO 99 information

Sequence properties:

(A) length: 1221 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1221

(xi) sequence representation: SEQ ID NO:99: AGTCGCACCC TTTGTGCAAA AATCGTTTTA CAAAAAGAAA GGAAGAAAAT GGAAATACAA 60CAAACACACC GCAAAATCAA TCGCCCTTTA GTTTCTCTCG TTTTAGCAGG AGCGTTGATT 120AGCGCCATAC CGCAAGAGAG TCATGCCGCC TTTTTCACGA CCGTGATCAT TCCAGCCATT 180GTTGGGGGTA TCGCCACAGG CACTGCTGTA GGAACGGTCT CAGGGCTTCT TAGTTGGGGA 240CTCAAACAAG CCGAAGAAGC GAATAAAACC CCAGATAAAC CCGATAAAGT TTGGCGCATT 300CAAGCAGGAA AAGGCTTTAA TGAATTTCCT AACAAGGAAT ACGACTTATA CAAATCCCTT 360TTATCCAGTA AGATTGATGG AGGTTGGGAC TGGGGGAACG CCGCTAGGCA TTATTGGGTC 420AAAGGCGGGC AATGGAACAA GCTTGAAGTG GATATGAAAG ACGCTGTAGG GACTTATAAA 480CTATCAGGGC TTAGAAACTT TACTGGTGGG GATTTAGACG TGAATATGCA AAAAGCCACT 540TTGCGTTTGG GCCAATTCAA TGGCAATTCT TTCACAAGCT ATAAGGATAG CGCTGATCGC 600ACCACGAGAG TGAATTTCAA CGCTAAAAAT ATTTCAATTG ATAATTTTGT AGAAATCAAT 660AATCGTGTGG GTTCTGGAGC CGGGAGAAAA GCCAGCTCTA CGGTTTTGAC TTTGCAAGCT 720TCAGAAGGGA TCACTAGCAG TAAAAATGCG GAAATTTCTC TTTATGATGG CGCCACGCTC 780AATTTGGCTT CAAACAGCGT TAAATTAAAT GGTAATGTGT GGATGGGCCG TTTGCAATAC 840GTGGGAGCGT ATTTAGCCCC TTCATACAGC ACGATCAACA CTTCAAAAGT TCAAGGGGAA 900GTGGATTTTA ACCATCTCAC TGTGGGGGAT CAAAACGCCG CTCAAGCGGG CATTATCGCT 960AGCAATAAGA CTCATATTGG CACACTGGAT TTGTGGCAAA GCGCCGGGTT AAATATCATT 1020GCCCCTCCAG AAGGTGGCTA CAAGGATAAA CCTAATAGTA CCACTTCTCA AAGTGGCACT 1080AAAAACGACA AGAAAGAGAT CAGTCAAAAT AACAATAGCA ACACAGAGGT CATTAACCCA 1140CCCAATAACA CGCAAAAAAC AGAAACTGAA CCCACCAAGT CATTGATGGG CCTTTTGCTG 1200AAGGCAAAGA CTCGGTTGTC A1221 (2) SEQ ID NO:100 information.

Sequence properties:

(A) length: 489 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...489

(xi) sequence representation: SEQ ID NO 100: CAAATCTTTT GCTCCACGCA ATCTTCCAAA CTCCCCTTAA AGAAAGCTCC AAAAGCGGAT 60AAATCGCCCT TACTCATCTT GGTTTCAGAA TACTGGTTAA AATTCTTCAC GCGCTCTTTT 120TCTAAATCAA CCATGCTCTT TAAAACCCTC TTGCGGTCTT TTTTCACATT CCCTGTGGAG 180CTTTCAGAAA ACATAACATT GGGATCAACT GTAGTGTTAA TAGTAGCAGA AGCCGTTTCT 240GCTCTCAACA AAAAAGTCGT AGCCGCTAAA AAAAATAAAA TTCGCTTCAC ACCAAACTCC 300TATATCCATA ACCGCAACAA AAACAGACGC TATTCTTCAT TAAGCCCTCT TTTAAAATCT 360TCTTCTATTT GTAAAAACCC ACCTAGAATT CAAGCTATTT TGATTATCTT AAAATACAGA 420CTTTCAAAGG GTTTTAATCC TGTGGTGGTG ATACTTAGGA TCCAAAAAAT GCGGACTCTC 480CAAAAACTT 489(2) SEQ ID NO 101 information

Sequence properties:

(A) length: 603 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming:is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...603

(xi) sequence representation: SEQ ID NO 101: GGTTTAATCA CAATGGATAA AAACAACAAT AATAATCTCC GCTTGATTTT AGCGATCGCT 60CTGTCTTTCT TGTTAATCGC TCTTAATAGC TATTTTTTCC AAGAACCAAA CAAAACAACA 120ACCGAAACCA CAAAGCAAGA AACAACCAAC AACCACACAG CAACAAGCCC CACCGCGTCC 180AATACCATCA CCCAAGATTT TAGCGTTACC CAAACCATCC CTCAAGAGAG TTTGTTAAGC 240ACGATTTCTT TTGAACATGC CAAAATTGAA ATTGATTCTT TAGGGCGCAT CAAACAGGTT 300TATCTCAAAG ATAAAAAGTA TCTAACCCCT AAAGAAAAGG GCTTTTTAGA GCATGTGAGC 360CATCTTTTTA GCTCCAAAGA AAACTCGCAA CCCTCCCTAA AAGAGCTCCC CCTTTTAGCA 420GCCGATAAAC TCAAGCCTTT AGAAGTGCGT TTTTTAGACC CCACGCTCAA TAATAAAGCG 480TTCAACACCC CTTATAGCGC CTCAAAAACC ACCCTTGGGC CTAACGAACA GCTCGTTTTA 540ACCCAAGATT TAGGCACTCT TAGCATCATT AAAACCCTGA CTTTTTATGA TGATTTGCAT 600TAT 603(2) SEQ ID NO 102 information

Sequence properties:

(A) length: 204 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...204

(xi) sequence representation: SEQ ID NO 102: GGAGTTTCTA TCATTATGGT ATTGAAAACA AAATTAAAAA TTATAAGCTC GGTGATTTTG 60AGTACTTTAT TGTGGGTGGG TTGCTCAAGC GAAATGGCGA CTTATCAAAA TGTGAATGAC 120GCCACTAAAA ATACGACTGC AAGTATTAAT AGCACGGATT TATTGCTAAC CGCTAACGCG 180ATGTTAGATT CCATGTTAGG GACC 204(2) SEQ ID NO 103 information

Sequence properties:

(A) length: 528 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...528

(xi) sequence representation: SEQ ID NO 103: GCGATGAAAA ATCAAGTTAA AAAAATTTTA GGGATGAGTG TGGTAGCAGC GATGGTGATC 60GTAGGTTGTA GCCATGCCCC AAAATCAGGT ATCAGTAAAA GCAATAAGGC ATACAAAGAA 120GCGACTAAAG GCGCTCCTGA TTGGGTTGTA GGGGATTTGG AAAAAGTGGC GAAGTATGAA 180AAATATTCAG GGGTCTTTTT AGGAAGGGCT GAAGATTTGA TCACTAATAA TGATGTGGAT 240TATTCTACGA ATCAGGCTAC AGCCAAAGCT AGGGCTAATT TAGCGGCGAA TCTAAAGTCC 300ACTTTACAAA AAGATTTGGA AAATGAAAAA ACCAGAACGG TAGATGCTTC TGGTAAAAGG 360TCCATAAGCG GCACTGATAC TGAAAAAATT TCTCAATTAG TGGATAAGGA ATTGATCACT 420TCTAAAATGC TTGCCCGCTA TGTCGGTAAA GATAGGGTTT TTGTTTTAGT GGGCTTGGAT 480AAGCAAATTG TGGATAAAGT GCGCGAAGAG TTAGGCATGG TTAAAAAG 528(2) SEQ ID NO 104 information

Sequence properties:

(A) length: 300 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...300

(xi) sequence representation: SEQ ID NO 104: CCCAAACCTT ACGCCGTCAG TATTCTATGT ATTTGCGTTA TGTTTATACT TTTTAAGTTT 60GGTAGGGTTT TGGGTAAGGC TTATAGCTTA TACTTATATA TATATGAAAG CTTGATTTGT 120CAAGCTTTTG GGTTGTCATT GAGTTGCAAT AACTCTATGC TGTTTTCTAC TTTTTTGATA 180AATCTACCAT TACCACACAA TGAGTCCTTA TGCTGTTGTA GGGATATTTT AGCGTATTCT 240AACTCTTCAT CGCTAAAGAC ATATTCATTG GAGTCAAATT TTTCTTTCAA TTCTTTATTT 300(2) SEQ ID NO 105 information

Sequence properties:

(A) length: 300 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...300

(xi) sequence representation:SEQ ID NO 105: ACAGCAAGAA TGAATCGCAT GAAACCAATT TTTTTGTTAA TCTTTTTGTT GTTAGCGAGC 60CTTATTGCTA GAGAAAAGGA CGCTTCTTCA AACCTTTTTG ATTTGATCGA TAAGGGGATT 120AACAGAGAAC AAGAATTGAA AGAGCAGGAG CAAAAAACGC GCTTGAAACT GGCTCAAAGC 180CCTTTAGTGG CGTTAGAAAT TGTCCCCCAA GAAACGCCCT ATTTAGAATG GCAAGGGGCT 240AGGGAGTCGT ATTATTTGAA AGTAGAGCGC TGTAGTGGAG AGCGTGGTTA TTTTAAAGAT 300(2) SEQ ID NO 106 information

Sequence properties:

(A) length: 693 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...693

(xi) sequence representation: 106: GTTGCTCGCG CTTTTATCGC TCTTTATGCC ATTTCAGCGG TCAATAAATC CAAAGTGGAA 60GCCTTAAAAA CCGAATTTAT TAAGATTTTT AATTACGCCC CAAAGCCAGA GGCGATGCAG 120CCGGTTGTAG TGATCCCCCC TGATTCAGGG AAAGAAGAAG AGCAAATGGC GAGCGAAAGC 180TCCAAGCCGG CTTCGCAAAA TACCGAAACA AAAGCCACTA TCGCTCGCAA GGGCGAAGGC 240AGTGTTTTAG AGCAAATTGA TCAAGGCTCT GTTTTAAAGC TCCCCTCTAG TTTGCTGTTT 300GAAAACGCCA CTTCAGACGC TATCAATCAA GACATGATGC TTTATATTGA ACGGATCGCT 360AAAATCATTC AAAAACTCCC TAAAAGGGTG CATATTAATG TGAGAGGTTT TACGGATAAC 420ACGCCTTTAA ATAAAACCCG TTTTAAAAGC CACTATGAAT TAGCCGCCAA TCGCGCTTAT 480AGGGTGATGA AAGTCCTTAT ACAATACGGC GTGGATCCTA ACCAATTGTC TTTTTCTTCT 540TACGGCTCTA CCAACCCTAT TGCGCCCAAT GATTCCCTAG AAAACAGAAT GAAAAACAAT 600CGTGTGGAAA TCTTTTTTTC AACCGATGCG AACGATTTGAGCAAGATCCA TTCTATTTTA 660GATGAAGAAT TCAATCCCCA TAAACAGCAA GAA 693(2) SEQ ID NO 107 information

Sequence properties:

(A) length: 294 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...294

(xi) sequence representation: SEQ ID NO 107: CAGCGTCTAT ACCTAGGAAA ATTAAACGCT AAAGTGAATC ACACGATTTT CCAATTTTTA 60GTGAATGTGG GCATTAGAAC CAATATTTTT GAACACCATG GCATTGAGTT TGGTATCAAA 120ATCCCCACGC TCCCTAATTA CTTTTTCAAA GGTTCTACTA CTATAAGAGC GAAAAAACAA 180GGCCCACTAG AGAATGGGAA CCCGACTACT ATCACCGGAG CAGAAACCAA TTTCAGCTTA 240ACCCAAACCT TACGCCGTCA GTATTCTATG TATTTGCGTT ATGTTTATAC TTTT 294(2) SEQ ID NO 108 information

Sequence properties:

(A) length: 1071 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1071

(xi) sequence representation: SEQ ID NO 108: TTTCATTTTT ACTGCTTGTA TTTCCTTAAT GGTGGTTATA ATCGGCTTCA TAAATCATAC 60GAAAGGATTG TCATGCTAAT CGCTCGCTTT AAAAAAGCTT TAATTTCCTA TTCTTTAGGG 120GTTCTTCTTG TTTCATCGTT ATTAGGCGTG GCTAACGCTT CTAATCAAGA GATCCAAGTC 180AAGGATTATT TTGGGGAGCA AACCATAAAG CTTCCTGTTT CTAAAATAAT CTACTTGGGC 240AGCTTTGCAG AAGTGCCTGC CATGTTCAAT ACTTGGGATA GGGTCGTGGG CATTTCGGAT 300TACGCTTTTA AATCTGATAT TGTTAAAGCC ACTCTCAAAG ATCTTGAACG CATTAAACCC 360ATGAGCAGTG ATCATGTGGC GGCGTTGAAT GTGGAATTAT TAAAAAAGCT TAGCCCTAAT 420CTTGTGGTAA CCTTTGTGGG TAACCCTAAA GCGGTAGAGC ATGCGAAAAA ATTTGGGATT 480TCATTCCTTT CTTTCCAAGA AAAAACCATT GTAGAGGTCA TGGAAGATAT TGACGCTCAA 540GCTAAGGCCT TAGAAGTTGA CGCTTCTAAA AAATTGGCTA AAATGCAAGA AACTTTGGAT 600TTTATCAAAG AGCGTTTGAA AAATGTCAAA AAGAAAAAGG GGGTGGAGCT TTTCCATAAA 660GCCAATAAAA TCAGCGGCCA TCAAGCCCTT GATTCAGACA TTTTAGAAAA AGGGGGTATA 720GATAATTTTG GCTTGAAATA CGTTAAGTTT GGACGCGCTG ACATTAGTGT GGAAAAAATC 780GTTAAAGAAA ACCCTGAAAT CATTTTCATT TGGTGGGTAA GCCCACTCAC TCCTGAAGAC 840GTGTTGAACA ACCCTAAATT TTCCACTATC AAAGCCATTA AAAACAAGCA AGTCTATAAG 900CTCCCCACAA TGGATATTGG CGGACCTAGA GCCCCACTCA TTAGTCTTTT TATCGCTTTA 960AAAGCCCACC CTGAAGCGTT TAAGGGCGTG GATATTAATG CGATAATCAA AGATTACTAT 1020AAAGTGGTCT TTGATTTGAA TGACGCGGAA GTTGAACCCT TTTTGTGGCA C1071 (2) SEQ ID NO 109 information

Sequence properties:

(A) length: 183 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...183

(xi) sequence representation: SEQ ID NO 109: GATCATCACA AGGAGTTTCG TATGAAAAAG CAAATCTTGA CAGGTGTTTT GTTATCAGTT 60TTGGCAGTGA GTTCTGCATA CGCTCACAAA GATAAAAAAG ACGCTAAAAA ACCTGAGTTA 120AGCTCTCAAT TAGTGGCTCA CAAAGATAAA AAAGACGCCA AAAAACCTAA AAACTCAGTG 180GCC 183(2) SEQ ID NO 110 information

Sequence properties:

(A) length: 600 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...600

(xi) sequence representation: SEQ ID NO 110: AGAATAATAA AAGGAAACAT TATGAGCAGC GGGTTAATTT ACATTTCATT AGAAGTCTTG 60GTAGCGTGTT TGATCACCGC TCTAATCATG TATTATGTGA TGAAAAAGAT CTATTACGCT 120AGAGGGCAAG CCATTTTAAA AGGCGCTTCA GCCAAAGCTA AATTAATGGA ATTTCAAGCG 180AAATCTTTCG TGGAAGCTGA AGAAATGCGC ATGAAAAGCC AAGAATGCAA GTTGCAACAG 240CAATATGAAA ATAAGAATTT GCAACTCCAA ACCCATTTTG ATAAAAAAGA AGCGCATTTG 300AAGCATTTAG AAGCGCAGCA CAAAGAATTT GTAAGAGATG AAAAACGCTA TTTGGAAAAG 360GAAAAAAAAG AGCTTGAAAA AGAACGCCAA ATTTTAGAAC AAGAGAGGGA AAATTTTAAA 420AAACAGCGCG CCATTTGTAA AGAAGCTCAA GCCAAAGCGC TAGATGCGAT GCTCAATTAC 480ATGGCTTATA CCAAAGATGA AATTAAAAGC ATGATCTTAG AGCAATTAGA ACAGGAACTA 540GAAGCGCAAA AGAGCGCCTT GATCAGGCGT TATGAAGAAG AAGCCTTTAT TATGTGTTTA 600(2) information 111 SEQ ID NO

Sequence properties:

(A) length: 501 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...501

(xi) sequence representation: SEQ ID NO 111: GGCCGAGCTT TTATGATGCG AGAGATCCTT ACTAACCGCT TTTTCCCAAG CCTTTTTAAA 60AAAAGGCTTG ATTTTTCTAA CAGAGTGGTT TTAGGGCTGG GATCTAATCT TAAAAACCCT 120TTAAAAATAT TAAAAAGTTG TTTTTTATAT TTTAAAAATC ATAGTAAAAT CGGGAAAATT 180TTTTCTTCAC CCATTTATAT CAATCCGCCT TTTGGTTACA CTAATCAACC TAACTTTTAT 240AACGCTACGA TTATCCTTAA AACATCTTTA GGTTTGCGCC ATTTTTTTGC TCTAGTGTTT 300TATATAGAAA GGCGTTTTGG GCGTGCAAGG AAGCGCGATT TTAAAGATGC TCCAAGAACT 360TTAGATATTG ATATTATCGC TTTCAATCAA GTCATTTTGA GGCAGAATGA TTTGACTTTA 420CCTCACCCTA AATGGAGTGA AAGAGACTCG GTGTTAGTGC CTTTAACTTT ACAACAAATC 480CTTTTTAAAA GAGAAGAGTG G501 (2) SEQ ID NO 112 information

Sequence properties:

(A) length: 513 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...513

(xi) sequence representation: SEQ ID NO 112: ATAATAGAAA TTTTAGTGAT TCAAGGGCCT AATTTAAACA TGTTAGGACA CAGAGACCCA 60AGACTTTATG GCATGGTAAC CTTAGACCAA ATCCATGAAA TCATGCAAAC TTTCGTGAAG 120CAAGGCAATT TAGATGTGGA ATTAGAGTTT TTTCAAACCA ATTTTGAGGG CGAAATCATT 180GATAAAATCC AAGAGAGCGT GGGCAGCGAT TATGAGGGGA TTATCATTAA CCCTGGAGCG 240TTTTCGCACA CTTCTATTGC GATTGCGGAT GCGATCATGC TAGCGGGCAA ACCTGTCATT 300GAAGTGCATC TCACTAACAT TCAAGCCAGA GAAGAATTCA GGAAAAATTC TTACACCGGA 360GCGGCTTGTG GAGGCGTGAT CATGGGATTT GGCCCGCTTG GCTACAACAT GGCTTTAATG 420GCGATGGTCA ATATTTTAGC CGAAATGAAA GCGTTCCAAG AAGCCCAAAA AAACAACCCT 480AATAACCCCA ATAACCCGAT CAACAATCAA AAA 513(2) information SEQ ID NO 113

Sequence properties:

(A) length: 198 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...198

(xi) sequence representation: SEQ ID NO 113: CCGCGAATCA TAGCATTCTT TTGGATATGG GGATCAAATA CGAACGCTAT TGCTCTGATA 60GGACTCGCAC GGCTTTTTTT GAACCCTAAA GACTTTGTGT TCAAAAGGGA GCAGAGTTTC 120AAGGATAAAG AGCGTCAAAA GATTTATGAC ATTGTGAAAG AAGCGCAAGA AAAGGCTATT 180CAGGCATTAG AGCGGGGA 198(2) SEQ ID NO 114 info

Sequence properties:

(A) length: 210 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...210

(xi) sequence representation: SEQ ID NO 114: CGATTATGGC TATGGGCAGT ATTCACTCAC AGCACCGGGC ATGGCATTGA CTTAGACATT 60CATGAGCTTC CCTATATTTC ATCGCGCAGT GAAACCATTT TAGAAGAGGG CATGGTGTTT 120TCTGTAGAGC CTGGGATTTA TATCCCTGGG TTTTTTGGGG TGCGCATTGA GGATTTAGTG 180GTGATTAAAA ATTCTAGGGC CGAGCTTTTA 210(2) SEQ ID NO 115 information

Sequence properties:

(A) length: 297 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...297

(xi) sequence representation: SEQ ID NO 115: TACCAATACA TCCAACAAGG CGGGGGCTTT GGGGTGAATG TCGGGCGCAC GCTGGGTAAT 60AGAACCCATG TGAGCTTAGG GTATAACCTG AATGTTACCA AACTCCTTGG TTTCAGCAGC 120CCCTTATACA ACCGCTACTA TTCCTCTGTT AATGAAGTGG CCTCTCCAAG GCAATGTTCC 180ACACCCGCAT CGGTGATTAT CAACCGCTTA TCAGGCGGTA GAACTCCATT GGTTCCTGAA 240AGCTGTTCTA GTCCTGGAGC GATCACCATC TTCACCAGAA ATAAAAGGTA TTTGGGA 297(2) SEQ ID NO 116 information

Sequence properties:

(A) length: 276 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...276

(xi) sequence representation: SEQ ID NO 116: ATGGCGTGTG AATTTTTGAA AAAGCCAAAG TATTACAAGT TTATAGAGGG GGCGAATTAT 60TTGAGCTTAG GGCTTTCTAT GGTGGTGGCG ATCCTTATGG GCGTGGCTAT AGGCTATGGG 120CTTAAAAAAC TCACTCACAT TTCGTGGCTT TTTTGGCTTG GGGTTATTTG GGGCGTGTTA 180GCGAGCTTTC TCAATGTCTA TAAGGCTTAT AAAAACATGC AAAAAGACTA TGAAGAACTA 240GCCAAAGACC CTAAATACAC GCAAAATAAA ACAAAA 276(2) SEQ ID NO 117 information

Sequence properties:

(A) length: 267 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...267

(xi) sequence representation: SEQ ID NO 117: AGGAACTTGA TGAAAACGAC AGAAAACACA GATGAAACTC ACTTAAGGGA AACTAAAAAT 60AAACTAGGAC GCAAACCAAA AGCAGACGCT AATAAAAAAA CTCGCGCGGT AAGCTTGTAT 120TTTTCTGATG AGCAATACCA AAAACTAGAG AAAATGGCTA ACGAAGAAGA AGAAAGCGTG 180GGATCTTATA TCAAACGCTA TATTTTGAAG GCTTTAAGAA AAATAGAACA AGGTGGTGGC 240TTTATAGCTT TTAACTTGTT TTTAATT 267(2) information of SEQ ID NO 118

Sequence properties:

(A) length: 309 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...309

(xi) sequence representation: SEQ ID NO 118: ATTTTGAAGG GGGGGTTTTT AGGGTTTTTT ATCGTGGCGT TGTCTTCGTA TTACGGCGTT 60AAAAAGCGTT TGGATTTGAG GAAACAAGAT TCAAAAGAAA AAGAAGAAAA GCAAAAATTC 120CAAAAATTCG CCCTAGGTTT GGAAATGTCT TTCAATGTGT GGCGTTTAGG GGGGTATGGG 180GTTTTATTAG GTATTTTAGG AGTGCTTTTA TTCTTGCATC TTTTTAACGG ATTGCCGTTT 240CTTATCGGCG TGTTTGTGAG CTCGCTCTCT AGCGCGTTAT TACGATTCTT AAACAATAAT 300GGTAAGTTT 309(2) SEQ ID NO 119 information

Sequence properties:

(A) length: 771 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...771

(xi) sequence representation: SEQ ID NO 119: GCCCTTACAC CAAATCCCAT GAAACTCCCG GTCGTTGAGA GCTTTTTTTC CTTACAGGGT 60GAAGGAAAAA GGATAGGCAA GCCCAGTCTT TTTTTGCGCT TAGGGGGGTG TAACCTTTCA 120TGCAAGGGCT TTAATTGTAA AACCTTATTC AATGATGAAA TCCTAACAGG TTGCGATAGT 180TTGTATGCGG TGCATCCTAA ATTCAAAACA TCTTGGGATT ATTACAATGA GCCTAAGCCC 240TTGATTGAAC GATTAGTTAA TTTAGCCCCT AATTATAAGG ATTTTGATTT CATTCTTACA 300GGCGGGGAGC CAAGCTTGTA TTTTAATAAC CCTATTTTAT TGAGCGTTTT AGAGCATTTT 360TACCATAAAA AAATCCCTTT ATTTGTAGAG AGTAATGGCT CTATTTTTTT TGAATTTAGC 420CCTATTTTAA AAGAATTGCA TTTCACCCTA AGCGTCAAAC TCTCTTTTTC TTTGGAGCAA 480GAAAGCAAGC GGATCAACCT TAAAGCCTTA CAAAATATCT TAAATAACGC TAAAAGCGTG 540CATTTTAAAT TCGTATTGGA GAGTCAAAAC GCCGCTCATT CTATCGCAGA AATTCAAAGC 600CTTTTGAAAC AGCTCTCCTT AAAAAATAAT GAAATCTTTT TAATGCCCCT AGGCACAACT 660AACAACGAGC TAGACAAAAA TCTAAAAACC CTAGCCCCCC TAGCCATAGA GCATGGTTTT 720AGGCTGAGCG ATAGGCTTCA TATCCGCTTG TGGGACAATA AGAAAGGGTT T771 (2) SEQ ID NO 120 information

Sequence properties:

(A) length: 1158 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1158

(xi) sequence representation: SEQ ID NO:120: TTCAAGGATC AAGGCATGAA TTTAAACTTT ATGCCCCTAT TGCATGCTTA TAACCATGTA 60AGCATTGATT TTCATTTCAA TTCTAGCGCT AGGGATTTTT GCGTGCATGA AGTGCCTTTG 120TATGAATTTA GCAACACGGG CGAACATGCC GTTATTCAAG TGAGAAAAAG CGGTTTAAGC 180ACTTTAGAAA TGCTTCAAAT TTTTTCTCAA ATTTTAGGGG TAAAAATCGC TGAATTGGGT 240TATGCGGGCT TGAAAGATAA AAACGCGCTG ACGACTCAAT TCATCTCACT CCCTAAAAAA 300TACGCCCCTT TATTAGAAAA AAATACGAGC AACTTTCAAG AAAGAAACCT TAAAATCCTG 360TCTTTGAATT ACCATCACAA TAAAATCAAA TTAGGGCATT TAAAGGGGAA TCGCTTTTTT 420ATGCGTTTCA AAAAAATGAC CCCCCTAAAC GCTCAAAAAA CGGAGCAAGT TTTAGAACAA 480ATCGCGCAGT TTGGCATGCC TAATTATTTT GGCTCGCAAC GCTTCGGGAA GTTCAATGAC 540AACCATAAAG AGGGGTTAAA AATCTTGCAA AATGAAACGA AATTCGCCCA CCAAAAATTA 600AACGCTTTTT TAATTTCAAG CTATCAAAGT TATTTGTTTA ATTCGCTTTT AAGCAAGCGA 660TTAGAAATCA GTAAAATCAT TAGCGCTTTT AGCGTCAAAG AAAGTTTAGA ATTTTTTAAA 720CAAAAAAATT TAAGCGTCCA TTCAAACGCC CTAAAAGCCC TTAAAAACCA AGCCCACCCC 780TTTAAAATCT TAGAAGGCGA TGTGATGCGC CATTACCCTT ATGGGAAGTT TTTTGACGCT 840TTGGAATTAG AAAAAGAGAG CGAAAGGTTT TTGAACAAAG AAGCTGTGCC TACGGGGTTA 900CTGGACGGTA AAAAAGCTCT TTATGCAAAA AATTTGAGTT TAGAAATTGA AAAAGGATTC 960CAGCATAACC TTTTAAGTGG CCATGCTAAA ACGCTAGGAT CCAGGCGGTT TTTTTGGGTG 1020TTTGTGGAAA ATATAACTTC TCAATACATC AAAGAAAAAG CGCAATTTGA ATTGGAATTT 1080TACTTGCCTA AAGGGAGTTA TGCGAGCGCG CTGCTCAAAG AAATCAAGCA TGAGAAAGGA 1140GAAAATAATG ACGAATTT 1158(2) SEQ ID NO:121 information.

Sequence properties:

(A) length: 189 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...189

(xi) sequence representation: SEQ ID NO 121: AAGATTAAAG GAAAAGAGAT GAAATTTTTA AACGGATTAG CAGGGAATTT ACTGATTGTG 60GTTATCTTAT TGTGTGTGGT CGTTTTTTTC GCGCTCAAAG CGATCCATAT CCAAAAAGAG 120CAAGCCACCA ATTATTACCG CTATAAGGAT ATTAACGCTT TAGAGGCAAA AAACACCCAA 180AACCACGCT 189(2) information SEQ ID NO 122

Sequence properties:

(A) length: 300 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D)Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...300

(xi) sequence representation: SEQ ID NO 122: ATGCTAGAAA TTGAATTAAA AAAGAAATTC ACTAAGGATT TAAAAAAGCA TATTTTAAAT 60CAAAAAATTG AGTTAGAAGT TTTTGACTTA GTGGTTGAAA ATTTAAGAAA TCAAATTCCA 120TTGGACAAAA GATTTAAAGA CCATGCTTTA AGTGGAACAT ACAAAGGCTG TAGAGAGCGC 180CACATTAAGC CTGATGTTTT GCTTGTGTAT AGAGTGAAAG GCAATGTTTT AACTTTGGTT 240AGGCTTGGCA GTCATAGCGA GCTGTTTTGT AAACCGCCCA CACCACTCAT AACGCTTAAA 300(2) SEQ ID NO 123 information

Sequence properties:

(A) length: 1938 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1938

(xi) sequence representation: 123: TCGAATTACA ACAACCTAAA CACTCTTGTA TCGCTGTCCT CCGATCCGAG TGCTGTCAAC 60GACGCAAGGG ATAATCTAGG CTCAAGCGCT AGGAATTTGC TAGATGTCAA AGCCAATTCC 120CCCGCCTATC AAGCGGTGCT TTTAGCATTG AACGCTGCAG TGGGCTTGTG GCAAGTTACA 180AGCTATGCCT TTACCGCTTG TGGTCCTGGT AGCAATGAGA ACGCGAATGG AGGTATCCAA 240ACCTTTAATA ATGTGCCAGG ACAAAACACG ACGACCATCA CTTGTAATTC GTATTATGAG 300CCAGGACATG GCGGGCCAAT ATCCACTGAA AATTATGCGA TCATCAACAA GGCTTATCAA 360ATCATTCAAA AGGCTTTGAC AGCCAATGGA GAAGGGATCC CAGTTTTAAG CAACACCACT 420ACAAAACTTG ATTTCACTAT CAATGGAGAC AAAAGAACGG GTGGCGAACC AAATAAAAAA 480TTAGTATACC CATGGAGTCA TGGGAAAGCT ATTTCAACCT CGTGGAATGC AACCATAACA 540GTACCAACAA CAGAAAATAT CAATACAACC AATAGCGCTC AAGAGCTTTT AAAACAAGCG 600AGCATCATTA TCACTACCCT GAATAGTGCA TGCCCAAACT TCCAAAATGG TGGTAGCGGT 660TATTGGGCAG GGATAAGTGG CAATGGGACA ATGTGTGGGA TGTTTAAGAA TGAAATCAGC 720GCTATCCAAG GCATGATCGC TAACGCGCAA GAAGCTGTCG CGCAAGCCAA AATCGTTAGT 780GAAAACACGC AAAATCAAAA CAGCCTAGAC GCTGGAAAAC CATTCAACCC CTACACAGAC 840GCTAGTTTTG CTGAAAGCAT GCTCAAAAAC GCGCAAGCCC AAGCGGAGAT TTTAAACCAA 900GCCGAACAAG TGGTGAAAAA CTTTGAAAAA ATCCCTACAG CCTTTGTAAA TGACTCTTTA 960GGGGTGTGTT ATGAAGTGCA AGGAGGTGAG CGTCGTGGCA CCAATCCGGG TCAGACGACT 1020TCTAACACTT GGGGGGCAGG CTGTGCGTAT GTAGGACAAA CGATAACAAA TCTTAAAAAC 1080AGCATCGCCC ATTTTGGCAC TCAAGAGCAG CAGATACAGC AAGCCGAAAA CATCGCTGAC 1140ACTCTGGTGA ATTTCAAATC TAGATACAGC GAATTGGGCA ACACTTATAA CAGCATCACC 1200ACTGCGCTCT CTAATATCCC TAACGCGCAA AGCTTGCAAA ATGCGGTGAG TAAAAAGAAT 1260AACCCCTATA GCCCGCAAGG CATAGACACC AATTACTACC TCAATCAAAA CTCTTACAAC 1320CAAATCCAAA CCATCAACCA AGAACTCGGG CGTAACCCCT TTAGGAAAGT GGGGATTGTT 1380AGTTCTCAAA CCAATAATGG CGCGATGAAT GGGATCGGTA TTCAGGTGGG TTACAAACAA 1440TTCTTTGGCC AAAAAAGAAA ATGGGGCGCT AGGTATTACG GCTTTTTTGA TTACAACCAT 1500GCGTTCATTA AATCCAGCTT CTTCAACTCG GCTTCTGACG TGTGGACTTA TGGCTTTGGA 1560GCGGACGCTC TTTATAATTT CATCAACGAT AAAGCCACCA ATTTCTTAGG CAAAAACAAC 1620AAGCTTTCTG TGGGGCTTTT TGGGGGTATT GCATTAGCCG GGACTTCATG GCTTAATTCT 1680GAGTATGTGA ATTTAGCCAC CATGAATAAC GTCTATAACG CTAAAATGAA CGTGGCGAAT 1740TTCCAATTCT TATTCAACAT GGGAGTGAGG ATGAATTTAG CCAGGCCTAA GAAAAAAGAC 1800AGCGATCATG CGGCTCAGCA TGGGATTGAG TTAGGGCTTA AAATCCCCAC CATCAACACG 1860AACTACTATT CCTTTATGGG GGCTGAACTC AAATACCGAA GGCTCTATAG CGTGTATTTG 1920AATTACGTGT TCGCTTAC 1938(2) SEQ ID NO 124 information

Sequence properties:

(A) length: 279 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...279

(xi) sequence representation: SEQ ID NO 124: GATTTAAAAA TGCTGACGAT TGAAACCAGT AAAAAATTTG ATAAGGATCT TAAAATTCTT 60GTTAAAAATG GGTTTGATTT AAAGCTTTTG TATAAAGTGG TTGGAAATTT AGCCACAGAG 120CAACCCCTAG AACCCAAATA CAAAGACCAC CCACTCAAAG GCGCTTTAAA AGACTTTAGG 180GAATGCCACC TAAAACCGGA TTTATTGCTT GTCTATCAAA TTAAAAAACA AGAAAACACT 240CTTTTTTTAG TAAGGCTAGG CAGTCATAGC GAGCTGTTT 279(2) SEQ ID NO 125 information

Sequence properties:

(A) length: 243 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...243

(xi) sequence representation: SEQ ID NO 125: CGCGCATGGA GAATGAAAAG CATGCGTTTT AGTTACATTG AGCCAAGAGC GAAATACTTA 60ATCAGCAAGC TTTCTAAAAT TTGGGTTTTT TACATTTTTT TATCTTTTGT GCTAATAGGG 120GGGTTAGTGT GGTTTATGCA CAACGCCATT AAACGCGCTC AAGACAACGC GTCTAGTCTG 180ACGATCCAAG AAGAGCTTTA CCGCTGTTAC ATCACCCGCT TGTCTGTTAA GATGATTATA 240CTC 243(2) SEQ ID NO 126 information

Sequence properties:

(A) length: 447 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...447

(xi) sequence representation: SEQ ID NO 126: GTTAAATTTC CTTATCTGTT AAACATACGG ATAATGTTAT ATCTAAGGAA AGAAAATGGG 60GTTAGGACAC TAATAAGTTT AGGGATTTTG TTAAGCGTTT TGAATGGCGA TGATCTGAGA 120TTGTATTCAA AACCTTTGGT CTATTCGGCT GGAAGTGGGA TTATTGGGAT TGATATTGAC 180AAACGGACAT TCTATAAACG AGCGTTCGCT TTCACGATGA AATCGTTGTT TGGTGAAAAC 240TTGCTTTTGT TTGTTAAATT GAAGCATTCT GCGTTGATGA GCAAACACAT GAAAGGGCCT 300TTAGAAAACC GCCACCACCA TTCTTTCGCT AAAAATTATG AAAAAGCGGT TAATGGTTGT 360CAAAAATATG TCCATATCAA ATTGCCTGAA GGGCCTCCTA GCAACTTCCA ATCAGGCTCA 420TACATGGCGA CTATGGTGAT GCGTTTT 447(2) SEQ ID NO 127 information

Sequence properties:

(A) length: 477 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...477

(xi) sequence representation: SEQ ID NO 127: GTCATCACCA ACCAACAAAA CGAAGTCAAA ACTTTCACGC CCATTGAAAC CAAAAAGATC 60ACTTCCAAAG AACAAGCTTT TTTAACCCTT TCAGCGCTGA TGGATGCGGT AGAAAACGGC 120ACAGGGAGTT TGGCTCGCAT TAAAGGTTTA GAAATTGCCG GTAAAACCGG AACTTCTAAC 180AACAATATTG ACGCTTGGTT CATTGGCTTT ACCCCCACCT TACAAAGCGT GATCTGGTTT 240GGGAGAGACG ATAACACGCC TATTGGCAAA GGAGCGACAG GAGGCGTTGT GAGCGCGCCT 300GTGTATTCGT ATTTCATGCG CAATATCTTA GCGATTGAAC CTTCTTTAAA AAGAAAGTTT 360GATGTCCCCA AAGGCTTGCG TAAAGAAATC GTGGATAAAA TCCCCTACTA CTCAAGCCCT 420AATTCCATCA CCCCCACCCC CAAAAAAACA GACGATAGCG AAGAACGCTT GTTGTTC 477(2) information SEQ ID NO 128

Sequence properties:

(A) length: 240 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...240

(xi) sequence representation: SEQ ID NO 128: TTATTGTTAA ATCTTAAGAT TTATGTTACA CTCTGTAAAA TCCAAGGGGA TAGCGTGTTA 60GAAAAATCTT TTTTAAAAAG CAAGCAATTG GTTTTATGCG GGTTGGGTGT TTTTATGTTG 120CAGGCTTTGC ACTTCGCCCA AACACTTCAC AAAGAAATTC TTTTTTACAA GATGTGCCTT 180ATTGGATGTT GCAAAATCGC AGCCAGTATC TCACGCAAGG GGTGGATAGC TCGCACATTG 240(2) information SEQ ID NO 129

Sequence properties:

(A) length: 1032 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1032

(xi) sequence representation: SEQ ID NO 129: GTCAAGTGTG GCAAAAAGGG GATTTTAGTT TCAACGCGCA AGGCAATGTT TTTGTGCAAA 60ATTCCACTTT CTCTAACGCT AATGGAGGCA CGCTCAGTTT TAACGCAGGA AATTCGCTCA 120TTTTTGCCGG AAACAACCAC ATCGCTTTCA CTAACCATTC TGGAACGCTC AATTTGTTGT 180CTAATCAAGT TTCTAACATT AACGTCACCA TGCTTAACGC AGCAACGGCC TAAGATTAAC 240GCCACTAATA ACAATGTTTC CGTGTCTCAA GGCAATCTGT TTATCAACGC TAGCTGCGTG 300CAACAAAGCG ATCCAACGAC AGCTAGCGCC ACAAACCCTT GCACCACCGC TCAAAATAAC 360GCTTCTTCTA GTAATGCGTC AAACAACGCG CCAATCGCCT TAAATAATAA CGATGAAAGC 420TTGGTGGTTA CGGCGAATGG TTTCAATTTT TCAGGCAATA TTTACGCTAA CGGGGTGGTT 480GATTTTTCAA AAATTAAAGG CTCTGCAAAC GTTAAAAACC TGTATCTTTA CAATAACGCT 540CAATTCCAAG CCAACAACCT CACGATTTCC AACCAAGCGG TATTAGAGAA AAACGCTAGC 600TTTGTAACGA ATAACTTAAA CATTCAAGGA GCGTTTAACA ACAACGCCAC GCAAAAAATA 660GAGGTGCTTC AAAATTTAGT GATCGCTTCA AACGCTTCTT TAAGCACCGG GATTTATGGG 720TTAGAAGTAG GGGGGGCATT GAATAATTTG GGAGCGATCC ATTTTAATTT AGAAAATTCT 780CAAACGCCTG TAAATCCGCT CATTCAAGTA GGGGGGATCA TTAATCTCAA CACCACCCAA 840ACGCCTTTTA TGAATGTCAG CGTGGCTAAT GGCGGAACTT ACACTTTATT AAAAAGCAGC 900CGTTATATTG ATTACAATAT CAACCCTAAC AGCTTGCAAT CGTATTTGAA GCTCTATACC 960TTAATCAATA TCAACGGAAA CCACATAGAG GAAAAAAACG GCGTATTGAC TTATTTGGGC 1020CAACGGGTTT TA 1032(2) SEQ ID NO 130 information

Sequence properties:

(A) length: 798 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...798

(xi) sequence representation: SEQ ID NO 130: TTGTTGGCGC GCACCATACT TGATTTTAGA GGCAGCCTTA GTAATTTAAA CAACACTTAT 60AACAGCATCA CCACGACCGC TTCAAACACG CCTAATTCCC CATTCCTTAA AAATTTGATA 120AGCCAATCCA CTAACCCTAA TAACCCCGGG GGCTTACAGG CCGTTTATCA AGTCAACCAA 180AGCGCTTATT CGCAATTATT AAGCGCCACG CAAGAATTAG GGCATAACCC TTTCAGACGC 240GTTGGATTAA TCAGCTCTCA AACCAACAAT GGTGCCATGA ATGGGATCGG TGTGCAAGTG 300GGCTACAAAC AATTTTTTGG TGAAAAGAGA AGGTGGGGGT TAAGGTATTA CGGCTTTTTT 360GACTATAACC ATGCTTATAT CAAATCTAGC TTTTTCAATT CGGCTTCTGA TGTGTTCACT 420TATGGGGTAG GGACAGATGT CCTCTATAAC TTTATCAATG ATAAAACCAC CAAAAACAGC 480AAGATTTCTT TTGGGGTGTT TGGGGGGATT GCGTTAGCTG GCACTTCATG GCTGAATTCC 540CAGTATGTGA ATTTAGCGAC CTTCAATAAT TTCTATAGCG CTAAAATGAA TGTGGCGAAT 600TTCCAATTCT TGTTCAATTT AGGCTTGAGA ATGAACCTCG CTAAGAATAA GAAAAAAGAC 660AGCGATCATG CGGCTCAGCA TGGCGTGGAA TTGGGCGTGA AAATCCCTAC CATTA ACACC 720AATTATTATT CTTTTCTAGG CACTAAGCTA GAATACAGAA GACTCTATAG CGTGTATCTC 780AATTATGTGT TTGCGTAT 798(2) SEQ ID NO 131 information

Sequence properties:

(A) length: 285 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...285

(xi) sequence representation: SEQ ID NO 131: CGCAACGTGG AAGCGCGTTA TTATTATGGG GACACTTCAT ACTTTTATTT GCATGCGGGA 60GTTTTACAAG AGTTCGCTCA CTTTGGATCG AATGATGTGG CGTCTTTAAA CACCTTTAAA 120ATCAATGCCG CTCGCAGTCC TTTAAGCACC TATGCAAGAG CGATGATGGG TGGGGAATTG 180CAATTGGCTA AAGAAGTGTT TTTGAATTTG GGCGTGGTTT ATTTGCACAA TTTGATTTCC 240AACGCAAGCC ATTTCGCTTC CAATTTAGGA ATGAGGTATA GTTTC 285(2) SEQ ID NO 132 information

Sequence properties:

(A) length: 465 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...465

(xi) sequence representation: SEQ ID NO 132: AGACTTCCTA AAAAAGAAGA TTACGCTAAG GCGATGGTGT TTTCTTTTAA AATGGAAGCC 60ATCAAAGAAA GCCAAATCGT TTTATTGATC ACTTCAGCGT TTGAGGGCCA ATTTGAAAAA 120ACGCATAAAG AAGAAAAAGA AGAAACGACA AAAAGCGCTA CTGAAGAGAC TAAAACCCAC 180GACGCGTCTT TAGAAAATAT AGAAATCCGC AATATCAGCA TGCTTTTAGA CGTGAAATTG 240AACGTTAAGG TGCGTATCGG TCAAAAAAAG ATGATTTTAA AAGATGTGGT CTCTATGGAT 300ATAGGGAGCG TGGTGGAGTT GGATCAATTG GTGAATGACC CTTTAGAAAT CCTCGTAGAT 360GACAAGGTGA TCGCTAAGGG CGAAGTGGTG ATCGTGGATG GGAATTTTGG CATTCAAATC 420ACGGATATTG GCACTAAAAA GGAACGATTA GAGCAACTGA AAAAT 465(2) SEQ ID NO 133 information

Sequence properties:

(A) length: 633 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...633

(xi) sequence representation: SEQ ID NO 133: AAACCTACCA ATGTTTGGGC TAACGCTATT GGGGGAGCGA GCTTGAATAG CGGCTCTAAC 60GCTTCATTGT ATGGCACAAG CGCCGGCGTA GACGCTTTCC TTAACGGGAA TGTGGAAGCC 120ATTGTGGGCG GTTTTGGAAG CTATGGTTAT AGCTCCTTTA GCAATCAAGC GAACTCTCTT 180AACTCTGGGG CCAATAACGC TAATTTTGGC GTGTATAGCC GTTTTTTTGC CAACCACCCT 240GAATTTGACT TTGAAGCTCA AGGGGCGCTA GGGAGCGATC AATCAAGCTT GAATTTCAAA 300AGCACTCTAT TACAAGATTT GAATCAAAGC TATAATTACT TAGCCTATAG CGCCACAGCA 360AGAGCGAGTT ATGGTTATGA CTTCGCGTTT TTTAGGAACG CTTTAGTGTT AAAACCAAGC 420GTGGGCGTGA GCTATAACCA TTTAGGTTCA ACCAACTTTA AAAGCAATAG CCAATCACAA 480GTGGCTTTAA AAAATGGCGC GAGCAGTCAG CATTTATTCA ACGCTAACGC AACGTGGAAG 540CGCGTTATTA TTATGGGGAC ACTTCATACT TTTATTTGCA TGCGGGAGTT TTACAAGAGT 600TCGCTCACTT TGGATCGAAT GATGTGGCGT CTT 633(2) information SEQ ID NO 134

Sequence properties:

(A) length: 1029 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1029

(xi) sequence representation: SEQ ID NO 134: CATGCTAGGG AATTTTGCCA AGTTGTGATG TTTCACAAAG CCCTTATTAC CTTTATCGTT 60CTATGGTTTT TTTTGAATGG CTTAGGGGCT TATGATTTCA AGCATTGTCA GGCTTTTTTT 120AAAAAAGCGA GCCTTCAAAA AGGGGGCGTG GCTTTAAAGG AATTGCCTAA GGGCGTGTAT 180TTGTATTATT CTAAAACCTA CCCCAAACAC GCTAAAGTCA TCAAATCCGA TCCTTTTATA 240GGGCTGTATT TGTTGCAAAG CGCGCCAAGC GAGTATGTTT ATACATTAAG GGATTTAGAC 300AAAGACGCCC TTATAAGACC CATGGCCAGT ATAGGGGCTA ATCAAGCCAC AGAAGCGCGA 360TTATTGGTAG GGCAAAAAGG CTATGACCGC TACGCTCAAA TTTCACAAAA AACCCAAAAA 420AATGGCGTTA TCAGCAATAT TTGTTATCAA ATGCTAGGGC TAGGGGTAGG GGGGAACGGC 480TTTATAGAAA CGAAATTCAT CAAGCGCTTT TTAAACCAAC AAGAGCCTTA TTATGGGGAT 540ATTGGGGTGC GTTTAGAAGA ACGTCATAAG CGTTTGGTGG TAGCGCAATT TGATCCCTTT 600TTCCCTAAAA ACCCTTTTTT AAAAAACGAT GAAATCCTAG CGATCAATGA TTACAAGATC 660CACTCGTTAG CGGAGTTTGA ATGGGTGGTG AGCAATCTTT CATACCAAAG CCTCGCCAAA 720GTGAAAATCA AACGAAACCA TCAAATCAAA GAAGTAACGC TCAAAGTCAA TAAACGCTAT 780GGGGGGTTTT TGCTCAAAGA CACTTTTTTA GAGCGCTATG GCATCGCTTT AGACGAGCGT 840TTTATCATCA CTAAAATAGG CGCTCATTTG CCCAAAGGCT TGGATTTTTT AAAGCTTGGG 900GATAGGATTT TATGGGTGAA TCATAGAAGC GTTTCGTTCA ACCCGAAAGC TTTAAGAGAA 960GCGTTAAGCA CGCCTAAAAT TGAATTATTA GTCTGGCGTC AAGGCTTTGA ATTTTACATT 1020AAAGTCCGT 1029(2) SEQ ID NO 135 information

(ii) sequence properties:

(A) length: 495 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...495

(xi) sequence representation: SEQ ID NO 135: ATTAAAATTA ACATGGTAGA ATGCCAAAAT TTGCTGTCGT CATGCGGCAA AAATTTAGAC 60AACAAGGAAT TGGGAATGAG AAGGAGTTTG GCTTTTTGCC TTTTAGCTTT GCTTGGATTA 120CAGGTTTTAG GTGCTAGAGA CTTTTCGCAA CTCAAAAACG AAGAACTTTT AAAATTAGCA 180GGAACTCTGC CTTCTAATGA AGCGATTGAT TATCGCATGG AAGTGTCTAA ACGCCTTATA 240GCCTTAAGTG CTGAAGACGC TAAGAATTTC CGCGCGAATT TCAGCCGGAT CGCTAGGAAG 300AATCTTTCTA AAATGAGCGA AGAGGATTTC AAAAAAATGC GTGAAGAAGT GCGTAAAGAA 360TTAGAAGAAA AAACCAAAGG TCTAAGCGCT GAAGAAATCA AGGCAAAAGG ACTTAATGTG 420AGCGTTTGCA GCGGCGATAC GAGAAAAGTT TGGTGTAGGG CTGTTAAGAA AAAAGACGAA 480CATTGCTCTC CTAAG 495(2) SEQ ID NO 136 information

Sequence properties:

(A) length: 471 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...471

(xi) sequence representation: SEQ ID NO 136: TTTAAAAGGA AAAACATGAA AAAAGCGTTG AAAATACTTT CTGTTGGCGC GTTGCTATTT 60GTGGCTTTAA ACGCCAAAGA TTTCAGCAAA ACAAGCGATG AAGATTTGGC TAAAATGGCT 120GGCGTTGTCG CTCCGCAGGA TATTGTGGAT TACACAAAAG AGTTGAAAAA GCGCATGGAA 180AAGATGCCTG AAGACAAGAG AAAGGCGTTC CATAAACAAT TGCATGAATA CGCGACTAAA 240AACACAGACA AAATGACCGT GGCGGATTTT GAAGCCCGCC AAAAAGCCAT TAAAGAAGCG 300CTTAAAAAAG GCAATATGGA AGACATGGAT GATGATTTTG GGTTGAGATC ATGCAAGCAT 360GGGAAAAAGC ACAAACACGA TAAGCATGGC AAGAAGCATG GCAAAAAACA TGACAAAGAT 420CATGACGATA AAGACCATGA CCACCATGAT GAAGATCACA GCGATAAGCA C471 (2) SEQ ID NO 137 information

Sequence properties:

(A) length: 2031 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2031

(xi) sequence representation: SEQ ID NO 137: ATCCAAAGAT ATTGGAATGG AGCGTTAATG AAAAATCAAC ACAAAAATCC CCTAACAAAA 60GCTTTAATGA AAACTTATCC ATATAACCAT TTTTTATTTT TCTGCTTTAT TCTAGGAGCG 120TTTTTATTAG GTTTGCTCAG TCCAGCTTAT GCTTTAAGTA TTATCACCAC TAAAGAAATT 180GACGCTAATT TGCTTAATGG AGCGATAGAA AGCAGGGTGG TGTTAGGCAA GAGGGTGTTT 240AAAGTAGAAG CTCATGGGTT TTATTTTAGA AACAATGCGA CTAACAGCAT AGATATAGAA 300ATCACCAGTC TTTTAAGAGA CAATCAATCG TTTCCTTTGA CTAGCAGTGC TAAAACCAGT 360TTAAAAATAC CTCCTAACGC CAAGATTAAA AAATCCACTA TCCTTGTTTT GAAAGGCGAG 420AACGCTGAAG AAGTGGCTAA GATTTTAGGC GTTAGCAAAG AAGAATACCA AAAGCTAGAA 480AACATCGCTC AAACCAAAGC GGCTAATGAC CCTATGTATG CTAACACGCC TTTTAGTAAT 540GGTTCTGATA GTTCCTTTTA CGATAACAAT CCTAATAGCC CTAGCAATAA CGCTATCAAT 600GGCAAAGATG GCGCAAATGG GAGTAACGGC TATGGGGCAA ATGGCAATGA TGGGGTAAAT 660GGGATCAGTG GGAGTAATGG TGCAAATGGG AGTCATTCAA ATAATAATGC AATAGGCAGT 720GGTATTGATA CAGATGGCGT GTTAGGGGTG GATGGGGTGA ATGGCTCTAG TTCTTCAAGT 780GGCGGCTCTG TAGGGGGTTA TGAGAATAAT TTCACTAATC ATGGCTCTAC TAACAATAAC 840ACAGGAGGGT ATGACAATTT TAATAATGGC AGCTCAAGTG GTGGGAGTTT AGGGAATGGG 900GGGCTTTTCC CTATTCCTTT TGGTAATGGA GACACAAACA ATTCCAATAA TTCCACTAAC 960ACCACTAGCC CAACTAATGG CAGTAGTTCT AATAACGCCA CTAATCCTAG TTCGCAAGAA 1020AACAATTACT CCAGCCAGTA TTGTAAAGTG CCAGAGTTAA GCCCCAACAA CACGATGAAA 1080CTAGATGTTA TCGCTAAAGA TGGCTCTTGT ATTTCTATGA ACGCTTTAAG AGATGACACT 1140AAATGCGCTT ATAGATACGA TTTTGAAGCC GGTAAAGCCA TCAAGCAAAC GCAATACTAC 1200TATGTAGATA GGGAAAATAA AACGCAAAAT ATCGGTGGTT GTGTGGATTT ACAAGGCGCT 1260CAATACGCCA TGCAACTTTA CAAAGATGAC AGCAAATGCG CCTTACAAAC CACGAGCGAT 1320AAAGGTTATG GTATGGGGAA AACGCAAACC TTTCAAACTG AAATCGTGTT TCGTGGGATG 1380GACAATTTAA TCCATGTCGC TGTGCCTTGC AGCGATTATG CAAGGGTGCA AGACAGGATT 1440GTTAGGTATG AAAAAAATGA TAAAACCCAA ACCTTAACGC CTATAGTGGA TCAGTATTAT 1500AATGATCCTA ACAACCCTAA CAAGCAAGAG ATTTTAAATC GTGGGATTGC CACCCAATTA 1560AGCTCGCAAT ATCAAGAATT TGCATGCGGT CAATGGGAAT ACAATGACGC TAAATTAGAA 1620GCCAAAAGAC CTACAATGCT AAAAAGCTAT AACAAGCTTA ATGGAGAATG GGTAGAAGTT 1680ACGCCCTGTA ATTTTGAAGC AGGGATTAAA AGCGGTGCGG TTGTTAGCCC TTATGTGATG 1740GGCGTGCCTA GTTCTAAAGT CTTAAGCGAT ATTACTACAA GCCATTATTT TAGGATAGAA 1800AGGAAAAATT ATGGTGAGAG AGAACAATGC CAAAAACTTT ATGGAGTCAA TCGTTGCCAA 1860CCGCAATATT CCATACTGAT CCTAGTATCA CCGATTGGAG CGCCACTTAC AAAACCACTA 1920CCACCCAAAC CACTCAACCT TATTTACGCC CAGCCCAAGA TAATGAAAAA CACCCCACAA 1980CCTATAATCT TATCACCACT CAAACCACCA TCAACAGGAC TCAAAGCGTT T2031 (2) SEQ ID NO 138 information

Sequence properties:

(A) length: 339 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...339

(xi) sequence representation: SEQ ID NO 138: ATGGCTAAAA TGAACGCTCC AGATGGGGTT GCCGTTTGGG TGAATGAAGA CAGGTGTAAG 60GGTTGTGATA TTTGCGTGTC GGTATGCCCG GCTGGAGTTC TTGGCATGGG GATTGAAAAA 120GAAAGGGTGC TTGGAAAAGT GGCCAAAGTA GCCTATCCAG AGAGCTGTAT TGGTTGCGTG 180CAATGCGAGT TGCACTGCCC GGATTTTGCG ATTTACGTGG CTGACAGGAA GGATTTCAAA 240TTCGCTAAAG TTTCTAAAGA AGCCCAAGAA AGAAGCGAAA AGGTTAAGGC CAATAAATAC 300ATGCTCTTAG AAGAGACTAT TTTAGAAGGG AGAGGCAAA 339(2) SEQ ID NO 139 information

Sequence properties:

(A) length: 987 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...987

(xi) sequence representation: SEQ ID NO 139: ATGACGACTA AAAGAGTGAA TACTGCCACA AACAAGATAA TGACATTAAA CACTTTCTTG 60GATACATGTT TTCTTTTCTT CATCAGTATT CTTTTTTACC TAAGTATACC AATTTATCCT 120AACAAAGTGG TGGTTGTCCC GCAAGGTTCG CTCAAAAAAG TGTTTTTTTC TTTGAAAGAG 180CAAGGCGTGG ATATTAACGC TTTAGATTTG CTTTTGTTGC GCCTAATGGG CATGCCTAAA 240AAAGGCTATA TTGACATGGG CGATGGGGCT TTAAGGAAGG GGGATTTTTT AGTCCGTTTG 300ATCAAAGCGA AAACGGCGCA AAAAAGCGTT ACTTTAATCC CTGGAGAAAC CCGCTATTTT 360TTCACGCAAA TTTTGAGCGA GACTTACCAA CTAGAAACAA GCGATCTCAA TGAAGCTTAT 420GAAAGCATCG CTCCACGATT AAACGGCGCT GTGATAGAAG ATGGGGTGAT ATGGCCAGAC 480ACTTATCATT TACCTTTAGG GGAGGACGCT TTTAAAATCA TGCAAACTTT GATTGGTCAA 540TCCATGAAAA AACACGAAGC CTTAAGCAAA CAATGGCTTG GATACTACCA TAAAGAAGAG 600TGGTTTGAAA AAATCATTCT CGCTTCCATT GTGCAAAAAG AAGCCGCTAA TGTTGAAGAA 660ATGCCCCTGA TTGCGAGCGT GATTTTTAAC CGCTTGAAAA AAGGCATGCC TTTACAAATG 720GATGGGGCTT TGAATTATCA GGAATTTTCA CACGCTAAAG TAACCAAAGA GCGCATTAAA 780ACCGATAACA CCCCCTACAA TACCTATAAA TTTAAGGGCT TGCCTAAAAA TCCTGTAGGG 840AGCGTGAGCT TAGAAGCGGT TAGAGCCGTG GTTTTCCCTA AAAAAACGGA TTTCTTGTAT 900TTTGTGAAAA TGCCGGATAA AAAACATGCT TTCAGCGCAA CTTATAAGGA GCATTTAAAA 960AACATTAATA TTTCTAATAA TCATTTT 987(2) SEQ ID NO 140 information

Sequence properties:

(A) length: 444 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...444

(xi) sequence representation: SEQ ID NO 140: AAATTCATGA GATTGTTGTT CTTGTTACTG AGCGCTACTT TGATGTTACT GGCTGAAGAA 60AAAATACCTT TAAGCGATGA CGCCCCCATT AAATTGGTTC ATTGGCAAAA TGCGCTAAAA 120GAAGTCCAAC CCGATTCAAA CGCTCCGGCA ACGCCACCTA TAAAGGCCGT GCAAACCACG 180CTCACTTTTG AAACGCCTTT TAATAAAACG CCTAAAATCA TGGAGGTTGA AGGGCAAAAA 240GTCATCGTGT TAAAAAACGC TCAATTGGAT TCTAAAAAAA CGATGGATTT TAAAGAAGCC 300TCTTTGAATG CCTTAGAAAT GTTTTCCTAC CAAAATGACA TCTACCTCTT GTCTAAAAAA 360GCTAAAGCGG GATTAGAAAT CCAAGCTTCA AGCAGCAAGG ATAAAAAGCA ACTCGCTTTC 420TTTTTTTACC CAAAGGTTTT CATT 444(2) SEQ ID NO 141 information

Sequence properties:

(A) length: 783 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ fefature

(B) Position: 1...783

(xi) sequence representation: 141: GAATTGATTT TAAAGAAAAA GAAAGAAAGG AATTTAATGA AAAAAGGTAG TTTAGCAATC 60GTTTTAGGAT CGTTACTAGC AAGTGGGACG TTTTATACGG CTCTAGCTGA TGGAATGCCT 120ATGAAGCAAC AGCACAATAA CATGGGTGAG TCTGTGGAGT TGCATTTCCA CTATCCTATT 180AAAGGCAAAC AAGAGCCTAA AAATAACCAT TTAGTTGTCT TAATCGATCC TAAGATAGAG 240GCTAATAAAG TTATCCCTGA AAATTATCAA AAAGAATTTG AGAAGTCTTT GTTCCTCCAA 300CTGAGTAATT TTTTAGAGAG AAAGGGCTAT AGCGTTTCGC AATTTAAAGA TGTTAGCGAA 360ATCCCTCAAG ACATCAAAGA AAAAGCGTTG CTCGTTTTAC GCATGGATGG GAATGTGGCT 420ATCTTGGAAG ATATTGTAGA AGAGAGCGAT GCGCTCAGTG AAGAAAAAGT GATAGACATG 480TCTTCAGGGT ATTTGAATCT GAATTTTGTT GAGCCAAAAA GTGAAGACAT TATCCATAGT 540TTTGGTATTG ATGTTTCAAA GATTAAGGCT GTGATTGAAA GGGTGGAATT GCGGCGTACC 600AATTCTGGAG GTTTTGTCCC CAAAACTTTT GTGCATAGGA TCAAGGAAAC CGACCATGAC 660AGAGCCATTA AAAAGATCAT GAATCAAGCC TATCACAAAG TGATGGCGCA TATCACCAAA 720GAATTAAGCA AAAAACACAT GGAACGTTAT GAAAAAGTTT CTAGTGAAAT GAAAAAGCGA 780AAG 783(2) SEQ ID NO 142 information

Sequence properties:

(A) length: 804 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...804

(xi) sequence representation: SEQ ID NO 142: GACCAAAAAT TCAAGGGGAT TATTTTAGCT ATGAAAATCA GTGTTAGTAA AAACGATTTA 60GAAAACACTT TGCGCTACTT GCAAGCTTTT TTGGATAAAA AGGACGCTTC CTCTATCGCT 120TCACACATCC ATTTAGAAGT CATTAAAGAA AAGCTCTTTT TAAAAGCCAG CGATTCAGAT 180ATTGGACTAA AAAGCTATAT TTCTACGCAA TCTACCGATA AAGAGGGCGT AGGCACGATC 240AACGGGAAGA AGTTTTTAGA TATTATCTCA TGTTTGAAAG ACTCTAATAT TGTTTTAGAG 300ACTAAAGATG ACAGCTTGGT GATCAAACAA AATAAAAGCT CTTTCAAACT CCCCATGTTT 360GACGCTGATG AGTTCCCTGA ATTCCCTGTT ATTGATCCAA AAGTGAGTTT AGAAATCAAT 420GCCCCCTTTT TGGTGGATGC GTTTAAAAAG ATCGCTCCTG TGATTGAGCA AACTAGCCAT 480AAAAGGGAAT TAGCCGGTGT TTTAATGCAA TTCAATCAAA AACACCAAAC CCTTTCAGTG 540GTAGGCACGG ATACCAAGCG GCTCTCTTAC ACGCAGTTAG AAAAAATCTC TATCCATTCC 600ACCGAAGAAG ACATCTCTTG CATTTTGCCT AAAAGGGCTT TATTGGAAAT CCTTAAACTT 660TTTTATGAAA ATTTCAGTTT TAAAAGCGAC GGCATGTTAG CGGTGGTTGA AAACGAAACG 720CACGCTTTTT TCACCAAGCT CATTGATGGG AATTACCCTG ATTATCAAAA AATCCTCCCT 780AAAGAATACA CTTCTCTCTC ACTT 804(2) SEQ ID NO 143 information

Sequence properties:

(A) length: 1248 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type ofmolecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1248

(xi) sequence representation: SEQ ID NO 143: AACCCATTGA TTCAAAAGAA CAAGAGCTTA TCAATCTTTT TAATCTCAAA TTCGGTCGTT 60TTTCTTGGGA AAATTATCTT GCATAAAGTT TTTATCATGG AAGCTTTGGA GTGTTTGAAA 120AGAATAGAAA AAGAAAGCAT CCAAACAATC TATATAGACC CCCCTTATAA CACCAAGAGT 180TCTAACTTTG AATATGAAGA CGCTCATGCT GACTATGAAA AATGGATTGA AGAACATTTG 240ATTTTAGCAA AAGCTGTGTT AAAACAAAGT GGTTGTATTT TTATTTCTAT GGACGATAAT 300AAAATGGCTG AAGTTAAAAT CATTGCCAAT GAAATTTTTG GAACGCGCAA TTTTTTAGGC 360ACTTTTATCA CCAAACAAGC CACAAGATCT AACGCTAAAC ACATCAATAT TACTCATGAA 420TATGTTTTAA GCTACGCTAA AAATAAAGCG TTCGCTCCTG GTTTTAAAAT CTTACGAACG 480CTTTTGCCCA TTTATGCTAA AGCATTAAAA GATTTAATGC GAACGATTAA GAATGTTTTT 540AAACAAAAAG GACAAGCTCA AGCCCAACTT ATTTTAAAAG AACAAATCAA AGAGTTATCC 600CAAAAAGAAC ATTTTAATTT TTTAAAAAAT TATAATTTAG TGGATGAAAA AGGTGAGATC 660TATTTCGCTA AAGATTTATC CACGCCTTCA AACCCGCGCA GTGTAGCGAT ACAAGAAATC 720AATCTTTTTT TAGAACCCTT AAAAAGCAGA GGGTGGAGCA GCGATGAAAA GCTTAAGGAG 780TTATATTATC AAAATAGACT TATTTTTAAG AATAATCGCC CTTATGAAAA ATATTACCTA 840AAAGAATCGC AAGATAATTG TTTGAGCGTG TTAGATTTTT ATAGCCGACA AGGCACAAAA 900GATTTAGAAA AATTAGGCTT AAAGGGGCTT TTTAAAACGC CAAAACCTGT AGCATTGATT 960AAATATTTAT TATTATGCTC CACCCCTAAA GATTCTATTA TTTTAGATTT TTTTGCAGGC 1020AGCGGGACAA CAGCGCAAGC GGTTATAGAA GTTAATAAGG ATTATTATTT GAATTGGTCT 1080TTTTATTTGT GCCAAAAAGA AGAAAAAATT AAAAATAACC CGCAAGCTGT TAGCATTTTA 1140AAAAACAAGG GGTATAAAAA CACGATTTCA GACATCATGC TGTTGCGTTT AGAAAAGATC 1200ATCAAAAGAA GTGAATACGA AATTTTAAAA ACAAAATCTA TTTTATTT 1248(2) SEQ ID NO 144: 144 Information

Sequence properties:

(A) length: 228 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...228

(xi) sequence representation: SEQ ID NO 144: AATTTTAGCG GTGAATCCAA AAAGCGCCTA AAGCACCCAG CCCCATTCCC AAGGGAATTA 60CCCAGGCGTT GCATCCAATT GTTTTCTTTT TTGGAAGACA CGATTTTTGA TCCCTTTAGC 120GGCTCTGGCA CGACTATTTT AGAGGCCAAC GCTTTAGGGC GTTTTAGCGT GGGTTTAGAG 180ATTGAAAAAG AATATTGCGA GTTGTTCAAA AAGCGTATTT TAGAGAGT 228(2) SEQ ID NO 145 information

Sequence properties:

(A) length: 651 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...651

(xi) sequence representation: SEQ ID NO 145: AGGAGATGTT GTAGGAGGGA AGACACGAAG AGATATGTGA TAGAAGTGGT TATATCTTTA 60AGCACAATGA CAAGTTTATT GTCAGCAGAG ACCCCTAAGC AAGAAAAGGC TATTAAGACT 120AGCCCTACCA AAAAAGGTGA AAGAAATGCT GCTTTTATAG GGATTGATTA CCAGTTGGGT 180ATGCTCAGCA CTACCGCTCA AAATTGTTCC CATGGGAATT GCAATGGTAA TCAAAGTGGG 240GCTTACGGCT CTAATACGCC TAACATGCCT ACAGCGTCAA ACCCAACAGG AGGCCTTACT 300CATGGCGCTC TAGGGACTCG TGGGTATAAA GGCTTAAGCA ACCAACAATA CGCTATCAAT 360GGTTTTGGGT TTGTTGTAGG GTATAAGCAT TTTTTTAAGA AAGCCCCACA ATTTGGAATG 420CGTTATTACG GATTCTTTGA TTTTGCAAGC TCTTATTATA AGTACTACAC TTATAATGAT 480TATGGCATGA GAGACGCTCG CAAGGGTTCT CAAAGTTTCA TGTTTGGCTA TGGGGCTGGC 540ACAGATGTGT TGTTTAACCC AGCTATTTTC AATCGTGAGA AACTTGCATT TGGGGTTTTT 600CTTGGGCGTT GCGATTGGTG GCACCTCTTG GGGTCCAACA AACTATTATT T651 (2) SEQ ID NO 146 information

Sequence properties:

(A) length: 321 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...321

(xi) sequence representation: SEQ ID NO 146: GGGGGCGTGT GCGGCGTATT ATCGTTACAA GCGCATTTGA GCTTTGAAAA TTGCTCTAAG 60CCCCTAGACT GCTCACTATT CGCTACAACT TGCACCCCGC AAAACCCGAT CGGCAGTTGC 120ATGGTCAGCT CTCAAGGGGG CGTGTGCGGC GTATTATCGT TACAAGCGCA TTTGAGCTTT 180GAAAATTGCT CTAAGCCCCT AGACTGCTCA CTATTCGCCA CAACTTGCAC CCCGCAAAAC 240CCGATCGGCA GTTACATGGTCAGCTCTCAA GGGGGCGTGC GCGGCGTATT ATCGTTACAA 300GCGCGTTTGA GTTTTAAAAA T321 (2) SEQ ID NO 147 information

Sequence properties:

(A) length: 1152 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1152

(xi) sequence representation: SEQ ID NO:147: AACTATAGTA ATAAAGATAA CCCCATGAGA TTTTTTTGCT TCTTTTTATT TTTTCTAACC 60TTTTCAAACG CGCAGATAAT GATGACTTTT GATTCCCAAA CTAACGCCAA ACTTTCGCGC 120TCCAACGAAC AGCTTTCTGA CATGCTTTAC AAACTCAATG AAAGTTTAAG AATCTATCAA 180AACGTGCTTT CTAACAACCA GGATCAACTT AAAGAAATCA AAAAGGCTAA CAGCACCCTA 240ACTAGCCAAA GGCGTTTTTT TAACGCTAGC CAGATCCGCC TTATGGACAC TGATGCACTA 300TTGAAACAAA GCGCTTTGGA ATTAGAAAAA TTACAAGCTT TAGAAAAACA CTTAAAAGAG 360AGCATGGAGC ATGAACGCTT AATCAAAGAA TCCCAAGCGC TTTTTTTGCA AGAGCATTGC 420CCTTATTTGA GCGGCGTTAA GAATTTAGAA GAGGCATCAA ACGCTTTAGA AGTCCAAGAA 480AAAAATAACG CCCTTTTCTT ACTCAAAGAG CCTAAACTCT TTCATTTGCT CTCACGATTG 540GATTTGATGA GCGCTTTAAA CGCCTTATGC GATCAGGTTT TAGAAAATGA AATACAGGAT 600CAACAATCCC ATAACAAAAC CCTAGAATAC AACGCCCTTA TGAACCATGA TTTTCAAGCC 660TATAAAGCCA TGCGTTTGAA AAAAATTAAA AACAAGCTTC AAAGCCAAAT CCAAGCTAAA 720GAAGACGCCC TAAAAACCTT TTTACCCCTA GAAAAACGCC CAGAGACTCT AGGCTCGAGC 780GATTGTTGCG ACAAAGAAAA TCTCAAATCA TGCGCTAACC AATTACAGCA ACGCTACCAA 840AACGCCCTAA TAGAGCGAGA TAAGGAATTA AAAAACGCTA AAAACAACAA AGAAAAGCAT 900GCTCTAATCT TAGCCAATTA CGAACACACT TTAAAAACCT TGAATATAGA ATTTTTAAGC 960GAATTGAGTG AGCAAATGGC GTTTTTGAAT GAGACCATGG CGTTAAACGC CCAAGTTTTA 1020GCCCTTTTAG CCCAACAACA GACTAAAAAG CCCTTCAATG TGAGCGATGG TTTGAGCGGT 1080GGGAAAGCCC TTATTAAAAA TATCCGCTTA GATCCGCATG GATTCCCTAG CTTTAAAAAT 1140TTTAAGCAAG AG 1152(2) SEQ ID NO:148 of information.

Sequence properties:

(A) length: 894 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...894

(xi) sequence representation: SEQ ID NO 148: TTAGTATTCA AAAAGCCCTT TTTTAAAAAT AGGTTACTAA ACGTTACTAA TAAGTTAAAA 60TTCGTGAAAA TAACCATAAT GATTAAAGAT TTTAACCACT ATTGTAGAAA AATAACGAGA 120GGGTTTGTAA AAATTCCCAC CAAAAAACAA GGAGCAAAAA AGATGAAAAA AGCGGGTTTT 180CTTTTTTTGG CGGCGATGGC TATCATTGTT GTGAGTTTAA ACGCCAAAGA TCCGAATGTG 240TTGCGTAAGA TTGTTTTTGA GAAATGTTTG CCTAATTATG AGAAAAATCA AAATCCTTCA 300CCATGCATAG AAGTCAAACC CGACGCCGGC TATGTGGTTT TAAAAGATAT TAACGGTCCG 360TTGCAATATT TGTTGATGCC AACGACTCAC ATTAGTGGCA TTGAAAACCC TTTGTTGCTT 420GATCCTTCTA CGCCTAACTT TTTTTACTTG TCATGGCAAG CGCGCGATTT TATGAGTAAA 480AAATACGGAA AACCCATTCC TGATTATGCG ATCTCTTTGA CGATCAATTC TAAAAAAGGG 540CGATCGCAAA ACCATTTTCA CATCCATATT TCTTGCATTA GCCTTGATGT GCGCAAACAG 600CTGGATAATA ATCTAAAAAA TATCAACAGC CGTTGGTCGC CATTATCAGG TGGCTTGAAC 660GGGCATAAAT ATTTGGCGCG TCGGGTAACA GAGAGCGAAT TAGCGCAAAA AAGCCCGTTT 720GTCATGCTTG CTAAAGAAGT GCCTAACGCG CACAAACGCA TGGGAGACTA TGGCTTGGCG 780GTGGTGCAAC AGAGCGATAA CTCCTTTGTC TTGTTAGCGA CACAATTTAA CCCATTGACT 840TTAAATCGCG CTTCAGCCGA AGAGATTCAA GATCATGAAT GCGCGATTTT GCGT 894(2) SEQ ID NO 149 information

Sequence properties:

(A) length: 537 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...537

(xi) sequence representation: SEQ ID NO 149: CTAAGGCGTC TAGCTTTGAA TACAATGAAT AGCGTGTTAG AATGTAAAGA ATTAGCGCTC 60TATGGAGGGA GTTTTGATCC TTTGCACAAG GCTCATTTAG CCATTATTGA GCAAACTTTA 120GAATTATTGC CATTCGTTCA GCTGATTGTC TTGCCCGCTT ATCAAAACCC TTTCAAAAAG 180CCATGTTTTT TGGACGCAAA AACCCGTTTT AAGGAATTAG AAAGAGCTTT AAAGGGAATG 240CCTAGGGTGC TGTTGAGCGA TTTTGAAATC AAGCAAGAAA GGGCTGTGCC TACGATAGAA 300AGCGTTCTTC ATTTCCAAAA ACTCTACCGC CCTAAAACGC TTTATTTAGT CATAGGAGCG 360GATTGTTTGA GGCATCTTTC TTCTTGGACT AACGCTAAAG AGCTTTTAAA AAGGGTGGAA 420TTAGTGGTTT TTGAAAGGAT TGGCTATGAA AAAATTCAAT TTAAGGGGCG TTATCACCCT 480TTAAAAGGCA TTGACGCGCC GATTTCTTCT AGCGCGATTA GGGCTAGTTT AGGGGTT 537(2) SEQ ID NO 150 information

Sequence properties:

(A) length: 807 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...807

(xi) sequence representation: SEQ ID NO 150: TCGTCAATAT TTGATTATAA TTATAAGGGA TTACATTTCT CCAATAAGAG ATATATCATG 60CTAGGAAGCG TTAAAAAAAC CCTTTTTGGG GTCTTGTGTT TGGGCGCGTT GTGTTTGAGA 120GGGTTAATGG CAGAGCCAGA CGCTAAAGAA CTTGTTAGTT TAGGTATAGA GAGCGTGAAG 180AAACAAGATT TCGCTCAAGC TAAAGCGCAT TTTGAAAAAG CGTGTGAGTT AAAAGAAGGT 240TTTGGGTGTG TTTTTTTAGG GGCGTTTTAT GAAGAAGGGA AAGGAGTGGG AAAAGACTTG 300AAAAAAGCCA TTCAATTTTA CACTAAAGGT TGTGAATTAA ATGATGGTTA TGGGTGTCGC 360CTACTAGGAA ATTTATACTA TAACGGACAA GGCGTTTCTA AAGACGCCAA AAAAGCCTCA 420CAATATTACT CTAAATCTTG TGAATTGAAC CATGCTGAAG GGTGTACGGT CTTAGGAAGC 480CTACACCATT ATGGCGTAGG CACGCCTAAG GATTTAAGAA AGGCTCTTGA TTTGTATGAA 540AAAGCTTGCG ATTTAAAAGA CAGCCCTGGG TGTATTAATG CAGGATACAT GTATGGTGTG 600GCAAAGAATT TTAAGGAGGC TATCGTTCGT TATTCTAAAG CATGCGAATT AAAAGATGGT 660 AGGGGGTGCT ATAATTTAGG GGTTATGCAA TACAACGCCC AAGGCACAGC AAAGGACGAA 720AAGCAAGCGG TAGAAAACTT TAAAAAAGGC TGCAAATCAA GCGTTAAAGA AGCATGCGAC 780GCTCTCAAGG AATTAAAAAT AGAGCTT 807(2) SEQ ID NO 151 information

Sequence properties:

(A) length: 258 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...258

(xi) sequence representation: SEQ ID NO 151: CATTTTAACA TCTTTACAGA AGATAATCGT GAAATCAGCG GGAGCACTGA CAAGCTCAGT 60TATAACGCGC TGAATGGGGA ATACAAATTA TTGCAAAATG CGGTGGTTAG AGAAGTGGGA 120AAATCTAATG TCATCACCGG CGATGAAATC ATTTTAAACA AAACCAAGGG TTATGCTGAT 180GTGTTGGGGA GCGCGAAGCG CCCGCTAAAT TTGTGTTTGA TATGGAAGAC ATTAATGAAG 240AAAATCGTAA GGCTAAAT 258(2) information SEQ ID NO 152

Sequence properties:

(A) length: 276 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...276

(xi) sequence representation: SEQ ID NO 152: CCCAAATCCC CTAAAAAGAT CGTAAAAAGA TACGAAAAAA GCGCTTGGAA AATGCCAAAA 60GAAAACACCA CCCACGAAGA CGCTTTAGCG AAATGCTTTG CGCCTGCAAT TTTTAAAGCC 120ATCATGCTGA ATAAATTGAT ATTGGCGGTT GTGGCTGCTC CCATTATAAA GATGCTTAAA 180TTGAGTAAAG AGATTTGGTG GAAAAAAATG GGCAAAAAAC ATGCGATAGA TTTTAAAATG 240AGGATAAAGA TATTGGCTTC TTTAGCCCCT AGCTTT 276(2) SEQ ID NO 153 information

Sequence properties:

(A) length: 555 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...555

(xi) sequence representation: 153: AATAAGGATC ATTTGATGTT AAACAAGTTT AAAAAAATCG TTGGCGTGGG TGTGTTAGTG 60GGCTGTTTAG GGGTTTTGCA AGCTAAAAAC AGCTTATTTG TCTTACCTTA TGAGCAAAGA 120GACGCTCTCA ATTCTTTAAT TTCTGGGATT AGCAGCGCTA GAGAGAACGT GAAAATCGCT 180ATTTATAGTT TCACGCACAG AGATATTGCA AGAGCGATTA AAAGCGTAGC GAGTAGGGGG 240ATTAAGGTGC AAATCATTTA TGATTATGAA AGCAATCACA ATAACAAGCA ATCCACTATT 300GGCTATTTAG ACAAATACCC TAACACGAAA GTGTGCTTAT TAAAGGGGCT TAAGGCTAAA 360AACGGGAATT ATTACGGCAT CATGCACCAA AAAGTAGCGA TCATTGATGA TAAAATCGTG 420TTTTTAGGCT CAGCGAATTG GAGCAAAAAC GCTTTTGAAA ACAATTATGA AGTGTTTTTA 480AAACGGGATG ACACAGAGAC GATCTTCAAA GCCAAGAGTT ATTATCAAAA GATGCTAGAA 540GGTTGCGTTG GGTTT 555(2) SEQ ID NO 154 information

Sequence properties:

(A) length: 645 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...258

(xi) sequence representation: SEQ ID NO 154: GGAAGAACAA TGAAATATTT ATGGCTTTTT TTAATATACG CTATAGGGCT TTTTGCAACA 60GATAAAACGC TAGATATTAT TAAAACCATT CAAAAACTTC CTAAGATTGA AGTGCGCTAC 120TCCATAGATA ACGATGCCAA TTACGCTTTA AAATTGCATG AAGTCTTAGC GAACGATTTA 180AAGACTAGCC AGCATTTTGA TGTTTCTCAA AACAAAGAGC AAGGTGCTAT CAATTACGCA 240GAACTCAAGG ATAAAAAAGT CCATCTTGTA GCGCTTGTGA GCGTGGCGGT AGAAAACGGC 300AATAAAATTT CACGATTAAA ACTTTATGAT GTGGATACAG GAACGCTCAA AAAGACTTTT 360GACTACCCCA TTGTAAGTTT AGATCTATAC CCTTTTGCAG CGCACAACAT GGCCATTGTG 420GTGAATGATT ATTTAAAAGC CCCTTCTATC GCTTGGATGA AGCGCCTGAT TGTTTTTTCT 480AAATACATTG GACCAGGAAT CACAAACATC GCACTAGCGG ATTATACGAT GCGTTACGAA 540AAAGAAATCA TCAAAAACAA CCGACTCAAT ATTTTCCCCA AATGGGCGAA CGCTGAGCAA 600ACGGAGTTTT ATTACACGCA GATGGCGGAA AAACGCCCAT GGTTT 645(2) SEQ ID NO 155 information

Sequence properties:

(A) length: 528 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix)feature:

(A) name/keyword: misc _ feature

(B) Position: 1...528

(xi) sequence representation: SEQ ID NO 155: GCAGCTATGA TGTTTAATAA TGATATAGAC AGCGCGACCG GATTTTACAA ACCGCTCATC 60AAGATTAACA GCGCTCAAGA TCTCATTAAA AATACAGAGC ATGTTTTATT GAAAGCGAAA 120ATCATTGGTT ATGGTAATGT TTCTACAGGT ACCAATGGCA TTAGTAATGT TAATCTAGAA 180GAGCAATTCA AAGAGCGCCT AGCCCTTTAT AACAATAATA ACCGCATGGA TACTTGTGTG 240GTGCGAAATA CTGATGACAT TAAAGCATGC GGTATGGCTA TCGGCAATCA AAGCATGGTG 300AACAACCCTG ACAATTACAA GTATCTTATC GGTAAGGCAT GGAGAAATAT AGGCATCAGT 360AAAACGGCTA ACGGCTCTAA AATTTCGGTG TATTATTTAG GCAATTCTAC GCCTACTGAG 420AATGGTGGCA ATACCACCAA CTTACCCACA AACACCACTA ATAATGCGCA TTCTGCTAAC 480TACGCTCTCG TGAAGAACGC TCCTTTCGCT CACAACACCA CTCCTAAT 528(2) SEQ ID NO 156 information

Sequence properties:

(A) length: 564 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...564

(xi) sequence representation: SEQ ID NO 156: ATTTTTAGAG CTTTTAGAAG AGGATTTTTT AGAAAAACAT TTGCATATCG CTTTACAGCA 60CACCATGATT TCATGCTAGA GAGAATGAAT CGAAGAAACC GCACTAAAAG CGATAGGGAA 120TTATTAGAGA TAATCGCTTC TAAGAATTTT GCTATCGGCA CGGATTTTAT TGTGGGGCAT 180CCGGGCGAGA GTGAAAGCGT TTTTGAAAAG GCGTTTAAAA ATTTAGAAAGCTTGCCTTTA 240ACGCATATCC ACCCTTTTAT TTACAGCAAG CGAAAAGACA CCCCCTCTAG TTTGATGCGT 390GATAGCGTGA GTTTGGAAGA TTCTAAAAAG CGTTTGAATG CGATTAAAGA TTTGATTTTT 360CATAAAAATA AGGCGTTCAG GCAATTGCAA CTCAAACTCA ACACGCCCCT AAAAGCCCTA 420GTGGAAGCGC AAAAAGACGG CGAATTTAAA GCCTTAGATC AATTTTTCAA CCCCATTAAA 480ATCAAAAGCG ATAAGCCTTT AAGGGCTAGT TTTTTAGAAA TCAAAGAGTA TGAAATTAAG 540GAGAGGGAAA ATCATGCCGT TTTC 564(2) information SEQ ID NO 157

Sequence properties:

(A) length: 237 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...237

(xi) sequence representation: SEQ ID NO 157: AAAGCACTGC CACAAGGTCG AAACAGAATG CGGTCGGATG TTGAAGTTTT ATCGCCTTTG 60CATAAAATAG ATGAAAAATA CCTTTTCCAT TTAAAGATTG CGGGGGAATT GGCGAGCATG 120GGTAAGATTT TAAGTGTATA TTTAGCCCAC AAGCACAGCG CGTATTTCAT TTTAAACGCT 180TTGAGTTACG GCTTTAGCCA CCAGGATAGG GCGATCATTT GCTTATTGGG CGCAATT 237(2) SEQ ID NO 158 information

Sequence properties:

(A) length: 705 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...705

(xi) sequence representation: 158: AAGGGAACAA AAATGAAAAA AGTCTATTTT AAAACTTTTG GGTGTAGGAC GAATCTTTTT 60GACACGCAAG TGATGGGCGA AAATTTAAAG GATTTTAGCG CGACTTTAGA AGAACAAGAA 120GCCGATATTA TTATTATCAA TTCTTGCACC GTAACCAATG GGACCGATAG CGCGGTAAGG 180AGTTACGCTA GAAAAATGGC ACGATTGGAT AAAGAAGTGC TATTTACTGG TTGCGGGGTG 240AAAACCCAAG GCAAAGAGCT TTTTGAAAAA GGGCTTTTAA AGGGCGTTTT TGGGCATGAC 300AATAAAGAAA AGATTAACGC GCTTTTACAA GAAAAAAAGC GTTTTTTCAT AGATGACAAT 360TTAGAAAACA AACATTTAGA CACCACGATG GTGAGCGAGT TTGTGGGAAA AACCAGGGCG 420TTTATCAAGA TCCAAGAGGG CTGTGATTTT GATTGCAATT ATTGCATTAT CCCAAGCGTG 480AGAGGGAGGG CTAGGAGTTT TGAAAAGAGG AAAATTTTAG AGCAGGTGGG CCTTTTATGC 540TCTCAAGGGG TTCAAGAAGT GGTTTTAACC GGCACTAACG TGGGGAGCTA TGGGAAAGAT 600AGAGGAAGCA ATATCGCGCG ATTGATTAAA AAATTAAGCC AGATTACTGG ATTGAAACGC 660ATTAGGATTG GGAGTTTAGA CCTAATCAAA TCAACGATGA ATTTT 705(2) SEQ ID NO 159 information

Sequence properties:

(A) length: 303 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...303

(xi) sequence representation: SEQ ID NO 159: GTTACGGCTT TAGCCACCAG GATAGGGCGA TCATTTGCTT ATTGGGCGCA ATTTAGCCAT 60AAAAAAATCC TTAAAGACTA CGTTATGGCC CACATGAGTG CGATGATGCC AAGCCTTTTG 120ACCTTGCAGT GGCTGAGTTT TATCCTTTCT TTAGCCGAAA ATTTGTGCCT GACAGACAGC 180CATCATTTAA AATACACGCT AGAAAAAAAC AAGCTTGTGA TCCATTCTAA TGATGCGCTT 240TACTTGGCTA AAGAAATGCT CCCCAAACTC ATTAAGCCCA TTCCTTGGAC GATAGAGTTT 300GCT 303(2) information SEQ ID NO 160

Sequence properties:

(A) length: 1227 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1227

(xi) sequence representation: SEQ ID NO:160: AGCGATGCGT TTTTAATCAT ACAAGATTTT AAAGAGCAGC GCATCATCCA TAAAATCATT 60CAAACCCATT TCAAACGCAT GCGTGTGGTT TTGAGCGTGA AAAGAGATAG CGAAAAAACT 120TTAGAAAACA ATGAAGAAAA TAAAGATGAA AAGCTCATTT TGATTGATGA ATTTGAAGTT 180TTAGCCAATA AATTCATTTC TCGTTTGCCT AATATCCCTA GCACCCCTAG AGAGTTTGGG 240TTAGGCAAGG GCGAGATCAT GGAGATTGAT GTGCCTTTTG GGAGCATTTT TGCTTATAGG 300CATATTGGCT CTATCAGGCA AAAAGAATAC AGGATTGTAG GGCTTTATCG CAACGATGTT 360TTGTTGCTCT CCACTAAATC TTTAGTCATC CAACCACGAG ACATTCTTTT AGTGGCAGGC 420AATCCGGAAA TTTTAAACGC GGTGTACCATCAAGTCAAAA GCAATGTGGG GCAGTTCCCA 480GCCCCCTTTG GTAAGAGCAT TTATTTATAC ATTGATATGC GATTGCAGAG CCGAAAAGCG 540ATGATGCGCG ATGTGTATCA AGCCTTGTTT TTGCACAAGC GTTTAAAGAG CTACAAGCTC 600TACATTCAGG TTTTACACCC CACTAGCCCT AAGTTTTATC ATAAATTTTT ATCGCTAGAA 660ACCGAAAGCA TTGAAGTGAA TTTTGATTTT TATGGGAAGA GTTTTATCCA AAAACTCCAT 720GAAGACCACC AAAAAAAAAT GGGTTTGATT GTGGTAGGCA GAGAGCTTTT TTTCTTGAAA 780AAACACCGAA GAGCCTTGCA CAAAACAGCC ACACCGGTTT ATAAAACCAA CACCTCTGGC 840CTGTCTAAAA CCACTCAAAG CATTGTGGTT TTGAATGAAA GTTTAAGCAT TAATGAAGAC 900ATGTCTTCAG TGATTTTTGA TGTGTCTATG CAAATGGATT TGGGCTTGTT GCTTTATGAT 960TTTGACCCTA ACAAGCACTA TAAAAACGAG ATTGTCAATC ATTACGAAAA TTTAGCCAAC 1020ACCTTTAACC GCAAGATTGA GATTTTTCAA ACCGATATTA AAAACCCTAT CATGTATCTC 1080AATTCTTTAA GAAATCCCAT TTTGCATTTC ATGCCTTTTG AAGAGTGCAT CACGCAAACG 1140CGCTATTTGT GGTTTTTATC CACTAAAGTG GAAAAATTAG CGTTTTTGAA CGATGATCAC 1200CCTCAAATTT TTATCCCTGT AGCGGAG 1227(2) SEQ ID NO:161 information.

Sequence properties:

(A) length: 192 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...192

(xi) sequence representation: SEQ ID NO 161: CCAAATGAAG CGAGCGCGGC TGTTAATGTG GGCTATAAGA TCAGTAAGAG TTTGACAGCG 60AGCGTGAAAT TAGAATATTT GGGCGTGATG ACGCATTCAG GCTTTACGGT AGGGAGTTAC 120AGACCCACGC CCGGCTCTAA AGCACTTTAT TCAGACAGGA GCCATCTAAT GACAACCCTT 180AGCGCCAAAG TC 192(2) SEQ ID NO 162 info

Sequence properties:

(A) length: 255 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...255

(xi) sequence representation: SEQ ID NO 162: TCCATAGTAT ACGGTAAAAA TAAATTATTC TCAGATGAAT TTTATGAAAA AATCGAGGAT 60ATTTTAACAA ATAACAACCC AAGATACAAA CAAGTGTGCA TTATTTTTGA TGCAGACATA 120AAAAAAGAGA ACCAAGAAAG CGATGCAGGT TTTGATAACA AGCTTAAGCA TATTCGTGAA 180AAATTCAAAG AAAAAGGGAC TGATTTTCCC AAAGAACAAA TCTTTTATTC CCTAACAATC 240AAGATGATGG CGATT 255(2) SEQ ID NO 163 information

Sequence properties:

(A) length: 438 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...438

(xi) sequence representation: SEQ ID NO 163: GTGCAAGCGT TTGATTATAA AATTGAAGTT TTGGCAGAGT CCTTTTCTAA AGTTGGCTTT 60AATAAAAAAA AGATTGACAT AGCTAGGGGG ATTTATCCTA CAGAGACTTT TGTAACCGCT 120GTGGGTCAGG GCAATATTTA TGCGGATTTT TTATCCAAAA GCCTTAAAGA TCAAGGGCAT 180GTTTTAGAGG GAAAAGTCGG CGGCACAATC GGTGGGATTG CTTATGACAG CACGAAATTC 240AATCAAGGCG GATCGGTTAT TTATAATTAT ATCGGTTATT GGGATGGCTA TTTAGGGGGT 300AAAAGGGCCT TGCTTGATGG CACGAGTATC CATGAGTGCG CGCTTGGCTC TGATGGCAAG 360GTGATTGATT CTATAGCGTG CGGGAACGCT AGAGCCAATA AAATCCGCCG TAATTACTTG 420ATGAATACCC CCTTCTCA 438(2) SEQ ID NO 164 information

Sequence properties:

(A) length: 741 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...741

(xi) sequence representation: 164: TTCCGCTATA AGGATATATT TGCGGCTAAA GGGGGGCGTT ATCAATCCAA TGCTCCTTAT 60ATGAGCTCTT ATACGCAAGG CTTTGAAATC AGCGCTAAAA TCAAGGATAA AAATGAGGGG 120AGCCATAAAT TATGGTGGTT TAGCTCATGG GGTAGGGCGT TCGCTTATGG GGAGTGGATT 180TATGATTTTT ACTCTCCAAG AACCGTGATT AAAAACGGGC GCACTCTAAA TTATGGTATC 240CATTTAGTGG ATTACACTTA CGAAAGGAAA GGGGTTAGCG TCAGCCCCTT TTTCCAGTTT 300TCGCCCGGGA CTTATTATAG CCCTGGGGTG GCTGTAGGCT ATGATAGTAA CCCTAATTTT 360AATGGCGTGG GCTTTAGATC CGAAACGAAG GCTTATATTT TGCTCCCTGT CCATGCCCCC 420CTTAAAAGGG ATACTTATCG TTACGCTGTG AAAGCTGGCA CCGCTGGGCA AAGCCTGCTC 480ATTAGGCAAC GATTTGATTA CAATGAATTT AACTTTGGGG GAGCGTTTTA TAAAGTATGG 540AAAAACGCAA ACGCTTACAT AGGCACGACA GGAAACCCTC TAGGCATTGA TTTTTGGACC 600AATAGCGTTT ATGATATAGG GCAAGCCTTA AGCCATGTGG TAACCGCTGA TGCCGTCTCT 660GGTTGGGTTT TTGGTGGAGG CGTGCATAAA AAATGGCTGT GGGGGACTTT GTGGCGTTGG 720ACTAGCGGCG CTTTAGCCAA A741 (2) SEQ ID NO 165 information

Sequence properties:

(A) length: 390 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(iv) original source:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...390

(xi) sequence representation: SEQ ID NO 165: TTTTCCCAAA GAACAAATCT TTTATTCCCT AACAATCAAG ATGATGGCGA TTTAGAAACC 60CTATTATTAG AAATTGCTAA ACACGATGAA TTTCTTAAAT GCTTTGAAGG ATACTTAGAA 120TGTATTAAAA GTAAAGAACA TTATAAACCG ATTAAAAACA TAAGAAAAAA TATGCTGTAT 180GCCTATTTAG AAGCGCTTGG ATTAGAGAAT TTGACCAAGA CCAATATAGA TGTTTTTGAT 240AGTAAAGGTA AAATAAAGAG TAGATATGAA GAAAACTACA AAAAATTAAC AGAAGAAGTT 300ATTGATTTCA GCTCGAATTC TCTCATTCCC CTTAAAAATT TTCTAGGGCA ATTCGCAGAA 360AATAAACAAA AAACAAATCC TAAAATTTTC 390(2) SEQ ID NO 166 information

Sequence properties:

(A) length: 213 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...213

(xi) sequence representation: 166: ATTTACTTTA GCGCCAAGCG ATTCAACACC AAAAACACGC ATGGCACGGG TTGTACTTTG 60TCTAGCTTGA TTGTGGGCTT ACTCGCTCAA GGGCTGGATT TAAAAAACGC TATCACAAAG 120GCTAAAGAGC TTTTAACTAT CATCATTCAA AACCCCTTAA ACATTGGGCA TGGGCATGGG 180CCTTTGAATT TGTGGAGCAT CAAAAAGCAT GTT 213(2) SEQ ID NO 167 information

Sequence properties:

(A) length: 699 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...699

(xi) sequence representation: 167: CGCCCTTCAT TCCAAAAACG CTGCGCCCAT TTTAACGCTA CTTTACCCAT TCTTTTAAAA 60GTGCTAGAAA AACAAGATAA AGACCTTTTT CTTTTGCAAG TGGGTAACAG GATTATCCCC 120ACCAAAAGCG AACAGGAATT AAAAATCAAT CAGCCTTATT TTGCGACTAT GCAAAGAAAT 180CAGCTGGGCG ACATTGTGCT TAAAAATTTA GTGCCTGCCC CAAAAATCTT AGACGCATTG 240GACGATTTGC CCGTTATTGA AATGAAGAAA TTAAAAGAAA TATTGAGCGC CAAAGACAAC 300ACCCCCCTAA AAGAATACAA AGAACTTTTG AGCGAAAAAT TAATCCATGC TAAAAGCTCG 360CAAGAGTTTT TGAATACAGC CAACATGCTT TTAAGCTTGC AATCGCAGGT TTTAAGCTTT 420GTGGTTGAAA ACGAACGCAA AAAAGCTTTT TTACAGATGA AAGCCAAAAA ACAAAGCGTT 480GATTTTTACG CTCTGTACCC TAACTTGGGC GAAATTGGCG GCGTTATTTA TTTAAAAGAA 540AAAGAGAAAC AGCTTTTTTT AAAAACCACC CTCCAAAGGA CCAAAGAGGT TTTAAAAGAG 600GCTCAAAACA CCCTTTTAGG CTTTTCTTTT GTGGAAATTG TGTGCGAAAA AACCCCCATG 660CTTTTTGCCT TTGAAGATCG CTTATTGGAC ACGCTAGGG 699(2) SEQ ID NO 168 information

Sequence properties:

(A) length: 462 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...462

(xi) sequence representation: SEQ ID NO 168: CTATTAGAGA TGATTTTTCG ATCAAGGCGT TCAAAATGGG GGGCGTTATG CAACGCTCAA 60ATCATTGAAT GCGTAGCGAA CGCTTTAGAA ACTTGTGATT TTGGGTTGTG CGTTTTAGAT 120CCGGTGATGG TGGCAAAGAA TGGGGCTTTG CTTTTAGAAG AGGAGGCGAT TTTAAGCTTA 180AAAAAACGCC TTTTACCTAA AACCAATTTA CTAACCCCTA ACCTCCCTGA AGTCTATGCG 240CTCACAGGCG TTCAAGCGCG AGACGATAAA AGCGCTTCAA AAGCGATGGG TGTTTTAAGG 300GATTTAGGCG TTAAAAACGC TGTGATTAAA GGGGGGCATA CAGAACATTT TCAAGGGGAA 360TTTAGCAACG ATTGGGTGTT TTTAGAAGAC GCTGAATTTA CTTTAGCGCC AAGCGATTCA 420ACACCAAAAA CACGCATGGC ACGGGTTGTA CTTTGTCTAG CT 462(2) SEQ ID NO 169 information

Sequence properties:

(A) length: 969 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...969

(xi) sequence representation: SEQ ID NO 169: TGGCTTCAAT CAAGGTGTTT TAGGGATAGC GCCTTTTGCC TTAGTTCCGA AAAATTGTTC 60GGTAAAAATT TGAATAAAGT GGTCATTTTG GCATTAAGAG ACATTATCCA TGAATATGGG 120CATACTTTAG GCTATACCCA TAACGGGAAC ATGACTTATC AAAGGGTGCG TTTATGCCAA 180GAAGGAAACG GGCCAGAGGC ACGCTGTGAG GGCGGGCATG AAGTGGAGAA AAACGGCAAA 240GAAGAGCTAG AATTCAGTAA TGGGCATGAA GTGCGAGACC ATGATGGTTA CACCTATGAT 300GTTTGCTCTC GTTTTGGCGG CAAAAATCAG CCCGCTTTCC CTAGCAATTA CCCCAATTCC 360ATCTATACCA ATTGCGCTCA AGTCCCCGCT GGGCTTATAG GGGTTACTAC CGCTGTTTGG 420CAACAGCTCA TCAATCAAAA CGCCCTGCCC ATTAATTTCG CTAACCTAAA TAGCCAAACC 480AGCCATTTAA ACGCCGGGTT GAATGCGCAA AATTTTGCAA CCTCTATGGT CAGCGCGATC 540GCGCAAAATT TTTCCACCAC TTCCACTACC ACTTACCGCT CTTCAAGTAA GAATTTTAGA 600AGCCCTATTT TAGGGGTTAA TGTTAAAATA GGCTACCAAC ATTATTTCAA TGACTACATC 660GGGTTAGCCT ATTACGGCAT TATCCAATAC AACTACGCTC AAGCTAACGA TGAAAAAATC 720CAGCAATTAA GCTATGGTGG GGGAATGGAT GTGCTGTTTG ATTTCATCAC CACTTACACC 780AATAAAAAGC AAGACCATCC AACTAAAAAG GTTTTTGCTT CCTCTTTTGG GGTGTTTGGG 840GGGTTAAGGG GCTTATACAA TAGCTACTAT GTCTTCAATC AAGTCAAAGG AAGCGGTAAT 900TTAGATATAG TAACCGGGTT TAATTACCGC TACAAGCATT CTAAATATTC CATAGCGTTA 960GCGTTCCTT 969(2) SEQ ID NO 170 information

Sequence properties:

(A) length: 426 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...426

(xi) sequence representation: 170: TATGATTTCC TAGGGGTTTC CTTGCATGCC CTTAGCCCCC TAGAAGAACA AGAATTTTTA 60ATTTCGTACC GCTTGAAAAT CGTTGATTCT AGAGTGATGG GTGAAGAGTA TTCTGTTTCT 120AAACCTATCG TTAGTCGCAT TAAAACAGCC CCCTATGTTT TAGACTATCA TTGCTCTATC 180ATCACTCGCA ACTTGCCCGA TTTGAAAAAC CCCTTGCTCC AAATAAAGCT AGAACGCTTC 240CTTTTAGAAA TAGCGTTAAA AAAAGAAAAA GAGCGAGTCA TTGACTGCCT TTTAAAAAGC 300CAAGTCGCTA TCACGCATTA TGATCACAGC TATAAAAACG GCACCACTAC CACAAGCATT 360CTTAACCTCA AAGCCTTAAG CGTTAAAGCG AGTTTAGATG GGAGATATGC TGTCTTTAGA 420TATTTT 426(2) SEQ ID NO 171 information

Sequence properties:

(A) length: 1032 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1032

(xi) sequence representation: 171 SEQ ID NO: GAGTGGTTAA TGCTAAAAAA GATTTTTTAT GGTTTTATCG TTTTATTTTT GATTATCGTA 60GGGTTGTTGG CCGTTCTTGT CGCTCAAGTT TGGGTAACTA CGGATAAGGA TATTGCTAAA 120ATTAAAGATT ATCGCCCCAG TGTCGCTTCA CAGATTTTAG ACAGAAAAGG GCGTTTGATC 180GCTAATATTT ATGATAAGGA ATTTCGTTTT TATGCGCGTT TTGAAGAAAT CCCCCCACGA 240TTTGTTGAAA GCCTTCTAGC GGTAGAAGAC ACCCTCTTTT TTGAGCATGG GGGGATCAAT 300TTAGACGCTG TCATGCGCGC TATGATTAAA AACGCTAAAA GTGGTCGTTA CACTGAAGGG 360GGTAGCACTC TAACCCAACA ACTCGTTAAA AACATGGTGC TCACACGGGA AAAAACCCTA 420ACCAGAAAAC TCAAAGAAGC TATCATCTCC ATACGCATTG AAAAAGTCTT AAGCAAAGAA 480GAAATTTTAG AGCGTTATTT GAACCAAACT TTTTTTGGGC ATGGGTATTA TGGCGTGAAA 540ACCGCAAGTT TAGGGTATTT TAAAAAACCC CTTGACAAAC TCACGCTTAA AGAAATCACC 600ATGTTAGTCG CCTTACCTAG GGCTCCAAGT TTTTATGACC CTACCAAAAA TTTAGAATTT 660TCACTCTCTA GGGCTAATGA TATTTTAAGG CGGTTGTATT CTTTAGGCTG GATTTCTTCT 720AACGAGCTCA AATCCGCTCT CAATGAAGTG CCAATCGTCT ATAACCAAAC TTCCACGCAA 780AATATCGCTC CCTATGTCGT GGATGAAGTG TTGAAGCAAT TGGATCAATT AGACGGGTTA 840AAAACTCAAG GCTATACCAT AAAACTCACG ATAGATTTGG ATTACCAACG CTTAGCGTTG 900GAGTCTTTGC GTTTTGGGCA TCAAAAAATC TTAGAAAAAA TCGCTAAAGA GAAGCCAAAA 960ACTAACGCTT CTAATGATAA AGATGAAGAC AACTTAAACG CCCAGCATGA TAGTTACAGA 1020AACGAGCACC GG 1032(2) SEQ ID NO:172 information

Sequence properties:

(A) length: 351 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii)type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...351

(xi) sequence representation: SEQ ID NO 172: ACGCCCAGCA TGATAGTTAC AGAAACGAGC ACCGGTAAGA TTTTAGCCTT AGTGGGGGGG 60ATTGATTATA AAAAAAGCGC TTTCAATCGC GCCACGCAAG CCAAACGGCA GTTTGGGAGC 120GCGATCAAGC CTTTTGTGTA TCAAATCGCT TTTGATAATG GCTATTCCAC CACTTCCAAA 180ATCCCTGATA CCGCGCGAAA TTTTGAAAAT GGCAATTATA GTAAAAACAG CGTGCAAAAC 240CACGCATGGC ACCCTAGCAA TTATACTCGC AAATTTTTAG GGCTTGTAAC CTTGCAAGAA 300GCCTTGAGCC ATTCGTTAAA TCTGGCTACG ATTAATTTAG CGATCGCTTG G351 (2) SEQ ID NO 173 information

Sequence properties:

(A) length: 624 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...624

(xi) sequence representation: SEQ ID NO 173: CCCAGAGACC ACACTTATAG CTTAGAAGAC AGCACGCCTC ATGGCTCTTT GTTAGGGAGG 60AATGGCGTTA CTTTAAATAT CCGCCAGGTT TTTTGGTGGG ATAATTTCAA CTGGTCCATT 120GGCTTTTATA ACACCTTTGG CAATTCAGAC GCTTTTTTAG GCTCTCACAC CATGCCAAGG 180GGGAATAACA CTTCCTATAT CAGTAATGAA ATCTCAGTAA CGACTAGGCA TGCCGGAATG 240ATCGGCTATG ATTTTTGGGA TAATACGGCT TATGATGGGC TGGCTGATGC GATCACTAAC 300GCGAACACTT TCACTTTTTA CACTTCGGTT GGAGGGATCC ATAAGCGTTT TGCATGGCAT 360GTTTTTGGGC GCGTCTCTCA TGCGAATAAA AATGCGTTAG GGCAAGTGGG GAGGGCTAAT 420GAATATTCCT TGCAATTCAA TGCGAGCTAT GCGTCCACTG AATCGGTTCT CCTTAACTTT 480AGGATCACTT ATTATGGGGC TAGGATCAAT AAAGGGTATC AAGCAGGGTA TTTTGGAGCG 540CCCAAATTCA ATAACCCGGA TGGCGATTTT AGCGCTAATT ACCAAGACAG AAGTTACATG 600ATGACCAACC TCACGCTGAA GTTT 624(2) information SEQ ID NO 174

Sequence properties:

(A) length: 396 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...396

(xi) sequence representation: SEQ ID NO 174: CCAAGAATAC ACGATATGGG CGATTTAGAT TCTCTAAACA TCAGCCCGGA TCCTAACACC 60CCTACCCTAT TGATTTTAAG CGCTTTAGAT AATTCTTTAA AAGATTACGC CCCCACCTTT 120AACGTCTTAA AAAAAACTTT TAAAGATCGT TTGAGGGTGC TTATTTTACT CAATCAACCC 180TATTCAAGCG ATGCAATCAA AGGCTTTATT GCGCCTTCTC AAACTGATTT GATGATTTTA 240AACCCTAAAG ATACCGCTCT TTTTGATCAT TTAAACCATG ACGCTTTAAA CCATTCTTTT 300AACATGCTCT TATATGACAA ACACCAATTG ATTAAAATGT ATCAAGGGAT CGTGCCAGCA 360GAAATGCTCC AATTTGATAT TTCCAATTTA AAGGAC 396(2) SEQ ID NO 175 information

Sequence properties:

(A) length: 366 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...366

(xi) sequence representation: SEQ ID NO 175: AGAAGAAGCC TTTATTATGT GTTTATAAAA TCGTATGCCA TTTTAGCGGA AGCGACAGCC 60CGTTTTGCGG GCGATTATGC GACAGAGAAT TTAACAAGCC GTATCGCTTT GCCTTGCTCA 120GATTATGTGG GTCGTGTGAT AGGCAAAGAC GGGAAAAACA TTGAAGCGTT TAAAAAGATT 180AGTGGGGTGG ATATAGAATT TAGCGAAGAC AGTAGCGAAT TGTGCTTGTC CAGTTTCAAT 240ATTTATCGGC GTGAAGTGGC GAGCGAGACG ATTAAAATTT TAATAGAAGA CGGCCGTATC 300CAGCCTAACA GGATTGAAGA GGTTTATCCT AAAATTCACC CGCAACATGG AAAAAGAATT 360GCTTTC 366(2) SEQ ID NO 176 information

Sequence properties:

(A) length: 750 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...750

(xi) sequence representation: 176: AAGACGGCCG TATCCAGCCT AACAGGATTG AAGAGGTTTA TCCTAAAATT CACCCGCAAC 60ATGGAAAAAG AATTGCTTTC TGAAGGAGAG AGCGTGGTGC TAGAATTAGA GCTTGGAACT 120ATGGAAGATG AGCTTAAAAT TTTAATAGGC AAAATGCGTT ATCGCTTTAG TTTTGGGCAA 180AACGCTTTAC AGCATTCTAA AGAGATCGCT CTTTTATCCG GCTTGATTGC AGAACAGCTT 240GGGGGGGATA AAAAACTCGC CAGAAGAGCC GGTATTTTGC ATGATATTGG TAAAGCGCTC 300ACTCAAGAGC TTGGGAGAGA CCATGTGAAT TTAGGGGTTG AGGTGTGCAA GCGCCATAAA 360GAAGACCCGG TTGTGATCAA TGCGATTTAT GCCCACCATG GGCATGAAGA AATCATGAGC 420GTGGAGTGCG CGAGCGTGTG CGCGGCTGAT GCGCTTTCTG CAGGGCGTCC GGGCGCTAGG 480AGAAAGAGCG ATGAAGAATA CGCTAAACGC ATGCAAGCTT TAGAAGAGAT CGCGTTAGAA 540TTTGATGGGG TGGAAAAGGC GTATGCGATG GAGAGCGGGC GAGAACTAAG AGTGATTGTC 600AAATCCAACC AAGTCAGGGA CAATCAAGTG CCTATTATTG CTAGAAAGAT CGCTAAAAGG 660ATAGAAGAGA GCACTCAGTA TGTGGGCGAA GTGGGCGTGC AAGTGGTGCG AGAAAATCGT 720TTCAAAACGA CCGCTACGCT AAGCAATGAT 750(2) SEQ ID NO 177 information

Sequence properties:

(A) length: 2412 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2412

(xi) sequence representation: 177: AGTTTGTGGC TTAAGTCAAA ATTCTTTCTT TTAATGGGCG TGGGTTTGCT CTCCCATTCA 60CTCAACGCTT TAAGCCTCAC GCTCACGCAA GGCAAAGAAG AAGGAGAAGA TTTTTCGGTT 120TTAACCTTAC GAAACGATAA GGCGTTTTCT TGCTCTTATG CTAATGAAAA ACCGCCGAGC 180GGGATTGAAG CGTCTTTATC TATTATACAC GCTAAACGCC CCATAGAATG CGTGATAGAT 240TCTATTCCTA AAGAGGGCTT TACCCCTTTA GAAAACGCTT TTTTCAATAT CACCTATTCC 300ATGCGCCAGC AACAATTCAT TTTACACATC AAACCCAAAG TGATGCGAAG GCTCACCCTT 360TTTTCTTTTG ATAGGGATTA TAAAAAAGCG ATCCCCCTTT TTGTGGAAAA CGACGCTAAA 420GCCAAGATGT GGCAAATCAT AGGCTATGAT CAAAAAATCC CTTTTTTGAG CGAAAAAGAC 480AACGCTCAAA AAGGCTTGAA TTTCCCCATT ATCATTAAAG ACGCTCAAAC CCCTATCATT 540CAAGAGCTGG ATGTGAATAA CAAACCCCTA CTCACCACAA AGGGCTATGA TTTAAACGCC 600TATTTAGAAG CTAAAAAACA AATGGATTCG CAAGCCTATT TTGACGCCTT ACGCACGATC 660AGCCGCGCGT TTAAAAATTA CCCTCAAACG ATTTTTAAAA AAGATCTGTA TTTATTAGAA 720ATTATCGCAT TAGGTAAATT AGGCATTAAA AAATCCTTAC TCATAGATAT TGGCACCCAA 780TGGATTAAAA ATTACCCGAC TGATCCTAAT ATCCCTGAAG CGCTATACTA TGTCGCCAAA 840GCTTTAGATG AAAACAACAA TTACAAACAA GCCGTGCGCT ATTACAAACG AATCCTTTTA 900GAATACAAAA ACTCCCGCTA CGCTCCCTTA GCCCAAATGC GTTTAGCCAT TGAAGCGGCT 960GAAGGCTCTG ATTTGAGCAA CGCTAATATG CTTTTTAAAG AAGCTTTTTC TAACGCCAAA 1020GACAAAGAGA GCGCGAGTGA AATCGCGCTT AATTGGGCTG AAGCAGAGAT AAACTATCAA 1080AACTTTAATA ACGCTAAATA TCTCATTGAT AAGGTGGTTC AATCCAACCC TGATTATCTT 1140TCTATGCACA GCGAATTAGC CCTAGAATTG CTCAAGTTAT TGAAAAAAAA CCAAATGAAT 1200GAAAGTGCGA TTGAGATCGC TCACTTGCTC CTCAATCAAG ATGATGACTT GAAAGCTAAA 1260GAGCAAGCGC TCTATGATTT AGGGGCGTTG TATGCAAGGA TCAAGGATTT TAAAAACGCC 1320CACCTTTACA ATCTGCAATA TTTGCAAGAC CATGCGGAAT TGGAGCGGGC TTCTGTCGTT 1380AGAGCACGCG ATGAAAAAGC CCTTTTTTCA ATGGAAGGGA ACACGCAAGA AAAAATCGCC 1440CACTACGATA AAATCATTCA AAATTTCCCT AATTCTAATG AAGCCCAAAA GGCTTTAGAG 1500TTGAAAGCCC AACTCTTGTT TGACAATAAG CACTATGCTG AAGTTTTAGG CATGCAAAAA 1560AATTTGCCCA AAGATTCTCC CTTGATCCAA AAAACGCTCA ATATCCTTGC TAAAACCCCA 1620TTAGAGGATC ATCGTTGCAA AGAAGCTTTA AAATACTTAT CCCAGATCAC CGCCTTTGCA 1680TTCAACCCCC AAGAAGAAAT CCAAGCCTTT GATTGCTTGT ATTTCGCATC GCTCAAGGAA 1740AAAGCGCAAA TTATTGCCCT AAACGCTTTA AAAGCGGCTA AAACCCCTAG CGAGAAATTA 1800ACATGGCTTT ATCGTTTGGG GCGCAATTAC TACCGCTTAG GGGATTTTAA AAATTCCACT 1860CTGGCTTCTA AAGACGCCTT AATCCTCGCT CAAAGCTTAA ATAAAAAAGA GTTTTATGAC ATTGCTTTTG TGTTATTTTC AGATTACATG CAAAACAATG AAAAAGGATT GGCCCTCAAT 1980TTGTATGCGT TTTTAGAAAA GCATTTCAAA GACGATAAAC GCATGGCGTT GGTTTATTTT 2040 63 AAATTATTAG AGAATGAAAA AGACCCTAAA AGCGTTAAAA TTTATGCCAC AAGCTTACTC AAACTCCAAG ACGCTTATAA GGATTATTCT TACACGCCCT TTGGCGAATT TGCCCTTATT 2160 GACGCTTACA GAACCACCAA AGATTATTCA AAAGCGTTAG AAACGCTAGA CAAACTCTTA 2220 AACCGCAGGC TTTCTTTAGA AGATCACCAA AAAGCCTTAT ACTTGCAATC CAGCTTATTG 2280 GATTTAACCA ATCAAAAAGC AAAATCTAAA GCCAGTTTAG AAAAATGCGT TCAATTAAAG 2340 362400 AACAAGGAGT CA 2412(2) SEQ ID NO:178 information.

Sequence properties:

(A) length: 1146 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1146

(xi) sequence representation: SEQ ID NO:178: AAACACCCAA ATCGTTTTTT CTTCAAAAGA ATTGAAAGAA CCGCACTCAA ACCCAATACC 60TTCTTAAACG CGCCCATGCA AAAACCACAA AATAAACCCA GCTCATCGCA ACAATCTCCT 120CAAAACTTTT CTTACCCAGA GTCCAAACTA GGCTCTAAAA ACTCTAAAAA CAGCCTTTTA 180CAGCCTTTAG TAACTCCTAG CAAAGTAAGC CCCACTAACG AAGTTAAAAC GCCAACAAAC 240GACGCTAATC CCCCTTTAAA GCATTCTTCA CAAGATCAAG AAAACAACCT CTTTGTAGCG 300CCACCCACTG AAAAAACGCT CCCTAACAAC ACCTCTAGTG CTGATGCGAG TGAAAACAAT 360GAAAGCAACG AAAATAGGGA TAATGTGGAA AAACAAGCGA TTAGAGATCC TAATATCAAA 420GAATTCGCAT GCGGGAAGTG GGTTTATGAT GATGAAAATT TACAAGCCTA TCGCCCAAGC 480ATTTTAAAAC GCGTTGATAA AGACAAAGAG ATTACAACAG ACATTACCCC TTGCGATTAC 540AGCACCGCTG AAAATAAAAG CGGTAAAATC ATTACCCCCT ATACTAAAAT CTCTGTTCAT 600AAAACAGAGC CTTTAGAAGA CCCTCAAACT TTTGAAGCTA AAAATAATTT CGCCATTCTC 660CAAGCCAGAA GCTCTACAGA AAAGTGTAAA AGGGCTAGAG CGAGAAAAGA CGGCACGACC 720AGGCAATGCT ATCTGATAGA AGAGCCTTTA AAACAAGCGT GGGAGAGCGA GTATGAAATC 780ACCACGCAAT TAGTGAAAGC CATATATGAA CGCCCCAAAC AAGACGATCA AGTAGAGCCG 840ACTTTTTATG AAACCAGCGA ATTGGCTTAT TCTTCCACAC GAAAAAGCGA AATAACGCGT 900AATGAATTGA ATTTGAATGA AAAATTCATG GAATTTGTGG AAGTGTATGA GGGTCATTAT 960TTAAACGATA TAATCAAAGA GAGCAGCGAA TACAAAGAAT GGGTTAAAAA CCATGTGCGC 1020TTTAAAGAAA GGGTGTGCAT GGCCTTAAAA ATAAAAAAGC AACCACGAGC CAAAAGCACG 1080CCTTTGAGTA TTGAAAACTC TCGTGTTGTG TGTGTCAAAA AGGGGAATTA TTTATTCAAT 1140GAAGTT 1146(2) SEQ ID NO:179 information.

Sequence properties:

(A) length: 315 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...315

(xi) sequence representation: SEQ ID NO 179: ACCAAAAAGT TAAACAATAC TCTATTCAAT AAAGGATTAA TTATTTTTAA AATGTTTAAA 60AAAATCATTT TTTTGTGCGT TTTTTTGATA GGGGGATTTG TCATTCCACC CCTTGAAGCC 120ATGCCTATTT TGCGCAATAA AACCCCCAAA AAAAATTACC AAGAAGCCCA TGAAAAGCTC 180TATAGAAGCA TCATTAACCG CCAAAAGCTC ACGCGTAAAA AAAGCGGGTG GTATTTTTTA 240GGGGGGGTTG GCGCTGTAGA AGCCATTAAG GACTATCAAG GCAAGGAAAT GAAAGATTGG 300ATGCCACGCT CAATT 315(2) SEQ ID NO 180 information

Sequence properties:

(A) length: 207 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...207

(xi) sequence representation: SEQ ID NO 180: AGTAAAACTT CCTATTGCAA TTCTTACAAG CGTAAGCTCC TCCCCTACCA CTTTCTACTT 60TTTCCATTAT GGGCGTGTTT TCACAATGTA AGCAGACCAT TTTCATTGAG CCATTTATTT 120CTCGTAAAAC GCCCTTACAG TCGCCTTTAT TTACATAATC AGAGCAACCA TAAAATGAGA 180CACCATTCAA TCCTCTTTGT ATCATTT 207(2) SEQ ID NO 181 information

Sequence properties:

(A) length: 1374 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1374

(xi) sequence representation: SEQ ID NO 181: CAAGATAAGG GGTTATTATT GAGTGTAGCA CTACCTAACT CAAACAACGC CTCTCAAAAC 60AACATTTTAA GCCTTTCTGT CCTTCACAAC CAGATTAAAA TGTCTTATGG TAATAAAGTG 120ATGGACTTTA CCCCTCCCAC CTTACAGGAT TACATTGTGG GCATTCAAGG ACAAAGCGCA 180CTCAATCAAA TTGAAGCTGT TGGGGGGAAT AACGCTATCA AGTGGCTTTC AACATTGATG 240ATGGAGACTA AAGAAAACCC GCTTTTTGCG CCGATTTATT TAGAAAACCA CTCTTTAAAT 300GAAATCTTAG GCGTAACAAA AGATCTTCAA AACACCGCAA GCTTGATTTC TAACCCTAAT 360TTTAGAAATA ACGCTACCAG CCTTTTAGAA ATGGCGAGTT ACACCCAACA AACCAGCCGT 420TTGACAAAAC TCTCTGATTT TAGGGCTAGA GAGGGAGAGT CCAATTTTTC AGAGCGCTTG 480TTAGAGCTTA AAAACAAGCG TTTTAGCGAT CCTAACCCTA GTGAGGTTTT TGTCAAATAC 540TCTCAACTCA GCAAACACCC CAATAACCTT TGGATTCAAG GGGTGGGAGG AGCGAGCTTT 600ATTTCTGGGG GCAATGGCAC GCTTTATGGC TTGAATGTGG GCTATGACCG ATTGGTTAAA 660AGCGTGATCC TTGGGGGTTA TGTGGCTTAT GGCTATAGCG GTTTTAACGG GAACATCATG 720CATTCTTTGG CTAATAATGT GGATGTGGGG ATGTATGCGA GGGCTTTTTT GAAAAGAAAC 780GAATTCACTT TGAGCGCGAA TGAAACTTAT GGAGGCAATG CGAGTCATAT CAATTCTTCT 840AATTCCTTGC TCTCTGTGTT GAACCAACGC TACAACTACA ACACCTGGAC AACGAGCGTG 900AATGGGAATT ACGGCTATGA TTTCATGTTC AAACAAAAAA GCGTGGTGCT AAAACCTCAA 960GTGGGCTTGA GCTATCATTT CATAGGCTTG AGCGGGATGA AAGGTAAAAT GCAAAATCCA 1020GCTTACCAAC AATTCGTCAT GCATTCAAAC CCTTCTAACG AATCGGTTTT AACGCTCAAC 1080ATGGGGTTAG AGAGCCGTAA ATATTTTGGT AAAAATTCCT ATTATTTTGT AACGGCGAGG 1140TTGGGTAGGG ATCTTTTGAT CAAAGCTAAA GGCGACAATG TGGTGCGTTT TGTGGGTGAA 1200AACACTTTAT TGTACCGCAA GGGGGAAATT TTTAACACTT TTGCGAGCGT GATCACAGGA 1260GGCGAAATGC ATTTGTGGCG TTTGATGTAT GTGAATGCGG GGGTGGGGCT TAAAATGGGC 1320TTGCAATACC AAGATCTTAA TATCACTGGG AATGTGGGCA TGCGAGTGGC GTTT 1374(2) SEQ ID NO 182 information

Sequence properties:

(A) length: 558 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...558

(xi) sequence representation: SEQ ID NO 182: CCCTTTGAAG CCTTGAATTT TTACTCCAAA AAAGCGTTGA ATGAGATTTT TGCAAACGCT 60AGGAAAATTT GCGGGAACAA GCCTTTGGGG GCGAATATTT TATACGCTAT CAATGACTAT 120GGCCGTGTTT TAAGGGACTC TTGTGAGGCG GGGGCGAATA TTATCATTAC AGGGGCTGGT 180TTGCCCACTA ACATGCCTGA ATTCGCTAAG GATTTTAGCG ATGTGGCGCT CATCCCTATC 240ATTTCCTCAG CGAAGGCTTT AAAAATCCTT TGTAAAAGAT GGAGCGATCG CTATAAAAGA 300ATCCCGGACG CATTCATTGT GGAAGGGCCT TTGAGTGGGG GGCATCAGGG CTTTAAATAC 360GAAGATTGTT TCAAAGAAGA ATTCCAATTA GAAAACTTAG TGCCTAAAGT CGTGGAAGCT 420TCTAAAGAAT GGGGGAATAT CCCTATCATC GCCGCGGGGG GAATTTGGGA TAGGAAAGAT 480ATAGACACCA TGTTAAGCCT TGGAGCGAGT GGGGTGCAAA TGGCGATCTC GTTTTTTAGG 540CACGAAAGAA TGCGACGC 558(2) information SEQ ID NO 183

Sequence properties:

(A) length: 264 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...264

(xi) sequence representation: SEQ ID NO 183: GCTATCCGGC TTAGGCTATC AATACGGGGG TTGATCAAAC GCATTGAAGA AGGTAACGCG 60CCTAAAATCG CATGCGTGAG CAATTGTGTA ACGCCTTGTA ACAGGGGTGA AGAAACTAAA 120AAGGTGGGCT ATTGTATCGC TGATGGTTTG GGGCGCAGTT ATTTAGGAAA CAGAGAAGAG 180GGGCTTTATT TTACCGGGGC TAATGGCTAT AGAGTGGATA AGATTATCAG CGTGCATGAA 240TTGATTAAAG AGCTTACAGA GGGT 264(2) information SEQ ID NO 184

Sequence properties:

(A) length: 852 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...852

(xi) sequence representation: SEQ ID NO 184: AATTTCAATC AAAGGGCTTT TTTGAAACGA GCGTTATGGT TAATTTTAGG GCTTTTTTAC 60GCGCTTAATG CAGAGAGCTT TAAAGATGTT TTGACTAAAG GGGATTACAC TTTTTTTAAT 120AAAAAGGTGG TTTCGCCTAT CAAACGCTAT GCGGATAGAT CGGCGTTTTA TCTGGGGCTT 180GGGTATCAAT TAGGGAGCAT TCAGCACAAC TCTAGCAACT TGAATTTATC CCAACGATTT 240AATAAGAGTC AGATTATTTT CAGCGATAGT CTAAGCCCTG TTTTTAAAAA TTCGTATGTG 300TCTAATGGTC TTGGCGTTCA AGTGGGCTAT AAGTGGGTGG GTAAGCATGA AGAGACGAAA 360TGGTTTGGCT TCAGGTGGGG GCTGTTTTAT GATTTGAGCG CTTCTCTTTA TGGCTCTCAA 420GAATCGCAGT CTATCATCAT TTCCACTTAC GGCACTTATA TGGATTTATT GCTTAACGCT 480TATAATGGGG ATAAGTTTTT TGCCGGGTTC AATCTGGGGA TCGCTTTTGC TGGAGTGTAT 540GACAGATTGA GCGATGCGTT ATTGTATCAA ACTCTTCTTC AAAACACTTT TGGCGGGAAA 600GTGAATTTAA ACGGCTTCCA GTTTTTGGTG GATTTAGGGG TTCGTTTAGG GAATGAACAC 660AACCAATTTG GCTTTGGGAT TAAAATCCCT ACTTATTATT TTAACCATTA TTATTCCATG 720AATAACATTA GCAATAATAG TGAAAATGTC TTAAAAGTTT TACGATTTTT AGAATACGGG 780ATCAACAGCT TGTTGTATCA AGTTGATTTC AGGCGCAATT ACTCGGTTTA TTTCAACTAC 840ACTTATAGTT TT 852(2) SEQ ID NO 185 information

Sequence properties:

(A) length: 198 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...198

(xi) sequence representation: SEQ ID NO 185: AAAATGCACA CGAGTTTTTT CCAAATCCCT TTGAATTTTG GGGTTCGTGT GAATGTGGAT 60AGGCACAATG GCTTTGAAAT GGGCTTAAAG ATCCCTTTAG CGGTCAATTC CTTTTATGAA 120ACGCATGGCA AGGGGTTAAA CGCTTCCCTC TTTTTCAAAC GCCTTGTCAT GTTTAACGTG 180AGTTATGTTT ATAGTTTT 198(2) SEQ ID NO 186 information

Sequence properties:

(A) length: 414 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...414

(xi) sequence representation: SEQ ID NO 186: ATCAAACGCA TCATTAAATC AAACGCATCA TTAAATCAAT TAAATACCAC TAGATACAAT 60ACCCCAAGTC ATCTTTTTTT CAAAAAAGGG GTAGGAATGG CAACCATTCA ACCATTCAAC 120CATTCAACCA TTCAACCATT CAACCATTCA ACCATTCAAC CATTCAATCA TTCAATCATT 180CAATCATTCA ATCATTCAAC CATTCAAGCA ACGCTACCTT ATTTTTATAA CTATTTATCT 240TTTTACAAAA ACCTATTTAA AAATCCCCTA TTTTTTATTA TTCCCCCTTT TATTAACCCT 300TTTATTAACC CTTTTATTAA CCCTTTTATT AACCCTTTTA TTAACCCTTT TATTAACCCT 360TTTATTAACC CTTTTATTAA CCCTTTTATT AACCCTTTTA TTAACCCTTT CATA 414(2) SEQ ID NO 187 information

Sequence properties:

(A) length: 579 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...579

(xi) sequence representation: SEQ ID NO 187: CGCTACCACC ACTTCTCCGG CCTATCAAGC TGTGGCTTTA GCGCTCAATG CGGCTGTGGG 60CATGTGGCAA GTCATAGCCT TTGGCATCAG CTGTGGCCCT GGCCCAATCT TGGCCCAGAA 120CATTTAGAAA ATGGGGGCGT TCGATCGTTT GACAACACGC CAAACTACAG CTACAACACC 180GGTAGCGGAA CGACCACCAC CACTTGTAAT GGAGCCAGTA ATGTAGGGCC CAATGGTATC 240CTATCTAGCA GCGAATACCA GGTTCTCAAT ACCGCTTATC AAACTATCCA AACCGCTTTA 300AACCAAAACC AAGGAGGCGG GATGCCTGCC TTGAATAGCT CCAAAAATAT GGTAGTCAAT 360ATCAATCAAA CTTTCACAAA AAACCCTACC ACAGAATACA CTTACCCCGA TGGGAATGGC 420AATTATTATT CAGGCGGTTC ATCAATCCCA ATCCAGCTAA AGATTAGTAG CGTCAATGAC 480GCTGAAAACC TTTTGCAACA AGCCGCTACT ATCATCAATG TCCTTACCAC CCAAAACCCG 540CATGTGAATG GTGGTGGTGG GGTCATGGGG GTTTGGCGG 579(2) SEQ ID NO 188 information

Sequence properties:

(A) length: 1254 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1254

(xi) sequence representation: SEQ ID NO 188: ATGGTGGTGG TGGGGTCATG GGGGTTTGGC GGTAAGACCG GGAATGTGAT GGATATTTTT 60GGCGATAGTT TTAACGCTAT TAACGAAATG ATCAAAAACG CTCAAGCCGT TTTAGAAAAA 120ACCCAACAGC TTAACGCTAA TGAAAACACC CAAATCACGC AACCAGACAA TTTCAACCCC 180TACACTTCTA AAGACACGCA GTTCGCTCAA GAAATGCTCA ATAGAGCTAA CGCTCAAGCA 240GAGATTTTGA GCTTAGCCCA ACAAGTAGCG GACAATTTCC ACAGCATTCA AGGGCCTATC 300CAACAAGATC TAGAAGAATG CACCGCAGGA TCAGCCGGTG TGATTAACGA CAACACTTAT 360GGTTCAGGTT GCGCGTTTGT GAAAGAGACT CTCAATTCCT TAGAGCAACA CACCGCTTAT 420TATGGCAACC AGGTCAATCA GGATAGGGCT TTGTCTCAAA CCATTTTGAA TTTTAAAGAA 480GCCCTTAGCA CTTTAGGGAA CGACTCAAAA GCGATCAATA GCGGTATCTC TAACTTGCCT 540AACGCTAAGT CCCTTCAAAA CATGACGCAT GCCACTCAAA ACCCTAATTC CCCAGAAGGT 600TTGCTCACTT ATTCTTTGGA TACCAGCAAA TACAACCAGC TCCAAACTGT TGCGCAAGAA 660TTAGGCAAAA ACCCCTTTAG GCGCATCGGC GTGATTAACT ATCAAAACAA TAACGGGGCG 720ATGAACGGCA TCGGCGTGCA AGCGGGCTAT AAGCAATTCT TTGGCAAAAA AAGGAATTGG 780GGGTTAAGGT ATTATGGTTT CTTTGATTAT AACCATGCTT ATATCAAATC TAATTTTTTT 840AACTCGGCTT CTGATGTGTG GACTTATGGG GTGGGTATGG ACGCGCTTTA TAACTTCATC 900AACGATAAAA ACACCAACTT TTTAGGCAAA AATAACAAGC TTTCTGTGGG GCTTTTTGGT 960GGCTTTGCGT TAGCCGGGAC TTCGTGGCTT AATTCCCAAC AAGTGAATTT GACCATGATG 1020AATGGCATTT ATAACGCTAA TGTCAGCGCT TCTAACTTCC AATTTTTGTT TGATTTAGGC 1080TTGAGAATGA ACCTCGCTAG GCCCAAGAAA AAAGACAGCG ATCATGCCGC TCAGCATGGC 1140ATGGAATTGG GCGTGAAAAT CCCCACCATT AACACGGATT ATTATTCTTT CATGGGGGCT 1200GAACTCAAAT ACAGAAGGCT CTATAGCGTG TATCTCAATT ATGTGTTTGC TTAC 1254(2) SEQ ID NO NO. 189 information

Sequence properties:

(A) length: 489 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...489

(xi) sequence representation: SEQ ID NO:189: GCTTTATCGC GCTGTCTTAG CGATCGTTTT AATCAGTATC CTGCCCTACA AAAAACCGAA 60CACCATTTCG TGGATTTTTT AAACCAGGAC AAGCATTACG CCATTATCCA AAGAGCGGAT 120AAAAGCATTT CCAGTAATGA AGCGTTGGCT CGTTCGCTCA TTGGGGCGTA TGTGTTAAAC 180CGAGAGAGCA TTAATCGCAT TGACGATAAA TCCCGCTATG AACTGGTGCG CTTGCAAAGC 240AGCTCTAAAG TGTGGCAACG CTTTGAAGAT TTGATTAAAG CCCAAAACAG CATCTATGTG 300CAAAGCCATT TAGAAAGAGA AGTCCATATC GTCAATATTG CGATCTATCA GCAAGACAAT 360AACCCCATTG CGAGCGTGTC CATTGCGGCT AAACTTTTGA ATGAAAACAA GCTCGTGTAT 420GAAAAGCGTT ATAAAATCGT ATTGAGCTAT TTGTTTGACA CCCCGGATTT TGATTACGCT 480TCCATGCCC 489(2) information SEQ ID NO:190

Sequence properties:

(A) length: 582 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...582

(xi) sequence representation: SEQ ID NO 190: TCCTTTAAAA AAAATGAAAG GTTATTGTTG CTTGTTTCTC GCTTTTTAAA CGCCATTGAT 60CCTTTTAATT TAGGGGTGTT GTTGAGCCGT TTCCAAATTA AAAATGGTTG TATTTATGGG 120GTGTGTTCTT ACAAGGTTTC AAAATTTACC CCTGGATATG AAGAAAGCAA AGCGCGAGTT 180TTAAACGCTC TCAATATTTT AAGCAAGCAT CAAATTTGGC AATCCAATCA AGAAAGCGTT 240ACAAAAGTCA AAGGAACTTT TGTTTTCATT TTAGAAAATG ACCTGCATTT AGACGAAAAC 300TCTTTTTATA AGAAACTTTT AAATCTGATT ATAGACAATG ACTTTTTTAA CCGCTCTCAT 360TTAGTAACTC CGAGCAATGG CACCAACTCC CACCCTGAAT TGCACCGCTC TATCACGCCC 420AGAGAAGCCG CTAGGATACA AAGTTTTAGC GATGATTATA TCTTTTATGG CAATAAAACG 480AGCGTTTGCA AGCAAATCGG TAACGCCGTG CCTCCTCTTC TAGCCCTAGC CTTAGGCAAA 540GCGATCTTAA AAAGCGCAAG AAATGATACA AATCCATCAC GC 582(2) SEQ ID NO 191 information

Sequence properties:

(A) length: 495 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...495

(xi) sequence representation: SEQ ID NO 191: ATGCAGGATA ATTTAGTGAG CGTGATTGAA AAACAAACCA ATAAAAAGGT GCGTATGTTA 60GAAATCAAAC CTTTAAAATC CAGCCAGGAT TTAAAAATGG TCGTTATTGA AGATCCGGAC 120ACTAAATACA ATATCCCGCT TGTAGTGAGT AAGGATGGTA ATTCAGTCAT AGGGCTTAGC 180AATATCTTTT TTAGCAATAA AAGCGATGAT GTGAAATTAG TTGCAGAAAC CAATCAAAAA 240ATCCAAGCCC TTAACGCTAC CCAGCAAAAC AGCGCGAAAT TGAACGCTAT TTTTAATGAA 300ATACCGGCTG ATTATGCGAT AGAGTTGCCC TCTACTAACG CTGAAAATAA GGATAAAATC 360CTTTACATTG TTTCTGATCC CATGTGCCCG CATTGCCAAA AAGAGCTCAC TAAACTCAGG 420GATCACTTAA AAGAAAACAC TGTGAGAATG GTTGTAGTGG GGTGGCTTGA AGCAATTCGG 480CTAAAAAAGC GGCTT 495(2) SEQ ID NO 192 information

Sequence properties:

(A) length: 345 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...345

(xi) sequence representation: SEQ ID NO 192: ACGGGAGCAA TCATGTTATC TTCTAATGAT TTGTTTATGG TCGTTTTAGG GGCGATTTTA 60TTGGTGTTGG TGTGCTTGGT GGGGTATTTG TATCTTAAAG AAAAAGAGTT TTACCATAAA 120ATGAGGCGTT TAGAAAAAAC TTTAGATGAA TCCTATCAAG AAAATTATCT CTATTCTAAG 180CGTTTGAGAG AATTAGAGGG GCGTTTGGAA GGCCTTTCTT TAGAAAAAAG CGCTAAAGAG 240GACAGCTCAT TAAAAACGAC TCTTTCGCAC CTTTATAACC AGTTGCAAGA AATCCAAAAA 300TCCATGGATA AAGAGCGCGA TTACTTAGAA GAAAAAATCA TTACT 345(2) SEQ ID NO 193 information

Sequence properties:

(A) length: 972 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...972

(xi) sequence representation: 193 SEQ ID NO: GAAAGGAAAA AAATGAACAC TAATTTAAAG AAAGCCTTGT TTTTAACTAC TCTTGGTTAT 60TTGCAAGCTA ATGAGGGCTT TTTAGCCATT ATGCCTGATG AAAATAAACA AGAAGACATT 120TCTCAAGAAC AGAAATTAGA ACACAAAATG GAGCAAAAAA TTGCTCCACA AAATACCCTT 180AAAAAGCAAC AATCAGCTCC TTTACAAAGT GCTGAGTTGT TACAAAGTCA AGTTAAAAGA 240GAAGTTAAAG AGCAAAAAAA GTCTCAAAAA CACCTAGTAG CTATGCAAAC TAAAAATGGC 300TTTTTCTTAG GCTCAGAAAT TGCTATTACA GGCACAAGTT TAAAACAAAG TTTAAGCCTT 360ATTTCTAATG CTACAGATGA TTTACTCACT TATAGCAAGA CTTCTAAAAA CGCTAATTTT 420AATATGGGAC TATTAATAGG TTATCAGCAT TATTTTGGAG CTAGTAAAAG GCATGGGATT 480AAAATCTCAA GCCATTTGTA TGGAGGCACA CCTAGTGATG TAAGCACAGA CATAAAAATT 540TACAAATCTA AAGTTAGCAC CAATTACACG CCTTTAAATT TTGGCATAGA TGTGAAGTAT 600TTGTTTGATT TTTTAAATGT CATTAAAAAG AACCGCCATA CACTAGGATT AAGTGTGGGC 660TTTGGCTGGC GTATGCAATA TTATTTTGCA AAAATAGACC CCATAAAAAC CAGCCATAGT 720GAGTTTATCA CTAATAAACC TAAAGATATT TTTAATCATG GTTTTTATCC CACTATTGGA 780CTACATTATT ACTTAAACCA TCATCAATTT GAAGTGAATT ATCGCTTTGG AGGAGCAATT 840AACTATCAGT CAGTTGTGCC TAGCAAAATT GTCGTTCAAA ACGGGAATTT TAAGGGCGAG 900GTCTTGTTTT CTAATTTTCT TACCAAAGCG ACTAATTCTA GCTACATAGC GTTCAACTAC 960GCTTATTTAT TT 972(2) information of 194 SEQ ID NO:194

Sequence properties:

(A) length: 411 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...411

(xi) sequence representation: SEQ ID NO 194: GCTAACGAAA AAATGGAGTT AATTAAGAAA TTGGAAAAAG AAAGCGAAGT TTTAAAGAAA 60GATTTACAAC AACATTCAAA CGAGCTTTTT AAAATGTTGA TTATTGATAA TGAAGATTTG 120TTTAAAGAGC AATTTGAGAT TATGTTTAAA GCATGGGTTG AAATCGTAAA AATGATGTTT 180GAATTAACCA AAAAAACCAA ATTTGATGGC GAAATGATTG GCTACACAGA AGAACTTTTA 240ACCTTTTTAG TTAGAGATTT TTTTAATGGG ATTTTTAAAT CCAAAGTAAT ACCTAAAATG 300CCTATTTTTT GCGGTGATGT TAAATGCGAA GATTTTAATG CCCTAAGAAG TTTAGTTTAT 360CTTTCTGTGC TTGAGTTGGA AGAAACGATA AATCCTAATA AAATCCCATT T411 (2) SEQ ID NO 195 information

Sequence properties:

(A) length: 681 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...681

(xi) sequence representation: SEQ ID NO 195: AATAAGGAAA ATAACATAAC CATTTGCGTT GCTAATGAAA AGGGTGGCAG TGGTAAAAGC 60ACGCTTTGTT TAAACTTAGC CGTGCAATTA CTCAAAGACA ATAAAGAAGT GGTTGTTTTA 120GATACAGATA GCCAAAAGTC TATGGAAACT TTTGCTACAA TTCGTGCTGA AAAAGAACGC 180CCCACTTTTA GCTTATTTAA TCGTAGTAGT GGCTTTAGCG ATACTTTAAA GCAAATGGTA 240TCTAAGTATG AAAATATCCT TATTGATACT AAGGGGGAAT ACAGCAAAGA AACCCAAAAA 300GCTATGCTTT TAAGTAATAT TGTGCTAGTG CCAACAACTC CTAGCCAATT AGACACTGAA 360GTCTTAGCTA ATATGCTAGA AAGAATTGAG CAACTCCAAG AGCTTAATGA AAATCTAAGA 420GCCTTAATTG TCATCAATAG AATGCCTACT ATTCCTACCC TTAAAGAAAG ACAAGCCTTA 480ATAGAGTTTA TTAAAGAAAA TAACCCTAGC GATAGGATTA CACTTTTAGA AAGCTCTTTG 540AGTGAGCGCA TTGTTTATAA GCGCAGTGTA AGCGAAGGCT TAGGGGTCAT AGAATACAGC 600GATAAAAAGG CTATCAATGA GTGGGTTAAT TTTTATAACG AATTAAAAAG CCATTTAGAA 660AAAGAGAAAA TACATGCGTT T681 (2) SEQ ID NO 196 information

Sequence properties:

(A) length: 315 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...315

(xi) sequence representation: SEQ ID NO 196: CGTTCAACTA CGCTTATTTA TTTTAATTTT AAGGAGCCAA TGATGTCAGA TGAAATCACG 60CAAGAAAACG AGTTAGAAAT TAACTCCAAT AATCAAAACC AAGAGCCAAA GGAAGTAGAA 120AAAATGCCAT TGAATAATAT TCAAAAAGCT AAGAAATTAA AAAACCACGC CAATTTAATT 180GTTCGACGCA CTGATGAGTT AGATAAGGTT ATCAATAAGC GTGAAAGCTT GCAAAGAGAG 240TTTAAAAGAC GCATTAAGCA CTTGGATAAC AAGATTGAAA CGCTTAGTAA CAATATTGAA 300GAATTAAAAA GAAAG 315(2) SEQ ID NO 197 information

Sequence properties:

(A) length: 519 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...519

(xi) sequence representation: SEQ ID NO 197: TCTATGAAAA AATATCAAAA CAAACGAAAG CTGGGTAAGC GTATCAATTG CTTTATTTCA 60AATGAATGTA AGGACATTTT AGAAAATTAT TTAAAAGTCA AAAAAATTAG CGTTACTGAG 120TGTATAGAAA GCCTTTTATT AGCCCTAGAC CCTAGCAAAG AAACACTAAG AGCAAGGGAT 180TTTTATGAAA GTTTGTTTAA AGTCATCAGT CTTAACCAAC ATGTCTATAA AGAACTCATG 240GCTAATGGTA ATAACATTAA CCAAATAGCC AAGAACACCA ACATTGCCAT TAAGTATAAC 300AAGCCCTTTT ATTTGCAGAA TTTAGCATTC TTAGAAGAGA TTTTTAAGGT TATGGATACA 360CTTAATAAAA ATGTAGAAGA ATGTAAAAAA ATCTCTTTGG AATTATTACT TCAAATTTAC 420AAAGAACAAA AAAGCCAAAC AGAATTTAAC GCCATTTCAA AAATTCTCAA CGCTCTTAAT 480GAAAAACAAT CTACTACTGA GCCAAAAAAG GACAACGCA 519(2) SEQ ID NO 198 information

Sequence properties:

(A) length: 327 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...327

(xi) sequence representation: SEQ ID NO 198: AAATCACCTT ATCGCCATAG TATATCTTCA CAGGTTTCTG TAGAAAACGA TGAGGAAATT 60ATTGAAGTTG AAAAGGGCGA AAATCAAGGG GCGTTTTCTT ACTTTTTAGG CGGCCCCACT 120TGTTTGGCGG GGGATTTTAT GGGGAGTTTT AGCTTTGAAA CGCCTTTAAA AAGGGGCGAT 180AAAATCGTGT TTCAAGACAT GCTCCATTAT ACGATCGTGA AAAACAACTC GTTTAATGGC 240GTGCCACTGC CAAGCCTGGC TAAAATAGAT TCGCAAGGTT TTAAGATCCT CAAAAGCTTT 300TCTTATGAAG ATTATAAAAA CAGGAAT 327(2) SEQ ID NO 199 information

Sequence properties:

(A) length: 399 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1..399

(xi) sequence representation: SEQ ID NO 199: GCTTTAGAGA AGAATGGGAC TGCTACTGCT AATAGCACTA GTAGCACTAG CGGTGCGACT 60GGTTCAGATG GTCAAACTTA CTCTCAACAA GCTATTCAAT ACCTTCAAGG CCAACAAAAT 120ATCTTAAATA ACGCAGCGAA CTTGCTCAAG CAAGATGAAT TGCTCCTAGA AGCTTTCAAC 180TCTGCCGTAG CTGCTAACAT TGGGAATAAG GAATTCAATT CAGCCGCTTT TACAGGTTTG 240GTGCAAGGCA TTATTGATCA ATCTCAATTG GTTTATAACG AGCTCACTAA AAACACCATT 300AGCGGGAGCG CGGTTAATAA CGCTGGGATA AACTCCAACC AAGCTAACGC GTGCAAGGGC 360GTGCTAGTTA GCTCCCTAAC GCTCTTTACA ACGTGCAAG 399(2) SEQ ID NO 200 information

Sequence properties:

(A) length: 252 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...252

(xi) sequence representation: SEQ ID NO 200: CTTATAAAAG AAGCGATGAT TCCAGTTTTT GGGAGTGAAA CAGGGATTTA TAACCATAAG 60GAGCAAAATT TTAAAGGCAA GGGCCGTTTC ATTCTCACTT CAAAGGACAG CAAGGTTGAA 120GGGCTTGACA TTTCTTATTC GCATGCATTA GCTATTATTG AAGCTCAAAG CATTCAAGCC 180AATTTGTTTT TAGATGAAAT CAAACAAAGC CAGAAAGAAA AGAAAAAATT CCCCACTTTC 240AAAGGAGGGT TT 252(2) SEQ ID NO 201 information

Sequence properties:

(A) length: 483 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...483

(xi) sequence representation: SEQ ID NO 201: CCCTTTCTAA AAAAGAATAA ATTTTTACAA ATTTGTCAAT ATTTTAGCGC GCATTTCAAG 60CAAGTGTTAA AAAATGAAAA GCCCTTAGTT TATTATGGGG TTTTAAAGGC TAAAGCCCCT 120AATTGGGCTT TATGGGTTTA TGAAAAACCC TTAAAAAAAG AAATTTACAT GAACGATAAG 180GAAGTGGTGG TTTATGAGCC TAATTTATTC CAAGCGACTA TCACGCCCTT AAAAGACAAG 240ACGGATTTTT TCACCATTCT CAAGCAATTG AAAAAGCAGA CTGACGGCTC TTTTAAAACG 300ACTATCAACA AGACCACTTA TCGTTTGGTT TTTAAAGACG GCAAGCCTTT TTCGTTGGAA 360TTTAAAGATG ACATGAATAATCTTGTTACG ATCACTTTTT CTCAAGCAGA AATCAACCCT 420AAAATTCCTA ATGAAATCTT TGTTTTTAAC CCTAAAGATG AAAATATTGA TATTGTACGC 480CAG 483(2) information SEQ ID NO 202

Sequence properties:

(A) length: 213 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...213

(xi) sequence representation: SEQ ID NO 202: CCTAGCTTTT TGAAAGAAAA ATTTGATTTT TTTAAAGGCA AAAATTTTAA AATTGTCTAT 60TGTATTGGCG AAGATTTAAC GACCAGAGAA AAGGGTTTTA GGGCTGTAAA GGAATTTTTA 120AGCGAGCAAT TAGAAAATAT TGATCTTAAT TATTCCAATT TAATTGTGGC TTATGAGCCT 180ATTTGGGCGA TTGGCACTAA AAAAGCGCGC TTT 213(2) SEQ ID NO 203 information

Sequence properties:

(A) length: 465 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...465

(xi) sequence representation: SEQ ID NO 203: CGCGATGTTA GATTCCATGT TAGGGACCTA GTTCGGCAAC TCAAGGGCAA GCATTTGATT 60GAAGTTTCAG ATGTGATTAA CGACACCACT CAGCCCAATT TGGACATGAA TCTTTTGACG 120ACCGAAATCG CGCGGCAGTT GCGATTGCGA TCTAATGGGA GGTTCAATAT CACAAGGGCG 180AGTGGAGGGA GTGGTATTGA AGCAGACAGC AGAATGGTGA AACAGCGCGA AAAAGAACGA 240GAGAGCGAAG AGTATAATCA AGACACCACT GTAGAAAAAG GCACTTTAAA AGCCGCTGAT 300TTATCTTTAA GTGGTAAAGT ATCCAGTATC GCAGCCTCTA TTAGTAGTTC TAGGCAACGC 360TTAGACTACG ACTTCACCCT AAGCCTTACC AATAGGAAAA CGGGTGAAGA GGTATGGAGC 420GATGTTAAGC CTATTGTGAA AAATGCTAGC AATAAGCGTA TGTTT 465(2) SEQ ID NO 204 information

Sequence properties:

(A) length: 657 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...657

(xi) sequence representation: 204: ATTAAATCTG TTTTAGGTTT AATTTTGATC CAACAAAATT TTAAAACACT TAAGGAGTTG 60TATATGTTAG TTACAAAACT TGCCCCCGAT TTTAAAGCGC CTGCCGTTTT AGGAAACAAT 120GAGGTTGATG AACACTTTGA GCTTTCTAAA AATTTAGGCA AAAATGGTGT GATCCTTTTC 180TTTTGGCCAA AAGATTTTAC TTTTGTATGC CCTACAGAAA TCATTGCGTT TGACAAAAGA 240GTGAAAGACT TCCACGAAAA AGGCTTTAAT GTGATTGGCG TGTCTATTGA CAGCGAACAA 300GTGCATTTCG CATGGAAAAA CACCCCTGTG GAAAAAGGCG GTATCGGTCA AGTGTCTTTC 360CCTATGGTGG CTGATATCAC TAAGAGCATT TCTAGAGACT ATGATGTGCT GTTTGAAGAA 420GCGATCGCTT TGAGAGGTGC TTTTTTGATT GATAAAAACA TGAAAGTAAG ACACGCAGTG 480ATCAATGACT TGCCATTAGG TAGGAATGCA GATGAAATGC TTCGCATGGT AGACGCTCTC 540TTACACTTTG AAGAACATGG TGAAGTATGC CCAGCAGGTT GGAGAAAAGG CGATAAAGGC 600ATGAAAGCAA CTCACCAAGG CGTTGCAGAG TATCTTAAAG AAAATTCCAT TAAGCTT 657(2) SEQ ID NO 205 information

Sequence properties:

(A) length: 339 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...339

(xi) sequence representation: SEQ ID NO 205: GGAGTAATAA TGGAACACCA TAAAGCGCAC ACAACCATTC AGGCTTTACA AGCCAAACGC 60AAAAGGTTGC TAACCGAATT AGCCGAGTTA GAAGCAGAAA TAAAGGTGAG CAGCGAACGA 120AGGAGCAGTT TTAACGTTTC GCTCTCGCCG AGTTTGTTAG CCGAAATAGA AGAGATAGAA 180TACGAAGAAA AAATGAGCAA AGAGCGAAGA ATCCATCACA ATCTTTTGCT TTCGCCCAGT 240TTCATGGCTA AAGTGGATGA ATACATGAAA GAGAAAGGTT TTCCTAATCG ATCGCTTCTC 300TTTGAAAAAG CGTTGGAGTT TTATATGCTA AAACACCCA 339(2) SEQ ID NO 206 information

Sequence properties:

(A) length: 561 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...561

(xi) sequence representation: SEQ ID NO 206: GGTTTTGTTT GCGGTAGCGT TTTATTTCAA TTAGGAGTTT TTATGGGGTT AAAGAATAAA 60ATCAAGGGTT TTGTTAAAGA GAGAATGCCT TTTGTAATGA GATGCGTTCG TGGTTTAAAA 120GGGGCCAAAG ACACCCATGA AAACGCCCAT GATAGGGACG CTTATTGTGG AATCAATCGT 180GAAATTAAGG AAATGCTAGA GGCTAAAAAA CTTCATTTTC TTCAAGAAAA AGCTTTATTC 240AACCACGACC ATCAAGAAAG CGTGTTTTTA GCTATCGCCT CTTTAAATAA TGAAAGTTTC 300ATTGAATACA ACAAGAGTAT TTATAAAAAT AGTTCTCTTA ATTATAATTA TGGGGGGCAT 360TTAGAAGATA GGGTCATCCA TCCCACTTTA ACTTTACCCA ATCCCACGCA TTCGGGTTAT 420TTTGACTATG ATAAAAAAAG TCAAAACCCT AAAAGCCCTC TAAACCCATG GGCTTTTATT 480AGAGTCAAAA ACGAAATCGT TACTTTAGAA GAGAGTTTGT TTTCTATGCT TCCTGCCGTT 540CAAAGGGGGG GTCATTGGTT T561 (2) information SEQ ID N0:207

Sequence properties:

(A) length: 690 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...690

(xi) sequence representation: 207: AAGAGAGTTT GTTTTCTATG CTTCCTGCCG TTCAAAGGGG GGGTCATTGG TTTTAATGAT 60TGCGATGATG GCTCTAAAGA AGTGGTTTTA GAGTTTTGCA AAAAGTTCCC CTCATTTATC 120CCTATCAGCT ATCCTTATGA AGTCATACTA AAGGATTGTC CGAGTTTGTG GCACCAACTC 180TATCATTACT GTAATTATAC GCTTTCTTTT ATCCCTAAAA ATGAGTGGGT AGTAAAAATT 240GATTGCGATC ATATCTATGA CGCTAAAAAG CTTTATAAAA GTTTTTATAT TCCTAAGAAT 300ATTAAAGAGG TTGTGATGTA TTCGCGCATT AATTTTGTGG TGCGAGATTT TGAAGTGTTT 360GTTCGTAACG ATGGGGATTT TGGGTTTTTA GACGCATGGG GGGATCATTG GTTATTGTAT 420AACGATTGCG AGCCTTTTGA AATTTGGCGC TACAATGATG AAAGTTATGA AGTCCTAAAG 480CTTAAAGATA AACACCATAT TAAAGATAAG GAAATGGTGC AATGGCACTT CCCTTTGGCT 540AAAAAGAGGC GAAACGCTAT TGTTTATGAC GATTTGATCC CTTTAGAAGA ATTCAAAAAA 600CGCCATGCCG ATTTGATAGG CACAAGGATT GAAGAAAGCA TGCTAGATGA AAAGAGGATT 660TTAGAGGTAT ATCAAAAATT CCGCTTGCCT 690(2) SEQ ID NO:208 information

Sequence properties:

(A) length: 258 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...258

(xi) sequence representation: SEQ ID NO 208: CTAAGTTTAA ATAAAAAAAT GATGTTTGAA TTAACCAAAA AAACCAAATT TGATGGCGAA 60ATGATTGGCT ACACAGAAGA ACTTTTAACC TTTTTAGTTA GAGATTTTTT TAATGGGATT 120TTTAAATCCA AAGTAATACC TAAAATGCCT ATTTTTTGCG GTGATGTTAA ATGCGAAGAT 180TTTAATGCCC TAAGAAGTTT AGTTTATCTT TCTGTGCTTG AGTTGGAAGA AACGATAAAT 240CCTAATAAAA TCCCATTT 258(2) information SEQ ID NO 209

Sequence properties:

(A) length: 492 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...492

(xi) sequence representation: SEQ ID NO 209: TTTTCAAGAA AGACAGACAA AAACGCTCAA AAAGACGAGC AAAAAAATGA ACAAGAAGAA 60CAAAGGCGTT TAAGAGAGCA ACAACGCTTG AAACAAAACC AAGAAAACCA AGAGATGTTG 120AAAGGTTTGC AACAAAATTT GAATCAATTC ACGCAAAAAT TAGAAAGCGT TAAAAACAAG 180ACTTTAGATT TGCAAATCCC TAAACAAGAT GGGGTTGATG AAAAGGCTTA TCAAGAGTGG 240TACGCTCAAA TCTATCAAAT TTTATATAAA GGCTGGAGGG GCGTTTTTTA TCACAAGGCT 300TCAGTGAGCG TGCTGATTAT GATCACTAAA GATGGAGAGT TTGATTATAC CATTCTTAGC 360TACTCTGATT TTAAGGATTA TAACAAGAGC GTGATGACCC TTTTAGATGA TTTAAAGAAA 420GTGGATTTCC CCCCATATCC TGGAGGAAAC ATGATTTCTA TTAAAGTTAA TTTTACGACT 480AAGGAAGAAC AA 492(2) SEQ ID NO 210 information

Sequence properties:

(A) length: 204 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration:ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...204

(xi) sequence representation: SEQ ID NO 210: AGAGCGCGAT TACTTAGAAG AAAAAATCAT TACTTAGAAA ACAAATTTAA AGACATGGGG 60CATTATGCCG CTAGCGATGA AGTCAACGAA AAACAGGTTT TGAAAATGTA TCAAGAAGGC 120TATAGCGTGG ATTCTATTTC TAAAGAATTT AAAGTGAGTA AGGGCGAGGT GGAATTTATA 180TTGAACATGG CAGGGTTAAA ATGG 204(2) SEQ ID NO 211 information

Sequence properties:

(A) length: 291 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...291

(xi) sequence representation: SEQ ID NO 211: ACGAAATTGG ATACAATCAG CTTAAAAAGG ATACAAATGG AAAAATTACC TAAAAAACGA 60GTTTCTAAAA CCAAATCACA AAAACTTATC CATAGCCTAA CCACCCAAAA AAACAGAGCC 120TTTCTCAAAA AAATCAGCGC TAATGAAATG CTTTTAGAGT TAGAAAAAGG GGCGTTTAAA 180AAAAATGAAG CCTATTTTAT TTCTGATGAA GAAGATAAAA ATTACGTTTT AGTGCCGGAC 240AATGTGATCT CTCTTTTGGC AGAAAACGCC AGAAAGGCTT TTGAAGCCAG G291 (2) SEQ ID NO 212 information

Sequence properties:

(A) length: 816 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...816

(xi) sequence representation: SEQ ID NO 212: AGGAGTATTA AAATGAAACA AAGTTTGCGC GAACAAAAAT TATTGAAAAT TTTGGAAAAT 60GATGTCTTGA CGATTTTGGA TAGTTTTTCT AATTACCTTT TTGAACTGAG AGAAGAATTG 120GACTTCATAG AAGAAGAAAT GGAAGGTGAA ATCACTGAAC AAAACCTTAC CGCTCTTTAT 180GATTTTTCTA ATTTCTTAGA AGACCATGTC AATGTGTTTT ATGAGAATGT TTTGAATATA 240GATGATGTCA AAACAGAACA CCTTTATTCA GGTCTCATAG ATAGTCTTAA CGCTAATCTT 300CACTTTGTCA AGTCATTTCT CAGTAATCAG GATTTAGACT TCCGCTTTTT TAAAGAAATA 360AACGATGGGC AAGATCCCCA AAAAACATTA TCAAGATTGA TTCCTCTTCA AAGTGGGAAG 420AATGATGCAA GCTCGTTTAA AGCCAATAAT TCTTTTGTTT CATTAGTTTA TGTTTATGCT 480TACTTCATGC TAGAAACTAT CAGGCAGTCG TATAGGATTC TCAGATTACT AGAAAAACCT 540ATCAATAACA ACATAAGCGA GGACATGCAG AGCGATATAG AGAATTTTTT TGTTCAAGCA 600AATTTTTTAG AATACTATGT TCAGAACAAA ATATACCCAA CCAATCATGC CTATGACTTC 660ACGCATTTGA TCATGGACTC CATTATTCCT AATTGGATTC AGATTGATAT GAGCGTTGAA 720GCTAAAAAGA AAGAGCTTTT TGAAAAATAT TTTCAAAACA TTGATGAAGT AACAAACAAA 780ATGCTCGCTC AAGAAAATCA AAACAAAAAC AGCGAT 816(2) SEQ ID NO 213 info

Sequence properties:

(A) length: 687 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...687

(xi) sequence representation: 213 SEQ ID NO: GTGAAAGGCG AGAAAAACGC TTGGTATCTG GGGATTAGCT ATCAAGTCGG TCAGGCTTCA 60CAAAGTGTTA AAAACCCCCC CAAAAGTAGT GAATTTAACT ATCCTAAGTT CCCTGTGGGT 120AAAACCGACT ATCTGGCCGT TATGCAAGGC TTAGGGCTTA CTGTGGGTTA TAAGCAGTTT 180TTCGGGGAGA AAAGATGGTT TGGTGCGCGC TATTACGGCT TTATGGATTA TGGGCATGCC 240GTGTTTGGAG CGAACGCTTT GACATCAGAT AATGGTGGGG TGTGCAAACT CAATGAGCCA 300TGCGCGACCA AAGTAGGGAC TATGGGCAAT CTGTCTGACA TGTTCACTTA TGGTGTGGGT 360ATTGACACTT TATACAATGT CATTAATAAG GAAGACGCGA GTTTTGGTTT CTTTTTTGGG 420GCTCAAATCG CGGGTAACTC TTGGGGTAAT ACGACAGGGG CCTTTTTGGA AACTAAAAGC 480CCTTATAAGC ACACCTCCTA TAGCCTTGAT CCGGCGATTT TCCAGTTCCT TTTTAATTTA 540GGGATTCGCA CCCATATTGG TCAGCATCAA GAATTTGACT TTGGCGTGAA GATTCCTACT 600ATCAATGTTT ATTATTTTAA CCATGGGAAC TTGAGCTTCA CTTACCGCCG TCAATACAGC 660CTTTATGTAG GGTATCGTTA CAATTTC 687(2) SEQ ID NO:214 information

Sequence properties:

(A) length: 195 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...195

(xi) sequence representation: SEQ ID NO 214: AGCGCTGTAG TGGAGAGCGT GGTTATTTTA AAGATTGACA TCAATCAGGG GCGTTCTTGC 60TCGCTCTACC CCACGCCTAA AAGCGTTTCT TTAGTGAGGA ATCAAAGCGT AGCCTATGAA 120ATTTTATGCG AAAACCAGCC GCTATGGATA GAAGTTAGCA CCAATTTAGG GCAAACGCTA 180CCTTTCAGTT TAATT 195(2) SEQ ID NO 215 information

Sequence properties:

(A) length: 1095 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1095

(xi) sequence representation: SEQ ID NO:215: CGCTTTAAAC ACTTTAGGGG TGGGGGTTTT CCCCACCACA ACCTCAACGC ATGTGGTGCT 60AAACCCACCG GACAAGTCGT ATTCTATCCA ACTAATTCCC TTTTAGGCTC TACTTCTTCA 120AACAGCAATA ACCAACAACA ATACAACAAC ACCCTTTTAA TGAACACCTT ACAAGGGGAA 180TTAAGCACTA ACAATCAAAA TAACCCCAAT GGTTGCGCCA ATCAAATCCA GTGTTTAGAG 240CAATTCATCC AAAATTTAAC CCCTTTAGCC GCAACCCCCA CTTCAACTAA CCAGGCCAAC 300CAGCAAGTCC AAGCCATCGC TCAAAAACTT CAAAGCGTTG CTATCAACGC TTTAGACAAC 360AATGCGATCA ACAACACCAC CTATAATTTA AACAACTTGC ACAACGCTTT GAATTTCCAA 420GCCTATCAAA GCACGATAGA ACAATACAAT AACGCTTTAA AGCAAATTTC GTGGATTAGT 480TTTAGCGAGC CTAAAAACTT GCTCAAAAAC ACTTCCAATA ACTACCAAAT CGGCACGGTT 540ACCAACGATC AAGGGCAAAA TATCAGCGCC TATGATTGCA CAAGCGCTAC CGGAAGCCTT 600TCTAGCGATG CTTCTAGTGG GATTTCATGC TCAGCCACAA GCTCCACAAG CAACACAAAT 660AGTTTTGACA ATTCTTTAGT CGCTACCTCC AAAGTCCAAA CCATCAACGG CAAAGAGCAG 720ATCGGCGTGA ATTCTTTTAA TCTTGTCTCT CAAGTGTGGA GCGTTTATAA CTCTTTAAAA 780ACTTCAGAAG AAAATTTGCA AAAAAACGCC AAAATATTAT GCAACAATGG ATCGCAATCT 840GGGACAAGCC CATGCAATAG CTCTTCAGGG GGTTTGAGCA TCAGCGGGAA CGCCCAATTG 900CAAAATATTT TAAGCCCTAC TAATGGGACT ACCACTAATA CTCAAGCTAA AAGCAACGCT 960TCCAAACTAA AAGCGATGGT AATGGTGAAT AATGAAGAAG AAGCCAAAAC GACCAATTTC 1020AATCAAAGCA GTGGGCCAAC CACACAATCT TCTAACAGCA CGGTGATGGG AGCTTTAAAC 1080ACCGTATTGC AAAAT 1095(2) SEQ ID NO:216 information.

Sequence properties:

(A) length: 405 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...405

(xi) sequence representation: 216: AACCCATTCT TCACAATCAC AGCCAAACTC CTTTCCAACA CCCAAAGCGC GTTTGATCAG 60GGCATCGCTC TAAGCTCTAA TATCATTAGT GCAGTCAATA GCCTAAACCC TAGCAACAAC 120TCCCAAGAAG TCAAAGCCCAGCTCCAAAAC ACCGCGCAAT CCATGACAGA ATTGTTGCAA 180CAAATTGAAC ACAGCATCAC TAAAACCACT AGCACCACTT ACGCACAATC CTTACTCTCC 240AATCTGACCG ATGCGGTGAA TGCATCTAGC AATAATACCA CTTATGTGAG CGCTCTTGTT 300AACGCTTTAA ACACTTTAGG GGTGGGGGTT TTCCCCACCA CAACCTCAAC GCATGTGGTG 360CTAAACCCAC CGGACAAGTC GTATTCTATC CAACTAATTC CCTTT 405(2) SEQ ID NO 217 information

Sequence properties:

(A) length: 273 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...273

(xi) sequence representation: SEQ ID NO 217: GGAAGAGGAA TGAAATTAAA AAAACGAAAA GTTGCGGCTA CATTGCTAAA GCGTTTGACC 60TTGCCACTAT TGTTCACTAC GGGTTCATTA GGGGCGGTTA CTTATGAAGT GCATGGGGAT 120TTTATCAACT TCTCCAAAGT GGGTTTTAAC CGTTCGCCTA TTAACCCTGT TAAAGGTATC 180TATCCTACAG AAACTTTTGT TAACCTTACG GGTAAGCTAG AGGGGTCTGT GCATTTAGGT 240AGGGGATGGA CCGTGAATGT AGGCGGTGTT TTG 273(2) SEQ ID NO 218 information

Sequence properties:

(A) length: 2163 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2163

(xi) sequence representation: SEQ ID NO 218: ATGGAGCAGC CAGTCATTAA AGAAGGGACT TTAGCTTTAA TTGATACCTT TGCGTATTTG 60TTTAGAAGCT ATTACATGAG CGCTAAAAAT AAGCCTTTAA CCAACGATAA GGGCTTTCCT 120ACAGGGCTTT TAACGGGGCT TGTGGGCATG GTTAAAAAAT TTTATAAAGA CAGAAAA AAC 180ATGCCTTTTA TCGTGTTCGC CCTAGAAAGC CAGACTAAAA CTAAAAGAGC TGAAAAACTG 240GGCGAATACA AACAAAATCG TAAAGACGCC CCTAAAGAGA TGCTTTTACA AATCCCTATC 300GCCTTAGAAT GGTTGCAAAA AATGGGTTTT ACTTGCGTGG AGGTGGGAGG GTTTGAAGCC 360GATGATGTGA TCGCAAGTTT AGCCACGCTA AGCCCTTATA AAACCCGCAT TTATTCTAAA 420GATAAGGATT TTAACCAGCT TTTGAGCGAT AAAATCGCGC TTTTTGATGG CAAAACGGAG 480TTTTTGGCGA AAGATTGCGT GGAAAAATAC GGGATTTTGC CGAGTCAATT CACGGATTAT 540CAGGGCATTG TGGGGGATAG CAGCGATAAT TACAAGGGGG TTAAAGGCAT TGGGAGCAAG 600AACGCTAAGG AATTGTTGCA GCGATTAGGG AGCTTGGAAA AAATCTATGA AAATTTAGAC 660TTGGCGAAAA ATTTACTCAG CCCTAAAATG TATCAAGCCT TGATACAAGA CAAAGGAAGC 720GCCTTTTTAA GCAAAGAATT AGCCACTTTA GAAAGAGGAT GCATTAAAGA ATTTGATTTT 780TTAAGTTGCG CTTTTCCGAG CGAAAACCCC TTGTTGAAAA TCAAAGATGA ATTGAAAGAA 840TATGGTTTCA TTTCTACCTT AAGGGATTTA GAAAATTCCC CTTTCATTGT AGAAAACGTG 900CCCATATTAA ACAGCACGCC TATATTAGAC AATACCCCCG CCTTAGACAA CGCCCCTAAA 960AAATCGCGCA TGATTGTTTT AGAAAGCGCT GAGCCTTTGA GCATGTTTTT AGAAAAATTA 1020GAAAACCCTA ACGCTAGGGT TTTTATGCGT TTGGTTTTGG ATAAAGACAA AAAAATTCTA 1080GCCCTAGCGT TTTTATTACA AGATCAAGGC TATTTTTTAC CTTTAGAAGA GGCGTTGTTT 1140TCGCCCTTTT CTTTGGAATT TTTACAAAAC GCTTTTTCTC AAATGTTACA GCATGCGTGT 1200ATCATTGGGC ATGATTTAAA GCCTTTATTA AGCTTTTTAA AAGCCAAATA TCAGGTGCCT 1260TTGGAAAATA TCCGCATCCA AGACACTCAG ATTTTAGCGT TTTTAAAGAA TCCGGAAAAA 1320GTGGGGTTTG ATGAGGTTTTAAAGGAATAT TTAAAAGAAG ATTTAATCCC GCATGAAAAG 1380ATCAAAGATT TTAAGACAAA AAGTAAGGCG GAAAAATCAG AACTTTTAAG CATGGAATTA 1440AACGCCTTAA AGCGTTTGTG CGAATACTTT GAAAAAGGGG GGCTAGAAGA GGATTTGCTC 1500ACTTTAGCTA GAGACATTGA AACGCCGTTT GTGAAAGTTT TAATGGGCAT GGAATTTCAA 1560GGCTTTAAGA TTGATGCCGC CTTGGAAAAT ATCGTCATCG CAGGTGTTAC AAACAAACCC 1620AATGGTGCTG GCGCTATCAC ATCCACTGGT CATGTAACCG ACTATGCGGT GTTTAACAAC 1680ATCAAGGCGA TGCTACCTAT CTTGCAACAA GCGCTTACGC TTTCTCAAAG TAACCACACC 1740CTATCCACTC AGTTGCAAGC TCGAGCTATG GGATCTCAAA CAAATCGTGA ATTCGCTAAA 1800GACATCTACG CTTTAGCTCA AAACCAAAAG CAAATCCTTT CTAACGCTTC AAGTATCTTC 1860AATCTCTTTA ATTCCATTCC TAAAGACCAA CTTAAGTATT TGGAGAACGC TTACTTGAAA 1920GTGCCACATT TGGGTAAAAC CCCTACTAAC CCTTACAGAC AGAATGTGAA TTTGAATAAA 1980GAAATTAATG CGGTTCAAGA CAATGTAGCT AATTATGGTA ATCGTTTGGA TTCGGCTTTA 2040AGCGTGGCTA AAGATGTTTA TAACCTAAAA TCCAATCAAA CAGAGATCGT AACCACTTAT 2100AACGATGCTA AGAATTTGGG CCCAGGGGTT TCTAAACTTC CCTGTCGTTG TTTGGAGAAG 2160ATT 2163(2) SEQ ID NO:219 information

Sequence properties:

(A) length: 228 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...228

(xi) sequence representation: SEQ ID NO 219: ACTTCCCTGT CGTTGTTTGG AGAAGATTTA GCCAAAGAAA AACGATCCAT CGCTAAAAGC 60ATTAATTTTG GGCTGGTGTA TGGCATGGGG AGTAAGAAAT TGAGCGAAAC TTTAAGCATC 120CCTTTAAGTG AGGCTAAAAG TTACATAGAA GCGTATTTCA AGCGATTCCC TAGCATTAAA 180GATTATTTGA ATGGCATGCG AGAAGAGATT TTAAAAACTT CTAAAGCT 228(2) SEQ ID NO 220 information

Sequence properties:

(A) length: 975 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...975

(xi) sequence representation: SEQ ID NO 220: AAAGAAAAGG ATAACCCCTT GCAAAACTTT GTTTTTAATA AAAAATGGCT CATCTATTCT 60AGCCTACTCC CCTTATTTTT TCTTAACCCT TTAATGGCAG AAGACGATGG GTTTTTTATG 120GGGGTGAGTT ATCAAACTTC TTTGGCCGTT CAAAGGGTGG ATAACTCAGG GCTTAACGCC 180AGTCAAGACG CATCCACTTA TATCCGCCAA AACGCTATCG CTCTAGAATC TGCGGCGGTG 240CCTTTAGCCT ATTATTTAGA AGCGATGGGC CAACAAACGA GAGTCTTAAT GCAAATGCTC 300TGCCCTGATC CTTCTAAAAG ATGTTTGCTC TATGCAGGGG GCTATCAAAA CGGACAAAAT 360AATAACGGCG ATACAGGCAA CAACCCCCCA AGAGGCAATG TCAATGCCAC CTTTGATATG 420CAATCTCTAG TCAATAATTT AAACAAGCTC ACCCAACTCA TCGGCGAAAC TTTAATCCGT 480AACCCTGAAA ATCTTCCTAA CTCCAAAGTC TTTAACGTCA AATTTGGCAA TCAAAGCACT 540GTTATTGCAT TGCCTGAGGG TCTAGCCAAT ACCATGGACG CTTTAAACAA TGACATCACC 600AACGCTTTAA CCACGCTCTG GTATAACCAA ACCTTAACGA ATAAATCTTT TAGCACCCCT 660AGTAACACTT CTGTGAATTT TAGCCCCCAA GTCTTGCAAC ACCTTTTACA AGACGGCTTA 720GCCACAGCAA ATAATAATCA AACCATTTGC AGCACTCAAA ACCAATGCAC CGCCACTAAT 780GAAGCTAAAT CTATCGCTCA AAACGCCCAA AACATCTTCC AGGCTTTAAT GCAAGCAGGG 840ATTTTAGGGG GCTTAGCCAA TGAAAAGCAA TTTGGCTTCA CTTACAACAA AGCCCCCAAT 900GGCGGCGATT CCCAACAAGG CTATTCAAAG CTTTGCGGCC CGGGTATTAC ACCAAAACGA 960CAACACCACG CAAGC 975(2) SEQ ID NO 221 information

Sequence properties:

(A) length: 840 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...840

(xi) sequence representation: SEQ ID NO 221: TATAACCAGA TGCAAGACGT GATCAATTAC GGGGAAAGCT TGCTTAGTAA CACCGTAGCG 60TATGGGGATT TCATCACCAA TTGGGTCGCC CCCTATTTGG ATTTAAACAA TAAAGGTTTG 120AATTTCTTGC CTAATTATGG GGGGCAATTG AATGGCGCTA ATAATCAAAC CCCACAATTA 180ACCCCACAAC AAGCCCAACA AGAACAAAAA GTGATCATGA ACCAATTAGA GCAAGCCACA 240AACGCCCCCA CCCCCGCGCA AATAAACAGG ATTTTAGCCA ACCCCTATTC CCCCACGGCA 300AAAACTTTAA TGGCTTATGG GCTCTATCGC TCTAAAGCAG TGATTGGCGG AGTGATTGAT 360GAAATGCAAA CTAAAGTGAA TCAAGTCTAT CAAATGGGCT TTGCTAGGAA TTTTTTGGAG 420CATACACTCT ACATTCTAAT AACACTGAAC GGCTTTGGCG TGAAAATGGG CTATAAGCAA 480TTTTTCGGCA AAAAGCGCAT GTTTGGGCTT AGGTATTATG GTTTTTATGA TTTTGGTTAC 540GCTCAATTTG GCACAGAATC TTCTTTAGTG AAAGCCACCC TCTCTAGCTA TGGAGCGGGC 600ACAGACTTTC TTTATAATGT TTTTACCCGA AAAAGAGGGA CTGAAGCGAT AGATATAGGT 660TTTTTTGCCG GTATCCAACT TGCAGGGCAA ACCTGGAAAA CGAATTTTTT AGATCAAGTG 720GATGGCAACC ATCTTAAACC TAAGGACACT TCTTTCCAAT TCCTTTTTGA TTTGGGCATA 780ATGGACCAAA TTTTTCCAAA ATCGCTCATCTCAAAAAAGA ATCTCGTTTT TCTCAAGGGA 840(2) SEQ ID NO 222 information

Sequence properties:

(A) length: 405 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...405

(xi) sequence representation: SEQ ID NO 222: CAACCACACA AACAAAGAAA CATCGCCCAT CTACAACACG CGCAAGCTGT TATCACTTCA 60GTATTGGCTT TTTGGAGTCT TTATGCAGGG AACGCTCTCA GTTTTCATGT GACCGGTTTG 120AATGATGGAT CTAATTCTCC TTTAGGAAGA ATCCATAGAG ATGGGAACTG CACAGGATTA 180CAACAATGTT TTATGAGCAA AGAAACTTAT GATAAAATGA AGACACTTGC CGAAAACCTC 240CAAAAAGCTC AAGGCAATCT CTGTGCCTTA TCAGAATGCT CTAGCAATCA AGATAGCGGA 300TTTCCTGTTT TGGATAGTGC AGGAAAACAA GTAACTATAA CAATAACAAC GCAAACTAAT 360GGAGCTAATA AAAGTGAAAC TACTACTACT ACTACTACTA CTAAT 405(2) SEQ ID NO 223 information

Sequence properties:

(A) length: 372 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi)original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...372

(xi) sequence representation: SEQ ID NO 223: GGACTATCAA GGCAAGGAAA TGAAAGATTG GATGCCACGC TCAATTTAAA AACCGGCGTG 60CAAAGTTTTT TTAAAAAATA CATCGGGATT AGGGGGGTTT TTGCATGGGA TCTTGGGTCA 120GGAAAAGTGA ATTATCAAAG CTATAAAGAT CCTACCAACT CTTTTTTTAC CATGCTTGCG 180GTGGGTTTGG ATGTGATCAT GGAATTTCCT CTAGGGAGTT ATAAGCATTA TTTAGGGGCG 240TTTGGGGGAG CTAGGGGGGC TTTAGTTGTT TATACAGACA AGCAAAATTT CAAGTTTTTT 300AAACATTCTG TGGTTTCAGG GGGATTAGCG ATTAGTGGAG GTTGGTTGAT ATTGTTGCGG 360ACACCGCACT TC 372(2) SEQ ID NO 224 information

Sequence properties:

(A) length: 309 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...309

(xi) sequence representation: SEQ ID NO 224: CCGGTTGGGC TCTACCCCCT TGAATCCCCT TTAATTTATG AAGAAAACCA TTTGTTACCC 60ATGGGGTTTA TCCATTTAGC CTTTAGAGGG GGTGGGAGCT TGAGCGATAA AAACCAGTTG 120GGTTTGGCGA AATTGTTCGC GCAAGTTTTA AACGAAGGCA CTAAAGAGCT TGGCGCGGTG 180GGGTTTGCGC AACTTTTAGA GCAAAAAGCG ATCAGTTTGA ATGTGGATAC CAGCGCAGAA 240GATTTGCAAA TCACTTTAGA ATTTTTAAAAGAATACGAAG ATGAAGCCAT AATGCGCTTA 300AAAGAGCTT 309(2) SEQ ID NO 225 information

Sequence properties:

(A) length: 258 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...258

(xi) sequence representation: SEQ ID NO 225: TATAGCGTGT ATATCCGCTC CAACTTTTCT AAAGTGGCGC ATTTTGCGAG CGGGTATTTG 60CAAACCAAGC TCAGCACTCA AGCTAAAAGC GTTGCCTTAG CCAAAAAAAC AACTAAAGAA 120TTTATAGAAA AAGGCATGAC GCAACAAGAA TTAGACGACG CTAAAAAGTT TTTACTAGGC 180TCTGAGCCTT TAAGGAATGA AACGATCTCA AGCCGCTTGA ACACCACTTA CAATTATTTT 240ATTTGGGTTT GCCTTTAG 258(2) SEQ ID NO 226 information

Sequence properties:

(A) length: 1029 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1029

(xi) sequence representation: SEQ ID NO 226: AGACGCGCAT GGATTCTGTT GGGTTTGAAC AATCTCAAAG GGGTTTGGGT GCTTAAGGGG 60TTAAAAAAAG CGTTTAAGGA GAGGTTTTGC TCTCAAGTGT ATATCTCTTT TAATGTGGAT 120CACAATCTTT TATCCGCTCA AGTTTTAAGG GTTAAAAACC ACCGCATCAA AGAGAAATTT 180TTTAAAACTT TTGAGACTAA AGTGGAAACT AAAAATGGTG AAGTCCCCAT TCAAGCCTTA 240AAAATCGCCA GAACTTATAG CCAAAAATAC CCCTACACCT ATTTTAGCGC GATGAGTAAA 300GCTAAAGAGG TTTTATGCGA AAAGCAGGCG TTTGAACAAA TCAAACAAGA AAATCAAGAT 360TATCAGGCTT GTGAAGTCAA TCAAAAGTAT TGCGTTTATG TGGAATCTAA GGATTTTCTA 420AAGGATTTCA AGCGTTTTAA AATCCAGGAT GTGGATTTTT TGTTTTCGCC CTTTAGCCTT 480ATTTATGATT TTGTGCGCGA TAATTTAGAA AACAAGCCGT TGTTGTATCT GCTTTTAGAG 540CGTTCAAGGT TTTATTTTTT GATTGCGGAT AAAAAAGAGA TTTTTTTAGC CAAATCCGTG 600TTTTTAGAAG AGCAACCTGA AGAGTTTATA GAGAGCAAAG AAGAAGATTC TATGGGAATG 660GATAATGAAG CTGTGGATTT GTTTTTGAGT GAAATCCAAG AAGATATTGA CAGCCTTGAA 720GAAGCGATAG GCCTAGACAG CAGCAAGGAT AATAGCGAAA AAATAACAGA GGACGCTTAT 780AGTTTGATTG AAGGCATGAC GAATATCCCC TTGATTGCAG ATGTTTTGCA AGAGGGATTG 840CGTGGCGTCT ATCATTCTAG AGAGATAGAC TTTGTAGAAA AAGTGGTTGT TTTAGACAGC 900TGTCAAATCC ACCACAAGGC GTTAATGCAT TTGCAAGAAA CTTTGATGAT AGAAGTGGAT 960AGGCTCGATT TTTCTTTAGT GGAGCGGTTG AATGTTTTAG CGCGCATGGA GAATGAAAAG 1020CATGCGTTT 1029(2) SEQ ID NO 227 information

Sequence properties:

(A) length: 1260 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1260

(xi) sequence representation: 227 SEQ ID NO: ATGATTTTTG GGGATTTTAA ATATCAAAAA AGCGTTAAAA AACTCACAGC CACTAACCTT 60AACGAGCTTA AAAACGCCCT GGATTTTATC TCTCAAAATA GGGGGAAGGG GTATTTTGTG 120GGGTATCTTT TGTATGAAGC GCGCTTAGCG TTTTTAGATG AAAATTTTCA AAGCCAAACC 180CCTTTTTTGT ATTTTGAACA ATTTTTAGAA AGAAAAAAAT ACCTTGTAGA GCATCTAAAA 240GAGCATGCGT TTTACCCTAA AATCCACAGC TCTTTAGATC AAAAAACTTA TTTCAAGCAG 300TTTAAGGCCG TTAAAGAGCA TCTCAAAAAC GGCGATACCT ATCAAGTGAA TTTGACAATG 360GATTTATTGT TAAACACTAA GGCCAAACCA AAGCGCGTTT TTAAGGAAGT GATACACAAC 420CAAAACACGC CTTTTAAGGC TTTTATAGAA AATGAGTTTG GGAGCGTTTT AAGCTTTTCG 480CCGGAATTGT TTTTTGAATT AGAGTTTTTA GACACAGCGA TTAAGATTAT CACAAAACCC 540ATGAAAGGCA CGATCGCTCG CTCAAACAAC CCCTTGATAG ATGAAAAAAA CCGATTGTTT 600TTGCAAAATG ATGACAAAAA TAGAAGCGAA AATGTGATGA TCGTGGATTT ATTGCGTAAC 660GATTTGAGCC GCTTGGCCTT AAAAAATAGC GTGAAAGTCA ATCAATTGTT TGAAATCATC 720AGTTTGCCGA GCGTGTATCA AATGATAAGC GAGATTGAAG CTCAATTGCC CCTAAAAACA 780AGCTTGTTTG AGATTTTTAA GGCGTTGTTC CCTTGCGGCT CTGTGACCGG ATGCCCTAAA 840ATCAAAACCA TGCAAATCAT TGAAAGTTTA GAAAAACGCC CTAGGGGGGT GTATTGTGGG 900GCGATAGGCA TGGTTGGAGG AAAAAAAGCC CTTTTTAGCG TGCCTATCCG CATTTTAGAA 960AAAAGAGCGC ATGAAGATTT TTTGCATTTA GGGGTAGGGA GTGGGGTAAC TTATAAAAGT 1020AAAGCTTCAA AGGAATATGA AGAGAGCTTT TTAAAATCCT TTTTTGTGAT GCCCAAAATA 1080GAATTTGAGA TCGTGGAAAC GATGAGAGTT ATCAAAAGGG ATCAAAAATT AGAGATTAAC 1140AATAAAAACG CCCATAAAGA ACGCTTAATG CATAGCGCCC AATATTTTAA CTTTAATACA 1200GATGAAAATC TTTTAGACTT TGAATTAGAA GGAGAAGGGG TTTTAAGGGT TTTAATTCAA 1260(2) SEQ ID NO 228 information

Sequence properties:

(A) length: 855 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...855

(xi) sequence representation: SEQ ID NO 228: AAACAAATAA GAAAAGAACG CTTGAACAAA CTGCTTAAAA AGGGGTTTTT AGCGTTCTTT 60TTAAGCGTGT ATTTAAGGGC TGATGATCTG GTTACTTATA CGATCGCCAA AGAAGAAGAT 120CTAGGGTACC AGCGGTTTTT AGCCAAGAAG TGTTTAAGGG GTAAAACCCA CCCCCCATGT 180TTTACCGCGT CTAAAAAGCC CAAGAGGAAA CCTTTTAATA TAGATAAAAG CTCCCATTAT 240TATGGCACGA GCGTGGTGCA AATGTCATGG CTACAGAGTA GGGAAAAATT TGAAAACCAT 300TCAAAATACC GAAACATTCC TTTTGCTGAA GTCAGTTTGA TTTATGGCTA TAAACAATTT 360TTTCCTAAAA AAGAGCACTA CGGCTTCCGT TTTTATGTCT CTTTGGATTA CGCTTATGGC 420TTTTTTCTTA AAAATAAAGG CGCATTAGGC GATAGTTTGA GGGCGAGTTC GCAGATCCCT 480AAAAGCTATA GAGAAAAATT ACAAAGAAAA GAGACTTTTA TTAACGCTAT TTTTTATGGC 540GTGGGGGCTG ACTTTTTATA CAAACGCGCT TTTGGGACGC TGATTTTAGG GGTGAATTTC 600GTGGGAGAAA CCTGGTTTTA TGAAACAAAG ATTTTCAAAC AATGGGCTAA AGACTCTCTA 660AATACTTACC GCCCCAACAT GTTTCAAGTG ATGTTGAATG TGGGGTATCG CTACCGCTTT 720TCAAGGTATA AGAATTGGGC GATAGAATTT GGCGCGCGCA TCCCCTTTTT AATTAATGAT 780TATTTTAAAA CCCCTTTATA CACCCTTCAT TTCAAACGCA ATATTTCTGT CTATCTCACT 840TCAACTTATG ATTTT 855(2) SEQ ID NO 229 information

Sequence properties:

(A) length: 693 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...693

(xi) sequence representation: SEQ ID NO 229: AATACTCTTT TTTATTTCTT TTTATTACAG GCGGTTATTG TGTTAGATAG TTTTGAGATT 60TTAAAGGCTT TAAAGAGCTT GGATTTATTG AAAAACGCCC CTGCTTGGTG GTGGCCTAAC 120GCTTTGAAAT TTGAAGCTCT ACTAGGAGCG GTTTTAACGC AAAATACTAA ATTTGAAGCC 180GTTTTGAAAT CTTTAGAAAA TCTAAAAAAC GCTTTCATTT TAGAAAATGA TGATGAGATC 240AATCTTAAAA AAATCGCTTA TATAGAGTTT TCAAAGCTTG CAGAGTGTGT CCGCCCTAGC 300GGGTTTTATA ACCAAAAAGC CAAACGACTG ATTGATTTGA GCAAGAATAT TTTAAAAGAC 360TTTCAAAGTT TTGAAAATTT TAAACAAGAA GTAACCAAAG AGTGGCTTTT AGACCAAAAG 420GGCATTGGCA AAGAAAGCGC GGATGCGATT TTATGCTATG TGTGCGCCAA AGAAGTGATG 480GTGGTGGATA AATACAGCTA TCTTTTTTTA AAAAAATTAG GCATAGAGAT AGAAGATTAT 540GATGAATTGC AGCATTTTTT TGAAAAAGGC GTTCAAGAGA ATTTAAATTC CGCCTTAGCG 600CTTTATGAAA ACACCATTTC TTTAGCGCAA CTTTATGCGA GATTCCATGG AAAGATCGTG 660GAATTTTCCA AACAAAAATT GGAATTGAAG CTT 693(2) SEQ ID NO 230 information

Sequence properties:

(A) length: 693 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...693

(xi) sequence representation: 230: ATCAGCTTCA ATGCGGACTA CTTTAGGATT TGGGCGCGCG ATTTTGCCAC CGGGCAGTAT 60TCAGTCTATA CGAGCGGGCC CATGAAAGGT AATGTGCGCC CCATTAATGG CTATTCTCAA 120GGCGTGGAGC TGGAATTGTA TTACAGGCCC ATTAGAGGGT TGCAATTCCA TGCCGCTTTC 180AACTACATTG ACACTCGTGT AACTAGCCAT GGCCCTTTAA CCGACTTGAA CGGGGATGTG 240CTAAAAGGGA CTAGCTATAA CAAGCATTTC CCTTTTGTAA GCCCTTTCCA ATTCATTTTT 300GACGCTCGCT ACAATTGGCG TAAAACCACC ATTGGTATTT CTAGCTATTT TTATAGCCGT 360GCTTATAGCG GGATTAGCAA CAGCGCAGCA GGAGGCTATT ATGGGATGCA ATACTATAGT 420GGGGGGAACA ACTATGAAAG CGTTCTTAAT AGCGGTTATC AATGCGAAGC TTGGTGTATG 480ACCCAACATG AAGGGCTCTT GCCTTGCTAT TGGGTGTGGA ATATCCAAGT GAGCCAAATT 540TTCTGGGAAA ACGGAAGACA CACAGGCACA GGAAGCTTAC AAATCAATAA CATCTTCAAC 600ATGAAGTATT ATTTTACAGG GATTGGCTCT AGCCCTGCAG GCTTGCAACC TGCGCCTGGA 660AGATCGGTTA CAGCGTATTT GAACTACACT TTC 693(2) SEQ ID NO 231 information

Sequence properties:

(A) length: 804 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...804

(xi) sequence representation: SEQ ID NO 231: AGCGGTGTTG TGAAAATGAA AGACAAAAAG ATTGATGAAG AAACGAACGC CGTTTTAGAG 60GGGGAAAAAT ACACCGTGTG CGTGTCTTGT CAAATCGGCT GTCAAGTGGG TTGCTCGTTT 120TGTTTCACTC AAAAAGGCGG TTTTGTAAGG GATCTCAAAG CGAGCGAGAT TATCCAGCAA 180GCCCTACTCA TTAAAGAGGC CAATAACCTC CCCATTGAAA AAGCGCTCAA CATTGTTTTT 240ATGGGAATGG GCGAGCCTTT GAACAATTTA GATGAGGTGT GTAAAGCGGT TGAGATTTTT 300AATACCGGCA TGCAAATTTC ACCTAAAAGA GTCACCATTT CCACGAGCGG CGTGGCCGAT 360AAAATCCCCA TTTTAGCGGG CAAAAACTTA GGCGTGCAAT TAGCCATATC CTTACACGCC 420GTAGATGATA AAACGCGCTC GTCTTTAATG CCCTTGAATA AAAAATACAA CATTGAATGC 480GTTTTGAATG AAGTGAGGAA ATGGCCTTTA GAGCAGCGAA AAAGAGTGAT GTTTGAATAC 540CTTTTAATCA AAGATTTAAA CGATAGCCTG GATTGCGCTA AAAAACTTTT AAAACTTTTA 600AACGGCATTA AATCCAAAGT GAATTTGATC TTATTCAACC CGCATGAAGG CTCTAAGTTT 660GAGCGCCCTA GCTTAGAGAG CGCCAGAATG TTTGCGAATT TTTTAAACGC CAAAGGCTTA 720TTATGCACCA TTAGAGAATC CAAAGCCTTG GATATTGAAG CGGCTTGCGG GCAATTGAGG 780GAGAAAAAGC TCCAGCAGAA AATT 804(2) information SEQ ID NO 232

Sequence properties:

(A) length: 708 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...708

(xi) sequence representation: 232: AGATTGTCTG AACCCATAGA TAGATTCACA CGCATAAGGT GGTTGTTTAA AAACGATTTT 60GAAAAAATCC GCCAACAAAG GGTTTTAATC TGTGGCGTGG GGGGCGTTGG AGGCTTTGCA 120CTAGATTCTT TGTATCGTGT GGGGATAGGG CAAATCACTA TCATTGATAA AGACATGTTT 180GATGTTACCA ATCAAAACCG CCAGATTGGA TCAGAAAGGA TAGGAGAATC TAAAGTGTTG 240GTGTTGCAAG ATCTCTATAA AGGCATCCAA GCTTTAAATT GTCGCATAGA TGAAGCGTTT 300TTAAATTCAT TTAATTTTAG AGATTATGAT TACATTTTAG ATTGCATGGA CGATTTGCCT 360ATTAAAACAA GCCTAGCGAT AAAATGTCAA AATTTCGCTT ACGGGAAGTT TATCAGCTCT 420ATGGGGAGCG CGAAGCGTTT GAATCCTAAA CACATCCAAG TGGGGAGCGT GTGGGAAAGC 480TATGGCGATA AATTCGGGCG TAAATTTAGG GATTTTTTAA AAAAACGCCG TTTTAAGGGG 540GATTTTAAGG TGGTTTTTAG CCCTGAAGTC CCGCATTGCA TAGAGCTTGG AAGCTTTAAT 600GCGGTTACGG CGAGTTTTGG TTTGCAAATA GCGAGTGAAG TCGTGCAAGA TATTATCAAA 660AATGAAAGGC AATGGAATGA AAGATTACGA AGACGAATTG GAAGATTT 708(2) SEQ ID NO 233 information

Sequence properties:

(A) length: 999 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...999

(xi) sequence representation: SEQ ID NO 233: GCGAAAGCTA GGGTGCAATT CAACCGCGCG AATGAACGCC AACGCAGGGC TAAAGAATTT 60TATTATGAGG AAGTGCAAAA AGCCATTAAA GAAATCGATT CTAGCAAAAA GCACAATATT 120AATATGGAAC GCTCTAGGGC AGAAGTGAGC GAGATTTTAA ACAACACCTA TTCTAATTTA 180GACAAATACG AAGCTTATCA AGGCTTGCTT AACCCGGCGG TTTCGTATCT TTCAGGGTTG 240TTTTACGCTT TAAATGGGGA TAAGAATAAG GGATTAGGCT ATCTTAATGA AGCCTATGGG 300ATCAGTCAAA GCCCTTTCGT GGCTCAAGAC TTGGTTTTTT TCAAAAACCC TAACAGGAGC 360CATTTCACTT GGATCATCAT TGAAGATGGT AAAGAGCCGC AAAAAAGCGA ATTTAAAATT 420GATGTGCCTA TTTTTATGAT TGATTCGGTT TATAACGTGA GCGTGGCCTT GCCCAAGCTA 480GAAAAAGGGG AAGCGTTTTA TCAAAATTTC ACCCTCAAGG ACGGAGAAAA AGTAACACCC 540TTTGACACTT TAGCCTCAAT AGATGCGGTG GTCGCTAGCG AATTCAGGAA GCAATTGCCC 600TACATTATCA CTAGGGCTAT TTTATCGGCC ACTTTTAAAG TGGGCATGCA AGCGGTGGCG 660AACTATTATT TAGGGTTTGT TGGCGGGTTA GTAACTTCGT TGTATTCAGG TGTGAGCACC 720TTTGCAGACA CCAGAAACAC GAGCATTTTT GCCCATAAAA TCTACCTCAT GCGCATCAAA 780AACAAAGCCT TTGAAAGTTA TGAAGTTCGA GCCGATTCCA TTGACGCTTT TTCGTTTTCA 840TTAAAGCCTT GTAAAAGATC GCTTGAAAGC CCTAAAATCA TTGACGCTAG GGAATTGCTT 900TCAGGGTTTG TAACAGCCCC ACAAGTCTTT TGCTCTAACC GCCATAATAT TTTATATGTG 960CGCAGCTTTA AAAACGGGTT TGTTTTGAGT CATTTAAAA 999(2) SEQ ID NO 234 information

Sequence properties:

(A) length: 273 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...273

(xi) sequence representation: SEQ ID NO 234: AGGAATAAAG ATAAAAGAGA GTATTTTGAA AACGCCACCG CGCAAATTGG GGCTAAACTC 60TTGGTGTGCG ATATTAGAGA GCAGTTCTTT AACGATGTGT TGTTCAAGCC CAAATACGGC 120TATGGGAAGT ATTTCAACCC TTGCATTGAT TGCCATGCCA ACATGTTTAG GAACGCTTTT 180TATAAAATGC TTGAATTGGA TGCGGATTTT GTTTTGAGCG GGGAAGTGCT AGGCAACGCC 240CTAAATCCCA AAGGAAAGAA GCGCTCAATC AGG 273(2) SEQ ID NO 235 information

Sequence properties:

(A) length: 906 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...906

(xi) sequence representation: SEQ ID NO 235: GGGGAAGTCA TGGCTGATAG TTTAGCGGGC ATTGATCAAG TTACGAGTTT ACATAAAAAT 60AACGAGTTGC AATTGTTGTG TTTCAGGCTG GGTAAAAACA AGGATTTGTA TGCGGTCAAT 120GTCTTTAAGA TCCGTGAAGT GGTGAAATAC CATGGCAATC TCACTATCAT TAGCCACGAA 180AACAATTCGC TCGTTGAGGG CTTGATCATT ATAAGAGAGC TCACCATTCC TTTGATTGAC 240ATGAAAAAAT GGTTTTATTA TGACAGCCAA AACAAGAGCA AGGATTTACG CCCTTACAGG 300ATACAAAAAG AAAAAAGCGA AGACGATATT GTCATGATTT GTGAGTTTTC TCGCTGGACC 360ATAGGGGTTA GGATTTATGA AGCGGATAGG ATTTCGAGCA AGAAATGGAC TGAGATGGAG 420CAAAGCGCTG GGCTACGGGG ATCTGCTGGG AATAACAAAC TCGTGAGCCG CACGCGCTAT 480TTTGACGGGC GCTTGGTGCA AGTGGTGGAT ATTGAAAAAA TGCTTATAGA CGTGTTCCCT 540TGGATTGAAG ATGAAAAACA CAACGATGTA GAGACGCTTT CTAAAATCCA TTCTAACCAA 600TGCGTTTTGC TCGCTGATGA TTCCCCAAGC GTCTTAAAAA CCATGCAAAT GATTTTAGAC 660AAGCTGGGCG TCAAGCACAT TGACTTTATC AATGGTAAAA CCTTATTAGA GCATTTGTTC 720AACCCAACAA CCGATGTGAG TAATATTGAC CTGATTATTA CCGATTTAGA AATGCCAGAA 780GCGAGCGGTT TTGAAGTGAT CAACCAGGTT AAAAACACTC CTTTGACTTC AACAATCCCC 840ATTGTGGTCA ATTCTTCTAT GAGCGGGAGC TCTTATGAAA AAAATGGCAA GAATTTGAAT 900GGCCAA 906(2) SEQ ID NO 236 information

Sequence properties:

(A) length: 378 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...378

(xi) sequence representation: 236 SEQ ID NO: GCAGTAGCGT TTTGCTTACC GTATTCAAGC CCAAAGACTT CTTTAGCCAC TGAATTGCAC 60TATAGCGCTA ATGAACGCAT AGAGGCTTTT TCAAGCAATG ACGAAAAAAC AGAGAGTTTT 120GAACTGAATG AGCAAAGTTT TGAGGCGATT AAAGAGAATG CGGCGAAGTA TTCATACCTT 180AAGGTTTATT TGAAGAACGT AGCCTTAAAA GATAGTGCGC CTTTAGTGTT TGTGGATATG 240CCCGGGTTTG ATAGCCCCAT TTCAAGCCAC ACCCATGCCA TTTTGGAATA TTTGGAAAGG 300GGCGTGCATT TTGTCATTCT CACAAGCGTA GAAGAGGGTA ACCTCACTAA ACGCATGGTT 360AGGGAGTTAA AAACCTTT 378(2) SEQ ID NO:237 information

Sequence properties:

(A) length: 975 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...975

(xi) sequence representation: SEQ ID NO 237: CGGCACCCGA TTGAAAATTC GATCTGCGAT CTTAGCGAGT TGAATAATTT AAAGCCTTTG 60GGCGCGGAAA TGTTTGTGGG GTTAGACGGC ATTGATGCGA TGATAGAGGA GTGCGTTTCC 120AATTTAGTCA TTAACGCCAT TGTGGGCGTA CCCGGATTGA AAGCGAGCTT TAAAAGCTTA 180CAAAGGAACA AAAAACTAGC CCTAGCGAAT AAAGAAAGTT TAGTGAGCGC GGGGCATTTA 240TTAGACATTT CACAAATCAC GCCCGTTGAT AGCGAGCATT TTGGTTTGTG GGCGTTGTTG 300CAAAACAAGA CTTTAAAGCC TAAATCTTTA ATCATTAGCG CGAGTGGGGG GGCTTTTAGG 360GACACGCCCT TAGATCTTAT CGCTATTCAA AATGCGCAAA ACGCGCTCAA GCACCCTAAT 420TGGAGCATGG GGGATAAAAT CACCATTGAT TCAGCGAGCA TGGTCAATAA ACTTTTTGAA 480ATTTTAGAAA CCTATTGGCT TTTTGGTGCG TCTTTAAAGA TTGACGCGCT GATTGAAAGA 540AATTCTATCG TGCATGCTTT GGTGGAGTTT GAAGACAACT CTGTCATTGC GCATTTAGCG 600AGTGCGGACA TGCAATTACC CATAAGCTAT GCCATTAACC CTAAATTAGC TTCTTTGAGT 660GCTTCCATTA AACCCTTAGA TTTATACGCT TTAAGCGCGA TTAAATTCGA ACCCATTAGC 720GTGGAGCGCT ACACTTTGTG GCGTTATAAA GATTTGTTGT TGGAAAACCC AAAGCTTGGC 780GTGGTGCTGA ATGCGAGCAA TGAAGTGGCG ATGAAGAAGT TCTTGAATCA AGAAATCGCT 840TTTGGTGGCT TTATCCAAAT CATCTCTCAA GCTTTAGAAT TGTATGCTAA AAAATCTTTC 900AAGCTCTCTA GTTTAGATGA AGTGCTAGCG TTAGATAAGG AAGTTAGGGA GCGTTTTGGA 960AGTGTAGCGA GAGTG 975(2) SEQ ID NO 238 information

Sequence properties:

(A) length: 396 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...396

(xi) sequence representation: SEQ ID NO 238: GAGACGCTCG CAAGGGTTCT CAAAGTTTCA TGTTTGGCTA TGGGGCTGGC ACAGATGTGT 60TGTTTAACCC AGCTATTTTC AATCGTGAGA AACTTGCATT TGGGGTTTTT CTTGGGCGTT 120GCGATTGGTG GCACCTCTTG GGGTCCAACA AACTATTATT TTAAGGACTT AGCTGAAGAG 180TATAGAGGGA GTTTCCACCC ATCAAATTTC CAGGTCTTAG TTAATGGCGG GATCCGCTTA 240GGCACTAAAC ACCAAGGTTT TGAAATTGGC TTGAAAATCC AAACCATTCG CAATAATTAC 300TATACCGCTA GCGCGGATAA TGTGCCTGAA GGGACTACTT ATAGATTCAC TTTCCACCGC 360CCTTACGCCT TTTATTGGCG TTACATTGTA AGCTTT 396(2) SEQ ID NO 239 information

Sequence properties:

(A) length: 180 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...180

(xi) sequence representation: SEQ ID NO 239: GTCTTAAAGA ATGAAATAAG CTATAATAAG CCCATTTTGA ACACCAACGA TTATTTGAAT 60AAAGACAATA CGATGAAAGA TAGTTTTCTT TTCACTTCCG AATCAGTAAC CGAAGGGCAT 120CCTGATAAAA TGGCCGATCA GATCAGCGAT GCGGTTTTAG ATTACATGAT TGAGCGGGAT 180(2) information 240 of SEQ ID NO

Sequence properties:

(A) length: 333 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...333

(xi) sequence representation: SEQ ID NO 240: AAAACCAAAG TCGCATGCAA GACTTTAGTT TCTAATGGTT TATGCATGAT CACTGGCGAG 60TTAGAAACTT CTGTTTATGC ACCGATGCTA GAGATCGCAA GACATATGGT TAGAAAAATT 120GGCTATACAA ACGCTCTCTA TTGCTTTGAT TACAGAAGCG CGGCGGTTTT AAATGGCATT 180GGCGAGCAAA GTCCTGATAT TAATCAAGGC GTGGATAGAG AAGATGGCGA GATTGGGGCG 240GGGGATCAAG GGCTTATGTT TGGTTATGCA TGCAAAGAGA CTGAAACGCT CATGCCTTTA 300CCCATCCATT TAGCGCACCA GCTCGCTTTC GCC 333(2) SEQ ID NO 241 information

Sequence properties:

(A) length: 507 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...507

(xi) sequence representation: SEQ ID NO 241: TCCTTATCAA CACTTGCGGT TTTATTGAAA GCGCTAAACA AGAGAGTATT CCAAACCATT 60CTCAACGCAG CCAAAGACAA AAAAGAGGGA GCGATTTTAA TTGCGAGCGG GTGCTTGAGC 120GAGCGCTATA AAGATGAAAT CAAAGAATTG ATCCCTGAAG TGGATATTTT TACCGGCGTG 180GGGGATTATG ACAAGATTGA TATTTTAATC GCTAAAAAAC AAAACCAATT CAGCGAGCAG 240GTGTTTTTAA GCGAGCATTA TAACGCGCGC ATTATCACGG GATCGAGCGT GCATGCTTAC 300GTTAAAATTT CTGAGGGCTG TAACCAAAAA TGCTCTTTTT GCGCTATCCC TAGCTTTAAG 360GGAAAATTAC AAAGCAGGGA ATTAGACTCC ATTTTAAAAG AAGTAGAAGA TCTAGCCCTT 420AAAGGCTATA AAGATATGAC TTTTATCGCT CAAGATTCTA GCTCATTTTT ATCCGATAGG 480GCAAAAAGTC GGCTTGATCC AGCTCAT 507(2) information SEQ ID NO 242

Sequence properties:

(A) length: 474 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...474

(xi) sequence representation: SEQ ID NO 242: AATTTAAGGA CTATAATGCA TTATTCTTAT GAAGCCTTTT TAAAAGACAG CCTGGAGTTA 60GCTAAACAAG TGGAGCGCCT TTGCGGTATC CCAGAAGCCC TTGTGTGCGT GATGCGAGGG 120GGCATGACTT TAGTGCATTT TTTGAGTTTG CACTGGAATT TAAGGGAAGT TTATGGCATC 180AATGCGATTT CTTATGACAC CACCAAGCGA CAAAACGCCC TAAAAATTGA AAATACCCCC 240ACGATCAAAG ATCATTTAAA AACCATTTTA GTGGTAGATG AAATCGTAGA TAGCGGTAAT 300TCTTTGGAAG CGGTACTTAA AGTGTTGCAA GACAAACACC CTGATAAAAA GTTTTATAGC 360GCGAGTTTGT TCCAAAAAAC AAGCGCGAAA TACAAAGCCG ATGCGTTTTT AAAAGACGCT 420CCTGAATGGA TTGATTTCTT TTGGGAAGTG GATTTGAAAA ACTTGAAAAG CCAC 474(2) SEQ ID NO 243 information

Sequence properties:

(A) length: 681 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...681

(xi) sequence representation: SEQ ID NO 243: TCCAGCTCAT TAGAGCGATT GCCAGCAAGC CTTAAAGACG CGCGTATTTT ATACCTCTAC 60CCCTCTAGCA CCACTTTAGA GCTGATTGGC GCGATTGAAG ACTCGCCTAT TTTTCAAAAT 120TATTTTTACA TGCCCATTCA GCATATCAGC GACTCCATGC TTAAAAAAAT GCGGCGCAAC 180TCCAGCCAAG CACACCATTT AAAGCTTTTA AACGCCATGA AGCAGGTTAA AGAAAGCTTT 240ATAAGAAGCA CGATCATTGT AGGGCATCCA GAAGAAAATG AGAGCGAATT TGAAGAATTG 300AGCGCGTTTT TAGACGAGTT CCGGTTTGAC AGATTGAATA TTTTTGCTTT CAGTGCTGAA 360GAAAACACGC ATGCCTATTC TTTAGAGAAA GTGCCTAAAA AAATCATCAA CGCCCGCATT 420AAAGCCTTGA ATAAAATCGC TTTAAAACAC CAAAACCATT CTTTTAAGGC TTTGTTGAAT 480AAGCCCATTA AGGCGTTAGT GGAACATAAA GAGGGCGAAT ATTTTTACAA AGCAAGGGAT 540TTGAGATGGG CGCCTGAAGT GGATGGGGAA ATTTTAATCA ATGACAGCGA ACTAACCACC 600CCTTTAAAAC CCGGGCATTA CACGATTGTG CCTAGCGCCT TTAAAGACAA TATTTTACTC 660GCTAAGGTTT TAAGTCCTTT T681 (2) SEQ ID NO 244 information

Sequence properties:

(A) length: 324 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...324

(xi) sequence representation: SEQ ID NO 244: ATAACGAATA CAACTTTCCA ACTCCAAGGC GTTTTATTGG AATACGATTT TGAACGGCCT 60GCTATCTCTT ATACCCCTAA AAAAAGCGTT TTTAATGAGC GCTTGAAGGA TTTGAGGGAA 120AATTTTAGCG CTTCTTTATA CGCTGATTTG AAAGACAAGA TCCATCATAA CGCCTTGTCT 180AACGATGATT TAGAACGCAT GATAGCTTTT AGAGAGCAAG AATTTGAAAA GAGTTTAGAG 240GATTGGATGG GTGCATATTC TTATGATGCA ACCCTGAGGT GTTTTAGTAG CGAGCGTATC 300TATCTAGACC GGTTGGGGTG GGAA 324(2) SEQ ID NO 245 information

Sequence properties:

(A) length: 1092 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1092

(xi) sequence representation: SEQ ID NO:245: AAAAAGGTGG TTATGAATGG TTTTTGCGCT AGACTACGAG CCATAACATT TAATGAAAGA 60CTAAAAATGA AAATAGCGGT ATTACTCAGT GGGGGGGTGG ATAGCTCTTA TAGCGCTTAT 120AGCTTAAAAG AGCAAGGGCA TGAATTAGTG GGGATTTATT TAAAACTCCA TGCGAGTGAA 180AAAAAGCATG ATTTATACAT TAAAAACGCT CAAAAAGCGT GCGAGTTTTT AGGCATTCCT 240TTAGAGGTGT TGGATTTTCA AAAGGATTTT AAAAGCGCGG TTTATGATGA ATTTATCAAC 300GCCTATGAAG AAGGGCAAAC CCCTAACCCA TGCGCGTTGT GCAACCCTTT AATGAAGTTT 360GGGCTAGCTT TAGATCACGC TTTAAAATTA GGGTGTGAAA AGATCGCTAC CGGGCATTAT 420GCGAGGGTCA AAGAAATTGA CAAGGTAAGT TATATTCAAG AGGCTTTGGA TAAAACTAAA 480GATCAGAGCT ATTTTTTATA CGCTTTAGAG CATGAAGTTA TCGCTAAATT GGTGTTCCCT 540TTAGGGGATT TGCTAAAAAA GGATATTAAG CCTTTAGCCT TGAATGCGAT GCCCTTTTTA 600GGCACTTTAG AAACTTATAA GGAATCTCAA GAAATCTGCT TTGTGGAAAA AAGCTACATT 660GACACTTTAA AAAAGCATGT TGAAGTGGAA AAAGAGGGCG TGGTGAAAAA CCTACAAGGC 720GAAGTCATTG GCACGCATAA AGGCTATATG CAATACACGA TTGGCAAACG CAAAGGCTTT 780AGTGTTAAAG GCGCGTTAGA GCCGCATTTT GTGGTGGGGA TTGACGCTAA AAAGAACGAG 840TTGATTGTGG GCAAAAAAGA AGATCTCGCC ACGCATTCGC TTAAGGCTAA AAACAAATCT 900TTAACGAAAG ATTTTAAAGA TGGCGAATAC TTCATCAAGG CCCGTTACAG GAGCGTGCCT 960ACTAAAGCGT TTGTGAGCTT AAAAGATGGA ATGATTGAAG TGGAATTTAA AGAGCCTTTT 1020TACGGCGTGG CTAAAGGGCA AGCCTTGGTC GTTTATAAAG ATGATATTTT GCTTGGCGGG 1080GGCGTGATTG TT 1092(2) SEQ ID NO:246 information.

Sequence properties:

(A) length: 399 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...399

(xi) sequence representation: SEQ ID NO 246: TTGTTTAAAA CCAATGGGAT AAGTGTGGGG GAATACACTC ATTTTAGCGA AGATATAGGC 60AGTCAATCGC GTATCAATAC CGTGCGTTTG GAAACTGGCA CTAGGTCAAT CTTTTCTGGG 120GGTGTCAAAT TTAAAAGCGC TGAAAAACTA GTTATCAATG ATTTTTACTA TAGCCCTTGG 180AATTATTTTG ACGCTAGGAA TGTTAAAAAT GTTGAAATCA CCAGAAAATT CGCTTCTTCA 240ACCCCAGAAA ACCCTTGGGG CACATCAAAG CTCATGTTTA ATAATCTAAC CTTGGGTCAA 300AATGCGGTCA TGGACTATAG TCAATTTTCA AATTTAACCA TTCAGGGGAT TTTATCTACA 360ATCAAGCGAT ATCATTTGAC GAAGGGTTTT TTTACCCCC 399(2) SEQ ID NO 247 information

Sequence properties:

(A) length: 246 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...246

(xi) sequence representation: SEQ ID NO:247: ATGAAAAAAA CCCGTATCCG GAAGAAGTCA GCTTTAATGAGATAGCGTTT TTAGCGCCAT TGTGCCTTTA GAAGATTTAACATGCCCTAA AGGCTTTACA AGCTACGCTA AAGACAACGAAGTTGGAACA GATCGCAAAA GGATTCATCC CTAGGGGGTAATGTTT (2) SEQ ID NO:248 information

Sequence properties:

(A) length: 315 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...315

(xi) sequence representation: SEQ ID NO:248: TGGACTCTAG CCAAAATTCG TTGCGTTAAA AACTTTAAGGGAAAAAATCA AAGAATCCCC TAACGATTCA AACGCTATCAGAAACAGAGT TAGAGCGCGC TACAGAAAAT TTGAGTCAAACGGAATGAAA ATTATACGCA AAAAGCGTTG GAGTATAGGGGAGAGCTTTA TTGTAGATGA AAAAAACCCG TATCCGGAAGCTGTTGGGCG GAATT (2) SEQ ID NO:249 information

Sequence properties:

(A) length: 852 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...852

(xi) sequence representation: SEQ ID NO:249 AGACCTTTGG CACTCATCAT GTGGTGGCGA AATATAGACA ATCGTATCTC TATTAAGCGC 60GTTGTAAACA AGCCCCCAAG AGGCCTTGGC AAGATCACTC AAGAATGGAT TTTTTCTCTT 120TTAGATGAAG AGGGTTTGAA TTTAGAAGAA GCGCTAAAAA TTGGGGCGTT TAAAGACAAA 180CTCAACCCTA AAAACGAATA CGCTTTAAAG AAATTCACCG CTATGATAGG GCGTTTGAGG 240GAGGCTTTTG AAATTTCAGT AGAGAAGTTT TGCGAGCGGT TTTTAGAAGA GACTAACCTT 300TTAAAAAGCT ATGAAAAAGA AGACAATTAC GAAGAAAGAG AGGGCTTTGT TAAAGAGCTT 360TTAAGTTTAG TGAAAGAGCA TTTTAAAACT AACCCCACGC ATTCTTTACT GGATTTTTTG 420AATGAAAGCG CACTGGATGT CCATAATACA GAAAACGCGC AAAAAGTGAG TTGCATGAGC 480GTGCATATGA GTAAGGGCTT AGAGTTTAAG CATGTGTTTG TGATCGGGTT AGAAGAGGGG 540TTTTTCCCGC ATAGGGGGTT CAATCAAGAA AGCGATTTGG AAGAAGAAAG GCGCTTGGCT 600TACGTGGCGA TCACTAGGGC TAAAGAAGAA TTACAACTTT CTTATGTCAA AGAGCGTTCG 660TATTTTGGGA GGAAAATTTC TTGCTCGCCC TCTGTGTTTT TAGAAGAAGC CCAGTTGCTC 720CAACAAGACA AGCCTCCTAA ACAAAATCAC CAAAAAGATA CGCCCATTAA AGTGGGGGAT 780TTGATCAAAC ATAAGATTTT TGGCACCGGG GAGGGTTTTA GGCGTAGAAA AAGGCTTGCA 840GCGGTTTGTG CT 852(2) SEQ ID NO:250 information

Sequence properties:

(A) length: 726 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...726

(xi) sequence representation: SEQ ID NO 250: GATGGGTCAA AAAAGATGAA GTCAAATAAA AAGTCCAATC ATTTAAGAGC GATTTATAGG 60GCTTTAGTGA TCGCTATAGG CTTAGCCGTT ATCATTGTTT TCAATTATTT TAACCGCAAA 120AACAATAACG CCCGCTCCAG CCGTAGGGCT TGTTCGTGTT TTTTTCCCCC CACCGGGGTT 180AATTTAGAAA AAATAGGTTC CTTTGACACG GGCGCTAAAC TCATTGTCTT AAACCACCAA 240AGCTTACTAG ACATTATTTA TTTAGAAGCC TACCACCCTA GTAATATTTG CTGGATCGCT 300AAAAAAGAGC TGGGCGAAAT CCCTTTTTAT GGGCATGCTC TAACGGATAC CGGAATGATC 360TTAATTGACA GAGAGGATAA AAAGGGGATA GTGAGCCTTT TGAAAGCATG TAAAGAAAAG 420CTAGATCAAA ACCGCCCTTT AGTGATTTTT CCTGAAGGCA CTAGAGGCAA AGGAGGAGAA 480AAATTCCTCC CCTTTAAGCA AGGGGCTAAA ATCATCGCTG AAAAATTCCA GCTCAAAATC 540CAGCCCATGG TGTTAATCAA TTCCATTAAA ATCTTTAATT CCAAGCCCCT AGAAGCTTAT 600AAAGCGCGCA CCCGTTTGGT CATGCTAGAA AGCTATACGC CTGATTTTAG CTCGCCCACC 660TGGTATGAAG AATTACAAGA ACGCATGCAA AAAGAATATT TAAAACACTA CCACGAACTA 720AACGCA 726(2) SEQ ID NO 251 information

Sequence properties:

(A) length: 831 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...831

(xi) sequence representation: SEQ ID NO:251: GTCATGAAAA CTTCTAACAC AAAAACCCCT AAACCCGTTT TAATCGCCGG GCCATGCGTC 60ATTGAGAGTT TAGAAAATCT AAGAAGTATC GCTATTAAAT TACAACCCCT AGCCAACAAC 120GAGCGGTTGG ATTTTTATTT TAAAGCGAAT TTTGATAATG CTAACCGCAC GAGTTTGGAA 180AGTTACAAAG AACCTGGTTT AGAAAAAGGC TTAGAAATGT TACAAACTAT CAAAGATGAA 240TTTGGTTATA AAATTTTAAC CGATGTGCAT GAGAGCTATC AAGCAAGCGT GGCAGCCAAG 300GTAGCGGATA TTTTACAAAT CCCGGCGTTT TTGTGCCGCC AAACGGATCT GATTGTAGAA 360GTGAGCCAAA CTAACGCCAT TGTCAATATC AAAAAAGGGC AATTCATGAA CCCAAAAGAC 420ATGCAATATT CCGTTCTAAA AGCCCTTAAA ACAAGGGATA GTAGCATTCA AAGCCCCACT 480TATGAAACAG CGTTAAAAAA TGGCGTGTGG CTGTGTGAAA GGGGGAGCAG CTTTGGGTAT 540GGGAATTTAG TGGTGGATAT GCGCTCTTTA AAAATCATGC GAGAATTTGC CCCTGTGATT 600TTTGACGCTA CCCATAGCGT GCAAATGCCA GGGGGAGCGA ACGGGAAAAG TTCAGGAGAC 660AGCTCTTTTC CCCCTATTTT ACCCAGAGCG GCGGCGGCGG TGGGGATTGA TGGGCTGTTC 720GCTGAAACGC ATATTGATCC TAAAAACGCC CTAAGCGATG GAGCAAACAT GCTAAAACCT 780GACGAGCTAG AACACTTAGT AACCAACATG TTAAAAATCC AAAATTTATT T831 (2) SEQ ID NO:252 information

Sequence properties:

(A) length: 939 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...939

(xi) sequence representation: SEQ ID NO 252: CAAAGAGATC ATGGCGTTTT GTATTTGCTT AATAACACTA TAATAAAATT TTTAATAAGG 60AGATACATCA TGTTAGAAAA TGTCAAAAAA TCCCTTTTTA GGGTTTTGTG CTTGGCCGCG 120TTGTGTTTAG GGGGGCTAAT AGCAGAGCAA GACCCTAAAG AGCTTGTCAA TTTGGGAACA 180AAGAGCTACA AAGAGCAGGA TTTCACTCAG GCTAAGAAAT ATTTTGAAAA AGCTTGCGAT 240TTGAAAGAAA ATAGCGGGTG TTTTAATTTA GGGGTGCTTT ATTATCAAGG GCATGGGGTG 300GAAAAGAATT TGAAAAAAGC CGCTTCATTT TACTCTAAAG CTTGCGATTT AAATTACAGC 360AATGGGTGTC ATTTGCTAGG GAATTTATAT TATAGCGGGC AAGGCGTGTC CCAAAACACC 420AACAAAGCCT GGCAATACTA CTCTAAAGCG TGCGATTTGA AATACGCTGA AGGGTGTGCG 480AGCTTAGGGG GGATCTATCA TGATGGCAAA GTGTTTACTA GGGATTTTAA AAAAGCGGTG 540GAATATTTCA CTAAAGCTTG CGATTTGAAC GATGGCGATG GTTGCACGAT ATTAGGGAGC 600TTGTATGATG CAGGCAGAGG CACGCCTAAA GATTTGAAAA AAGCGCTCGC TTCGTATGAT 660AAAGCTTGCG ACTTAAAAGA CAGCCCAGGG TGCTTTAACG CAGGGAACAT GTATCATCAT 720GGCGAAGGTG CGGCGAAGAA TTTTAAAGAG GCCCTCGCTC GTTATTCTAA GGCATGCGAG 780TTGGAAAATG GCGGAGGGTG TTTCAATTTA GGGGCTATGC AATACAATGG CGAAGGCGCA 840ACAAGGAATG AAAAGCAAGC CATAGAAAAC TTTAAAAAAG GCTGTAAATT AGGCGCTAAA 900GGGGCATGCG ATATTCTCAA GCAGCTCAAA ATCAAAGTT 939(2) SEQ ID NO 253 informative NO

Sequence properties:

(A) length: 1590 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1590

(xi) sequence representation: SEQ ID NO 253: ATGAGCAGCG GGTTAATTTA CATTTCATTA GAAGTCTTGG TAGCGTGTTT GATCACCGCT 60CTAATCATGT ATTATGTGAT GAAAAAGATC TATTACGCTA GAGGGCAAGC CATTTTAAAA 120GGCGCTTCAG CCAAAGCTAA ATTAATGGAA TTTCAAGCGA AATCTTTCGT GGAAGCTGAA 180GAAATGCGCA TGAAAAGCCA AGAATGCAAG TTGCAACAGC AATATGAAAA TAAGAATTTG 240CAACTCCAAA CCCATTTTGA TAAAAAAGAA GCGCATTTGA AGCATTTAGA AGCGCAGCAC 300AAAGAATTTG TAAGAGATGA AAAACGCTAT TTGGAAAAGG AAAAAAAAGA GCTTGAAAAA 360GAACGCCAAA TTTTAGAACA AGAGAGGGAA AATTTTAAAA AACAGCGCGC CATTTGTAAA 420GAAGCTCAAG CCAAAGCGCT AGATGCGATG CTCAATTACA TGGCTTATAC CAAAGATGAA 480ATTAAAAGCA TGATCTTAGA GCAACTAGAA GAGGAACTAG AAGCGCAAAA AAGCGCCTTG 540ATCAGGCGTT ATGAAAAAGA AGCCAAAGAA GAGGGTAAGA AAAAATCGTA TGCCATTTTA 600GCGGAAGCGA CAGCCCGTTT TGCGGGCGAT TATGCGACAG AGAATTTAAC AAGCCGTATC 660GCTTTGCCTT GCTCAGATTA TGTGGGTCGT GTGATAGGCA AAGACGGGAA AAACATTGAA 720GCGTTTAAAA AGATTAGTGG GGTGGATATA GAATTTAGCG AAGACAGTAG CGAATTGTGC 780TTGTCCAGTT TCAATATTTA TCGGCGTGAA GTGGCGAGCG AGACGATTAA AATTTTAATA 840GAAGACGGCC GTATCCAGCC TAACAGGATT GAAGAGGTTT ATCATAGAGT CGCGCGCAAC 900ATGGAAAAAG AATTGCTTTC TGAAGGAGAG AGCGTGGTGC TAGAATTAGA GCTTGGAACT 960ATGGAAGATG AGCTTAAAAT TTTAATAGGC AAAATGCGTT ATCGCTTTAG TTTTGGGCAA 1020AACGCTTTAC AGCATTCTAA AGAAGTCGCT CTTTTAGCCG GCTTGATTGC AGAACAGCTT 1080GGGGGGGATA AAAAACTCGC CAGAAGAGCC GGTATTTTGC ATGATATTGG TAAAGCGCTC 1140ACTCAAGAGC TTGGGAGAGA CCATGTGAAT TTAGGGGTTG AGGTGTGCAA GCGCCATAAA 1200GAAGACCCGG TTGTGATCAA TGCGATTTAT GCCCACCATG GGCATGAAGA AATCATGAGC 1260GTGGAGTGCG CGAGCGTGTG CGCGGCTGAT GCGCTTTCTG CAGGGCGTCC GGGCGCTAGG 1320AGAAAGAGCG ATGAAGAATA CGCTAAACGC ATGCAAGCTT TAGAAGAGAT CGCGTTAGAA 1380TTTGATGGGG TGGAAAAGGC GTATGCGATG GAGAGCGGGC GAGAACTAAG AGTGATTGTC 1440AAATCCAACC AAGTCAGGGA CAATCAAGTG CCTATTATTG CTAGAAAGAT CGCTAAAAGG 1500ATAGAAGAGA GCACTCAGTA TGTGGGCGAA GTGGGCGTGC AAGTGGTGCG AGAAAATCGT 1560TTCAAAACGA CCGCTACGCT CAAGCAATGA 1590(2) SEQ ID NO 254 information

Sequence properties:

(A) length: 750 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...750

(xi) sequence representation: SEQ ID NO 254: ATGAAAAAAG GTAGTTTAGC AATCGTTTTA GGATCGTTAC TAGCAAGTGG GACGTTTTAT 60ACGGCTCTAG CTGATGGAAT GCCTATGAAG CAACAGCACA ATAACATGGG TGAGTCTGTG 120GAGTTGCATT TCCACTATCC TATTAAAGGC AAACAAGAGC CTAAAAATAA CCATTTAGTT 180GTCTTAATCG ATCCTAAGAT AGAGGCTAAT AAAGTTATCC CTGAAAATTA TCAAAAAGAA 240TTTGAGAAGT CTTTGTTCCT CCAACTGAGT AATTTTTTAG AGAGAAAGGG CTATAGCGTT 300TCGCAATTTA AAGATGTTAG CGAAATCCCT CAAGACATCA AAGAAAAAGC GTTGCTCGTT 360TTACGCATGG ATGGGAATGT GGCTATCTTG GAAGATATTG TAGAAGAGAG CGATGCGCTC 420AGTGAAGAAA AAGTGATAGA CATGTCTTCA GGGTATTTGA ATCTGAATTT TGTTGAGCCA 480AAAAGTGAAG ACATTATCCA TAGTTTTGGT ATTGATGTTT CAAAGATTAA GGCTGTGATT 540GAAAGGGTGG AATTGCGGCG TACCAATTCT GGAGGTTTTG TCCCCAAAAC TTTTGTGCAT 600AGGATCAAGG AAACCGACCA TGACAGAGCC ATTAAAAAGA TCATGAATCA AGCCTATCAC 660AAAGTGATGG CGCATATCAC CAAAGAATTA AGCAAAAAAC ACATGGAACG TTATGAAAAA 720GTTTCTAGTG AAATGAAAAA GCGAAAGTAG 750(2) SEQ ID NO 255 info 255

Sequence properties:

(A) length: 357 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...357

(xi) sequence representation: SEQ ID NO 255: ATGCAAAACA CCTTTAACTA CACCAACAAC GCTTTGAAAA ACAATGCTAA ATTAACCCCC 60ACTGAAATGC AAGCCGAACA ATACTACCTC CAATCCACCC TTCAAAACAT TGAAAAAATA 120GTCATGCTTA GCGGTGGCGT TGCGTCTAAC CCTAAACTAG TCCAAGCGTT AGAAAAAATG 180CAAGAACCCA TTACTAACCC TTTAGAATTG GTAGAAAACT TAAAAAATTT AGAATTACAA 240TTCAGCCAAT CTCAAAACAG CATGCTTTCT TCTTTGTCTT CTCAGATCGC TCAAATTTCA 300AATTCTTTGA ACGCGCTTGA TCCCAGCTCT TATTCTAAAA ACGTTTCAAG CATGTAT 357(2) information of SEQ ID NO 256

Sequence properties:

(A) length: 945 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...945

(xi) sequence representation: 256: ATGGACTTAG ACAAACTCAA AGATTATAGG GCTTTAAGAA ACGCTATTTT AAGGCTATTG 60CCTTATTTAG ATAGCGGTAT TACAGAGCTA ATTATGAATA AAGAAAAAGA AATTTGGCTC 120TATAAGCTTA ATGGAGTAAG AGAAAAAGTC TTTGATGAAA ATTTAGACAA AGCCTTTATT 180CTGGGGTTTG GGGAACAATT AGCGAGTTTT AGAGATTTGT TTTTTAATGC TAATTACCCC 240ACCCTTAATA CTTCCATTCC TACTTCTAGA TACAGAGTGA GCATGAACCA CTTTGCTATT 300AGTGCGGATA ATGAATTGAG TTTGAATATT AGAGTGCCAA GTGATAAAAA GTTTGATTTA 360AAAGCTTTCA AGCTTTCTAG TATCTGTCAA TACGATTATG AGTATTTAAA AAACTTAATG 420ATTGATGGCA AAAACTTACT CATTAGTGGA GGCACAGGCA GTGGAAAAAC GAGTTTTTTA 480AACGCTCTAA TTGAGTTTAT CCCCAAACAC ACACGAATAG TAAGCGTTGA AGATAGCGAA 540GAATTAGATT TAAGAGCGTT TGAAAATCAT AAATCCTTGT TAGTGGATAA AACTGAAAGC 600TCTAAATTTA CATATGAAAA CGCCTTGAAT ATGGCAATGA GAATGTCTCC TGATAGGCTT 660ATGGTAGGCG AGATTGACAC ACGAAATTCC ATGCTCTTTT TAAGATTTGG AAACACTGGG 720CATAAAGGCA TGGTTTCTAC TTTACATGCA GATAGTGTGC ATGGGGTTAT AGAGGCGATT 780GCTTTAAATT TACAAATGAA TAAAAGTGGT TTAGATGTCA ATGTAGCAAA AAAATTCTTT 840AAAAGCAGTG TGGATGTTGT CGTTCAAATT GTATTAGATA AAGCCACTAA CACCAGATAC 900ATTCAAGAAA TCTTACCAGC AAAAGATTTA AGAGATAGTC TATGA 945(2) SEQ ID NO 257 information

Sequence properties:

(A) length: 435 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...435

(xi) sequence representation: SEQ ID NO 257: ATGAATATAT CGGTTAACCC CTATTTAATG GCGGTCGTTT TTGTAGTGTT TGTGTTGTTG 60TTGTGGGCGA TGAATGTTTG GGTGTATAGG CCTTTGTTGG CTTTTATGGA TAACAGACAG 120GCAGAGATAA AGGACAGCTT GGCTAAAATC AAAACGGATA ACACCCAAAG CGTGGAGATT 180GGCCATCAAA TTGAGACTCT TCTTAAAGAA GCCGCTGAAA AGCGCAGGGA AATGCTAGCA 240GAAGCGATTC AAAAAGCTAC AGAGTCTTAT GACGCTGTGA TCAAGCAAAA GGAGAACGAA 300CTCAATCAAG AGTTTGAAGC GTTCGCAAAG CAATTACAAA ATGAAAAACA AATCTTAAAA 360GAGCAATTGC AAGCGCAAAT GACGGTATTT GAAGACGAGT TAAACAAGCG TGTGGCTATG 420GGTTTAGGGA GTTGA 435(2) SEQ ID NO 258 information

Sequence properties:

(A) length: 276 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: isnot

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...276

(xi) sequence representation: SEQ ID NO 258: ATGGCTAGTG GCCTTTTTGA AAACGATGAA ATCAAAAACA ACAAAGCGCG AGATTTTTTT 60TATAGCCATA GCTCCCTTAT TGTCTTTTTC CTCTTACTGC TTGGGTTTGG GTATTATTTA 120GGGAAGTTGC TTTTTGGGGG TTCTTCTTTA GAGGTCTATT TGGATTTAAG AGACAAGCAT 180GAACGATTGC AACAAGAAAT CACCGAATTG CAAAGCAAGA ATGTGCGCTT GCAAAAGCGT 240TTGTTTGAGT TGAGGGAATT ACGGCCTAGA GATTAG 276(2) SEQ ID NO 259 information

Sequence properties:

(A) length: 900 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...900

(xi) sequence representation: SEQ ID NO 259: ATGAAAAAAA ATATCTTAAA TTTAGCGTTA GTGGGCGCGT TGAGCGCGTC GTTTTTGATG 60GCTAAGCCGG CTCATAATGC GAATAACTCT ACGCATAACA CGAAAGAAAC GACTGATGCT 120TCAGCAGGCG TGTTAGCGAC AGTGGATGGC AGACCCATCA CCAAAAGCGA TTTTGATATG 180ATTAAGCAAC GAAATCCTAA TTTTGATTTT GACAAGCTTA AAGAGAAAGA AAAAGAAGCC 240TTGATTGAGC AAGCTATCCG CACCGCGCTTGTAGAAAATG AGGCTAAGGC AGAAAAGCTT 300AATCAGACTC CAGAATTTAA AGCGATGATG GAAGCGGTTA AAAAACAGGC TTTAGTGGAA 360TTTTGGGCTA AAAAACAGGC TGAAGAAGTG AAAAAGATCC AAATCCCAGA AAAAGAAATG 420CAGGATTTTT ACAACGCCAA TAAAGATCAG CTTTTTGTCA AGCAAGAAGC CCATGCTAGG 480CATATTTTAG TGAAAACCGA AGATGAAGCC AAAAGGATTA TTTCTGAGAT TGACAAACAG 540CCAAAGGCTA AAAAAGAAGC CAAATTCATT GAGTTAGCCA ATCGGGATAC GATTGATCCT 600AACAGCAAGA ACGCGCAAAA TGGCGGTGAT TTGGGGAAAT TCCAAAAGAA CCAAATGGCT 660CCGGATTTTT CTAAAGCCGC TTTCGCTTTA ACTCCTGGGG ATTACACTAA AACCCCTGTT 720AAAACAGAGT TTGGTTATCA TATTATCTAT TTGATTTCTA AAGATAGCCC TGTAACTTAT 780ACTTATGAGC AAGCTAAACC TACCATTAAG GGGATGTTAC AAGAAAAGCT TTTCCAAGAA 840CGCATGAATC AACGCATTGA GGAATTAAGG AAGCACGCTA AAATTGTTAT CAACAAGTAG 900(2) SEQ ID NO 260 information

Sequence properties:

(A) length: 918 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...918

(xi) sequence representation: SEQ ID NO 260: ATGATAAAGA GTTGGACTAA AAAGTGGTTT TTGATTTTAT TTTTAATGGC AAGCTGTTTT 60GGTCATTTGG TGGCTACAAC CGGTGAGAAA TATTTTAAGA TGGCTAATCA AGCCCTTAAG 120AGAGGGGATT ACCATAGAGC GGTGGCTTTT TATAAGAGGA GCTGTAATTT GAGGATGGGG 180GTTGGTTGCA CGAGTTTAGG CTCTATGTAT GAATATGGCG ATGGCGTGGA TCAGAATATT 240TCAAAAGCCG TTTTTTATTA CAGAAGAGGG TGTAATTTGA GGAATCATCT CGCTTGCGCG 300AGTTTAGGCTCTATGTATGA AGATGGCGAT GGCGTGCAAA AAGACTTTCC AAAGGCTATC 360TATTATTATA GGAGAGGGTG CCACTTAAAA GGTGGGGTGA GCTGCGGTAG TTTGGGTTTT 420ATGTATTTCA ATGGTACGGG CGTTAAACAA AATTACGCCA AAGCCCTTTC TTTTTCTAAA 480TACGCTTGCA GTTTGAATTA TGGCATTAGT TGTAACTTTG TAGGGTATAT GTATAAGAGC 540GCCAAAGGCG TGGAGAAGGA TTTGAAAAAA GCCCTTGCGA ATTTTAAAAG AGGGTGCCAT 600TTAAAAGACG GGGCGAGCTG TGTGAGCTTG GGATACTTGT ATGAAGCCGG TATGGATGTC 660AAACAAAATG AAGAGCAGGC TTTGAATCTT TATAAAAAGG GTTGCTCTTT AAAAGAAGGG 720AGCGGTTGTC ATAATGTGGC GGTGATGTAT TACACGGGTA AGGGAGCTCC AAAAGATTTG 780GAGAAAGCCA CTTCATATTA TAAGAAAGGG TGCGCTTTAG GCTTTAGTGG TAGTTGTAAG 840GTGTTAGAAG TGATTGGCAA GGAGTCTGAT AATTTGCAAG ATGACGCGCA AAACGACACG 900CAAGATAGCG TGCAATAA 918(2) SEQ ID NO 261 information

Sequence properties:

(A) length: 1509 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1509

(xi) sequence representation: 261: TTGAAAATCT TTTTAGTTAT TCTAAGCGTC TTTTTTTTTA ATGGGTGTTT TGGGCTAGCC 60TATAAGACTC CCATTTCAAA CCCCCCTATC TCTTATGACC CCTACACTAC CACCATTGGG 120AGCTTGTATG CTAAAAATTT AAAAGAAAAC CCTAAACATA GTGCGGCCAT TCTTTTAGAA 180GACGGCTTTG ATGCCTTGTT GCACAGAGTG GGTCTTATTA GAATGAGCCA AAAAAGCATT 240GACATGCAAA CTTATATCTA TAAAAACGAC CTTTCTTCTC AAGTGATCGC TAAAGAACTT 300TTAAACGCGG CCAATCGTGG GGTAAAAGTG CGCATCCTTT TAGATGACAA CGGGTTAGAT 360TCAGATTTTT CAGACATCAT GCTTTTAAAT TTCCACAAAA ACATTGAAGT GAAAATCTTT 420AACCCCTACT ATATCCGCAA TAAAGGCTTG CGTTATTTTG AAATGCTTGC GGATTATGAA 480CGCATTAAAA AACGCATGCA CAACAAGCTT TTCATCGTGG ATAATTTCGC TGTCATTATA 540GGGGGGCGCA ACATTGGGGA CAATTATTTT GATAACGATT TAGACACGAA TTTTTTAGAT 600TTAGACGCTT TGTTTTTTGG GGGGGTTGCT TCAAAGGCCA AAGAAAGCTT TGAAAATTAT 660TGGCGATTCC ACCGCTCTAT CCCTGTTTCA TTATTAAGAA CCCATAAAAG ACTCAAAAAC 720AACGTTAAAG AAATCGCTAA GCTCCATGAA AAAATCCCTA TCAGCGCTGA AGACGCAAAC 780GAATTTGAAA AAAAAGTCAA TGATTTTATA GAACGCTTCC AAAAATACCA ATACCCCATT 840TATTATGGGA ATGCCATTTT TCTAGCCGAT TTGCCCGCCA AAATTGACAC GCCCTTGTAT 900TCGCCCATCA AAATCGCTTT TGAAAAAGCC CTTAAAAACG CTAAAGACTC CGTTTTTATC 960GCTTCATCGT ATTTTATTCC AGGTAAAAAG ATAATGAAAA TCTTTAAAAA TCAAATTTCT 1020AAGGGGATTG AATTGAATAT TCTTACCAAT TCCCTTTCAT CTACGGACGC TATCGTGGTC 1080TATGGGGCGT GGGAAAGGTA TCGCAATAAA TTAGTGCGAA TGGGCGCGAA TGTCTATGAA 1140ATACGAAACG ATTTTTTCAA CCGCCAGATT AAAGGGCGCT TTAGCACCAA ACATTCCTTA 1200CACGGCAAGA CAATTGTTTT TGACGATGCC CTAACGCTTC TAGGGAGTTT TAATATTGAT 1260CCGCGCTCTG CATATATTAA CACTGAAAGT GCGGTCTTGT TTGACAACCC GTCTTTTGCC 1320AAAAGGGTGC GTTTGTCGCT TAAAGATCAT GCCCAACAAT CATGGCATTT AGTCTTGTAT 1380CGGCATAGAG TGATTTGGGA AGCTACAGAA GAAGGCATCT TAATCCATGA AAAAAACTCG 1440CCTGATACCT CTTTCTTTTT GCGTTTGATT AAAGAATGGT CTAAAGTCCT TCCTGAAAGA 1500GAACTTTAA 1509(2) SEQ ID NO 262 information

Sequence properties:

(A) length: 510 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...510

(xi) sequence representation: SEQ ID NO 262: TTGAAAAATC TCTCAACACT TCTGGTGTTT TTATTCTTTT GTTTGGGGTG TGTGAGCAAT 60TTTAATGAAG ACACTTACAC GCTAGACTTA GTTTTAGAAA AAAAGATCCA AGCCAGTAGG 120AAAGGCGAAA TCACCCAAGA TAATGTGCCT ATCATCACGG CTATCGCTAC GCATTTAAAC 180GATGTGGATA GCGGCACTTA CTACGATCAT GAGTATTTTT TAGTGGAGAT TTTCACGCAA 240AATAACGACT GGATAGATGA TGGCTATATT TCTTATGAAC TTTTTGGCAC AAAACCTACA 300GGATCAGAAC CTTTATGGGT GCGAGAGATT ACAAGAGATG AATTTGATGG CATTTTAGAA 360ACCACGAACC GGTGGAGCCG AGCCTTTTTG ATCGCTTTTG ACAAATTGGA TTATTTAGCG 420GTGCAAGAAG CCAAACTAGA GCTTGATGCC TATAGTTTAG GCAAAATTGT TTTTAATTTC 480GCTTACCAAG TCCCCTTACC TCAATTTTAA 510(2) information SEQ ID NO 263

Sequence properties:

(A) length: 1536 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1536

(xi) sequence representation: SEQ ID NO:263: ATGAAAAAAC TTCTTTATAC CATGCTCGCG CTTCTTTTAA TCGGCCTTTT AACGGCCTAT 60CTTATCCTTT TTACAGAATG GGGGAATAAG ATCATCGCTT CGTATATAGA GAAAAAAATC 120AATCCGAACG AGCGTTATTT GAGCGTTAAA ACCTTTAAAT TGAGATTCAA CTCTTTGGAT 180TTCAAAGCTC AAGCCAACGA TGATTCCACG CTCATTCTTA AGGGGGATTT CTCGCTTTTA 240ACGCAAAGCG TAAATTTGGA TTACCACATA GACATTAAAA ATTTACGCTC TTTTAAGGAT 300TTGATACCCT ACCCCTTAAG AGGGGCTATT GTTACTTCTG GGAATATCAA AGGGCATAGA 360AAAGCCCTTG TAGTTCAAGG CGTCTCCAAT GTCGCTCAAT CCCACACTGC CTACAACGCC 420CTTTTAGATG ATTTCAAGCT TTCTCACTTA AGTTTGAACG CAAAAGACGC CAATTTAGAA 480GATTTGCTTT ATTTAATCAA CCGCCCCGCT TATGCGAACG CAAAAGTGTC CTTACAAGCG 540GATTTTAACT CTCTAAAGCC CTTAGAAGGG CATTTGATCC TAACAGCTAA TAACGCTTTA 600 GATTTGCTTT ATTTAATCAA CCGCCCCGCT TATGCGAACG CAAAAGTGTC CTTACAAGCG 540 600ATCAATAACG CCCTAATCAA TCAAATCTTT CATTTAAACC TTAAAGACAC GCTCGTTTTC 660AACCTCTCGC ACTCAAGCGA TTTTAAAGGA AACAAAGCCA TCAGCGATAC CACCCTAACT 720AGCCCTTTAG TTAATTTCAC AGCCCTAAAA AGCGAATATT CTTTCCCTGC TTTAAAACTC 780AACGCCCCCT ACACTTTAGA AATACCCCAT CTAGCCAAAC TCCAAAACAT TACCAACCAC 840CCCTTAAAAG GGAGCTTGAC TTTAAAAGGC GATATAGAGC AAAGCCCTAA ACTCTTAAAA 900GTCAGTGGCC ATTCAAATTT ACTAGACGGC GCGCTAGACT TCACGCTTTT AAATAAAGAT 960TTGAAAGCCC GTTTTTCCAA TATTTCCACT TCAAAAGCCT TAGATTTATT CCATTACCCT 1020AAATTTTTCC AATCCATTGC AGACGCTAAC TTGGATTATG ACCTTATCTC TAAGCAAGGC 1080GTGTTGAAAG CCAATCTCAA GAACGCAAGA TTCCTCAAAA ATGCATTCAG CGATTTCCTC 1140TATTCCATTT CTCGTTTTGA TATTACTAAA GAAATTTATC ACGATGCCAA TCTAGTAAGC 1200CAAATCAACC AGCAACGCCT GCTCTCTGAT TTGAGTTTAA AAAGCCCCAA AACCCAATTG 1260AAAATCCATA ACGGCTTGTT GGATTTAAAC ACCAAGCAAA TGGACATACT CATGGATGCG 1320GAAATCTTAA AATTCATCTT TAAAATGAAA CTTCAAGGCA GCATGCACCA GCCAAAATTT 1380TCCCTCATTT TAAACGAAAA AGCCATTCAG CAAAACCTGC AACAAGGCTT GAAAGAAATC 1440CTTAAAAACG ACACCCTTAA AAAAGGTTTA GATCATTTGC TTAAAGATGA TAAACTCAAA 1500GAAAAGCTTG AAAAAGGGCT TAAGGGGCTT TTTTAA 1536(2) SEQ ID NO 264 information

Sequence properties:

(A) length: 483 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...483

(xi) sequence representation: SEQ ID NO 264: ATGTTTGGCA TGGGCTTTTT TGAAATCCTT GTGGTGTTGA TTGTAGCGAT TATTTTTTTA 60GGACCAGAAA AATTCCCTCA AGCTGTCGTG GATATAGTGA AATTTTTTCG CGCGGTTAAA 120AAAACGCTCA ATGACGCTAA GGACACTTTA GATAAAGAAA TCAATATTGA AGAAATCAAA 180AAAGAAACCT TAGAGTATCA AAAACTCTTT GAAAACAAAG TGGAGAGTCT TAAAGGCGTT 240AAGATTGAAG AATTAGAAGA CGCTAAAGTA ACTGCAGAAA ATGAGATTAA AAGCATTCAG 300GATTTGATGC AAGATTATAA ACGCAGCTTA GAAACCAACA CGATTCCTAA CCATTTAAAT 360GAAGAAGTTT CCAATGAAGA AGCTTTAAAT AAAGAAGTTT CAAGCGATGA ATCTCCTAAA 420GAAGTCCAAT TAACAACCGA TAACAACGCC AAAGAACACG ACAAAGAAAA AGAGCATGTT 480TGA 483(2) SEQ ID NO 265 information

Sequence properties:

(A) length: 243 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...243

(xi) sequence representation: SEQ ID NO 265: ATGTTAAGAATTTTAATCCC CTTACTCATT ATTGTGTGGG TTTTATGGCG TTTGTTTTTG 60AGGCAAAAAC CCCACAAAGA TGACCACAGA GACAACCACT CTTACACGCA ACAAACCCCC 120AAAGAATTAG AAGATCACAT GATTGTATGC TCTAAATGCC AAACTTATGT CTCTAGTAAA 180GACGCCATTT ATAGTGGGGC GGTAGCCTAT TGCAGTGAAA CTTGTTTGAA GGATAAGGGG 240TAA 243(2) SEQ ID NO 266 information

Sequence properties:

(A) length: 645 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...645

(xi) sequence representation: SEQ ID NO 266: TTGGATGGTT TGAAAAAAGA AAGACAAGGA TTTTACAAGC AAGTGCATTA TTTAAGAATT 60TTAATACTGA GTATGAGTTT TTTAAATATT TTAAATGCTG AAAATTTGAG TTACATGTCT 120TCTTCTTATC AAATAGGCAC GGTGTTTATG CGCCCCTTAA ACACCAACAA ACTTTTACAA 180GGGGCTTCAA TCCTTCAAGG CTATGAAGTG AATCCTAAAA ACGACTGGGC TTATTCTAGG 240TATTATTTCT TTATAGATTA TGGTAATGTG CTTTTCAATA ACGATTCCAC TTTGCAAGCG 300AACATGTTCA CTTATGGGGT GGGAGGAGAT TTTATGGTCG CTTACGCTAA AAACCCTATC 360AACCGCTGGG CTTTTTTCTT TGGTTTGCAA CTAGCGGCTA ACACATGGAT ACTCAATAAT 420AAAGTCAAAG ATTTGGTGGT GAATACTTGG GATTCATTGA AAGATTTCAA TTTTCATAAC 480ACTTATTTTA GGGCTATCGG GAAATTTGGG GTGCAGTTTC GCACGATCGT TTTGTATCAT 540AAGGTGGATG TGGAAATTGG CATGAAAATC TTTTTAACGC CTGAAAGGCG CAGCTTGTTT 600GAAAGGAGTT TTTTGTTTTT TGTTTCGCAC TCGTGGCATT TTTAA 645(2) information SEQ ID NO 267

Sequence properties:

(A) length: 336 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...336

(xi) sequence representation: SEQ ID NO 267: ATGAAACCAA CGAACGAACC TAAAAAACCT TTTTTTCAAA GTCCCATTGT TCTTGCGGTT 60CTTGGAGGGA TTTTACTCAT TTTTTTCCTA CGCTCTTTCA ATTCTGATGG CAGTTTTTCG 120GACAATTTCT TAGCTTCTAG CACTAAAAAT GTGAGCTACC ATGAAATCAT ACAGCTCATC 180AGCAATCATG AAGTGGGAAA TGTGAGTATC GGTCAAACTT TGATCAAAGC CAGCCATAAA 240GAGGGCAATA ATCGTGTGAT TTATATCGCT AAACGAGTGC TGATCTACCT TAGTGCCTTT 300GTTAGACGAG AAAAAAATCA ATTATTCTGG TTTTGA 336(2) SEQ ID NO 268 information

Sequence properties:

(A) length: 624 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...624

(xi) sequence representation: SEQ ID NO 268: ATGTTAAGGG TTTTAAGCGT TGGTGTTGTT TTTATTTTAC TAGGGTGTCA GTTTTTCAAC 60AAAACGACTC TGCATTTAAA ATATAAGGAT TACCCCAAAA ACAGCCCTTT AAAAACCGCT 120TCCACTTTAA CCCCCCCTAA AATCTTTTTT AACGCTCATT TTGTGCCGCC CTTTTACCAA 180AAAGAATTTA AAAAAGCGCT CGCCCAGCAA ATCGCTTATT TTTTAAAGGA TAAAAGCGCT 240CTCACTTTCA ATATTTCAGG CAATGTTTTT TTTTCTTTTG AAGAGAGTCC TAAGGATTTA 300AAAGCCATTA AAGAAAGGCT TAAAAAGACG ATTGAGCCTA ACACTGACCC AAAAGCCGTC 360ATGCGTTTTT TAAACCTTCA AGCGAGCTTG ATTTTAGAAT GTGTCCCACA AACCGCTTGC 420CCATTTGACA CCCTTTTAAT CCCCACCGCT CTCAGCGTGC CTATTGATTA CGCCAATCGT 480TTGGGCGATA ACCCCTCTCT TTTTCCCCAA GAAGATAAAT CCTATCATAA CGCTTTAATC 540AAAGCCCTTA ATAAGGCTTA CTATTCTCTT ATGGAGGGTT TAGAAAAGCG TTTGAACGCT 600ATAGAAAATG CGGCATGGCT TTAG 624(2) SEQ ID NO 269 information

Sequence properties:

(A) length: 528 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...528

(xi) sequence representation: SEQ ID NO 269: ATGAAAAATC AAGTTAAAAA AATTTTAGGG ATGAGTGTGG TAGCAGCGAT GGTGATCGTA 60GGTTGTAGCC ATGCCCCAAA ATCAGGTATC AGTAAAAGCA ATAAGGCATA CAAAGAAGCG 120ACTAAAGGCG CTCCTGATTG GGTTGTAGGG GATTTGGAAA AAGTGGCGAA GTATGAAAAA 180TATTCAGGGG TCTTTTTAGG AAGGGCTGAA GATTTGATCA CTAATAATGA TGTGGATTAT 240TCTACGAATC AGGCTACAGC CAAAGCTAGG GCTAATTTAG CGGCGAATCT AAAGTCCACT 300TTACAAAAAG ATTTGGAAAA TGAAAAAACC AGAACGGTAG ATGCTTCTGG TAAAAGGTCC 360ATAAGCGGCA CTGATACTGA AAAAATTTCT CAATTAGTGG ATAAGGAATT GATCGCTTCT 420AAAATGCTTG CCCGCTATGT CGGTAAAGAT AGGGTTTTTG TTTTAGTGGG CTTGGATAAG 480CAAATTGTGG ATAAAGTGCG CGAAGAGTTA GGCATGGTTA AAAAGTAG 528(2) SEQ ID NO 270 information

Sequence properties:

(A) length: 267 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...267

(xi) sequence representation: SEQ ID NO 270: ATGAAAAAAA TCGTTGTGAG TTTATGCGTG GCGTTAGGTT TTTTAAGCGC GGATCCAGCG 60CAGGCCAATA AAGCGATCAG TGATGCGGAT TTGATTGAAG AGATAAGGGA CTTGAAAAAA 120ATCATCAGCG CACAAAACAC GGAGATTAAC CAATTAAGAA AAGTGCAAGA AGTCTTATCT 180GGGCAATTAG GGGACATGCG TAAGGATATA TTAAGCACTA GAGATTACTG TATCAGCTTA 240AGGCCTTATA TTTATAATTG GCGCTAG 267(2) SEQ ID NO 271 information

Sequence properties:

(A) length: 774 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...774

(xi) sequence representation: SEQ ID NO 271: TTGAATAGCG GCTCTAACGC TTCATTGTAT GGCACAAGCG CCGGCGTAGA CGCTTTCCTT 60AACGGGAATG TGGAAGCCAT TGTGGGCGGT TTTGGAAGCT ATGGTTATAG CTCCTTTAGC 120AATCAAGCGA ACTCTCTTAA CTCTGGGGCC AATAACGCTA ATTTTGGCGT GTATAGCCGT 180TTTTTTGCCA ACCAGCATGA ATTTGACTTT GAAGCTCAAG GGGCGCTAGG GAGCGATCAA 240TCAAGCTTGA ATTTCAAAAG CACTCTATTA CAAGATTTGA ATCAAAGCTA TAATTACTTA 300GCCTATAGCG CCACAGCAAG AGCGAGTTAT GGTTATGACT TCGCGTTTTT TAGGAACGCT 360TTAGTGTTAA AACCAAGCGT GGGCGTGAGC TATAACCATT TAGGTTCAAC CAACTTTAAA 420AGCAATAGCC AATCACAAGT GGCTTTAAAA AATGGCGCGA GCAGTCAGCA TTTATTCAAC 480GCTAACGCTA ACGTGGAAGC GCGTTATTAT TATGGGGACA CTTCATACTT TTATTTGCAT 540GCGGGAGTTT TACAAGAGTT CGCTCACTTT GGATCGAATG ATGTGGCGTC TTTAAACACC 600TTTAAAATCA ATGCCGCTCG CAGTCCTTTA AGCACCTATG CAAGAGCGAT GATGGGTGGG 660GAATTGCAAT TGGCTAAAGA AGTGTTTTTG AATTTGGGCG TGGTTTATTT GCACAATTTG 720ATTTCCAACG CAAGCCATTT CGCTTCCAAT TTAGGAATGA GGTATAGTTT CTAA 774(2) SEQ ID NO 272 information

Sequence properties:

(A) length: 852 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...852

(xi) sequence representation: SEQ ID NO 272: ATGTTTGAAG ATTTTTATCG CACTACCCTC TCTTTTTTAA GGTCTTTATT GCTTTTATTG 60GGTTTATTGT TGCCGTTTTC GCTTTGTATA GCTGATGAAT ATATTAGCAT AAGTGATGAT 120TGGGATGAAA GGGCGCGAAA TCAGTGGGAT GAAACTGCGC GAAATCATAA GACATATTAT 180TTTGAAAATG GTTTAGACCA TTTTAATCAA GGCCAATACA AGCAAGCCTT TAAAGATTTT 240AAATTGGCGC AAGAATACAG CATCGGGCTT GGCAACGTTT ATTTAGCCAA AATGTATTTG 300GAGGGAAAGG GCGTGAAAGT GGATTACAAA AAAGCGCAAT TCTATGCACA AAACGCTATC 360AAAGGGTATG GGAGCGGGTT GTTAGGGGGC GCTCTTATTT TAGGACGCAT GCAAGCAGAA 420GGCTTAGGGA TGAAAAAGGA TTTGAAACAA GCACTCAAGA CTTACAGGCA TGTGGTTCGC 480ATGTTTTCTA ATAAAAGTGC AAATTTTGCT AACAAATTTG GATCAAACCT TGCGGAATTT 540ACTAGTATGC TTATTGGATC GCGATTCATT GATCTTTCAG GTTTGAGCGC GAATCCTATA 600AAATTTGGAA ATAAATTTGG AATACTTGTT AAGAAAGCCC TTCAAATCAA AGATAATACA 660CTTTCTTGGG AAGACATTGC TGAAATTTCA AGCAATATTA TTTTACTCAA ACAACAAATG 720GGGGAAATCC TTTATAGGAT TGGGATCGCT TATAAAGAAG GGCTTGGCAC TAGAAAGAAA 780AAGGACAGGG CTAAAAAATT CTTGCAAAAA TCCGCAGAAT TTGGCTATGA AAAAGCCATG 840GAAGCTCTGT AG 852(2) SEQ ID NO 273 information

Sequence properties:

(A) length: 2361 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2361

(xi) sequence representation: SEQ ID NO 273: TTGTGCAAAA TTCCACTTTC TCTAACGCTA ATGGAGGCAC GCTCAGTTTT AACGCAGGAA 60ATTCGCTCAT TTTTGCCGGA AACAACCACA TCGCTTTCAC TAACCATTCT GGAACGCTCA 120ATTTGTTGTC TAATCAAGTT TCTAACATTA ACGTCACCAT GCTTAACGCA GCAACGGCCT 180AAGATTAACG CCACTAATAA CAATGTTTCC GTGTCTCAAG GCAATCTGTT TATCAACGCT 240AGCTGCGTGC AACAAAGCGA TCCAACGACA GCTAGCGCCA CAAACCCTTG CACCACCGCT 300CAAAATAACG CTTCTTCTAG TAATGCGTCA AACAACGCGC CAATCGCCTT AAATAATAAC 360GATGAAAGCT TGGTGGTTAC GGCGAATGGT TTCAATTTTT CAGGCAATAT TTACGCTAAC 420GGGGTGGTTG ATTTTTCAAA AATTAAAGGC TCTGCAAACG TTAAAAACCT GTATCTTTAC 480AATAACGCTC AATTCCAAGC CAACAACCTC ACGATTTCCA ACCAAGCGGT ATTAGAGAAA 540AACGCTAGCT TTGTAACGAA TAACTTAAAC ATTCAAGGAG CGTTTAACAA CAACGCCACG 600CAAAAAATAG AGGTGCTTCA AAATTTAGTG ATCGCTTCAA ACGCTTCTTT AAGCACCGGG 660ATTTATGGGT TAGAAGTAGG GGGGGCATTG AATAATTTGG GAGCGATCCA TTTTAATTTA 720GAAAATTCTC AAACGCCTGT AAATCCGCTC ATTCAAGTAG GGGGGATCAT TAATCTCAAC 780ACCACCCAAA CGCCTTTTAT GAATGTCAGC GTGGCTAATG GCGGAACTTA CACTTTATTA 840AAAAGCAGCC GTTATATTGA TTACAATATC AACCCTAACA GCTTGCAATC GTATTTGAAG 900CTCTATACCT TAATCAATAT CAACGGAAAC CACATAGAGG AAAAAAACGG CGTATTGACT 960TATTTGGGCC AACGGGTTTT ATTACAAGAT AAGGGGTTAT TATTGAGTGT AGCACTACCT 1020AACTCAAACA ACGCCTCTCA AAACAACATT TTAAGCCTTT CTGTCCTTCA CAACCAGATT 1080AAAATGTCTT ATGGTAATAA AGTGATGGAC TTTACCCCTC CCACCTTACA GGATTACATT 1140GTGGGCATTC AAGGACAAAG CGCACTCAAT CAAATTGAAG CTGTTGGGGG GAATAACGCT 1200ATCAAGTGGC TTTCAACATT GATGATGGAG ACTAAAGAAA ACCCGCTTTT TGCGCCGATT 1260TATTTAGAAA ACCACTCTTT AAATGAAATC TTAGGCGTAA CAAAAGATCT TCAAAACACC 1320GCAAGCTTGA TTTCTAACCC TAATTTTAGA AATAACGCTA CCAGCCTTTT AGAAATGGCG 1380AGTTACACCC AACAAACCAG CCGTTTGACA AAACTCTCTG ATTTTAGGGC TAGAGAGGGA 1440GAGTCCAATT TTTCAGAGCG CTTGTTAGAG CTTAAAAACA AGCGTTTTAG CGATCCTAAC 1500CCTAGTGAGG TTTTTGTCAA ATACTCTCAA CTCAGCAAAC ACCCCAATAA CCTTTGGATT 1560CAAGGGGTGG GAGGAGCGAG CTTTATTTCT GGGGGCAATG GCACGCTTTA TGGCTTGAAT 1620GTGGGCTATG ACCGATTGGT TAAAAGCGTG ATCCTTGGGG GTTATGTGGC TTATGGCTAT 1680AGCGGTTTTA ACGGGAACAT CATGCATTCT TTGGCTAATA ATGTGGATGT GGGGATGTAT 1740GCGAGGGCTT TTTTGAAAAG AAACGAATTC ACTTTGAGCG CGAATGAAAC TTATGGAGGC 1800AATGCGAGTC ATATCAATTC TTCTAATTCC TTGCTCTCTG TGTTGAACCA ACGCTACAAC 1860TACAACACCT GGACAACGAG CGTGAATGGG AATTACGGCT ATGATTTCAT GTTCAAACAA 1920AAAAGCGTGG TGCTAAAACC TCAAGTGGGC TTGAGCTATC ATTTCATAGG CTTGAGCGGG 1980ATGAAAGGTA AAATGCAAAA TCCAGCTTAC CAACAATTCG TCATGCATTC AAACCCTTCT 2040AACGAATCGG TTTTAACGCT CAACATGGGG TTAGAGAGCC GTAAATATTT TGGTAAAAAT 2100TCCTATTATT TTGTAACGGC GAGGTTGGGT AGGGATCTTT TGATCAAAGC TAAAGGCGAC 2160AATGTGGTGC GTTTTGTGGG TGAAAACACT TTATTGTACC GCAAGGGGGA AATTTTTAAC 2220ACTTTTGCGA GCGTGATCAC AGGAGGCGAA ATGCATTTGT GGCGTTTGAT GTATGTGAAT 2280GCGGGGGTGG GGCTTAAAAT GGGCTTGCAA TACCAAGATC TTAATATCAC TGGGAATGTG 2340GGCATGCGAG TGGCGTTTTA G2361 (2) SEQ ID NO:274 information

Sequence properties:

(A) length: 1446 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1446

(xi) sequence representation: SEQ ID NO 274: ATGTTTAGAA AACTAGCAAC CTCTGTATCG CTCATAAGCC TACTAATCTC CAACGCTCTT 60TATGCTAAAG AAATAAGTGA AGCCGATAAG GTCATTAAGG CCACTAAAGA AACTAAAGAG 120ACCAAGAAAG AGGCTAAACG CCTCAAAAAA GAAGCTAAAC AGCGCCAACA GATCCCTGAT 180AATAAGAAAC CTCAATATGT CTCTGTTGAT GACACAAAAA CTCAAGCGCT TTTTGATATA 240TATGACACTT TGAATGTGAA TGACAAAAGC TTTGGGGATT GGTTTGGTAA TAGCGCTTTG 300AAAAACAAAA CTTATCTCTA CGCTATGGAT CTATTGGATT ATAACAACTA CTTATCCATA 360GAAAACCCTA TTATCAAAAC AAGAGCGATG GGAACTTATG CAGATCTGAT TATCATCACA 420GGTTCGTTAG AACAAGTCAA TGGGTATTAC AATATTCTAA AAGCGCTCAA CAAACGCAAC 480GCTAAGTTTG TGTTAAAAAT CAATGACAAA ATACCTTATG CCCAAGCGAC TTTTTTGAGA 540GTGCCAAAAA GAAGCGATCC CAACGCCCAC ACGCTTGATA AGGGAGCGTC AATTGATGAA 600AGCAAGCTTT TTGAACAACA AAAGAAAATG TATTTCAACT ACGCCAACGA TGTGATCTGC 660AGACCCAACG ATGAAGTGTG TTCGCCCCTA AGAGATGAAA TGGTAGCTAT GCCCACTAAC 720GATAGCGTTA CTCAAAAACC CAATATCATT GCTCCTTATA GCCTGTATAG ACTAAAAGAG 780ACAAATAACG CCAATGAAGC CCAACCATCA CCTTATGCCA CTCAAACCGC TCCTGAAAAC 840AGCAAAGAGA AGCTCATAGA AGAGCTAATC GCCAACTCCC AACTCATAGC CAATGAAGAA 900GAGAGGGAAA AGAAACTCTT AGCAGAAAAA GAAAAACAAG AGACTGAATT GGCTAAATAC 960AAGCTCAAAG ATTTAGAAAA TCAAAAGAAA CTAAAAGCTT TAGAAGCAGA GTTGAAAAAG 1020AAAAACACTA AGAAACCTAG AGTAGTGGAA GTGCCTATTC CTCCTAAAAC AAGTGATTCT 1080GATGAAACAA TGAGAGTTAT CAAAGAAAAA GAAAACTATA ATGGGTTATT AGTGGATAAA 1140GAGACCACGA TCAAAAGAAG CTATAAGGGG ACTTTGATCA GTGAAAATTC TTACAGCAAA 1200AAAACACCCA TCAACCTTGA GGACTTGAGA AGCTTAGAAG AAGAAATTAA GAGCTACTAT 1260GTCAAGTCTA ATGGCTTGTG TTACGCTAAT GGCATTAACC TCTATGTAAA AATCAAAAAC 1320GATCCCTACA AAGAGGGAAT GCTGTGTGGT TATGAGAGCG TTCAAAAACT GCTTTCACCA 1380CTAAGGGACA AGCTCAAATA CGACAAGCAG AAGTTACAAA AAGCGTTACT GAAAGATTTA 1440AAGTAA 1446(2) SEQ ID NO 275 information

Sequence properties:

(A) length: 180 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...180

(xi) sequence representation: SEQ ID NO 275: TTGCTTTCCC GGTCTATGCC CAAAATTCAC GCCGTTTTCA AAGCTTTTAT CCCTATTCCA 60TTCGCCCTCT TCGCTATCCA CTTCGTAGTA TTGGGAATTG GAAGCGTCTT TAATCTTAAT 120AGAATCAAAG ATAAAAAATT CATTCTCCGC GCCAAAATAA GCCACATCGC CCAAGCCTAA 180(2) SEQ ID NO 276 information

Sequence properties:

(A) length: 792 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...792

(xi) sequence representation: SEQ ID NO 276: ATGAGAAAAA CGATTTCAGC GTTGTTTTTA TCAGCGTGTA TAGGGTTATC GTCTGTTCAT 60GCGAGTAACG CTTTGATTTT ACAAACAGAT TTTAGCCTAA AAGATGGGGC CGTCTCGGCG 120ATGAAAGGCG TCGCTTTCAG CGTTGATTCT AATCTTAAAA TCTTTGATTT AACGCACGAA 180ATCCCCCCGT ATAACATTTG GGAAGGCGCT TACCGCTTGT ATCAGACCGC TAGTTATTGG 240CCAAAAGGCT CGGTATTTGT GAGCGTAGTG GATCCGGGCG TAGGCACTAA TCGTAAATCG 300GTGGTATTGA AAACTAAAAA CGGCCAGTAT TTCGTCTCTC CAGATAACGG CACGCTGACT 360TTGGTAGCGC AAACTTTGGG GATTGATAGC GTGCGTGAAA TTGATGAAAA AGCCAACCGC 420TTGAAAGGTT CTGAAAAATC CTATACTTTC CATGGCCGTG ATGTGTATGC TTACACTGGG 480GCGCGCTTGG CTTCTGGGGC GATCACATTC GAGCAGGTCG GGCCAGAGCT TCCTATAAAA 540GTTGTTGAAA TTCCTTACCA AAAAGCGAAA GCCACAAAAG GGGGAGTGAA AGGCAATATC 600CCGATTTTGG ATATTCAATA TGGCAATGTT TGGAGCAATA TCAGCGATAA ACTGCTCAAT 660CAAGCAGGGA TCAAACGAAA CGATACAGTG TGTGTAACTA TTTTAAAAAT TCCAAGAAAC 720AATACGAAGG GAAAATGCCG TATGTCGCGA GCTTTGGCGA TGTGCCAGAA GGCCAGCCGT 780TGGTCTATTT AA 792(2) SEQ ID NO 277 information

Sequence properties:

(A) length: 345 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...345

(xi) sequence representation: SEQ ID NO 277: ATGAATATCA AAACCCATTC TTCAAATGAA AAAGAACGCT TTGTACGCAT AGAAGAGGAC 60GAAAAGAAAG AATTATTCGC CGAAGCTACA AATGAAAATC CGCACGGCCT TTCTTTAATG 120GCTTTAATAG GGGTGTTGGT TTTTGGGGGT GCGTTTTTAG CCTTATTAGT GCCTAAAATC 180TATTTAAGCA ATAATATCTA TTATATTAGC CGTAAAATTA ATACCCTAGA AGATCAAAAA 240CGCCTGCTTT TAGAAGAACA GCAAATCCTA AAAAACGAAT TAGAAAAAGA GCGTTTTAAA 300TACTACATAG AGAATAGTGA AAATATTGGC GATATTGCGT TTTAA 345(2) SEQ ID NO 278 information

Sequence properties:

(A) length: 2826 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2826

(xi) sequence representation: SEQ ID NO 278: TTGCAACATA AAACCATTAT GGATAAGATC ATTATTCAAG GGGCTAGGGA AAACAATCTC 60AAAAATATCT TTTTAGAAAT CCCTAAAAAC CAATTTGTTG TTTTTACCGG ATTAAGCGGT 120TCGGGTAAAT CCACTCTGGC GTTTGACACT CTATACGCTG AAGGGCAAAG GCGCTATTTA 180GAGAGTTTGT CTAGTTATGC GAGGCAATTT TTAGACAAAG TGGGTAAGCC TAATGTGGAT 240AAAATTGAAG GCCTAACCCC AGCGATCGCT ATTGATCAAA AAACCACTTC TAAAAACCCT 300AGATCCACTG TGGGGACGAT CACTGAGATT TATGATTATT TAAGGTTGTT GTTTGCAAGG 360GTTGGGGAGC AATTTTGCCC CACATGTTTA GAGCCTATTA GTTCTATGAG CGCGAGCGAT 420ATCATTTCTC AAATCTGTCA TTTAGAAGAA AATTCTAAAA TCATTATTCT AGCCCCCATT 480ATTAAAGATA AAAAAGGTTC GTTTAACGAT AAATTAGAGA GTTTGCGTTT GAAGGGGTAT 540GTGAGGGCTT TTGTTGATGG GGTGATGGTG CGTTTAGATG AAGAAATCCA TTTGCACAAA 600ACCAAAAAAC ACACCATTGA AGCGGTGGTG GATAGGGTGG TTATCAATAG CGAAAATGCT 660TCACGGATCG CTAGCGCGGT AGAAAAAGCC CTTAAAGAAA GCTATGGGGA ATTAGAAGTG 720GAAATCTTGC AAGACAACGC ACCAAGTATT AGGAAGCATT ACAGCGAGCA TAAGGCATGT 780TTTAAGTGCA AGATGAGTTT TGAAGAATTA GAGCCTTTGA GTTTTTCCTT CAATTCGCCT 840AAAGGGGCGT GCGAAAGTTG TTTGGGTTTA GGGACAAAAT TTAGCTTAGA TATTAGTAAG 900ATTTTAGATC CTAACACGCC TTTAAATCAA GGAGCGATTA AAGTGATTTT TGGGTATAAC 960CGCAGTTATT ACGCTCAAAT GTTTGAAGGC TTTTGCACTT ATAATGGCAT TGACAGCGCG 1020CTTTGTTTCA ACGAATTGAA CAAAGAGCAG CAAGACGCTC TTTTGTATGG GAATGGCACT 1080GAAATCAGCT TTCATTTTAA AAACAGCCCC TTGAAACGCC CCTGGAAAGG CATTATCCAA 1140ATCGCTTATGACATGTTTAA AGAGCAAAAG GATTTGAGCG ATTACATGAG CGAAAAAACC 1200TGTTCTTCGT GTAATGGGCA TCGCTTGAAA GCCTCAAGTT TGAGCGTCCA AGTCGCTGGC 1260TTGAAAATGG CGGATTTTTT AACTAAGCCC ATTGAAGAAG TCTATCATTT TTTTAATGAT 1320CCCACGCATT TTAACTATCT TAACGAGCAA GAAAAAAAGA TCGCTGAACC CATTTTAAAA 1380GAGATTTTAG AAAGGGTGTT TTTTTTATAC GATGTGGGGC TAGGGTATTT GACTTTGGGG 1440AGGGATGCGC GAACGATTAG CGGAGGGGAG AGCCAAAGGA TACGAATCGC CAGTCAAATC 1500GGGAGCGGTT TGACAGGGGT TTTGTATGTT TTAGACGAGC CTAGCATTGG CTTGCATGAA 1560AAAGACACGC TCAAACTCAT CAACACCCTT AGGAATTTAC AAAAAAAGGG GAACACGCTC 1620ATTGTCGTAG AGCATGATAA AGAGACGATT AAGCATGCGG ATTTTGTTGT GGATATTGGG 1680CCAAAGGCTG GAAGGCATGG GGGTGAAGTG GTTTTTAGCG GGAGCGTAAA AGATTTATTG 1740CAAAATAACC ATTCTACCGC CTTGTATCTC AACGGCACTA AAAAGATTGA GCGCCCCAAA 1800TTTGAACCCC CTAAAGAAAA GCATTTTTTA GAAATTAAAA ATGTCAATAT CAATAACATT 1860AAGAATTTGA GCGTTCAAAT CCCCTTAAAA CAATTGGTGT GCATTACGGG GGTGAGCGGG 1920AGCGGTAAAA GCTCGCTGAT TTTACAAACC CTTTTACCCA CCGCTCAAAC CCTTTTAAAC 1980CATGCTAAAA AAAATCAAAG CTTGAATGGG GTGGAGATTG TAGGGTTGGA GTATTTGGAT 2040AAAGTGATTT ATTTAGATCA AGCCCCCATA GGCAAAACCC CACGAAGCAA CCCCGCCACT 2100TACACGGGAG TGATGGATGA AATCAGGATT TTATTTGCCG AGCAAAAAGA AGCTAAAATT 2160TTAGGCTATA GCACGAGCCG TTTCAGCTTT AATGTTAAAG GAGGGCGGTG TGAGAAATGC 2220CAAGGCGATG GGGATATTAA AATAGAAATG CACTTTTTGC CTGATGTGTT AGTCCAATGC 2280GATAGCTGTA AGGGCGCTAA ATACAACCCC CAAACTTTAG AAATCAAGGT GAAAGGCAAA 2340TCCATTGCTG ATGTGTTGAA CATGAGCGTG GAAGAAGCTT ATGAATTTTT TGCTAAATTC 00 2400CCTAAAATCG CTGTGAAGTT AAAAACGCTT ATAGATGTGG GCTTAGGCTA TATCACTTTA 2460 2520TTGAGTAAAA AAGACACAGG CAAAACCCTT TATATTTTAG ATGAGCCTAC CACCGGTTTG 2580CATTTTGAAG ATGTGAATCA CCTTTTACAA GTCTTGCATT CTTTGGTGGC GTTAGGCAAT 2640TCCATGCTAG TGATTGAGCA TAATTTAGAC ATCATCAAAA ACGCTGACTA CATTATAGAC 2700ATGGGGCCTG ATGGGGGGGA TAAGGGCGGG AAAGTCATTG CGAGCGGCAC GCCTTTAGAA 2760GTGGCGCAAA ATTGCGAAAA AACCCAAAGC TATACGGGAA AATTTTTAGC TTTGGAATTG 2820AAATAG 2826(2) SEQ ID NO 279 information

Sequence properties:

(A) length: 252 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...252

(xi) sequence representation: SEQ ID NO. 279: ATGAATTACG ATGTTTTAAT GGGATTTTTA GCACTAATCT TGCTAATTCT TTGGTATGCC 60TATGGATTAA GGCAATATCT TAAATTAAAA GATAAGAATA AGAGATTAAA AGAGAAATTA 120CAACGCTGTA ATTGTAATAT TAAAATTCCT AGTATTCTTG AAATGGCGCA TAAACCTATC 180ATTATGGATA TTAAGGGGGA ATTGCTACCA CATCTTACAG AGAGTTATAG AAAATCAAAA 240TTTAAGGAGT AA 252(2) SEQ ID NO. 280 information

Sequence properties:

(A) length: 840 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...840

(xi) sequence representation: SEQ ID NO 280: ATGAGAGTAA TAATAAAGTT TATGCTGATT TCATTAAAAA CATTCCTAAA AATATTATTG 60AAAATATTCC TAAAAACCTT CCAAAAGATT TGGATAGTTT GCGTGGTTAT TTGGGGGTTG 120GGCTGTAGTT TTTTAAACGC TAACAGCGTT CAATTAGAAG AAACGCTGAG ACGAAATCCT 180AAAAATCTTA TTTGGCAACA CTTTAAAAAG AAGTTTAAAA AGAGTAACAC GATCCCTTAT 240GCCCCTAATA GCCGTTGGAA ATATTTAGGC ACAAGTATAG GGATTTTGGG CGTGTCGTTG 300GTGATAGGGA TTGTGGGGTT GTATCTCATG CCAGAGAGCG TAACGAATTG GGATAAAGAA 360AAGTTTGGCG TCAAAAGTTG GTTTGAAAAT GTCCGCATGG GGCCAAAACT AGACAATGAT 420AGTTTTATTT TTAATGAAAT CTTGCACCCT TATTTTGGGG CTATGTATTA CATGCAACCG 480CGCATGGCTG GGTTTAGCTG GATGACATCA GCGTTTTTTT CTTTTATCAC TTCTACGCTT 540TTTTGGGAAT ATGGCTTGGA AGCGTTTGTG GAAGTGCCTA GCTGGCAGGA TTTGGTGATC 600ACGCCCTTAC TAGGTTCCAT TTTAGGGGAA GGGTTTTACC AGCTCACGCG CTATATCCAA 660CGCAACGAAG GCAAGCTGTT TGGCTCTTTA TTTTTAGGGC GTTTAGCCAT CGCCCTTATG 720GATCCTATCG GTTTTATCAT TAGGGATTTA GGGCTTGGGG AAGCCTTAGG GATTTATAAT 780AAACATGAAA TCCGTTCTAA TTTAAGCCCC AATGGTTTGA ATTTGACTTA CAAATTTTAA 840(2) SEQ ID NO 281 information

Sequence properties:

(A) length: 531 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...531

(xi) sequence representation: SEQ ID NO 281: ATGAAACTTT TTAACCCTCG TTTAATCGTT TTTATATTCG CGCTTCTTTT AGGGGTAGGG 60TTTTCTGTGC CTTCTTTGCT AGAAACTAAA GGCCCTAAAA TCACTTTAGG TTTGGATTTA 120AGGGGGGGGT TGAACATGCT TTTAGGGGTG CAAACCGATG AGGCTTTAAA AAACAAGTAT 180TTAAGCCTAG CGTCTGCTTT AGAATACAAC GCTAAAAAGC AAAATATCTT GCTTAAAGAC 240ATTAAATCCA GTTTAGAGGG GATCAGTTTT GAGCTTTTAG ATGAAGATGA GGCGAAAAAA 300TTAGACGCGC TTTTATTGGA ATTGCAAGGT CATAGCCAGT TTGAAATCAA AAAAGAAGCG 360GAGTTTTATA GCGTGAAACT CACCCCTTTA GAGCAAGAGG AATTGCGTAA AAACACGATC 420TTGCAAGTGA TAGGGATCAT TCGTAACCGC TTGGATCGAT TTGGCTTGGC AGAGCCTGTA 480GTCATTCAGC AAGGCCGAGT AGAATTTCGG TGCAATTGCC CGGCATTAAG A531 (2) information SEQ ID NO 282

Sequence properties:

(A) length: 840 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1311

(xi) sequence representation: 282: ATGATGAAAT TTTTTCTTTT AAAGAAATTC AGCGAATTTT TAAACACTCA AACGCATTTT 60AACCTCAAAC GCTTGAACGC GTCTAGTTTT TTATTAGAGA CTTTTTCTAA AGAAAAACAC 120GCCTTTGTTG TGGATTTGAG CGCGCCTTAT ATTGGTTTGT CCAAAAAACC CCCAGAGAGC 180GTTTTAAAAA ACACTTTAGC GTTAGATTTT TGTTTGAATA AATTCACCAA AAACGCCAAA 240ATTTTACAAG CAAACGTCAT TGATAACGAT CGGATTTTAG AAATCAAGGG CGCTAAAGAT 300TTAGCTTATA AGAGTGAAAC TTTTATTTTG CGTTTAGAAA TGATCCCTAA AAAAGCCAAT 360CTCATGATTT TAGATCAAGA AAAATGCGTG ATAGAGGCTT TTCGTTTTAA TGACAGGGTG 420GCTAAAAACG ATATTTTAGG GGCATTGCCT CCTAATATTT ACGAGCATCA AGAAGAGGAT 480TTGGATTTTA AGGGATTGTT GGACATTTTA GAAAAAGATT TTTTATCCTA TCAGCACAAA 540GAATTGGAAC ACAAAAAAAA TCAAATCATC AAGCGATTAA ACGCCCAAAA AGAACGCTTG 600AAAGAAAAAT TAGAAAAACT AGAAGATCCT AAAACTTTAC AGCTGGAAGC GAAAGAATTG 660CAAACTCAAG CCTCATTGTT GCTCACTTAC CAGCATTTAA TCAACAGGCG TGAAAATCGC 720GTGATTTTAA AGGATTTTGA AGATAAAGAA TGCATGATTG AAATTGATAA GAGCATGCCC 780TTAAACGCTT TTATCAATAA AAAATTCACT CTCAGCAAGA AAAAGAAACA AAAATCGCAA 840TTCTTGTATT TAGAAGAAGA GAATCTGAAA GAAAAAATCG CTTTTAAGGA AAATCAAATC 900AACTATGTTA GAGACGCTGC AGAAGAAAGC GTTTTAGAAA TGTTTATGCC GGTAAAAAAC 960TCTAAAATCA AACGCCCGAT GAACGGGTAT GAAGTGCTGT ATTATAAGGA TTTTAAAATC 1020GGTTTAGGGA AAAACCAAAA AGAGAATATC AAGCTTTTAC AAGACGCAAG AGCGAATGAT 1080TTGTGGATGC ATGTGAGAGA TATTCCTGGA TCGCATTTGA TCGTTTTTTG CCAAAAGAAT 1140ACGCCTAAAG ATGAGGTCAT TATGGAATTA GCCAAAATGT TGATTAAAAT GCAAAAAGAT 1200GCGTTTAATG GTTACGAGAT TGACTACACG CAACGAAAAT TTGTCAAAAT CATCAAAGGA 1260GCTCATGTCA TTTACTCAAA ATACCGAACT ATTAGTCTAA AGGACACTTA A1311 (2) SEQ ID NO 283 information

Sequence properties:

(A) length: 294 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...294

(xi) sequence representation: 283: ATGGGACAAA CTAAAGAAAT TATAACGACG CTTTTACCCC TTTTGGTGTT GTTTCTTATT 60TTTTATTTTT TGATCGTTCG CCCGCAACGC CAACAGCAAA AAAAGCATAA AGAAATGATA 120GAGGGCTTGA CTAAGGGCGA TAAAATTGTC ACTCAAGGAG GGCTGATCGT TGAAGTGCTT 180AAAGCGGAAG CGAATTTTTT TAGCGTGAAA CTCAATGATG ACACCACCGC TAAACTTTCT 240AAAAACTATG TAGCGTTCAA ATTAGACGAA GAAACAACAC CCAACAACAA CTAA 294(2) 284 information of SEQ ID NO

Sequence properties:

(A) length: 621 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...621

(xi) sequence representation: SEQ ID NO 284: TTGAAGTTTC AAATTGTGAG TTTGTTATTG GCTTTTTTAT TAGCCTCTTG TTTGCCCCCT 60AAGGGCCATC ATTCTGGTTT GGTGAATATG TATATTGCGC ATCAAGGCCA GAGCGTACGC 120ACTTATTGGC GCAAAGTGGA TAGAGGAGTT GTCGCCAAAC ACAATGAAAC GCTTAAAGAA 180AACCCCAAAA TAAAGCTCAA AGACCCTAAG GGGCCTTTGT TCATGCTAGG GAGCAATCGT 240TTCATGCTTT TATGGAAAAA CCGCTATACT TTAGCTAAAG TCCAATCGTT CAAGCTAGAG 300CCTGGGTTTT ATTACTTGGA TTCTTTTAGC GTGGAAACTC AAAAAGGCAT CTTGCAAAGC 360GCTCCTGGCT ATTCATACAC CAAAAATGGC TACGATTTTA AGAACAACCG CCCCTTTTTC 420CTAGCCTTTG AAGTCAAACC TGACAGCAAG ATCGTTCTCC CTAGCGTGGA ATTGAGCTTG 480ATTAAAACCC CTAGAGGCTT TTTAGGGGTG TTTTTATTTG ACAACAACGA AAAGGGGGCT 540AATACCCCAT GGATTGAGGG GAGCTTGAAT TTAAAGCTTA AAAACGCTTC TTTTAAAGAC 600GCATGGGAGT TGGAACGATA A621 (2) information SEQ ID NO 285

Sequence properties:

(A) length: 1599 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1599

(xi) sequence representation: SEQ ID NO 285: ATGAGAAAGG TTATCATAAT GAATGGTTAT TTGAGGGTAA AAACCCCGTA TTTTTTAGCG 60TCGGTCGTTT TGACTTTTTG GACTTTTAAT TCTTTTATGA GCGCGAAAGA TAAGCACCAT 120TTTTTAAAAA AAGTTACAAC CACCGAGCAA AAATTCAGTT CTAGTGCCCC AATTTCATGG 180CAAAGCGAAG AGGTGCGTAA TTCCACAAGC TCTCGCACGG TGATTTCCAA CAAAGAACTC 240AAAAAAACGG GGAATTTGAA TATTGAAAAC GCCTTGCAAA ATGTGCCAGG GATTCAAATC 300AGAGACGCTA CAGGCACGGG CGTGCTGCCT AAAATTTCGG TGCGCGGTTT TGGTGGGGGC 360GGTAACGGGC ATAGCAACAC CAACATGATT TTAGTCAATG GTATCCCCAT TTATGGCGCG 420CCGTATTCCA ATATTGAACT GGCGATTTTC CCTGTAACTT TCCAGTCAGT GGATAGGATT 480GATGTGATTA AGGGGGGAAC GAGCGTCCAA TACGGCCCTA ACACTTTTGG AGGCGTGGTG 540AATGTCATCA CTAAAGAAAT CCCCAAAGAG TGGGAAAATC AAGCGGCTGA AAGGATCACT 600TTTTGGGGGC GCTCCTCTAA TGGGAATTTT GTCGATCCCA AAGAAAAAGG CAAGCCCTTA 660GCCCAAACTT TAGGAAACCA AATGCTGTTT AACACTTATG GGCGAACGGC TGGGATGTTG 720GGTAAATATA TAGGCATTAG CGCTCAAGGC AATTGGATTA ATGGGCAAGG TTTCAGGCAA 780AATAGCCCTA CAAAGGTGCA AAACTACTTG TTGGATGCGA TTTATAAGAT CAATGCGACC 840AATACTTTTA AAGCTTATTA CCAGTATTAT CAATACAACT CTTACCATCC AGGCACTTTG 900AGCGCGCAAG ATTACGCCTA TAACCGCTTC ATCAATGAGC GCCCTGACAA TCAAGATGGA 960GGGCGAGCCA AGCGCTTTGG GATCGTGTAT CAAAACTACT TTGGCGATCC GGATAGGAAA 1020GTGGGGGGCG ATTTTAAATT CACTTATTTC ACGCATGACA TGAGTAGGGA TTTTGGGTTT 1080TCCAACCAAT ACCAAAGCGT GTATATGAGC GGTCAAAATA AGATTTTACC CTTTAAAGGC 1140AAGGGAGAAA TCAGCGCAAAAAACCCTAAT TGCGGTCTGT ATTCTTATAG CGACACGAAT 1200AGCCCTTGCT GGCAATTTTT TGACAATATC CGCCGATCCG TGGTGAATGC CTTTGAGCCA 1260AAACTCAATC TTATCGTCAA TACTGGTAAA GTCAAACAAA CTTTTAACAT GGGAATGCGC 1320TTTTTAACTG AAGATTTATA CCGCCGATCC ACCACCAGGA AAAACCCTAG CATGCCTAAT 1380AATGGGAGTG GGTTTGATGC AGGAACTTCA CTCAATAATT TCAACAATTA TACCGCTGTG 1440TATGCCAGCG ATGAAATCAA TTTCAATAAC GGCATGCTAA CGATCACGCC GGGCTTGAGA 1500TACACTTTTT TAAATTACGA AAAAAAAGAC GCTCCTCCCT TTAAGGTGGG TCAAACCCCA 1560AAAACCACGA AAGAGCGTTA TAACCAATGG AATCCGGCA 1599(2) SEQ ID NO 286 information

Sequence properties:

(A) length: 768 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...768

(xi) sequence representation: SEQ ID NO 286: ATGAAAAAGA TTTTTTTAGG TATGGCATTA GCCTTTAGTG TGTCCATGGC AGAAAAAAGC 60GGCGCGTTTT TAGGAGGGGG GTTTCAATAT TCTAATTTAG AAAACCAAAA CACCACCCGC 120ACCCCAAGCG CTAACAATAA CACCCCGATA AACACTTCAA TGTTTGGCAA CAATCAAGCG 180GCTCCAGCCC AAGAAACGCC AAGCGTGATC AACACCAATA ATTACGGGCA AATGTATGGG 240GTAGATGCGA TGGCAGGGTA TAAGTGGTTC TTTGGCAAAA CCAAACGCTT TGGCTTTAGG 300ACTTATGGAT ACTACAGCTA TAACCATGCG AATTTGAGCT TTGTAGGCAG TAAGCTTGGA 360ATCATGGATG GCGCATCTCA AGTGAATAAC TTCACTTATG GCGTGGGCTT TGATGCGCTC 420TATAACTTCT ATGAAAGCAA AGAGGGCTAT AACACAGCAG GGTTGTTCGT GGGCTTTGGA 480TTAGGAGGGG ATTCGTTTAT CGTTCAAGGA GAGAGCTACT TGAAATCTCA GATGCAAATT 540TGCAACAACA CCGCCGGCTG TTCAGCGAGC ATGAACACGA GCTACTTCCA AATGCCTGTG 600GAATTTGGTT TTAGGAGCAA TTTCTCTAAA CACAGCGGGA TTGAAGTGGG CTTTAAATTG 660CCTTTATTTA CCAACCAATT CTATAAAGAA AGGGGCGTAG ATGGATCGGT AGATGTGTTC 720TATAAAAGGA ATTTCTCTAT CTATTTTAAC TACATGATCA ACCTCTAA 768(2) SEQ ID NO 287 information

Sequence properties:

(A) length: 1002 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1002

(xi) sequence representation: SEQ ID NO 287: ATGCTAATCG CTCGCTTTAA AAAAGCTTTA ATTTCCTATT CTTTAGGGGT TCTTCTTGTT 60TCATCGTTAT TAGGCGTGGC TAACGCTTCT AATCAAGAGA TCCAAGTCAA GGATTATTTT 120GGGGAGCAAA CCATAAAGCT TCCTGTTTCT AAAATAATCT ACTTGGGCAG CTTTGCAGAA 180GTGCCTGCCA TGTTCAATAC TTGGGATAGG GTCGTGGGCA TTTCGGATTA CGCTTTTAAA 240TCTGATATTG TTAAAGCCAC TCTCAAAGAT CCTGAACGCA TTAAACCCAT GAGCAGTGAT 300CATGTGGCGG CGTTGAATGT GGAATTATTA AAAAAGCTTA GCCCTGATCT TGTGGTAACC 360TTTGTGGGTA ACCCTAAAGC GGTAGAGCAT GCGAAAAAAT TTGGGATTTC ATTCCTTTCT 420TTCCAAGAAA AAACCATTGT AGAGGTCATG GAAGATATTG ACGCTCAAGC TAAGGCCTTA 480GAAGTTGACG CTTCTAAAAA ATTGGCTAAA ATGCAAGAAA CTTTGGATTT TATCAAAGAG 540CGTTTGAAAA ATGTCAAAAA GAAAAAGGGG GTGGAGCTTT TCCATAAAGC CAATAAAATC 600AGCGGCCATC AAGCCCTTGA TTCAGATATT TTAGAAAAAG GGGGCATAGA CAATTTTGGC 660TTGAAATACG TCAAGTTTGG GCGCGCTGAC ATTAGTGTGG AAAAAATCGT TAAAGAAAAC 720CCTGAGATTA TTTTTATTTG GTGGATAAGC CCGCTTAGCC CTGAAGACGT GTTGAACAAC 780CCTAAATTTT CCACTATCAA AGCCATTAAA AACAAGCAAG TCTATAAGCT CCCCACAATG 840GATATTGGCG GACCTAGAGC CCCACTCATT AGTCTTTTTA TCGCTTTAAA AGCCCACCCT 900GAAGCGTTTA AGGGCGTGGA TATTAATGCG ATAATCAAAG ATTACTATAA AGTGGTCTTT 960GATTTGAATG ACGCGGAAGT TGAACCCTTT TTGTGGCACT GA 1002(2) SEQ ID NO 288 information

Sequence properties:

(A) length: 165 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...165

(xi) sequence representation: SEQ ID NO 288: ATGAAAAAGC AAATCTTGAC AGGTGTTTTG TTATCAGTTT TGGCAGTGAG TTCTGCATAC 60GCTCACAAAG ATAAAAAAGA CGCTAAAAAA CCTGAGTTAA GCTCTCAATT AGTGGCTCAC 120AAAGATAAAA AAGACGCCAA AAAACCTAAA AACTCAGTGG CCTAA 165(2) SEQ ID NO 289 information

Sequence properties:

(A) length: 429 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...429

(xi) sequence representation: SEQ ID NO 289: ATGTATAAAT TAGGAATATT TTTATTAGCC ACCTTACTAT CAGCTAACAC GCAAAAAGTG 60AGCGATATTG CTAAAGACAT CCAACATAAA GAAACCCTTT TGAAAAAAAC CCATGAAGAA 120AAAAACCAAC TGAACAGTCG TTTGAGTTCT TTAGGCGAAG CGATCCGCTC TAAAGAGCTT 180CAAAAGGTTG AGATTGAACG CCAAATGGTC GCCTTAAAAA AGAGTCTTGA AAAAAATCGT 240AACGAAAGTT TGGTGCAAGA AAAAGTCCTA ACCAACTACC GCAAGTCTTT AGATCATTTG 300CAAAAACAAC GATCGTTTTT ACAAAAGAGA GTGTTTGATA CGCTTTTAGA GGATTTTCTT 360TTCTCACAAG CCCTAAAGGG GCAGAATTTA GCCTCTTCTA ATGATGTGAT TTTGCTAAGT 420GGCGTTTGA 429(2) information SEQ ID NO 290

Sequence properties:

(A) length: 594 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...594

(xi) sequence representation: SEQ ID NO 290: ATGGATAAAA ACAACAATAA TAATCTCCGC TTGATTTTAG CGATCGCTCT GTCTTTCTTG 60TTTATCGCTC TTTATAGCTA TTTTTTCCAA GAACCAAACA AAACAACAAC CGAAACCACA 120AAGCAAGAAA CAACCAACAA CCACACAGCA ACAAGCCCCA CCGCGTCCAA TACCATCACC 180CAAGATTTTA GCGTTACCCA AACCATCCCT CAAGAGAGTT TGTTAAGCAC GATTTCTTTT 240GAACATGCCA AAATTGAAAT TGATTCTTTA GGGCGCATCA AACAGGTTTA TCTCAAAGAT 300AAAAAGTATC TAACCCCTAA AGAAAAGGGC TTTTTAGAGC ATGTGAGCCA TCTTTTTAGC 360TCCAAAGAAA ACTCGCAACC CTCCCTAAAA GAGCTCCCCC TTTTAGCAGC CGATAAACTC 420AAGCCTTTAG AAGTGCGTTT TTTAGACCCC ACGCTCAATA ATAAAGCGTT CAACACCCCT 480TATAGCGCCT CAAAAACCAC CCTTGGGCCT AACGAACAGC TCGTTTTAAC CCAAGATTTA 540GGCACTCTTA GCATCATTAA AACCCTGACT TTTTATGATG ATTTGCATTA TTGA 594(2) SEQ ID NO 291 information

Sequence properties:

(A) length: 780 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...780

(xi) sequence representation: 291: ATGGCGTGTT GGCATAAAAG ATTGGCAGTT GGTTGTTGTA TCGTTTTATT GTCATGCGTA 60ATGAGTGCTA ATAATGTTAG TATCGTTAGA GACGATCCGC CCCTTGATCC AACGCTCCCT 120GCATGGATTT ATTCTGTTGC GTTATTGAAA GTGTATTTTA GCGATGGGAC TTATAAAGAA 180GGCTATGCGA CTTTGCTAGA AAACGGGCGT TATATCGCTT CTTCTGAAAC GCTCTATTCT 240AATGGCTTGT ATCCTAAAAT GATTTTAGCC AAAATGCAAG ACAGCAGTGC TAAAGAGCTG 300ATTTGCATAG CCAGCTTGCA CCTTGAAGCG ATGGATAGGG ATCAAGGGCT TTCGCTCTTA 360AAAACCGCCG ATTTTAGAGA CGATTATTGT CATAAAAGAG AAGAGAGCTA TTATCATGCA 420AGGATTTATG CCAAATACGC TCAAACTTTC CATTCAAATC CTTATACCAA TCAAAAAACA 480CCCACTTCCG ATCTCTACTA CCCGGCGTTA AATGAGGGGA ATTCTTTTTC CATACAGACA 540ACGGACATTT CTGTGGCTGA ACTTTTGAAA TCTAAAAAGT TTCTTTCGCT TGATGCTTCT 600TTTAAAAAGG GGAGCGTGTT GTGGGGAGGG AGGCCTTATT TTAGCGAGGT AGGGGAGTTT 660ATGGGAATGG CTAGCAGCAC TTTAGAAAAC CAAGAAAGTT TGGTGATTAT CCCTAAAGAA 720AAGATTGCGC GATTTTTAAG CGCTCTAAAA AATCAAAATA TTTTTCCAAA CATTCCCTAA 780(2) SEQ ID NO 292 information

Sequence properties:

(A) length: 2007 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2007

(xi) sequence representation: SEQ ID NO 292: ATGAAAAATC AACACAAAAA TCCCCTAACA AAAGCTTTAA TGAAAACTTA TCCATATAAC 60CATTTTTTAT TTTTCTGCTT TATTCTAGGA GCGTTTTTAT TAGGTTTGCT CAGTCCAGCT 120TATGCTTTAA GTATTATCAC CACTAAAGAA ATTGACGCTA ATTTGCTTAA TGGAGCGATA 180GAAAGCAGGG TGGTGTTAGG CAAGAGGGTG TTTAAAGTAG AAGCTCATGG GTTTTATTTT 240AGAAACAATG CGACTAACAG CATAGATATA GAAATCACCA GTCTTTTAAG AGACAATCAA 300TCGTTTCCTT TGACTAGCAG TGCTAAAACC AGTTTAAAAA TACCTCCTAA CGCCAAGATT 360AAAAAATCCA CTATCCTTGT TTTGAAAGGC GAGAACGCTG AAGAAGTGGC TAAGATTTTA 420GGCGTTAGCA AAGAAGAATA CCAAAAGCTA GAAAACATCG CTCAAACCAA AGCGGCTAAT 480GACCCTATGT ATGCTAACAC GCCTTTTAGT AATGGTTCTG ATAGTTCCTT TTACGATAAC 540AATCCTAATA GCCCTAGCAA TAACGCTATC AATGGCAAAG ATGGCGCAAA TGGGAGTAAC 600GGCTATGGGG CAAATGGCAA TGATGGGGTA AATGGGATCA GTGGGAGTAA TGGTGCAAAT 660GGGAGTCATT CAAATAATAA TGCAATAGGC AGTGGTATTG ATACAGATGG CGTGTTAGGG 720GTGGATGGGG TGAATGGCTC TAGTTCTTCA AGTGGCGGCT CTGTAGGGGG TTATGAGAAT 780AATTTCACTA ATCATGGCTC TACTAACAAT AACACAGGAG GGTATGACAA TTTTAATAAT 840GGCAGCTCAA GTGGTGGGAG TTTAGGGAAT GGGGGGCTTT TCCCTATTCC TTTTGGTAAT 900GGAGACACAA ACAATTCCAA TAATTCCACT AACACCACTA GCCCAACTAA TGGCAGTAGT 960TCTAATAACG CCACTAATCC TAGTTCGCAA GAAAACAATT ACTCCAGCCA GTATTGTAAA 1020GTGCCAGAGT TAAGCCCCAA CAACACGATG AAACTAGATG TTATCGCTAA AGATGGCTCT 1080TGTATTTCTA TGAACGCTTT AAGAGATGAC ACTAAATGCG CTTATAGATA CGATTTTGAA 1140GCCGGTAAAG CCATCAAGCA AACGCAATAC TACTATGTAG ATAGGGAAAA TAAAACGCAA 1200AATATCGGTG GTTGTGTGGA TTTACAAGGC GCTCAATACG CCATGCAACT TTACAAAGAT 1260GACAGCAAAT GCGCCTTACA AACCACGAGC GATAAAGGTT ATGGTATGGG GAAAACGCAA 1320ACCTTTCAAA CTGAAATCGT GTTTCGTGGG ATGGACAATT TAATCCATGT CGCTGTGCCT 1380TGCAGCGATT ATGCAAGGGT GCAAGACAGG ATTGTTAGGT ATGAAAAAAA TGATAAAACC 1440CAAACCTTAA CGCCTATAGT GGATCAGTAT TATAATGATC CTAACAACCC TAACAAGCAA 1500GAGATTTTAA ATCGTGGGAT TGCCACCCAA TTAAGCTCGC AATATCAAGA ATTTGCATGC 1560GGTCAATGGG AATACAATGA CGCTAAATTA GAAGCCAAAA GACCTACAAT GCTAAAAAGC 1620TATAACAAGC TTAATGGAGA ATGGGTAGAA GTTACGCCCT GTAATTTTGA AGCAGGGATT 1680AAAAGCGGTG CGGTTGTTAG CCCTTATGTG ATGGGCGTGC CTAGTTCTAA AGTCTTAAGC 1740GATATTACTA CAAGCCATTA TTTTAGGATA GAAAGGAAAA ATTATGGTGA GAGAGAACAA 1800TGCCAAAAAC TTTATGGAGT CAATCGTTGC CAACCGCAAT ATTCCATACT GATCCTAGTA 1860TCACCGATTG GAGCGCCACT TACAAAACCA CTACCACCCA AACCACTCAA CCTTATTTAC 1920GCCCAGCCCA AGATAATGAA AAACACCCCA CAACCTATAA TCTTATCACC ACTCAAACCA 1980CCATCAACAG GACTCAAAGC GTTTTGA 2007(2) SEQ ID NO 293 information

Sequence properties:

(A) length: 987 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...987

(xi) sequence representation: SEQ ID NO 293: ATGACTTATA AAGAACGACT CATACACGAA AAAATATTAA ACCAAAACGA CAAGGGTTTT 60AAAACAGAAC TGCGCATTTT GAGCGTTTTT ATCGTGGAAT TTTTGGTGAA TATTCTAGGG 120TTTATGTTGG CTAAAATGCC TCATTTTTGG TTTTTAAGGT GCGTTAAAGC TTTAGCGTGG 180CTCATGAAAA CTTTTGATAG GCGCCGTTAT TTTGACGCTA AGGCCAATTT GGATTTTGTG 240TTTGGGGATT CTAAAAGCGA AGAAGAAAAA AAAAGGATCA TTAAAAAGGG GTATGAAAAT 300TTTGCTTTCA TTATTTTAGA AACCATTAGA GTGATCTTTA TCCCTAAAGA TGAATACGAC 360GCTCGTTTCA CGCTCATCAA TGAAGAAAAC GTGTGGAAGT CCTTAAACAA GGAAGGCCAA 420GCGATCACTT TGTGCATGCA TTTTGGCTAT TGGGAAGCGG TAGGCACGAC TTTGGCGCAA 480TATTATGAAA ATTATGGTAG GGGGTGTTTG GGGCGTTTGA CTAAATTCGC TCCCATCAAT 540CACATGATCA TGAGTAGGCG AGAGGCGTTT GGGGTGCGTT TTGTCAATAA AATAGGGGCG 600ATGAAAGAAC TCATTAAAAT GTATAATCAA GGCAATGGCC TGGTGGGGAT TTTAGTGGAT 660CAAAATGTCG TGCCTAAAGA CGGGGTGGTG GTGAAATTTT TCAATAAAGA CGCTACGACC 730ACCACGATCG CTTCTATTTT GTCGCGCCGT TACAATATAG ACATTCAGCC GGTATTCATT 780GATTTTAACG ATGATTATTC GCATTACACA GCGACTTATT ACCCAAGTAT CCGCTCTCAA 840ATCACTGATA ACGCGCAAAA CGATATTTTA GAATGCACGC AAGCCCAAGC GAGTTTGTGC 900GAAGAGGTGA TTAGAAACCA CCCGGAAAGT TATTTTTGGT TCCACAGGCG TTTTAAAAGC 960ACCCACCCTG AGATTTATCA AAGATAG 987(2) SEQ ID NO 294 information

Sequence properties:

(A) length: 417 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...417

(xi) sequence representation: SEQ ID NO 294: ATGTTATATC TAAGGAAAGA AAATGGGGTT AGGACACTAA TAAGTTTAGG GATTTTGTTA 60AGCGTTTTGA ATGGCGATGA TCTGAGATTG TATTCAAAAC CTTTGGTCTA TTCGGCTGGA 120AGTGGGATTA TTGGGATTGA TATTGACAAA CGGACATTCT ATAAACGAGC GTTCGCTTTC 180ACGATGAAAT CGTTGTTTGG TGAAAACTTG CTTTTGTTTG TTAAATTGAA GCATTCTGCG 240TTGATGAGCA AACACATGAA AGGGCCTTTA GAAAACCGCC ACCACCATTC TTTCGCTAAA 300AATTATGAAA AAGCGGTTAA TGGTTGTCAA AAATATGTCC ATATCAAATT GCCTGAAGGC 360GCTCCTAGCA ACTTCCAATC AGGCTCATAC ATGGCGACTA TGGTGATGCG TTTTTAA 417(2) SEQ ID NO 295 information

Sequence properties:

(A) length: 987 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...987

(xi) sequence representation: SEQ ID NO 295: ATGCGTAAGG TTTTATACGC TCTCATGGGC TTTTTGTTGG TTTTTAGTGC TTTAAAAGCC 60GATGATTTTT TAGAAGAAGC GAACGAAACA GCCCCAGCGA ATTTAAACCA CCCCATGCAG 120GATTTAAACG CCATTCAAGG GAGCTTTTTT GACAAAAACC GCTCCAAAAT GTCCAACACT 180TTGAACATTG ATTACTTTCA AGGGCAAACT TATAAAATCC GCTTGCGTTA TGCGATGGCG 240ACTTTATTGT TTTTTTCAAA ACCCATTAGC GATTTTGTTT TGGGGGATAA GGTGGGTTTT 300GATGCGAAAA TTTTAGAAAG CAATGATCGC ATTTTACTCA TCAAACCCTT ACAAATCGGC 360GTGGATTCTA ATATCAGCGT GATTGATAGC GAGGGTAAGA TTTTTTCTTT CTATGTGTTT 420TCTACCACTT TCACCAGCTC CAAACACCCT AATTTACAGG TTTTTATAGA AGATAAAAAC 480TATTACACTA ACGCTTTTAT CAAGCCCCAA AAAGAAAATC AAGAAAATAT GTCTGAAAAT 540GCCCCTAAAG ATGCCCAAAA AAATAATAAG CCCCTAAAAG AAGAAAAAGA AGAAACTAAA 600GAAAAAGAAG AAGAGACTAT AATTATTGGC GATAACACCA ACGCGATGAA AATTATTAAA 660AAAGACATCC AAAAAGGCTA TAAGGCTTTA AAAAGCTCTC AAAGGAAATG GTATTGTTTA 720TGGGCTTGTT CTAAAAAATC CAAACTCTCC TTAATGCCTA AAGAAATCTT TAACGACAAG 780CAATTCACTT ATTTCAAATT TGACAAAAGA TTAGCACTCT CTAAATTCCC GGTGATTTAT 840AAGGTCGTTG ATGGTTATGA TAATCCGGTG AATACAAGGA TTGTGGGCGA TTACATTATC 900GCTGAAGACG TTTCTACTAA ATGGACTTTA AGGTTGGGTA AGGATTATCT GTGTATCCGT 960TTTGTCAAAA GGCGCAAAGG TGAATAA 987(2) SEQ ID NO 296 information

Sequence properties:

(A) length: 1008 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1008

(xi) sequence representation: SEQ ID NO 296: GTGATGTTTC ACAAAGCCCT TATTACCTTT ATCGTTCTAT GGTTTTTTTT GAATGGCTTA 60GGGGCTTATG ATTTCAAGCA TTGTCAGGCT TTTTTTAAAA AAGCGAGCCT TCAAAAAGGG 120GGCGTGGCTT TAAAGGAATT GCCTAAGGGC GTGTATTTGT ATTATTCTAA AACCTACCCC 180AAACACGCTA AAGTCATCAA ATCCGATCCT TTTATAGGGC TGTATTTGTT GCAAAGCGCG 240CCAAGCGAGT ATGTTTATAC ATTAAGGGAT TTAGACAAAG ACGCCCTTAT AAGACCCATG 300GCCAGTATAG GGGCTAATCA AGCCACAGAA GCGCGATTAT TGGTAGGGCA AAAAGGCTAT 360GACCGCTACG CTCAAATTTC ACAAAAAACC CAAAAAAATG GCGTTATCAG CAATATTTGT 420TATCAAATGC TAGGGCTAGG GGTAGGGGGG AACGGCTTTA TAGAAACGAA ATTCATCAAG 480CGCTTTTTAA ACCAACAAGA GCCTTATTAT GGGGATATTG GGGTGCGTTT AGAAGAACGT 540CATAAGCGTT TGGTGGTAGC GCAATTTGAT CCCTTTTTCC CTAAAAACCC TTTTTTAAAA 600AACGATGAAA TCCTAGCGAT CAATGATTAC AAGATCCACT CGTTAGCGGA GTTTGAATGG 660GTGGTGAGCA ATCTTTCATA CCAAAGCCTC GCCAAAGTGA AAATCAAACG AAACCATCAA 720ATCAAAGAAG TAACGCTCAA AGTCAATAAA CGCTATGGGG GGTTTTTGCT CAAAGACACT 780TTTTTAGAGC GCTATGGCAT CGCTTTAGAC GAGCGTTTTA TCATCACTAA AATAGGCGCT 840CATTTGCCCA AAGGCTTGGA TTTTTTAAAG CTTGGGGATA GGATTTTATG GGTGAATCAT 900AGAAGCGTTT CGTTCAACCC GAAAGCTTTA AGAGAAGCGT TAAGCACGCC TAAAATTGAA 960TTATTAGTCT GGCGTCAAGG CTTTGAATTT TACATTAAAG TCCGTTGA 1008(2) SEQ ID NO 297 information

Sequence properties:

(A) length: 753 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...753

(xi) sequence representation: SEQ ID NO:297: ATGCTAGGAA GCGTTAAAAA AACCCTTTTT GGGGTCTTGT GTTTGGGCGC GTTGTGTTTG 60AGAGGGTTAA TGGCAGAGCC AGACGCTAAA GAACTTGTTA GTTTAGGTAT AGAGAGCGTG 120AAGAAACAAG ATTTCGCTCA AGCTAAAGCG CATTTTGAAA AAGCGTGTGA GTTAAAAGAA 180GGTTTTGGGT GTGTTTTTTT AGGGGCGTTT TATGAAGAAG GGAAAGGAGT GGGAAAAGAC 240TTGAAAAAAG CCATTCAATT TTACACTAAA GGTTGTGAAT TAAATGATGG TTATGGGTGT 300CGCCTACTAG GAAATTTATA CTATAACGGA CAAGGCGTTT CTAAAGACGC CAAAAAAGCC 360TCACAATATT ACTCTAAATC TTGTGAATTG AACCATGCTG AAGGGTGTAC GGTCTTAGGA 420AGCCTACACC ATTATGGCGT AGGCACGCCT AAGGATTTAA GAAAGGCTCT TGATTTGTAT 480GAAAAAGCTT GCGATTTAAA AGACAGCCCT GGGTGTATTA ATGCAGGATA CATGTATGGT 540GTGGCAAAGA ATTTTAAGGA GGCTATCGTT CGTTATTCTA AAGCATGCGA ATTAAAAGAT 600GGTAGGGGGT GCTATAATTT AGGGGTTATG CAATACAACG CCCAAGGCAC AGCAAAGGAC 660GAAAAGCAAG CGGTAGAAAA CTTTAAAAAA GGCTGCAAAT CAAGCGTTAA AGAAGCATGC 720GACGCTCTCA AGGAATTAAA AATAGAGCTT TAG 753(2) SEQ ID NO:298 information

Sequence properties:

(A) length: 372 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...372

(xi) sequence representation: SEQ ID NO 298: ATGCGTTTAT TGATCGCGCT AGTTTTGTTC TTATGGTGGT TAAATTTAGG CGCTAAAGAA 60GCGGATTTCA TCTCTGATTG GGAATACGGA CTGGCCCTTT ATAAAAACCC TAGGGGTGTT 120GCGTGCGCAA AATGCCATGG CATTAAAGGC GAACAACAAG AAATCACCTT TTATTATGAA 180AAAGGCGAAA AAAAAATCCT TTACGCCCCT AAAATCAACC ATTTGGATTT TAAAACCTTT 240AAAGACGCCT TGAGTTTGGG CAAAGGCATG ATGCCTAAAT ACAACCTGAA TTTAGAAGAA 300ATCCAAGCGA TTTACCTTTA CATCACCTCT TTAGGGCATA AAGACGAGCG TAAGGATCCT 360TCCAAGCCTT AA 372(2) SEQ ID NO 299 information

Sequence properties:

(A) length: 543 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...543

(xi) sequence representation: SEQ ID NO 299: ATGTTAAACA AGTTTAAAAA AATCGTTGGC GTGGGTGTGT TAGTGGGCTG TTTAGGGGTT 60TTGCAAGCTA AAAACAGCTT ATTTGTCTTA CCTTATGAGC AAAGAGACGC TCTCAATTCT 120TTAATTTCTG GGATTAGCAG CGCTAGAGAG AACGTGAAAA TCGCTATTTA TAGTTTCACG 180CACAGAGATA TTGCAAGAGC GATTAAAAGC GTAGCGAGTA GGGGGATTAA GGTGCAAATC 240ATTTATGATT ATGAAAGCAA TCACAATAAC AAGCAATCCA CTATTGGCTA TTTAGACAAA 300TACCCTAACA CGAAAGTGTG CTTATTAAAG GGGCTTAAGG CTAAAAACGG GAATTATTAC 360GGCATCATGC ACCAAAAAGT AGCGATCATT GATGATAAAA TCGTGTTTTT AGGCTCAGCG 420AATTGGAGCA AAAACGCTTT TGAAAACAAT TATGAAGTGC TTCTAAAAAC CGATGACACA 480GAGACGATCC TCAAAGCCAA GAGTTATTAT CAAAAGATGC TAGAAGGTTG CGTTGGGTTT 540TAA 543(2) SEQ ID NO 300 information

Sequence properties:

(A) length: 423 base pair

(B) Type (2): nucleic acids

(C) Chaintype: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...423

(xi) sequence representation: SEQ ID NO 300: ATGAGAAGGA GTTTGGCTTT TTGCCTTTTA GCTTTGCTTG GATTACAGGT TTTAGGTGCT 60AGAGACTTTT CGCAACTCAA AAACGAAGAA CTTTTAAAAT TAGCAGGAAC TCTGCCTTCT 120AATGAAGCGA TTGATTATCG CATGGAAGTG TCTAAACGCC TTAAAGCCTT AAGTGCTGAA 180GACGCTAAGA AATTCCGCGC GAATTTCAGC CGGATCGCTA GGAAGAATCT TTCTAAAATG 240AGCGAAGAGG ATTTCAAAAA AATGCGTGAA GAAGTGCGTA AAGAATTAGA AGAAAAAACC 300AAAGGTCTAA GCGCTGAAGA AATCAAGGCA AAAGGACTTA ATGTGAGCGT TTGCAGCGGC 360GATACGAGAA AAGTTTGGTG TAGGGCTGTT AAGAAAAAAG ACGAACATTG CTCTCCTAAG 420TGA 423(2) SEQ ID NO 301 information

Sequence properties:

(A) length: 459 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...459

(xi) sequence representation: SEQ ID NO 301: ATGAAAAAAG CGTTGAAAAT ACTTTCTGTT GGCGCGTTGC TATTTGTGGC TTTAAACGCC 60AAAGATTTCA GCAAAACAAG CGATGAAGAT TTGGCTAAAA TGGCTGGCGT TGTCGCTCCG 120CAGGATATTG TGGATTACAC AAAAGAGTTG AAAAAGCGCA TGGAAAAGAT GCCTGAAGAC 180AAGAGAAAGG CGTTCCATAA ACAATTGCAT GAATACGCGA CTAAAAACAC AGACAAAATG 240ACCGTGGCGG ATTTTGAAGC CCGCCAAAAA GCCATTAAAG AAGCGCTTAA AAAAGGCAAT 300ATGGAAGACA TGGATGATGA TTTTGGGTTG AGATCATGCA AGCATGGGAA AAAGCACAAA 360CACGATAAGC ATGGCAAGAA GCATGGCAAA AAACATGACA AAGATCATGA CGATAAAGAC 420CATGACCACC ATGATGAAGA TCACAGCGAT AAGCACTAA 459(2) SEQ ID NO 302 information

Sequence properties:

(A) length: 423 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...423

(xi) sequence representation: SEQ ID NO 302: ATGCTAAAAA AGTTATTGCT CATTTCACTA TTTTTAGGGT TTTTAAGAGC AGAGGGCGAA 60CATTATGAAA TCATCGCTGA ACTTTCCAAG GCTTTTTTGA AAGCCAAAGA GGTTTTGACT 120GCGATCAATA AAACCTGTAT TGAAACCGGG CATGATCGCA CTCAAATACG CCTTCAAAAC 180GATTTTTTAG AGAATTTGTC TCAAACAGAG CAACAATTTG ATGATTATTT TGAAAAGGAT 240TTTAAAAGCG TAGGGGTTTT AAAAACCTTG CTTAAAGACA TCCAATCCTT AGAAAAAACT 300TCCAACAAGC TCGTATGCGT TGCCCCAAAA AACGCTAAAA ATTTTGAAAT ATTAGAGGGA 360GCGATAACGC AAATCATAGG ATTAGAAGAG CAGATGAATC AATTTATCAA TGGCGCGAAA 420TAA 423(2) SEQ ID NO 303 information

Sequence properties:

(A) length: 201 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...201

(xi) sequence representation: SEQ ID NO 303: TTGAGTGGGG AACTGAGATT GTCTTGGTGG TTAGTGGCTC GTTGCAAAAC ATTGTTCGTT 60CTTTTTTGCG AAGGATCAGC GTTTTCTTCA TTATTGATTT CATCAATTTT ATTTTCGTTA 120TTGATCAGAT CATTCACTTC TTTGGTGACT TTTTCATCTT CTTCTTCATG CTCAATCTTT 180TTTATATCCT TATTAGGTTG A201 (2) SEQ ID NO 304 information

Sequence properties:

(A) length: 270 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...270

(xi) sequence representation: SEQ ID NO 304: TTGGTGGTTA GTGGCTCGTT GCAAAACATT GTTCGTTCTT TTTTGCGAAG GATCAGCGTT 60TTCTTCATTA TTGATTTCAT CAATTTTATT TTCGTTATTG ATCAGATCAT TCACTTCTTT 120GGTGACTTTT TCATCTTCTT CTTCATGCTC AATCTTTTTT ATATCCTTAT TAGGTTGATT 180GATTTGATTG TTTTGAGTGG TTTTAGTGTT GTTTTGGTGC GATTGGGAYG ATTTTTTAGG 240CTCATCTTTG CATGCGCTCA ACACGCTTAA 270(2) SEQ ID NO 305 information

Sequence properties:

(A) length: 357 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...357

(xi) sequence representation: SEQ ID NO 305: ATGAAAAAAT CCCTTTGTTT GTCTTTCTTT CTGACCTTCT CTAACCCTCT TCAAGCCCTT 60GTCATTGAGC TTTTAGAAGA GATTAAAACT TCGCCGCATA AAGGCACTTT TAAGGCTAAA 120GTCCTTGATT CTAAAGAACC AAGACAAGTT TTAGGCGTTT ATAATATCTC CCCACACAAA 180AAACTCACGC TCACTATCAC TCACATATCC ACGGCAATCG TCTATCAACC CCTTGATGAA 240AAACTTTCTT TAGAAACGAC CTTAAGCCCT AACCGCCCTA CTATCCCTAG AAACACCCAA 300ATCGTTTTTT CTTCAAAAGA ATTGAAAGAA CCGCACTCAA ACCCAATACC TTCTTAA 357(2) information SEQ ID NO 306

Sequence properties:

(A) length: 738 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...738

(xi) sequence representation: SEQ ID NO 306: TTGAAAGCGT TTCAAACTTT TGGCGTGTTT GGGACAAGCG TGATCACTTG CATCACCGCT 60CAAAACACAC AGGGCGTGCA TGGGGTGTAT CCATTGAGTG TAGAGAGCGT GAAAGCGCAA 120ATCCTAGCTA TTAGAGATGA TTTTTCGATC AAGGCGTTCA AAATGGGGGC GTTATGCAAC 180GCTCAAATCA TTGAATGCGT AGCGAACGCT TTAGAAACTT GTGATTTTGG GTTGTGCGTT 240TTAGATCCGG TGATGGTGGC AAAGAATGGG GCTTTGCTTT TAGAAGAGGA GGCGATTTTA 300AGCTTAAAAA AACGCCTTTT ACCTAAAACC AATTTACTAA CCCCTAACCT CCCTGAAGTC 360TATGCGCTCA CAGGCGTTCA AGCGCGAGAC GATAAAAGCG CTTCAAAAGC GATGGGTGTT 420TTAAGGGATT TAGGCGTTAA AAACGCTGTG ATTAAAGGGG GGCATACAGA ACATTTTCAA 480GGGGAATTTA GCAACGATTG GGTGTTTTTA GAAGACGCTG AATTTACTTT AAGCGCCAAG 540CGATTCAACA CCAAAAACAC GCATGGCACG GGTTGTACTT TGTCTAGCTT GATTGTGGGC 600TTACTCGCTC AAGGGCTGGA TTTAAAAAAC GCTATCACAA AGGCTAAAGA GCTTTTAACT 660ATCATCATTC AAAACCCCTT AAACATTGGG CATGGGCATG GGCCTTTGAA TTTGTGGAGC 720ATCAAAAAGC ATGTTTGA 738(2) SEQ ID NO 307 information

Sequence properties:

(A) length: 642 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: isfree of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...642

(xi) sequence representation: SEQ ID NO 307: GTGCTAGAAA AACAAGATAA AGACCTTTTT CTTTTGCAAG TGGGTAACAG GATTATCCCC 60ACCAAAAGCG AACAGGAATT AAAAATCAAT CAGCCTTATT TTGCGACTAT GCAAAGAAAT 120CAGCTGGGCG ACATTGTGCT TAAAAATTTA GTGCCTGCCC CAAAAATCTT AGACGCATTG 180GACGATTTGC CCGTTATTGA AATGAAGAAA TTAAAAGAAA TATTGAGCGC CAAAGACAAC 240ACCCCCCTAA AAGAATACAA AGAACTTTTG AGCGAAAAAT TAATCCATGC TAAAAGCTCG 300CAAGAGTTTT TGAATACAGC CAACATGCTT TTAAGCTTGC AATCGCAGGT TTTAAGCTTT 360GTGGTTGAAA ACGAACGCAA AAAAGCTTTT TTACAGATGA AAGCCAAAAA ACAAAGCGTT 420GATTTTTACG CTCTGTACCC TAACTTGGGC GAAATTGGCG GCGTTATTTA TTTAAAAGAA 480AAAGAGAAAC AGCTTTTTTT AAAAACCACC CTCCAAAGGA CCAAAGAGGT TTTAAAAGAG 540GCTCAAAACA CCCTTTTAGG CTTTTCTTTT GTGGAAATTG TGTGCGAAAA AACCCCCATG 600CTTTTTGCCT TTGAAGATCG CTTATTGGAC ACGCTAGGGT AA 642(2) information SEQ ID NO 308

Sequence properties:

(A) length: 276 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...276

(xi) sequence representation: SEQ ID NO 308: ATGTCAGATG AAATCACGCA AGAAAACGAG TTAGAAATTA ACTCCAATAA TCAAAACCAA 60GAGCCAAAGG AAGTAGAAAA AATGCCATTG AATAATATTC AAAAAGCTAA GAAATTAAAA 120AACCACGCCA ATTTAATTGT TCGACGCACT GATGAGTTAG ATAAGGTTAT CAATAAGCGT 180GAAAGCTTGC AAAGAGAGTT TAAAAGACGC ATTAAGCACT TGGATAACAA GATTGAAACG 240CTTAGTAACA ATATTGAAGA ATTAAAAAGA AAGTAA 276(2) SEQ ID NO 309 information

Sequence properties:

(A) length: 519 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...519

(xi) sequence representation: SEQ ID NO 309: ATGAAAAAAT ATCAAAACAA ACGAAAGCTG GGTAAGCGTA TCAATTGCTT TATTTCAAAT 60GAATGTAAGG ACATTTTAGA AAATTATTTA AAAGTCAAAA AAATTAGCGT TACTGAGTGT 120ATAGAAAGCC TTTTATTAGC CCTAGACCCT AGCAAAGAAA CACTAAGAGC AAGGGATTTT 180TATGAAAGTT TGTTTAAAGT CATCAGTCTT AACCAACATG TCTATAAAGA ACTCATGGCT 240AATGGTAATA ACATTAACCA AATAGCCAAG AACACCAACA TTGCCATTAA GTATAACAAG 300CCCTTTTATT TGCAGAATTT AGCATTCTTA GAAGAGATTT TTAAGGTTAT GGATACACTT 360AATAAAAATG TAGAAGAATG TAAAAAAATC TCTTTGGAAT TATTACTTCA AATTTACAAA 420GAACAAAAAA GCCAAACAGA ATTTAACGCC ATTTCAAAAA TTCTCAACGC TCTTAATGAA 480AAACAATCTA CTACTGAGCC AAAAAAGGAC AACGCATGA 519(2) SEQ ID NO 310 information

Sequence properties:

(A) length: 963 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...963

(xi) sequence representation: SEQ ID NO 310: ATGAACACTA ATTTAAAGAA AGCCTTGTTT TTAACTACTC TTGGTTATTT GCAAGCTAAT 60GAGGGCTTTT TAGCCATTAT GCCTGATGAA AATAAACAAG AAGACATTTC TCAAGAACAG 120AAATTAGAAC ACAAAATGGA GCAAAAAATT GCTCCACAAA ATACCCTTAA AAAGCAACAA 180TCAGCTCCTT TACAAAGTGC TGAGTTGTTA CAAAGTCAAG TTAAAAGAGA AGTTAAAGAG 240CAAAAAAAGT CTCAAAAACA CCTAGTAGCT ATGCAAACTA AAAATGGCTT TTTCTTAGGC 300TCAGAAATTG CTATTACAGG CACAAGTTTA AAACAAAGTT TAAGCCTTAT TTCTAATGCT 360ACAGATGATT TACTCACTTA TAGCAAGACT TCTAAAAACG CTAATTTTAA TATGGGACTA 420TTAATAGGTT ATCAGCATTA TTTTGGAGCT AGTAAAAGGC ATGGGATTAA AATCTCAAGC 480CATTTGTATG GAGGCACACC TAGTGATGTA AGCACAGACA TAAAAATTTA CAAATCTAAA 540GTTAGCACCA ATTACACGCC TTTAAATTTT GGCATAGATG TGAAGTATTT GTTTGATTTT 600TTAAATGTCA TTAAAAAGAA CCGCCATACA CTAGGATTAA GTGTGGGCTT TGGCTGGCGT 660ATGCAATATT ATTTTGCAAA AATAGACCCC ATAAAAACCA GCCATAGTGA GTTTATCACT 720AATAAACCTA AAGATATTTT TAATCATGGT TTTTATCCCA CTATTGGACT ACATTATTAC 780TTAAACCATC ATCAATTTGA AGTGAATTAT CGCTTTGGAG GAGCAATTAA CTATCAGTCA 840GTTGTGCCTA GCAAAATTGT CGTTCAAAAC GGGAATTTTA AGGGCGAGGT CTTGTTTTCT 900AATTTTCTTA CCAAAGCGAC TAATTCTAGC TACATAGCGT TCAACTACGC TTATTTATTT 960TAA 963(2) SEQ ID NO 311 information

Sequence properties:

(A) length: 1461 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1461

(xi) sequence representation: 311 SEQ ID NO 311: TTGGCTATTA AAAGGGAAAA AATGAAAAAT AGCGCGCCTT TAAAGAATAA AGTTTTTTGT 60GGGTTATACG TTTTAAGTTT AAGCGCTTCT GTGCAAGCGT TTGATTATAA AATTGAAGTT 120TTGGCAGAGT CCTTTTCTAA AGTTGGCTTT AATAAAAAAA AGATTGACAT AGCTAGGGGG 180ATTTATCCTA CAGAGACTTT TGTAACCGCT GTGGGTCAGG GCAATATTTA TGCGGATTTT 240TTATCCAAAA GCCTTAAAGA TCAAGGGCAT GTTTTAGAGG GAAAAGTCGG CGGCACAATC 300GGTGGGATTG CTTATGACAG CACGAAATTC AATCAAGGCG GATCGGTTAT TTATAATTAT 360ATCGGTTATT GGGATGGCTA TTTAGGGGGT AAAAGGGCCT TGCTTGATGG CACGAGTATC 420CATGAGTGCG CGCTTGGCTC TGATGGCAAG GTGATTGATT CTATAGCGTG CGGGAACGCT 480AGAGCCAATA AAATCCGCCG TAATTACTTG ATGAATAACG CTTTTTTAGA ATACCGCTAT 540AAGGATATAT TTGCGGCTAA AGGGGGGCGT TATCAATCCA ATGCTCCTTA TATGAGCTCT 600TATACGCAAG GCTTTGAAAT CAGCGCTAAA ATCAAGGATA AAAATGAGGG GAGCCATAAA 660TTATGGTGGT TTAGCTCATG GGGTAGGGCG TTCGCTTATG GGGAGTGGAT TTATGATTTT 720TACTCTCCAA GAACCGTGAT TAAAAACGGG CGCACTCTAA ATTATGGTAT CCATTTAGTG 780GATTACACTT ACGAAAGGAA AGGGGTTAGC GTCAGCCCCT TTTTCCAGTT TTCGCCCGGG 840ACTTATTATA GCCCTGGGGT GGCTGTAGGC TATGATAGTA ACCCTAATTT TAATGGCGTG 900GGCTTTAGAT CCGAAACGAA GGCTTATATT TTGCTCCCTG TCCATGCCCC CCTTAAAAGG 960GATACTTATC GTTACGCTGT GAAAGCTGGC ACCGCTGGGC AAAGCCTGCT CATTAGGCAA 1020CGATTTGATT ACAATGAATT TAACTTTGGG GGAGCGTTTT ATAAAGTATG GAAAAACGCA 1080AACGCTTACA TAGGCACGAC AGGAAACCCT CTAGGCATTG ATTTTTGGAC CAATAGCGTT 1140TATGATATAG GGCAAGCCTT AAGCCATGTG GTAACCGCTG ATGCCGTCTC TGGTTGGGTT 1200TTTGGTGGAG GCGTGCATAA AAAATGGCTG TGGGGGACTT TGTGGCGTTG GACTAGCGGC 1260GCTTTAGCCA ATGAAGCGAG CGCGGCTGTT AATGTGGGCT ATAAGATCAG TAAGAGTTTG 1320ACAGCGAGCG TGAAATTAGA ATATTTGGGC GTGATGACGC ATTCAGGCTT TACGGTAGGG 1380AGTTACAGAC CCACGCCCGG CTCTAAAGCA CTTTATTCAG ACAGGAGCCA TCTAATGACA 1440ACCCTTAGCG CCAAATTCTA A1461 (2) SEQ ID NO 312 information

Sequence properties:

(A) length: 504 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...504

(xi) sequence representation: SEQ ID NO 312: GTGTGCATTA TTTTTGATGC AGACATAAAA AAAGAGAACC AAGAAAGCGA TGCAGGTTTT 60GATAACAAGC TTAAGCATAT TCGTGAAAAA TTCAAAGAAA AAGGGACTGA TTTTCCCAAA 120GAACAAATCT TTTTATTCCC TAACAATCAA GATGATGGCG ATTTAGAAAC CCTATTATTA 180GAAATTGCTA AACACGATGA ATTTCTTAAA TGCTTTGAAG GATACTTAGA ATGTATTAAA 240AGTAAAGAAC ATTATAAACC GATTAAAAAC ATAAGAAAAA ATATGCTGTA TGCCTATTTA 300GAAGCGCTTG GATTAGAGAA TTTGACCAAG ACCAATATAG ATGTTTTTGA TAGTAAAGGT 360AAAATAAAGA GTAGATATGA AGAAAACTAC AAAAAATTAA CAGAAGAAGT TATTGATTTC 420AGCTCGAATT CTCTCATTCC CCTTAAAAAT TTTCTAGGGC AATTCGCAGA AAATAAACAA 480AAAACAAATC CTAAAATTTT CTAA 504(2) SEQ ID NO 313 information

Sequence properties:

(A) length: 633 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...633

(xi) sequence representation: SEQ ID NO 313: ATGGTATTGA AAACAAAATT AAAAATTATA AGCTCGGTGA TTTTGAGTAC TTTATTGTGG 60GTGGGTTGCT CAAGCGAAAT GGCGACTTAT CAAAATGTGA ATGACGCCAC TAAAAATACG 120ACTGCAAGTA TTAATAGCAC GGATTTATTG CTAACCGCTA ACGCGATGTT AGATTCCATG 180TTTAGCGACC CTAATTTTGA GCAACTCAAG GGCAAGCATT TGATTGAAGT TTCAGATGTG 240ATTAACGACA CCACTCAGCC CAATTTGGAC ATGAATCTTT TGACGACCGA AATCGCGCGG 300CAGTTGCGAT TGCGATCTAA TGGGAGGTTC AATATCACAA GGGCGAGTGG AGGGAGTGGT 360ATTGAAGCAG ACAGCAGAAT GGTGAAACAG CGCGAAAAAG AACGAGAGAG CGAAGAGTAT 420AATCAAGACA CCACTGTAGA AAAAGGCACT TTAAAAGCCG CTGATTTATC TTTAAGTGGT 480AAAGTATCCA GTATCGCAGC CTCTATTAGT AGTTCTAGGC AACGCTTAGA CTACGACTTC 540ACCCTAAGCC TTACCAATAG GAAAACGGGT GAAGAGGTAT GGAGCGATGT TAAGCCTATT 600GTGAAAAATG CTAGCAATAA GCGTATGTTT TAA 633(2) SEQ ID NO 314 information

Sequence properties:

(A) length: 555 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...555

(xi) sequence representation: SEQ ID NO 314: ATGAAAGCTT TTTTAAAGAT TTGCATGGTT TTGATTTTTG TGGGTGTCGC TCATGCTAAA 60AATCCTTTAA CCCTTTCTAA AGAAGAAGAA GTTTTACAAA ATTTGCAAAG TTTTAGCGCG 120CATTTCAAGC AAGTGTTAAA AAATGAAAAG CCCTTAGTTT ATTATGGGGT TTTAAAGGCT 180AAAGCCCCTA ATTGGGCTTT ATGGGTTTAT GAAAAACCCT TAAAAAAAGA AATTTACATG 240AACGATAAGG AAGTGGTGGT TTATGAGCCT AATTTATTCC AAGCGACTAT CACGCCCTTA 300AAAGACAAGA CGGATTTTTT CACCATTCTC AAGCAATTGA AAAAGCAGAC TGACGGCTCT 360TTTAAAACGA CTATCAACAA GACCACTTAT CGTTTGGTTT TTAAAGACGG CAAGCCTTTT 420TCGTTGGAAT TTAAAGATGA CATGAATAAT CTTGTTACGA TCACTTTTTC TCAAGCAGAA 480ATCAACCCTA AAATTCCTAA TGAAATCTTT GTTTTTAACC CTAAAGATGA AAATATTGAT 540ATTGTACGCC AGTGA 555(2) SEQ ID NO 315 information

Sequence properties:

(A) length: 558 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...558

(xi) sequence representation: SEQ ID NO 315: ATGAGAATTA AGGCTTATTT TTTGCGTTTT ATCGCACTGG TTTTTATCGT TTTGTTGGGT 60TTTAGCGCTT GTAAAAACTC TCAAAAATCT CAAGATTCTC AAAACAATAC CACCCAACAA 120GATAGCCCTA AAACCTACAC CGCTATGGAT CTGAATAACC AAGAATACAC GATTATGGGC 180GATTTAGATT CTCTAAACAT CAGCCCGGAT CCTAACACCC CTACCCTATT GATTTTAAGC 240GCTTTAGATA ATTCTTTAAA AGATTACGCC CCCACCTTTA ACGTCTTAAA AAAAACTTTT 300AAAGATCGTT TGAGGGTGCT TATTTTACTC AATCAACCCT ATTCAAGCGA TGCAATCAAA 360GGCTTTATTG CGCCTTCTCA AACTGATTTG ATGATTTTAA ACCCTAAAGA TACCGCTCTT 420TTTGATCATT TAAACCATGA CGCTTTAAAC CATTCTTTTA ACATGCTCTT ATATGACAAA 480CACCAATTGA TTAAAATGTA TCAAGGGATC GTGCCAGCAG AAATGCTCCA ATTTGATATT 540TCCAATTTAA AGGACTGA 558(2) SEQ ID NO 316 information

Sequence properties:

(A) length: 1092 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1092

(xi) sequence representation: SEQ ID NO:316: ATGGTATCAA CACTCAAACC GCTAAAAATC GGTAAACACA CCATAAAATT CCCTATTTTT 60CAAGGGGGCA TGGGTGTGGG GATTAGCTGG GATGAACTAG CTGGAAATGT TGCCAAAGAA 120GGGGCTTTAG GAGTGATTTC AGCCGTAGGG ACTGGTTATT ATAAAAACAT GCGTTTTGTA 180GAAAGGATTG TGGCTAAAAA ACCCTTTGAA GCCTTGAATT TTTACTCCAA AAAAGCGTTG 240AATGAGATTT TTGCAAACGC TAGGAAAATT TGCGGGAACA AGCCTTTGGG GGCGAATATT300TTATACGCTA TCAATGACTA TGGCCGTGTT TTAAGGGACT CTTGTGAGGC GGGGGCGAAT 360ATTATCATTA CAGGGGCTGG TTTGCCCACT AACATGCCTG AATTCGCTAA GGATTTTAGC 420GATGTGGCGC TCATCCCTAT CATTTCCTCA GCGAAGGCTT TAAAAATCCT TTGTAAAAGA 480TGGAGCGATC GCTATAAAAG AATCCCGGAC GCATTCATTG TGGAAGGGCC TTTGAGTGGG 540GGGCATCAGG GCTTTAAATA CGAAGATTGT TTCAAAGAAG AATTCCAATT AGAAAACTTA 600GTGCCTAAAG TCGTGGAAGC TTCTAAAGAA TGGGGGAATA TCCCTATCAT CGCCGCGGGG 660GGGATTTGGG ATAAGAAAGA TATAGACACC ATGTTAAGCC TTGGAGCGAG TGGGGTGCAA 720ATGGCGACTC GTTTTTTAGG CACGAAAGAA TGCGACGCTA AAGCGTATGC CGATCTTTTG 780CCCACGCTCA AAAAAGAAGA TATTTTACTC ATCAAATCGC CTGTAGGCTA TCCGGCTAGG 840GCTATCAATA CGGGGGTGAT CAAACGCATT GAAGAGGGTA ACGCGCCTAA AATCGCATGC 900GTGAGCAATT GTGTAGCGCC TTGTAACAGG GGTGAAGAAG CTAAAAAGGT GGGCTATTGT 960ATCGCTGATG GTTTGGGGCG CAGTTATTTA GGAAACAGAG AAGAGGGGCT TTATTTTACC 1020GGGGCTAATG GCTATAGAGT GGATAAGATT ATCAGCGTGC ATGAATTGAT TAAAGAGCTT 1080ACAGAGGGTT AA 1092(2) SEQ ID NO:317 information.

Sequence properties:

(A) length: 1092 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1092

(xi) sequence representation: SEQ ID NO:317: ATGGTATCAA CACTCAAACC GCTAAAAATC GGTAAACACA CCATAAAATT CCCTATTTTT 60CAAGGGGGCA TGGGTGTGGG GATTAGCTGG GATGAACTAG CTGGAAATGT TGCCAAAGAA 120GGGGCTTTAG GAGTGATTTCAGCCGTAGGG ACTGGTTATT ATAAAAACAT GCGTTTTGTA 180GAAAGGATTG TGGCTAAAAA ACCCTTTGAA GCCTTGAATT TTTACTCCAA AAAAGCGTTG 240AATGAGATTT TTGCAAACGC TAGGAAAATT TGCGGGAACA AGCCTTTGGG GGCGAATATT 300TTATACGCTA TCAATGACTA TGGCCGTGTT TTAAGGGACT CTTGTGAGGC GGGGGCGAAT 360ATTATCATTA CAGGGGCTGG TTTGCCCACT AACATGCCTG AATTCGCTAA GGATTTTAGC 420GATGTGGCGC TCATCCCTAT CATTTCCTCA GCGAAGGCTT TAAAAATCCT TTGTAAAAGA 480TGGAGCGATC GCTATAAAAG AATCCCGGAC GCATTCATTG TGGAAGGGCC TTTGAGTGGG 540GGGCATCAGG GCTTTAAATA CGAAGATTGT TTCAAAGAAG AATTCCAATT AGAAAACTTA 600GTGCCTAAAG TCGTGGAAGC TTCTAAAGAA TGGGGGAATA TCCCTATCAT CGCCGCGGGG 660GGGATTTGGG ATAAGAAAGA TATAGACACC ATGTTAAGCC TTGGAGCGAG TGGGGTGCAA 720ATGGCGACTC GTTTTTTAGG CACGAAAGAA TGCGACGCTA AAGCGTATGC CGATCTTTTG 780CCCACGCTCA AAAAAGAAGA TATTTTACTC ATCAAATCGC CTGTAGGCTA TCCGGCTAGG 840GCTATCAATA CGGGGGTGAT CAAACGCATT GAAGAGGGTA ACGCGCCTAA AATCGCATGC 900GTGAGCAATT GTGTAGCGCC TTGTAACAGG GGTGAAGAAG CTAAAAAGGT GGGCTATTGT 960ATCGCTGATG GTTTGGGGCG CAGTTATTTA GGAAACAGAG AAGAGGGGCT TTATTTTACC 1020GGGGCTAATG GCTATAGAGT GGATAAGATT ATCAGCGTGC ATGAATTGAT TAAAGAGCTT 1080ACAGAGGGTT AA 1092(2) SEQ ID NO:318, information.

Sequence properties:

(A) length: 579 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...579

(xi) sequence representation: SEQ ID NO 318: TTGTTAGGGA GGAATGGCGT TACTTTAAAT ATCCGCCAGG TTTTTTGGTG GGATAATTTC 60AACTGGTCCA TTGGCTTTTA TAACACCTTT GGCAATTCAG ACGCTTTTTT AGGCTCTCAC 120ACCATGCCAA GGGGGAATAA CACTTCCTAT ATCAGTAATG AAATCTCAGT AACGACTAGG 180CATGCCGGAA TGATCGGCTA TGATTTTTGG GATAATACGG CTTATGATGG GCTGGCTGAT 240GCGATCACTA ACGCGAACAC TTTCACTTTT TACACTTCGG TTGGAGGGAT CCATAAGCGT 300 TTTGCATGGC ATGTTTTTGG GCGCGTCTCT CATGCGAATA AAAATGCGTT AGGGCAAGTG 360GGGAGGGCTA ATGAATATTC CTTGCAATTC AATGCGAGCT ATGCGTTCAC TGAATCGGTT 420CTCCTTAACT TTAGGATCAC TTATTATGGG GCTAGGATCA ATAAAGGGTA TCAAGCAGGG 480TATTTTGGAG CGCCCAAATT CAATAACCCG GATGGCGATT TTAGCGCTAA TTACCAAGAC 540AGAAGTTACA TGATGACCAA CCTCACGCTG AAGTTTTGA 579(2) SEQ ID NO 319 information

Sequence properties:

(A) length: 1065 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1065

(xi) sequence representation: SEQ ID NO 319: ATGCAACAAC AGCTCACCTA CTTGAATGCG GGGAATGTGT TTTTTAATGC GATGAATAAG 60GCTTTAGAGA AGAATGGGAC TGCTACTGCT AATAGCACTA GTAGCACTAG CGGTGCGACT 120GGTTCAGATG GTCAAACTTA CTCTCAACAA GCTATTCAAT ACCTTCAAGG CCAACAAAAT 180ATCTTAAATA ACGCAGCGAA CTTGCTCAAG CAAGATGAAT TGCTCCTAGA AGCTTTCAAC 240TCTGCCGTAG CTGCTAACAT TGGGAATAAG GAATTCAATT CAGCCGCTTT TACAGGTTTG 300GTGCAAGGCA TTATTGATCA ATCTCAATTG GTTTATAACG AGCTCACTAAAAACACCATT 360AGCGGGAGCG CGGTTAATAA CGCTGGGATA AACTCCAACC AAGCTAACGC TGTGCAAGGG 420CGTGCTAGTC AGCTCCCTAA CGCTCTTTAT AACGTGCAAG TAACTTTGGA TAAAATCAAC 480GCGCTCAACA ATCAGGTGAG AAGCATGCCT TACTTGCCCC AATTCAGAGC CGGGAACAGC 540CGTGCAACGA ATATTTTAAA CGGGTTTTAC ACTAAAGTGG GCTATAAGCA ATTCTTCGGG 600AAGAAAAGGA ATATCGGTTT GCGCTATTAT GGTTTCTTTT CTTATAACGG AGCGAGCGTG 660GGCTTTAGAT CCACTCAAAA TAATGTAGGG TTATACACTT ATGGGGTGGG GACTGATGTG 720TTGTATAACA TCTTTAGCCG CTCCTATCAA AACCGCTCTG TGGATATGGG CTTTTTTAGC 780GGTATCCAAT TAGCCGGTGA GACCTTCCAA TCCACGCTCA GAGATGACCC CAATGTGAAA 840TTGCATGGGA AAATCAATAA CACGCACTTC CAGTTCCTCT TTGACTTCGG TATGAGAATG 900AACTTCGGTA AGTTGGACGG GAAATCCAAC CGCCACAACC AGCACACGGT GGAATTTGGC 960GTAGTAGTGC CTACGATTTA TAACACTTAT TACAAATCAG CAGGGACTAC CGTGAAGTAT 1020TTCCGTCCTT ATAGCGTTTA TTGGTCTTAT GGGTATTCAT TCTAA 1065(2) SEQ ID NO 320 information

Sequence properties:

(A) length: 2247 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2247

(xi) sequence representation: 320: ATGGAAGACT TTTTGTATAA CACCTTATAT TTCATAGAGG ATTATAAGTT GGTTGTTATT 60TTTAGTTTCA TAGGGTTAAT AGCGTTATTT TTCCTCTACA AATTCATAAA AACTCAAAAA 120AAGGTTTTTA AAGATAAAGC TAACCAGCCT CAAAAGAAAA AAAGCTTTAA AGAAATCATT 180ATAGATGGGC TGAAAGAAAG GGTTAAAACC TTTGGCTTTT GGTTGCAAGC TATACTATTA 240CTATCCTATT CTTTTATCAC ATCAGGGTTA TTTTTCTTGA TTCTCTTAGG TAATTTTTAT 300GATGATAATA GATTGCCTGA GAGCGATGAT GATCTTTTTG ATATATGGGT CTATGCGATA 360CAAGATTTTC CTGCATACTA TTTTAAGGCA CTCACTTTTA GCTCGCTCAA GATTTATGGG 420TTCAATATAT CCTTAGTCGT ATATAGTTCT ATTTTATGCT CTTATATATT CATTACCTTT 480TTTGTGTGGT TCTTAAAATA CTTAACTCGG ACTAGGGACA TAGGAGCGAA TAAAAAAGTT 540GATGATCTCT TTGGTAGCGC GAGTTGGGAA ACTGAAGAGA AAATGATCAA AGCCAAGCTT 600ATCACACCCA ACAATAAAAA ACGCGCCTTT GACAAACGAG AGGTTATTGT AGGCAGGCGT 660GGCTTAGGGG ATTTTATCGC TTACGCAGGA CAGGCGTTTA TTGGCTTGAT TGCTCCTACT 720AGGAGCGGTA AGGGTGTGGG TTTCATCATG CCCAATATGA TCAATTACCC TCAAAATATC 780GTTGTGTTTG ATCCTAAGGC TGACACTATG GAAACTTGCG GGAAAATCAG AGAAAAACGC 840TTCAACCAAA AAGTGTTCAT CTATGAACCT TTCTCCTTAA AAACACACCG ATTTAATCCT 900TTCGCTTATG TGGATTTTGG TAATGATGTG GTTTTGACTG AAGACATACT CTCTCAAATT 960GACACACGCC TAAAAGGGCA TGGCATGGTG GCTAGTGGAG GGGATTTTTC CACTCAAATC 1020TTTGGATTGG CTAAGTTGGT GTTCCCTGAA AGACCTAATG AAAAAGATCC TTTTTTTAGC 1080AATCAGGCGC GAAACCTTTT TGTCATCAAT TGCAATATTT ATAGGGATCT CATGTGGACT 1140AAAAAGGGGC TTGAGTTTGT CAAAAGAAAA AAAATCATCA TGCCTGAAAC CCCCACGATG 1200TTTTTCATAG GTTCTATGGC AAGCGGTATC AACTTGATTG ATGAAGACAC AAACATGGAA 1260AAAGTCGTGT CTTTAATGGA ATTTTTTGGA GGTGAAGAAG ATAAGAGTGG CGACAATCTA 1320AGAGCGCTTA GTCCTGCCAC TAGAAACATG TGGAATAACT TCAAGACAAT GGGTGGCGCT 1380AAAGAAACTT ACAGCTCGGT TCAAGGGGTC TATACATCAG CGTTTGCGCC TTACAATAAC 1440GCCATGATCA GGAATTTCAC GAGCGCTAAT GATTTTGATT TCAGGCGTTT AAGGATCGAT 1500GCAGTGAGTA TTGGTGTGAT CGCTAATCCT AAAGAAAGCA CTATTGTTGG ACCGATATTA 1560GAGCTGTTTT TCAACGTGAT GATTTATAGC AATTTGATTC TGCCAATCCA TGATCCACAA 1620TGCAAAAGAA GCTGCTTGAT GCTCATGGAT GAATTTACGC TCTGTGGCTA TTTAGAGACC 1680TTTGTTAAAG CGGTAGGGAT CATGGCAGAA TACAACATGC GCCCCGCTTT TGTGTTTCAA 1740AGTAAGGCGC AATTAGAAAA CGACCCCCCA CTTGGTTATG GTAGGAATGG CGCTAAGACT 1800ATTTTAGACA ACCTTTCTTT GAATATGTAT TATGGGATCA ACAACGATAA CTACTATGAA 1860CATTTTGAAA AGCTTTCTAA AGTGTTAGGG AAATACACAA GGCAAGATGT GAGCCGGAGC 1920ATTGATGATA ATACGGGTAA GACCAACACT TCTATCAGCA ACAAGGAGCG GTTTTTGATG 1980ACCCCTGATG AATTGATGAC TATGGGCGAT GAGCTTATCA TTTTAGAAAA CACGCTCAAA 2040CCCATCAAGT GCCACAAGGC GCTTTACTAT GATGATCCCT TCTTCACCGA TGAGCTCATT 2100AAGGTGAGTC CAAGCTTGAG CAAGAAATAC AAATTGGGGA AAGTGCCTAA TCAAGCAACA 2160TTTTATGATG ACTTGCAAGC CGCTAAAACC AGAGGCGAAT TGAGCTATGA TAAATCTTTA 2220GTGCCTGTGG GTTCAAGCGA ACTGTGA 2247(2) SEQ ID NO 321 information

Sequence properties:

(A) length: 105 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...105

(xi) sequence representation: SEQ ID NO 321: TTGAGCCATT TATTTCTCGT AAAACGCCCT TACAGTCGCC TTTATTTACA TAATCAGAGC 60AACCATAAAA TGAGACACCA TTCAATCCTC TTTGTATCAT TTTAG 105(2) SEQ ID NO 322 information

Sequence properties:

(A) length: 333 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacterpylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...333

(xi) sequence representation: SEQ ID NO 322: ATGGAACACC ATAAAGCGCA CACAACCATT CAGGCTTTAC AAGCCAAACG CAAAAGGTTG 60CTAACCGAAT TAGCCGAGTT AGAAGCAGAA ATAAAGGTGA GCAGCGAACG AAGGAGCAGT 120TTTAACGTTT CGCTCTCGCC GAGTTTGTTA GCCGAAATAG AAGAGATAGA ATACGAAGAA 180AAAATGAGCA AAGAGCGAAG AATCCATCAC AATCTTTTGC TTTCGCCCAG TTTCATGGCT 240AAAGTGGATG AATACATGAA AGAGAAAGGT TTTCCTAATC GATCGCTTCT CTTTGAAAAA 300GCGTTGGAGT TTTATATGCT AAAACACCCA TAA 333(2) information of SEQ ID NO 323

Sequence properties:

(A) length: 477 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...477

(xi) sequence representation: SEQ ID NO 323: GTGATGCGTT TCTTTTCATT CTGTTATTTT TTATTTTATT TTTTAGGGGT TTCTTTGCAT 60GCCCTTAGCC CCCTAGAAGA ACAAGAATTT TTAATTTCGT ACCGCTTGAA AATCGTTGAT 120TCTAGAGTGA TGGGTGAAGA GTATTCTGTT TCTAAACCTA TCGTTAGTCG CATTAAAACA 180GCCCCCTATG TTTTAGACTA TCATTGCTCT ATCATCACTC GCAACTTGCC CGATTTGAAA 240AACCCCTTGC TCCAAATAAA GCTAGAACGC TTCCTTTTAG AAATAGCGTT AAAAAAAGAA 300AAAGAGCGAG TCATTGACTG CCTTTTAAAA AGCCAAGTCG CTATCACGCA TTATGATCAC 360AGCTATAAAA ACGGCACCAC TACCACAAGC ATTCTTAACC TCAAAGCCTT AAGCGTTAAA 420GCGAGTTTAG AGGGAGATAT GCTGTCTTTA GATATTTTTA GAAAGGAAGA AGAATGA 477(2) information of SEQ ID NO 324

Sequence properties:

(A) length: 351 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...351

(xi) sequence representation: SEQ ID NO 324: ATGGAGTTAA TTAAGAAATT GGAAAAAGAA AGCGAAGTTT TAAAGAAAGA TTTACAACAA 60CATTCAAACG AGCTTTTTAA AATGTTGATT ATTGATAATG AAGATTTGTT TAAAGAGCAA 120TTTGAGATTA TGTTTAAAGC ATGGGTTGAA ATCGTAAAAA TGATGTTTGA ATTAACCAAA 180AAAACCAAAT TTGATGGCGA AATGATTGGC TACACAGAAG AACTTTTAAC CTTTTTAGTT 240AGAGATTTTT TTAATGGGAT TTTTAAATCC AAAGTAATAC CTAAAATGCC TATTTTTTGC 300GGTGATGTTA AATGCGAAGA TTTTAATGCC CTAAGAAGTT TAGTTTATCT T351 (2) SEQ ID NO 325 information

Sequence properties:

(A) length: 834 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...834

(xi) sequence representation: SEQ ID NO 325: TTGAAACGAG CGTTATGGTT AATTTTAGGG CTTTTTTACG CGCTTAATGC AGAGAGCTTT 60AAAGATGTTT TGACTAAAGG GGATTACACT TTTTTTAATA AAAAGGTGGT TTCGCCTATC 120AAACGCTATG CGGATAGATC GGCGTTTTAT CTGGGGCTTG GGTATCAATT AGGGAGCATT 180CAGCACAACT CTAGCAACTT GAATTTATCC CAACGATTTA ATAAGAGTCA GATTATTTTC 240AGCGATAGTC TAAGCCCTGT TTTTAAAAAT TCGTATGTGT CTAATGGTCT TGGCGTTCAA 300GTGGGCTATA AGTGGGTGGG TAAGCATGAA GAGACGAAAT GGTTTGGCTT CAGGTGGGGG 360CTGTTTTATG ATTTGAGCGC TTCTCTTTAT GGCTCTCAAG AATCGCAGTC TATCATCATT 420TCCACTTACG GCACTTATAT GGATTTATTG CTTAACGCTT ATAATGGGGA TAAGTTTTTT 480GCCGGGTTCA ATCTGGGGAT CGCTTTTGCT GGAGTGTATG ACAGATTGAG CGATGCGTTA 540TTGTATCAAA CTCTTCTTCA AAACACTTTT GGCGGGAAAG TGAATTTAAA CGGCTTCCAG 600TTTTTGGTGG ATTTAGGGGT TCGTTTAGGG AATGAACACA ACCAATTTGG CTTTGGGATT 660AAAATCCCTA CTTATTATTT TAACCATTAT TATTCCATGA ATAACATTAG CAATAATAGT 720GAAAATGTCT TAAAAGTTTT ACGATTTTTA GAATACGGGA TCAACAGCTT GTTGTATCAA 780GTTGATTTCA GGCGCAATTA CTCGGTTTAT TTCAACTACA CTTATAGTTT TTAA 834(2) SEQ ID NO 326 information

Sequence properties:

(A) length: 1482 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ fFeature

(B) Position: 1...1482

(xi) sequence representation: SEQ ID NO 326: ATGCCTGCCT TGAATAGCTC CAAAAATATG GTAGTCAATA TCAATCAAAC TTTCACAAAA 60AACCCTACCA CAGAATACAC TTACCCCGAT GGGAATGGCA ATTATTATTC AGGCGGTTCA 120TCAATCCCAA TCCAGCTAAA GATTAGTAGC GTCAATGACG CTGAAAACCT TTTGCAACAA 180GCCGCTACTA TCATCAATGT CCTTACCACC CAAAACCCGC ATGTGAATGG TGGCGGTGGG 240GCATGGGGGT TTGGCGGTAA GACCGGGAAT GTGATGGATA TTTTTGGCGA TAGTTTTAAC 300GCTATTAACG AAATGATCAA AAACGCTCAA GCCGTTTTAG AAAAAACCCA ACAGCTTAAC 360GCTAATGAAA ACACCCAAAT CACGCAACCA GACAATTTCA ACCCCTACAC TTCTAAAGAC 420ACGCAGTTCG CTCAAGAAAT GCTCAATAGA GCTAACGCTC AAGCAGAGAT TTTGAGCTTA 480GCCCAACAAG TAGCGGACAA TTTCCACAGC ATTCAAGGGC CTATCCAACA AGATCTAGAA 540GAATGCACCG CAGGATCAGC TGGTGTGATT AACGACAACA CTTATGGTTC AGGTTGCGCG 600TTTGTGAAAG AGACTCTCAA TTCCTTAGAG CAACACACCG CTTATTATGG CAACCAGGTC 660AATCAGGATA GGGCTTTGTC TCAAACCATT TTGAATTTTA AAGAAGCCCT TAGCACTTTA 720GGGAACGACT CAAAAGCGAT CAATAGCGGT ATCTCTAACT TGCCTAACGC TAAGTCCCTT 780CAAAACATGA CGCATGCCAC TCAAAACCCT AATTCCCCAG AAGGTTTGCT CACTTATTCT 840TTGGATACCA GCAAATACAA CCAGCTCCAA ACTGTTGCGC AAGAATTAGG CAAAAACCCC 900TTTAGGCGCA TCGGCGTGAT TAACTATCAA AACAATAACG GGGCGATGAA CGGCATCGGC 960GTGCAAGCGG GCTATAAGCA ATTCTTTGGC AAAAAAAGGA ATTGGGGGTT AAGGTATTAT 1020GGTTTCTTTG ATTATAACCA TGCTTATATC AAATCTAATT TTTTTAACTC GGCTTCTGAT 1080GTGTGGACTT ATGGGGTGGG TATGGACGCG CTTTATAACT TCATCAACGA TAAAAACACC 1140AACTTTTTAG GCAAAAATAA CAAGCTTTCT GTGGGGCTTT TTGGTGGCTT TGCGTTAGCC 1200GGGACTTCGT GGCTTAATTC CCAACAAGTG AATTTGACCA TGATGAATGG CATTTATAAC 1260GCTAATGTCA GCGCTTCTAA CTTCCAATTT TTGTTTGATT TAGGCTTGAG AATGAACCTC 1320GCTAGGCCCA AGAAAAAAGA CAGCGATCAT GCCGCTCAGC ATGGCATGGA ATTGGGCGTG 1380AAAATCCCCA CCATTAACAC GGATTATTAT TCTTTCATGG GGGCTGAACT CAAATACAGA 1440AGGCTCTATA GCGTGTATCT CAATTATGTG TTTGCTTACT AG 1482(2) SEQ ID NO 327 information

Sequence properties:

(A) length: 810 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...810

(xi) sequence representation: SEQ ID NO 327: GTGCTAAACA CCACCCAAAA AAGCCTATTG GTTTTCATGG GGGTTTTTTT CCTTATCTTT 60GGCGTGGATC AAGCGATTAA ACACGCTATT TTAGAGGGGT TTCACTATGA AAGTTTGGTT 120ATAGATATTG TTTTAGTGTT CAATAAAGGC GTGGCGTTTT CCTTACTCAG TTTTTTAGAG 180GGGGGTTTGA AATACTTGCA AATCCTTTTA ATTTTAGGGC TTTTTATCTT TTTAATGCGC 240CAAAAGGAGC TTTTTAAAAG CCATGCGATA GAGTTTGGCA TGGTGTTTGG CGCTGGGGTT 300TCTAATGTTT TAAATCGGTT AGTATCATTG GGGCAATTGT ATATTCTTTA TGATGTATTG 360GCTATTAGAA GGGAAAAAAT GAAAAATAGC GCGCCTTTAA AGAATAAAGT TTTTTGTGGG 420TTATACGTTT TAAGTTTAAG CGCTTCTGTG CAAGCGTTTG ATTATAAAAT TGAAGTTTTG 480GCAGAGTCCT TTTCTAAAGT TGGCTTTAAT AAAAAAAAGA TTGACATAGC TAGGGGGATT 540TATCCTACAG AGACTTTTGT AACCGCTGTG GGTCAGGGCA ATATTTATGC GGATTTTTTA 600TCCAAAAGCC TTAAAGATCA AGGGCATGTT TTAGAGGGAA AAGTCGGCGG CACAATCGGT 660GGGATTGCTT ATGACAGCAC GAAATTCAAT CAAGGCGGAT CGGTTATATA TAATTATATC 720GGTTATTGGG ATGGCTATTT AGGGGGTACA AAGGCCTGCT TGATGGCACA AGTATCCATG 780ACTGCGCGCT TGGCTCTGAT GGCAAGGTGA 810(2) SEQ ID NO 328 information

Sequence properties:

(A) length: 597 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...597

(xi) sequence representation: 328 SEQ ID NO: ATGTTAGTTA CAAAACTTGC CCCCGATTTT AAAGCGCCTG CCGTTTTAGG AAACAATGAG 60GTTGATGAAC ACTTTGAGCT TTCTAAAAAT TTAGGCAAAA ATGGTGTGAT CCTTTTCTTT 120TGGCCAAAAG ATTTTACTTT TGTATGCCCT ACAGAAATCA TTGCGTTTGA CAAAAGAGTG 280AAAGACTTCC ACGAAAAAGG CTTTAATGTG ATTGGCGTGT CTATTGACAG CGAACAAGTG 240CATTTCGCAT GGAAAAACAC CCCTGTGGAA AAAGGCGGTA TCGGTCAAGT GTCTTTCCCT 300ATGGTGGCTG ATATCACTAA GAGCATTTCT AGAGACTATG ATGTGCTGTT TGAAGAAGCG 360ATCGCTTTGA GAGGTGCTTT TTTGATTGAT AAAAACATGA AAGTAAGACA CGCAGTGATC 420AATGACTTGC CATTAGGTAG GAATGCAGAT GAAATGCTTC GCATGGTAGA CGCTCTCTTA 480CACTTTGAAG AACATGGTGA AGTATGCCCA GCAGGTTGGA GAAAAGGCGA TAAAGGCATG 540AAAGCAACTC ACCAAGGCGT TGCAGAGTAT CTTAAAGAAA ATTCCATTAA GCTTTAA 597(2) SEQ ID NO:329 message

Sequence properties:

(A) length: 648 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) anorganism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...648

(xi) sequence representation: SEQ ID NO 329: ATGTTAAAAC TCGCCAGTAA AACGATTTGT TTGTCCCTAA TCAGCTCATT CACGGCTGTA 60GAAGCCTTTC AAAAACACCA AAAAGACGGC TTTTTCATAG AAGCCGGCTT TGAAACCGGG 120CTATTACAAG GCACACAAAC CCAAGAACAA ACCATAGCCA CCACTCAAGA AAAACCCAAA 180CCCAAACCCA AACCAAAACC CATTACCCCT CAAAGCACCT ATGGGAAATA CTACATCTCC 240CAAAGCACCA TTTTAAAGAA TGCGACTGAG TTGTTTGCAG AGGATAATAT CACCAACTTA 300ACCTTTTACT CTCAAAACCC TGTGTATGTA ACCGCTTATA ACCAAGAAAG CGCTGAAGAA 360GCTGGCTATG GTAATAACAG CTTGATTATG ATACAAAACT TCTTGCCTTA TAACTTGAAC 420AACATTGAGC TGAGTTACAC GGACGATCAA GGCAATGTGG TCAGTTTGGG CGTGATAGAG 480ACTATCCCTA AACAATCTCA AATCATTCTG CCCGCAAGCT TGTTTAACGA CCCACAGCTT 540AACGCCGATG GCTCCAACAA CTCCAAACCA ACACCACACG ATTTTCTGAT GCCAGCACGC 600AGAATCTGTT TAACAAGCTC AGCAAGGTTA CAACCAATCT TCAAATGA 648(2) information of SEQ ID NO 330

Sequence properties:

(A) length: 507 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...507

(xi) sequence representation: SEQ ID NO 330: ATGTTATCTT CTAATGATTT GTTTATGGTC GTTTTAGGGG CGATTTTATT GGTGTTGGTG 60TGCTTGGTGG GGTATTTGTA TCTTAAAGAA AAAGAGTTTT ACCATAAAAT GAGGCGTTTA 120GAAAAAACTT TAGATGAATC CTATCAAGAA AATTATCTCT ATTCTAAGCG TTTGAGAGAA 180TTAGAGGGGC GTTTGGAAGG CCTTTCTTTA GAAAAAAGCG CTAAAGAGGA CAGCTCATTA 240AAAACGACTC TTTCGCACCT TTATAACCAG TTGCAAGAAA TCCAAAAATC CATGGATAAA 300GAGCGCGATT ACTTAGAAGA AAAAATCATT ACTTTAGAAA ACAAATTTAA AGACATGGGG 360CATTATGCCG CTAGCGATGA AGTCAACGAA AAACAGGTTT TGAAAATGTA TCAAGAAGGC 420TATAGCGTGG ATTCTATTTC TAAAGAATTT AAAGTGAGTA AGGGCGAGGT GGAATTTATA 480TTGAACATGG CAGGGTTAAA ATGGTAG 507(2) SEQ ID NO 331 information

Sequence properties:

(A) length: 1017 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1017

(xi) sequence representation: SEQ ID NO 331: GTGGGTTTTG AATATTCCAT CAGTCATGCC GTTGAACACA ATAACCCTTT TTTGGATCAA 60GAACGCATCC AAGCGATTTC TAACGCTCGA GGCGAAGTCT GTGGACTCGA TCGAGTCAAA 120AATGAAATCA CAGACATGCC CAACACCTTT AACTACATCA ACAACGCTTT AAAAAACAAT 180GCTAAATTAA CCCCTACTGA AAAGCAAGCC GAAACCTACT ACCTGCAATC TACCCTTCAA 240AACATTGAAA AAATAGTCAT GCTTAGCGGG GGCGTTGCGT CTAACCCTAA ATTAGCCCAA 300GCGTTAGAAA AAATGCAAGA ACCCATTACT AACCCTTTAG AATTGGTAGA AAACTTAAAA 360AATTTAGAAT TACAATTCAG CCAATCTCAA AACAGCATGC TTTCTTCTTT GTCTTCTCAG 420ATCGCTCAAA TTTCAAATTC TTTGAACGCG CTTGATCCCA GCTCTTATTC TAAAAACGTT 480TCAAGCATGT ATGGGGTAGG TTTGAGCGTA GGGTATAAGC ATTTCTTTAC CAAGAAAAAA 540AATCAAGGGT TTCGTTATTA CTTATTCTAT GACTATGGTT ACACTAATTT TGGTTTTGTG 600GGTAATGGCT TTGATGGTTT AGGCAAAATG AATAACCACC TCTATGGGCT TGGCATAGAT 660TATCTTTTCA ATTTCATTGA TAATGCGCAA AAACATTCGA GCGTGGGGTT TTATGTAGGC 720TTTGCTTTAG CGGGGAGTTC GTGGGTAGGG AGTGGTTTAG GCATGTGGGT GAGTCAAATG 780GATTTCATCA ACAACTATTT GACGGATTAT CGGGCTAAAA TGCACACGAG TTTTTTCCAA 840ATCCCTTTGA ATTTTGGGGT TCGTGTGAAT GTGGATAGGC ACAATGGTTT TGAAATGGGC 900TTAAAGATCC CTTTAGCGGT CAATTCCTTT TATGAAACGC ATGGCAAGGG GTTAAACGCT 960TCCCTCTTTT TCAAACGCCT TGTCATGTTT AACGTGAGTT ATGTTTATAG TTTTTAG 1017(2) SEQ ID NO 332 info 332

Sequence properties:

(A) length: 243 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...243

(xi) sequence representation: SEQ ID NO 332: ATGATGTTTG AATTAACCAA AAAAACCAAA TTTGATGGCG AAATGATTGG CTACACAGAA 60GAACTTTTAA CCTTTTTAGT TAGAGATTTT TTTAATGGGA TTTTTAAATC CAAAGTAATA 120CCTAAAATGC CTATTTTTTG CGGTGATGTT AAATGCGAAG ATTTTAATGC CCTAAGAAGT 180TTAGTTTATC TTTCTGTGCT TGAGTTGGAA GAAACGATAA ATCCTAATAA AATCCCATTT 240TAA 243(2) SEQ ID NO 333 information

Sequence properties:

(A) length: 603 base pairs

(B)Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...603

(xi) sequence representation: SEQ ID NO 333: GTGCAATTAC TCAAAGACAA TAAAGAAGTG GTTGTTTTAG ATACAGATAG CCAAAAGTCT 60ATGGAAACTT TTGCTACAAT TCGTGCTGAA AAAGAACGCC CCACTTTTAG CTTATTTAAT 120CGTAGTAGTG GCTTTAGCGA TACTTTAAAG CAAATGGTAT CTAAGTATGA AAATATCCTT 180ATTGATACTA AGGGGGAATA CAGCAAAGAA ACCCAAAAAG CTATGCTTTT AAGTAATATT 240GTGCTAGTGC CAACAACTCC TAGCCAATTA GACACTGAAG TCTTAGCTAA TATGCTAGAA 300AGAATTGAGC AACTCCAAGA GCTTAATGAA AATCTAAGAG CCTTAATTGT CATCAATAGA 360ATGCCTACTA TTCCTACCCT TAAAGAAAGA CAAGCCTTAA TAGAGTTTAT TAAAGAAAAT 420AACCCTAGCG ATAGGATTAC ACTTTTAGAA AGCTCTTTGA GTGAGCGCAT TGTTTATAAG 480CGCAGTGTAA GCGAAGGCTT AGGGGTCATA GAATACAGCG ATAAAAAGGC TATCAATGAG 540TGGGTTAATT TTTATAACGA ATTAAAAAGC CATTTAGAAA AAGAGAAAAT ACATACGTTT 600TAG 603(2) SEQ ID NO 334 information

Sequence properties:

(A) length: 213 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...213

(xi) sequence representation: SEQ ID NO 334: ATGCGGTCGG ATGTTGAAGT TTTATCGCCT TTGCATAAAA TAGATGAAAA ATACCTTTTC 60CATTTAAAGA TTGCGGGGGA ATTGGCGAGC ATGGGTAAGA TTTTAAGTGT ATATTTAGCC 120CACAAGCACA GCGCGTATTT CATTTTAAAC GCTTTGAGTT ACGGCTTTAG CCACCAGGAT 180AGGGCGATCA TTTGCTTATT GGGCGCAATT TAG 213(2) SEQ ID NO 335 information

Sequence properties:

(A) length: 213 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...213

(xi) sequence representation: SEQ ID NO 335: ATGAGTGCGA TGATGCCAAG CCTTTTGACC TTGCAGTGGC TGAGTTTTAT CCTTTCTTTA 60GCCGAAAATT TGTGCCTGAC AGACAGCCAT CATTTAAAAT ACACGCTAGA AAAAAACAAG 120CTTGTGATCC ATTCTAATGA TGCGCTTTAC TTGGCTAAAG AAATGCTCCC CAAACTCATT 180AAGCCCATTC CTTTGACGAT AGAGTTTGCT TGA 213(2) SEQ ID NO 336 information

Sequence properties:

(A) length: 1437 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1437

(xi) sequence representation: 336: TTGAAGAAAA TCGCCCTTAT TTTAGATGGC ATTGTAGCAA AAAATTTTTT AGACTTGGTG 60CTAAGGCATT ATTCTAATCA TAATTTTTAT ATAGTGGTTG TCAAAGATGA GAGCCTTATC 120CCTAAAAATT ACCCGAGCAC TTTCGCTTTT CATTGTTTTG ATGCGACTTC CAGTTTTAGG 180CTTTTGCAGG TGTTAAATGA TGAGGTGAGC GATGCGTTTT TAATCATACA AGATTTTAAA 240GAGCAGCGCA TCATCCATAA AATCATTCAA ACCCATTTCA AACGCATGCG TGTGGTTTTG 300AGCGTGAAAA GAGATAGCGA AAAAACTTTA GAAAACAATG AAGAAAATAA AGATGAAAAG 360CTCATTTTGA TTGATGAATT TGAAGTTTTA GCCAATAAAT TCATTTCTCG TTTGCCTAAT 420ATCCCTAGCA CCCCTAGAGA GTTTGGGTTA GGCAAGGGCG AGATCATGGA GATTGATGTG 480CCTTTTGGGA GCATTTTTGC TTATAGGCAT ATTGGCTCTA TCAGGCAAAA AGAATACAGG 540ATTGTAGGGC TTTATCGCAA CGATGTTTTG TTGCTCTCCA CTAAATCTTT AGTCATCCAA 600CCACGAGACA TTCTTTTAGT GGCAGGCAAT CCGGAAATTT TAAACGCGGT GTACCATCAA 660GTCAAAAGCA ATGTGGGGCA GTTCCCAGCC CCCTTTGGTA AGAGCATTTA TTTATACATT 720GATATGCGAT TGCAGAGCCG AAAAGCGATG ATGCGCGATG TGTATCAAGC CTTGTTTTTG 780CACAAGCGTT TAAAGAGCTA CAAGCTCTAC ATTCAGGTTT TACACCCCAC TAGCCCTAAG 840TTTTATCATA AATTTTTATC GCTAGAAACC GAAAGCATTG AAGTGAATTT TGATTTTTAT 900GGGAAGAGTT TTATCCAAAA ACTCCATGAA GACCACCAAA AAAAAATGGG TTTGATTGTG 960GTAGGCAGAG AGCTTTTTTT CTTGAAAAAA CACCGAAGAG CCTTGCACAA AACAGCCACA 1020CCGGTTTATA AAACCAACAC CTCTGGCCTG TCTAAAACCA CTCAAAGCAT TGTGGTTTTG 1080AATGAAAGTT TAAGCATTAA TGAAGACATG TCTTCAGTGA TTTTTGATGT GTCTATGCAA 1140ATGGATTTGG GCTTGTTGCT TTATGATTTT GACCCTAACA AGCACTATAA AAACGAGATT 1200GTCAATCATT ACGAAAATTT AGCCAACACC TTTAACCGCA AGATTGAGAT TTTTCAAACC 1260GATATTAAAA ACCCTATCAT GTATCTCAAT TCTTTAAGAA ATCCCATTTT GCATTTCATG 1320CCTTTTGAAG AGTGCATCAC GCAAACGCGC TATTTGTGGT TTTTATCCAC TAAAGTGGAA 1380AAATTAGCGT TTTTGAACGA TGATCACCCT CAAATTTTTA TCCCTGTAGC GGAGTGA 1437(2) SEQ ID NO 337 information

Sequence properties:

(A) length: 1257 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1257

(xi) sequence representation: 337 ID NO: ATGAAAAAAG TCTATTTTAA AACTTTTGGG TGTAGGACGA ATCTTTTTGA CACGCAAGTG 60ATGGGCGAAA ATTTAAAGGA TTTTAGCGCG ACTTTAGAAG AACAAGAAGC CGATATTATT 120ATTATCAATT CTTGCACCGT AACCAATGGG ACCGATAGCG CGGTAAGGAG TTACGCTAGA 180AAAATGGCAC GATTGGATAA AGAAGTGCTA TTTACTGGTT GCGGGGTGAA AACCCAAGGC 240AAAGAGCTTT TTGAAAAAGG GCTTTTAAAG GGCGTTTTTG GGCATGACAA TAAAGAAAAG 300ATTAACGCGC TTTTACAAGA AAAAAAGCGT TTTTTCATAG ATGACAATTT AGAAAACAAA 360CATTTAGACA CCACGATGGT GAGCGAGTTT GTGGGAAAAA CCAGGGCGTT TATCAAGATC 420CAAGAGGGCT GTGATTTTGA TTGCAATTAT TGCATTATCC CAAGCGTGAG AGGGAGGGCT 480AGGAGTTTTG AAGAGAGGAA AATTTTAGAG CAAGTGGGCC TTTTATGCTC TAAAGGGGTT 540CAAGAAGTGG TTTTAACCGG CACTAACGTG GGGAGCTATG GGAAAGATAG AGGAAGCAAT 600ATCGCGCGAT TGATTAAAAA ATTAAGCCAG ATTACTGGAT TGAAACGCAT TAGGATTGGG 660AGTTTAGAGC CTAATCAAAT CAACGATGAA TTTTTAGAGC TTTTAGAAGA GGATTTTTTA 720GAAAAACATT TGCATATCGC TTTACAGCAC AGCCATGATT TCATGCTAGA GAGAATGAAT 780CGAAGAAACC GCACTAAAAG CGATAGGGAA TTATTAGAGA TAATCGCTTC TAAGAATTTT 840GCTATCGGCA CGGATTTTAT TGTGGGGCAT CCGGGCGAGA GTGAAAGCGT TTTTGAAAAG 900GCGTTTAAAA ATTTAGAAAG CTTGCCTTTA ACGCATATCC ACCCTTTTAT TTACAGCAAG 960CGAAAAGACA CCCCCTCTAG TTTGATGCGT GATAGCGTGA GTTTGGAAGA TTCTAAAAAG 1020CGTTTGAATG CGATTAAAGA TTTGATTTTT CATAAAAATA AGGCGTTCAG GCAATTGCAA 1080CTCAAACTCA ACACGCCCCT AAAAGCCCTA GTGGAAGCGC AAAAAGACGG CGAATTTAAA 1140GCCTTAGATC AATTTTTCAA CCCCATTAAA ATCAAAAGCG ATAAGCCTTT AAGGGCTAGT 1200TTTTTAGAAA TCAAAGAGTA TGAAATTAAG GAGAGGGAAA ATCATGCCGT TTTCTAA 1257(2) SEQ ID NO 338 information

Sequence properties:

(A) length: 528 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...528

(xi) sequence representation: SEQ ID NO 338: TTGAAAATCG CTTACAGGCT TTTAGGTTTG ATGAGCTTTA TCGCGCTTGT CTTAGCGATC 60GTTTTAATCA GTATCCTGCC CTTACAAAAA ACCGAACACC ATTTCGTGGA TTTTTTAAAC 120CAGGACAAGC ATTACGCCAT TATCCAAAGA GCGGATAAAA GCATTTCCAG TAATGAAGCG 180TTGGCTCGTT CGCTCATTGG GGCGTATGTG TTAAACCGAG AGAGCATTAA TCGCATTGAC 240GATAAATCCC GCTATGAACT GGTGCGCTTG CAAAGCAGCT CTAAAGTGTG GCAACGCTTT 300GAAGATTTGA TTAAAGCCCA AAACAGCATC TATGTGCAAA GCCATTTAGA AAGAGAAGTC 360CATATCGTCA ATATTGCGAT CTATCAGCAA GACAATAACC CCATTGCGAG CGTGTCCATT 420GCGGCTAAAC TTTTGAATGA AAACAAGCTC GTGTATGAAA AGCGTTATAA AATCGTATTG 480AGCTATTTGT TTGACACCCC GGATTTTGAT TACGCTTCCA TGCCCTAA 528(2) SEQ ID NO 339 information

Sequence properties:

(A) length: 561 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...561

(xi) sequence representation: SEQ ID NO 339: TTGTTGCTTG TTTCTCGCTT TTTAAACGCC ATTGATCCTT TTAATTTAGG GGTGTTGTTG 60AGCCGTTTCC AAATTAAAAA TGGTTGTATT TATGGGGTGT GTTCTTACAA GGTTTCAAAA 120TTTACCCCTG GATATGAAGA AAGCAAAGCG CGAGTTTTAA ACGCTCTCAA TATTTTAAGC 180AAGCATCAAA TTTGGCAATC CAATCAAGAA AGCGTTACAA AAGTCAAAGG AACTTTTGTT 240TTCATTTTAG AAAATGACCT GCATTTAGAC GAAAACTCTT TTTATAAGAA ACTTTTAAAT 300CTGATTATAG ACAATGACTT TTTTAACCGC TCTCATTTAG TAACTCCGAG CAATGGCACC 360AACTCCCACC CTGAATTGCA CCGCTCTATC ACGCCCAGAG AAGCCGCTAG GATACAAAGT 420TTTAGCGATG ATTATATCTT TTATGGCAAT AAAACGAGCG TTTGCAAGCA AATCGGTAAC 480GCCGTGCCTC CTCTTCTAGC CCTAGCCTTA GGCAAAGCGA TCTTAAAAAG CGCAAGAAAT 540GATACAAATC CATCACGCTA A561 (2) information SEQ ID NO:340

Sequence properties:

(A) length: 522 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...522

(xi) sequence representation: SEQ ID NO 340: ATGGGGTTAA AGAATAAAAT CAAGGGTTTT GTTAAAGAGA GAATGCCTTT TGTAATGAGA 60TGCGTTCGTG GTTTAAAAGG GGCCAAAGAC ACCCATGAAA ACGCCCATGA TAGGGACGCT 120TATTGTGGAA TCAATCGTGA AATTAAGGAA ATGCTAGAGG CTAAAAAACT TCATTTTCTT 180CAAGAAAAAG CTTTATTCAA CCACGACCAT CAAGAAAGCG TGTTTTTAGC TATCGCCTCT 240TTAAATAATG AAAGTTTCAT TGAATACAAC AAGAGTATTT ATAAAAATAG TTCTCTTAAT 300TATAATTATG GGGGGCATTT AGAAGATAGG GTCATCCATC CCACTTTAAC TTTACCCAAT 360CCCACGCATT CGGGTTATTT TGACTATGAT AAAAAAAGTC AAAACCCTAA AAGCCCTCTA 420AACCCATGGG CTTTTATTAG AGTCAAAAAC GAAATCGTTA CTTTAGAAGA GAGTTTGTTT 480TCTATGCTTC CTGCCGTTCA AAGGGGGGGT CATTGGTTTT AA 522(2) SEQ ID NO 341 information

Sequence properties:

(A) length: 528 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...528

(xi) sequence representation: SEQ ID NO 341: TTGTGGCACC AACTCTATCA TTACTGTAAT TATACGCTTT CTTTTATCCC TAAAAATGAG 60TGGGTAGTAA AAATTGATTG CGATCATATC TATGACGCTA AAAAGCTTTA TAAAAGTTTT 120TATATTCCTA AGAATATTAA AGAGGTTGTG ATGTATTCGC GCATTAATTT TGTGGTGCGA 180GATTTTGAAG TGTTTGTTCG TAACGATGGG GATTTTGGGT TTTTAGACGC ATGGGGGGAT 240CATTGGTTAT TGTATAACGA TTGCGAGCCT TTTGAAATTT GGCGCTACAA TGATGAAAGT 300TATGAAGTCC TAAAGCTTAA AGATAAACAC CATATTAAAG ATAAGGAAAT GGTGCAATGG 360CACTTCCCTT TGGCTAAAAA GAGGCGAAAC GCTATTGTTT ATGACGATTT GATCCCTTTA 420GAAGAATTCA AAAAACGCCA TGCCGATTTG ATAGGCACAA GGATTGAAGA AAGCATGCTA 480GATGAAAAGA GGATTTTAGA GGTATATCAA AAATTCCGCT TGCCTTAA 528(2) SEQ ID NO 342 information

Sequence properties:

(A) length: 1074 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1074

(xi) sequence representation: SEQ ID NO 342: ATGCAAAAAC CACAAAATAA ACCCAGCTCA TCGCAACAAT CTCCTCAAAA CTTTTCTTAC 60CCAGAGTCCA AACTAGGCTC TAAAAACTCT AAAAACAGCC TTTTACAGCC TTTAGTAACT 120CCTAGCAAAG TAAGCCCCAC TAACGAAGTT AAAACGCCAA CAAACGACGC TAATCCCCCT 180TTAAAGCATT CTTCACAAGA TCAAGAAAAC AACCTCTTTG TAGCGCCACC CACTGAAAAA 240ACGCTCCCTA ACAACACCTC TAGTGCTGAT GCGAGTGAAA ACAATGAAAG CAACGAAAAT 300AGGGATAATG TGGAAAAACA AGCGATTAGA GATCCTAATA TCAAAGAATT CGCATGCGGG 360AAGTGGGTTT ATGATGATGA AAATTTACAA GCCTATCGCC CAAGCATTTT AAAACGCGTT 420GATAAAGACA AAGAGATTAC AACAGACATT ACCCCTTGCG ATTACAGCAC CGCTGAAAAT 480AAAAGCGGTA AAATCATTAC CCCCTATACT AAAATCTCTG TTCATAAAAC AGAGCCTTTA 540GAAGACCCTC AAACTTTTGA AGCTAAAAAT AATTTCGCCA TTCTCCAAGC CAGAAGCTCT 600ACAGAAAAGT GTAAAAGGGC TAGAGCGAGA AAAGACGGCA CGACCAGGCA ATGCTATCTG 660ATAGAAGAGC CTTTAAAACA AGCGTGGGAG AGCGAGTATG AAATCACCAC GCAATTAGTG 720AAAGCCATAT ATGAACGCCC CAAACAAGAC GATCAAGTAG AGCCGACTTT TTATGAAACC 780AGCGAATTGG CTTATTCTTC CACACGAAAA AGCGAAATAA CGCGTAATGA ATTGAATTTG 840AATGAAAAAT TCATGGAATT TGTGGAAGTG TATGAGGGGC ATTATTTAAA CGATATAATC 900AAAGAGAGCA GCGAATACAA AGAATGGGTT AAAAACCATG TGCGCTTTAA AGAAGGGGTG 960TGCATGGCCT TAGAAATAGA AGAGCAACCA CGAGCCAAAA GCACGCCTTT GAGTATTGAA 1020AACTCTCGTG TTGTGTGTGT CAAAAAGGGG AATTATTTAT TCAATGAAGT TTAA 1074(2) SEQ ID NO 343 information

Sequence properties:

(A) length: 432 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...432

(xi) sequence representation: SEQ ID NO 343: ATACAATACC CCAAGTCATC TTTTTTTCAA AAAAGGGGTA GGAATGGCAA CCATTCAACC 60ATTCAACCAT TCAACCATTC AACCATTCAA CCATTCAACC ATTCAATCAT TCAATCATTC 120AATCATTCAA TCATTCAATC ATTCAATCAT TCAATCATTC AATCATTCAA TCATTCAACC 180ATTCAAGCAA CGCTACCTTA TTTTTATAAC TATTTATCTT TTTACAAAAA CCTATTTAAA 240AATCCCCTAT TTTTTATTAT TCCCCCTTTT ATTAACCCTT TTATTAACCC TTTTATTAAC 300CCTTTTATTA ACCCTTTTAT TAACCCTTTT ATTAACCCTT TTATTAACCC TTTTATTAAC 360CCTTTTATTA ACCCTTTTAT TAACCCTTTT ATTAACCCTT TTATTAACCC TTTTATTAAC 420CCTTTCATAT AA 432(2) SEQ ID NO 344 information

Sequence properties:

(A) length: 729 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...729

(xi) sequence representation: SEQ ID NO 344: TTGAAAGTCA ATTTCTTTGC CACTTGTCTA GGAGCAGCTA TTTATAGCAA CGCATCGCTT 60AACGCTATCA AATTACTCCG CAAGGAAAAT TTGGAAGTGG TTTTTAAAAA AGACCAGACA 120TGTTGTGGCC AGCCAAGCTA CAACTCAGGA TACTATGAAG AGACTAAAAA AGTCGTTTTA 180TACAATATCA AACTTTATTC CAATAACGAC TACCCTATTA TTTTGCCTAG CGGTTCATGC 240ACAGGGATGA TGCGGCATGA TTATTTGGAA TTGTTTGAAG GGCATGCGGA ATTTAACATG 300GTTAAAGATT TTTGCTCTAG GGTGTATGAA TTGAGCGAGT TTTTGGATAA AAAATTGCAA 360GTCAAATACG AAGATAAGGG CGAACCTCTC AAAATCACAT GGCATTCTAA TTGCCATGCC 420TTAAGGGTGG CTAAAGTGAT TGACTCGGCG AAAAATCTCA TCAGACAGCT TAAAAATGTG 480GAACTCATTG AATTGGAAAA AGAAGAAGAA TGCTGCGGGT TTGGGGGGAC TTTTTCAGTT 540AAAGAGCCTG AAATTTCAGC GGTTATGGTC AAAGAAAAGA TTAAAGACAT AGAGAGCCGT 600CATGTGGATG TGATCGTTTC AGCGGATGCT GGGTGCTTGA TGAATATCAG CACCGCTATG 660CAAAAAATGG GCTCTTTGAC AAAACCCATG CATTTTTATG ACTTTTTAGC CTCAAGGCTT 720GGACTTTAA 729(2) SEQ ID NO 345 information

Sequence properties:

(A) length: 1206 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1206

(xi) sequence representation: SEQ ID NO:345: ATGATTTTTG GGGATTTTAA ATATCAAAAA AGCGTTAAAA AACTCACAGC CACTAACCTT 60AACGAGCTTA AAAACGCCCT GGATTTTATC TCTCAAAATA GGGGGAAGGG GTATTTTGTG 120GGGTATCTTT TGTATGAAGC GCGCTTAGCG TTTTTAGATG AAAATTTTCA AAGCCAAACC 180CCTTTTTTGT ATTTTGAACA ATTTTTAGAA AGAAAAAAAT ACCCTTTAGA GCCTTTAAAA 240GAGCATGCGT TTTACCCTAA AATCCACAGC TCTTTAGATC AAAAAACTTA TTTCAAGCAG 300TTTAAGGCCG TTAAAGAGCA TCTCAAAAAC GGCGATACCT ATCAAGTGAA TTTGACAATG 360GATTTATTGT TAAACACTAA AGCCAAACCA AAGCGCGTTT TTAAGGAAGT GATACACAAC 420CAAAACACGC CTTTTAAGGC TTTTATAGAA AATGAGTTTG GGAGCGTTTT AAGCTTTTCG 480CCGGAATTGT TTTTTGAATT AGAGTTTTTA GACACAGCGA TTAAGATTAT CACAAAACCC 540ATGAAAGGCA CGATCGCTCG CTCAAACAAC CCCTTGATAG ATGAAAAAAA CCGATTGTTT 600TTGCAAAATG ATGACAAAAA TAGAAGCGAA AATGTGATGA TCGTGGATTT ATTGCGTAAC 660GATTTGAGCC GCTTGGCCTT AAAAAATAGC GTGAAAGTCA ATCAATTGTT TGAAATCATC 720AGTTTGCCGA GCGTGTATCA AATGATAAGC GAGATTGAAG CTCAATTGCC CCTAAAAACA 780AGCTTGTTTG AGATTTTTAA GGCGTTGTTC CCTTGCGGCT CTGTGACCGG ATGCCCTAAA 840ATCAAAACCATGCAAATCAT TGAAAGTTTA GAAAAACGCC CTAGGGGGGT GTATTGTGGG 900GCGATAGGCA TGGTTGGAGG AAAAAAAGCC CTTTTTAGCG TGCCTATCCG CACTTTAGAA 960AAAAGAGCGC ATGAAGATTT TTTGCATTTA GGGGTAGGGA GTGGGGTAAC TTATAAAAGT 1020AAAGCTTCAA AGGAATATGA AGAGAGCTTT TTAAAATCCT TTTTTGTGAT GCCCAAAATA 1080GAATTTGAGA TCGTGGAAAC GATGAGAGTT ATCAAAAGGG ATCAAAAATT AGAGATTAAC 1140AATAAAAACG CCCATAAAGA ACGCTTAATG CATAGCGCCC AATATTTTAA CTTTAAATAC 1200AGATGA 1206(2) SEQ ID NO:346 information.

Sequence properties:

(A) length: 795 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...795

(xi) sequence representation: SEQ ID NO 346: ATGAAAATCA GTGTTAGTAA AAACGATTTA GAAAACACTT TGCGCTACTT GCAAGCTTTT 60TTGGATAAAA AGGACGCTTC CTCTATCGCT TCACACATCC ATTTAGAAGT CATTAAAGAA 120AAGCTCTTTT TAAAAGCCAG CGATTCAGAT ATTGGACTAA AAAGCTATAT TTCTACGCAA 180TCTACCGATA AAGAGGGCGT AGGCACGATC AACGGGAAGA AGTTTTTAGA TATTATCTCA 240TGTTTGAAAG ACTCTAATAT TGTTTTAGAG ACTAAAGATG ACAGCTTGGT GATCAAACAA 300AATAAAAGCT CTTTCAAACT CCCCATGTTT GACGCTGATG AGTTCCCTGA ATTCCCTGTT 360ATTGATCCAA AAGTGAGTTT AGAAATCAAT GCCCCCTTTT TGGTGGATGC GTTTAAAAAG 420ATCGCTCCTG TGATTGAGCA AACTAGCCAT AAAAGGGAAT TAGCCGGTGT TTTAATGCAA 480TTCAATCAAA AACACCAAAC CCTTTCAGTG GTAGGCACGG ATACCAAGCG GCTCTCTTAC 540ACGCAGTTAG AAAAAATCTC TATCCATTCC ACCGAAGAAGACATCTCTTG CATTTTGCCT 600AAAAGGGCTT TATTGGAAAT CCTTAAACTT TTTTATGAAA ATTTCAGTTT TAAAAGCGAC 660GGCATGTTAG CGGTGGTTGA AAACGAAACG CACGCTTTTT TCACCAAGCT CATTGATGGG 720AATTACCCTG ATTATCAAAA AATCCTCCCT AAAGAATACA CTTCTTCTTT CACTTTAGGC 780AAGGAAGAAT TTTAA 795(2) SEQ ID NO 347 information

Sequence properties:

(A) length: 939 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...939

(xi) sequence representation: SEQ ID NO:347: TTGAATAATT TAGAGCCTTT GGGCGCGGAA GTGTTTGTGG GGTTAGACGG CATTGATGCG 60ATGATAGAGG AGTGCGTTTC CAATTTAGTC ATTAACGCCA TTGTGGGCGT AGCCGGATTG 120AAAGCGAGCT TTAAAAGCTT ACAAAGGAAC AAAAAACTAG CCCTAGCGAA TAAAGAAAGT 180TTAGTGAGCG CGGGGCATTT ATTAGACATT TCACAAATCA CGCCCGTTGA TAGCGAGCAT 240TTTGGTTTGT GGGCGTTGTT GCAAAACAAG ACTTTAAAGC CTAAATCTTT AATCATTAGC 300GCGAGTGGGG GGGCTTTTAG GGACACGCCC TTAGATCTTA TCGCTATTCA AAATGCGCAA 360AACGCGCTCA AGCACCCTAA TTGGAGCATG GGGGATAAAA TCACCATTGA TTCAGCGAGC 420ATGGTCAATA AACTTTTTGA AATTTTAGAA ACCTATTGGC TTTTTGGTGC GTCTTTAAAG 480ATTGACGCGC TGATTGAAAG AAGTTCTATC GTGCATGCTT TGGTGGAGTT TGAAGACAAC 540TCTGTCATTG CGCATTTAGC GAGTGCGGAC ATGCAATTAC CCATAAGCTA TGCCATTAAC 600CCTAAATTAG CTTCTTTGAG TGCTTCCATT AAACCCTTAG ATTTATACGC TTTAAGCGCG 660ATTAAATTCG AACCCATTAG CGTGGAGCGC TACACTTTGT GGCGTTATAA AGATTTGTTG 720TTGGAAAACCCAAAGCTTGG CGTGGTGCTG AATGCGAGCA ATGAAGTGGC GATGAAGAAG 780TTCTTGAATC AAGAAATCGC TTTTGGTGGC TTTATCCAAA TCATCTCTCA AGCTTTAGAA 840TTGTATGCTA AAAAATCTTT CAAGCTCTCT AGTTTAGATG AAGTGCTAGC GTTAGATAAG 900GAAGTTAGGG AGCGTTTTGG AAGTGTAGCG AGAGTGTAG 939(2) SEQ ID NO:348 information

Sequence properties:

(A) length: 873 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...873

(xi) sequence representation: SEQ ID NO:348: ATGTTAGAAA ATGTCAAAAA ATCCCTTTTT AGGGTTTTGT GCTTGGGCGC GTTGTGTTTA 60GGGGGGCTAA TGGCAGAGCA AGACCCTAAA GAGCTTGTCG GTTTGGGGGC AAAGAGCTAC 120AAAGAGCAGG ATTTCACTCA GGCTAAGAAA TATTTTGAAA AAGCTTGCGA TTTGAAAGAA 180AATAGCGGGT GTTTTAATTT AGGGGTGCTT TATTATCAAG GGCATGGGGT GGAAAAGAAT 240TTGAAAAAAG CCGCTTCATT TTACTCTAAA GCTTGCGATT TAAATTACAG CAATGGGTGT 300CATTTGCTAG GGAATTTATA TTATAGCGGG CAAGGCGTGT CCCAAAACAC CAACAAAGCC 360TTGCAATACT ACTCTAAAGC GTGCGATTTG AAATACGCTG AAGGGTGTGC GAGCTTAGGG 420GGGATCTATC ATGATGGCAA AGTGGTTACT AGGGATTTTA AAAAAGCGGT GGAATATTTC 480ACTAAAGCTT GCGATTTGAA CGATGGCGAT GGTTGCACGA TATTAGGGAG CTTGTATGAT 540GCAGGCAGAG GCACGCCTAA AGATTTGAAA AAAGCGCTCG CTTCGTATGA TAAAGCTTGC 600GACTTAAAAG ACAGCCCAGG GTGCTTTAAC GCAGGGAACA TGTATCATCA TGGCGAAGGT 660GCGGCGAAGA ATTTTAAAGA GGCCCTCGCT CGTTATTCTA AGGCATGCGA GTTGGAAAAT 720GGCGGAGGGT GTTTCAATTTAGGGGCTATG CAATACAATG GCGAAGGCGC AACAAGGAAT 780GAAAAGCAAG CCATAGAAAA CTTTAAAAAA GGCTGTAAAT TAGGCGCTAA AGGGGCATGC 840GATATTCTCA AGCAGCTCAA AATCAAAGTT TAG 873(2) SEQ ID NO:349 information

Sequence properties:

(A) length: 714 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...714

(xi) sequence representation: SEQ ID NO 349: ATGAAGTCAA ATAAAAAGTC CAATCATTTA AGAGCGATTT ATAGGGCTTT AGTGATCGCT 60ATAGGCTTAG CCGTTATCAT TGTTTTCAAT TATTTTAACC GCAAAAACAA TAACGCCCGC 120TCCAGCCGTA GGGCTTGTTC GTGTTTTTTT TCTCTCACCG GGGTTAATTT AGAAAAAATA 180GGTTCCTTTG ACACGGGCGC TAAACTCATT GTCTTAAACC ACCAAAGCTT ACTAGACATT 240ATTTATTTAG AAGCCTACCA CCCTAGTAAT ATTTGCTGGA TCGCTAAAAA AGAGCTGGGC 300GAAATCCCTT TTTATGGGCA TGCTCTAACG GATACCGGAA TGATCTTAAT TGACAGAGAG 360GATAAAAAGG GGATAGTGAG CCTTTTGAAA GCATGTAAAG AAAAGCTAGA TCAAAACCGC 420CCTTTAGTGA TTTTTCCTGA AGGCACTAGA GGCAAAGGAG GAGAAAAATT CCTCCCCTTT 480AAGCAAGGGG CTAAAATCAT CGCTGAAAAA TTCCAGCTCA AAATCCAGCC CATGGTGTTA 540ATCAATTCCA TTAAAATCTT TAATTCCAAG CCCCTAGAAG CTTATAAAGC GCGCACCCGT 600TTGGTCATGC TAGAAAGCTA TACGCCTGAT TTTAGCTCGC CCACCTGGTA TGAAGAATTA 660CAAGAACGCA TGCAAAAAGA ATATTTAAAA CACTACCACG AACTAAACGC ATGA 714(2) SEQ ID NO 350 information

Sequence properties:

(A) length: 2046base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2046

(xi) sequence representation: SEQ ID NO 350: ATGGGTTTTG AAAAAAGCAT TTTAGACAAT TTGAACGGAG CGCAAAAAAT TGCCGCATGC 60CACATTCAAG GGCCTTTATT GATTTTAGCG GGAGCTGGGA GCGGTAAGAC TAAGACTTTA 120ACGAGCCGTT TAGCGTATTT GATTGGCGCT TGTGGCGTGC CTAGCGAAAA CACTTTAACG 180CTCACTTTCA CCAATAAAGC GAGTAAAGAA ATGCAAGAAA GGGCTTTGAA ATTGTTGAAA 240AACCAAGCCC TTATCCCCCC CTTGCTTTGC ACTTTCCATC GTTTTGGTTT GCTGTTTTTA 300AGGCAACACA TGAATCTTTT AAAAAGGGCG TGCGATTTTT CGGTGCTAGA TAGCGATGAA 360GTGAAAACGC TCTGCAAACA GCTCAAAATT TCAAATTTCA GGGCGAGCAT TTCTCAAATC 420AAAAACGGCA TGATGGATTT GAGCGTGCAA GATAGCGAAT GTTACAAAGC GTATGAGCTT 480TATCAAAACG CGCTCAAAAA AGACAATTTA GTGGATTTTG ACGATTTGCT TTGTTTGAGC 540CTTAAGATTT TACAAGATAA TGAAAAACTC GCCAAAGAGA CCAGCGAACG CTACCATTAC 600ATTATGGTAG ATGAGTATCA AGACACGAAC GCCCTGCAAC TGGAATTTTT AAAACAATTG 660AGTTTCACGC ACCATAATTT GTGCGTGGTG GGCGATGACG ATCAGAGCAT TTATGGGTTT 720AGGGGGGCTG ATATTTCTAA CATTTTAAAT TTTTCCAAGC ATTTTAAAGG GGCTAAAATA 780GTGAAATTAG AGACCAACTA CCGCTCTAGC GCTGAAATCT TAGCGTGCGC TAATTCCCTG 840ATCAGCCATA ACCAACACCG CCACATTAAA ACGCTTCAAA GTTTCAAAGG TTCGCACAAA 900AGCGTGATTT GTAAAGAATA CCCCACGCAA AAAGAAGAGA GCCTGGATGT GGCTTATCAG 960ATCAAAGCCC TTTTAAAGAA GGGCGAGAAT TTAGAAAATA TCGCTATTTT GTATCGTTTA 1020AATGGGCTTA GCCGCAGCAT TGAAGAGAGC TTGAACGCTT TGAATATCCC TTATAGGCTC 1080ATTGGTGCGG TGAGTTTCTA TGAAAGAGCC GAGGTTAAAG ACGCTTTGGC ACTCATGCAT 1140GTGGTGGCGA AAAAAGACGA TCGCTTTTTT ATTAAACGCG TTTTAAACAA GCCCCCAAGA 1200GGCCTTGGCA AGATCACTCA AGAATGGATT TTTTCTCTTT TAGATGAAGA GGGTTTGAAT 1260TTAGAAGAAG CGCTAAAAAT TGGGGCGTTT AAAGACAAAC TCAACCCTAA AAACGAATAC 1320GCTTTAAAGA AATTCACCGC TATGATAGGG CGTTTGAGGG AGGCTTTTGA AATTTCAGTA 1380GAGAAGTTTT GCGAGCGGTT TTTAGAAGAG ACTAACCTTT TAAAAAGCTA TGAAAAAGAA 1440GACAATTACG AAGAAAGAGA GGGCTTTGTT AAAGAGCTTT TAAGTTTAGT GAAAGAGCAT 1500TTTAAAACTA ACCCCACGCA TTCTTTACTG GATTTTTTGA ATGAAAGCGC ACTGGATGTC 1560CATAATACAG AAAACGCGCA AAAAGTGAGT TGCATGAGCG TGCATATGAG TAAGGGCTTA 1620GAGTTTAAGC ATGTGTTTGT GATCGGGTTA GAAGAGGGGT TTTTCCCGCA TAGGGGGTTC 1680AATCAAGAAA GCGATTTGGA AGAAGAAAGG CGCTTGGCTT ACGTGGCGAT CACTAGGGCT 1740AAAGAAGAAT TACAACTTTC TTATGTCAAA GAGCGTTCGT ATTTTGGGAG GAAAATTTCT 1800TGCTCGCCCT CTGTGTTTTT AGAAGAAGCC CAGTTGCTCC AACAAGACAA GCCTCCTAAA 1860CAAAATCACC AAAAAGATAC GCCCATTAAA GTGGGGGATT TGATCAAACA TAAGATTTTT 1920GGCACCGGGA GGGTTTTAGG CGTAGAAAAA GGCTTGAGCG GTTTGTGCTT GAAAATCAAT 1980TGCGGAGGGA ATGTCTATGA TAAAATTTCA GAAAAATTTG TAGAAAAAGT GGATAACGAG 2040TTTTGA 2046(2) SEQ ID NO 351 information

Sequence properties:

(A) length: 831 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...831

(xi) sequence representation: SEQ ID NO 351: ATGAAAACTT CTAACACAAA AACCCCTAAA CCCGTTTTAA TCGCCGGGCC ATGCGTCATT 60GAGAGTTTAG AAAATCTAAG AAGTATCGCT ATTAAATTAC AACCCCTAGC CAACAACGAG 120CGGTTGGATT TTTATTTTAA AGCGAGTTTT GATAAGGCTA ACCGCACGAG TTTGGAGAGT 180TACAGAGGAC CTGGTTTAGA AAAAGGCTTA GAAATGTTAC AAACTATCAA AGATGAATTT 240GGTTATAAAA TTTTAACCGA TGTGCATGAG AGCTATCAAG CAAGCGTGGC AGCCAAGGTA 300GCGGATATTT TACAAATCCC GGCGTTTTTG TGCCGCCAAA CGGATCTGAT TGTAGAAGTG 360AGCCAAACTA ACGCCATTGT CAATATCAAA AAAGGGCAAT TCATGAACCC AAAAGACATG 420CAATATTCCG TTCTAAAAGC CCTTAAAACA AGGGATAGTA GCATTCAAAG CCCCACTTAT 480GAAACAGCGT TAAAAAATGG CGTGTGGCTG TGTGAAAGGG GGAGCAGCTT TGGGTATGGG 540AATTTAGTGG TGGATATGCG CTCTTTAAAA ATCATGCGAG AATTTGCCCC TGTGATTTTT 600GACGCTACCC ATAGCGTGCA AATGCCAGGG GGAGCGAACG GGAAAAGTTC AGGAGACAGC 660TCTTTTCCCC CTATTTTACC CAGAGCGGCG GCGGCGGTGG GGATTGATGG GCTGTTCGCT 720GAAACGCATA TTGATCCTAA AAACGCCCTA AGCGATGGAG CAAACATGCT AAAACCTGAC 780GAGCTAGAAC ACTTAGTAAC CGACATGTTA AAAATCCAAA ATTTATTTTA A831 (2) SEQ ID NO 352 information

Sequence properties:

(A) length: 1311 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1311

(xi) sequence representation: 352: ATGATGAAAT TTTTTCTTTT AAAGAAATTC AGCGAATTTT TAAACACTCA AACGCATTTT 60AACCTCAAAC GCTTGAACGC GTCTAGTTTT TTATTAGAGA CTTTTTCTAA AGAAAAACAC 120GCCTTTGTTG TGGATTTGAG CGCGCCTTAT ATTGGTTTGT CCAAAAAACC CCCAGAGAGC 180GTTTTAAAAA ACACTTTAGC GTTAGATTTT TGTTTGAATA AATTCACCAA AAACGCCAAA 240ATTTTACAAG CAAACGTCAT TGATAACGAT CGGATTTTAG AAATCAAGGG CGCTAAAGAT 300TTAGCTTATA AGAGTGAAAC TTTTATTTTG CGTTTAGAAA TGATCCCTAA AAAAGCCAAT 360CTCATGATTT TAGATCAAGA AAAATGCGTG ATAGAGGCTT TTCGTTTTAA TGACAGGGTG 420GCTAAAAACG ATATTTTAGG GGCATTGCCT CCTAATATTT ACGAGCATCA AGAAGAGGAT 480TTGGATTTTA AGGGATTGTT GGACATTTTA GAAAAAGATT TTTTATCCTA TCAGCACAAA 540GAATTGGAAC ACAAAAAAAA TCAAATCATC AAGCGATTAA ACGCCCAAAA AGAACGCTTG 600AAAGAAAAAT TAGAAAAACT AGAAGATCCT AAAACTTTAC AGCTGGAAGC GAAAGAATTG 660CAAACTCAAG CCTCATTGTT GCTCACTTAC CAGCATTTAA TCAACAGGCG TGAAAATCGC 720GTGATTTTAA AGGATTTTGA AGATAAAGAA TGCATGATTG AAATTGATAA GAGCATGCCC 780TTAAACGCTT TTATCAATAA AAAATTCACT CTCAGCAAGA AAAAGAAACA AAAATCGCAA 840TTCTTGTATT TAGAAGAAGA GAATCTGAAA GAAAAAATCG CTTTTAAGGA AAATCAAATC 900AACTATGTTA GAGACGCTGC AGAAGAAAGC GTTTTAGAAA TGTTTATGCC GGTAAAAAAC 960TCTAAAATCA AACGCCCGAT GAACGGGTAT GAAGTGCTGT ATTATAAGGA TTTTAAAATC 1020GGTTTAGGGA AAAACCAAAA AGAGAATATC AAGCTTTTAC AAGACGCAAG AGCGAATGAT 1080TTGTGGATGC ATGTGAGAGA TATTCCTGGA TCGCATTTGA TCGTTTTTTG CCAAAAGAAT 1140ACGCCTAAAG ATGAGGTCAT TATGGAATTA GCCAAAATGT TGATTAAAAT GCAAAAAGAT 1200GCGTTTAATG GTTACGAGAT TGACTACACG CAACGAAAAT TTGTCAAAAT CATCAAAGGA 1260GCTCATGTCA TTTACTCAAA ATACCGAACT ATTAGTCTAA AGGACACTTA A1311 (2) SEQ ID NO:353 information

Sequence properties:

(A) length: 696 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...696

(xi) sequence representation: SEQ ID NO 353: ATGTTTAAAA AAATCATTTT TTTGTGCGTT TTTTTGATAG GGGGATTTGT CATTCCACCC 60CTTGAAGCCA TGCCTATTTT GCGCAATAAA ACCCCCAAAA AAAATTACCA AGAAGCCCAT 120GAAAAGCTCT ATAGAAGCAT CATTAACCGC CAAAAGCTCA CGCGTAAAAA AAGCGGGTGG 180TATTTTTTAG GGGGGGTTGG CGCTGTAGAA GCCATTAAGG ACTATCAAGG CAAGGAAATG 240AAAGATTGGA TCGCCACGCT CAATTTAAAA ACCGGCGTGC AAAGTTTTTT TAAAAAATAC 300ATCGGGATTA GGGGGGTTTT TGCATGGGAT CTTGGGTCAG GAAAAGTGAA TTATCAAAGC 360TATAAAGATC CTACCAACTC TTTTTTTACC ATGCTTGCGG TGGGTTTGGA TGTGATCATG 420GAATTTCCTC TAGGGAGTTA TAAGCATTAT TTAGGGGCGT TTGGGGGAGC TAGGGGGGCT 480TTAGTTGTTT ATACAGACAA GCAAAATTTC AAGTTTTTTA AACATTCTGT GGTTTCAGGG 540GGATTAGCGA TTAGTGGAGG GGTCATGCTC ACGCTTTTTT TAAGGCACCG CATTGAATTA 600GGGTTTAAGA TCTTGCCCAC CGCCAGATTG CTTTCTAGCT CTAGTCGCTT TGAAACTTCG 660CCCCTATTTT ATGCGGCATA CAGCTATAAA TTTTAA 696(2) SEQ ID NO 354 information

Sequence properties:

(A) length: 1983 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1983

(xi) sequence representation: 354: ATGCTAAAAA AGATTTTTTA TGGTTTTATC GTTTTATTTT TGATTATCGT AGGGTTGTTG 60GCCGTTCTTG TCGCTCAAGT TTGGGTAACT ACGGATAAGG ATATTGCTAA AATTAAAGAT 120TATCGCCCCA GTGTCGCTTC ACAGATTTTA GACAGAAAAG GGCGTTTGAT CGCTAATATT 180TATGATAAGG AATTTCGTTT TTATGCGCGT TTTGAAGAAA TCCCCCCACG ATTTGTTGAA 240AGCCTTCTAG CGGTAGAAGA CACCCTCTTT TTTGAGCATG GGGGGATCAA TTTAGACGCT 300GTCATGCGCG CTATGATTAA AAACGCTAAA AGTGGTCGTT ACACTGAAGG GGGTAGCACT 360CTAACCCAAC AACTCGTTAA AAACATGGTG CTCACACGGG AAAAAACCCT AACCAGAAAA 420CTCAAAGAAG CTATCATCTC CATACGCATT GAAAAAGTCT TAAGCAAAGA AGAAATTTTA 480GAGCGTTATT TGAACCAAAC TTTTTTTGGG CATGGGTATT ATGGCGTGAA AACCGCAAGT 540TTAGGGTATT TTAAAAAACC CCTTGACAAA CTCACGCTTA AAGAAATCAC CATGTTAGTC 600GCCTTACCTA GGGCTCCAAG TTTTTATGAC CCTACCAAAA ATTTAGAATT TTCACTCTCT 660AGGGCTAATG ATATTTTAAG GCGGTTGTAT TCTTTAGGCT GGATTTCTTC TAACGAGCTC 720AAATCCGCTC TCAATGAAGT GCCAATCGTC TATAACCAAA CTTCCACGCA AAATATCGCT 780CCCTATGTCG TGGATGAAGT GTTGAAGCAA TTGGATCAAT TAGACGGGTT AAAAACTCAA 840GGCTATACCA TAAAACTCAC GATAGATTTG GATTACCAAC GCTTAGCGTT GGAGTCTTTG 900CGTTTTGGGC ATCAAAAAAT CTTAGAAAAA ATCGCTAAAG AGAAGCCAAA AACTAACGCT 960TCTAATGATA AAGATGAAGA CAACTTAAAC GCCAGCATGA TAGTTACAGA AACGAGCACC 1020GGTAAGATTT TAGCCTTAGT GGGGGGGATT GATTATAAAA AAAGCGCTTT CAATCGCGCC 1080ACGCAAGCCA AACGGCAGTT TGGGAGCGCG ATCAAGCCTT TTGTGTATCA AATCGCTTTT 1140GATAATGGCT ATTCCACCAC TTCCAAAATC CCTGATACCG CGCGAAATTT TGAAAATGGC 1200AATTATAGTA AAAACAGCGT GCAAAACCAC GCATGGCACC CTAGCAATTA TACTCGCAAA 1260TTTTTAGGGC TTGTAACCTT GCAAGAAGCC TTGAGCCATT CGTTAAATCT GGCTACGATT 1320AATTTAAGCG ATCAGCTTGG CTTTGAAAAA ATTTATCAAT CTTTAAGCGA CATGGGGTTT 1380AAAAACCTCC CTAAAGATTT GTCTATTGTG TTAGGGAGCT TTGCTATCTC ACCGATTGAT 1440GCGGCTGAAA AGTATTCTCT ATTTTCTAAT TACGGCACCA TGCTCAAACC CATGCTCATT 1500GAAAGCATCA CCAACCAACA AAACGAAGTC AAAACTTTCA CGCCCATTGA AACCAAAAAG 1560ATCACTTCCA AAGAACAAGC TTTTTTAACC CTTTCAGCGC TGATGGATGC GGTAGAAAAC 1620GGCACAGGGA GTTTGGCTCG CATTAAAGGT TTAGAAATTG CCGGTAAAAC CGGGACTTCT 1680AACAACAATA TTGACGCTTG GTTCATTGGC TTTACCCCCA CCTTACAAAG CGTGATCTGG 1740TTTGGGAGAG ACGATAACAC GCCTATTGGC AAAGGAGCGA CAGGAGGCGT TGTGAGCGCG 1800CCTGTGTATT CGTATTTCAT GCGCAATATC TTAGCGATTG AACCTTCTTT AAAAAGAAAG 1860TTTGATGTCC CCAAAGGCTT GCGTAAAGAA ATCGTGGATA AAATCCCCTA CTACTCAAGC 1920CCTAATTCCA TCACCCCCAC CCCCAAAAAA ACAGACGATA GCGAAGAACG CTTGTTGTTC 1980TAA 1983(2) SEQ ID NO 355 information

Sequence properties:

(A) length: 972 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...972

(xi) sequence representation: SEQ ID NO 355: ATGAAATATT TATGGCTTTT TTTAATATAC GCTATAGGGC TTTTTGCAAC AGATAAAACG 60CTAGATATTA TTAAAACCAT TCAAAAACTT CCTAAGATTG AAGTGCGCTA CTCCATAGAT 120AACGATGCCA ATTACGCTTT AAAATTGCAT GAAGTCTTAG CGAACGATTT AAAGACTAGC 180CAGCATTTTG ATGTTTCTCA AAACAAAGAG CAAGGTGCTA TCAATTACGC AGAACTCAAG 240GATAAAAAAG TCCATCTTGT AGCGCTTGTG AGCGTGGCGG TAGAAAACGG CAATAAAATT 300TCACGATTAA AACTTTATGA TGTGGATACA GGAACGCTCA AAAAGACTTT TGACTACCCC 360ATTGTAAGTT TAGATCTATA CCCTTTTGCA GCGCACAACA TGGCCATTGT GGTGAATGAT 420TATTTAAAAG CCCCTTCTAT CGCTTGGATG AAGCGCCTGA TTGTTTTTTC TAAATACATT 480GGACCAGGAA TCACAAACAT CGCACTAGCG GATTATACGA TGCGTTATCA AAAAGAAATC 540ATCAAAAACA ACCGACTCAA TATTTTCCCC AAATGGGCGA ACGCTGAGCA AACGGAGTTT 600TATTACACGC AGTATGGCGA AAAAACGCCC ATGATTTTAA AATACAACAT TCAAAAAGCC 660ACTCATGAGA ATATCGCTAG CTCTCAAGGA ATGGCTGTGG TCTCTAGCGT GAGTTCTGAT 720GGCTCTAAAA TTTTAATGTC TTTAGCCCCT GATGGCCAAC CGGATGTTTA TTTGTATGAC 780ACGCATAAAA AAACTAAAAC CAAAATAACG CGCTATCCGG GGATAGATGT TTCAGGCGTG 840TTTTTAGAAG ATGACAAGTC TATGGCTTTT GTTTCAGATA GATCCGGTTA TCCTAACATC 900TATATGAAGA AATTGGGGTT AAAAGAGAGC GCGGAGCAAC TCCTTTATGA AGGAAGAAGC 960AATGAATCCA TT 972(2) SEQ ID NO 356 information

Sequence properties:

(A) length: 3867 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...3867

(xi) sequence representation: SEQ ID NO 356: ATGGAAATAC AACAAACACA CCGCAAAATC AATCGCCCTT TAGTTTCTCT CGTTTTAGCA 60GGAGCGTTGA TTAGCGCCAT ACCGCAAGAG AGTCATGCCG CCTTTTTCAC GACCGTGATC 120ATTCCAGCCA TTGTTGGGGG TATCGCCACA GGCACTGCTG TAGGAACGGT CTCAGGGCTT 180CTTAGTTGGG GACTCAAACA AGCCGAAGAA GCGAATAAAA CCCCAGATAA ACCCGATAAA 240GTTTGGCGCA TTCAAGCAGG AAAAGGCTTT AATGAATTTC CTAACAAGGA ATACGACTTA 300TACAAATCCC TTTTATCCAG TAAGATTGAT GGAGGTTGGG ACTGGGGGAA CGCCGCTAGG 360CATTATTGGG TCAAAGGCGG GCAATGGAAC AAGCTTGAAG TGGATATGAA AGACGCTGTA 420GGGACTTATA AACTATCAGG GCTTAGAAAC TTTACTGGTG GGGATTTAGA CGTGAATATG 480CAAAAAGCCA CTTTGCGTTT GGGCCAATTC AATGGCAATT CTTTCACAAG CTATAAGGAT 540AGCGCTGATC GCACCACGAG AGTGAATTTC AACGCTAAAA ATATTTCAAT TGATAATTTT 600GTAGAAATCA ATAATCGTGT GGGTTCTGGA GCCGGGAGAA AAGCCAGCTC TACGGTTTTG 660ACTTTGCAAG CTTCAGAAGG GATCACTAGC AGTAAAAATG CGGAAATTTC TCTTTATGAT 720GGCGCCACGC TCAATTTGGC TTCAAACAGC GTTAAATTAA ATGGTAATGT GTGGATGGGC 780CGTTTGCAAT ACGTGGGAGC GTATTTAGCC CCTTCATACA GCACGATCAA CACTTCAAAA 840GTTCAAGGGG AAGTGGATTT TAACCATCTC ACTGTGGGGG ATCAAAACGC CGCTCAAGCG 900GGCATTATCG CTAGCAATAA GACTCATATT GGCACACTGG ATTTGTGGCA AAGCGCCGGG 960TTAAATATCA TTGCCCCTCC AGAAGGTGGC TACAAGGATA AACCTAATAG TACCACTTCT 1020CAAAGTGGCA CTAAAAACGA CAAGAAAGAG ATCAGTCAAA ATAACAATAG CAACACAGAG 1080GTCATTAACC CACCCAATAA CACGCAAAAA ACAGAAACTG AACCCACGCA AGTCATTGAT 1140GGGCCTTTTG CTGGCGGCAA AGACACGGTT GTCAATATTT TCCACTTAAA CACTAAAGCC 1200GATGGCACGA TTAAAGTGGG AGGGTTTAAA GCTTCTCTTA CCACGAATGC GGCTCATTTG 1260AATATCGGCA AAGGCGGTGT CAATCTGTCC AATCAAGCGA GCGGGCGCAC CCTTTTAGTG 1320GAAAATCTAA CCGGGAATAT CACCGTTGAT GGGCCTTTAA GAGTGAATAA TCAAGTGGGT 1380GGCTATGCTT TGGCAGGATC AAGCGCGAAT TTTGAGTTTA AGGCTGGTGT GGATACTAAA 1440AACGGCACAG CCACTTTCAA TAACGATATT AGTTTGGGAA GATTTGTGAA TTTAAAGGTG 1500GATGCTCATA CAGCTAATTT TAAAGGTATT GATACGGGTA ATGGTGGTTT CAACACCTTA 1560GATTTTAGTG GTGTTACAGA CAAAGTCAAT ATCAACAAGC TCATCACAGC TTCCACTAAT 1620GTGGCCGTTA AAAACTTCAA CATTAATGAA TTGATTGTTA AAACCAATGG GATAAGTGTG 1680GGGGAATACA CTCATTTTAG CGAAGATATA GGCAGTCAAT CGCGTATCAA TACCGTGCGT 1740TTGGAAACTG GCACTAGGTC AATCTTTTCT GGGGGTGTCA AATTTAAAAG CGGTGAAAAA 1800CTAGTTATCA ATGATTTTTA CTATAGCCCT TGGAATTATT TTGACGCTAG GAATGTTAAA 1860AATGTTGAAA TCACCAGAAA ATTCGCTTCT TCAACCCCAG AAAACCCTTG GGGCACATCA 1920AAGCTCATGT TTAATAATCT AACCTTGGGT CAAAATGCGG TCATGGACTA TAGTCAATTT 1980TCAAATTTAA CCATTCAGGG GGATTTTATC AACAATCAAG GCACTATCAA CTATCTGGTC 2040CGAGGCGGGA AAGTGGCAAC CTTAAATGTA GGCAATGCAG CAGCTATGAT GTTTAATAAT 2100GATATAGACA GCGCGACCGG ATTTTACAAA CCGCTCATCA AGATTAACAG CGCTCAAGAT 2160CTCATTAAAA ATACAGAGCA TGTTTTATTG AAAGCGAAAA TCATTGGTTA TGGTAATGTT 2220TCTACAGGTA CCAATGGCAT TAGTAATGTT AATCTAGAAG AGCAATTCAA AGAGCGCCTA 2280GCCCTTTATA ACAATAATAA CCGCATGGAT ACTTGTGTGG TGCGAAATAC TGATGACATT 2340AAAGCATGCG GTATGGCTAT CGGCAATCAA AGCATGGTGA ACAACCCTGA CAATTACAAG00 2400TATCTTATCG GTAAGGCATG GAGAAATATA GGCATCAGTA AAACGGCTAA CGGCTCTAAA 2460 2520TTACCCACAA ACACCACTAA TAATGCGCAT TCTGCTAACT ACGCTCTCGT GAAGAACGCT 2580CCTTTCGCTC ACAGCGCCAC TCCTAATTTA GTCGCTATCA ATCAGCATGA TTTTGGCACT 2640ATTGAGAGCG TGTTTGAATT GGCTAACCGC TCTAAAGATA TTGACACGCT CTATACTCAT 2700TCAGGCGCGC AAGGCAGGGA TCTCTTGCAA ACTTTATTGA TTGATAGCCA TGATGCGGGT 2760TATGCCAGAC AAATGATTGA TAACACAAGC ACCGGTGAAA TCACCAAGCA ATTGAATGCG 2820GCCACTGACG CTTTAAACAA CGTAGCCAGT TTAGAGCATA AACAAAGCGG CTTACAAACC 2880TTGAGCTTGA GTAATGCGAT GATTTTAAAT TCTCGTTTAG TCAATCTCTC TAGGAAGCAC 2940ACCAACCATA TTAACTCGTT CGCTCAACGC TTACAAGCTT TAAAAGGCCA AGAATTCGCT TCTTTAGAGA GCGCGGCAGA AGTGTTGTAT CAATTTGCCC CTAAATATGA AAAACCTACC 3060AATGTTTGGG CTAACGCTAT TGGGGGAGCG AGCTTGAATA GCGGCTCTAA CGCTTCATTG 3120TATGGCACAA GCGCCGGCGT AGACGCTTTC CTTAACGGGA ATGTGGAAGC CATTGTGGGC 3180GGTTTTGGAA GCTATGGTTA TAGCTCCTTT AGCAATCAAG CGAACTCTCT TAACTCTGGG 3240GCCAATAACG CTAATTTTGG CGTGTATAGC CGTTTTTTTG CCAACCAGCA TGAATTTGAC 3300TTTGAAGCTC AAGGGGCGCT AGGGAGCGAT CAATCAAGCT TGAATTTCAA AAGCACTCTA 3360TTACAAGATT TGAATCAAAG CTATAATTAC TTAGCCTATA GCGCCACAGC AAGAGCGAGT 3420TATGGTTATG ACTTCGCGTT TTTTAGGAAC GCTTTAGTGT TAAAACCAAG CGTGGGCGTG 3480AGCTATAACC ATTTAGGTTC AACCAACTTT AAAAGCAATA GCCAATCACA AGTGGCTTTA AAAAATGGCG CGAGCAGTCA GCATTTATTC AACGCTAACG CTAACGTGGA AGCGCGTTAT 3600 3660TTTGGATCGA ATGATGTGGC GTCTTTAAAC ACCTTTAAAA TCAATGCCGC TCGCAGTCCT 3720TTAAGCACCT ATGCAAGAGC GATGATGGGT GGGGAATTGC AATTGGCTAA AGAAGTGTTT 3780TTGAATTTGG GCGTGGTTTA TTTGCACAAT TTGATTTCCA ACGCAAGCCA TTTCGCTTCC 3840AATTTAGGAA TGAGGTATAG TTTCTAA 3867(2) SEQ ID NO:357 information.

Sequence properties:

(A) length: 1158 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1158

(xi) sequence representation: SEQ ID NO:357: ATGAAAGATA GTTTTCTTTT CACTTCCGAA TCAGTAACCG AAGGGCATCC TGATAAAATG 60GCCGATCAGA TCAGCGATGC GGTTTTAGAT TACATTATTG AGCGGGATAA AAAAGCCAAA 120GTCGCATGCG AGACTTTAGT TTCTAATGGT TTTTGCATGA TCACTGGCGA GTTAAAAACT 180TCTGTTTATG CCCCGATGCA AGAGATCGCA AGAGAAGTGG TTAAAAAAAT TGGCTATACA 240GACGCTCTTT ATGGCTTTGA TTACAGAAGC GCGGCGGTTT TAAATGGCAT TGGCGAGCAA 300AGCCCTGATA TTAATCAAGG CGTGGATAGA GAAGATGGGG AGATTGGGGC GGGGGATCAA 360GGGCTTATGT TTGGTTATGC ATGCAAAGAG ACTGAAACGC TCATGCCTTT ACCCATCCAT 420TTAGCGCACC AGCTCGCTTT CGCTCTAGCT CAAAAAAGAA AAGACAACAC CTTGCCTTTT 480TTAAGGCCTG ATGGCAAGTC TCAAGTGAGC GTGCGTTATG AAAACAACAA GCCTGTAAGC 540GTTGATACGA TTGTCATTTC CACCCAACAT TCCCCAGAAG TTTCACAAAA GCATTTAAAA 600GAAGCGGTGA TTGAAGAGAT CGTGTATAAG GTTTTACCCA AAGAATATTT GCATGACAAT 660ATCAAGTTTT TTATAAACCC TACAGGAAAA TTCGTCATCG GTGGGCCTCA AGGCGATGCG 720GGTTTGACAG GTAGAAAAAT CATCGTGGAT ACTTATGGAG GGTTTTGCCC GCATGGAGGG 780GGAGCGTTTA GCGGGAAAGA CCCTAGCAAG GTGGATAGGA GCGCGGCTTA TGCGGCCCGC 840TATGTGGCTA AAAATTTGGT AGCGAGCGGG GTTTGCGATA AAGCGACCGT GCAGCTTGCT 900TATGCGATTG GGGTGATAGA GCCTGTGTCT ATTTATGTGA ACACGCATAA CACGAGCAAG 960CATTCAAGCG CGGAGTTGGA AAAATGCGTG AAATCGGTTT TCAAACTCAC GCCAAAAGGC 1020ATCATTGAAA GCTTGGATTT GTTAAGACCC ATTTATTCGC TCACTTCAGC TTATGGGCAT 1080TTTGGGCGCG AGTTAGAAGA ATTCACTTGG GAAAAGACTA ACAAGGTTGA AGAGATTAAA 1140GCGTTCTTTA AGCGTTAA 1158(2) SEQ ID NO:358 information.

Sequence properties:

(A) length: 207 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...207

(xi) sequence representation: SEQ ID NO 358: ATGAAATTTT TAAACGGATT AGCAGGGAAT TTACTGATTG TGGTTATCTT ATTGTGTGTG 60GTCGTTTTTT TCGCGCTCAA AGCGATCCAT ATCCAAAAAG AGCAAGCCAC CAATTATTAC 120CGCTATAAGG ATATTAACGC TTTAGAGGCA AAAAACACCC AAAACCACGC TAATTATGAA 180TTAGTCAATC AAGGGAGTAA AAAATGA 207(2) information SEQ ID NO 359

Sequence properties:

(A) length: 1509 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1509

(xi) sequence representation: 359: TTGAAAATCT TTTTAGTTAT TCTAAGCGTC TTTTTTTTTA ATGGGTGTTT TGGGCTAGTC 60TATAAGACTC CCATTTCAAA CCCCCCTATC TCTTATGACC CCTACACTAC CACCATTGGG 120AGCTTGTATG CTAAAAATTT AAAAGAAAAC CCTAAACATA GTGCGGCCAT TCTTTTAGAA 180GACGGCTTTG ATGCCTTGTT GCACAGAGTG GGTCTTATTA GAATGAGCCA AAAAAGCATT 240GACATGCAAA CTTATATCTA TAAAAACGAC CTTTCTTCTC AAGTGATCGC TAAAGAACTT 300TTAAACGCGG CCAATCGTGG GGTAAAAGTG CGCATCCTTT TAGATGACAA CGGGTTAGAT 360TCAGATTTTT CAGACATCAT GCTTTTAAAT TTCCACAAAA ACATTGAAGT GAAAATCTTT 420AACCCCTACT ATATCCGCAA TAAAGGCTTG CGTTATTTTG AAATGCTTGC GGATTATGAA 480CGCATTAAAA AACGCATGCA CAACAAGCTT TTCATCGTGG ATAATTTCGC TGTCATTATA 540GGGGGGCGCA ACATTGGGGA CAATTATTTT GATAACGATT TAGACACGAA TTTTTTAGAT 600TTAGACGCTT TGTTTTTTGG GGGGGTTGCT TCAAAGGCCA AAGAAAGCTT TGAAAATTAT 660TGGCGATTCC ACCGCTCTAT CCCTGTTTCA TTATTAAGkA CCCATAAAAG ACTCAAAAAC 720AACGTTAAAG AAATCGCTAA GCTCCATGAA AAAATCCCTA TCAGCGCTGA AGACGCAAAC 780GAATTTGAAA AAAkAGTCAA TGATTTTATA GAACGCTTCC AAAAATACCA ATACCCCATT 840TATTATGGGA ATGCCATTTT TCTAGCCGAT TTGCCCGCCA AAATTGACAC GCCCTTGTAT 900TCGCCCATCA AAATCGCTTT TGAAAAAGCC CTTAAAAACG CTAAAGACTC CGTTTTTATC 960GCTTCATCGT ATTTTATTCC AGGTAAAAAG ATAATGAAAA TCTTTAAAAA TCAAATTTCT 1020AAGGGGATTG AATTGAATAT TCTTACCAAT TCCCTTTCAT CTACGGACGC TATCGTGGTC 1080TATGGGGCGT GGGAAAGGTA TCGCAATAAA TTAGTGCGAA TGGGCGCGAA TGTCTATGAA 1140ATACGAAACG ATTTTTTCAA CCGCCAGATT AAAGGGCGCT TTAGCACCAA ACATTCCTTA 1200CACGGCAAGA CAATTGTTTT TGACGATGCC CTAACGCTTC TAGGGAGTTT TAATATTGAT 1260CCGCGCTCTG CATATATTAA CACTGAAAGT GCGGTCTTGT TTGACAACCC GTCTTTTGCC 1320AAAAGGGTGC GTTTGTCGCT TAAAGATCAT GCCCAACAAT CATGGCATTT AGTCTTGTAT 1380CGGCATAGAG TGATTTGGGA AGCTACAGAA GAAGGCATCT TAATCCATGA AAAAAACTCG 1440CCTGATACCT CTTTCTTTTT GCGTTTGATT AAAGAATGGT CTAAAGTCCT TCCTGAAAGA 1500GAACTTTAA 1509(2) SEQ ID NO 360 information

Sequence properties:

(A) length: 534 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...534

(xi) sequence representation: SEQ ID NO 360: ATGCGTTTTA GTTACATTGA GCCAAGAGCG AAATACTTAA TCAGCAAGCT TTCTAAAATT 60TGGGTTTTTT ACATTTTTTT ATCTTTTGTG CTAATAGGGG GGTTAGTGTG GTTTATGCAC 120AACGCCATTA AACGCGCTCA AGACAACGCG TCTAGTTTGA CGATCCAAGA AAGGCTTTAC 180CGCCATGAAA TCAGCCGCTT GCAGGTAAAG ACTGATGAAA CTTTAAAACT CATTAAAGAA 240GCCAAAAAGC GTTTGAATTA TAACGATGAT ATACGAGATG TTTTGCAAGG GCTTTTGAAT 300ATTGTGCCGG ATCTTATCAC CATTAATAGC ATTGAAATAG ACCAACAAAG CGTGGTGGTT 360AGCGGTAAAA CCCCCTCTAA AGAAGCCTTT TACTTTTTGT TTCAAAACAA ACTAAACCCC 420ATGTTTGATT ATTCTAGGGC GGAATTTTTC CCTTTAAGCG ACGGGTGGTT TAATTTTGTC 480TCCACCAACT TTTCTAATTC CTTACTGATA AAAAACCCGG AGTCTATTAA ATGA 534(2) SEQ ID NO 361 information

Sequence properties:

(A) length: 669 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...669

(xi) sequence representation: SEQ ID NO 361: ATGCGTAAGA TCTTGTTAAT GGGCTTGATT TTACAAGCGC TCTTTGGCGA AGAAGCCGCG 60CAAGAATTGT TGCAATGCTC TGCGATTTTT GAATCTAAAA AAGCCGAATT GAAAGAGGAT 120TTGCGCCAAT TGAGTGAAAA AGAGCAGTCT TTGAGGATCT TGCAAACCGA AAACGCCCGC 180CTTTTAGATG AAAAAAGCGA TCTGTTAAAC AAGAAAGAAA AAGAAATAGA CGAAAAACTG 240AAAAATTTAG CCGCTAAAGA AGAAGCCTTT AAAACCTTAC AAACAGAAGA AAAAAACGC 300CTTAAAAATT TGATAGAAGA AAATGAAGGC ATTTTAAGAG AAATCAAGCA GGCTAAAGAC 360AGCAAGATTG GCGAGACTTA TTCTAAAATG AAAGATTCTA AATCGGCTCT GATTTTAGAA 420AATTTACCCA CTCAAAACGC TTTAGAAATT TTAATGGCGC TAAAGCCTCA AGAATTAGGC 480AAAATTCTAG CCAAAATGGA TCCTAAAAAA GCGGCGGCTT TGACAGAGTT GTGGCAAAAA 540CCCCCAAAAG AAAATAAAGA AAATAAAGAA AGCCAAAAAA CCACAGATCC CACGCCCCCC 600ACACCACCCA CGCCTCCTAA AGAGCCAACC CTAAAAGATC CTAATGTAAA AGAGCCAACA 660GGGGTATGA 669(2) SEQ ID NO 362 information

Sequence properties:

(A) length: 1296 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1296

(xi) sequence representation: SEQ ID NO 362: ATGAATATTC AAACAAAGAA AAGATTTTTA GCAAATTTAT TGCTTTTTAG CCTGTTTTCT 60TGCCTTAAGG CTGAAACCCT TTCAGAAGAC CATCAAATCC TGTTGAGTTC AGACGCTTTC 120CATAGAGGGG ATTTTGCCAC CGCTCAAAAA GGCTATATGA ATCTCTATAA GCAAACCAAT 180AAAGTGGTGT ATGCTAAAGA GGCGGCCATT TCAGCGGCGA GTTTAGGGGA CATTAAAACC 240GCTATGCATT TAGCCATGCT TTATCAAAAA ATCACCAATA ATCGTAACGA TGTTTCTATC 300AATAAGATTT TAGTGGATGG CTATGCACAA ATGGGGCAGA TTGATAAGGC GATTGAACTA 360TTACACAAGA TTCGTAAGGA AGAAAAAACC ATAGCCACAG ACAATGTGTT AGGGACTTTG 420TATTTGACTC AAAAGCGTTT GGATAAGGCT TTCCCGTTGT TGAATAAGTT TTATAACCAA 480GTGCATGATG AAGACAGCCT AGAAAAACTC ATTATGATCT ATTTTTTACA AAACCGCAAA 540AAAGAGGGTT TGGATCTGTT GCAATCTCAT ATAGACAGGT ATGGTTGCTC AGAGCAATTG 600TGCCAAAAAG CGCTCAACAC CTTCACGCAA TTTAACGAGC TTGATTTGGC TAAAACGACT 660TTCGCTCGTT TGTATGAAAA AAACCCTATT GTTCAAAACG CCCAATTTTA CATAGGGGTA 720TTAATCTTGT TAAAAGAGTT TGATAAGGCC CAGCAAATCG CAGAATTATT CCCCTTTGAC 780AGGCGTTTGT TGCTAGACTT ATACACCGCG CAAAAAAAAT TTGATCAAGC TTCCAAACAG 840GCTTCTTTAA TCTATCAAGA AAGAAAAGAC CCTAAATTCT TAGGCTTAGA GGCGATTTAT 900CATTATGAAA GCTTGAGCGC GAATAAGAAA AAGCTCACCA AAGAAGAGAT GTTGCCCATC 960ATTCAAAAAT TAGAGCAAGC CACCAAAGAG CGCCAAGCAT GGCTTGCTAA AACTAAAGAT 1020AAAGAAGACG CGCAAGACGC TTTCTTTTAT AATTTTTTAG GGTATTCCTT AATAGATTAT 1080GACATGGATG TTAAAAGGGG CATGGATCTT GTGAGGAAAG CCTTAGCGTT AGATTCTAAC 1140TCAGTGCTTT ATTTGGATTC TTTAGCATGG GGTTATTACA AATTAGGGAA TTGTTTGGAG 1200GCTAAAAAAA TCTTTTCTAG CATCGCTAAA GAGCTTATCC AAAACGAACC CGAATTGAAA 1260GAACACAATA AAATCATTCA AGAATGCAAG AAATAG 1296(2) SEQ ID NO 363 information

Sequence properties:

(A) length: 294 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...294

(xi) sequence representation: SEQ ID NO 363: ATGCTTTATG CATCAAAAGC GCGTTTATTT TTACAAATCA AAGGAAAGTT TATGTTAAGA 60ATTTTAATCC CCTTACTCAT TATTGTGTGG GTTTTATGGC GTTTGTTTTT GAGGCAAAAA 120CCCCACAAAG ATGACCACAG AGACAACCAC TCTTACACGC AACAAACCCC CAAAGAATTA 180GAAGATCACA TGATTGTATG CTCTAAATGC CAAACTTATG TCTCTAGTAA AGACGCCATT 240TATAGTGGGG CGGTAGCCTA TTGCAGTGAA ACTTGTTTGA AGGATAAGGG GTAA 294(2) SEQ ID NO 364 information

Sequence properties:

(A) length: 1440 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1440

(xi) sequence representation: 364: ATGAAAAATA GCGCGCCTTT AAAGAATAAA GTTTTTTGTG GGTTATACGT TTTAAGTTTA 60AGCGCTTCTG TGCAAGCGTT TGATTATAAA ATTGAAGTTT TGGCAGAGTC CTTTTCTAAA 120GTTGGCTTTA ATAAAAAAAA GATTGACATA GCTAGGGGGA TTTATCCTAC AGAGACTTTT 180GTAACCGCTG TGGGTCAGGG CAATATTTAT GCGGATTTTT TATCCAAAAG CCTTAAAGAT 240CAAGGGCATG TTTTAGAGGG AAAAGTCGGC GGCACAATCG GTGGGATTGC TTATGACAGC 300ACGAAATTCA ATCAAGGCGG ATCGGTTATT TATAATTATA TCGGTTATTG GGATGGCTAT 360TTAGGGGGTA AAAGGGCCTT GCTTGATGGC ACGAGTATCC ATGAGTGCGC GCTTGGCTCT 420GATGGCAAGG TGATTGATTC TATAGCGTGC GGGAACGCTA GAGCCAATAA AATCCGCCGT 480AATTACTTGA TGAATAACGC TTTTTTAGAA TACCGCTATA AGGATATATT TGCGGCTAAA 540GGGGGGCGTT ATCAATCCAA TGCTCCTTAT ATGAGCTCTT ATACGCAAGG CTTTGAAATC 600AGCGCTAAAA TCAAGGATAA AAATGAGGGG AGCCATAAAT TATGGTGGTT TAGCTCATGG 660GGTAGGGCGT TCGCTTATGG GGAGTGGATT TATGATTTTT ACTCTCCAAG AACCGTGATT 720AAAAACGGGC GCACTCTAAA TTATGGTATC CATTTAGTGG ATTACACTTA CGAAAGGAAA 780GGGGTTAGCG TCAGCCCCTT TTTCCAGTTT TCGCCCGGGA CTTATTATAG CCCTGGGGTG 840GCTGTAGGCT ATGATAGTAA CCCTAATTTT AATGGCGTGG GCTTTAGATC CGAAACGAAG 900GCTTATATTT TGCTCCCTGT CCATGCCCCC CTTAAAAGGG ATACTTATCG TTACGCTGTG 960AAAGCTGGCA CCGCTGGGCA AAGCCTGCTC ATTAGGCAAC GATTTGATTA CAATGAATTT 1020AACTTTGGGG GAGCGTTTTA TAAAGTATGG AAAAACGCAA ACGCTTACAT AGGCACGACA 1080GGAAACCCTC TAGGCATTGA TTTTTGGACC AATAGCGTTT ATGATATAGG GCAAGCCTTA 1140AGCCATGTGG TAACCGCTGA TGCCGTCTCT GGTTGGGTTT TTGGTGGAGG CGTGCATAAA 1200AAATGGCTGT GGGGGACTTT GTGGCGTTGG ACTAGCGGCG CTTTAGCCAA TGAAGCGAGC 1260GCGGCTGTTA ATGTGGGCTA TAAGATCAGT AAGAGTTTGA CAGCGAGCGT GAAATTAGAA 1320TATTTGGGCG TGATGACGCA TTCAGGCTTT ACGGTAGGGA GTTACAGACC CACGCCCGGC 1380TCTAAAGCAC TTTATTCAGA CAGGAGCCAT CTAATGACAA CCCTTAGCGC CAAATTCTAA 1440(2) SEQ ID NO 365 information

Sequence properties:

(A) length: 1440 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1440

(xi) sequence representation: SEQ ID NO 365: ATGAAAAATA GCGCGCCTTT AAAGAATAAA GTTTTTTGTG GGTTATACGT TTTAAGTTTA 60AGCGCTTCTG TGCAAGCGTT TGATTATAAA ATTGAAGTTT TGGCAGAGTC CTTTTCTAAA 120GTTGGCTTTA ATAAAAAAAA GATTGACATA GCTAGGGGGA TTTATCCTAC AGAGACTTTT 180GTAACCGCTG TGGGTCAGGG CAATATTTAT GCGGATTTTT TATCCAAAAG CCTTAAAGAT 240CAAGGGCATG TTTTAGAGGG AAAAGTCGGC GGCACAATCG GTGGGATTGC TTATGACAGC 300ACGAAATTCA ATCAAGGCGG ATCGGTTATT TATAATTATA TCGGTTATTG GGATGGCTAT 360TTAGGGGGTA AAAGGGCCTT GCTTGATGGC ACGAGTATCC ATGAGTGCGC GCTTGGCTCT 420GATGGCAAGG TGATTGATTC TATAGCGTGC GGGAACGCTA GAGCCAATAA AATCCGCCGT 480AATTACTTGA TGAATAACGC TTTTTTAGAA TACCGCTATA AGGATATATT TGCGGCTAAA 540GGGGGGCGTT ATCAATCCAA TGCTCCTTAT ATGAGCTCTT ATACGCAAGG CTTTGAAATC 600AGCGCTAAAA TCAAGGATAA AAATGAGGGG AGCCATAAAT TATGGTGGTT TAGCTCATGG 660GGTAGGGCGT TCGCTTATGG GGAGTGGATT TATGATTTTT ACTCTCCAAG AACCGTGATT 720AAAAACGGGC GCACTCTAAA TTATGGTATC CATTTAGTGG ATTACACTTA CGAAAGGAAA 780GGGGTTAGCG TCAGCCCCTT TTTCCAGTTT TCGCCCGGGA CTTATTATAG CCCTGGGGTG 840GCTGTAGGCT ATGATAGTAA CCCTAATTTT AATGGCGTGG GCTTTAGATC CGAAACGAAG 900GCTTATATTT TGCTCCCTGT CCATGCCCCC CTTAAAAGGG ATACTTATCG TTACGCTGTG 960AAAGCTGGCA CCGCTGGGCA AAGCCTGCTC ATTAGGCAAC GATTTGATTA CAATGAATTT 1020AACTTTGGGG GAGCGTTTTA TAAAGTATGG AAAAACGCAA ACGCTTACAT AGGCACGACA 1080GGAAACCCTC TAGGCATTGA TTTTTGGACC AATAGCGTTT ATGATATAGG GCAAGCCTTA 1140AGCCATGTGG TAACCGCTGA TGCCGTCTCT GGTTGGGTTT TTGGTGGAGG CGTGCATAAA 1200AAATGGCTGT GGGGGACTTT GTGGCGTTGG ACTAGCGGCG CTTTAGCCAA TGAAGCGAGC 1260GCGGCTGTTA ATGTGGGCTA TAAGATCAGT AAGAGTTTGA CAGCGAGCGT GAAATTAGAA 1320TATTTGGGCG TGATGACGCA TTCAGGCTTT ACGGTAGGGA GTTACAGACC CACGCCCGGC 1380TCTAAAGCAC TTTATTCAGA CAGGAGCCAT CTAATGACAA CCCTTAGCGC CAAATTCTAA 1440(2) SEQ ID NO 366 information

Sequence properties:

(A) length: 516 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type ofmolecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...516

(xi) sequence representation: SEQ ID NO 366: ATGGGCTTGA AAAATCTCTC AACACTTCTG GTGTTTTTAT TCTTTTGTTT GGGGTGTGTG 60AGCAATTTTA ATGAAGACAC TTACACGCTA GACTTAGTTT TAGAAAAAAA GATCCAAGCC 120AGTAGGAAAG GCGAAATCAC CCAAGATAAT GTGCCTATCA TCACGGCTAT CGCTACGCAT 180TTAAACGATG TGGATAGCGG CACTTACTAC GATCATGAGT ATTTTTTAGT GGAGATTTTC 240ACGCAAAATA ACGACTGGAT AGATGATGGC TATATTTCTT ATGAACTTTT TGGCACAAAA 300CCTACAGGAT CAGAACCTTT ATGGGTGCGA GAGATTACAA GAGATGAATT TGATGGCATT 360TTAGAAACCA CGAACCGGTG GAGCCGAGCC TTTTTGATCG CTTTTGACAA ATTGGATTAT 420TTAGCGGTGC AAGAAGCCAA ACTAGAGCTT GATGCCTATA GTTTAGGCAA AATTGTTTTT 480AATTTCGCTT ACCAAGTCCC CTTACCTCAA TTTTAA 516(2) SEQ ID NO 367 information

Sequence properties:

(A) length: 255 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...255

(xi) sequence representation: SEQ ID NO 367: GTGAATAAAA AGCACCGCTT GGCTTTTTTA GGGCTAATTG TTGGGGTTCT ATTCTTCTTT 60AGCGCGTGCC AACACCGCCT GCACATGGGG TATTATTCAG AAGTTACAGG GGATTATTTG 120TTCAATTATA ATTCCACTAT CGTGGTGGCT TATGACAGAA GCGATGCGAT GACTTCTTAT 180TATATCAATG TGATTGTTTA TGAATTGCAA AAATTAGGCT TTTATAATGT CTTCACGCAA 240GCGAATTCCC GCTAG 255(2) SEQ ID NO 368 information

Sequence properties:

(A) length: 756 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...756

(xi) sequence representation: SEQ ID NO 368: ATGCAATATA AGAAAAATAA GAAAAGATAT TATCATTTAG CGTTAGGGAT CCTTTTTTGT 60AATGGTCTGT CTTTGAAAGC TTTAGAAATT GCCGTCAAAC CCTTTGGCTA TCTGGGGCTA 120TTGTATAATC AAGGGACGCA AAAAAACCCT CACAGCTATG TGGGGGCTTT AGCGCGTCTT 180GGGGTGGATT TTTCTTATAG CAATGGGTGG TCGTTTGGTA TTGGGGCTAT TGGGGCTTGG 240AATATTTATA ACAAACAGCG TTTGGCTAAC CTTTACATCA GTCTAGGGAA TTTTTTTGGT 300AACCCTAACA ACGTTAAGCC TTATTTGAGC GCCGGCGATG TTTCTGATGC GTATCTTCAA 360TACGCTAACC AGCGTTTTAA AATCGCTTTA GGGCGTTTTA ATACCGATTT TGTGGATTTT 420GATTGGATAG GGGGCAATAT TCAAGGGGTC TCTGTGGCTT TCAAGCAAAA TTCCATGCGT 480TATTTTGGGA TTTTTATGGA TAGCATGCTT TATAATGGGC ATCAAATCAA TAAAGAGCAA 540GGGAATCGGA TCGCCACTTC CCTAAACGCT CTAGCGTCTT ATGATCCTGT GTCTAAACGC 600TTGTATGTAG GGGGGGAAGT GTTTGTTTTG GGCGCAGAAT ACAAAAATAA AAATTTGATA 660TTCGTTCCTT TTATTTTAAC GGACACCCGC TTGCCTTTGC CCACCCAAAA TGTTTTAGTG 720CAAGTGGGGG GTAAGTTGGA GTATCGACGC TTCTTT 756(2) SEQ ID NO 369 information

Sequence properties:

(A) length: 696 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...696

(xi) sequence representation: SEQ ID NO 369: ATGGTGCAAA AAATTGGCAT TTTAGGGGCG ATGAGAGAAG AAATAACCCC TATACTAGAA 60TTGTTTGGCG TGGATTTTGA AGAGATCCCT TTAGGGGGGA ATGTTTTCCA TAAAGGCGTT 120TATCATAATA AGGAAATCAT TGTCGCTTAT AGCAAGATTG GCAAGGTGCA TTCCACTTTA 180ACCACAACAA GCATGATTTT AGCGTTTGGC GTTCAGAAGG TGCTTTTTAG CGGGGTGGCT 240GGAAGCTTAG TTAAAGATTT AAAAATCAAT GATTTGTTAG TGGCTACTCA ATTAGTCCAG 300CACGATGTGG ATTTGAGCGC GTTTGATCAC CCTTTAGGGT TTATCCCCGA AAGCGCGATT 360TTTATTGAAA CGAGTGGAAG TTTAAACGCT TTAGCTAAAA AGATCGCTAA TGAGCAACAT 420ATCGCGCTCA AAGAAGGCGT CATCGCATCA GGCGATCAGT TTGTGCATAG CAAAGAAAGG 480AAAGAATTTT TAGTTAGCGA GTTTAAAGCG AGCGCGGTGG AAATGGAGGG GGCGAGCGTG 540GCGTTTGTGT GCCAAAAATT TGGCGTGCCA TGCTGCGTGC TAAGGAGCAT TAGCGATAAC 600GCCGATGAAA AAGCCGGTAT GAGTTTTGAT GAATTTTTAG AAAAAAGCGC TCACACTTCA 660GCGAAATTCT TAAAAAGCAT GGTGGATGAG CTTTAG 696(2) SEQ ID NO 370 information

Sequence properties:

(A) length: 678 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...678

(xi) sequence representation: SEQ ID NO 370: ATGAGAGCTA CGGCGATAAA AATCTTTTCA TTCTCATCAG CGCTCGCCCT ATTGCTTCAG 60GGTTGCTTGA GCATTAATTT AAAACAAATG CTGCCAGAAA TCAGAACTTA TGATTTAAAT 120GCGAGTTCTT TTGAAATGAC GCAATGCCCT AAACCTTTGA CTGAAGTGAG GCTCATTAGC 180ATTTTGAGCG CGGATTTATT CAACACTAAA GAGATCGTGT TTAAAGCGCA AGACGGGCAG 240ATCACGCATG GGAAGCACCA AAAATGGATA GACTTGCCTC GCAACATGTT AAAAACCATG 300TTCATGCAAG AAGCGCAAAA AGCATGCTTA GGCGTGGCTT TGCCCCCTTA TGGCGCGGGC 360GCGCCCACTT ATGCGGTTCG TTTTACGATT TTATCGTTTT CTCTTTTAGA AAAAGAAAAT 420TCTACTTACA GGGCGGAATT CGCGCTAGGC TATGATATTA GCGTGAAAGG CGATTCGCAT 480TCTGGAGTGA TCATTAAGCA TGAAAATATT TCTAGCTTGG AAAATAAAAC GACCAAAACG 540AGTAAAAATG GCAGTCAAGA TTTCCAAGAA AGCGCGATAC AATCCCTCCA ACATGTCAGC 600ACGCAAGCGA TGCAAGAAGC GATTTCTTTG ATTAAAAAAG CGGTTGAAGC GCAAAGCGTA 660AGCCCGTTAA AAAAATAA 678(2) SEQ ID NO 371 information

Sequence properties:

(A) length: 816 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...816

(xi) sequence representation: SEQ ID NO 371: TTGGAAAGGC ATGTGAATTA CACTTTAATC GGCGGGCTCT TCTTTTTATG CTTAGTGTGC 60ATGGTAGGCT TTATTTTATG GCTAGGCCAT TTGGGATTAG ATGATGGGAA GTATTATGAA 120TATGTGGTCT ATACGGACAA AGACTTGGGA GGCATTGCGA CCAACTCGCC CATTAATTAC 180AAAGGGATTC AAGTGGGTAA TGTCATCAAA GTGGGTTTTG CAAAGGATAA AGTGGGGGTG 240GTCCGTTTGG ATTTGATGAT CAAATCCAGC GTTAAGATCC GTAAAGATTC CAAAGTGGCG 300GTTTCTTCTA GAGGGTTTAT GGGGTTAAAA TTTTTAGCCT TAGAGCAAAG CCACAATGAA 360GAATTTTATG GTAGCGGCGA TAAAGGGGAG CGGATTTTAA TCTTTAAAGA AGGGCTTATG 420GATCGCTTGA GCGGTGATGC TAATCAAGTG GTGCAAGAAG TGATGAAAGC GATCAGGAAT 480GTGAATAGGA TTTTAGACGA TGAAAACGTG GAGAAATTCA AGCACATTCT CGCTTCAGTG 540GATGATCTCA TCGCTAACTT GGATTCAAGA AAGACTCAAT TTGATTCCTT GATCAACAAC 600GCTAACAACC TTGTTTCTAA TGTCAATAAT GTGGCTTTGG ATGTGGATAA ACGCGTCAAA 660CAGGGGCAAT ACGACTTTAA GGCGATGTTC ACTCCTTTAA TCATGCAAGC GCAGTTGAGC 720TTAAGAAACA TTGATAATTT TGTGGAAAAA GGCTCTGCTT TGATAGATAA ATTTGACGCT 780AACCCCTATA AAACGATTTT TGGAGAAAGG AAATAA 816(2) SEQ ID NO 372 info 372

Sequence properties:

(A) length: 1053 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1053

(xi) sequence representation: SEQ ID NO 372: ATGAAAAAAA CTATTCTATT GAGCGCTCTT TTAGCTTTTT CTTGCGCTCA TGCTTTAAGC 60GATATGGATT TGATTAAAAA AGCGAAGGAA AGCCAATTAG AACCCATGCC TATGGGCAAA 120GCGCTCAAAG AATACCAGAT CAAAAAAACC AGAGATGTGG GCATTGGCGC TAAAAACAGC 180GAAATCATGA CCTCCGCTCA AGTGGAATTA GGCAAAATGC TCTATTTTGA CCCTAGGATT 240TCCACTTCCT ATCTTGTGTC TTGCAACACA TGCCATAATT TGGGCTTAGG CGGGGTGGAT 300CTAATCCCAA GCGCTATAGG CTCTCAATGG AAGAAAAACC CCCACCTTTT AAGTTCCCCA 360ACGGTGTATA ACTCTGTGTT TAACGATGTG CAGTTTTGGG ATGGTAGGGT TACGCATTTA 420AACGAACAAG CGCAAGGGCC AATCCAATCT TCTTTTGAAA TGGGGGCTGA TCCTAAAGTC 480GTGGTAGAAA AAATCAATTC CATACCAGGC TATGTCAAGC TCTTTAGAAA AGCTTATGGC 540TCTAAAGTCA AAATTGATTT TAAATTGATC GCTGATAGTA TCGCTATGTT TGAAGCCACG 600CTCATTACCC CAAGCCGTTA CGATGATTTT TTAAGGGGCA ATCCTAAAGC GCTCAGTAAA 660GCCGAAAAAG AAGGGCTGGA TTTATTCATT TCTAAAGGCT GTGTGGCGTG TCATAATGGC 720ATCAATCTTG GGGGGACGAT GCAGCCTTTT GGGGTGGTCA AACCTTATAA ATTCGCTAAT 780GTGGGCGATT TCAAGGGCGA TAAAAACGGG CTTGTGAAAG TGCCTACTTT AAGGAATATC 840ACCGAAACGA TGCCTTATTT CCATAACGGG CAATTCTGGG ATGTTAAGGA TGCGATTAAA 900GAAATGGGCT CTATCCAGTT AGGCATTGAA ATCAGCGATG CAGAAGCGAA AAAGATTGAA 960ACCTTCTTTG AAGCCTTAAA GGGTAAAAAA CCTAAAATAA TCTATCCAGA ACTCCCTGTG 1020ATGACAGACA AAACCCCTAA ACCCTCTTTT TGA 1053(2) SEQ ID NO 373 information

Sequence properties:

(A) length: 222 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...222

(xi) sequence representation: SEQ ID NO 373: ATGATGGATT TAGAAAGTTT GAGAGGTTTT GCGTATGCGT TTTTTACCAT TCTTTTTACG 60CTCTTTTTGT ATGCTTATAT TTTTAGCATG TATAGAAAGC AAAAAAAGGG CATCGTGGAT 120TATGAGCGAT ACGGGTATTT AGCGTTAAAT GATGCTTTAG AAGACGAGTT GATTGAACCA 180CGCCATAAAG AAGTTCATGA TAAAGGCATA AAGGAAAGTT GA 222(2) SEQ ID NO 374 message

Sequence properties:

(A) length: 828 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...828

(xi) sequence representation: SEQ ID NO 374: TTGCTAGATG TCAAAGCCAA TTCCCCCGCC TATCAAGCGG TGCTTTTAGC ATTGAACGCT 60GCAGTGGGCT TGTGGCAAGT TACAAGCTAT GCCTTTACCG CTTGTGGTCC TGGTAGCAAT 120GAGAACGCGA ATGGAGGTAT CCAAACCTTT AATAATGTGC CAGGACAAAA CACGACGACC 180ATCACTTGTA ATTCGTATTA TGAGCCAGGA CATGGCGGGC CAATATCCAC TGAAAATTAT 240GCGATCATCA ACAAGGCTTA TCAAATCATT CAAAAGGCTT TGACAGCCAA TGGAGAAGGG 300ATCCCAGTTT TAAGCAACAC CACTACAAAA CTTGATTTCA CTATCAATGG AGACAAAAGA 360ACGGGTGGCG AACCAAATAA AAAATTAGTA TACCCATGGA GTCATGGGAA ACCTATTTCA 420ACCTCGTGGA ATGCAACCAT AACAGTACCA ACAACAGAAA ATATCAATAC AACCAATAGC 480GCTCAAGAGC TTTTAAAACA AGCGAGCATC ATTATCACTA CCCTGAATAG TGCATGCCCA 540AACTTCCAAA ATGGTGGTAG CGGTTATTGG GCAGGGATAA GTGGCAATGG GACAATGTGT 600GGGATGTTTA AGAATGAAAT CAGCGCTATC CAAGGCATGA TCGCTAACGC GCAAGAAGCT 660GTCGCGCAAG CCAAAATCGT TAGTGAAAAC ACGCAAAATC AAAACAGCCT AGACGCTGAA 720AACCATTCAA CCCCTACACA GACGCTAGTT TTGCTGAAAG CATGCTCAAA AACGCGAAGC 780CCAAGCGGAG ATTTTAAACC AAGCCGAACA AGTGGTGAAA AACTTTGA 828(2) SEQ ID NO 375 information

Sequence properties:

(A) length: 273 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...273

(xi) sequence representation: SEQ ID NO 375: ATGCTGACGA TTGAAACCAG TAAAAAATTT GATAAGGATC TTAAAATTCT TGTTAAAAAT 60GGGTTTGATT TAAAGCTTTT GTATAAAGTG GTTGGAAATT TAGCCACAGA GCAACCCCTA 120GAACCCAAAT ACAAAGACCA CCCACTCAAA GGCGCTTTAA AAGACTTTAG GGAATGCCAC 180CTAAAACCGG ATTTATTGCT TGTCTATCAA ATTAAAAAAC AAGAAAACAC TCTTTTTTTA 240GTAAGGCTAG GCAGTCATAG CGAGCTGTTT TGA 273(2) SEQ ID NO 376 information

Sequence properties:

(A) length: 303 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...303

(xi) sequence representation: SEQ ID NO 376: ATGCTAGAAA TTGAATTAAA AAAGAAATTC ACTAAGGATT TAAAAAAGCA TATTTTAAAT 60CAAAAAATTG AGTTAGAAGT TTTTGACTTA GTGGTTGAAA ATTTAAGAAA TCAAATTCCA 120TTGGACAAAA GATTTAAAGA CCATGCTTTA AGTGGAACAT ACAAAGGCTG TAGAGAGCGC 180CACATTAAGC CTGATGTTTT GCTTGTGTAT AGAGTGAAAG GCAATGTTTT AACTTTGGTT 240AGGCTTGGCA GTCATAGCGA GCTGTTTTGT AAACCGCCCA CACCACTCAT AACGCTTAAA 300TGA 303(2) SEQ ID NO 377 information

Sequence properties:

(A) length: 270 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...270

(xi) sequence representation: SEQ ID NO 377: TTGGTGGTTA GTGGCTCGTT GCAAAACATT GTTCGTTCTT TTTTGCGAAG GATCAGCGTT 60TTCTTCATTA TTGATTTCAT CAATTTTATT TTCGTTATTG ATCAGATCAT TCACTTCTTT 120GGTGACTTTT TCATCTTCTT CTTCATGCTC AATCTTTTTT ATATCCTTAT TAGGTTGATT 180GATTTGATTG TTTTGAGTGG TTTTAGTGTT GTTTTGGTGC GATTGGGACG ATTTTTTAGG 240CTCATCTTTG CAGGCGCTCA ACACGCTTAA 270(2) SEQ ID NO 378 information

Sequence properties:

(A) length: 1440 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1440

(xi) sequence representation: 378: ATGAAAAAAT CCCTTTGTTT GTCTTTCTTT CTGACCTTCT CTAACCCTCT TCAAGCCCTT 60GTCATTGAGC TTTTAGAAGA GATTAAAACT TCGCCGCATA AAGGCACTTT TAAGGCTAAA 120GTCCTTGATT CTAAAGAACC AAGACAAGTT TTAGGCGTTT ATAATATCTC CCCACACAAA 180AAACTCACGC TCACTATCAC TCACATATCC ACGGCAATCG TCTATCAACC CCTTGATGAA 240AAACTTTCTT TAGAAACGAC CTTAAGCCCT AACCGCCCTA CTATCCCTAG AAACACCCAA 300ATCGTTTTTT CTTCAAAAGA ATTGAAAGAA CCGCACTCAA ACCCAATACC TTCTTTAAAC 360GCGCCCATGC AAAAACCACA AAATAAACCC AGCTCATCGC AACAATCTCC TCAAAACTTT 420TCTTACCCAG AGTCCAAACT AGGCTCTAAA AACTCTAAAA ACAGCCTTTT ACAGCCTTTA 480GTAACTCCTA GCAAAGTAAG CCCCACTAAC GAAGTTAAAA CGCCAACAAA CGACGCTAAT 540CCCCCTTTAA AGCATTCTTC ACAAGATCAA GAAAACAACC TCTTTGTAGC GCCACCCACT 600GAAAAAACGC TCCCTAACAA CACCTCTAGT GCTGATGCGA GTGAAAACAA TGAAAGCAAC 660GAAAATAGGG ATAATGTGGA AAAACAAGCG ATTAGAGATC CTAATATCAA AGAATTCGCA 720TGCGGGAAGT GGGTTTATGA TGATGAAAAT TTACAAGCCT ATCGCCCAAG CATTTTAAAA 780CGCGTTGATA AAGACAAAGA GATTACAACA GACATTACCC CTTGCGATTA CAGCACCGCT 840GAAAATAAAA GCGGTAAAAT CATTACCCCC TATACTAAAA TCTCTGTTCA TAAAACAGAG 900CCTTTAGAAG ACCCTCAAAC TTTTGAAGCT AAAAATAATT TCGCCATTCT CCAAGCCAGA 960AGCTCTACAG AAAAGTGTAA AAGGGCTAGA GCGAGAAAAG ACGGCACGAC CAGGCAATGC 1020TATCTGATAG AAGAGCCTTT AAAACAAGCG TGGGAGAGCG AGTATGAAAT CACCACGCAA 1080TTAGTGAAAG CCATATATGA ACGCCCCAAA CAAGACGATC AAGTAGAGCC GACTTTTTAT 1140GAAACCAGCG AATTGGCTTA TTCTTCCACA CGAAAAAGCG AAATAACGCG TAATGAATTG 1200AATTTGAATG AAAAATTCAT GGAATTTGTG GAAGTGTATG AGGGGCATTA TTTAAACGAT 1260ATAATCAAAG AGAGCAGCGA ATACAAAGAA TGGGTTAAAA ACCATGTGCG CTTTAAAGAA 1320GGGGTGTGCA TGGCCTTAGA AATAGAAGAG CAACCACGAG CCAAAAGCAC GCCTTTGAGT 1380ATTGAAAACT CTCGTGTTGT GTGTGTCAAA AAGGGGAATT ATTTATTCAA TGAAGTTTAA 1440(2) SEQ ID NO 379 information

Sequence properties:

(A) length: 1440 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1440

(xi) sequence representation: SEQ ID NO 379: ATGAAAAAAT CCCTTTGTTT GTCTTTCTTT CTGACCTTCT CTAACCCTCT TCAAGCCCTT 60GTCATTGAGC TTTTAGAAGA GATTAAAACT TCGCCGCATA AAGGCACTTT TAAGGCTAAA 120GTCCTTGATT CTAAAGAACC AAGACAAGTT TTAGGCGTTT ATAATATCTC CCCACACAAA 180AAACTCACGC TCACTATCAC TCACATATCC ACGGCAATCG TCTATCAACC CCTTGATGAA 240AAACTTTCTT TAGAAACGAC CTTAAGCCCT AACCGCCCTA CTATCCCTAG AAACACCCAA 300ATCGTTTTTT CTTCAAAAGA ATTGAAAGAA CCGCACTCAA ACCCAATACC TTCTTTAAAC 360GCGCCCATGC AAAAACCACA AAATAAACCC AGCTCATCGC AACAATCTCC TCAAAACTTT 420TCTTACCCAG AGTCCAAACT AGGCTCTAAA AACTCTAAAA ACAGCCTTTT ACAGCCTTTA 480GTAACTCCTA GCAAAGTAAG CCCCACTAAC GAAGTTAAAA CGCCAACAAA CGACGCTAAT 540CCCCCTTTAA AGCATTCTTC ACAAGATCAA GAAAACAACC TCTTTGTAGC GCCACCCACT 600GAAAAAACGC TCCCTAACAA CACCTCTAGT GCTGATGCGA GTGAAAACAA TGAAAGCAAC 660GAAAATAGGG ATAATGTGGA AAAACAAGCG ATTAGAGATC CTAATATCAA AGAATTCGCA 720TGCGGGAAGT GGGTTTATGA TGATGAAAAT TTACAAGCCT ATCGCCCAAG CATTTTAAAA 780CGCGTTGATA AAGACAAAGA GATTACAACA GACATTACCC CTTGCGATTA CAGCACCGCT 840GAAAATAAAA GCGGTAAAAT CATTACCCCC TATACTAAAA TCTCTGTTCA TAAAACAGAG 900CCTTTAGAAG ACCCTCAAAC TTTTGAAGCT AAAAATAATT TCGCCATTCT CCAAGCCAGA 960AGCTCTACAG AAAAGTGTAA AAGGGCTAGA GCGAGAAAAG ACGGCACGAC CAGGCAATGC 1020TATCTGATAG AAGAGCCTTT AAAACAAGCG TGGGAGAGCG AGTATGAAAT CACCACGCAA 1080TTAGTGAAAG CCATATATGA ACGCCCCAAA CAAGACGATC AAGTAGAGCC GACTTTTTAT 1140GAAACCAGCG AATTGGCTTA TTCTTCCACA CGAAAAAGCG AAATAACGCG TAATGAATTG 1200AATTTGAATG AAAAATTCAT GGAATTTGTG GAAGTGTATG AGGGGCATTA TTTAAACGAT 1260ATAATCAAAG AGAGCAGCGA ATACAAAGAA TGGGTTAAAA ACCATGTGCG CTTTAAAGAA 1320GGGGTGTGCA TGGCCTTAGA AATAGAAGAG CAACCACGAG CCAAAAGCAC GCCTTTGAGT 1380ATTGAAAACT CTCGTGTTGT GTGTGTCAAA AAGGGGAATT ATTTATTCAA TGAAGTTTAA 1440(2) SEQ ID NO 380 information

Sequence properties:

(A) length: 903 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 903

(xi) sequence representation: 380 SEQ ID NO: ATGAGAAAAA CGATTTCAGC GTTGTTTTTA TCAGCGTGTA TAGGGTTATC GTCTGTTCAT 60GCGAGTAACG CTTTGATTTT ACAAACAGAT TTTAGCCTAA AAGATGGGGC CGTCTCGGCG 120ATGAAAGGCG TCGCTTTCAG CGTTGATTCT AATCTTAAAA TCTTTGATTT AACGCACGAA 180ATCCCCCCGT ATAACATTTG GGAAGGCGCT TACCGCTTGT ATCAGACCGC TAGTTATTGG 240CCAAAAGGCT CGGTATTTGT GAGCGTAGTG GATCCGGGCG TAGGCACTAA TCGTAAATCG 300GTGGTATTGA AAACTAAAAA CGGCCAGTAT TTCGTCTCTC CAGATAACGG CACGCTGACT 360TTGGTAGCGC AAACTTTGGG GATTGATAGC GTGCGTGAAA TTGATGAAAA AGCCAACCGC 420TTGAAAGGTT CTGAAAAATC CTATACTTTC CATGGCCGTG ATGTGTATGC TTACACTGGG 480GCGCGCTTGG CTTCTGGGGC GATCACATTC GAGCAGGTCG GGCCAGAGCT TCCTATAAAA 540GTTGTTGAAA TTCCTTACCA AAAAGCGAAA GCCACAAAAG GGGGAGTGAA AGGCAATATC 600CCGATTTTGG ATATTCAATA TGGCAATGTT TGGAGCAATA TCAGCGATAA ACTGCTCAAT 660CAAGCAGGGA TCAAACGAAA CGATACAGTG TGTGTAACTA TTTTTAAAAA TTCCAAGAAA 720CAATACGAAG GGAAAATGCC GTATGTCGCG AGCTTTGGCG ATGTGCCAGA AGGCCAGCCG 780TTGGTCTATT TAAACAGCTT GTTGAATGTT TCCGTGGCGT TGAATATGGA TAATTTCGCG 840CAAAAACATC AAATTAAATC TGGTGCTGAC TGGAATATTG ATATAAAGAA GTGCGCTAAA 900TAA 903(2) SEQ ID NO:381 informational

Sequence properties:

(A) length: 471 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 471

(xi) sequence representation: 381 SEQ ID NO: TTGACTAAAA AATTCATGTC TTGGATGGTG GTTATCGGGG CTTTAATTTG CGTGCTTTTA 60GGGGTGTTTA TCTTCTTCAC TAGCATGTCG GTTAAAAAAT CTTTAACCGC TTATCTTAAC 120GCTTATTTAG AGCAACGCCC AAATATCGAG GGCATGGGGA TTATAGGAGT TCCTTTTAAA 180TGCGAAAGGT TTTTTAAAAT CGCATGCGTT TCTAAAGAAC TTCGTTTTTT AGATCCTCAA 240AACTCTCCTA TTATGGATTT TAAAAATTTA AAGATCAAGC TCCATTCTTT AGATAAAAGC 300TCTCTTACCC TTTCTATCCA TTCTCAAATC CAATCCCCTA TTTTAGAACA ATCCATTCAG 360CAAAAAATCA GCCAAATCCC CTTAAAAAAC TTGAATGCCT TATTGGAAAA ATTCAAACCC 420ACGCGCTTGA ATTGCTCTTT AACATTCAAC GCTTTAGATG AAAAAACCTA A471 (2) SEQ ID NO:382 information

Sequence properties:

(A) length: 858 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 858

(xi) sequence representation: SEQ ID NO 382: ATGCAAGATT TTATTAAGAT TTTTATTCAA GAGGTTGTCT CTACTTTAGA AGGGTTAGTG 60GGTAAGGCTC CAAGCGTAGG ATTAGAAAAA GAAGTTTCTA ACAATGAAGA AGCGAGTTTA 120ATCAGCACTC CTTATGCAAG GGTTAAGATT AGCGCGATTG AAAAAAATGA AAGTCCTATT 180GAATTACTGG CTCCGGTAGA TTTAGTTACC GCTTTGAGCG ATTTGATGCT AGGAGGTGAG 240GGGGCGAGCAAGGAAGAAAT GGATAATGAC GATTTAGACG CTTTTAAAGA AATGGCTTCT 300AATATTTTTG GTGCGATCGC TACAAGCTTG AAGTCTCAAG AATTGCTCCC TAAACTCAAT 360TTCACCACCA CGAACGCTGA AATCGCTAAA GAGCTTCCTA AAAAAGAAGA TTACGCTAAG 420GCGATGGTGT TTTCTTTTAA AATGGAAGCC ATCAAAGAAA GCCAAATCGT TTTATTGATC 480ACTTCAGCGT TTGAGGGCCA ATTTGAAAAA ACGCATAAAG AAGAAAAAGA AGAAACGACA 540AAAAGCGCTA CTGAAGAGAC TAAAACCCAC GACGCGTCTT TAGAAAATAT AGAAATCCGC 600AATATCAGCA TGCTTTTAGA CGTGAAATTG AACGTTAAGG TGCGTATCGG TCAAAAAAAG 660ATGATTTTAA AAGATGTGGT CTCTATGGAT ATAGGGAGCG TGGTGGAGTT GGATCAATTG 720GTGAATGACC CTTTAGAAAT CCTCGTAGAT GACAAGGTGA TCGCTAAGGG CGAAGTGGTG 780ATCGTGGATG GGAATTTTGG CATTCAAATC ACGGATATTG GCACTAAAAA GGAACGATTA 840GAGCAACTGA AAAATTAA 858 (2) SEQ ID NO 383 information

Sequence properties:

(A) length: 990 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 990

(xi) sequence representation: SEQ ID NO 383: ATGACGACTA AAAGAGTGAA TACTGCCACA AACAAGATAA TGACATTAAA CACTTTCTTG 60GATACATGTT TTCTTTTCTT CATCAGTATT CTTTTTTACC TAAGTATACC AATTTATCCT 120AACAAAGTGG TGGTTGTCCC GCAAGGTTCG CTCAAAAAAG TGTTTTTTTC TTTGAAAGAG 180CAAGGCGTGG ATATTAACGC TTTAGATTTG CTTTTGTTGC GCCTAATGGG CATGCCTAAA 240AAAGGCTATA TTGACATGGG CGATGGGGCT TTAAGGAAGG GGGATTTTTT AGTCCGTTTG 300ATCAAAGCGA AAACGGCGCA AAAAAGCGTT ACTTTAATCC CTGGAGAAAC CCGCTATTTT 360TTCACGCAAA TTTTGAGCGA GACTTACCAA CTAGAAACAA GCGATCTCAA TGAAGCTTAT 420GAAAGCATCG CTCCACGATT AAACGGCGCT GTGATAGAAG ATGGGGTGAT ATGGCCAGAC 480ACTTATCATT TACCTTTAGG GGAGGACGCT TTTAAAATCA TGCAAACTTT GATTGGTCAA 540TCCATGAAAA AACACGAAGC CTTAAGCAAA CAATGGCTTG GATACTACCA TAAAGAAGAG 600TGGTTTGAAA AAATCATTCT CGCTTCCATT GTGCAAAAAG AAGCCGCTAA TGTTGAAGAA 660ATGCCCCTGA TTGCGAGCGT GATTTTTAAC CGCTTGAAAA AAGGCATGCC TTTACAAATG 720GATGGGGCTT TGAATTATCA GGAATTTTCA CACGCTAAAG TAACCAAAGA GCGCATTAAA 780ACCGATAACA CCCCCTACAA TACCTATAAA TTTAAGGGCT TGCCTAAAAA TCCTGTAGGG 840AGCGTGAGCT TAGAAGCGGT TAGAGCCGTG GTTTTCCCTA AAAAAACGGA TTTCTTGTAT 900TTTGTGAAAA TGCCGGATAA AAAACATGCT TTCAGCGCAA CTTATAAGGA GCATTTAAAA 960AACATTAATA TTTCTAATAA TCATTTTTAA 990(2) SEQ ID NO 384 information

Sequence properties:

(A) length: 441 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 441

(xi) sequence representation: SEQ ID NO 384: ATGAGATTGT TGTTCTTGTT ACTGAGCGCT ACTTTGATGT TACTGGCTGA AGAAAAAATA 60CCTTTAAGCG ATGACGCCCC CATTAAATTG GTTCATTGGC AAAATGCGCT AAAAGAAGTC 120CAACCCGATT CAAACGCTCC GGCAACGCCA CCTATAAAGG CCGTGCAAAC CACGCTCACT 180TTTGAAACGC CTTTTAATAA AACGCCTAAA ATCATGGAGG TTGAAGGGCA AAAAGTCATC 240GTGTTAAAAA ACGCTCAATT GGATTCTAAA AAAACGATGG ATTTTAAAGA AGCCTCTTTG 300AATGCCTTAG AAATGTTTTC CTACCAAAAT GACATCTACC TCTTGTCTAA AAAAGCTAAA 360GCGGGATTAG AAATCCAAGC TTCAAGCAGC AAGGATAAAA AGCAACTCGC TTTCTTTTTT 420TACCCAAAGG TTTTCATTTA G441 (2) SEQ ID NO 385 information

Sequence properties:

(A) length: 1983 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1983

(xi) sequence representation: 385: ATGCTAAAAA AGATTTTTTA TGGTTTTATC GTTTTATTTT TGATTATCGT AGGGTTGTTG 60GCCGTTCTTG TCGCTCAAGT TTGGGTAACT ACGGATAAGG ATATTGCTAA AATTAAAGAT 120TATCGCCCCA GTGTCGCTTC ACAGATTTTA GACAGAAAAG GGCGTTTGAT CGCTAATATT 180TATGATAAGG AATTTCGTTT TTATGCGCGT TTTGAAGAAA TCCCCCCACG ATTTGTTGAA 240AGCCTTCTAG CGGTAGAAGA CACCCTCTTT TTTGAGCATG GGGGGATCAA TTTAGACGCT 300GTCATGCGCG CTATGATTAA AAACGCTAAA AGTGGTCGTT ACACTGAAGG GGGTAGCACT 360CTAACCCAAC AACTCGTTAA AAACATGGTG CTCACACGGG AAAAAACCCT AACCAGAAAA 420CTCAAAGAAG CTATCATCTC CATACGCATT GAAAAAGTCT TAAGCAAAGA AGAAATTTTA 480GAGCGTTATT TGAACCAAAC TTTTTTTGGG CATGGGTATT ATGGCGTGAA AACCGCAAGT 540TTAGGGTATT TTAAAAAACC CCTTGACAAA CTCACGCTTA AAGAAATCAC CATGTTAGTC 600GCCTTACCTA GGGCTCCAAG TTTTTATGAC CCTACCAAAA ATTTAGAATT TTCACTCTCT 660AGGGCTAATG ATATTTTAAG GCGGTTGTAT TCTTTAGGCT GGATTTCTTC TAACGAGCTC 720AAATCCGCTC TCAATGAAGT GCCAATCGTC TATAACCAAA CTTCCACGCA AAATATCGCT 780CCCTATGTCG TGGATGAAGT GTTGAAGCAA TTGGATCAATTAGACGGGTT AAAAACTCAA 840GGCTATACCA TAAAACTCAC GATAGATTTG GATTACCAAC GCTTAGCGTT GGAGTCTTTG 900CGTTTTGGGC ATCAAAAAAT CTTAGAAAAA ATCGCTAAAG AGAAGCCAAA AACTAACGCT 960TCTAATGATA AAGATGAAGA CAACTTAAAC GCCAGCATGA TAGTTACAGA AACGAGCACC 1020GGTAAGATTT TAGCCTTAGT GGGGGGGATT GATTATAAAA AAAGCGCTTT CAATCGCGCC 1080ACGCAAGCCA AACGGCAGTT TGGGAGCGCG ATCAAGCCTT TTGTGTATCA AATCGCTTTT 1140GATAATGGCT ATTCCACCAC TTCCAAAATC CCTGATACCG CGCGAAATTT TGAAAATGGC 1200AATTATAGTA AAAACAGCGT GCAAAACCAC GCATGGCACC CTAGCAATTA TACTCGCAAA 1260TTTTTAGGGC TTGTAACCTT GCAAGAAGCC TTGAGCCATT CGTTAAATCT GGCTACGATT 1320AATTTAAGCG ATCAGCTTGG CTTTGAAAAA ATTTATCAAT CTTTAAGCGA CATGGGGTTT 1380AAAAACCTCC CTAAAGATTT GTCTATTGTG TTAGGGAGCT TTGCTATCTC ACCGATTGAT 1440GCGGCTGAAA AGTATTCTCT ATTTTCTAAT TACGGCACCA TGCTCAAACC CATGCTCATT 1500GAAAGCATCA CCAACCAACA AAACGAAGTC AAAACTTTCA CGCCCATTGA AACCAAAAAG 1560ATCACTTCCA AAGAACAAGC TTTTTTAACC CTTTCAGCGC TGATGGATGC GGTAGAAAAC 1620GGCACAGGGA GTTTGGCTCG CATTAAAGGT TTAGAAATTG CCGGTAAAAC CGGGACTTCT 1680AACAACAATA TTGACGCTTG GTTCATTGGC TTTACCCCCA CCTTACAAAG CGTGATCTGG 1740TTTGGGAGAG ACGATAACAC GCCTATTGGC AAAGGAGCGA CAGGAGGCGT TGTGAGCGCG 1800CCTGTGTATT CGTATTTCAT GCGCAATATC TTAGCGATTG AACCTTCTTT AAAAAGAAAG 1860TTTGATGTCC CCAAAGGCTT GCGTAAAGAA ATCGTGGATA AAATCCCCTA CTACTCAAGC 1920CCTAATTCCA TCACCCCCAC CCCCAAAAAA ACAGACGATA GCGAAGAACG CTTGTTGTTC 1980TAA 1983(2) SEQ ID NO:386 information

Sequence properties:

(A) length: 342 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 342

(xi) sequence representation: SEQ ID NO 386: ATGGCTAAAA TGAACGCTCC AGATGGGGTT GCCGTTTGGG TGAATGAAGA CAGGTGTAAG 60GGTTGTGATA TTTGCGTGTC GGTATGCCCG GCTGGAGTTC TTGGCATGGG GATTGAAAAA 120GAAAGGGTGC TTGGAAAAGT GGCCAAAGTA GCCTATCCAG AGAGCTGTAT TGGTTGCGTG 180CAATGCGAGT TGCACTGCCC GGATTTTGCG ATTTACGTGG CTGACAGGAA GGATTTCAAA 240TTCGCTAAAG TTTCTAAAGA AGCCCAAGAA AGAAGCGAAA AGGTTAAGGC CAATAAATAC 300ATGCTCTTAG AAGAGACTAT TTTAGAAGGG AGAGGCAAAT AA 342(2) SEQ ID NO 387 information

Sequence properties:

(A) length: 1020 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1020

(xi) sequence representation: SEQ ID NO 387: ATGATTTTCA TTGACGCATG TTTTAGAAAG GAAACGCCTT ACACACCCAT TTGGATGATG 60AGGCAAGCGG GGCGTTACCT TAGCGAATAC CAAGAGAGCC GTAAAAAAGC GGGGAGCTTC 120 39120 120TTGGAATTGT GTAAAAATAG CGATTTAGCC ACAGAAGTTA CCCTACAGCC GGTAGAGATT 180TTAGGCGTGG ATGCGGCTAT TTTGTTTAGC GATATTTTAG TAGTGCCTTT GGAAATGGGC 240TTGAATTTGG AGTTTATCCC CAAAAAGGGG CCGCATTTTT TAGAGACGAT TACGGATTTA 300AAAAGCGTGG AAAGCCTAAA AGTAGGGGTT TATAAACAAC TAAACTATGT CTATGATACG 360ATTTCTCAAA CGCGCCAAAA GCTTTCTAAA GAGAAAGCGC TAATCGGTTT TTGCGGATCG 420CCTTGGACTT TAGCGACTTA CATGATAGAA GGCGAGGGGA GCAAATCGTA TGCCAAAAGC 480AAGAAAATGC TTTATAGCGA GCCTGAAGTT TTAAAAGCGC TTTTAGAAAA GTTAAGCCTT 540GAATTGATAG AGTATTTGAG CCTTCAAATC CAAGCAGGGG TCAATGCAGT GATGATCTTT 600GACTCATGGG CTAGCGCTTT AGAAAAAGAA GCGTATTTGG AATTCAGTTG GGATTATTTG 660AAAAAAATCT CTAAAGAGCT TAAAAAACGC TATGCGCACA TCCCAGTTAT CCTTTTCCCT 720AAAGGGATTG GCGCTTATTT GGATAGCATA GATGGCGAAT TTGATGTGTT TGGCGTGGAT 780TGGGGCACGC CTTTAACTGC GGCAAAAAAG ATTTTAGGCG GTAAGTATGT TTTGCAAGGG 840AATTTAGAGC CCACCCGCCT TTATGATAAA AACGCTTTAG AAGAAGGGGT TGAAAAGATT 900 63900 900CTAAAAGTCA TGGGCAATCA AGGGCATATT TTTAATTTAG GGCATGGGAT GTTGCCGGAT 960TTGCCCAGAG AAAACGCCAA GTATTTAGTG CAATTAGTGC ATGCTAAAAC CAGGCGATAG 1020(2) SEQ ID NO 388 information

Sequence properties:

(A) length: 579 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 579

(xi) sequence representation: SEQ ID NO 388: GTGTTAGAAA AATCTTTTTT AAAAAGCAAG CAATTGGTTT TATGCGGGTT GGGTGTTTTA 60ATGTTGCAGG CTTGCACTTG CCCAAACACT TCACAAAGAA ATTCTTTTTT ACAAGATGTG 120CCTTATTGGA TGTTGCAAAA TCGCAGCCAG TATCTCACGC AAGGGGTGGA TAGCTCGCAC 180ATTGTAGATG GTAAGGCAAC TGAAGAGATA GAGAAAATCG CTACCAAAAG AGCGACAATA 240AGAGTGGCGC AAAATATCGT GCATAAACTT AAAGAAGCTT ATCTTTCTAA ATCCAACCGC 300ATCAAGCAAA AGATCACTAA TGAAATGTTT ATCCAAATGA CAAAGCCCAT TTTTGACAGC 360TTGATGAATG TGGATCGTTT AGGGATTTAT ATCAATCCTA ACAATGAAGA AGTGTTTGCG 420TTGGTGCGCG CGCGTTCCTT TGATAAGGAC GCTTTGAGCG AAGGGTTGCA TAAAATGTCT 480TTAGACGATC AAGCGGTGAG TATCCTTGTT TCTAAAGTGG AAGAAATCTT TAAAGATTCT 540ATCAATTACG GAGACGTTAA AGTCCCTATA GCCATGTAG 579(2) information SEQ ID NO 389

Sequence properties:

(A) length: 330 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 330

(xi) sequence representation: SEQ ID NO:389: ATGCTTAGAA ATCAATTTCG TATCGTGTTT GTCTCTTGTA TTGTCGCTAG CAGTTTGCAA 60: 60GCTCAAGAAA ATACCCACAC TTTGGGTAAG GTAACCACTA AGGGTGAAAG GACTTTTGAA 120TACAACAATA AAATGTATAT TGACAGGAAA GAGCTCCAAC AACGCCAAAG CAACCAAATC 180CGTGATATTT TTAGGACTAG GGCGGATGTG AATGTGGCCA GTGGGGGCTT AATGGCGCAA 240AAAATCTATG TTAGGGGGAT TGAGAGCCGT CTCTTAAGGG TAACGATAGA TGGCGTCGCT 300CAAAATGGTA ACATTTTCCA CCATGACGCT 330(2) information of SEQ ID NO:390

Sequence properties:

(A) length: 270 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 270

(xi) sequence representation: SEQ ID NO 390: GTGATGAAAA AAATCGTTGT GAGTTTATGC GTGGCGTTAG GTTTTTTAAG CGCGGATCCA 60GCGCAGGCCA ATAAAGCGAT CAGTGATGCG GATTTGATTG AAGAGATAAG GGACTTGAAA 120AAAATCATCA GCGCACAAAA CACGGAGATT AACCAATTAA GAAAAGTGCA AGAAGTCTTA 180TCTGGGCAAT TAGGGGACAT GCGTAAGGAT ATATTAAGCA CTAGAGATTA CTGTATCAGC 240TTAAGGCCTT ATATTTATAA TTGGCGCTAG 270(2) information SEQ ID NO 391

Sequence properties:

(A) length: 477 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 477

(xi) sequence representation: SEQ ID NO 391: TTGAATAAAT TTGGTTGGCG TGCGTGTTTT CTAACCCTTT TTTTTAGCGG GTATTCTAAA 60AAAGCTCCTG GAACGATAGG GAGTTTAGTG GCGTTGTTAC TGGGCTTACC TATTTTAATT 120TTTTCGGCTA ACACTTTGTT TTTAGGGGCG ATTTTTGTTG GGCTTATCGC TATTACTCAA 180ATAGATAAGG AAGAAGAAGA GACTAAGAGG CATGACAGCT CTTACATTGT GATAGACGAA 240TTAGTGGGCA TGTGGCTTGC GATGGCGATT AGCGGATTAT CGTTAGTGGG TGTGATCTTG 300AGTTTTATCT TTTTTAGGAT CTATGATATT ACTAAACCCT CACTCATTGG CAAAATAGAC 360AAAGAAGTTA AAGGGGGCTT AGGGGTTGTG GCTGATGACG CTTTAGCCGG GGTTTTAGCC 420GGATTGAGCA CGTTATTAGC CATCAATATT TTAGGATTTT TTAACATTAA GTTTTAG 447(2) SEQ ID NO 392 information

Sequence properties:

(A) length: 402 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 402

(xi) sequence representation: SEQ ID NO:392: ATGGAGTTAA TTAAGAAATT GGAAAAAGAA AGCGAAGTTT TAAAGAAAGA TTTACAACAA 60CATTCAAACG AGCTTTTTAA AATGTTGATT ATTGATAATG AAGATTTGTT TAAAGAGCAA 120TTTGAGATTA TGTTTAAAGC ATGGGTTGAA ATCGTAAAAA TGATGTTTGA ATTAACCAAA 180AAAACCAAAT TTGATGGCGA AATGATTGGC TACACAGAAG AACTTTTAAC CTTTTTAGTT 240AGAGATTTTT TTAATGGGAT TTTTAAATCC AAAGTAATAC CTAAAATGCC TATTTTTTGC 300GGTGATGTTA AATGCGAAGA TTTTAATGCC CTAAGAAGTT TAGTTTATCT TTCTGTGCTT 360GAGTTGGAAG AAACGATAAA TCCTAATAAA ATCCCATTTT AA 402(2) information of SEQ ID NO:393

Sequence properties:

(A) length: 402 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 402

(xi) sequence representation: 393 ID NO: ATGGAGTTAA TTAAGAAATT GGAAAAAGAA AGCGAAGTTT TAAAGAAAGA TTTACAACAA 60CATTCAAACG AGCTTTTTAA AATGTTGATT ATTGATAATG AAGATTTGTT TAAAGAGCAA 120TTTGAGATTA TGTTTAAAGC ATGGGTTGAA ATCGTAAAAA TGATGTTTGA ATTAACCAAA 180AAAACCAAAT TTGATGGCGA AATGATTGGC TACACAGAAG AACTTTTAAC CTTTTTAGTT 240AGAGATTTTT TTAATGGGAT TTTTAAATCC AAAGTAATAC CTAAAATGCC TATTTTTTGC 300GGTGATGTTA AATGCGAAGA TTTTAATGCC CTAAGAAGTT TAGTTTATCT TTCTGTGCTT 360GAGTTGGAAG AAACGATAAA TCCTAATAAA ATCCCATTTT AA 402(2) SEQ ID NO:394 information

Sequence properties:

(A) length: 378 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 378

(xi)sequence representation: SEQ ID NO 394: ATGAAAAAGT TAGCCGCTTT ATTTTTAGTA AGCGCGTTGG GGGTTATGAG TTTGAACGCA 60TGGGAGCAAA CCCTAAAAGC TAATGATTTG GAAGTGAAAA TCAAATCCGT GGGCAACCCC 120ATTAAAGGCG ATAACACTTT TGTGCTTAGC CCCACTTTAA AAGGTAAGGC TTTAGAAAAA 180GCTATCGTTA GGGTGCAGTT TATGATGCCT GAAATGCCCG GCATGCCAGC GATGAAAGAA 240ATGGCGCAAG TGAGTGAAAA AAACGGCCTT TATGAAGCTA AAACCAATCT TTCCATGAAC 300GGGACATGGC AGGTTAGGGT GGATATTAAA TCCAAAGAAG GCCAAGTTTA TCGCACTAAA 360ACAAGCCTGG ATTTATGA 378(2) SEQ ID NO 395 information

Sequence properties:

(A) length: 1026 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1026

(xi) sequence representation: SEQ ID NO 395: ATGAAACGGC TTTTATTGTT AGCCTTGGCC CTCTTTTTTA GCCTCTCATG CACTAACGCT 60CAAGAAATTA AAGAAACTCA AGAGACTAAA AAAACTAAAG AAACTAAAAG CCAAACCCGT 120TTTAACATTT CCACCACTAA GGTCATAGAA AAAGAATTTT CTCAAAGCCG GCGCTATTAC 180GCGCTTTTAG AGCCTAATGA AGCGCTGATT TTTTCTCAAA CCCTGCGTTT TGATGGCTAT 240GTGGAAAAGC TTTATGCGAA TAAAACCTAT ACCCCCATTA AAAAGGGCGA TAGGCTATTG 300AGCGTGTATT CCCCTGAATT AGCGGGCGTT CAAAGCGAGC TGTTATCGTC ATTGAAATTC 360AACCAGCAAG TGGGAGCGAT TAAAGAAAAA TTAAAACTAC TAGGGCTAGA AAACTTTAGC 420ATTGAAAAAA TCATCAGCAG CCATAAAGTC CAAAATGAAA TCACTATTTA CTCTCGTTTC 480AACGGCGTTA TTTTTAAAAA AAGCCCGGAT CTCAATGAGG GGAGTTTCAT TAAAAAAGGG 540CAAGAGCTTT TCAAAATCAT AGATTTAAGC CGATTGTGGG CGCTTGTTAA AGTCAATCAA 600GAGGATTTAG AATTTTTAAA AAACACGCAT CAAGCGATTT TGTTCGTAGA GGGGGTTAAA 660GGCAAGCAAG CAATCACGCT TGAAAACATC AACCCCATCA TAAATGCGCA AGATAAAATG 720CTAGAAGCGC GCTTCAATGT GCCTAATCTT AAATTGCTTT ATTACCCTAA CATGTTCGCT 780CAAGTAGAAA TCTTTCACAA ACCCCAAAAA ATGAAGATCT TGCCTAAAGA AGCGGTTTTG 840ATTAAGGGGG GGAAAGCTAT CGTGTTTAAA AAAGATGATT TTGGCTTAAG CCCGTTAGAA 900ATTAAAGCCG TCCGCTTGAG CGATGGGAGT TATGAAATTT TAGAGGGTTT AAAAGCGGGC 960GAAGAAGTCG CTAATAACGC TTTATTCGTG CTAGACGCTG ACGCTCAAAA CAATGGGGAT 1020TAT TGA 1026(2) SEQ ID NO 396 information

Sequence properties:

(A) length: 363 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 363

(xi) sequence representation: SEQ ID NO 396: ATGGGCGTAG CGGTTGTTTT ATTTTTAACG CTAATTTTAT TGTTTTTAGT TTTAAGGGAT 60TTTGGTTTAG CTAGCCCCAA ACAAAAGATT TTAGCTTTTT TAATCGTAGG GATTATAGGA 120GCGAGCATCA GCGTTTATAC TTATAAACAA AACCAACAAA ACCAACAAGA AATCGCTTTG 180CAAAGAGCGT TTTTAAGGGG GGAAACCTTG TTGTGTAAAG GCATCAAAGT CAATAACCAA 240ACCTTTAATT TAGTGAGCGG GACTTTGAGC TTTTTAGGCA AAAAACAAAC CCCTATGAAA 300GATGTTCTTG TGGATTTGGA TTCTTGTCAG ACGCTTCAAA AAGATCCCTT AATCCAACCT 360TAA 363(2) SEQ ID NO 397 information

Sequence properties:

(A) length: 999 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc-feature

(B) Position: 1 … 999

(xi) sequence representation: 397: ATGCGTTTTT TTATTTTATT TTTTATGGGT ATGCTTGGCG TTGGTTTTTC TCAAACCGAG 60TTGGATTTAA AGGATTTAGA AAAAAAGCCC GCCGGGATCG TTAGGGATTA TTATTTATGG 120CGTTATATTA GCGATAAAAA AACGAGTTTA GAAAACGCTA AAAAAGCCTA TGAATTGACT 180CAAAATAAAA ACAGCGCCCT ACAAAAAGCC ATGCAAGAAA AAGGCGTAGA AAATTCAGAT 240AAAAGCCCTG ATGCCAAAAT GCCTGAAGAT ATTTATTGCA AGCAAATTAC CTTAGAAAGC 300ATGTTAGAAA CAACAGACGC TTTCCAAGCG AGTTGTATCG CTATCGCTTT AAAATCAAAA 360ATCAGAGATT TTGATAAAAT CCCCATTCAA ACCTTTAAAC CTTTACAAGA AAAAATCAAA 420GAGGCTTACC CCATTCTTTA TGAAGAATTA GAAATCTTGC AAAGTAAGAA CGTGAGCGCT 480TCTTTGTTTA AGGCTAACGC GCAAGTGTTT AGCGCGCTCT TTAATCATTT GAGTTATGAA 540AAAAAGCTCC AAATTTTTGA AAAGCATATC CCGATTAAAG AGTTAAACCG CCTTTTAGAT 600GAAGATTACC CGGCGTTTAA CCGCTTGATC TATCAAGTCA TCTTAGATCC TAAATTGGAT 660CATTTTAAAG ACGCTCTCGC TAAAAGTAAC GCCACCCAAA GCAACGCGCA AACCTTTTTT 720ATTCTAGGAA TCAATGAAAT CTTGCACAAA AAAACTTCTA AAGCGCTCAA GTATTTTGAA 780CGCTCAGAAG CGGTTGTCAA GGACGATGAT TTTTCAAAAG ACAGAGCGAT TTTTTGGCAG 840TATTTAGCCT CTAAAAAGAA AAAAACTTTG GAGCACCTTT CACAAAGCCC AGCCCTAAAC 900 63900 900CTCTATAGTC TTTATGCGAG CCGCAAACCT CAAAACCACG CCCAGTTATC GCATCATTTC 960TCATATCCAA AATTTAAGCC AAGAGAACCC TCCTTTTAA 999(2) 398 informationof SEQ ID NO:397: ATGCGTTTTT TTATTTTATT TTTTATGGGT ATGCTTGGCG TTGGTTTTTC TCAAACCGAG

Sequence properties:

(A) length: 474 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 474

(xi) sequence representation: SEQ ID NO 398: GTGCATCTAG CCCACTACCT CAAAAGGAAT TTTTCTTTTT TCCCTAGCGT GGATATTGTG 60GATGGGGGGA CTATGGCTCA GCAACTCATT CCTTTAATCA CTTCGTATGA AAAGGTTTTG 120ATTTTAGATT GCGTGAGCGC TAAAGGCGTT GAAATTGGCT CAGTTTATGC CTTTGATTTT 180AAGGACGCTC CTAAAGAAAT CACATGGGCT GGGAGTGCGC ATGAAGTGGA AATGCTGCAC 240ACTTTAAGGC TCACGGAGTT TTTAGGGGAT TTGCCTAAAA CTTTTATCGT GGGGCTTGTG 300CCTTTTGTGA TAGGGAGCGA GACCACTTTC AAGCTTTCAA GCGAAATGTT AAACGCTTTA 360GAAACAGCCC TAAAAGCCAT AGAAACCCAA CTCAACGCAT GGGGAGTTAA AATGCAACGC 420ACCGATCATA TTGCCCTAGA TTGTATCGCT GAACTCTCTT ATAAGGGTTT TTGA 474(2) SEQ ID NO 399 information

Sequence properties:

(A) length: 924 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 924

(xi) sequence representation: SEQ ID NO 399: ATGAAAAAAG TCCTCTTACT AACTCTCTCT CTCTCTCTCT CGTTTTGGCT CCACGCTGAA 60AGGAACGGAT TTTATTTAGG TTTAAATTTT GCAGAAGGAA GCTATATTCA AGGACAAGGT 120AGCATCGGCG AAAAAGCTTC AGCAGAAAAC GCCTTAAATC AAGCGATCAA TAACGCAAAA 180AATTCATTAT TCCCTAACAC AAAAGCCATA AGAGATGTGC AAAACGCCTT AAATGCAGTG 240AAAGATTCAA ACAAAATCGC TAACCGATTC GCAGGAAATG GTGGATCGGG CGGTATTTTC 300AATGAACTCA GCTTGGGGTA TAAATATTTT TTGGGTAAAA AAAGGATTAT AGGGTTTAGG 360CACTCTCTTT TTTTCGGTTA CCAACTTGGT GGCGTTGGTT CTGTTCCTGG CAGCGGTTTA 420ATAGCTTTTT TACCCTATGG TTTCAATACG GATTTGCTCA TTAATTGGAC TAACGATAAG 480CGAGCGTCTC AAGAATACGT TGAAAGAAGG GTAAAAGGGC TCTCTATATT TTACAAAGAT 540ATGACCGGCA GAACGCTAGA CGCTGATACA TTAAAAAGAG CATCAAGGCA CATAATCAGA 600AAATCTTCAG GGCTTGTGAT TGGCATGGAA CTAGGGGCTA GCACTTGGTT TGCAAGTAAC 660AATCTCACCC CTTTTAATCA AGTCAAGAGT CGCACGATTT TTCAGTTACA AGGGAAATTT 720GGCGTTCGTT TTAGTAGTGA TGAATACGAT ATTGATCGCT ATGGCGATGA AAACTATCTT 780GGGGGTTCTA GTGTTGAATT AGGGGTTAAA GTGCCAGCGT TTAAAGTCAA TTATTATAGC 840GATGATTACG GGGATAAATT GGATTATAAA AGAGTGGTGA GCGTTTATCT TAACTATACG 900TATAACTTTA AAAACAAACA TTAA 924(2) SEQ ID NO 400 info 400

Sequence properties:

(A) length: 1737 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1737

(xi) sequence representation: SEQ ID NO 400: ATGTCAAAAA AAATCGTAGT CGATCCTATC ACTAGGATTG AGGGGCATTT AAGGATTGAG 60GTGATCGTAG ATGATGATAA TGTGATCACC GATGCGTTTT CTTCTTCTAC GCTTTTTAGG 120GGGCTAGAAA CGATCATTAA GGGCAGAGAC CCACGAGATG CAGGCTTTAT CGCTCAAAGG 180ATTTGTGGGG TATGCACTTA TTCGCATTAT AAAGCCGGTG TTACTGCGGT AGAAAACGCT 240TTAGGAATCA CTCCCCCATT AAACGCGCAA TTGGTGCGAT CTTTGATGAA CATGGCGTTG 300CTTTTTCACG ATCATGTGGT GCATTTCTAT ACTTTGCATG GGCTTGATTG GTGCGATATT 360TTGAGCACTT TAAAAGCTGA TCCCATTCAA GCAGCAAAAC TTTCTTTCAA ATACAGCCCT 420TATCCCATTA ATACCGGTGC GGGCGAATTA AAAGCGGTTC AAAAACGCTT GAATGATTTC 480GCTAAAAGCG GATCTTTAGG GCCTTTTAGC AATGGCTATT ATGGGCATAA AACCTATCGT 540TTAAACCCAG AACAAAATTT AATCGTCTTA AGCCACTACC TCAAGCTTTT AGAAATCCAA 600AGGGAAGCGG CGAAAATGAC CGCTATTTTT GGGGCCAAAC AACCTCACCC ACAAAGCCTA 660ACGGTGGGGG GTGTTACGAG TGTCATGGAT ATATTGGATC CAACAAGGTT GGCTGAATGG 720AAGAGCAAGT TTGAAGTGGT GGCTAATTTT ATCAACCATG CTTACTACCC TGATTTGGTG 780ATGGCAGGCG AAATGTTCGC TAACGAACCA TCTGTTATTA AAGGCTGTGG TTTAAGGAAT 840TTTATCGCTT ATGAAGAAGT GTTGCTTGGG AAGGATAAAT ACCTTTTGAG TAGTGGGGTG 900GTGCTTGATG GGGATATTTC TAAATTACAC CCCATTGATG AAAGTTTGAT TAAAGAAGAG 960GTTACGCATT CTTGGTATCA ATATGAAGAC ACTAAAGAAG TGCAACTCCA CCCTTATGAC 1020GGGCAAACTA ACCCGCATTA TACCGGTTTA AAAGACGGCG AGAGCGTGGG GATTGAAAAT 1080AAAATAATCC CTGCTAAAGT GCTTGACACT AAGGATAAAT ATTCTTGGAT AAAATCGCCC 1140AGATACGATA GTAAGCCCAT GGAAGTAGGG CCTTTAAGTT CCGTAGTGGT AGGTTTAGCG 1200GCGAAAAACC CTTATGTTAC TGAAGTGGCT ACTAAATTTT TAAAAGACAC GAAACTGCCT 1260TTAGAGGCGT TGTTTTCAAC GCTTGGGCGC ACAGCTGCAA GGTGTATTGA AGCTAAGACT 1320ATCGCTGATA ATGGTCTTTT GGCGTTTGAC GCGTTAGTGG AAAATCTAAA GAGCGATCAA 1380AGCACTTGTG CTCCTTATCA TATTGATAAA AATCAAGAAT ATAAAGGGCG CTACATTGGT 1440CAAGTGCCAA GGGGCATGTT AAGCCATTGG GTGCGTATTA AAAACGGCGT GGTGGAAAAT 1500TATCAAGCGG TAGTGCCTTC CACTTGGAAT GCAGGGCCTA GAGATTCTAA AAATCAAAGG 1560GGGGCTTATG AAATGAGCTT GATTGGCACT AAAATCGCTG ATTTAACCCA GCCTTTAGAA 1620ATCATTAGGA CTATCCATTC TTTTGATCCA TGCATCGCAT GCTCAGTGCA TGTGATGGAT 1680TTTAAAGGGC AGTCTTTGAA CGAGTTCAAA GTAGAGCCTA ATTTCGCTAA ATTCTAA 1737(2) SEQ ID NO 401 information

Sequence properties:

(A) length: 207 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 207

(xi) sequence representation: SEQ ID NO 401: ATGAATAGTT CTAACCTCAA AAATTGGCTA TTCCCCACTA TTTGCTTTTT TTTATTTTGT 60TATATTTTAA TTTTTTTGAT ATTTTTTATG TTTAAAAACT TGCAATCGCA ATCTTTTGGC 120TCTGTGGCAG AAACCGGAAA AAAACCCATC ACCACCACCA AGAAATTTGG TAAGGAATTG 180CAAAAACAGA TTTCAAAAAT CCATTAA 207(2) information of SEQ ID NO 402

Sequence properties:

(A) length: 162 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 162

(xi) sequence representation: SEQ ID NO 402: GTGGTCTTGC CTAAAGAAAC CTTATCTTCT ATCGCTAAAC GCTATCAAGT CAGCATTTCC 60AGTATCCAAT TAGCCAATAA CCTCAAAGAT TCTAATATCT TTATCCACCA GCGCTTAATC 120ATCCCCACTA ACAAAAAATT ACTCGCTACA AGGGAATTTT AA 162(2) SEQ ID NO 403 information

Sequence properties:

(A) length: 1059 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1059

(xi) sequence representation: SEQ ID NO 403: TTGTATTTCC TTAATGGTGG TTATAATCGG CTTCATAAAT CATACGAAAG GATTGTCATG 60CTAATCGCTC GCTTTAAAAA AGCTTTAATT TCCTATTCTT TAGGGGTTCT TCTTGTTTCA 120TCGTTATTAG GCGTGGCTAA CGCTTCTAAT CAAGAGATCC AAGTCAAGGA TTATTTTGGG 180GAGCAAACCA TAAAGCTTCC TGTTTCTAAA ATAATCTACT TGGGCAGCTT TGCAGAAGTG 240CCTGCCATGT TCAATACTTG GGATAGGGTC GTGGGCATTT CGGATTACGC TTTTAAATCT 300GATATTGTTA AAGCCACTCT CAAAGATCCT GAACGCATTA AACCCATGAG CAGTGATCAT 360GTGGCGGCGT TGAATGTGGA ATTATTAAAA AAGCTTAGCC CTGATCTTGT GGTAACCTTT 420GTGGGTAACC CTAAAGCGGT AGAGCATGCG AAAAAATTTG GGATTTCATT CCTTTCTTTC 480CAAGAAAAAA CCATTGTAGA GGTCATGGAA GATATTGACG CTCAAGCTAA GGCCTTAGAA 540GTTGACGCTT CTAAAAAATT GGCTAAAATG CAAGAAACTT TGGATTTTAT CAAAGAGCGT 600TTGAAAAATG TCAAAAAGAA AAAGGGGGTG GAGCTTTTCC ATAAAGCCAA TAAAATCAGC 660GGCCATCAAG CCCTTGATTC AGATATTTTA GAAAAAGGGG GCATAGACAA TTTTGGCTTG 720AAATACGTCA AGTTTGGGCG CGCTGACATT AGTGTGGAAA AAATCGTTAA AGAAAACCCT 780GAGATTATTT TTATTTGGTG GATAAGCCCG CTTAGCCCTG AAGACGTGTT GAACAACCCT 840AAATTTTCCA CTATCAAAGC CATTAAAAAC AAGCAAGTCT ATAAGCTCCC CACAATGGAT 900ATTGGCGGAC CTAGAGCCCC ACTCATTAGT CTTTTTATCG CTTTAAAAGC CCACCCTGAA 960GCGTTTAAGG GCGTGGATAT TAATGCGATA ATCAAAGATT ACTATAAAGT GGTCTTTGAT 1020TTGAATGACG CGGAAGTTGA ACCCTTTTTG TGGCACTGA 1059(2) SEQ ID NO 404 information

Sequence properties:

(A) length: 594 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 594

(xi) sequence representation: SEQ ID NO 404: ATGAAGTGCT CAAGCTTTAC CTCTAATAGC GTCTTAAACT TTTTTGTAGT TTTGTCTTTC 60ATCACGATAG GGCTAGTGTT TTTCTTTTTG CGTTCCCAAC CAACTAGCGT AGTTTCTAAA 120GAAAATATCC CTAAAATTGA ATTAGAAAAT TTTAAAGCGT TTCAAATCAA CGATAAAATC 180CTTGATCTGT CCATAGAGGG CAAAAAAGCC CTACAATACG ATGATCATGA AATCTTTTTT 240GATTCTAAAA TCAAGCGCTA TGATGAAGAC ACCATTGAAA GCGTTGAGTC CCCTGAAGCC 300AAACGGCAGC AGGATTTGTA TTTCTTCCCT AACGGGGTAA CTTATAAAAG AAGCGATGAT 360TCCAGTTTTT GGAGTGAAAC AGGGATTTAT AACCATAAGG AGCAAAATTT TAAAGGCAAG 420GGCCGTTTCA TTCTCACTTC AAAGGACAGC AAGGTTGAAG GGCTTGACAT TTCTTATTCG 480CATGCATTAG CTATTATTGA AGCTCAAAGC ATTCAAGCCA ATTTGTTTTT AGATGAAATC 540AAACAAAGCC AGAAAGAAAA GAAAAAATTC CCCACTTTCA AAGGAGGGTT TTAA 594(2) SEQ ID NO 405 information

Sequence properties:

(A) length: 558 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 558

The sequence expression: SEQ ID NO 405: ATGCGTTGGT GGTGTTTTTT GGTGTGTTGT TTGAGCGTTT TAAGCGTGAT GGACGCTAAA 60AAATTAGAGA ATAAAGGCTT GAAAAAAGAA AGAGAGCTTT TAGAAATTAC CGGCAACCAA 120TTTGTAGCGA ACGACAAAAC CAAAACCGCC GTTATTCAAG GCAATGTGCA GATCAAAAAA 180GGTAAAGACC GGTTGTTTGC GGATAAAGTG AGCGTGTTTT TAAACGATAA ACGAAAGCCA 240GAACGCTATG AAGCCACAGG GAACACGCAT TTTAACATCT TTACAGAAGA TAATCGTGAA 300ATCAGCGGGA GCACTGACAA GCTCATTTAT AACGCGCTGA ATGGGGAATA CAAATTATTG 360CAAAATGCGG TGGTTAGAGA AGTGGGAAAA TCTAATGTCA TCACCGGCGA TGAAATCATT 420TTAAACAAAA CCAAGGGTTA TGCTGATGTG TTGGGGAGCG CGAAGCGGCC CGCTAAATTT 480GTGTTTGATA TGGAAGACAT TAATGAAGAA AATCGTAAGG CTAAATTGAA GAAAAAAGGC 540GCTAAGGAAA AACCATGA 558 (558) (2) SEQ ID NO 406 information

Sequence properties:

(A) length: 636 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 636

(xi) sequence representation: 406: TTGATCCAAC AAAATTTTAA AACACTTAAG GAGTTGTATA TGTTAGTTAC AAAACTTGCC 60CCCGATTTTA AAGCGCCTGC CGTTTTAGGA AACAATGAGG TTGATGAACA CTTTGAGCTT 120TCTAAAAATT TAGGCAAAAA TGGTGTGATC CTTTTCTTTT GGCCAAAAGA TTTTACTTTT 180GTATGCCCTA CAGAAATCAT TGCGTTTGAC AAAAGAGTGA AAGACTTCCA CGAAAAAGGC 240TTTAATGTGA TTGGCGTGTC TATTGACAGC GAACAAGTGC ATTTCGCATG GAAAAACACC 300CCTGTGGAAA AAGGCGGTAT CGGTCAAGTG TCTTTCCCTA TGGTGGCTGA TATCACTAAG 360AGCATTTCTA GAGACTATGA TGTGCTGTTT GAAGAAGCGA TCGCTTTGAG AGGTGCTTTT 420TTGATTGATA AAAACATGAA AGTAAGACAC GCAGTGATCA ATGACTTGCC ATTAGGTAGG 480AATGCAGATG AAATGCTTCG CATGGTAGAC GCTCTCTTAC ACTTTGAAGA ACATGGTGAA 540GTATGCCCAG CAGGTTGGAG AAAAGGCGAT AAAGGCATGA AAGCAACTCA CCAAGGCGTT 600GCAGAGTATC TTAAAGAAAA TTCCATTAAG CTTTAA 636(2) SEQ ID NO 407 information

Sequence properties:

(A) length: 591 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 591

(xi) sequence representation: SEQ ID NO 407: GTGCCGTTGT GGATTATGGT AGTAGGGGCA GCTGGGATCG CTTTAGGCTT GAGCTTGTAT 60GGGCCAAAGC TCATTAAAAC GGTGGGGTCT GAAATCACAG AATTAGACAA AATGCAAGCT 120TTTTGCATCG CGCTTTCAGC GGTCATCACC GTGCTTTTAG CCTCTCAATT AGGCTTACCG 180GTAAGCTCTA CGCATATTGT GGTGGGCGCG GTGTTTGGGG TGGGCTTTTT AAGGGAGCGT 240TTGAGGGAGC AATCCAGAAG GCGTTTTGCT AGAATCAGAG ACAACATTGT AGCGGCGCAC 300 TTTGGGGAAG ATTTAGAAGA AATTGAAGGC TTTTTAGAGC GCTTTGATAA AGCCAATTTG 360AAAGAAAAAT CGCTCATGCT AGAGAGCTTG AAAAAAAGCA AGAACACCGC TATCGCTTTG 420GAATTGAAAA AGAAAGAAAA AAAGTCGCTT AAAAAAGTGT ATAAAGAAGA AGTGATCAAA 480CGCTCCATTT TGAAAAAGAT TGTTACCGCT TGGTTGGTAA CCGTGCCGGT TTCTGCGCTT 540TTAGGGGCGC TTCTTTTTGT AGCTCTTGGT TTTATAGAAA AGTATTTCTA G591 (2) information SEQ ID NO 408

Sequence properties:

(A) length: 525 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 525

(xi) sequence representation: SEQ ID NO 408: ATGTCAAATA GCATGTTGGA TAAAAATAAA GCGATTCTTA CAGGGGGTGG GGCTTTATTG 60TTAGGGCTAA TCGTGCTTTT TTATTTGGCT TATCGCCCTA AGGCTGAAGT GTTGCAAGGG 120TTTTTAGAGG CTAGGGAATA CAGCGTGAGC TCTAAAGTCC CTGGCCGCAT TGAAAAGGTG 180TTTGTTAAAA AAGGCGATCG CATTAAAAAG GGCGATTTAG TTTTTAGCAT TTCTAGCCCT 240GAATTAGAAG CCAAGCTCGC TCAAGCTGAA GCCGGGCATA AAGCCGCTAA AGCCGTTAGC 300GATGAAGTGA AAAGAGGCTC AAGAGATGAA ACGATCAATT CTGCGAGGGA CGTTTGGCAA 360GCGGCAAAAT CCCAAGCGAA TTTGGCTAAA GAGACTTATA AGCGCGTTCA AGATTTGTAT 420GACAATGGCG TGGCGAGTTT GCAAAAGCGC GATGAAGCCT ATGCGGCTAT GAAAGCACCA 480AATACAACGA GAGCGCGGCT TACCAAAAGT ATAAAATGGC TTTAG 525(2) SEQ ID NO 409 information

Sequence properties:

(A) length: 447 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 447

(xi) sequence representation: SEQ ID NO 409: ATGGAATTTT TGAGCGGGTA TTTTTTATGG GTTAAAGCTT TCCATGTGAT AGCGGTCATT 60TCGTGGATGG CAGCGTTATT TTATTTGCCA CGCCTTTTTG TCTATCATGC AGAGAACGCG 120CATAAAAAAG AGTTTGTAGG CGTGGTTCAA ATCCAAGAGA AAAAGCTCTA TTCCTTTATC 180GCTTCGCCGG CGATGGGTTT CACGCTTATT ACAGGGATTT TGATGTTGTT GATCGCCCCT 240GAAATGTTTA AAAGCGGGGG TTGGTTGCAT GCTAAATTGG CTTTAGTGGT ATTGCTTTTA 300ATCTATCATT TTTATTGCAA AAAATGCATG CGCGAGCTGG AAAAAGACCC TACAGGGAAA 360AACGCAAGGT TTTATCGTGT GTTTAATGAA ATACCCACGA TTTTAATGAT CCTTATTGTG 420ATCTTAGTGG TTGTCAAGCC TTTTTAA 447(2) SEQ ID NO 410 information

Sequence properties:

(A) length: 438 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 438

(xi) sequence representation: SEQ ID NO 410: ATGAAACCAA TTTTTTTGTT AATCTTTTTG TTGTTAGCGA GCCTTATTGC TAGAGAAAAG 60GACGCTTCTT CAAACCTTTT TGATTTGATC GATAAGGGGA TTAACAGAGA ACAAGAATTG 120AAAGAGCAGG AGCAAAAAAC GCGCTTGAAA CTGGCTCAAA GCCCTTTAGT GGCGTTAGAA 180ATTGTCCCCC AAGAAACGCC CTATTTAGAA TGGCAAGGGG CTAGGGAGTC GTATTATTTG 240AAAGTGAGCG CTGTAGTGGA GAGCGTGGTT ATTTTAAAGA TTGACATCAA TCAGGGGCGT 300TCTTGCTCGC TCTACCCCAC GCCTAAAAGC GTTTCTTTAG TGAGGAATCA AAGCGTAGCC 360TATGAAATTT TATGCGAAAA CCAGCCGCTA TGGATAGAAG TTAGCACCAA TTTAGGCAAA 420CGCACCTTTC AGTTTTAA 438(2) information SEQ ID NO 411

Sequence properties:

(A) length: 774 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule:DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 774

(xi) sequence representation: SEQ ID NO 411: ATGGCTAAGA AAAACAAACC CACCGAATGC CCCGCCGGCG AAAAATGGGC GGTTCCTTAT 60GCGGACTTTT TGTCGTTGTT GCTCGCGCTT TTTATCGCTC TTTATGCCAT TTCAGCGGTC 120AATAAATCCA AAGTGGAAGC CTTAAAAACC GAATTTATTA AGATTTTTAA TTACGCCCCA 180AAGCCAGAGG CGATGCAGCC GGTTGTAGTG ATCCCCCCTG ATTCAGGGAA AGAAGAAGAG 240CAAATGGCGA GCGAAAGCTC CAAGCCGGCT TCGCAAAATA CCGAAACAAA AGCCACTATC 300GCTCGCAAGG GCGAAGGCAG TGTTTTAGAG CAAATTGATC AAGGCTCTGT TTTAAAGCTC 360CCCTCTAGTT TGCTGTTTGA AAACGCCACT TCAGACGCTA TCAATCAAGA CATGATGCTT 420TATATTGAAC GGATCGCTAA AATCATTCAA AAACTCCCTA AAAGGGTGCA TATTAATGTG 480AGAGGTTTTA CGGATAACAC GCCTTTAAAT AAAACCCGTT TTAAAAGCCA CTATGAATTA 540GCCGCCAATC GCGCTTATAG GGTGATGAAA GTCCTTATAC AATACGGCGT GGATCCTAAC 600CAATTGTCTT TTTCTTCTTA CGGCTCTACC AACCCTATTG CGCCCAATGA TTCCCTAGAA 660AACAGAATGA AAAACAATCG TGTGGAAATC TTTTTTTCAA CCGATGCGAA CGATTTGAGC 720AAGATCCATT CTATTTTAGA TGAAGAATTC AATCCCCATA AACAGCAAGA ATGA 774(2) SEQ ID NO 412 information

Sequence properties:

(A) length: 2397 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 2397

(xi) sequence representation: 412 SEQ ID NO: ATGAGAAAGG TTATCATAAT GAATGGTTAT TTGAGGGTAA AAACCCCGTA TTTTTTAGCG 60TCGGTCGTTT TGACTTTTTG GACTTTTAAT TCTTTTATGA GCGCGAAAGA TAAGCACCAT 120TTTTTAAAAA AAGTTACAAC CACCGAGCAA AAATTCAGTT CTAGTGCCCC AATTTCATGG 180CAAAGCGAAG AGGTGCGTAA TTCCACAAGC TCTCGCACGG TGATTTCCAA CAAAGAACTC 240AAAAAAACGG GGAATTTGAA TATTGAAAAC GCCTTGCAAA ATGTGCCAGG GATTCAAATC 300AGAGACGCTA CAGGCACGGG CGTGCTGCCT AAAATTTCGG TGCGCGGTTT TGGTGGGGGC 360GGTAACGGGC ATAGCAACAC CAACATGATT TTAGTCAATG GTATCCCCAT TTATGGCGCG 420CCGTATTCCA ATATTGAACT GGCGATTTTC CCTGTAACTT TCCAGTCAGT GGATAGGATT 480GATGTGATTA AGGGGGGAAC GAGCGTCCAA TACGGCCCTA ACACTTTTGG AGGCGTGGTG 540AATGTCATCA CTAAAGAAAT CCCCAAAGAG TGGGAAAATC AAGCGGCTGA AAGGATCACT 600TTTTGGGGGC GCTCCTCTAA TGGGAATTTT GTCGATCCCA AAGAAAAAGG CAAGCCCTTA 660GCCCAAACTT TAGGAAACCA AATGCTGTTT AACACTTATG GGCGAACGGC TGGGATGTTG 720GGTAAATATA TAGGCATTAG CGCTCAAGGC AATTGGATTA ATGGGCAAGG TTTCAGGCAA 780AATAGCCCTA CAAAGGTGCA AAACTACTTG TTGGATGCGA TTTATAAGAT CAATGCGACC 840AATACTTTTA AAGCTTATTA CCAGTATTAT CAATACAACT CTTACCATCC AGGCACTTTG 900AGCGCGCAAG ATTACGCCTA TAACCGCTTC ATCAATGAGC GCCCTGACAA TCAAGATGGA 960GGGCGAGCCA AGCGCTTTGG GATCGTGTAT CAAAACTACT TTGGCGATCC GGATAGGAAA 1020GTGGGGGGCG ATTTTAAATT CACTTATTTC ACGCATGACA TGAGTAGGGA TTTTGGGTTT 1080TCCAACCAAT ACCAAAGCGT GTATATGAGC GGTCAAAATA AGATTTTACC CTTTAAAGGC 1140AAGGGAGAAA TCAGCGCAAA AAACCCTAAT TGCGGTCTGT ATTCTTATAG CGACACGAAT 1200AGCCCTTGCT GGCAATTTTT TGACAATATC CGCCGATCCG TGGTGAATGC CTTTGAGCCA 1260AAACTCAATC TTATCGTCAA TACTGGTAAA GTCAAACAAA CTTTTAACAT GGGAATGCGC 1320TTTTTAACTG AAGATTTATA CCGCCGATCC ACCACCAGGA AAAACCCTAG CATGCCTAAT 1380AATGGGAGTG GGTTTGATGC AGGAACTTCA CTCAATAATT TCAACAATTA TACCGCTGTG 1440TATGCCAGCG ATGAAATCAA TTTCAATAAC GGCATGCTAA CGATCACGCC GGGCTTGAGA 1500TACACTTTTT TAAATTACGA AAAAAAAGAC GCTCCTCCCT TTAAGGTGGG TCAAACCCCA 1560AAAACCACGA AAGAGCGTTA TAACCAATGG AATCCGGCAG TCAATGTCGG CTATAAACCC 1620ATTAAAGAAT TATTGTTTTA TTTCAATTAC CAAAGAAGCT ACATTCCGCC CCAATTCAGC 1680AATATCGGTA ATTTTGTAGG CACAAGCACG GATTATTTTC AAATCTTTAA TGTCATGGAA 1740GGCGGCTCAA GATATTATTT TAACCATCAA GTGAGTTTTA ACGCGAACTA TTTTGTGATT 1800TTTGCGAATC ATTATTTTAC CGGGCGCTAT GGGGACAACA GAGAGCCGGT CAATGCGAGA 1860TCGCAAGGCG TGGAGCTGGA ACTCTACTAC ACGCCTATTA GGGGGCTTAA TTTCCATGCG 1920GCTTACACTT TTATAGACGC TAATATCACA AGCCACACGA TGGTTACTAA CCCTGCTAAT 1980CCTAAAGGGC CTAAAAAAGA TATTTTTGGC AAAAAGCTCC CTTTTGTCAG CCCGCACCAA 2040TTCATTTTAG ACGCGAGTTA CACTTACGCT AAAACCACGA TTGGGTTAAG CTCTTTCTTT 2100TATAGCCGCG CTTATAGCGA TGTGTTAAAC ACCGTGCCTT TTACAGAATA CGCGCCCACG 2160ATTAAAAATG GGGCTATCGT TACCAAAACA GCGGGCATGA CGCCGTACTA TTGGGTGTGG 2220AATTTGCAAA TTTCTACCAC TTTGTGGGAA CGCAAAAATC AAAGCGTGAA TGCGAGCTTG 2280CAAATCAATA ACATTTTTAA CATGAAATAT TGGTTTAGCG GGATAGGCAC TAGCCCTAAC 2340GGGAAAGAAG CTGCGCCTCC CAGGAGCATC ACAGCGTATG TGAGTTATAA TTTTTAA 2397(2) SEQ ID NO 413 information

Sequence properties:

(A) length: 2397 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 2397

(xi) sequence representation: SEQ ID NO 413:ATGAGAAAGG TTATCATAAT GAATGGTTAT TTGAGGGTAA AAACCCCGTA TTTTTTAGCG 60TCGGTCGTTT TGACTTTTTG GACTTTTAAT TCTTTTATGA GCGCGAAAGA TAAGCACCAT 120TTTTTAAAAA AAGTTACAAC CACCGAGCAA AAATTCAGTT CTAGTGCCCC AATTTCATGG 180CAAAGCGAAG AGGTGCGTAA TTCCACAAGC TCTCGCACGG TGATTTCCAA CAAAGAACTC 240AAAAAAACGG GGAATTTGAA TATTGAAAAC GCCTTGCAAA ATGTGCCAGG GATTCAAATC 300AGAGACGCTA CAGGCACGGG CGTGCTGCCT AAAATTTCGG TGCGCGGTTT TGGTGGGGGC 360GGTAACGGGC ATAGCAACAC CAACATGATT TTAGTCAATG GTATCCCCAT TTATGGCGCG 420CCGTATTCCA ATATTGAACT GGCGATTTTC CCTGTAACTT TCCAGTCAGT GGATAGGATT 480GATGTGATTA AGGGGGGAAC GAGCGTCCAA TACGGCCCTA ACACTTTTGG AGGCGTGGTG 540AATGTCATCA CTAAAGAAAT CCCCAAAGAG TGGGAAAATC AAGCGGCTGA AAGGATCACT 600TTTTGGGGGC GCTCCTCTAA TGGGAATTTT GTCGATCCCA AAGAAAAAGG CAAGCCCTTA 660GCCCAAACTT TAGGAAACCA AATGCTGTTT AACACTTATG GGCGAACGGC TGGGATGTTG 720GGTAAATATA TAGGCATTAG CGCTCAAGGC AATTGGATTA ATGGGCAAGG TTTCAGGCAA 780AATAGCCCTA CAAAGGTGCA AAACTACTTG TTGGATGCGA TTTATAAGAT CAATGCGACC 840AATACTTTTA AAGCTTATTA CCAGTATTAT CAATACAACT CTTACCATCC AGGCACTTTG 900AGCGCGCAAG ATTACGCCTA TAACCGCTTC ATCAATGAGC GCCCTGACAA TCAAGATGGA 960GGGCGAGCCA AGCGCTTTGG GATCGTGTAT CAAAACTACT TTGGCGATCC GGATAGGAAA 1020GTGGGGGGCG ATTTTAAATT CACTTATTTC ACGCATGACA TGAGTAGGGA TTTTGGGTTT 1080TCCAACCAAT ACCAAAGCGT GTATATGAGC GGTCAAAATA AGATTTTACC CTTTAAAGGC 1140AAGGGAGAAA TCAGCGCAAA AAACCCTAAT TGCGGTCTGT ATTCTTATAG CGACACGAAT 1200AGCCCTTGCT GGCAATTTTT TGACAATATC CGCCGATCCG TGGTGAATGC CTTTGAGCCA 1260AAACTCAATC TTATCGTCAA TACTGGTAAA GTCAAACAAA CTTTTAACAT GGGAATGCGC 1320TTTTTAACTG AAGATTTATA CCGCCGATCC ACCACCAGGA AAAACCCTAG CATGCCTAAT 1380AATGGGAGTG GGTTTGATGC AGGAACTTCA CTCAATAATT TCAACAATTA TACCGCTGTG 1440TATGCCAGCG ATGAAATCAA TTTCAATAAC GGCATGCTAA CGATCACGCC GGGCTTGAGA 1500TACACTTTTT TAAATTACGA AAAAAAAGAC GCTCCTCCCT TTAAGGTGGG TCAAACCCCA 1560AAAACCACGA AAGAGCGTTA TAACCAATGG AATCCGGCAG TCAATGTCGG CTATAAACCC 1620ATTAAAGAAT TATTGTTTTA TTTCAATTAC CAAAGAAGCT ACATTCCGCC CCAATTCAGC 1680AATATCGGTA ATTTTGTAGG CACAAGCACG GATTATTTTC AAATCTTTAA TGTCATGGAA 1740GGCGGCTCAA GATATTATTT TAACCATCAA GTGAGTTTTA ACGCGAACTA TTTTGTGATT 1800TTTGCGAATC ATTATTTTAC CGGGCGCTAT GGGGACAACA GAGAGCCGGT CAATGCGAGA 1860TCGCAAGGCG TGGAGCTGGA ACTCTACTAC ACGCCTATTA GGGGGCTTAA TTTCCATGCG 1920GCTTACACTT TTATAGACGC TAATATCACA AGCCACACGA TGGTTACTAA CCCTGCTAAT 1980CCTAAAGGGC CTAAAAAAGA TATTTTTGGC AAAAAGCTCC CTTTTGTCAG CCCGCACCAA 2040TTCATTTTAG ACGCGAGTTA CACTTACGCT AAAACCACGA TTGGGTTAAG CTCTTTCTTT 2100TATAGCCGCG CTTATAGCGA TGTGTTAAAC ACCGTGCCTT TTACAGAATA CGCGCCCACG 2160ATTAAAAATG GGGCTATCGT TACCAAAACA GCGGGCATGA CGCCGTACTA TTGGGTGTGG 2220AATTTGCAAA TTTCTACCAC TTTGTGGGAA CGCAAAAATC AAAGCGTGAA TGCGAGCTTG 2280CAAATCAATA ACATTTTTAA CATGAAATAT TGGTTTAGCG GGATAGGCAC TAGCCCTAAC 2340GGGAAAGAAG CTGCGCCTCC CAGGAGCATC ACAGCGTATG TGAGTTATAA TTTTTAA 2397(2) SEQ ID NO 414 information

Sequence properties:

(A) length: 834 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 834

(xi) sequence representation: SEQ ID NO 414: ATGAAAACAA ACGGGCTTTT TAAAATGTGG GGGCTATTTT TAGTTTTAAT CGCTTTAGTC 60TTTAACGCAT GCTCTGATAG CCATAAAGAA AAGAAGGACG CTTTAGAAGT CATTAAACAA 120AGGGGGGTTT TAAAGGTGGG GGTTTTTAGC GATAAGCCTC CTTTTGGCTC TGTGGATTCT 180AAAGGGAACT ATCAAGGCTA TGATGTAGTC ATCGCTAAAC GCATGGCCCT TGATTTATTG 240GGCGATGAAA ATAAGATTGA GTTTATCCCT GTAGAAGCCT CAGCTAGGGT GGAATTTTTA 300AAAGCCAATAAAGTGGATAT TATCATGGCT AATTTCACGC GCACTAAAGA AAGAGAAAAA 360GTCGTGGATT TCGCTAATCC GTATATGAAA GTCGCTTTGG GGGTGATTTC TAAAGATGGG 420GTCATTAAAA ATATAGAAGA GCTGAAAGAT AAAGAGTTGA TCGTGAATAA AGGCACGACA 480GCGGATTTTT ATTTCACTAA AAATTACCCC AATATCAAAC TTTTGAAATT TGAACAAAAC 540ACAGAGACTT TTTTAGCCCT TTTAAACAAT AAGGCCATCG CATTAGCCCA TGATAACACT 600TTGTTGCTCG CTTGGGTGAA ACAACACCCT GAATTTAAAT TAGGCATTAC AAGCCTTGGC 660GATAAGGATG TGATCGCTCC AGCGATTAAA AAAGGCAACC CTAAGCTTTT AGAGTGGTTG 720AATAACGAGA TTGATTCCCT CATTTCTAGC GACTTTTTAA AAGAAGCTTA TCAAGAGACT 780TTAGAGCCTA TTTATGGCGA TGGAATCAAA CCGGAAGAAA TTATTTTTGA ATGA 834(2) SEQ ID NO 415 information

Sequence properties:

(A) length: 624 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 624

(xi) sequence representation: SEQ ID NO 415: TTGGATAATT TCATCTCACA ATACGCGCAA CGCTTGATCG TAACCAATTT GAGTCAAGCG 60ATTCGCATTT ATGGCTATGA AGTGGGTGGG ACTTTTAGAT ACAAGGGCGT GAGTTTGAAT 120GTGGGGATCT CGCGCACTTG GCCCACCACT AGGGGGTATT TAATGGCGGA CAGCTATGAG 180CTTGCCGCAA GCACCGGTAA TGTTTTTATC ATTAAATTGG ATTACACCAT TCCAAAAACA 240GGGATCAATC TTGCATGGCT TAGCCGCTTT GTTACCGGTT TGGATTATTG CGGGTTTGAT 300ATTTACTTGC CTGATTATGG GACAGCTGAA AAACCCAAAA CCCCTACCGA TTTAGCCAAA 360TGCGGATCCC AATTGGGGTT AGTGCATATG CACAAACCGG GCTATGGCGT GAGTAATTTT 420TATATCAATT GGAGCCCTAA AACCAAAAGC CACTGGAAGG GTTTGCTGCT TTCAGCCGTG 480TTTAATAATG TTTTCAACAA ATTCTATGTG GATCAAACAA GCCCCTATGT CATGAGCCCG 540GATATGCCAG GCACTGACGC TATTAAAAGA GCGATCGCAG AGCCTGGGTT TAATGCGCGT 600TTTGAAGTGG CTTACAAATG GTAG 624(2) information SEQ ID NO 416

Sequence properties:

(A) length: 735 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 735

(xi) sequence representation: SEQ ID NO 416: ATGAAAAAAG CGGGTTTTCT TTTTTTGGCG GCGATGGCTA TCATTGTTGT GAGTTTAAAC 60GCCAAAGATC CGAATGTGTT GCGTAAGATT GTTTTTGAGA AATGTTTGCC TAATTATGAG 120AAAAATCAAA ATCCTTCACC ATGCATAGAA GTCAAACCCG ACGCCGGCTA TGTGGTTTTA 180AAAGATATTA ACGGTCCGTT GCAATATTTG TTGATGCCAA CGACTCACAT TAGTGGCATT 240GAAAACCCTT TGTTGCTTGA TCCTTCTACG CCTAACTTTT TTTACTTGTC ATGGCAAGCG 300CGCGATTTTA TGAGTAAAAA ATACGGAAAA CCCATTCCTG ATTATGCGAT CTCTTTGACG 360ATCAATTCTA AAAAAGGGCG ATCGCAAAAC CATTTTCACA TCCATATTTC TTGCATTAGC 420CTTGATGTGC GCAAACAGCT GGATAATAAT CTAAAAAATA TCAACAGCCG TTGGTCGCCA 480TTATCAGGTG GCTTGAACGG GCATAAATAT TTGGCGCGTC GGGTAACAGA GAGCGAATTA 540GCGCAAAAAA GCCCGTTTGT CATGCTTGCT AAAGAAGTGC CTAACGCGCA CAAACGCATG 600GGAGACTATG GCTTGGCGGT GGTGCAACAG AGCGATAACT CCTTTGTCTT GTTAGCGACA 660CAATTTAACC CATTGACTTT AAATCGCGCT TCAGCCGAAG AGATTCAAGA TCATGAATGC 720GCGATTTTGC GTTAA 735 (2) SEQ ID NO 417 information

Sequence properties:

(A) length: 687 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 687

(xi) sequence representation: SEQ ID NO 417: ATGGTATTTG ACAGAACAAC AAGCGTAAGA GAAAAAAAAG CGGCTAAGGC GCTTGGGATT 60GTGGGGATCG TCTTTTTTAT TTTGTTTGGC ATCGTGATAA GCGGGGTGGC TTCTCAAAAA 120GAGTGGGTGC AACAATTGGA TTTATTTTTT ATAGACTTGA TCCGCAACCC TGCCCCCATT 180CAAGGGAGCA CGTGGCTTTC TTTCGTGTTT TTTAGCACTT GGTTTGCGCA AAGCAAGCTC 240ACCACTCCTA TAGCCTTACT CATTGGCTTG TGGTTTGGGT TTCAAAAACG CATCGCTTTG 300GGGGTGTGGT TTTTCTTTAG CATCTTATTA GGTGAATTCA CCTTAAAATC CCTTAAGCTT 360TTAGTGGCGC GCCCACGGCC TGTAACCAAT GGCGAATTGG TTTTTGCGCA TGGCTTTAGT 420TTCCCTAGCG GGCATGCTTT AGCTTCAGCG CTTTTTTACG GCTCTTTGGC GTTGTTGTTA 480TGCTATTCTA ACGCAAACAA TCGCATTAAA ACTATTGGTG CTATTATTTT ACTTTTTTGG 540ATTTTTTTAA TGGCGTATGA TAGGGTTTAT TTAGGGGTGC ATTACCCTAG CGATGTTTTA 600GGAGGGTTTT TATTAGGGAT TGCTTGGTCG TGCTGCTCTT TAGCGCTTTA TTTGGGGTTT 660TTGAAACGCC CTTATAAAGC CGCTTAA 687(2) SEQ ID NO 418 information

Sequence properties:

(A) length: 474 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 474

(xi) sequence representation: SEQ ID NO 418: ATGAAAAAAT TTGGTTTAGG GGTGTATTTG CTTCTTTTAG GTATTTTGGG CGGCTCTTTG 60ATCATTCTAG GAGCGATAGT CGCGCCCATT GTTTTCAAAG CTTCAAGCAT TTTACCTGAA 120TTGAATCTGA CTCCCTTTGA GAGTGGGAAA CTCATGGCGC AAATCTTTGT GCGTTTCAAT 180TATGTTTTAG GCGCGATCGG TTTTGTGGTG TTACTTTATG AAATCATTTC GTTTATCTAC 240TATAAAAGAT CGTTAGTGTA TTTGATCCTT GGCGTGGCGA TAGGGCCGTT GTGTTTGCTC 300TTTGTTTTTT ATTACACGCC TTATATTTTA AACGCTCAAA AGGTGGGTGA AGTTGCGCTT 360CAAAGTGCTG AATTTGCCCG CTCGCACCCT CAAAGCGAAT GGCTGTTTAA GGAATTGTTT 420GTGCTGGTGT GTGCTTTGTT TTTTTGGCGT TTGTTTGGGA AAAATGCGCT TTAG 474(2) SEQ ID NO 419 information

Sequence properties:

(A) length: 333 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 333

(xi) sequence representation: SEQ ID NO 419: TTGATCAATT TATTGCCCCA CCATTACCAT AAATTCCCCC CCAATATCAA CCCCTCTCTC 60ATCTCTCTAA AAGATCGCTT TTTACCCCAT GAAAAGCACA GCCAAAAGGT CAAAAAAGAA 120TGCGTCAACT TGTTTGAAGT TTTATCGCCT TTGCATAAAA TAGATGAAAA ATACCTTTTC 180CATTTAAAGA TTGCGGGGGA ATTGGCGAGC ATGGGTAAGA TTTTAAGTGT ATATTTAGCC 240CACAAGCACA GCGCGTATTT CATTTTAAAC GCTTTGAGTT ACGGCTTTAG CCACCAGGAT 300AGGGCGATCA TTTGCTTATT GGGCGCAATT TAG 333(2) SEQ ID NO 420 information

Sequence properties:

(A) length: 648 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 648

(xi) sequence representation: SEQ ID NO 420: ATGAAATCTT TTTTAAAACT TTTTGCACAG CCTTTGTTGG TGGTTTTAGC GTTCATGTTG 60TTGTATGCTT TAGCGCATGC TGTGCTTGGT TTTTACGTGA AAAAAGACAG CGCTCCAATG 120AGTCCAAATG TAGAAAAAAG CGAGACAGAG CGCCAAAACA GCACGTTTTC GCCTAAAGAA 180GAAGCCAACG CAACCACAAC CGCCACAGAA CAAAACCCCA CCAAAGACAC AGTGCCACCT 240TTAGACACAG CCACACAAAA ACAAGAGATT AAACAAGAGA TTAAACAAGA GATTAAACAA 300GAGATTAAAC AAGAGATTAA ACAAGAGATT AAACAAGAGA TTAAACAAGA AACTAAACAA 360GAGCAAGAAA AAGAAAATAA GCCTAAACAA AACAGTGTCT CGCCCGTTCA AAACGATCAA 420AAAACCCCCA CAACCCCCTT AATGGGAAAA AAACCTCTAG AGTATAAAGT CGCAGTCAGT 480GGCGTGAACG TGCGCGCTTT TCCTAGCACA AAAGGCAAAA TCATTGGCTC GCTTATAAAA 540AATAAAAGCG TGAAGGTTTT AGAAATCCAA AACGATTGGG CTGAAATTGA ATTTTCTCAC 600GAAACAAAGG GATATGTGTT TTTAAAACTT TTAAAAAAGG CTGAATGA 648(2) SEQ ID NO 421 information

Sequence properties:

(A) length: 240 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 240

(xi) sequence representation: SEQ ID NO 421: ATGTGGCCTG TGGCTCTCAA GCAGCCTAAT AGGGTGTCCC ATCATTTTTA TATCATGGCC 60ATGCTTTTTA TTTTATTTGA TGTAGAAATC GTTTTCATGT TCCCTTGGGC GATTGATTTT 120AAAAAGTTAG GCTTGTTTGG GCTCGTTGAA ATGCTAGGCT TTGTCTTCTT TTTGGCAATC 180GGTTTTATTT ACGCTTTAAA GCGAAACGCT TTGAGCTGGC AAAAATTAGA GGTGAAATAA 240(2) SEQ ID NO 422 information

Sequence properties:

(A) length: 1251 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1251

(xi) sequence representation: SEQ ID NO 422: ATGTGTGGGA TGTTTAAGAA TGAAATCAGC GCTATCCAAG GCATGATCGC TAACGCGCAA 60GAAGCTGTCG CGCAAGCCAA AATCGTTAGT GAAAACACGC AAAATCAAAA CAGCCTAGAC 120GCTGGAAAAC CATTCAACCC CTACACAGAC GCTAGTTTTG CTGAAAGCAT GCTCAAAAAC 180GCGCAAGCCC AAGCGGAGAT TTTAAACCAA GCCGAACAAG TGGTGAAAAA CTTTGAAAAA 240ATCCCTACAG CCTTTGTAAA TGACTCTTTA GGGGTGTGTT ATGAAGTGCA AGGAGGTGAG 300CGTCGTGGCA CCAATCCGGG TCAGACGACT TCTAACACTT GGGGGGCAGG CTGTGCGTAT 360GTAGGACAAA CGATAACAAA TCTTAAAAAC AGCATCGCCC ATTTTGGCAC TCAAGAGCAG 420CAGATACAGC AAGCCGAAAA CATCGCTGAC ACTCTGGTGA ATTTCAAATC TAGATACAGC 480GAATTGGGCA ACACTTATAA CAGCATCACC ACTGCGCTCT CTAATATCCC TAACGCGCAA 540AGCTTGCAAA ATGCGGTGAG TAAAAAGAAT AACCCCTATA GCCCGCAAGG CATAGACACC 600AATTACTACC TCAATCAAAA CTCTTACAAC CAAATCCAAA CCATCAACCA AGAACTCGGG 660CGTAACCCCT TTAGGAAAGT GGGGATTGTT AGTTCTCAAA CCAATAATGG CGCGATGAAT 720GGGATCGGTA TTCAGGTGGG TTACAAACAA TTCTTTGGCC AAAAAAGAAA ATGGGGCGCT 780AGGTATTACG GCTTTTTTGA TTACAACCAT GCGTTCATTA AATCCAGCTT CTTCAACTCG 840GCTTCTGACG TGTGGACTTA TGGCTTTGGA GCGGACGCTC TTTATAATTT CATCAACGAT 900AAAGCCACCA ATTTCTTAGG CAAAAACAAC AAGCTTTCTG TGGGGCTTTT TGGGGGTATT 960GCATTAGCCG GGACTTCATG GCTTAATTCT GAGTATGTGA ATTTAGCCAC CATGAATAAC 1020GTCTATAACG CTAAAATGAA CGTGGCGAAT TTCCAATTCT TATTCAACAT GGGAGTGAGG 1080ATGAATTTAG CCAGGCCTAA GAAAAAAGAC AGCGATCATG CGGCTCAGCA TGGGATTGAG 1140TTAGGGCTTA AAATCCCCAC CATCAACACG AACTACTACT CCTTTATGGG GGCTGAACTC 1200AAATACCGAA GGCTCTATAG CGTGTATTTG AATTACGTGT TCGCTTACTA A1251 (2) SEQ ID NO 423 information

Sequence properties:

(A) length: 345 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 345

(xi) sequence representation: SEQ ID NO 423: ATGGCAACCA TTCAACCATT CAACCATTCA ACCATTCAAC CATTCAACCA TTCAACCATT 60CAACCATTCA ATCATTCAAT CATTCAATCA TTCAATCATT CAACCATTCA AGCAACGCTA 120CCTTATTTTT ATAACTATTT ATCTTTTTAC AAAAACCTAT TTAAAAATCC CCTATTTTTT 180ATTATTCCCC CTTTTATTAA CCCTTTTATT AACCCTTTTA TTAACCCTTT TATTAACCCT 240TTTATTAACC CTTTTATTAA CCCTTTTATT AACCCTTTTA TTAACCCTTT TATTAACCCT 300TTTATTAACC CTTTTATTAA CCCTTTTATT AACCCTTTCA TATAA 345(2) information SEQ ID NO 424

Sequence properties:

(A) length: 381 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 381

(xi) sequence representation: SEQ ID NO 424: TTGGTTTCAG AATACTGGTT AAAATTCTTC ACGCGCTCTT TTTCTAAATC AACCATGCTC 60TTTAAAACCC TCTTGCGGTC TTTTTTCACA TTCCCTGTGG AGCTTTCAGA AAACATAACA 120TTGGGATCAA CTGTAGTGTT AATAGTAGCA GAAGCCGTTT CTGCTCTCAA CAAAAAAGTC 180GTAGCCGCTA AAAAAAATAA AATTCGCTTC ACACCAAACT CCTATATCCA TAACCGCAAC 240AAAAACAGAC GCTATTCTTC ATTAAGCCCT CTTTTAAAAT CTTCTTCTAT TTATAAAAAC 300CCACCTAGAA TTCAAGCTAT TTTGATTATC TTAAAATACA GACTTTCAAA GGGTATTTAT 360CATTTGGGTA TGATACTATA A381 (2) SEQ ID NO 425 information

Sequence properties:

(A) length: 861 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 861

(xi) sequence representation: SEQ ID NO 425: ATGAAGAAAT CTGTTATAGT AGGTGCTATC TCTCTAGCAA TGACAAGCTT ATTGTCAGCA 60GAGACCCCTA AGCAAGAAAA GGCTATTAAG ACTAGCCCTA CCAAAAAAGG TGAAAGAAAT 120GCTGCTTTTA TAGGGATTGA TTACCAGTTG GGTATGCTCA GCACTACCGC TCAAAATTGT 180TCCCATGGGA ATTGCAATGG TAATCAAAGT GGGGCTTACG GCTCTAATAC GCCTAACATG 240CCTACAGCGT CAAACCCAAC AGGAGGCCTT ACTCATGGCG CTCTAGGGAC TCGTGGGTAT 300AAAGGCTTAA GCAACCAACA ATACGCTATC AATGGTTTTG GGTTTGTTGT AGGGTATAAG 360CATTTTTTTA AGAAAGCCCC ACAATTTGGA ATGCGTTATT ACGGATTCTT TGATTTTGCA 420AGCTCTTATT ATAAGTACTA CACTTATAAT GATTATGGCA TGAGAGACGC TCGCAAGGGT 480TCTCAAAGTT TCATGTTTGG CTATGGGGCT GGCACAGATG TGTTGTTTAA CCCAGCTATT 540 TTCAATCGTG AGAACTTGCA TTTGGGGTTT TTCTTGGGCG TTGCGATTGG TGGCACCTCT 600TGGGGTCCAA CAAACTATTA TTTTAAGGAC TTAGCTGAAG AGTATAGAGG GAGTTTCCAC 660CCATCAAATT TCCAGGTCTT AGTTAATGGC GGGATCCGCT TAGGCACTAA ACACCAAGGT 720TTTGAAATTG GCTTGAAAAT CCAAACCATT CGCAATAATT ACTATACCGC TAGCGCGGAT 780AATGTGCCTG AAGGGACTAC TTATAGATTC ACTTTCCACC GCCCTTACGC CTTTTATTGG 840CGTTACATTG TAAGCTTTTA A861 (2) SEQ ID NO 426 information

Sequence properties:

(A) length: 858 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 858

(xi) sequence representation: SEQ ID NO 426: GTGAAGCGAA TTTTATTTTT TTTAGCGGCT ACGACTTTTT TGTTGAGAGC AGAAACGGCT 60TCTGCTACTA TTAACACTAC AGTTGATCCC AATGTTATGT TTTCTGAAAG CTCCACAGGG 120AATGTGAAAA AAGACCGCAA GAGGGTTTTA AAGAGCATGG TTGATTTAGA AAAAGAGCGC 180GTGAAGAATT TTAACCAGTA TTCTGAAACC AAGATGAGTA AGGGCGATTT ATCCGCTTTT 240GGAGCTTTCT TTAAGGGGAG TTTGGAAGAT TGCGTGGAGC AAAAGATTTG TTACTATGAG 300CATAGGAATG GCAAGGTTTC TTTTGTGGTG AATGACAGAG AAAAGTTTTA TAAGCATGTG 360CTTAAAGACT TAGGGACAGA GCTTTCACTC CCCTTGTTCA ACTGGCTTTA CAAAGGCTCA 420GATTTTGGGG CTTTGCATGA GCAGTTTGGG GACATGTATG ATGGGTATAT CAAATACTTG 480ATCAGCATGG TTAGGGTGAG CCAAAAAGAA AAGGCTAGAA AAGTGGATGC AATCGTTCTT 540AAAAAAATGG AAGAACAAGC TGAGAAAGAC ACTAAGGCAG CATTCCAAAA GAGGAGCAGT 600GGGGAGCTTG AAAGCCATAC TGATAGCCCT GAATTTATAA GCTCTTCTAA GACACAGAAT 660TCTTCTAACC CAGATCTAGA CCCTATGACT AACGCTAACA CGCTCAAAGA AACAGCTTCA 720AAAGAGCCAG AGACTTCTTC AAAAAAGGAA AAAAAGCCCA AGAAAAAACG ACGCCTTTCA 780AAGAAAGAAA AGCAACAACA GGCCTTACAA CAAGAGTTTG AAAAGCAAAT TAGCGACTCT 840AGTAAGTCTG AAAAATAG 858(2) SEQ ID NO 427 information

Sequence properties:

(A) length: 228 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 228

(xi) sequence representation: 427: ATGCCAAAAG AAAACACCAC CCACGAAGAC GCTTTAGCGA AATGCTTTGC GCCTGCAATT 60TTTAAAGCCA TCATGCTGAA TAAATTGATA TTGGCGGTTG TGGCTGCTCC CATTATAAAG 120ATGCTTAAAT TGAGTAAAGA GATTTGGTGG AAAAAAATGG GCAAAAAACA TGCGATAGAT 180TTTAAAATGA GGATAAAGAT ATTGGCTTCT TTAGCCCCTA GCTTTTGA 228(2) SEQ ID NO 428 message

Sequence properties:

(A) length: 405 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 405

(xi) sequence representation: SEQ ID NO 428: ATGTGCCAAA TCCAATGCTT GCTTATTTTG CTTTCTATCA ATATAGTTAG CGCGATTATC 60GTTTATTTTT TCCAAGCATT TCAAGGGGTT TTGAATTTTG AAGGGGGGTT TTTAGGGTTT 120TTTATCGTGG CGTTGTCTTC GTATTACGGC GTTAAAAAGC GTTTGGATTT GAGGAAACAA 180GATTCAAAAG AAAAAGAAGA AAAGCAAAAA TTCCAAAAAT TCGCCCTAGG TTTGGAAATG 240TCTTTCAATG TGTGGCGTTT AGGGGGGTAT GGGGTTTTAT TAGGTATTTT AGGAGTGCTT 300TTATTCTTGC ATCTTTTTAA CGGATTGCCG TTTCTTATCG GCGTGTTTGT GAGCTCGCTC 360TCTAGCGCGT TATTACGATT CTTAAACAAT AATGGTAAGT TTTGA 405(2) SEQ ID NO 429 information

Sequence properties:

(A) length: 279 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 279

(xi) sequence representation: SEQ ID NO 429: ATGGCGTGTG AATTTTTGAA AAAGCCAAAG TATTACAAGT TTATAGAGGG GGCGAATTAT 60TTGAGCTTAG GGCTTTCTAT GGTGGTGGCG ATCCTTATGG GCGTGGCTAT AGGCTATGGG 120CTTAAAAAAC TCACTCACAT TTCGTGGCTT TTTTGGCTTG GGGTTATTTG GGGCGTGTTA 180GCGAGCTTTC TCAATGTCTA TAAGGCTTAT AAAAACATGC AAAAAGACTA TGAAGAACTA 240GCCAAAGACC CTAAATACAC GCAAAATAAA ACAAAATAA 279(2) SEQ ID NO 430 information

Sequence properties:

(A) length: 240 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 240

(xi) sequence representation: SEQ ID NO 430: ATGGAAGACT TTTTGTATAA CACCTTATAT TTCATAGAGG ATTATAAGTT GGTTGTTATT 60TTTAGTTTCA TAGGGTTAAT AGCGTTATTT TTCCTCTACA AATTCATAAA AACTCAAAAA 120AAGGTTTTTA AAGATAAAGC TAACCAGCCT CAAAAGAAAA AAAGCTTTAA AGAAATCATT 180ATAGATGGGC TGAAAGAAAG GGTTAAAACC TTTGGCTTTA GGTTGCAAGC TATACTATTA 240(2) information of SEQ ID NO 431

Sequence properties:

(A) length: 1092 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1092

(xi) sequence representation: SEQ ID NO:431: ATGGCCATTG ATTTAGCAGA AGTTACAGGA GCTAAAGCCG CGCAAGAAAG GAAAAAAGAA 60CAGCCCACCA TCGCTAACGG GTTGGATAAA AACGCTTTCA TGAAACTCTT TTTAGAGCAA 120TTGAAAAATC AAGACCCCAC CGCTCCTATG GAAACGGATA AAATCATCAC CCAAACCGCG 180CAACTCACGC AAGTGGAAAT GCAAGAAGAA AACAAAAAGA CCATGCAAGA AGTCGCCAGT 240GCGATGAAAT CCAATAAAGA AACTAACGAA TCTTTAAAAG ACTTTCAAGG CGCTTTAAAA 300GACACCATGG AAAACCTGAA CAAAGGCATG GACGATAGCT TAAAGGCTAA CAACGCTTTA 360AGGGAAGTAA GCGCCCTTAA TTCTGTGAGC ATGATAGGCA AAATCGCTGA AACCGATGTG 420AGTGGGGCGA ATTTTGACGG CAACAACAAG CTTTCTTTTT CGCTCTTTTT TGATGAAAAA 480ATTGACGCTT CTAAAGGAGT GCCAGCGATT CAAATCTTAA ACGAAAACAA TGAATTGGTC 540AAAACGATTC CTTTAAAAGA TTATAACGGG CAAAAGGGGT ATATCAATTT TGAATGGGAC 600GGCACAAACG AAAAGGGCGA AAAAGTCCCT AAAGGCAATT ACAAAATCAA GGCTGAATAC 660AATTTAGACT CTCAAAGCAA GCAGTATTTG CAAACGCGCA TTGGTAGGGG CGAAGTGGAA 720AGCGTGATTT TTGATAAAGG CAAACCCATG TTAAGAATGG GCGAAATGAT TTTACCCATA 780GACAGCGCGA TAGAGTTTTA CAAACCGGAT CAAAAACCGC TTGATCAAAA ACTCTCGGAT 840CAAAAACCTC AAAAACTCTC TGAACAAAAA GCCCTTGAAC AGAAAATCTC TGAACAAAAA 900CCGCAAGAAC CCCTTGATCA AAAACTCTCG GATCAAAAAC CACAGAAACC GCTTGAACAG 960AAAATCTCTG AACAGAAACC GCTAGATCAA AAACTCTCGG ATCAAAAACC ACAGAAACCG 1020CTTGAACAGA AAATCTCTGA ACAGAAACCG CTAGATCAAA AACCCCAAAC CCCCCCTAAA 1080GAGACAGCAT GA 1092(2) SEQ ID NO:432 information.

Sequence properties:

(A) length: 654 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 654

(xi) sequence representation: SEQ ID NO 432: TTGAAACATT TAGCCCCACT CATTCATATC CCTTTTAAAG CCTTATGGCT AGGCACAGCC 60TTAAGCATGT TCTTAAGTTT GAATTTGAAC GCTGAAGAAA ACCCTACTAA AACAGAGCCT 120AAGCCCGCTA AAGGGGTTAA AAACAAGCCC AAATCGCCTG TTACTAATGT CATGATGACC 180AATTGCGATA ACCTTAAAGA CTTTAACGCT AAGCAAAAAG AAGTTTTAAA AGCCGCTTAT 240CAATTCGGAT CTAAAGAAAA TTTAGGCTAT GAAATGGCGG GCATTGCGTG GAAAGAATCA 300TGCGCAGGGA CTTATAAAAT CAATTTTTCG AATCCGAGTG CGGGCATTTA CCATGCGTAT 360ATCCCTAGCG TTTTAAAAAG CTATGGGCAT AATAATAGCC CCTTTTTGCG TAACGTGATG 420GGGGAATTGC TCATTAAAGA CGATGCGTTT GCTTCTGAAG TGGCCCTAAA AGAATTGCTA 480TATTGGAAAA CGCGCTACCA TGACAACCTA AAAGACATGA TCAAGTCTTA CAATAAGGGC 540AGTCGTTGGG AAAAAAACGA GAAAGCTAAC GCTGATGCTG AAAAATATTA TGAAGAGATA 600CAAGATAGAA TCAGGCGTTT GAAAGAATCT AAAATCTTTG AACTCGCAGT CTAG 654(2) SEQ ID NO 433 information

Sequence properties:

(A) length: 1101 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1101

(xi) sequence representation: SEQ ID NO:433: ATGCAATTTC AAAAAACCTT ACTTTCTTTA TCTTTATTAT TTTTATCTTA TTGTATCGCT 60GAAGAAAATG GGGCGTATGC GAGCGTGGGT TTTGAATATT CCATCAGTCA TGCCGTTGAA 120CACAATAACC CTTTTTTGAA TCAAGAACGC ATCCAAACGA TTTCTAACGC TCAAAACAAA 180ATCTATAAAC TCAATCAAGT CAAAAATGAA ATCACAAACA TGCCCAACAC CTTTAACTAC 240ATCAACAACG CTTTAAAAAA CAATGCTAAA TTAACCCCTA CTGAAAAGCA AGCCGAAACC 300TACTACCTGC AATCTACCCT TCAAAACATT GAAAAAATAG TCATGCTTAG CGGGGGCGTT 360GCGTCTAACC CTAAATTAGC CCAAGCGTTA GAAAAAATGC AAGAACCCAT TACTAACCCT 420TTAGAATTGG TAGAAAACTT AAAAAATTTA GAATTACAAT TCAGCCAATC TCAAAACAGC 480ATGCTTTCTT CTTTGTCTTC TCAGATCGCT CAAATTTCAA ATTCTTTGAA CGCGCTTGAT 540CCCAGCTCTT ATTCTAAAAA CGTTTCAAGC ATGTATGGGG TAGGTTTGAG CGTAGGGTAT 600AAGCATTTCT TTACCAAGAA AAAAAATCAA GGGTTTCGTT ATTACTTATT CTATGACTAT 660GGTTACACTA ATTTTGGTTT TGTGGGTAAT GGCTTTGATG GTTTAGGCAA AATGAATAAC 720CACCTCTATG GGCTTGGCAT AGATTATCTT TTCAATTTCA TTGATAATGC GCAAAAACAT 780TCGAGCGTGG GGTTTTATGT AGGCTTTGCT TTAGCGGGGA GTTCGTGGGT AGGGAGTGGT 840TTAGGCATGT GGGTGAGTCA AATGGATTTC ATCAACAACT ATTTGACGGA TTATCGGGCT 900AAAATGCACA CGAGTTTTTT CCAAATCCCT TTGAATTTTG GGGTTCGTGT GAATGTGGAT 960AGGCACAATG GCTTTGAAAT GGGCTTAAAG ATCCCTTTAG CGGTCAATTC CTTTTATGAA 1020ACGCATGGCA AAGGGTTAAA CGCTTCCCTC TTTTTCAAAC GCCTTGTCAT GTTTAACGTG 1080AGTTATGTTT ATAGTTTTTA G1101 (2) SEQ ID NO:434, information.

Sequence properties:

(A) length: 1101 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1101

(xi) sequence representation: SEQ ID NO:434: ATGCAATTTC AAAAAACCTT ACTTTCTTTA TCTTTATTAT TTTTATCTTA TTGTATCGCT 60GAAGAAAATG GGGCGTATGC GAGCGTGGGT TTTGAATATT CCATCAGTCA TGCCGTTGAA 120CACAATAACC CTTTTTTGAA TCAAGAACGC ATCCAAACGA TTTCTAACGC TCAAAACAAA 180ATCTATAAAC TCAATCAAGT CAAAAATGAA ATCACAAACA TGCCCAACAC CTTTAACTAC 240ATCAACAACG CTTTAAAAAA CAATGCTAAA TTAACCCCTA CTGAAAAGCA AGCCGAAACC 300TACTACCTGC AATCTACCCT TCAAAACATT GAAAAAATAG TCATGCTTAG CGGGGGCGTT 360GCGTCTAACC CTAAATTAGC CCAAGCGTTA GAAAAAATGC AAGAACCCAT TACTAACCCT 420TTAGAATTGG TAGAAAACTT AAAAAATTTA GAATTACAAT TCAGCCAATC TCAAAACAGC 480ATGCTTTCTT CTTTGTCTTC TCAGATCGCT CAAATTTCAA ATTCTTTGAA CGCGCTTGAT 540CCCAGCTCTT ATTCTAAAAA CGTTTCAAGC ATGTATGGGG TAGGTTTGAG CGTAGGGTAT 600AAGCATTTCT TTACCAAGAA AAAAAATCAA GGGTTTCGTT ATTACTTATT CTATGACTAT 660GGTTACACTA ATTTTGGTTT TGTGGGTAAT GGCTTTGATG GTTTAGGCAA AATGAATAAC 720CACCTCTATG GGCTTGGCAT AGATTATCTT TTCAATTTCA TTGATAATGC GCAAAAACAT 780TCGAGCGTGG GGTTTTATGT AGGCTTTGCT TTAGCGGGGA GTTCGTGGGT AGGGAGTGGT 840TTAGGCATGT GGGTGAGTCA AATGGATTTC ATCAACAACT ATTTGACGGA TTATCGGGCT 900AAAATGCACA CGAGTTTTTT CCAAATCCCT TTGAATTTTG GGGTTCGTGT GAATGTGGAT 960AGGCACAATG GCTTTGAAAT GGGCTTAAAG ATCCCTTTAG CGGTCAATTC CTTTTATGAA 1020ACGCATGGCA AAGGGTTAAA CGCTTCCCTC TTTTTCAAAC GCCTTGTCAT GTTTAACGTG 1080AGTTATGTTT ATAGTTTTTA G1101 (2) SEQ ID NO:435 information.

Sequence properties:

(A) length: 525 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 525

(xi) sequence representation: SEQ ID NO 435: TTGAATACAA TGAATAGCGT GTTAGAATGT AAAGAATTAG CGCTCTATGG AGGGAGTTTT 60GATCCTTTGC ACAAGGCTCA TTTAGCCATT ATTGAGCAAA CTTTAGAATT ATTGCCATTC 120GTTCAGCTGA TTGTCTTGCC CGCTTATCAA AACCCTTTCA AAAAGCCATG TTTTTTGGAC 180GCAAAAACCC GTTTTAAGGA ATTAGAAAGA GCTTTAAAGG GAATGCCTAG GGTGCTGTTG 240AGCGATTTTG AAATCAAGCA AGAAAGGGCT GTGCCTACGA TAGAAAGCGT TCTTCATTTC 300CAAAAACTCT ACCGCCCTAA AACGCTTTAT TTAGTCATAG GAGCGGATTG TTTGAGGCAT 360CTTTCTTCTT GGACTAACGC TAAAGAGCTT TTAAAAAGGG TGGAATTAGT GGTTTTTGAA 420AGGATTGGCT ATGAAGAAAT TCAATTTAAG GGGCGTTATC ACCCTTTAAA AGGCATTGAC 480GCGCCGATTT CTTCTAGCGC GATTAGGGCT AGTTTAGGGG TTTAA 525(2) SEQ ID NO 436 information

Sequence properties:

(A) length: 1131 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1131

(xi) sequence representation: SEQ ID NO:436: ATGAGATTTT TTTGCTTCTT TTTATTTTTT CTAACCTTTT CAAACGCGCA GATAATGATG 60ACTTTTGATT CCCAAACTAA CGCCAAACTT TCGCGCTCCA ACGAACAGCT TTCTGACATG 120CTTTACAAAC TCAATGAAAG TTTAAGAATC TATCAAAACG TGCTTTCTAA CAACCAGGAT 180CAACTTAAAG AAATCAAAAA GGCTAACAGC ACCCTAACTA GCCAAAGGCG TTTTTTTAAC 240GCTAGCCAGA TCCGCCTTAT GGACACTGAT GCACTATTGA AACAAAGCGC TTTGGAATTA 300GAAAAATTAC AAGCTTTAGA AAAACACTTA AAAGAGAGCA TGGAGCATGA ACGCTTAATC 360AAAGAATCCC AAGCGCTTTT TTTGCAAGAG CATTGCCCTT ATTTGAGCGG CGTTAAGAAT 420TTAGAAGAGG CATCAAACGC TTTAGAAGTC CAAGAAAAAA ATAACGCCCT TTTCTTACTC 480AAAGAGCCTA AACTCTTTCA TTTGCTCTCA CGATTGGATT TGATGAGCGC TTTAAACGCC 540TTATGCGATC AGGTTTTAGA AAATGAAATA CAGGATCAAC AATCCCATAA CAAAACCCTA 600GAATACAACG CCCTTATGAA CCATGATTTT CAAGCCTATA AAGCCATGCG TTTGAAAAAA 660ATTAAAAACA AGCTTCAAAC CCAAATCCAA GCTAAAGAAG ACGCCCTAAA AACCTTTTTA 720CCCCTAGAAA AACGCCTAGA AACTTTAAAA TCGCGCTTTT TATGCGACAA AGAAAATCTC 780AAATCATGCG CTAACCAATT ACAGCAACGC TACCAAAACG CCCTAATAGA GCGAGATAAG 840GAATTAAAAA ACGCTAAAAA CAACAAAGAA AAGCATGCTC TAATCTTAGC CAATTACGAA 900CACACTTTAA AAACCTTGAA TATAGAATTT TTAAGCGAAT TGAGTGAGCA AATGGCGTTT 960TTGAATGAGA CCATGGCGTT AAACGCCCAA GTTTTAGCCC TTTTAGCCCA ACAACAGACT 1020AAAAAGCCCT TCAATGTGAG CGATGGTTTG AGCGGTGGGA AAGCCCTTAT TAAAAATATC 1080CGCTTAGATC CGCATGGATT CCCTAGCTTT AAAAATTTTA AGCAAGAGTG A1131 (2) SEQ ID NO: 437.

Sequence properties:

(A) length: 690 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 690

(xi) sequence representation: 437 SEQ IDNO: GTGAAAGGCG AGAAAAACGC TTGGTATCTG GGGATTAGCT ATCAAGTCGG TCAGGCTTCA 60CAAAGCGTTA AAAACCCCCC CAAAAGCAGT GAATTTAACT ATCCTAAGTT CCCTGTGGGT 120AAAACCGACT ATCTGGCCGT TATGCAAGGC TTAGGGCTTA CTGTGGGTTA TAAGCAGTTT 180TTCGGGGAGA AAAGATGGTT TGGTGCGCGC TATTACGGCT TTATGGATTA TGGGCATGCC 240GTGTTTGGAG CGAACGCTTT GACATCAGAT AATGGTGGGG TGTGCAAACT CAATGAGCCA 300TGCGCGACCA AAGTAGGGAC TATGGGCAAT CTGTCTGACA TGTTCACTTA TGGTGTGGGT 360ATTGACACTT TATACAATGT CATTAATAAG GAAGACGCGA GTTTTGGTTT CTTTTTTGGG 420GCTCAAATCG CGGGTAACTC TTGGGGTAAT ACGACAGGGG CCTTTTTGGA AACTAAAAGC 480CCTTATAAGC ACACCTCCTA TAGCCTTGAT CCGGCGATTT TCCAGTTCCT TTTTAATTTA 540GGGATTCGCA CCCATATTGG TCAGCATCAA GAATTTGACT TTGGCGTGAA GATTCCTACT 600ATCAATGTTT ATTATTTTAA CCATGGGAAC TTGAGCTTCA CTTACCGCCG TCAATACAGC 660CTTTATGTAG GGTATCGTTA CAATTTCTGA 690(2) SEQ ID NO:438 information

Sequence properties:

(A) length: 1440 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1440

(xi) sequence representation: 438: TTGAAAAACC ACTCCTTTAA AAAAACGATC GCTCTTTCCT TGCTGGCGAG CATGTCTTTG 60TGTAACGCTG AAGAAGATGG GGCGTTTTTT GTCATTGATT ACCAAACGAG TTTGGCCAGA 120CAGGAATTGA AAAATCCAGG CTTCACTCAA GCGCAAGAAT TAAAGCAACT CATTAGAGAT 180GGGGCTGTGA GGTTGCAAAC TTCTGCCATT CCCTTATCCT ACTACTTGGA TATTTTAGGG 240AATAAAACAA AAACTCTTTT GAGTGAAAGC CTAAAAAACA ATCCGCAACA ACCAAACGGG 300CAACCCAACC AAGCTTTAGT CAATTTAGAG CAATCTCTAG GGATTTTAGG AAAACTACTA 360GATCTATCCC AACAATACGC TTCAGAAGGT GTCATTAAGC CTTTGGTGGT GGATGTAGGG 420AAAGAACAAA TCGGTATCAC GGATAGCATG CTCTTGGTGG CTCAAAACAT CGTTTTAGCT 480TTAGGGCAAG TGGATTTGAG CAAAATCCAA CAAAACAATG GTAACCAACA GCTATACGAA 540AACATCATGA AAGTCATGCT TTTAGGCACA GGCGGGACTA ATGGAGCGTA TAATGGCGTG 600AGTGTGGGCG ATATCGCCAC AGGCATGCAA AATTTTCCTT CGCAAACGGG CTTGATTGGG 660GCTAATTCTA CGGTGAGCGA GCTCAACGCT TTGATTAAGA GCGGGATTTC TTTAGATCGT 720GAAACTTTGG GGTTAGGGAG TTTTATTGAA AAAAATATCT GCAGCGGTGC ATCGTCTTGT 780TTTAGTGGGA ATCAGCTTAT CTATAAGAAA GGGCTAGACA GAACCATAAA CATCATTAAT 840GCGGTATTAG GTCAGTTTGA ATCTTCGGCT AGTTCTCTTT ATAAGATTTC TTATATCCCT 900AACCTCTTTT CGCTCAAAGA TTACCAGTCA GCGAGCATGA ACGGCTTTGG GGCTAAAATG 960GGTTATAAAC AATTTTTCAC CCATAAGAAA AATATCGGCT TAAGGTATTA TGGGTTTTTG 1020GATTATGGCT ATGCGAATTT TGGCGATACG AATTTAAAAG TGGGAGCGAA TCTTGTTACT 1080TATGGGGTAG GAACGGATTT TTTATACAAT GTGTATGAAC GCTCTAGAAG GAGAGAAAGG 1140ACTACAATCG GTCTTTTCTT TGGCGCTCAA ATTGCAGGGC AAACTTGGAG CACTAATGTA 1200ACGAACTTAT TGAGCGGGCA AAGGCCTGAT GTCAAGTCCA GTTCGTTCCA ATTCTTATTT 1260GATTTGGGCG TGCGCACCAA CTTTGCAAAA ACCAATTTCA ATAAGCACAG ATTAGACCAA 1320GGGATAGAAT TTGGGGTGAA AATCCCTGTT ATCGCTCATA AATATTTTGC AACCCAAGGC 1380TCAAGCGCGA GCTATATGAG GAATTTTAGC TTCTATGTGG GCTATTCAGT CGGTTTTTAA 1440(2) SEQ ID NO 439 information

Sequence properties:

(A) length: 540 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 540

(xi) sequence representation: SEQ ID NO 439: ATGGCGTCTC TTGCCTTTGT TCAAGCTTTT TTGGAGTCTT TTAAGGGATT TTTAAGCCAA 60GCGACCTTAA TTAGCGTTTT AATAGCGAGC GTTTTAATCC TTTTTTGCGC GATTTTGCTC 120CTTTTGGCTC TGCTTTTAAG AAACCGCTGG GCTAGTTATA TAACAACAGC AGCTTTTTTG 180GGCGCGTTTT TAAGCATGCC TTTTGTTTTG AACGTTTTAC TCACTCAAGC GATTTACCCC 240ATAGAAACGC GCATCTTGCA CGCTAATCCC TTAAGTTATA GCAACGCCTT TTCTTTGCAA 300GTGGGAGTCA AAAACATTTC CAAATTCAGT CTAAACAAAT GCGTTTTACG CCTAGAAGTC 360CTTAAAAACC CTCACAATTT TGTGGAAGAG CGAGCTTTTA AATGGTTTGT CAAAAAAAGC 420TATGAAAAAA CCTTTAAAGA AAAGATTTTG CCTGAAGAAT CCAAGGTCTT TTCATTCTTT 480 ATTGACGACT ACCCTTATTC AAAAACGGCC CCTTATCAAG TTTCTTTGTT TTGTTTGTAG 540(2) SEQ ID NO 440 information

Sequence properties:

(A) length: 390 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 390

(xi) sequence representation: SEQ ID NO 440: TTGGGGGAGT TGCTGCAAGC TAGCGCACCT TATGCGATCG CTCCTGTGGA GTTGATCGTT 60GTTTTTTATA AAAACGAATA CAAACGAAAA AAACAAACTT CTACGATGAG TAGAGAGGAA 120TTTTTACTCT ACACGAACGG GCTTTGGAAT TTTAGCGGTG AATCCAAAAA GCGCCTAAAG 180CACCCAGCCC CATTCCCAAG GGAATTACCC AGGCGTTGCA TCCAATTGTT TTCTTTTTTG 240GAAGACACGA TTTTTGATCC CTTTAGCGGC TCTGGCACGA CTATTTTAGA GGCCAACGCT 300TTAGGGCGTT TTAGCGTGGG TTTAGAGATT GAAAAAGAAT ATTGCGAGTT GTCTAAAAAG 360CGTATTTTAG AGAGTTTGTC GTTAGTGTGA 390(2) SEQ ID NO 441 information

Sequence properties:

(A) length: 984 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 984

(xi) sequence representation: SEQ ID NO 441: GTGCTTAAGG GGTTAAAAAA AGCGTTTAAG GAGAGGTTTT GCTCTCAAGT GTATATCTCT 60TTTAATGTGG ATCACAATCT TTTATCCGCT CAAGTTTTAA GGGTTAAAAA CCACCGCATC 120AAAGAGAAAT TTTTTAAAAC TTTTGAGACT AAAGTGGAAA CTAAAAATGG TGAAGTCCCC 180ATTCAAGCCT TAAAAATCGC CAGAACTTAT AGCCAAAAAT ACCCCTACAC CTATTTTAGC 240GCGATGAGTA AAGCTAAAGA GGTTTTATGC GAAAAGCAGG CGTTTGAACA AATCAAACAA 300GAAAATCAAG ATTATCAGGC TTGTGAAGTC AATCAAAAGT ATTGCGTTTA TGTGGAATCT 360AAGGATTTTC TAAAGGATTT CAAGCGTTTT AAAATCCAGG ATGTGGATTT TTTGTTTTCG 420CCCTTTAGCC TTATTTATGA TTTTGTGCGC GATAATTTAG AAAACAAGCC GTTGTTGTAT 480CTGCTTTTAG AGCGTTCAAG GTTTTATTTT TTGATTGCGG ATAAAAAAGA GATTTTTTTA 540GCCAAATCCG TGTTTTTAGA AGAGCAACCT GAAGAGTTTA TAGAGAGCAA AGAAGAAGAT 600TCTATGGGAA TGGATAATGA AGCTGTGGAT TTGTTTTTGA GTGAAATCCA AGAAGATATT 660GACAGCCTTG AAGAAGCGAT AGGCCTAGAC AGCAGCAAGG ATAATAGCGA AAAAATAACA 720GAGGACGCTT ATAGTTTGAT TGAAGGCATG ACGAATATCC CCTTGATTGC AGATGTTTTG 780CAAGAGGGAT TGCGTGGCGT CTATCATTCT AGAGAGATAG ACTTTGTAGA AAAAGTGGTT 840GTTTTAGACA GCTGTCAAAT CCACCACAAG GCGTTAATGC ATTTGCAAGA AACTTTGATG 900ATAGAAGTGG ATAGGCTCGA TTTTTCTTTA GTGGAGCGGT TGAATGTTTT AGCGCGCATG 960GAGAATGAAA AGCATGCGTT TTAG 984(2) SEQ ID NO 442 information

Sequence properties:

(A) length: 1296 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1296

(xi) sequence representation: SEQ ID NO 442: ATGAATATTC AAACAAAGAA AAGATTTTTA GCAAATTTAT TGCTTTTTAG CCTGTTTTCT 60TGCCTTAAGG CTGAAACCCT TTCAGAAGAC CATCAAATCC TGTTGAGTTC AGACGCTTTC 120CATAGAGGGG ATTTTGCCAC CGCTCAAAAA GGCTATATGA ATCTCTATAA GCAAACCAAT 180AAAGTGGTGT ATGCTAAAGA GGCGGCCATT TCAGCGGCGA GTTTAGGGGA CATTAAAACC 240GCTATGCATT TAGCCATGCT TTATCAAAAA ATCACCAATA ATCGTAACGA TGTTTCTATC 300AATAAGATTT TAGTGGATGG CTATGCACAA ATGGGGCAGA TTGATAAGGC GATTGAACTA 360TTACACAAGA TTCGTAAGGA AGAAAAAACC ATAGCCACAG ACAATGTGTT AGGGACTTTG 420TATTTGACTC AAAAGCGTTT GGATAAGGCT TTCCCGTTGT TGAATAAGTT TTATAACCAA 480GTGCATGATG AAGACAGCCT AGAAAAACTC ATTACGATCT ATTTTTTACA AAACCGCAAA 540AAAGAGGGTT TGGATCTGTT GCAATCTCAT ATAGACAGGT ATGGTTGCTC AGAGCAATTG 600TGCCAAAAAG CGCTCAACAC CTTCACGCAA TTTAACGAGC TTGATTTGGC TAAAACGACT 660TTCGCTCGTT TGTATGAAAA AAACCCTATT GTTCAAAACG CCCAATTTTA CATAGGGGTA 720TTAATCTTGT TAAAAGAGTT TGATAAGGCC CAGCAAATCG CAGAATTATT CCCCTTTGAC 780AGGCGTTTGT TGCTAGACTT ATACACCGCG CAAAAAAAAT TTGATCAAGC TTCCAAACAG 840GCTTCTTTAA TCTATCAAGA AAGAAAAGAC CCTAAATTCT TAGGCTTAGA GGCGATTTAT 900CATTATGAAA GCTTGAGCGC GAATAAGAAA AAGCTCACCA AAGAAGAGAT GTTGCCCATC 960ATTCAAAAAT TAGAGCAAGC CACCAAAGAG CGCCAAGCAT GGCTTGCTAA AACTAAAGAT 1020AAAGAAGACG CGCAAGACGC TTTCTTTTAT AATTTTTTAG GGTATTCCTT AATAGATTAT 1080GACATGGATG TTAAAAGGGG CATGGATCTT GTGAGGAAAG CCTTAGCGTT AGATTCTAAC 1140TCAGTGCTTT ATTTGGATTC TTTAGCATGG GGTTATTACA AATTAGGGAA TTGTTTCGAG 1200GCTAAAAAAA TCTTTTCTAG CATCGCTAAA GAGCTTATCC AAAACGAACC CGAATTGAAA 1260GAACACAATA AAATCATTCA AGAATGCAAG AAATAG 1296(2) SEQ ID NO 443 information

Sequence properties:

(A) length: 1245 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1245

(xi) sequence representation: SEQ ID NO 443: TTGATTCAAA AGAACAAGAG CTTATCAATC TTTTTAATCT CAAATTCGGT CGTTTTTCTT 60GGGAAAATTA TCTTGCATAA AGTTTTTATC ATGGAAGCTT TGGAGTGTTT GAAAAGAATA 120GAAAAAGAAA GCATCCAAAC AATCTATATA GACCCCCCTT ATAACACCAA GAGTTCTAAC 180TTTGAATATG AAGACGCTCA TGCTGACTAT GAAAAATGGA TTGAAGAACA TTTGATTTTA 240GCAAAAGCTG TGTTAAAACA AAGTGGTTGT ATTTTTATTT CTATGGACGA TAATAAAATG 300GCTGAAGTTAAAATCATTGC CAATGAAATT TTTGGAACGC GCAATTTTTT AGGCACTTTT 360ATCACCAAAC AAGCCACAAG ATCTAACGCT AAACACATCA ATATTACTCA TGAATATGTT 420TTAAGCTACG CTAAAAATAA AGCGTTCGCT CCTGGTTTTA AAATCTTACG AACGCTTTTG 480CCCATTTATG CTAAAGCATT AAAAGATTTA ATGCGAACGA TTAAGAATGT TTTTAAACAA 540AAAGGACAAG CTCAAGCCCA ACTTATTTTA AAAGAACAAA TCAAAGAGTT ATCCCAAAAA 600GAACATTTTA ATTTTTTAAA AAATTATAAT TTAGTGGATG AAAAAGGTGA GATCTATTTC 660GCTAAAGATT TATCCACGCC TTCAAACCCG CGCAGTGTAG CGATACAAGA AATCAATCTT 720TTTTTAGAAC CCTTAAAAAG CAGAGGGTGG AGCAGCGATG AAAAGCTTAA GGAGTTATAT 780TATCAAAATA GACTTATTTT TAAGAATAAT CGCCCTTATG AAAAATATTA CCTAAAAGAA 840TCGCAAGATA ATTGTTTGAG CGTGTTAGAT TTTTATAGCC GACAAGGCAC AAAAGATTTA 900GAAAAATTAG GCTTAAAGGG GCTTTTTAAA ACGCCAAAAC CTGTAGCATT GATTAAATAT 960TTATTATTAT GCTCCACCCC TAAAGATTCT ATTATTTTAG ATTTTTTTGC AGGCAGCGGG 1020ACAACAGCGC AAGCGGTTAT AGAAGTTAAT AAGGATTATT ATTTGAATTG GTCTTTTTAT 1080TTGTGCCAAA AAGAAGAAAA AATTAAAAAT AACCCGCAAG CTGTTAGCAT TTTAAAAAAC 1140AAGGGGTATA AAAACACGAT TTCAGACATC ATGCTGTTGC GTTTAGAAAA GATCATCAAA 1200AGAAGTGAAT ACGAAATTTT AAAAACAAAA TCTATTTTAT TTTAA 1245(2) SEQ ID NO 444: 444,444,32,3532,3245,1140 Information

Sequence properties:

(A) length: 501 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 501

(xi) sequence representation: SEQ ID NO 444: TTGGAGATTG ATAAAACAGA ATGCTCTACT CTTTTAGCAA GCATTCAAAA ACAACAGCTT 60GTGATACCCG TTGTGGGGAA TTTTAGCGCA GGCAAAAGCA CGCTATTAAA CCGCTTTTTA 120GGCAGTAGCG TTTTGCCTAC CGGTATCACG CCAGAGACTT CTTTAGCCAC TGAATTGCAC 180TATAGCGCTA ATGAACGCAT AGAGGCTTTT TCAAGCAATG ACGAAAAAAC AGAGAGTTTT 240GAACTGAATG AGCAAAGTTT TGAGGCGATT AAAGAGAATG CGGCGAAGTA TTCCTACCTT 300AAGGTTTATT TGAATAATGA AGCCTTAAAA GATAGTGCGC CTTTAGTGTT TGTGGATATG 360CCCGGGTTTG ATAGCCCCAT TTCAAGCCAC ACCCATGCCA TTTTGGAATA TTTGGAAAGG 420GGCGTGCATT TTGTCATTCT CACAAGCGTA GAAGAGGGTA ACCTCACTAA ACGCATGGTT 480AGGGAGTTAA AAACCTTTTA G501 (2) SEQ ID NO 445 information

Sequence properties:

(A) length: 756 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 756

(xi) sequence representation: SEQ ID NO 445: ATGAAACTCC CGGTCGTTGA GAGCTTTTTT TCCTTACAGG GTGAAGGAAA AAGGATAGGC 60AAGCCCAGTC TTTTTTTGCG CTTAGGGGGG TGTAACCTTT CATGCAAGGG CTTTAATTGT 120AAAACCTTAT TCAATGATGA AATCCTAACA GGTTGCGATA GTTTGTATGC GGTGCATCCT 180AAATTCAAAA CATCTTGGGA TTATTACAAT GAGCCTAAGC CCTTGATTGA ACGATTAGTT 240AATTTAGCCC CTAATTATAA GGATTTTGAT TTCATTCTTA CAGGCGGGGA GCCAAGCTTG 300TATTTTAATA ACCCTATTTT ATTGAGCGTT TTAGAGCATT TTTACCATAA AAAAATCCCT 360TTATTTGTAG AGAGTAATGG CTCTATTTTT TTTGAATTTA GCCCTATTTT AAAAGAATTG 420CATTTCACCC TAAGCGTCAA ACTCTCTTTT TCTTTGGAGC AAGAAAGCAA GCGGATCAAC 480CTTAAAGCCT TACAAAATAT CTTAAATAAC GCTAAAAGCG TGCATTTTAA ATTCGTATTG 540GAGAGTCAAA ACGCCGCTCA TTCTATCGCA GAAATTCAAA GCCTTTTGAA ACAGCTCTCC 600TTAAAAAATA ATGAAATCTT TTTAATGCCC CTAGGCACAA CTAACAACGA GCTAGACAAA 660AATCTAAAAA CCCTAGCCCC CCTAGCCATA GAGCATGGTT TTAGGCTGAG CGATAGGCTT 720CATATCCGCT TGTGGGACAA TAAGAAAGGG TTTTAA 756(2) SEQ ID NO 446 information

Sequence properties:

(A) length: 1146 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1146

(xi) sequence representation: SEQ ID NO:446: ATGAATTTAA ACTTTATGCC CCTATTGCAT GCTTATAACC ATGTAAGCAT TGATTTTCAT 60TTCAATTCTA GCGCTAGGGA TTTTTGCGTG CATGAAGTGC CTTTGTATGA ATTTAGCAAC 120ACGGGCGAAC ATGCCGTTAT TCAAGTGAGA AAAAGCGGTT TAAGCACTTT AGAAATGCTT 180CAAATTTTTT CTCAAATTTT AGGGGTAAAA ATCGCTGAAT TGGGTTATGC GGGCTTGAAA 240GATAAAAACG CGCTGACGAC TCAATTCATC TCACTCCCTA AAAAATACGC CCCTTTATTA 300GAAAAAAATA CGAGCAACTT TCAAGAAAGA AACCTTAAAA TCCTGTCTTT GAATTACCAT 360CACAATAAAA TCAAATTAGG GCATTTAAAG GGGAATCGCT TTTTTATGCG TTTCAAAAAA 420ATGACCCCCC TAAACGCTCA AAAAACGGAG CAAGTTTTAG AACAAATCGC GCAGTTTGGC 480ATGCCTAATT ATTTTGGCTC GCAACGCTTC GGGAAGTTCA ATGACAACCA TAAAGAGGGG 540TTAAAAATCT TGCAAAATGA AACGAAATTC GCCCACCAAA AATTAAACGC TTTTTTAATT 600TCAAGCTATC AAAGTTATTT GTTTAATTCG CTTTTAAGCA AGCGATTAGA AATCAGTAAA 660ATCATTAGCG CTTTTAGCGT CAAAGAAAGT TTAGAATTTT TTAAACAAAA AAATTTAAGC 720GTCCATTCAA ACGCCCTAAA AGCCCTTAAA AACCAAGCCC ACCCCTTTAA AATCTTAGAA 780GGCGATGTGA TGCGCCATTA CCCTTATGGG AAGTTTTTTG ACGCTTTGGA ATTAGAAAAA 840GAGAGCGAAA GGTTTTTGAA CAAAGAAGCT GTGCCTACGG GGTTACTGGA CGGTAAAAAA 900GCTCTTTATG CAAAAAATTT GAGTTTAGAA ATTGAAAAAG GATTCCAGCA TAACCTTTTA 960AGTGGCCATG CTAAAACGCT AGGATCCAGG CGGTTTTTTT GGGTGTTTGT GGAAAATATA 1020ACTTCTCAAT ACATCAAAGA AAAAGCGCAA TTTGAATTGG AATTTTACTT GCCTAAAGGG 1080AGTTATGCGA GCGCGCTGCT CAAAGAAATC AAGCATGAGA AAGGAGAAAA TAATGACGAA 1140TTTTGA 1146(2) SEQ ID NO:447 information.

Sequence properties:

(A) length: 2094 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 2094

(xi) sequence representation: SEQ ID NO 447: TTGCAAAACT TTGTTTTTAA TAAAAAATGG CTCATCTATT CTAGCCTACT CCCCTTATTT 60TTTCTTAACC CTTTAATGGC AGAAGACGAT GGGTTTTTTA TGGGGGTGAG TTATCAAACT 120TCTTTGGCCG TTCAAAGGGT GGATAACTCA GGGCTTAACG CCAGTCAAGA CGCATCCACT 180TATATCCGCC AAAACGCTAT CGCTCTAGAA TCTGCGGCGG TGCCTTTAGC CTATTATTTA 240GAAGCGATGG GCCAACAAAC GAGAGTCTTA ATGCAAATGC TCTGCCCTGA TCCTTCTAAA 300AGATGTTTGC TCTATGCAGG GGGCTATCAA AACGGACAAA ATAATAACGG CGATACAGGC 360AACAACCCCC CAAGAGGCAA TGTCAATGCC ACCTTTGATA TGCAATCTCT AGTCAATAAT 420TTAAACAAGC TCACCCAACT CATCGGCGAG ACTTTAATCC GTAACCCTGA AAATCTTCCT 480AACTCCAAAG TCTTTAACGT CAAATTTGGC AATCAAAGCA CTGTTATTGC ATTGCCTGAG 540GGTCTAGCCA ATACCATGGA CGCTTTAAAC AATGACATCA CCAACGCTTT AACCACGCTC 600TGGTATAACC AAACCTTAAC GAATAAATCT TTTAGCACCC CTAGTAACAC TTCTGTGAAT 660TTTAGCCCCC AAGTCTTGCA ACACCTTTTA CAAGACGGCT TAGCCACAGC AAATAATAAT 720CAAACCATTT GCAGCACTCA AAACCAATGC ACCGCCACTA ATGAAGCTAA ATCTATCGCT 780CAAAACGCCC AAAACATCTT CCAGGCTTTA ATGCAAGCAG GGATTTTAGG GGGCTTAGCC 840AATGAAAAGC AATTTGGCTT CACTTACAAC AAAGCCCCCA ATGGCAGCGA TTCCCAACAA 900GGCTATCAAA GCTTTAGCGG CCCGGGTTAT TACACCAAAA ACGACAACAC CACGCAAGCG 960CCCTTAAAAG CATTACCCGC TGGAGCGACA ATTGGATCAG GCAATGGCCA ATACACCTAC 1020CACCCCAGCT CGGCAGTCTA TTATTTAGCC GATAGCATCA TCGCTAATGG CATCACCGCT 1080TCTATGATTT TTTCAGGCAT GCAAAATTTC GCCAATAAAG CCGCTAAACT GATAGGCACT 1140TCAAGCTATA ACCAGATGCA AGATGTGATC AATTACGGGG AAAGCTTGCT TAGTAACACC 1200GTAGCGTATG GGGATTTCAT CACCAATTGG GTCGCCCCCT ATTTGGATTT AAACAATAAA 1260GGTTTGAATT TCTTGCCTAA TTATGGGGGG CAATTGAATG GCGCTAATAA TCAAACCCCA 1320CAATTAACCC CACAACAAGC CCAACAAGAA CAAAAAGTGA TCATGAACCA ATTAGAGCAA 1380GCCACAAACG CCCCCACCCC CGCGCAAATA AACAGGATTT TAGCCAACCC CTATTCCCCC 1440ACGGCAAAAA CTTTAATGGC TTATGGGCTC TATCGCTCTA AAGCAGTGAT TGGCGGAGTG 1500ATTGATGAAA TGCAAACTAA AGTGAATCAA GTCTATCAAA TGGGCTTTGC TAGGAATTTT 1560TTGGAGCATA ACTCTAATTC TAATAACATG AACGGCTTTG GCGTGAAAAT GGGCTATAAG 1620CAATTTTTCG GCAAAAAGCG CATGTTTGGG CTTAGGTATT ATGGTTTTTA TGATTTTGGT 1680TACGCTCAAT TTGGCACAGA ATCTTCTTTA GTGAAAGCCA CCCTCTCTAG CTATGGAGCG 1740GGCACAGACT TTCTTTATAA TGTTTTTACC CGAAAAAGAG GGACTGAAGC GATAGATATA 1800GGTTTTTTTG CCGGTATCCA ACTTGCAGGG CAAACCTGGA AAACGAATTT TTTAGATCAA 1860GTGGATGGCA ACCATCTTAA ACCTAAGGAC ACTTCTTTCC AATTCCTTTT TGATTTGGGC 1920ATAAGGACCA ATTTTTCCAA AATCGCTCAT CAAAAAAGAT CTCGTTTTTC TCAAGGGATA 1980GAATTTGGCC TTAAAATACC GGTGCTTTAT CACACCTACT ACCAATCAGA AGGCGTTACA 2040GCGAAGTATA GAAGAGCCTT TAGTTTTTAT GTGGGCTACA ACATAGGCTT TTGA 2094(2) SEQ ID NO 448 information

Sequence properties:

(A) length: 2094 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 2094

(xi) sequence representation: SEQ ID NO 448: TTGCAAAACT TTGTTTTTAA TAAAAAATGG CTCATCTATT CTAGCCTACT CCCCTTATTT 60TTTCTTAACC CTTTAATGGC AGAAGACGAT GGGTTTTTTA TGGGGGTGAG TTATCAAACT 120TCTTTGGCCG TTCAAAGGGT GGATAACTCA GGGCTTAACG CCAGTCAAGA CGCATCCACT 180TATATCCGCC AAAACGCTAT CGCTCTAGAA TCTGCGGCGG TGCCTTTAGC CTATTATTTA 240GAAGCGATGG GCCAACAAAC GAGAGTCTTA ATGCAAATGC TCTGCCCTGA TCCTTCTAAA 300AGATGTTTGC TCTATGCAGG GGGCTATCAA AACGGACAAA ATAATAACGG CGATACAGGC 360AACAACCCCC CAAGAGGCAA TGTCAATGCC ACCTTTGATA TGCAATCTCT AGTCAATAAT 420TTAAACAAGC TCACCCAACT CATCGGCGAG ACTTTAATCC GTAACCCTGA AAATCTTCCT 480AACTCCAAAG TCTTTAACGT CAAATTTGGC AATCAAAGCA CTGTTATTGC ATTGCCTGAG 540GGTCTAGCCA ATACCATGGA CGCTTTAAAC AATGACATCA CCAACGCTTT AACCACGCTC 600TGGTATAACC AAACCTTAAC GAATAAATCT TTTAGCACCC CTAGTAACAC TTCTGTGAAT 660TTTAGCCCCC AAGTCTTGCA ACACCTTTTA CAAGACGGCT TAGCCACAGC AAATAATAAT 720CAAACCATTT GCAGCACTCA AAACCAATGC ACCGCCACTA ATGAAGCTAA ATCTATCGCT 780CAAAACGCCC AAAACATCTT CCAGGCTTTA ATGCAAGCAG GGATTTTAGG GGGCTTAGCC 840AATGAAAAGC AATTTGGCTT CACTTACAAC AAAGCCCCCA ATGGCAGCGA TTCCCAACAA 900GGCTATCAAA GCTTTAGCGG CCCGGGTTAT TACACCAAAA ACGACAACAC CACGCAAGCG 960CCCTTAAAAG CATTACCCGC TGGAGCGACA ATTGGATCAG GCAATGGCCA ATACACCTAC 1020CACCCCAGCT CGGCAGTCTA TTATTTAGCC GATAGCATCA TCGCTAATGG CATCACCGCT 1080TCTATGATTT TTTCAGGCAT GCAAAATTTC GCCAATAAAG CCGCTAAACT GATAGGCACT 1140TCAAGCTATA ACCAGATGCA AGATGTGATC AATTACGGGG AAAGCTTGCT TAGTAACACC 1200GTAGCGTATG GGGATTTCAT CACCAATTGG GTCGCCCCCT ATTTGGATTT AAACAATAAA 1260GGTTTGAATT TCTTGCCTAA TTATGGGGGG CAATTGAATG GCGCTAATAA TCAAACCCCA 1320CAATTAACCC CACAACAAGC CCAACAAGAA CAAAAAGTGA TCATGAACCA ATTAGAGCAA 1380GCCACAAACG CCCCCACCCC CGCGCAAATA AACAGGATTT TAGCCAACCC CTATTCCCCC 1440ACGGCAAAAA CTTTAATGGC TTATGGGCTC TATCGCTCTA AAGCAGTGAT TGGCGGAGTG 1500ATTGATGAAA TGCAAACTAA AGTGAATCAA GTCTATCAAA TGGGCTTTGC TAGGAATTTT 1560TTGGAGCATA ACTCTAATTC TAATAACATG AACGGCTTTG GCGTGAAAAT GGGCTATAAG 1620CAATTTTTCG GCAAAAAGCG CATGTTTGGG CTTAGGTATT ATGGTTTTTA TGATTTTGGT 1680TACGCTCAAT TTGGCACAGA ATCTTCTTTA GTGAAAGCCA CCCTCTCTAG CTATGGAGCG 1740GGCACAGACT TTCTTTATAA TGTTTTTACC CGAAAAAGAG GGACTGAAGC GATAGATATA 1800GGTTTTTTTG CCGGTATCCA ACTTGCAGGG CAAACCTGGA AAACGAATTT TTTAGATCAA 1860GTGGATGGCA ACCATCTTAA ACCTAAGGAC ACTTCTTTCC AATTCCTTTT TGATTTGGGC 1920ATAAGGACCA ATTTTTCCAA AATCGCTCAT CAAAAAAGAT CTCGTTTTTC TCAAGGGATA 1980GAATTTGGCC TTAAAATACC GGTGCTTTAT CACACCTACT ACCAATCAGA AGGCGTTACA 2040GCGAAGTATA GAAGAGCCTT TAGTTTTTAT GTGGGCTACA ACATAGGCTT TTGA 2094(2) SEQ ID NO 449 information

Sequence properties:

(A) length: 3714 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc_ feature

(B) Position: 1 … 3714

(xi) sequence representation: 449 SEQ ID NO ATGATAAAAA AAGCTAAAAA ATTTATACCA CTCTTTTTAA TTGGCTCCCT CTTAGCTGAA 60GACAATGGCT GGTATATGTC TGTAGGCTAT CAAATCGGTG GCACGCAGCA ATTCATCAAT 120AACAAACAAC TTTTAGAAAA TCAAAATATC ATCAATAGCA TCACCCAAAG CGCGATCAAT 180ATTGCAGGGC CTACTACCGG CCTAATCACT TTAAGCTCTC AAAGCGTTAT TGACGCTTTA 240GGCTATGGCG TGAGTAACAC CGTGGGTAAC CAATTAGAAG GCATTTCTAA TATCCTGAAT 300CAAATTGGCA AAAGAAAAGA CTTTTATTCT AGCCGTCAAA TCTCTAGCAT TTCCCAGCAA 360ATCATAGGGC TTAAAGGAAG CTCTGATCCC TTAAAAGCCC ATTCTTCACA AATCACAGCC 420AAACTCCTTT CCAACACCCA AAGCGCGTTT GATCAGGGCA TCGCTCTAAG CTCTAATATC 480ATTAGTGCAG TCAATAGCCT AAACCCTAGC AACAACTCCC AAGAAGTCAA AGCCCAGCTC 540CAAAACACCG CGCAATCCAT GACAGAATTG TTGCAACAAA TTGAACACAG CATCACTAAA 600ACCACTAGCA CCACTTACGC ACAATCCTTA CTCTCCAATC TGACCGATGC GGTGAATGCA 660TCTAGCAATA ATACCACTTA TGTGAGCGCT CTTGTTAACG CTTTAAACAC TTTAGGGGTG 720GGGGTTTTCC CCACCACAAC CTCAACGCAT GTGGTGCTAA ACCCACCGGG ACAAGTCGTA 780TTCTATCCAA CTAATTCCCT TTTAGGCTCT ACTTCTTCAA ACAGCAATAA CCAACAACAA 840TACAACAACA CCCTTTTAAT GAACACCTTA CAAGGGGAAT TAAGCACTAA CAATCAAAAT 900 63900 900AACCCCAATG GTTGCGCCAA TCAAATCCAG TGTTTAGAGC AATTCATCCA AAATTTAACC 960CCTTTAGCCG CAACCCCCAC TTCAACTAAC CAGGCCAACC AGCAAGTCCA AGCCATCGCT 1020CAAAAACTTC AAAGCGTTGC TATCAACGCT TTAGACAACA ATGCGATCAA CAACACCACC 1080TATAATTTAA ACAACTTGCA CAACGCTTTG AATTTCCAAG CCTATCAAAG CACGATAGAA 1140CAATACAATA ACGCTTTAAA GCAAATTTCG TGGATTAGTT TTAGCGAGCC TAAAAACTTG 1200CTCAAAAACA CTTCCAATAA CTACCAAATC GGCACGGTTA CCAACGATCA AGGGCAAAAT 1260ATCAGCGCCT ATGATTGCAC AAGCGCTACC GGAAGCCTTT CTAGCGATGC TTCTAGTGGG 1320ATTTCATGCT CAGCCACAAG CTCCACAAAT AACACAAATA GTTTTGACAA TTCTTTAGTC 1380GCTACCTCCA AAGTCCAAAC CATCAACGGC AAAGAGCAGA TCGGCGTGAA TTCTTTTAAT 1440CTTGTCTCTC AAGTGTGGAG CGTTTATAAC TCTTTAAAAA CTTCAGAAGA AAATTTGCAA 1500AAAAACGCCA AAATATTATG CAACAATGGA TCCCAATCTG GGACAAGCCC ATGCAATAGC 1560TCTTCAGGGG GTTTGAGCAT CAGCGGGAAC GCCCAATTGC AAAATATTTT AAGCCCTACT 1620AATGGGACTA CCACTAATAC TCAAGCTAAA AGCAACGCTT CCAAACTAAA AGCGATGGTA 1680ATGGTGAATA ATGAAGAAGA AGCCAAAACG ACCAATTTCA ATCAAAGCAG TGGGCCAACC 1740ACACAATCTT CTAACAGCAC GGTGATGGGA GCTTTAAACA CCGTATTGCA AAATGTCAGC 1800AATTTCCAAC AAAGCATTCA AAGCGCTTTT CAAAACCAAG AAAATAATAT CCAAGCTTGG 1860GCGAACGCAC TTTATAACAC TAGTAACCCT AATGGGAATC AATCGCAAAA TTTAACCACT 1920AACAATAACC AAGATTTACG CATCCAATTA AGGGCGAATT TTTACCAGCT CATCAATACC 1980ATTAACCAGC AAGTGCCTAC AGACATGAAC GCTTTAATTA ATCAAAGCCA ACAAACCCAG 2040CAAACAAGCG GATCAGCAAG CACCACGAAC AACGCATGCG CGAGCGGAAT GGGGAGTAGT 2100GGCAACTGGT GCTACCAGCA GTGGTCCGAT TCTAAGGCTT ATTACAGCGG GTTGCAAAGC 2160GCTTTAGGGT ATCAAACACA AGCGACAACT CAAAATGGGA GCAGTGGTGG GAGCAATATC 2220ACCTACAATG TCCAACAAAT CACGCTCACT AGCGGTGGTT TGCTCAATCA AATTATCACA 2280AACCTTAAGA GCGTTAATGG GGGCAGTAAT GGGGGAAGCA GTGGGAATGG CACTAGTCAA 2340ATCAACACAG CCTACCAAAT GCTCACAGAC GCTAGCGATG GGAAATTAGG GACTTATAAT 00 2400AGTAGCAATA GTAGCAATAG TAGCAATAGT GGCAATAATA ACGGCTATAC GCCATGCAAT 2460 2520AACGCCACCA CCGCAACCAC CACGACCGAC AGCAATTTAC AAAAAGTCTA TAATGACGCC 2580CAAAAAATAG CCAATATTAT CGCCAGCTCT GGGAACAATA AAGGCGTTGA AAACGGCTTA 2640AAACAATTCT TTGAAGCGTT AAAAAGTAAT AGCAGCAGTC TTAGTAATTT ATGTGGTAAT 2700GGTAGTAGCG GTAGTAGCTC TACTTGCTCC GGTGGGCTTA TCAACCTTTT AGGGGCAATC 2760CCCACAAACG GAGTGAGCGA TACGAATAAT TTAATTAATC TGCTCACTGA ATTCATTAAA 2820ACCGCCGGGT TTATCCAAAA TAATGATAGT AATGTATCTA CTAGTCTTAC AAGCGCTTTT 2880CAAGCCATTA CGAGCGCTAT TTCTCAACCG TTTCAAGCCT TGCAAAACGA TATTAGCCCT 2940AATGCGATTT TGACCTTGCT CCAAGAAATC ACTTCTAACA CCACCACCAT TCAGTCATTC 3000TCGCAAACCT TACGGCAGCT TTTAGGGGAT AAAACCTTCT TTATGGTGCA ACAAAAGCTC 3060ATTGATGCGA TGATTAACGC CAGAAATCAG GTTCAAAACG CGCAAAATCA AGCCAATAAC 3120TACGGCTCTC AACCCGTTTT AAGCCAGTAT GCGGCCGGTA AAAGCACCCA ACACGGCATG 3180AGCAATGGCT TAGGGGTTGG CATAGGCTAT AAATACTTCT TTGGTAAGGC TAGGAAATTA 3240GGCCTTAGGC ATTATTTTTT CTTTGATTAC GGCTTTAGTG AAATAGGCCT AGCCAATCAA 3300AGCGTGAAAG CGAATATCTT TGCTTATGGG GTAGGCACGG ATTTTTTATG GAATCTATTC 3360AGGAGGACTT ACAACACTAA AGCGTTGAAT TTTGGGCTAT TTGCCGGGGT CCAACTGGGC 3420GGTGCAACTT GGCTTAGTTC CTTAAGGCAA CAAATCATTG ACAACTGGGG GAACGCTAAT 3480GACATCCATT CAACGAATTT TCAAGTGGCG CTGAATTTTG GGGTGCGCAC CAATTTCGCG 3540GAGTTTAAGC GTTTTGCTAA GAAATTCCAC AATCAAGGGG TCATCAGCCA AAAGAGCGTG 3600GAATTTGGGA TCAAGGTGCC TCTCATCAAT CAAGCGTATT TGAATAGTGC TGGGGCTGAT 3660GTGAGCTACA GGAGGCTTTA TACTTTCTAT ATCAATTACA TCATGGGGTT TTAA 3714(2) SEQ ID NO 450 information

Sequence properties:

(A) length: 516 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 516

(xi) sequence representation: SEQ ID NO 450: ATGGAAAAAT TACCTAAAAA ACGAGTTTCT AAAACCAAAT CACAAAAACT TATCCATAGC 60CTAACCACCC AAAAAAACAG AGCCTTTCTC CAAAAAACCA GCGCCAATGA AATGCTTTTA 120GAGTTAGAAA AAGCGGCGTT TAAAAAAAAT GAAGCCTATT TTATTTCTGA TGAAGAAGAT 180AAAAATTACG TTTTAGTGCC GGACAATGTG ATCTCTCTTT TGGCAGAAAA CGCCAGAAAG 240GCTTTTGAAG CCAGGCTTAG GGCGGAATTA GAAAGGGATA TTATCACCCA AGCGCCGATT 300GATTTTGAAG ACGTGCGCGA AGTTTCTTTG CAATTGTTAG AAAATTTACG CCAAAAAGAC 360GGGAATTTGC CCAATATCAA CACCTTAAAT TTTGTCAAAC AAATCAAAAA AGAACACCCT 420AATTTATTCT TTAATTTTGA CAACATGTTC AAACAACCCC CTTTTAATGA GAATAATTTT 480GAAAATTTTG ACAATAGCGA TGAGGAAAAT TTTTAA 516(2) SEQ ID NO 451 information

Sequence properties:

(A) length: 1308 basepairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1308

(xi) sequence representation: SEQ ID NO 451: ATGAAAAAAA TTTTAATCAC TTTAATCACT TTATTATTAG GAGTTTTTAT GGGGTTACAA 60GCGAGTGCTT TGACACACCA AGAAATCAAT CAAGCTAAAG TCCCTGTGAT TTATGAAGAA 120AACCATTTGT TACCCATGGG GTTTATCCAT TTAGCCTTTA GAGGGGGTGG GAGCTTGAGC 180GATAAAAACC AGTTGGGTTT GGCGAAATTG TTCGCGCAAG TTTTAAACGA AGGCACTAAA 240GAGCTTGGCG CGGTGGGGTT TGCGCAACTT TTAGAGCAAA AAGCGATCAG TTTGAATGTG 300GATACCAGCG CAGAAGATTT GCAAATCACT TTAGAATTTT TAAAAGAATA CGAAGATGAA 360GCCATAATGC GCTTAAAAGA GCTTTTAAAA TCCCCTAATT TCACGCAAAA CGCTTTAGAA 420AAAGTCAAAA CCAGAATGTT AGCCCAACTT TTACAAAAAG AAAGCGACTT TGATTATTTG 480GCTAAACTGA CTTTAAAACA AGAGCTTTTT GCTAACACCC CTTTAGCTAA TGCGGCCTTA 540GGCACTAAAG AGAGTCTTCA AAAAATCAAG CTAGACGATT TGAAACAGCA ATTTGCTAAG 600GTTTTTGAAC TCAATAAACT CGTGGTGGTG CTTGGGGGCG ATTTGAAAGT CAATCAAACG 660CTCAATCGTT TAAATAACGC CCTCAATTTC TTGCCGCAAG GTAAAGCCTA TGAAGAGCCT 720TATTTTGAAG CGAGCGATAA AAAAAGTGAA AAAGTCCTCT ATAAAGACAC TGAGCAGGCT 780TTCGTGTATT TTGGCGTGCC CTTTAAAATC AAGGATCTAA AACAGGATTT AGCGAAATCT 840AAAGTCATGA TGTTTGTGCT TGGGGGGGGG TTTGGCTCTC GTTTGATGGA AAAAATCAGG 900GTTCAAGAGG GCTTGGCTTA TAGCGTGTAT ATCCGCTCCA ACTTTTCTAA AGTGGCGCAT 960TTTGCGAGCG GGTATTTGCA AACCAAGCTC AGCACTCAAG CTAAAAGCGT TGCCTTAGTT 1020AAAAAAATAA TTAAAGAATT TATAGAAAAA GGCATGACGC AACAAGAATTAGACGACGCT 1080AAAAAGTTTT TACTAGGCTC TGAGCCTTTA AGGAATGAAA CGATCTCAAG CCGCTTGAAC 1140ACCACTTACA ATTATTTTTA TTTGGGTTTG CCTTTAGATT TCAACCAAAC GCTACTCAAT 1200CAAATCCAAA AAATGAGTTT GAAAGAGATC AATGATTTCA TTAAAGAGCA TACCGAAATC 1260AACGACTTGA CCTTTGCTAT TGTGAGCAAT AAAAAGAAGG ACAATAA 1308(2) SEQ ID NO 452 information

Sequence properties:

(A) length: 1845 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1845

(xi) sequence representation: SEQ ID NO 452: TTGGCTTCTC CAAAAGAAAC CCCAAAAGAG GCTCAAAAAA ATGAAGCTCA AAACGAAACC 60TCTCAATCCA ATCAAACGCC TAAAGAAATG AAAGTCAAGT CCATTTCTTA TGTCGGGCTT 120TCTTACATGT CTGACATGCT CGCTAATGAA ATTGCAAAGA TTCGCGTGGG CGATATGGTG 180GATTCTAAAA AAATAGACAC CGCTGTTTTA GCTTTGTTCA ACCAAGGGTA TTTTAAAGAC 240GTTTATGCCA CTTTTGAAAA CGGCATTTTA GAGTTTCATT TTGATGAAAA AGCCAGGATT 300GCCGGGGTAG AAATCAAGGG TTATGGGACT GAAAAGGAAA AAGACGGCTT AAAATCCCAA 360ATGGGGATCA AAAAGGGCGA CACCTTTGAT GAGCAAAAAT TAGAGCATGC TAAAACGGCT 420TTAAAAACGG CTTTAGAGGG GCAGGGCTAT TATGGGAGCG TGGTGGAGGT GCGCACAGAA 480AAGGTCAGTG AGGGAGCGTT ATTGATCGTG TTTGATGTGA ATAGGGGGGA CAGTATTTAT 540ATCAAACAAT CCATTTATGA GGGAAGCGAT AAATTAAAAC GCCGTGTGAT TGAATCTTTG 600AGCGCGAACA AGCAGCGCGA TTTCATGGGC TGGATGTGGG GCTTGAATGA CGGGAAATTG 660CGCTTAGATC AATTAGAATA CGATTCTTTG CGTATCCAAG ATGTGTATAT GCGTAGGGGT 720TACTTAGACG CTCATATTTC TTCGCCTTTT TTGAAAACGG ATTTTTCCAC CCATGACGCT 780AAGCTCCATT ATAAGGTCAA AGAGGGGATC CAATACAGGA TTTCAGATAT TTTAATAGAG 840ATTGACAACC CGGTAGTCCC CTTAAAAACC TTAGAAAAAG CGCTTAAAGT TAAAAGGAAA 900GATGTCTTTA ATATTGAGCA TTTAAGAGCG GATGCGCAAA TTTTAAAAAC CGAAATCGCC 960GATAAGGGCT ATGCGTTTGC GGTGGTGAAG CCAGACTTGG ATAAAGACGA AAAAAACGGG 1020CTTGTGAAAG TCATTTATCG TATTGAAGTG GGCGATATGG TGCATATCAA TGATGTCATC 1080ATTTCAGGGA ACCAGCGCAC GAGCGATAGG ATCATTAGGA GGGAATTGTT ACTAGGGCCT 1140AAAGATAAAT ACAACTTGAC CAAACTGAGA AATTCCGAAA ATTCTTTGAG GCGTTTAGGG 1200TTTTTCTCTA AAGTCAAGAT TGAAGAAAAA AGGGTCAATA GCTCATTGAT GGATTTGTTA 1260GTGAGCGTAG AAGAGGGGCG CACCGGGCAG TTGCAATTCG GGTTGGGCTA TGGCTCTTAT 1320GGAGGGCTCA TGCTTAATGG GAGCGTGAGC GAAAGGAATC TTTTTGGCAC AGGGCAAAGC 1380ATGAGCTTGT ATGCTAACAT TGCCACAGGG GGGGGTAGAT CTTATCCGGG CATGCCAAAA 1440GGGGCGGGGC GTATGTTTGC CGGGAATTTG AGCTTGACTA ATCCAAGGAT TTTTGACAGC 1500TGGTATAGCT CTACGATCAA TCTTTATGCG GATTACAGGA TAAGCTACCA ATACATCCAA 1560CAAGGCGGGG GCTTTGGGGT GAATGTCGGG CGCATGCTGG GTAATAGAAC CCATGTGAGC 1620TTAGGGTATA ACTTGAATGT TACCAAACTC CTTGGTTTCA GCAGCCCCTT ATACAACCGC 1680TACTATTCCT CTGTTAATGA AGTGGCCTCT CCAAGGCAAT GTTCCACACC CGCATCGGTG 1740ATTATCAACC GCTTATCAGG CGGTAGAACT CCATTGGTTC CTGAAAGCTG TTCTAGTCCT 1800GGAGCGATCA CCATCTTCAC CAGAAATAAA AGGTATTTGG GATAG 1845(2) SEQ ID NO 453 information

Sequence properties:

(A) length: 1131 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1131

(xi) sequence representation: SEQ ID NO:453: TTGTGTGAGG GCCCTAACGT GATGAGCGGT TGGAAACCCC ACATCAAGCA TGGCGTTTAT 60AGAAACTGGA ATAACTGGCG CAACAATTAC ACAGCGGTCT ATTTGAGCGA TCGCATTGAA 120GCTTGGGACG GGCGCTTTTT CATCGTGCCT GGTTTGCGCT ACGCTTTTGT GCAATACAAC 180AACGAAAATG CGTCTAACTG GATGCAAATC CCTGAGAAGG ATTTAAGAAA AATCAAGCAC 240ATGAACAATT GGATGCCCTC AACCAACATT GGCTTTATCC CTGTGCAAGG CGATCACAAT 300GTGCTTACCT ACTTCAACTA CCAACGCTCT TTCGTCCCGC CTCAATTAGA CGTTTTGAGC 360TATGGAGGAG CGGAGTATTT TACCCAACAC TTTGACACGG TGGAAGCAGG AGCGCGCTAC 420ACCTATAAAG ATAAATTCAG CTTCAATGCG GACTACTTTA GGATTTGGGC GCGCGATTTT 480GCCACCGGGC AGTATTCAGT CTATACGAGC GGGCCCATGA AAGGTAATGT GCGCCCCATT 540AATCGCTATT CTCAAGGCGT GGAGCTGGAA TTGTATTACA GGCCCATTAG AGGGTTGCAA 600TTCCATGCCG CTTTCAACTA CATTGACACT CGTGTAACTA GCCATGGCCC TTTAACCGAC 660TTGAACGGGG ATGTGCTAAA AGGGACTAGC TATAACAAGC ATTTCCCTTT TGTAAGCCCT 720TTCCAATTCA TTTTTGACGC TCGCTACAAT TGGCGTAAAA CCACCATTGG TATTTCTAGC 780TATTTTTATA GCCGTGCTTA TAGCGGGATT AGCAACAGCG CAGCAGGAGG CTATTATGGG 840ATGCAATACT ATAGTGGGGG GAACAACTAT GAAAGCGTTC TTAATAGCGG TTATCAATGC 900GAAGCTTGGT GTATGACCCA ACATGAAGGG CTCTTGCCTT GGTATTGGGT GTGGAATATC 960CAAGTGAGCC AAATTTTCTG GGAAAACGGA AGACACAGAG TTACAGGAAG CTTACAAATC 1020AATAACATCT TCAACATGAA GTATTATTTT ACAGGGATTG GCTCTAGCCC TGCAGGCTTG 1080CAACCTGCGC CTGGAAGATC GGTTACAGCG TATTTGAACT ACACTTTCTA A1131 (2) SEQ ID NO:454 information.

Sequence properties:

(A) length: 1866 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1866

(xi) sequence representation: 454: TTGCATGCTG AAGACAACGG CTTTTTTGTG AGCGCGGGCT ATCAAATCGG CGAAGCGGTG 60CAAATGGTCA AAAACACCGG CGAATTGAAA AACTTGAACG ACAAATACGA GCAGTTAAGC 120CAATCTTTAG CCCAACTGGC TTCGTTAAAA AAAAGCATTC AAACGGCGAA CAACATTCAG 180GCTGTCAACA ATGCTTTAAG CGATTTAAAA AGCTTTGCGA GTAACAACCA CACAAACAAA 240GAAACATCGC CCATCTACAA CACCGCGCAA GCTGTTATCA CTTCAGTATT GGCTTTTTGG 300AGTCTTTATG CAGGGAACGC TCTCAGTTTT CATGTGACCG GTTTGAATGA TGGATCTAAT 360TCTCCTTTAG GAAGAATCCA TAGAGATGGG AACTGCACAG GATTACAACA ATGTTTTATG 420AGCAAAGAAA CTTATGATAA AATGAAGACA CTTGCCGAAA ACCTCCAAAA AGCTCAAGGC 480AATCTCTGTG CCTTATCAGA ATGCTCTAGC AATCAATCAA ATGGAGGCAA AACTTCCATG 540ACTACAGCTC TTCAAACCGC GCAACAGCTC ATGGACTTAA TCGAACAGAC CAAGGTTTCT 600ATGGTGTGGA AAAATATCGT CATCGCAGGT GTTACAAACA AACCCAATGG TGCTGGCGCT 660ATCACATCCA CTGGTCATGT AACCGACTAT GCGGTCTTTA ACAACATCAA GGCGATGCTA 720CCTATCTTGC AACAAGCGCT TACGCTTTCT CAAAGTAACC ACACCCTATC CACTCAGTTG 780CAAGCTCGAG CTATGGGATC TCAAACAAAT CGTGAATTCG CTAAAGACAT CTACGCTTTA 840GCTCAAAACC AAAAGCAAAT CCTTTCTAAC GCTTCAAGTA TCTTCAATCT CTTTAATTCC 900ATTCCTAAAG ACCAACTTAA GTATTTGGAG AACGCTTACT TGAAAGTGCC ACATTTGGGT 960AAAACCCCTA CTAACCCTTA CAGACAGAAT GTGAATTTGA ATAAAGAAAT TAATGCGGTT 1020CAAGACAATG TAGCTAATTA TGGTAATCGT TTGGATTCGG CTTTAAGCGT GGCTAAAGAT 1080GTTTATAACC TAAAATCCAA TCAAACAGAG ATCGTAACCA CTTATAACGA TGCTAAGAAT 1140TTGAGCGAAG AGATTTCTAA ACTTCCCTAT AACCAAGTCA ATGTAACAAA CATCGTTATG 1200TCGCCTAAAG ATTCTACAGC GGGCCAATAC CAAATCAACC CAGAGCAGCA ATCCAATCTT 1260AACCAAGCTT TAGCGGCGAT GAGCAATAAC CCCTTTAAAA AAGTGGGCAT GATCAGCTCT 1320CAAAACAATA ACGGCGCTTT GAACGGGCTT GGCGTGCAAG TGGGTTATAA ACAATTCTTT 1380GGCGAAAGCA AAAGATGGGG GTTAAGGTAT TATGGTTTCT TTGATTACAA CCACGGCTAT 1440ATCAAATCCA GCTTTTTTAA TTCTTCTTCT GATATATGGA CTTATGGCGG TGGGAGCGAT 1500TTGTTAGTGA ATTTTATCAA CGATAGCATC ACAAGAAAGA ACAACAAGCT TTCTGTGGGT 1560CTTTTTGGTG GTATCCAACT AGCAGGGACT ACATGGCTTA ATTCTCAATA CATGAATTTA 1620ACAGCGTTCA ATAACCCTTA CAGCGCGAAA GTCAATGCTT CCAATTTCCA ATTTTTGTTC 1680AATCTCGGCT TGAGGACGAA TCTCGCTACA GCTAAGAAAA AAGACAGCGA ACGTTCCGCG 1740CAACATGGCG TTGAACTGGG CATTAAAATC CCTACCATTA ACACCAATTA TTATTCTTTT 1800CTAGGCACTA AGCTAGAATA CCGAAGGCTT TATAGCGTGT ATCTCAATTA TGTGTTTGCT 1860TATTAA 1866(2) SEQ ID NO 455 information

Sequence properties:

(A) length: 492 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 492

(xi) sequence representation: SEQ ID NO 455: ATGATGCGAG AGATCCTTAC TAACCGCTTT TTCCCAAGCC TTTTTAAAAA AAGGCTTGAT 60TTTTCTAACA GAGTGGTTTT AGGGCTGGGA TCTAATCTTA AAAACCCTTT AAAAATATTA 120AAAAGTTGTT TTTTATATTT TAAAAATCAT AGTAAAATCG GGAAAATTTT TTCTTCACCC 180ATTTATATCA ATCCGCCTTT TGGTTACACT AATCAACCTA ACTTTTATAA CGCTACGATT 240ATCCTTAAAA CATCTTTAGG TTTGCGCCAT TTTTTTGCTC TAGTGTTTTA TATAGAAAGG 300CGTTTTGGGC GTGCAAGGAA GCGCGATTTT AAAGATGCTC CAAGAACTTT AGATATTGAT 360ATTATCGCTT TCAATCAAGT CATTTTGAGG CAGAATGATT TGACTTTACC TCACCCTAAA 420TGGAGTGAAA GAGACTCGGT GTTAGTGCCT TTAACTTTAC AACAAATCCT TTTTAAAAGA 480GAAGAGTGGT GA 492(2) SEQ ID NO 456 information

Sequence properties:

(A) length: 858 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 858

(xi) sequence representation: SEQ ID NO 456: ATGCAAGATT TTATTAAGAT TTTTATTCAA GAGGTTGTCT CTACTTTAGA AGGGTTAGTG 60GGTAAGGCTC CAAGCGTAGG ATTAGAAAAA GAAGTTTCTA ACAATGAAGA AGCGAGTTTA 120ATCAGCACTC CTTATGCAAG GGTTAAGATT AGCGCGATTG AAAAAAATGA AAGTCCTATT 180GAATTACTGG CTCCGGTAGA TTTAGTTACC GCTTTGAGCG ATTTGATGCT AGGAGGTGAG 240GGGGCGAGCA AGGAAGAAAT GGATAATGAC GATTTAGACG CTTTTAAAGA AATGGCTTCT 300AATATTTTTG GTGCGATCGC TACAAGCTTG AAGTCTCAAG AATTGCTCCC TAAACTCAAT 360TTCACCACCA CGAACGCTGA AATCGCTAAA GAGCTTCCTA AAAAAGAAGA TTACGCTAAG 420GCGATGGTGT TTTCTTTTAA AATGGAAGCC ATCAAAGAAA GCCAAATCGT TTTATTGATC 480ACTTCAGCGT TTGAGGGCCA ATTTGAAAAA ACGCATAAAG AAGAAAAAGA AGAAACGACA 540AAAAGCGCTA CTGAAGAGAC TAAAACCCAC GACGCGTCTT TAGAAAATAT AGAAATCCGC 600AATATCAGCA TGCTTTTAGA CGTGAAATTG AACGTTAAGG TGCGTATCGG TCAAAAAAAG 660ATGATTTTAA AAGATGTGGT CTCTATGGAT ATAGGGAGCG TGGTGGAGTT GGATCAATTG 720GTGAATGACC CTTTAGAAAT CCTCGTAGAT GACAAGGTGA TCGCTAAGGG CGAAGTGGTG 780ATCGTGGATG GGAATTTTGG CATTCAAATC ACGGATATTG GCACTAAAAA GGAACGATTA 840GAGCAACTGA AAAATTAA 858(2) SEQ ID NO 457 information

Sequence properties:

(A) length: 513 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 513

(xi) sequence representation: SEQ ID NO 457: ATGAAAATTT TAGTGATTCA AGGGCCTAAT TTAAACATGT TAGGACACAG AGACCCAAGA 60CTTTATGGCA TGGTAACCTT AGACCAAATC CATGAAATCA TGCAAACTTT CGTGAAGCAA 120GGCAATTTAG ATGTGGAATT AGAGTTTTTT CAAACCAATT TTGAGGGCGA AATCATTGAT 180AAAATCCAAG AGAGCGTGGG CAGCGATTAT GAGGGGATTA TCATTAACCC TGGAGCGTTT 240TCGCACACTT CTATTGCGAT TGCGGATGCG ATCATGCTAG CGGGCAAACC TGTCATTGAA 300GTGCATCTCA CTAACATTCA AGCCAGAGAA GAATTCAGGA AAAATTCTTA CACCGGAGCG 360GCTTGTGGAG GCGTGATCAT GGGATTTGGC CCGCTTGGCT ACAACATGGC TTTAATGGCG 420ATGGTCAATA TTTTAGCCGA AATGAAAGCG TTCCAAGAAG CCCAAAAAAA CAACCCTAAT 480AACCCCAATA ACCCGATCAA CAATCAAAAA TAA 513(2) SEQ ID NO 458 information

Sequence properties:

(A) length: 1074 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1074

(xi) sequence representation: SEQ ID NO 458: ATGAGAGGAT TAGAAAGAGA ATCGCATTTC ACGCTCAATG AAAACGCGAT GTTTTTTGAG 60TGCGCTTATA GTTGCGATAA CGCTTTGTTT TTGCAATTAG ACGATCGCTC GTTCTTTATC 120ACTGATTCTC GTTACACCCA AGAAGCTAAA GAAAGCCTTC AGCCTAAAAA GGGCGTTTTA 180GTGGAAGTGA TAGAGTCTAG CGATTTAGTC CAAAGCGCGA TTGATTTAAT TACAAAGAGT 240TCGGTTAAAA AGCTCTTTTT TGACCCCAAT CAAGTGAATT TGCAAACCTA CAAGCGTTTG 300GATTCAGCGG TTGGGAATAA GGTTGTTTTA GAGGGCGTGC CCAGTTACCA CCGCCAAAAA 360CGCATCATTA AAAACGAGCA TGAGATCCAA CTCCTCAAAA AATCTCAAGC GTTGAATGTT 420GAAGCTTTTG AAAATTTTGC CGAGTATGTG AAAAAGATTT TTGATGAAAA AGAGTCATTG 480AGCGAGCGGT ATTTGCAGCA TAAGGTTAAA GACTTTTTGA CTAAAGAGGG GGTTTATGAT 540CTGAGTTTTG AGCCTATTTT AGCCTTGAAT GCGAACGCGA GCAAACCCCA TGCCTTGCCT 600AGTGCGAAGG ATTTTTTAAA AGCGGATCAT AGCATTCTTT TGGATATGGG GATCAAATAC 660GAACGCTATT GCTCTGATAG GACTCGCACG GCTTTTTTTG ACCCTAAAGA CTTTGTGTTC 720AAAAGGGAGC AGAGTTTCAA GGATAAAGAG CGTCAAAAGA TTTATGACAT TGTGAAAGAA 780GCGCAAGAAA AGGCTATTTC AGGCATTAGA GCGGGCATGA CCGGTAAAGA AGCGGACAGC 840TTGGCTAGGG GAGTGATTAG CGATTATGGT TATGGGCAGT ATTTCACTCA CAGCACCGGG 900CATGGCATTG ACTTAGACAT TCATGAGCTT CCCTATATTT CATCGCGCAG TGAAACCATT 960TTAGAAGAGG GCATGGTGTT TTCTGTAGAG CCTGGGATTT ATATCCCTGG GTTTTTTGGG 1020GTGCGCATTG AGGATTTAGT GGTGATTAAA AATTCTAGGG CCGAGCTTTT ATGA 1074(2) SEQ ID NO 459 information

Sequence properties:

(A) length: 1158 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1158

(xi) sequence representation: SEQ ID NO:459: ATGAAAGATA GTTTTCTTTT CACTTCCGAA TCAGTAACCG AAGGGCATCC TGATAAAATG 60GCCGATCAGA TCAGCGATGC GGTTTTAGAT TACATTATTG AGCGGGATAA AAAAGCCAAA 120GTCGCATGCG AGACTTTAGT TTCTAATGGT TTTTGCATGA TCACTGGCGA GTTAAAAACT 180TCTGTTTATG CCCCGATGCA AGAGATCGCA AGAGAAGTGG TTAAAAAAAT TGGCTATACA 240GACGCTCTTT ATGGCTTTGA TTACAGAAGC GCGGCGGTTT TAAATGGCAT TGCCGAGCAA 300AGCCCTGATA TTAATCAAGG CGTGGATAGA GAAGATGGCG AGATTGGGGC GGGGGATCAA 360GGGCTTATGT TTGGTTATGC ATGCAAAGAG ACTGAAACGC TCATGCCTTT ACCCATCCAT 420TTAGCGCACC AGCTCGCTTT CGCTCTAGCT CAAAAAAGAA AAGACAACAC CTTGCCTTTT 480TTAAGGCCTG ATGGCAAGTC TCAAGTGAGC GTGCGTTATG AAAACAACAA GCCTGTAAGC 540GTTGATACGA TTGTCATTTC CACCCAACAT TCCCCAGAAG TTTCACAAAA GCATTTAAAA 600GAAGCGGTGA TTGAAGAGAT CGTGTATAAG GTTTTACCCA AAGAATATTT GCATGACAAT 660ATCAAGTTTT TTATAAACCC TACAGGAAAA TTCGTCATCG GTGGGCCTCA AGGCGATGCG 720GGTTTGACAG GTAGAAAAAT CATCGTGGAT ACTTATGGAG GGTTTTGCCC GCATGGAGGG 780GGAGCGTTTA GCGGGAAAGA CCCTAGCAAG GTGGATAGGA GCGCGGCTTA TGCGGCCCGC 840TATGTGGCTA AAAATTTGGT AGCGAGCGGG GTTTGCGATA AAGCGACCGT GCACCTTGCT 900TATGCGATTG GGGTGATAGA GCCTGTGTCT ATTTATGTGA ACACGCATAA CACGAGCAAG 960CATTCAAGCG CGGAGTTGGA AAAATGCGTG AAATCGGTTT TCAAACTCAC GCCAAAAGGC 1020ATCATTGAAA GCTTGGATTT GTTAAGACCC ATTTATTCGC TCACTTCAGC TTATGGGCAT 1080TTTGGGCGCG AGTTAGAAGA ATTCACTTGG GAAAAGACTA ACAAGGTTGA AGAGATTAAA 1140GCGTTCTTTA AGCGTTAA 1158(2) SEQ ID NO:460 of information.

Sequence properties:

(A) length: 657 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 657

(xi) sequence representation: 460: GTGTTAGATA GTTTTGAGAT TTTAAAGGCT TTAAAGAGCT TGGATTTATT GAAAAACGCC 60CCTGCTTGGT GGTGGCCTAA CGCTTTGAAA TTTGAAGCTC TACTAGGAGC GGTTTTAACG 120CAAAATACTA AATTTGAAGC CGTTTTGAAA TCTTTAGAAA ATCTAAAAAA CGCTTTCATT 180TTAGAAAATG ATGATGAGAT CAATCTTAAA AAAATCGCTT ATATAGAGTT TTCAAAGCTT 240GCAGAGTGTG TCCGCCCTAG CGGGTTTTAT AACCAAAAAG CCAAACGACT GATTGATTTG 300AGCAAGAATA TTTTAAAAGA CTTTCAAAGT TTTGAAAATT TTAAACAAGA AGTAACCAAA 360GAGTGGCTTT TAGACCAAAA GGGCATTGGC AAAGAAAGCG CGGATGCGAT TTTATGCTAT 420GTGTGCGCCA AAGAAGTGAT GGTGGTGGAT AAATACAGCT ATCTTTTTTT AAAAAAATTA 480GGCATAGAGA TAGAAGATTA TGATGAATTG CAGCATTTTT TTGAAAAAGG CGTTCAAGAG 540AATTTAAATT CCGCCTTAGC GCTTTATGAA AACACCATTT CTTTAGCGCA ACTTTATGCG 600AGATTCCATG GAAAGATCGT GGAATTTTCC AAACAAAAAT TGGAATTGAA GCTTTGA 657(2) SEQ ID NO 461 information

Sequence properties:

(A) length: 399 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 399

(xi) sequence representation: SEQ ID NO 461: ATGAAACAAC TATTTTTGAT TATTGGAGCC CCAGGGAGTG GTAAAACCAC TGACGCAGAG 60CTTATCGCTA AGAATAACAG CGAAACAATC GCTCATTTTT CTACTGGGGA TTTACTCAGG 120GCTGAGAGCG CTAAAAAGAC TGAGCGAGGC TTATTGATTG AGAAATTCAC TTCTCAAGGC 180GAATTAGTGC CTTTAGAAAT TGTGGTAGAA ACGATCCTTT CAGCGATTAA AAGCTCTAGT 240AAAGGGATCA TTTTAATTGA TGGCTATCCC AGGAGCGTGG AGCAAATGCA AGCTTTGGAT 300AAGGAATTGA ACGCTCCAAA TGAAGTGATT TTAAAAAGCG TGATTGAAGT AGAAGTGAGC 360 GAAAACACCG CTAAAGAAAG GGTTTTAGGG CAGTTTTAG 399(2) SEQ ID NO 462 information

Sequence properties:

(A) length: 462 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 462

(xi) sequence representation: SEQ ID NO 462: ATGCATTATT CTTATGAAGC CTTTTTAAAA GACAGCCTGG AGTTAGCTAA ACAAGTGGAG 60CGCCTTTGCG GTATCCCAGA AGCCCTTGTG TGCGTGATGC GAGGGGGCAT GACTTTAGTG 120CATTTTTTGA GTTTGCACTG GAATTTAAGG GAAGTTTATG GCATCAATGC GATTTCTTAT 180GACACCACCA AGCGACAAAA CGCCCTAAAA ATTGAAAATA CCCCCACGAT CAAAGATCAT 240TTAAAAACCA TTTTAGTGGT AGATGAAATC GTAGATAGCG GTAATTCTTT GGAAGCGGTA 300CTTAAAGTGT TGCAAGACAA ACACCCTGAT AAAAAGTTTT ATAGCGCGAG TTTGTTCCAA 360AAAACAAGCG CGAAATACAA AGCCGATGCG TTTTTAAAAG ACGCTCCTGA ATGGATTGAT 420TTCTTTTGGG AAGTGGATTT GAAAAACTTG AAAAGCCACT GA 462(2) SEQ ID NO 463 information

Sequence properties:

(A) length: 708 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 708

(xi) sequence representation: SEQ ID NO 463: TTGTCTGAAC CCATAGATAG ATTCACACGC ATAAGGTGGT TGTTTAAAAA CGATTTTGAA 60AAAATCCGCC AACAAAGGGT TTTAATCTGT GGCGTGGGGG GCGTTGGAGG CTTTGCACTA 120GATTCTTTGT ATCGTGTGGG GATAGGGCAA ATCACTATCA TTGATAAAGA CATGTTTGAT 180GTTACCAATC AAAACCGCCA GATTGGATCA GAAAGGATAG GAGAATCTAA AGTGTTGGTG 240TTGCAAGATC TCTATAAAGG CATCCAAGCT TTAAATTGTC GCATAGATGA AGCGTTTTTA 300AATTCATTTA ATTTTAGAGA TTATGATTAC ATTTTAGATT GCATGGACGA TTTGCCTATT 360AAAACAAGCC TAGCGATAAA ATGTCAAAAT TTCGCTTACG GGAAGTTTAT CAGCTCTATG 420GGGAGCGCGA AGCGTTTGAA TCCTAAACAC ATCCAAGTGG GGAGCGTGTG GGAAAGCTAT 480GGCGATAAAT TCGGGCGTAA ATTTAGGGAT TTTTTAAAAA AACGCCGTTT TAAGGGGGAT 540TTTAAGGTGG TTTTTAGCCC TGAAGTCCCG CATTGCATAG AGCTTGGAAG CTTTAATGCG 600GTTACGGCGA GTTTTGGTTT GCAAATAGCG AGTGAAGTCGTGCAAGATAT TATCAAAAAT 660GAAAGGCAAT GGAATGAAAG ATTACGAAGA CGAATTGGAA GATTTTGA 708(2) SEQ ID NO:464 information

Sequence properties:

(A) length: 1320 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1320

(xi) sequence representation: SEQ ID NO 464: ATGCAAGTTA AAGAAAACAA ACAACTCTGC TTGATCTCAT TAGGTTGTTC TAAAAATTTA 60GTGGATTCAG AGGTGATGTT AGGCAAGCTT TATAATTACA CGCTCACTAA TGACGCTAAA 120AAAGCCGATG TGATCCTTAT CAACACTTGC GGTTTTATTG AAAGCGCTAA ACAAGAGAGT 180ATCCAAACCA TTCTCAACGC AGCCAAAGAC AAAAAAGAGG GAGCGATTTT AATTGCGAGC 240GGGTGCTTGA GCGAGCGCTA TAAAGATGAA ATCAAAGAAT TGATCCCTGA AGTGGATATT 300TTTACCGGCG TGGGGGATTA TGACAAGATT GATATTTTAA TCGCTAAAAA ACAAAACCAA 360TTCAGCGAGC AGGTGTTTTT AAGCGAGCAT TATAACGCGC GCATTATCAC GGGATCGAGC 420GTGCATGCTT ACGTTAAAAT TTCTGAGGGC TGTAACCAAA AATGCTCTTT TTGCGCTATC 480CCTAGCTTTA AGGGAAAATT ACAAAGCAGG GAATTAGACT CCATTTTAAA AGAAGTAGAA 540GATCTAGCCC TTAAAGGCTA TAAAGATATG ACTTTTATCG CTCAAGATTC TAGCTCATTT 600TTATACGATA AGGGGCAAAA AGACGGCTTG ATCCAGCTCA TTAGAGCGAT TGACAAACAG 660CAAGCCTTAA AGAGCGCGCG TATTTTATAC CTCTACCCCT CTAGCACCAC TTTAGAGCTG 720ATTGGCGCGA TTGAAGACTC GCCTATTTTT CAAAATTATT TTGACATGCC CATCCAGCAT 780ATCAGCGACT CCATGCTTAA AAAAATGCGG CGCAACTCCA GCCAAGCACA CCATTTAAAG 840CTTTTAAACG CCATGAAGCA GGTTAAAGAA AGCTTTATAA GAAGCACGAT CATTGTAGGG 900CATCCAGAAG AAAATGAGAG CGAATTTGAA GAATTGAGCG CGTTTTTAGA CGAGTTCCGG 960TTTGACAGAT TGAATATTTT TGCTTTCAGT GCTGAAGAAA ACACGCATGC CTATTCTTTA 1020GAGAAAGTGC CTAAAAAAAT CATCAACGCC CGCATTAAAG CCTTGAATAA AATCGCTTTA 1080AAACACCAAA ACCATTCTTT TAAGGCTTTG TTGAATAAGC CCATTAAGGC GTTAGTGGAA 1140CATAAAGAGG GCGAATATTT TTACAAAGCA AGGGATTTGA GATGGGCGCC TGAAGTGGAT 1200GGGGAAATTT TAATCAATGA CAGCGAACTA ACCACCCCTT TAAAACCCGG GCATTACACG 1260ATTGTGCCTA GCGCCTTTAA AGACAATATT TTACTCGCTA AGGTTTTAAG CCCTTTTTAA 1320(2) SEQ ID NO 465 information

Sequence properties:

(A) length: 2004 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 2004

(xi) sequence representation: SEQ ID NO:465: AAAAAACCCT TTTACTCTCT CTCTCTCGCT TCATCGCTTT TAAACGCTGA AGACAACGGC 60TTTTTTATCA GCGCGGGCTA TCAAATCGGT GAAGCCGCTC AAATGGTGAA AAACACCGGC 120GAATTGAAAA AACTTTCAGA CACTTATGAG AATTTGAGCA ACCTTTTAAC CAATTTTAAC 180AACCTCAATC AGGCGGTAAC GAACGCGAGC AGCCCTTCAG AAATCAATGC TGCGATCGAT 240AATTTAAAAG CAAACACGCA AGGGCTAATT GGCGAAAAAA CCAATTCCCC GGCGTATCAA 300GCGGTGTATT TGGCGCTCAA TGCGGCGGTA GGGCTGTGGA ATGTCATCGC CTATAATGTC 360CAATGCGGTC CTGGTAACAG TGGACAACAA AGCGTAACCT TTGAGGGCCA ACCAGGACAT 420AATTCAAGTT CCATTAATTG CAATTTAACC GGTTATAACA ACGGGGTTAG CGGCCCTTTA 480TCCATTGAGA ATTTTAAAAA GCTTAATCAG GCTTATCAAA CTATCCAACA AGCTTTAAAA 540CAAGATAGCG GATTTCCTGT TTTGGATAGT GCAGGAAAAC AAGTAACTAT AACAATAACA 600ACGCAAACTA ATGGAGCTAA TAAAAGTGAA ACTACTACTA CTACTACTAC TACTAATGAC 660GCTCAAACCC TTTTGCAAGA AGCCAGTAAA ATGATAAGCG TCCTCACTAC AAACTGCCCA 720TGGGTCAATC ACAATCAAGG ACAAAACGGG GGCGCGCCGT GGGGTTTAGA TACGGCAGGG 780AATGTGTGTC AGGTTTTTGC CACGGAATTT AGCGCCGTTA CTAGCATGAT CAAAAACGCC 840CAAGAAATCG TAACGCAAGC TCAAAGCCTT AACCAGCAAA ACAATCAAAA CGCGCCGCAA 900GATTTCAATC CTTACACCTC TGCTGATAGG GCTTTCGCTC AAAACATGCT CAATCACGCG 960CAAGCGCAAG CCAAGATACT TGAGCTAGCC GATCAAATGA AAAAAGACCT TAACACTATC 1020CCAAGCCAAT TTATCACAAA TTACTTGGCA GCTTGCCACA ATGGGGGTGG GACATTACCT 1080GATGCGGGGG TTACTAACAA CACTTGGGGG GCCGGTTGCG CGTATGTGGA AGAGACGATA 1140ACGGCTTTAA ACAACAGCCT TGCGCATTTT GGCACTCAAG CTGAGCAAAT CAAGCAATCT 1200GAGTTGTTGG CGCGCACCAT ACTTGATTTT AGAGGCAGCC TTAGTAATTT AAACAACACT 1260TATAACAGCA TCACCACGAC CGCTTCAAAC ACGCCTAATT CCCCATTCCT TAAAAATTTG 1320ATAAGCCAAT CCACTAACCC TAATAACCCC GGGGGCTTAC AGGCCGTTTA TCAAGTCAAC 1380CAAAGCGCTT ATTCGCAATT ATTAAGCGCC ACGCAAGAAT TAGGGCATAA CCCTTTCAGA 1440CGCGTTGGAT TAATCAGCTC TCAAACCAAC AATGGTGCCA TGAATGGGAT CGGTGTGCAA 1500GTGGGCTACA AACAATTTTT TGGTGAAAAG AGAAGGTGGG GGTTAAGGTA TTACGGCTTT 1560TTTGACTATA ACCATGCTTA TATCAAATCT AGCTTTTTCA ATTCGGCTTC TGATGTGTTC 1620ACTTATGGGG TAGGGACAGA TGTCCTCTAT AACTTTATCA ATGATAAAAC CACCAAAAAC 1680AGCAAGATTT CTTTTGGGGT GTTTGGGGGG ATTGCGTTAG CTGGCACTTC ATGGCTGAAT 1740TCCCAGTATG TGAATTTAGC GACCTTCAAT AATTTCTATA GCGCTAAAAT GAATGTGGCG 1800AATTTCCAAT TCTTGTTCAA TTTAGGCTTG AGAATGAACC TCGCTAAGAA TAAGAAAAAA 1860GCGAGCGATC ATGCGGCTCA GCATGGCGTG GAATTAGGCG TGAAGATCCC CACGATCAAC 1920ACGAATTACT ATTCTTTGCT AGGCACTCAA CTCCAATACC GAAGATTGTA TAGCGTGTAT 1980TTGAATTATG TGTTCGCTTA CTAA 2004(2) SEQ ID NO 466 information

Sequence properties:

(A) length: 264 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 264

(xi) sequence representation: SEQ ID NO 466: ATGTTTATAC TTTTTAAGTT TGGTAGGGTT TTGGGTAAGG CTTATAGCTT ATACTTATAT 60ATATATGAAA GCTTGATTTG TCAAGCTTTT GGGTTGTCAT TGAGTTGCAA TAACTCTATG 120CTGTTTTCTA CTTTTTTGAT AAATCTACCA TTACCACACA ATGAGTCCTT ATGCTGTTGT 180AGGGATATTT TAGCGTATTC TAACTCTTCA TCGCTAAAGA CATATTCATT GGAGTCAAAT 240TTTTCTTTCA ATTCTTTATT TTGA 264(2) SEQ ID NO 467 info

Sequence properties:

(A) length: 405 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 405

(xi) sequence representation: 467: ATGTTTATGG CGTCAATACG GACGCTGACG CACATGACTA ACGCTGATGG TACGATCACA 60TGCGGAGACA CGACGCCGGC GAGTTGTAAT GTGGGGATTA ACCCTAACAG CGTCTATACC 120ACAGGAAAAT TAAACGCTAA AGTGAATCAC ACGATTTTCC AATTTTTAGT GAATGTGGGC 180ATTAGAACCA ATATTTTTGA ACACCATGGC ATTGAGTTTG GTATCAAAAT CCCCACGCTC 240CCTAATTACT TTTTCAAAGG TTCTACTACT ATAAGAGCGA AAAAACAAGG CCCACTAGAG 300AATGGGAACC CGACTACTAT CACCGGAGCA GAAACCAATT TCAGCTTAAC CCAAACCTTA 360CGCCGTCAGT ATTCTATGTA TTTGCGTTAT GTTTATACTT TTTAA 405(2) SEQ ID NO 468 information

Sequence properties:

(A) length: 837 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 837

(xi) sequence representation: SEQ ID NO 468: TTGAACAAAC TGCTTAAAAA GGGGTTTTTA GCGTTCTTTT TAAGCGTGTA TTTAAGGGCT 60GATGATCTGG TTACTTATAC GATCGCCAAA GAAGAAGATC TAGGGTACCA GCGGTTTTTA 120GCCAAGAAGT GTTTAAGGGG TAAAACCCAC CCCCCATGTT TTACCGCGTC TAAAAAGCCC 180AAGAGGAAAC CTTTTAATAT AGATAAAAGC TCCCATTATT ATGGCACGAG CGTGGTGCAA 240ATGTCATGGC TACAGAGTAG GGAAAAATTT GAAAACCATT CAAAATACCG AAACATTCCT 300TTTGCTGAAG TCAGTTTGAT TTATGGCTAT AAACAATTTT TTCCTAAAAA AGAGCACTAC 360GGCTTCCGTT TTTATGTCTC TTTGGATTAC GCTTATGGCT TTTTTCTTAA AAATAAAGGC 420GCATTAGGCG ATAGTTTGAG GGCGAGTTCG CAGATCCCTA AAAGCTATAG AGAAAAATTA 480CAAAGAAAAG AGACTTTTAT TAACGCTATT TTTTATGGCG TGGGGGCTGA CTTTTTATAC 540AAACGCGCTT TTGGGACGCT GATTTTAGGG GTGAATTTCG TGGGAGAAAC CTGGTTTTAT 600GAAACAAAGA TTTTCAAACA ATGGGCTAAA GACTCTCTAA ATACTTACCG CCCCAACATG 660TTTCAAGTGA TGTTGAATGT GGGGTATCGC TACCGCTTTT CAAGGTATAA GAATTGGGCG 720ATAGAATTTG GCGCGCGCAT CCCCTTTTTA ATTAATGATT ATTTTAAAAC CCCTTTATAC 780ACCCTTCATT TCAAACGCAA TATTTCTGTC TATCTCACTT CAACTTATGA TTTTTAG 837(2) SEQ ID NO 469 information

Sequence properties:

(A) length: 1497 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1497

The sequence expression: SEQ ID NO 469: ATGAAATTAA AAAAACGAAA AGTTGCGGCT ACATTGCTAA AGCGTTTGAC CTTGCCACTA 60TTGTTCACTA CGGGTTCATT AGGGGCGGTT ACTTATGAAG TGCATGGGGA TTTTATCAAC 120TTCTCCAAAG TGGGTTTTAA CCGTTCGCCT ATTAACCCTG TTAAAGGTAT CTATCCTACA 180GAAACTTTTG TTAACCTTAC GGGTAAGCTA GAGGGGTCTG TGCATTTAGG TAGGGGATGG 240ACCGTGAATG TAGGCGGTGT TTTGGGCGGA CAAGTTTATG ATAACACTAG GTATGATAGG 300TGGGCAAAGG ATTTTACCCC CCCAAGCTAT TGGGATAAAA CTTCTTGCGG CACTGATTCT 360TTGAGCCTTT GTATGAATGC GACTAAAATG TGGCAACAGC AAGGGCCAGG TGGTATCATT 420GACCCTAGGG GTATTGGCTA TATGTATATG GGTGAGTGGA ACGGCTTGTT CCCTAATTAC 480TATCCGGCTA ACGCCTACTT GCCCGGGCAT TCAAGGCGCT ATGAAGTTTA TAAAGCGAAT 540CTTACCTATG ACAGCGACAG AGTCCATATG GTAATGGGGC GCTTTGATGT TACCGAGCAG 600GAGCAAATGG ATTGGATTTA CCAATTGTTC CAAGGTTTTT ATGGGACTTT CAAGCTTACT 660AAGAACATGA AATTCTTGCT CTTTAGCTCT TGGGGTCGTG GTATCGCTGA TGGTCAATGG 720TTGTTCCCTA TCTATCGTGA AAAGCCTTGG GGTATTCATA AGGCGGGTAT TATTTATCGC 780CCTACAAAGA ATCTAATGAT CCACCCTTAT GTGTATCTCA TCCCAATGGT AGGTACATTG 840CCCGGTGCTA AAATAGAATA CGATACCAAT CCTGAGTTTA GCGGTAGAGG TATAAGGAAT 900 63900 900AAAACGACTT TCTATGTGTT GTATGACTAT CGTTGGAATA ACGCTGAATA CGGCCGTTAC 960GCACCCGCTC GTTATAACAC TTGGGATCCG TTCTTGGATA ATGGTAAGTG GCGTGGCTTG 1020CAAGGTCCTG GTGGTGCGAC GCTCTATTTG CACCACCACA TAGACATTAA CAACTACTTT 1080GTGGTTGGTG GTGCTTACCT CAACATCGGT AACCCTAACA TGAACTTAGG TACTTGGGGT 1140AACCCTGTGG CTCTTGATGG TATCGAACAA TGGGTCGGTG GCATCTACAG CTTAGGCTTT 1200GCGGGGATTG ACAACATTAC CGATGCTGAT GCGTTCACTG AGTATGTTAA AGGTGGAGGT 1260AAGCATGGTA AGTTCAGTTG GAGCGTTTAT CAGCGCTTCA CTACCGCACC AAGGGCTTTG 1320GAATATGGTA TTGGTATGTA TCTAGACTAT CAGTTCAGCA AGCATGTTAA AGCGGGTCTC 1380AAACTCGTGT GGTTAGAGTT CCAAATCCGT GCGGGTTACA ACCCTGGAAC CGGTTTCCTT 1440GGGCCAAACG GTCAGCCGCT CAACTTGAAT AATGGTTTGT TTGAATCTTC GGCGTTC 1497(2) SEQ ID NO 470 information

Sequence properties:

(A) length: 207 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 207

(xi) sequence representation: SEQ ID NO 470: TTGAAAGAAA AATTTGATTT TTTTAAAGGC AAAAATTTTA AAATTGTCTA TTGTATTGGC 60GAAGATTTAA CGACCAGAGA AAAGGGTTTT AGGGCTGTAA AGGAATTTTT AAGCGAGCAA 120TTAGAAAATA TTGATCTTAA TTATTCCAAT TTAATTGTGG CTTATGAGCC TATTTGGGCG 180ATTGGCACTA AAAAAGCGCG CTTTTAG 207(2) SEQ ID NO 471 information

Sequence properties:

(A) length: 792 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 792

(xi) sequence representation: SEQ ID NO 471: ATGAGTAAGA GCGCGATTTT TGTTCTTTCT GGCTTTTTAG CGTTCTTGCT CTATGCTTTG 60TTATTATATG GTTTGTTGTT AGAAAGGCAT AATAAAGAAG CAGAGAAAAT CCTTTTAGAT 120TTAAATAAAA AGGACGAACA AGCCATTGAC TTGAATTTAG AAGATCTGCC AAGCGAGAAA 180AAGAATGAAA AAATTGAAAA AGTAACGGAA AAACAGGGCG ATTTTTTAGA GCCTAAAGAA 240GAACCCAAAG AAGAGCCTGA AGAAAGCCTT GAAGATATTT TTTCTTCACT CAATGATTTT 300CAAGAAAAGA CAGACAAAAA CGCTCAAAAA GACGAGCAAA AAAATGAACA AGAAGAACAA 360AGGCGTTTAA GAGAGCAACA ACGCTTGAAA CAAAACCAAG AAAACCAAGA GATGTTGAAA 420GGTTTGCAAC AAAATTTGAA TCAATTCACG CAAAAATTAG AAAGCGTTAA AAACAAGACT 480TTAGATTTGC AAATCCCTAA ACAAGATGGG GTTGATGAAA AGGCTTATCA AGAGTGGTAC 540GCTCAAATCT ATCAAATTTT ATATAAAGGC TGGAGGGGCG TTTTTTATCA CAAGGCTTCA 600GTGAGCGTGC TGATTATGAT CACTAAAGAT GGAGAGTTTG ATTATACCAT TCTTAGCTAC 660TCTGATTTTA AGGATTATAA CAAGAGCGTG ATGACCCTTT TAGATGATTT AAAGAAAGTG 720GATTTCCCCC CATATCCTGG AGGAAACATG ATTTCTATTA AAGTTAATTT TACGACTAAG 780GAAGAACAAT GA 792(2) SEQ ID NO:472 information

Sequence properties:

(A) length: 2355 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 2355

(xi) sequence representation: SEQ ID NO 472: ATGGAGCAGC CAGTCATTAA AGAAGGGACT TTAGCTTTAA TTGATACCTT TCCGTATTTG 60TTTAGAAGCT ATTACATGAG CGCTAAAAAT AAGCCTTTAA CCAACGATAA GGGCTTTCCT 120ACAGGGCTTT TAACGGGGCT TGTGGGCATG GTTAAAAAAT TTTATAAAGA CAGAAAAAAC 180ATGCCTTTTA TCGTGTTCGC CCTAGAAAGC CAGACTAAAA CTAAAAGAGC TGAAAAACTG 240GGCGAATACA AACAAAATCG TAAAGACGCC CCTAAAGAGA TGCTTTTACA AATCCCTATC 300GCCTTAGAAT GGTTGCAAAA AATGGGTTTT ACTTGCGTGG AGGTGGGAGG GTTTGAAGCC 360GATGATGTGA TCGCAAGTTT AGCCACGCTA AGCCCTTATA AAACCCGCAT TTATTCTAAA 420GATAAGGATT TTAACCAGCT TTTGAGCGAT AAAATCGCGC TTTTTGATGG CAAAACGGAG 480TTTTTGGCGA AAGATTGCGT GGAAAAATAC GGGATTTTGC CGAGTCAATT CACGGATTAT 540CAGGGCATTG TGGGGGATAG CAGCGATAAT TACAAGGGGG TTAAAGGCAT TGGGAGCAAG 600AACGCTAAGG AATTGTTGCA GCGATTAGGG AGCTTGGAAA AAATCTATGA AAATTTAGAC 660TTGGCGAAAA ATTTACTCAG CCCTAAAATG TATCAAGCCT TGATACAAGA CAAAGGAAGC 720GCCTTTTTAA GCAAAGAATT AGCCACTTTA GAAAGAGGAT GCATTAAAGA ATTTGATTTT 780TTAAGTTGCG CTTTTCCGAG CGAAAACCCC TTGTTGAAAA TCAAAGATGA ATTGAAAGAA 840TATGGTTTCA TTTCTACCTT AAGGGATTTA GAAAATTCCC CTTTCATTGT AGAAAACGTG 900CCCATATTAA ACAGCACGCC TATATTAGAC AATACCCCCG CCTTAGACAA CGCCCCTAAA 960AAATCGCGCA TGATTGTTTT AGAAAGCGCT GAGCCTTTGA GCATGTTTTT AGAAAAATTA 1020GAAAACCCTA ACGCTAGGGT TTTTATGCGT TTGGTTTTGG ATAAAGACAA AAAAATTCTA 1080GCCCTAGCGT TTTTATTACA AGATCAAGGC TATTTTTTAC CTTTAGAAGA GGCGTTGTTT 1140TCGCCCTTTT CTTTGGAATT TTTACAAAAC GCTTTTTCTC AAATGTTACA GCATGCGTGT 1200ATCATTGGGC ATGATTTAAA GCCTTTATTA AGCTTTTTAA AAGCCAAATA TCAGGTGCCT 1260TTGGAAAATA TCCGCATCCA AGACACTCAG ATTTTAGCGT TTTTAAAGAA TCCGGAAAAA 1320GTGGGGTTTG ATGAGGTTTT AAAGGAATAT TTAAAAGAAG ATTTAATCCC GCATGAAAAG 1380ATCAAAGATT TTAAGACAAA AAGTAAGGCG GAAAAATCAG AACTTTTAAG CATGGAATTA 1440AACGCCTTAA AGCGTTTGTG CGAATACTTT GAAAAAGGGG GGCTAGAAGA GGATTTGCTC 1500ACTTTAGCTA GAGACATTGA AACGCCGTTT GTGAAAGTTT TAATGGGCAT GGAATTTCAA 1560GGCTTTAAGA TTGATGCGCC TTATTTCAAG CGCTTAGAGC AGGAGTTTAA GAATGAATTA 1620AACGTTTTAG AGCGCCAAAT TTTGGATCTA ATCGGCGTGG ATTTCAACCT CAATTCGCCC 1680AAGCAACTTG GCGAAGTCTT GTATGATAAA TTAGGGCTTC CTAAAAATAA AAGCCACTCT 1740ACCGATGAAA AAAACTTGTT AAAAATCCTA GACAAGCACC CAAGCATCCC TTTGATTTTA 1800GAATACAGGG AATTGAATAA GCTTTTTAAC ACTTACACGA CCCCCTTATT GCGCTTAAAA 1860GACAAAGACG ATAAAATCCA TACCACTTTC ATCCAAACCG GCACAGCTAC CGGGCGTTTA 1920AGCTCGCATT CGCCTAATTT GCAAAATATC CCGGTGCGAT CGCCTAAAGG CTTACTCATT 1980CGTAAGGGTT TTATCGCTAG CTCTAAAGAA TATTGTTTAT TAGGGGTGGA TTATTCGCAG 2040ATTGAATTAC GCTTGTTGGC CCATTTCAGC CAGGATAAGG ATTTAATGGA AGCGTTTTTA 2100AAGGGGCGAG ACATCCATTT AGAAACTTCT AAGGCGTTGT TTGGAGAAGA TTTAGCCAAA 2160GAAAAACGAT CCATCGCTAA AAGCATTAAT TTTGGGCTGG TGTATGGCAT GGGGAGTAAG 2220AAATTGAGCG AAACTTTAAG CATCCCTTTA AGTGAGGCTA AAAGTTACAT AGAAGCGTAT 2280TTCAAGCGAT TCCCTAGCAT TAAAGATTAT TTGAATGGCA TGCGAGAAGA GATTTTAAAA 2340ACTTCTAAAG CTTTT 2355(2) SEQ ID NO 473 information

Sequence properties:

(A) length: 168 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 168

(xi) sequence representation: SEQ ID NO 473: GTGAGCGAGA GCGAAAAACA AGAAATTGAA AACAAGATAG AAGAAAGAAA ACGTGCCAAA 60GAACAAAAAG ATTTTTTAAA AGCCGATAGC ATCAGAGAAG AGCTTTTACA ACAAAAAATC 120GCTTTGATGG ACACCCCACA AGGCACGATT TGGGAGAAGC TTTTTTAA 168(2) SEQ ID NO 474 information

Sequence properties:

(A) length: 1716 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1716

(xi) sequence representation: SEQ ID NO 474: TTGCCGAGCG TTCAAATATG GGGGAGCTAC ACTAACTCGT TTAAACAAAC CTTTAGCGCA 60AGTAATAGCA ATCTGGTGAT TGGGTATAAC GCAACATGGA CTGATCCCAA TGTTTCTTCT 120AGCGACACGG TGGCTTTTGG GGACCCTTCA GGGAGCGCTC TTAATGGGCA TTGCGGGCCT 180TGGCCCTATT ACCAATGCAC AGGCACGACT AACGGCACTT ATAGCGCTTA TCATGTCTAT 240ATCACAGCGA ATCTGCGTTC TGGCAATCGT ATAGGCACCG GTGGGGCAGC CAATCTAATC 300TTTAATGGGG TAGATAGTAT CAATATCGCT AACGCTACCA TCACGCAACA TAACGCCGGG 360GCTTATTCAA GCTCTATGAC TTTTTCCACG CAAAACATGG ACAATTCGCA GAATTTGAAT 420GGCCTAAATT CTAACGGCAA GCTTTTGGTG TATGGCACAA CTTTCACTAA CCAAGCCAAA 480GACGGGAAAT TCATTTTCAA TGCAGGGCAA GCGACTTTTG AAAACACCAA CTTTAATGGA 540GGGAGTTACC AATTCAGCGG CGATAGCTTG AATTTTTCAA ATAACAACCA GTTCAATAGC 600GGTTCGTTTG AGATTGGCGC AAAAAATACT ATTTTTAATA ACGCTAATTT TAACAACAGC 660ACTTCTTTTA ATTTCAATAA TTCTAGCGCG ACCACTTCGT TTGTGGGGGA TTTCACTAAC 720GCTAATTCAA ATTTGCAAAT CGCTGGGAAC GCTGTTTTTG GGAACTCTAC TAATGGCTCT 780CAAAATACCG CTAATTTTAA TAATACCGGC TCTGTTAATA TTGCAGGGAA TGCAACCTTT 840GATAACGTGG TATTTAACAG CCCTACGAAC ACGAGCGTGA AAGGGAAAGT TACTCTCAAT 900AACATCACTT TAAAAAACTT GAACGCTCCT TTGTCTTTTG GCGATGGGAC GATTGTTTTT 960AGCGCTCATT CGGTGATTAA TATTGGTGAA GCTATCACAA ATGGCAACCC TATCACCCTT 1020GTAAGCTCTT CTAAAGCAAT TGAATACAAC GACGCTTTCA GTAAAAATCT ATGGCAGCTC 1080ATCAACTACC AAGGGCATGG GGCTAGCAGT GAAAAGCTCG TTTCTAGTGC GGGTAATGGC 1140GTCTATGATG TGGTGTATTC TCTCAACAAC CAAACCTACA ATTTCCAAGA GGTTTTTTCA 1200CCCAACAGCA TTTCTATCCG GCGTTTGGGC GTTGGCATGG TGTTTGATTA TGTGGATATG 1260GAAAAATCGG ATCGTTTGTA TTATCAAAAC GCTCTCGGTT TTATGACCTA CATGCCTAAT 1320AGCTATAACA ATAATTTAGG GAATTTAAAC AACACCATTT ACTATTACGA CAACAGCATT 1380GACTTTTATG CGAGCGGGAA AACTCTATTC ACTAAAGCGG AATTTTCTCA AACGTTCACT 1440GGGCAAAACA GCGCGATCGT TTTTGGGGCT AAAAATATAT GGACGAGCGT AAGCGATGCG 1500CCGCAATCTA ATGTGATCAT TCGCTTTGGG GACAATAAGG GAGCAGGGAG TAATGATGCG 1560AGTGGGCATT GCTGGAATTT GCAATGCATA GGCTTTATCA CAGGGCATTA TGAAGCGCAA 1620AAGATTTACA TCACCGGCAG TATTGAAAGC GGGAACCGCA TTTCTAGCGG TGGGGCGCGA 1680GCCTTAATTT TAACGGGCTT CAAGGCATTC TTTTAA 1716(2) SEQ ID NO 475 information

Sequence properties:

(A) length: 1107 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1107

(xi) sequence representation: SEQ ID NO:475: ATGGTTGTTT TAGGAAGCAC CGGCTCTATC GGGAAAAACG CCCTTAAAAT CGCAAAAAAA 60TTTGGTGTAA AAATAGAAGC CTTAAGCTGT GGGAAAAATA TCGCTTTAAT CAATGAACAA 120ATCAAAGTTT TCAAACCCAA AAAAGTAGCG ATCTTAGATC CTAACGATTT GAATAATTTA 180GAGCCTTTGG GCGCGGAAGT GTTTGTGGGG TTAGACGGCA TTGATGCGAT GATAGAGGAG 240TGCGTTTCCA ATTTAGTCAT TAACGCCATT GTGGGCGTAG CCGGATTGAA AGCGAGCTTT 300AAAAGCTTAC AAAGGAACAA AAAACTAGCC CTAGCGAATA AAGAAAGTTT AGTGAGCGCG 360GGGCATTTAT TAGACATTTC ACAAATCACG CCCGTTGATA GCGAGCATTT TGGTTTGTGG 420GCGTTGTTGC AAAACAAGAC TTTAAAGCCT AAATCTTTAA TCATTAGCGC GAGTGGGGGG 480GCTTTTAGGG ACACGCCCTT AGATCTTATC GCTATTCAAA ATGCGCAAAA CGCGCTCAAG 540CACCCTAATT GGAGCATGGG GGATAAAATC ACCATTGATT CAGCGAGCAT GGTCAATAAA 600CTTTTTGAAA TTTTAGAAAC CTATTGGCTT TTTGGTGCGT CTTTAAAGAT TGACGCGCTG 660ATTGAAAGAA GTTCTATCGT GCATGCTTTG GTGGAGTTTG AAGACAACTC TGTCATTGCG 720CATTTAGCGA GTGCGGACAT GCAATTACCC ATAAGCTATG CCATTAACCC TAAATTAGCT 780TCTTTGAGTG CTTCCATTAA ACCCTTAGAT TTATACGCTT TAAGCGCGAT TAAATTCGAA 840CCCATTAGCG TGGAGCGCTA CACTTTGTGG CGTTATAAAG ATTTGTTGTT GGAAAACCCA 900AAGCTTGGCG TGGTGCTGAA TGCGAGCAAT GAAGTGGCGA TGAAGAAGTT CTTGAATCAA 960GAAATCGCTT TTGGTGGCTT TATCCAAATC ATCTCTCAAG CTTTAGAATT GTATGCTAAA 1020AAATCTTTCA AGCTCTCTAG TTTAGATGAA GTGCTAGCGT TAGATAAGGA AGTTAGGGAG 1080CGTTTTGGAA GTGTAGCGAG AGTGTAG 1107(2) SEQ ID NO:476 information.

Sequence properties:

(A) length: 261 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type ofmolecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 261

(xi) sequence representation: SEQ ID NO 476: ATGAAAACGA CAGAAAACAC AGATGAAACT CACTTAAGGG AAACTAAAAA TAAACTAGGA 60CGCAAACCAA AAGCAGACGC TAATAAAAAA ACTCGCGCGG TAAGCTTGTA TTTTTCTGAT 120GAGCAATACC AAAAACTAGA GAAAATGGCT AACGAAGAAG AAGAAAGCGT GGGATCTTAT 180ATCAAACGCT ATATTTTGAA GGCTTTAAGA AAAATAGAAC AAGGTGGTGG CTTTATAGCT 240TTTAACTTGT TTTTAATTTA A261 (2) SEQ ID NO 477 information

Sequence properties:

(A) length: 2412 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 2412

(xi) sequence representation: SEQ ID NO:477: TTGTGGCTTA AGTCAAAATT CTTTCTTTTA ATGGGCGTGG GTTTGCTCTC CCATTCACTC 60AACGCTTTAA GCCTCACGCT CACGCAAGGC AAAGAAGAAG GAGAAGATTT TTCGGTTTTA 120ACCTTACGAA ACGATAAGGC GTTTTCTTGC TCTTATGCTA ATGAAAAACC GCCGAGCGGG 180ATTGAAGCGT CTTTATCTAT TATACACGCT AAACGCCCCA TAGAATGCGT GATAGATTCT 240ATTCCTAAAG AGGGCTTTAC CCCTTTAGAA AACGCTTTTT TCAATATCAC CTATTCCATG 300CGCCAGCAAC AATTCATTTT ACACATCAAA CCCAAAGTGA TGCGAAGGCT CACCCTTTTT 360TCTTTTGATA GGGATTATAA AAAAGCGATC CCCCTTTTTG TGGAAAACGA CGCTAAAGCC 420AAGATGTGGC AAATCATAGG CTATGATCAA AAAATCCCTT TTTTGAGCGA AAAAGACAAC 480GCTCAAAAAG GCTTGAATTT CCCCATTATC ATTAAAGACG CTCAAACCCC TATCATTCAA 540GAGCTGGATG TGAATAACAA ACCCCTACTC ACCACAAAGG GCTATGATTT AAACGCCTAT 600 GCTCAAAAAG GCTTGAATTT CCCCATTATC ATTAAAGACG CTCAAACCCC TATCATTCAA 540 600TTAGAAGCTA AAAAACAAAT GGATTCGCAA GCCTATTTTG ACGCCTTACG CACGATCAGC 660CGCGCGTTTA AAAATTACCC TCAAACGATT TTTAAAAAAG ATCTGTATTT ATTAGAAATT 720ATCGCATTAG GTAAATTAGG CATTAAAAAA TCCTTACTCA TAGATATTGG CACCCAATGG 780ATTAAAAATT ACCCGACTGA TCCTAATATC CCTGAAGCGC TATACTATGT CGCCAAAGCT 840TTAGATGAAA ACAACAATTA CAAACAAGCC GTGCGCTATT ACAAACGAAT CCTTTTAGAA 900TACAAAAACT CCCGCTACGC TCCCTTAGCC CAAATGCGTT TAGCCATTGA AGCGGCTGAA 960GGCTCTGATT TGAGCAACGC TAATATGCTT TTTAAAGAAG CTTTTTCTAA CGCCAAAGAC 1020AAAGAGAGCG CGAGTGAAAT CGCGCTTAAT TGGGCTGAAG CAGAGATAAA CTATCAAAAC 1080TTTAATAACG CTAAATATCT CATTGATAAG GTGGTTCAAT CCAACCCTGA TTATCTTTCT 1140ATGCACAGCG AATTAGCCCT AGAATTGCTC AAGTTATTGA AAAAAAACCA AATGAATGAA 1200AGTGCGATTG AGATCGCTCA CTTGCTCCTC AATCAAGATG ATGACTTGAA AGCTAAAGAG 1260CAAGCGCTCT ATGATTTAGG GGCGTTGTAT GCAAGGATCA AGGATTTTAA AAACGCCCAC 1320CTTTACAATC TGCAATATTT GCAAGACCAT GCGGAATTGG AGCGGGCTTC TGTCGTTAGA 1380GCACGCGATG AAAAAGCCCT TTTTTCAATG GAAGGGAACA CGCAAGAAAA AATCGCCCAC 1440TACGATAAAA TCATTCAAAA TTTCCCTAAT TCTAATGAAG CCCAAAAGGC TTTAGAGTTG 1500AAAGCCCAAC TCTTGTTTGA CAATAAGCAC TATGCTGAAG TTTTAGGCAT GCAAAAAAAT 1560TTGCCCAAAG ATTCTCCCTT GATCCAAAAA ACGCTCAATA TCCTTGCTAA AACCCCATTA 1620GAGGATCATC GTTGCAAAGA AGCTTTAAAA TACTTATCCC AGATCACCGC CTTTGCATTC 1680AACCCCCAAG AAGAAATCCA AGCCTTTGAT TGCTTGTATT TCGCATCGCT CAAGGAAAAA 1740GCGCAAATTA TTGCCCTAAA CGCTTTAAAA GCGGCTAAAA CCCCTAGCGA GAAATTAACA 1800TGGCTTTATC GTTTGGGGCG CAATTACTAC CGCTTAGGGG ATTTTAAAAA TTCCACTCTG 1860GCTTCTAAAG ACGCCTTAAT CCTCGCTCAA AGCTTAAATAAAAAAGAGTT TTATGACATT GCTTTTGTGT TATTTTCAGA TTACATGCAA AACAATGAAA AAGGATTGGC CCTCAATTTG 1980TATGCGTTTT TAGAAAAGCA TTTCAAAGAC GATAAACGCA TGGCGTTGGT TTATTTTAAA 2040 63 TTATTAGAGA ATGAAAAAGA CCCTAAAAGC GTTAAAATTT ATGCCACAAG CTTACTCAAA CTCCAAGACG CTTATAAGGA TTATTCTTAC ACGCCCTTTG GCGAATTTGC CCTTATTGAC 2160GCTTACAGAA CCACCAAAGA TTATTCAAAA GCGTTAGAAA CGCTAGACAA ACTCTTAAAC 2220CGCAGGCTTT CTTTAGAAGA TCACCAAAAA GCCTTATACT TGCAATCCAG CTTATTGGAT 2280TTAACCAATC AAAAAGCAAA ATCTAAAGCC AGTTTAGAAA AATGCGTTCA ATTAAAGCAA 2340 362400 AAGGAGTCAT GA 2412(2) SEQ ID NO:478 information.

Sequence properties:

(A) length: 798 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 798

(xi) sequence representation: SEQ ID NO 478: ATGATATTAA GAGCGAGCGT GTTGAGCGCG TTACTTCTTG TAGGCTTAGG GGCAGCCCCT 60AAACATTCAG TTTCAGCTAG TGACAAACGG ATGCAGGATA ATTTAGTGAG CGTGATTGAA 120AAACAAACCA ATAAAAAGGT GCGTATTTTA GAAATCAAAC CTTTAAAATC CAGCCAGGAT 180TTAAAAATGG TCGTTATTGA AGATCCGGAC ACTAAATACA ATATCCCGCT TGTAGTGAGT 240AAGGATGGTA ATTCAGTCAT AGGGCTTAGC AATATCTTTT TTAGCAATAA AAGCGATGAT 300GTGAAATTAG TTGCAGAAAC CAATCAAAAA ATCCAAGCCC TTAACGCTAC CCAGCAAAAC 360AGCGCGAAAT TGAACGCTAT TTTTAATGAA ATACCGGCTG ATTATGCGAT AGAGTTGCCC 420TCTACTAACG CTGAAAATAA GGATAAAATC CTTTACATTG TTTCTGATCC CATGTGCCCG480CATTGCCAAA AAGAGCTCAC TAAACTCAGG GATCACTTAA AAGAAAACAC TGTGAGAATG 540GTTGTAGTGG GGTGGCTTGG AGTCAATTCG GCTAAAAAAG CGGCTTTGAT CCAAGAAGAA 600ATGGCGAAAG CTAGGGCTAG GGGAGCGAGC GTGGAAGATA AAATCTCTAT TCTTGAAAAG 660ATTTATTCCA CCCAATACGA TATTAACGCT CAAAAAGAGC CTGAAGATTT ACGCACTAAA 720GTGGAAAATA CCACTAAAAA GATTTTTGAA TCTGGCGTGA TTAAGGGTGT GCCTTTCTTG 780TATCATTATA AGGCATGA 798(2) SEQ ID NO 479 information

Sequence properties:

(A) length: 684 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 684

(xi) sequence representation: SEQ ID NO 479: TTGGATTTTA AAGCGATAGA GCATGGAGAG GAAACCCTAA AAAACGAGAC TTTAAGAGCG 60TTAAGCGATT TTGCGAAGTC TAGCGATACG CATATCGTGG CATGCAGTAT TGAAAAAAAT 120AATAAAAAAC TTTACGATAG CGCTTATATC ATTCCACCAA AAGGAAAAAT CGTTGGCAAA 180CACCGCAAGA TCTATTTGTG GGGCGATGAA AAATCGCGCT TCAAAAGGGG TAAAAAATAC 240GAGGTTTTTA CGCTGGATTT TGGGGATTTT AGCGCGAAAG TGGGTTTGCA AATTTGCTAT 300GAAACTGGCT TTGGCGTGGG TGCGAACCTG CTTGTGTTAC AAGGGGCTGA GGTTTTAATC 360TATCCTAGTG CGTTTGGCAA AGCTAGGGCT TATAATTGGG ATTTGTTGAG CAAAGCTAGA 420GCGTTAGAAA ATGGCTGTTT TGTGTGCGCT TGCAATCATA GTGGGGAAGA AACTAACGCT 480AAATTAAAAC AAACGCTAGA ATTTGCCGGT GATTCAAGAA TCATCGCACC CAATGGGAAA 540ATCATCGCCC AAGCCACCAA GCTTAATGAA GTCATTATCG CCGAAATGGA TTTAAACGAA 600GTGGCACTGC AACGCCAAAA AATCCCTTAT TTACAAGATT TTGACACCAAACTCACCAAA 660AAGGGGTTTG GAAAACTCAC TTAA 684(2) SEQ ID NO 480 information

Sequence properties:

(A) length: 882 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 882

(xi) sequence representation: SEQ ID NO 480: ATGGCAAAAG AAATTTTAGT GGCTTATGGC GTGGATATTG ATGCGGTGGC TGGTTGGCTG 60GGGAGCTATG GTGGGGAGGA TTCGCCTGAT GATATTTCGC GTGGGCTTTT TGCGGGGGAA 120GTGGGGATCC CACGGCTTTT GAAATTGTTT AAAAAATACC ATCTCCCTGC GACTTGGTTT 180GCGCCGGGGC ATTCTATTGA AACTTTTCCT GAACCAATGA AAATGATCGT GGATGCAGGG 240CATGAAGTGG GTGCGCATGG GTATTCACAC GAAAACCCTA TCGCTATGAC GGCCAAGCAA 300GAAGAAGACG TTTTGTTAAA AAGCGTTGAA TTGATTAAAG ATCTCACCGG CAAAGCCCCC 360ACAGGCTATG TGGCGCCGTG GTGGGAGTTT TCTAATATCA CTAATGAATT GCTTTTAAAA 420CACGGCTTCA AATACGACCA TTCGCTCATG CACAATGATT TCACGCCCTA TTTCGTGCGC 480GTGGGGGATA GTTGGAGCAA GATTGATTAT AGTTTGGAGG CCAAGGATTG GATGAAGCCT 540TTAATCCGTG GGGTGGAAAC AAATTTAGTG GAAATCCCTG CGAACTGGTA TTTGGACGAT 600TTACCGCCGA TGATGTTTAT CAAAAAATCC CCCAATAGCT TTGGTTTTGT AAGCCCGCGC 660GATATAGGGC AAATGTGGAT CGATCAATTT GATTGGGTTT ATCGTGAGAT GGATTATGCG 720GTGTTTAGCA TGACAATCCA CCCTGATGTG AGCGCCCGTC CGCAAGTGTT GCTCATGCAT 780GAAAAAATCA TTGAGCATAT CAACCAGCAC GAGGGCGTGC GTTGGGTAAC GTTCAATGAA 840ATCGCTGATG ATTTCTTAAA ACGAAACCCT AGGAAAAAAT AG 882(2) SEQ ID NO 481 information

Sequence properties:

(A) length: 411 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 411

(xi) sequence representation: SEQ ID NO 481: GTGTGCGGCG TATTATCGTT ACAAGCGCGT TTGAGCTTTG AAAATTGCTC TAAGCCCCTA 60GACTGCTCAC TATTCGCTAC AACTTGCACC CCGCAAAACC CGATCGGCAG TTGCATGGTC 120AGCTCTCAAG GGGGCGTGTG CGGCGTATTA TCGTTACAAG CGCGTTTGAG CTTTGAAAAT 180TGCTCTAAGC CCCTAGACTG CTCACTATTC GCCACAACTT GCACCCCGCA AAACCCGATC 240GGCAGTTGCA TGGTCAGCTC TCAAGGGGGC GTGCGCGGCG TATTATCGTT ACAAGCGCGT 300TTGAGTTTTA AAAATTGCTT TTTAGTGAAA TCGCTCAAAC CCTCGCAATT GACATTGATG 360CTAACCGGTT TTTTAGGGGG GTTTTCTTTT TTGACAACCG GTTTTTGGTA A411 (2) SEQ ID NO 482 information

Sequence properties:

(A) length: 1083 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1083

(xi) sequence representation: SEQ ID NO:482: ATGAATGGTT TTTGCGCTAG ACTACGAGCC ATAACATTTA ATGAAAGACT AAAAATGAAA 60ATAGCGGTAT TACTCAGTGG GGGGGTGGAT AGCTCTTATA GCGCTTATAG CTTAAAAGAG 120CAAGGGCATG AATTAGTGGG GATTTATTTA AAACTCCATG CGAGTGAAAA AAAGCATGAT 180TTATACATTA AAAACGCTCA AAAAGCGTGC GAGTTTTTAG GCATTCCTTT AGAGGTGTTG 240GATTTTCAAA AGGATTTTAA AAGCGCGGTT TATGATGAAT TTATCAACGC CTATGAAGAA 300GGGCAAACCC CTAACCCATG CGCGTTGTGC AACCCTTTAA TGAAGTTTGG GCTAGCTTTA 360GATCACGCTT TAAAATTAGG GTGTGAAAAG ATCGCTACCG GGCATTATGC GAGGGTCAAA 420GAAATTGACA AGGTAAGTTA TATTCAAGAG GCTTTGGATA AAACTAAAGA TCAGAGCTAT 480TTTTTATACG CTTTAGAGCA TGAAGTTATC GCTAAATTGG TGTTCCCTTT AGGGGATTTG 540CTAAAAAAGG ATATTAAGCC TTTAGCCTTG AATGCGATGC CCTTTTTAGG CACTTTAGAA 600ACTTATAAGG AATCTCAAGA AATCTGCTTT GTGGAAAAAA GCTACATTGA CACTTTAAAA 660AAGCATGTTG AAGTGGAAAA AGAGGGCGTG GTGAAAAACC TACAAGGCGA AGTCATTGGC 720ACGCATAAAG GCTATATGCA ATACACGATT GGCAAACGCA AAGGCTTTAG TGTTAAAGGC 780GCGTTAGAGC CGCATTTTGT GGTGGGGATT GACGCTAAAA AGAACGAGTT GATTGTGGGC 840AAAAAAGAAG ATCTCGCCAC GCATTCGCTT AAGGCTAAAA ACAAATCTTT AACGAAAGAT 900TTTAAAGATG GCGAATACTT CATCAAGGCC CGTTACAGGA GCGTGCCTAC TAAAGCGTTT 960GTGAGCTTAA AAGATGGAAT GATTGAAGTG GAATTTAAAG AGCCTTTTTA CGGCGTGGCT 1020AAAGGGCAAG CCTTGGTCGT TTATAAAGAT GATATTTTGC TTGGCGGGGG CGTGATTGTT 1080TAA 1083(2) SEQ ID NO:483 information.

Sequence properties:

(A) length: 1074 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1074

(xi) sequence representation: SEQ ID NO 483: ATGAAAGCTA GCATTTATGA TTTCACTTTA GATGAATTGA GCCAACTTTT AAAACCAAGT 60TTTAGGGCTA AACAGCTTTA TTTGTGGCTC TATGCGAAGT ATAAAACAAG CTTTAAAGAC 120 39120 120ATGCAAAATA ATTTTTCAAA AGACTTTATC GCTTATTTGG AGCAAGAATT TACTTTGCGC 180ACGATAGAAA TCGCGCATGT GAGGGAGAGT GTTGATGGCT CTAAAAAATA CCTTTTTAAA 240TCTTTAAGGG ACAACCACAC TTTTGAAGCG GTGTTGTTGA AAATGAAAGA CAAAAAGATT 300GATGAAGAAA CGAACGCCGT TTTAGAGGGG GAAAAATACA CCGTGTGCGT GTCTTGTCAA 360ATCGGCTGTC AAGTGGGTTG CTCGTTTTGT TTCACTCAAA AAGGCGGTTT TGTAAGGGAT 420CTCAAAGCGA GCGAGATTAT CCAGCAAGCC CTACTCATTA AAGAGGCCAA TAACCTCCCC 480ATTGAAAAAG CGCTCAACAT TGTTTTTATG GGAATGGGCG AGCCTTTGAA CAATTTAGAT 540GAGGTGTGTA AAGCGGTTGA GATTTTTAAT ACCGGCATGC AAATTTCACC TAAAAGGATC 600ACCATTTCCA CGAGCGGCGT GGCCGATAAA ATCCCCATTT TAGCGGGCAA AAACTTAGGC 660GTGCAATTAG CCATATCCTT ACACGCCGTA GATGATAAAA CGCGCTCGTC TTTAATGCCC 720TTGAATAAAA AATACAACAT TGAATGCGTT TTGAATGAAG TGAGGAAATG GCCTTTAGAG 780CAGCGAAAAA GAGTGATGTT TGAATACCTT TTAATCAAAG ATTTAAACGA TAGCCTGGAT 840TGCGCTAAAA AACTTTTAAA ACTTTTAAAC GGCATTAAAT CCAAAGTGAA TTTGATCTTA 900TTCAACCCGC ATGAAGGCTC TAAGTTTGAG CGCCCTAGCT TAGAGAGCGC CAGAATGTTT 960GCGGATTTTT TAAACGCCAA AGGCTTATTA TGCACCATTA GAGAATCCAA AGCCTTGGAT 1020ATTGAAGCGG CTTGCGGGCA ATTGAGGGAG AAAAAGCTCC AGCAGAAAAT TTAA 1074(2) SEQ ID NO 484 information

Sequence properties:

(A) length: 1407 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1407

(xi) sequence representation: SEQ ID NO 484: ATGGCTGAAT GGAAAACGGA CACAGAAGAA GTCAAAAAGG TTGTTGGAAG ATGCAGGGAA 60TTTAAAAGAT CCCTGCAAGA AGAAAAATGC AGTCCATTTA TCAAAGACCT TGATAGTTAC 120GCGCTAAAAA TCATAGTGGA GCGCAGAAAA ACTGAAATGC AATTGGAAAA AGCCATAGGA 180GAATTAAAAA AAGCCAAAAG CAATGAAGAT GACGCTAAAG TTGCTTTAAG AGTCTTGCAA 240GGTGCTTCTG TCGTCTCGTG GATTTGGCCT CCTGCTAGAA TAGCTGCTAC GGCAGCCATT 300GTAGCCGCTG AAGCTGTTTT GAAATTTATG AAAGAAGACA CAGAAAAATG CAAAAGGAAT 360GTGGAGCTAT TAGAACGAAT GCTTGAAATC TACTCGAATC AAGCCAAAGC GAGCGCGAAT 420CTTATGAATC AAGCTTGGGA GGGCATTAAA AAGAGGTTGC ATTTTTATAC TGATAAGCAC 480CAGGAATTTA TCAGGCGTTT GAAACAAGCG AGCGATGCGA TAGATAACGA ATACAACTTT 540CCAACTCCAG GCGTTTTATT GGAATACGAT TTTGAACGGC CTGCTATCTC TTATACCCCT 60CAAAAAAAGCG TTTTTAATGA GCGCTTGAAG GATTTGAGGG AAAATTTTAG CGCTTCTTTA 660TACGCTGATT TGAAAGACAA GATCCATCAT AACGCCTTGT CTAACGATGA TTTAGAACGC 720ATGATAGCTT TTAGAGAGCA AGAATTTGAA AAGAGTTTAG AGGATTGGAT GGGTGCATAT 780TCTTATGATG AAAACCCTAA CGATGAATTA GATCGCATGG CAATATCTAA AGAGCAGGAG 840TTGGAAAAGA GTTTAGAGGA TTTGATGCCA AGCGTTTTAG GCGTGCCTTC TTATAACGAA 900AGCTTGACTT TAGCCAAAAA TCGTTGCGTT AAAAACTTTA AGGAAGCTTT AGAAGGTTTT 960ACAGAAAAAA TCAAAGAATC CCCTAACGAT TCAAACGCTA TCAATGAAGC CTTTGATAAT 1020TTAGAAACAG AGTTAGAGCG CGCTACAGAA AATTTGAGTC AAAAAATCGA TCCCGTTTTA 1080GAACGGAATG AAAATTATAC GCAAAAAGCG TTGGAGTATA GGGAGTTTTT AGAAAGCCGT 1140AAAGAGAGCT TTATTGTAGA TGAAAAAAAC CCCTATCCGG AAGAAGTCAG CTTTAATGAA 1200TGGCGTTGGG CGGAATTTGA TAGCGTTTTT AGCGCCATTG TGCCTTTAGA AGATTTAAAT 1260AAAACCGCAT GCGCTCATCA TGCCCTAAAG GCTTTACAAG CTACGCTAAA GACAACGATT 1320TGGGCTTTGA TGCGACAGAG TTGGAACAGA TCGCAAAAGG ATTCATCCCT AGGGGGTATT 1380TGTGGCATTT TGACGCGAAT GTTTTAG 1407(2) SEQ ID NO 485 information

Sequence properties:

(A) length: 807 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 807

(xi) sequence representation: SEQ ID NO 485: ATGAAACAAA GTTTGCGCGA ACAAAAATTA TTGAAAATTT TGGAAAATGA TGTCTTGACG 60ATTTTGGATA GTTTTTCTAA TTACCTTTTT GAACTGAGAG AAGAATTGGA CTTCATAGAA 120GAAGAAATGG AAGGTGAAAT CACTGAACAA AACCTTACCG CTCTTTATGA TTTTTCTAAT 180TTCTTAGAAG ACCATGTCAA TGTGTTTTAT GAGAATGTTT TGAATATAGA TGATGTCAAA 240ACAGAACACC TTTATTCAGG TCTCATAGAT AGTCTTAACG CTAATCTTCA CTTTGTCAAG 300TCATTTCTCA GTAATCAGGA TTTAGACTTC CGCTTTTTTA AAGAAATAAA CGATGGGCAA 360GATCCCCAAA AAACATTATC AAGATTGATT CCTCTTCAAA GTGGGAAGAA TGATGCAAGC 420TCGTTTAAAG CCAATAATTC TTTTGTTTCA TTAGTTTATG TTTATGCTTA CTTCATGCTA 480GAAACTATCA GGCAGTCGTA TAGGATTCTC AGATTACTAG AAAAACCTAT CAATAACAAC 540ATAAGCGAGG ACATGCAGAG CGATATAGAG AATTTTTTTG TTCAAGCAAA TTTTTTAGAA 600TACTATGTTC AGAACAAAAT ATACCCAACC AATCATGCCT ATGACTTCAC GCATTTGATC 660ATGGACTCCA TTATTCCTAA TTGGATTCAG ATTGATATGA GCGTTGAAGC TAAAAAGAAA 720GAGCTTTTTG AAAAATATTT TCAAAACATT GATGAAGTAA CAAACAAAAT GCTCGATCAA 780GAAAATCAAA ACAAAAACAG CGATTGA 807(2) SEQ ID NO 486 information

Sequence properties:

(A) length: 777 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 777

(xi) sequence representation: SEQ ID NO 486: TTGCTCTCTA ATAAAACGCT CCCTAAAAGA TTCGCCACTT ATAGCTTGCA AGAAGTGGGC 60GTTATTTTCC TGACCACTCA GATTTTATCT ATCATGCGCA AGACCCGTTG CTCTAAAACG 120CTTTTTTTTA TCACTAGGGG CAGGGAGAGT TTCCGCTACC AGCTGTGCGA TCATTACAAA 180CAAAAACGCC ACCAATTTGA TGAAGATTTT AGATCCCTTT TAAAAGCTCT CAAAATCGCT 240TTAGTGGAAA AATACCCCCT AAAAAAAGGG GCTAAAATCC AGGGCGAACA TTGTTTTGAA 300TATGAAGCCG ATGATATTAT CTCTTTTTAC AAAAAGAAAG ACCCCAACAA TTATGTGATA 360GCGAGCATGG ATAAGGATAT TTTGTATTCC AATAGAGGCT CTCATTTCAA TCTCAAAACG 420AACGCTTTTT TTAATGTGAG CCAAAAAGAA GCCCATTTTT TTGCTTATTA CCAATGCGTT 480GTGGGGGATA AAGGGGATAA TATTAAGGGG GTTAAAGGGA TTGGCGGCTT CAACTATAAA 540GATTTTTTAA ACGAAGACGC TAAAGAGCAT GAACTATGGG AGCAGATCAT TCAAGCGTTC 600AAAATTAAAG AAGATTTGAG CGATAGCGAA GCCAAAGAAA AGGCTCTATT AAACATGCGT 660TTAGTCAATA TGCACCAGAT GACCCACCAT GGCGTGATCA AACTATGGGA GCCTGAGTTT 720AAAAAAGCTT TTTTCCCTAA AAAACCCCAA AGACCTGATT TTAAAAGAAT TTCTTAA 777(2) SEQ ID NO 487 information

Sequence properties:

(A) length: 771 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 771

(xi) sequence representation: 487: TTGTGTTTGA AACTCTTAAT TTGGAATTTT AAGGAGCATT CTTTGAAAGT CAATTTCTTT 60GCCACTTGTC TAGGAGCAGC TATTTATAGC AACGCATCGC TTAACGCTAT CAAATTACTC 120CGCAAGGAAA ATTTGGAAGT GGTTTTTAAA AAAGACCAGA CATGTTGTGG CCAGCCAAGC 180TACAACTCAG GATACTATGA AGAGACTAAA AAAGTCGTTT TATACAATAT CAAACTTTAT 240TCCAATAACG ACTACCCTAT TATTTTGCCT AGCGGTTCAT GCACAGGGAT GATGCGGCAT 300GATTATTTGG AATTGTTTGA AGGGCATGCG GAATTTAACA TGGTTAAAGA TTTTTGCTCT 360AGGGTGTATG AATTGAGCGA GTTTTTGGAT AAAAAATTGC AAGTCAAATA CGAAGATAAG 420GGCGAACCTC TCAAAATCAC ATGGCATTCT AATTGCCATG CCTTAAGGGT GGCTAAAGTG 480ATTGACTCGG CGAAAAATCT CATCAGACAG CTTAAAAATG TGGAACTCAT TGAATTGGAA 540AAAGAAGAAG AATGCTGCGG GTTTGGGGGG ACTTTTTCAG TTAAAGAGCC TGAAATTTCA 600GCGGTTATGG TCAAAGAAAA GATTAAAGAC ATAGAGAGCC GTCATGTGGA TGTGATCGTT 660TCAGCGGATG CTGGGTGCTT GATGAATATC AGCACCGCTA TGCAAAAAAT GGGCTCTTTG 720ACAAAACCCA TGCATTTTTA TGACTTTTTA GCCTCAAGGC TTGGACTTTA A771 (2) SEQ ID NO 488 information

Sequence properties:

(A) length: 1410 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1410

(xi) sequence representation: SEQ ID NO 488: TTGAAAATAT TCGTTCTGTT GATGTCGGTA ATTTTAGGAA TATCATTAAC AGGTTGCATA 60GGCTATCGTA TGGACTTAGA ACATTTTAAC ACGCTCTATT ATGAAGAAAG CCCTAAAAAA 120GCTTATGAAT ATTCCAAACA ATTCACGAAG AAAAAAAAGA ACGCTCTTTT ATGGGACTTG 180CAAAACGGCT TGAGCGCTTT ATACGCAAGG GATTATAAGA CTTCTTTAGG GGTATTGGAT 240CAAGCCGAGC AACGCTTTGA TAAAACCCAA AGCGCTTTCA CAAGAGGGGC TCGTTATGTG 300GGCGCTACCA TGATTAATGA TAATGTACGC GCTTATGGGG GGAATATTTA TGAGGGCGTT 360TTAATCAATT ATTACAAAGC GATAGACTAC ATGCTTTTAA ACGATAGCGC GAAAGCTAGG 420GTGCAATTCA ACCGCGCGAA TGAACGCCAA CGCAGGGCTA AAGAATTTTA TTATGAGGAA 480GTGCAAAAAG CCATTAAAGA AATCGATTCT AGCAAAAAGC ACAATATTAA TATGGAACGC 540TCTAGGGCAG AAGTGAGCGA GATTTTAAAC AACACCTATT CTAATTTAGA CAAATACGAA 600GCTTATCAAG GCTTGCTTAA CCCGGCGGTT TCGTATCTTT CAGGGTTGTT TTACGCTTTA 660AATGGGGATA AGAATAAGGG ATTAGGCTAT CTTAATGAAG CCTATGGGAT CAGTCAAAGC 720CCTTTCGTGG CTCAAGACTT GGTTTTTTTC AAAAACCCTA ACAGGAGCCA TTTCACTTGG 780ATCATCATTG AAGATGGTAA AGAGCCGCAA AAAAGCGAAT TTAAAATTGA TGTGCCTATT 840TTTATGATTG ATTCGGTTTA TAACGTGAGC GTGGCCTTGC CCAAGCTAGA AAAAGGGGAA 900GCGTTTTATC AAAATTTCAC CCTCAAGGAC GGAGAAAAAG TAACACCCTT TGACACTTTA 960GCCTCAATAG ATGCGGTGGT CGCTAGCGAA TTCAGGAAGC AATTGCCCTA CATTATCACT 1020AGGGCTATTT TATCGGCCAC TTTTAAAGTG GGCATGCAAG CGGTGGCGAA CTATTATTTA 1080GGGTTTGTTG GCGGGTTAGT AACTTCGTTG TATTCAGGTG TGAGCACCTT TGCAGACACC 1140AGAAACACGA GCATTTTTGC CCATAAAATC TACCTCATGC GCATCAAAAA CAAAGCCTTT 1200GAAAGTTATG AAGTTCGAGC CGATTCCATT GACGCTTTTT CGTTTTCATT AAAGCCTTGT 1260AAAAGATCGC TTGAAAGCCC TAAAATCATT GACGCTAGGG AATTGCTTTC AGGGTTTGTA 1320ACAGCCCCAC AAGTCTTTTG CTCTAACCGC CATAATATTT TATATGTGCG CAGCTTTAAA 1380AACGGGTTTG TTTTGAGTCA TTTAAAATGA 1410(2) information of SEQ ID NO:489

Sequence properties:

(A) length: 1053 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1053

(xi) sequence representation: SEQ ID NO 489: ATGAAACAAA TAAAAGCTTT AGCCTTATTT AGTGGGGGGT TGGATAGTTT GTTGTCCATG 60AAATTACTCA TTGATCAAGG CATTGAAGTA ACCGCTTTAC ACTTCAATAT AGGGTTTGGA 120 39120 120GGGAATAAAG ATAAAAGAGA GTATTTTGAA AACGCCACCG CGCAAATTGG GGCTAAACTC 180TTGGTGTGCG ATATTAGAGA GCAGTTCTTT AACGATGTGT TGTTCAAGCC CAAATACGGC 240TATGGGAAGT ATTTCAACCC TTGCATTGAT TGCCATGCCA ACATGTTTAG GAACGCTTTT 300TATAAAATGC TTGAATTGGA TGCGGATTTT GTTTTGAGCG GGGAAGTGCT AGGGCAACGC 360CCTAAATCCC AAAGGAAAGA AGCGCTCAAT CAGGTGAGGA AATTAGTCAG AGAAGTGGGC 420GAAGAGGCTC GTTTTGATCT TATTTTAGAC CGAACGCAAG CAAGCGGTGA AAAACCGCAA 480TTTTTAGACG AATTGCTCTT AAGGCCCATG AGCGCTAAAC TCTTAGAGCC TACTTTTATG 540GAAAAAAAGG GTTGGGTTGA TAGGGAAAAG CTTTTAGATG TGAGTGGTAG GGGGCGTGCT 600AGGCAATTGC AAATGATCAA AGATTATGGC TTGAAATATT ATGAAAAGCC AGGTGGGGGG 660TGCTTGCTTA CGGACATTCA AGTGAGTAAT AAGATTAAGA ATTTGAAAGA ATACAGAGAA 720ATGGTGTTTG AAGATGGCGT GATTGTCAAA AACGGGCGTT ATTTTGTCCT ACCCCATAAC 780GCTCGTTTGG TGGTGGCAAG GAATGAAGAA GAAAACCATA AATTAGACAT TGAACACCCC 840TTAATGGATA AGATTGAATT GCTAGGCTGT AAAGGTCCTT TGAGTTTGGT GGATAAAAAC 900GCCAGCCAAG AAGATAAAGA ATTGGCCGGT CGTATCGCTT TAGGCTATGC TAAGACTTTA 960AAAAATCAAG CTTACCTCAT TCAAATAGGG AATGAAAAGC GCGAACTTTA CCCTTTGGAT 1020AAAGAGAACG CTAGGGAGTA TTTGTTCGCT TGA 1053(2) SEQ ID NO 490 information

Sequence properties:

(A) length: 1218 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 1218

(xi) sequence representation: SEQ ID NO:490: ATGAAAAAAT ACAGCGCTAT CCCCACCCCT TGCTATGCGC TAGAGAGCGA ACGCTTAGAA 60AAAAACGCCA AGATTTTAGA AATCGTGCGC CAGCAAAGCG GGGCAAAGGT TTTGCTCGCT 120TTAAAAGGGT ATGCGTTTTG GCGTGAGTTT GGGATTTTGA GGCAAAAATT GAACGGGTGT 180TGCGCGAGCG GTCTTTATGA GGCTAAGCTC GCTTTTGAAG AATTTGGGGG GCGAGAGAGC 240CATAAGGAAA TTTGCGTTTA TAGCCCGGCC TTTAAAGAGG CTGAAATGAG CGCGATTTTA 300CCCCTAGCGA CAAGCATCAT TTTCAACTCT TTTCACCAAT ACGCCACCTA CAAAGACAGG 360ATTTTAGACA AAAACAAGCA GTTAGAAAAC TTGGGCTTAA GCCCCATTAA AATGGGTTTG 420AGGATTAACC CCCTTTATAG CGAAGTAACC CCAGCGATCT ATAACCCATG CTCTAAAATG 480AGCCGGTTAG GGATTACGCC TAGCGGATTT GAAAAAGGAG TCAAAGAGCA TGGCTTAGAG 540GGGGTGAGCG GGTTGCATTT CCATACGCAT TGCGAGCAAA ACGCCGACGC TTTGTGCCGG 600ACTTTAGAGC ATGTGGAAAG GCATTTCAAG CCTTATTTAG AAAACATGGC GTGGGTGAAT 660TTTGGTGGGG GGCATCATAT CACCAGGAGC GATTATGATG TGAATTTGCT CATTCAAACG 720ATTAAGGATT TTAAAGAACG CTACCACAAT ACAGAAGTGA TCTTAGAGCC TGGGGAAGCC 780ATAGGGTGGC AATGCGGGTT TTTAATCGCA AGCGTGATAG ATATCGTTCA AAACGATCAA 840GAAATTGCGA TTTTAGACGC TTCTTTTAGC GCTCACATGC CCGATTGCCT AGAAATGCCT 900TATCGCCCTA GTATTCTTAA GGTTTCTGTA GAAAACGATG AGGAAATTAT TGA AGTTGAA 960AAGGGCGAAA ATCAAGGGGC GTTTTCTTAC TTTTTAGGCG GCCCCACTTG TTTGGCGGGG 1020GATTTTATGG GGAGTTTTAG CTTTGAAACG CCTTTAAAAA GGGGCGATAA AATCGTGTTT 1080CAAGACATGC TCCATTATAC GATCGTGAAA AACAACTCGT TTAATGGCGT GCCACTGCCA 1140AGCCTGGCTA AAATAGATTC GCAAGGTTTT AAGATCCTCA AAAGCTTTTC TTATGAAGAT 1200TATAAAAACA GGAATTAA 1218(2) SEQ ID NO:491 information.

Sequence properties:

(A) length: 966 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 966

(xi) sequence representation: SEQ ID NO 491: ATGGCTGATA GTTTAGCGGG CATTGATCAA GTTACGAGTT TACATAAAAA TAACGAGTTG 60CAATTGTTGT GTTTCAGGCT GGGTAAAAAC AAGGATTTGT ATGCGGTCAA TGTCTTTAAG 120ATCCGTGAAG TGGTGAAATA CCATGGCAAT CTCACTATCA TTAGCCACGA AAACAATTCG 180CTCGTTGAGG GCTTGATCAT TATAAGAGAG CTCACCATTC CTTTGATTGA CATGAAAAAA 240TGGTTTTATT ATGACAGCCA AAACAAGAGC AAGGATTTAC GCCCTTACAG GATAGAAAAA 300GAAAAAGGCG AAGACGATAT TGTCATGATT TGTGAGTTTT CTCGCTGGAC CATAGGGGTT 360AGGATCTATG AAGCGGATAG GATTTTGAGC AAGAAATGGA CTGAAATGGA GCAAAGCGCT 420GGGCTAGGGG GATCTGCTGG GAATAACAAA CTCGTGAGCC GCACGCGCTA TTTTGACGGG 480CGCTTGGTGC AAGTGGTGGA TATTGAAAAA ATGCTTATAG ACGTGTTCCC TTGGATTGAA 540GATGAAAAAC ACAACGATTT AGAGACGCTT TCTAAAATCC ATTCTAACCA ATGCGTTTTG 600CTCGCTGATG ATTCCCCAAG CGTCTTAAAA ACCATGCAAA TGATTTTAGA CAAGCTGGGC 660GTCAAGCACA TTGACTTTAT CAATGGTAAA ACCTTATTAG AGCATTTGTT CAACCCAACA 720ACCGATGTGA GTAATATTGG CCTGATTATT ACCGATTTAG AAATGCCAGA AGCGAGCGGT 780TTTGAAGTGA TCAAACAGGT TAAAAACAAT CCTTTGACTT CAAAAATCCC CATTGTGGTC 840AATTCTTCTA TGAGCGGCAG CTCTAATGAA GACATGGCCA GGAGTTTGAA GGCCGATGAT 900TTCATCTCCA AGTCTAACCC TAAAGACATC CAGCGGGTGG TTAAGCAATT TTTGGAATTA 960GCATGA 966(2) SEQ ID NO 492 information

Sequence properties:

(A) length: 96 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 96

(xi) sequence representation: 492 parts of SEQ ID NO: Glu Arg Ile Lys Arg Arg Ala Val Met Lys Lys Ile Val Val Ser Leu 151015 Cys Val Ala Leu Gly Phe Leu Ser Ala Asp Pro Ala Gln Ala Asn Lys

20 25 30Ala Ile Ser Asp Ala Asp Leu Ile Glu Glu Ile Arg Asp Leu Lys Lys

35 40 45Ile Ile Ser Ala Gln Asn Thr Glu Ile Asn Gln Leu Arg Lys Val Gln

50 55 60Glu Val Leu Ser Gly Gln Leu Gly Asp Met Arg Lys Asp Ile Leu Ser65 70 75 80Thr Arg Asp Tyr Cys Ile Ser Leu Arg Pro Tyr Ile Tyr Asn Trp Arg

859095 (2) SEQ ID NO 493 message

Sequence properties:

(A) length: 301 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 301

(xi) sequence representation: 493 SEQ ID NO, Asn Ala Trp Asn Asp Phe Val Lys Ser Gly Ser Leu Gly Pro Phe Ser 151015 Asn Gly Tyr Tyr Glu His Lys Thr Ile Arg Leu Asn Pro Glu Gln Asn

20 25 30Leu Ile Val Leu Ser His Tyr Leu Lys Leu Leu Glu Ile Gln Arg Glu

35 40 45Ala Ala Lys Met Thr Ala Ile Phe Gly Ala Lys Gln Pro His Pro Gln

50 55 60Ser Leu Thr Val Gly Gly Val Thr Ser Val Met Asp Ile Leu Asp Pro65 70 75 80Thr Arg Leu Ala Glu Trp Lys Ser Lys Phe Glu Val Val Ala Asn Phe

85 90 95Ile Asn His Ala Tyr Tyr Pro Asp Leu Val Met Ala Gly Glu Met Phe

100 105 110Ala Asn Glu Pro Ser Val Ile Lys Gly Cys Gly Leu Arg Asn Phe Ile

115 120 125Ala Tyr Glu Glu Val Leu Leu Gly Lys Asp Lys Tyr Leu Leu Ser Ser

130 135 140Gly Val Val Leu Asp Gly Asp Ile Ser Lys Leu His Pro Ile Asp Glu145 150 155 160Ser Leu Ile Lys Glu Glu Val Thr His Ser Trp Tyr Gln Tyr Glu Asp

165 170 175Thr Lys Glu Val Gln Leu His Pro Tyr Asp Gly Gln Thr Asn Pro His

180 185 190Tyr Thr Gly Leu Lys Asp Gly Glu Ser Val Gly Ile Glu Asn Lys Ile

195 200 205Ile Pro Ala Lys Val Leu Asp Thr Lys Asp Lys Tyr Ser Trp Ile Lys

210 215 220Ser Pro Arg Tyr Asp Ser Lys Pro Met Glu Val Gly Pro Leu Ser Ser225 230 235 240Val Val Val Gly Leu Ala Ala Lys Asn Pro Tyr Val Thr Glu Val Ala

245 250 255Thr Lys Phe Leu Lys Asp Thr Lys Leu Pro Leu Glu Ala Leu Phe Ser

260 265 270Thr Leu Gly Arg Thr Ala Ala Arg Cys Ile Glu Ala Lys Thr Ile Ala

275 280 285Asp Asn Gly Leu Leu Ala Phe Asp Ala Leu Val Glu Ile

290295300 (2) information of SEQ ID NO:494

Sequence properties:

(A) length: 169 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 169

(xi) sequence representation: 494: Gly Ile Asn Met Ser Lys Lys Ile Val Val Asp Pro Ile Thr Arg Ile 151015 Glu Gly His Leu Arg Ile Glu Val Ile Val Asp Asp Asp Asn Val Ile SEQ ID NO

20 25 30Thr Asp Ala Phe Ser Ser Ser Thr Leu Phe Arg Gly Leu Glu Thr Ile

35 40 45Ile Lys Gly Arg Asp Pro Arg Asp Ala Gly Phe Ile Ala Gln Arg Ile

50 55 60Cys Gly Val Cys Thr Tyr Ser His Tyr Lys Ala Gly Val Thr Ala Val65 70 75 80Glu Asn Ala Leu Gly Ile Thr Pro Pro Leu Asn Ala Gln Leu Val Arg

85 90 95Ser Leu Met Asn Met Ala Leu Leu Phe His Asp His Val Val His Phe

100 105 110Tyr Thr Leu His Gly Leu Asp Trp Cys Asp Ile Leu Ser Thr Leu Lys

115 120 125Ala Asp Pro Ile Gln Ala Ala Lys Leu Ser Phe Lys Tyr Ser Pro Tyr

130 135 140Pro Ile Asn Thr Gly Ala Gly Arg Ile Lys Ser Gly Ser Lys Thr Leu145 150 155 160Gly Met Ile Ser Leu Lys Ala Asp Leu

165(2) SEQ ID NO 495 information

Sequence properties:

(A) length: 185 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 185

(xi) sequence representation: glyl 51015 Ile Gly Asn Ile Leu Phe Gly Asp Glu Gly Ile Gly Val His Leu Ala of SEQ ID NO:495: Trp Leu Trp Leu His Gln Arg Met Ser Gln Lys Ile Leu Ile Leu

20 25 30His Tyr Leu Lys Arg Asn Phe Ser Phe Phe Pro Ser Val Asp Ile Val

35 40 45Asp Gly Gly Thr Met Ala Gln Gln Leu Ile Pro Leu Ile Thr Ser Tyr

50 55 60Glu Lys Val Leu Ile Leu Asp Cys Val Ser Ala Lys Gly Val Glu Ile65 70 75 80Gly Ser Val Tyr Ala Phe Asp Phe Lys Asp Ala Pro Lys Glu Ile Thr

85 90 95Trp Ala Gly Ser Ala Mis Glu Val Glu Met Leu His Thr Leu Arg Leu

100 105 110Thr Glu Phe Leu Gly Asp Leu Pro Lys Thr Phe Ile Val Gly Leu Val

115 120 125Pro Phe Val Ile Gly Ser Glu Thr Thr Phe Lys Leu Ser Ser Glu Met

130 135 140Leu Asn Ala Leu Glu Thr Ala Leu Lys Ala Ile Glu Thr Gln Leu Asn145 150 155 160Ala Trp Gly Val Lys Met Gln Arg Thr Asp His Ile Ala Leu Asp Cys

165170 175Ile Ala Glu Leu Ser Tyr Lys Gly Phe

180185 (2) SEQ ID NO 496 information

Sequence properties:

(A) length: 108 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 108

(xi) sequence representation: SEQ ID NO:496: Tyr Gln Ile Leu Asn Gln Arg Lys Thr Met Lys Lys Val Leu Leu Leu 151015 Thr Leu Ser Leu Ser Leu Ser Phe Trp Leu His Ala Glu Arg Asn Gly

20 25 30Phe Tyr Leu Gly Leu Asn Phe Ala Glu Gly Ser Tyr Ile Gln Gly Gln

35 40 45Gly Ser Ile Gly Glu Lys Ala Ser Ala Glu Asn Ala Leu Asn Gln Ala

50 55 60Ile Asn Asn Ala Gln Asn Ser Leu Phe Pro Asn Thr Gln Ala Ile Arg65 70 75 80Asp Val Gln Asn Ala Leu Asn Ala Val Lys Asp Ser Asn Lys Ile Ala

85 90 95Asn Arg Phe Ala Gly Asn Gly Gly Ser Gly Gly Ile

100105 (2) SEQID NO:497 message

Sequence properties:

(A) length: 128 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 128

(xi) sequence representation: SEQ ID NO:497: Arg Val Ser Gly Asn Leu Lys Ser Asp Gln Ser Thr Cys Ala Pro Tyr 151015 His Ile Asp Lys Asn Gln Glu Tyr Lys Gly Arg Tyr Ile Gly Gln Val

20 25 30Pro Arg Gly Met Leu Ser His Trp Val Arg Ile Lys Asn Gly Val Val

35 40 45Glu Asn Tyr Gln Ala Val Val Pro Ser Thr Trp Asn Ala Gly Pro Arg

50 55 60Asp Ser Lys Asn Gln Arg Gly Ala Tyr Glu Met Ser Leu Ile Gly Thr65 70 75 80Lys Ile Ala Asp Leu Thr Gln Pro Leu Glu Ile Ile Arg Thr Ile His

85 90 95Ser Phe Asp Pro Cys Ile Ala Cys Ser Val His Val Met Asp Phe Lys

100 105 110Gly Gln Ser Leu Asn Glu Phe Lys Val Glu Pro Asn Phe Ala Lys Phe

115120125 (2) SEQ ID NO:498 information

Sequence properties:

(A) length: 86 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 86

(xi) sequence representation: SEQ ID NO:498: Leu Tyr Gln Asn Asp Lys Gly Phe Lys Thr Glu Leu Arg Ile Leu Ser 151015 Val Phe Ile Val Glu Phe Leu Val Asn Ile Leu Gly Phe Met Leu Ala

20 25 30His Met Leu His Phe Trp Phe Leu Arg Cys Val Lys Ala Leu Ala Trp

35 40 45Leu Met Lys Thr Phe Asp Arg Arg Arg Tyr Phe Asp Ala Lys Ala Asn

50 55 60Leu Asp Phe Val Phe Gly Asp Ser Lys Ser Glu Glu Glu Lys Lys Arg65 70 75 80Ile Ile Lys Lys Gly Val

85(2) SEQ ID NO 499 information

Sequence properties:

(A) length: 67 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 67

(xi) sequence representation: 499 ID NO: Tyr Lys Lys Gly Asn Gln Ile Met Asn Ile Gln Thr Lys Lys Arg Phe 151015 Leu Ala Asn Leu Leu Leu Phe Ser Leu Phe Ser Cys Leu Lys Ala Glu

20 25 30Thr Leu Ser Glu Asp Mis Gln Ile Leu Leu Ser Ser Asp Ala Phe His

35 40 45Arg Gly Asp Phe Ala Thr Ala Gln Lys Gly Tyr Met Asn Leu Tyr Arg

505560 Ala Asn Gln65 (2) SEQ ID NO 500 information

Sequence properties:

(A) length: 256 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 256

(xi) sequence representation: 500: Leu Cys Leu Lys Leu Leu Ile Trp Asn Phe Lys Glu His Ser Leu Lysl 51015 Val Asn Phe Phe Ala Thr Cys Leu Gly Ala Ala Ile Tyr Ser Asn Ala SEQ ID NO

20 25 30Ser Leu Asn Ala Ile Lys Leu Leu Arg Lys Glu Asn Leu Glu Val Val

35 40 45Phe Lys Lys Asp Gln Thr Cys Cys Gly Gln Pro Ser Tyr Asn Ser Gly

50 55 60Tyr Tyr Glu Glu Thr Lys Lys Val Val Leu Tyr Asn Ile Lys Leu Tyr65 70 75 80Ser Asn Asn Asp Tyr Pro Ile Ile Leu Pro Ser Gly Ser Cys Thr Gly

85 90 95Met Met Arg His Asp Tyr Leu Glu Leu Phe Glu Gly His Ala Glu Phe

100 105110Asn Met Val Lys Asp Phe Cys Ser Arg Val Tyr Glu Leu Ser Glu Phe

115 120 125Leu Asp Lys Lys Leu Gln Val Lys Tyr Glu Asp Lys Gly Glu Pro Leu

130 135 140Lys Ile Thr Trp Mis Ser Asn Cys His Ala Leu Arg Val Ala Lys Val145 150 155 160Ile Asp Ser Ala Lys Asn Leu Ile Arg Gln Leu Lys Asn Val Glu Leu

165 170 175Ile Glu Leu Glu Lys Glu Glu Glu Cys Cys Gly Phe Gly Gly Thr Phe

180 185 190Ser Val Lys Glu Pro Glu Ile Ser Ala Val Met Val Lys Glu Lys Ile

195 200 205Lys Asp Ile Glu Ser Arg His Val Asp Val Ile Val Ser Ala Asp Ala

210 215 220Gly Cys Leu Met Asn Ile Ser Thr Ala Met Gln Lys Met Gly Ser Leu225 230 235 240Thr Lys Pro Met His Phe Tyr Asp Phe Leu Ala Ser Arg Leu Gly Leu

2456250255 (2) SEQ ID NO 501 information

Sequence properties:

(A) length: 255 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 255

(xi) sequence representation: 501 SEQ IDNO: Met Lys Lys Ile Phe Leu Gly Met Ala Leu Ala Phe Ser Val Ser Met 151015 Ala Glu Lys Ser Gly Ala Phe Leu Gly Gly Gly Phe Gln Tyr Ser Asn

20 25 30Leu Glu Asn Gln Asn Thr Thr Arg Thr Pro Ser Ala Asn Asn Asn Thr

35 40 45Pro Ile Asn Thr Ser Met Phe Gly Asn Asn Gln Ala Ala Pro Ala Gln

50 55 60Glu Thr Pro Ser Val Ile Asn Thr Asn Asn Tyr Gly Gln Met Tyr Gly65 70 75 80Val Asp Ala Met Ala Gly Tyr Lys Trp Phe Phe Gly Lys Thr Lys Arg

85 90 95Phe Gly Phe Arg Thr Tyr Gly Tyr Tyr Ser Tyr Asn His Ala Asn Leu

100 105 110Ser Phe Val Gly Ser Lys Leu Gly Ile Met Asp Gly Ala Ser Gln Val

115 120 125Asn Asn Phe Thr Tyr Gly Val Gly Phe Asp Ala Leu Tyr Asn Phe Tyr

130 135 140Glu Ser Lys Glu Gly Tyr Asn Thr Ala Gly Leu Phe Val Gly Phe Gly145 150 155 160Leu Gly Gly Asp Ser Phe Ile Val Gln Gly Glu Ser Tyr Leu Lys Ser

165 170 175Gln Met Gln Ile Cys Asn Asn Thr Ala Gly Cys Ser Ala Ser Met Asn

180 185 190Thr Ser Tyr Phe Gln Met Pro Val Glu Phe Gly Phe Arg Ser Asn Phe

195 200 205Ser Lys Mis Ser Gly Ile Glu Val Gly Phe Lys Leu Pro Leu Phe Thr

210 215 220Asn Gln Phe Tyr Lys Glu Arg Gly Val Asp Gly Ser Val Asp Val Phe225230 235 240Tyr Lys Arg Asn Phe Ser Ile Tyr Phe Asn Tyr Met Ile Asn Leu

2456250255 (2) SEQ ID NO 502 message

Sequence properties:

(A) length: 218 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 218

(xi) sequence representation: 502: Ala Cys Glu Ile Arg Ala Trp Ala Phe Asp Arg Met Leu Arg Val Leu 151015 Ser Val Gly Val Val Phe Ile Leu Leu Gly Cys Gln Phe Phe Asn Lys SEQ ID NO

20 25 30Thr Thr Leu His Leu Lys Tyr Lys Asp Tyr Pro Lys Asn Ser Pro Leu

35 40 45Lys Thr Ala Ser Thr Leu Thr Pro Pro Lys Ile Phe Phe Asn Ala His

50 55 60Phe Val Pro Pro Phe Tyr Gln Lys Glu Phe Lys Lys Ala Leu Ala Gln65 70 75 80Gln Ile Ala Tyr Phe Leu Lys Asp Lys Ser Ala Leu Thr Phe Asn Ile

85 90 95Ser Gly Asn Val Phe Phe Ser Phe Glu Glu Ser Pro Lys Asp Leu Lys

100 105 110Ala Ile Lys Glu Arg Leu Lys Lys Thr Ile Glu Pro Asn Thr Asp Pro

115 120 125Lys Ala Val Met Arg Phe Leu Asn Leu Gln Ala Ser Leu Ile Leu Glu

130 135 140Cys Val Pro Gln Thr Ala Cys Pro Phe Asp Thr Leu Leu Ile Pro Thr145 150 155 160Ala Leu Ser Val Pro Ile Asp Tyr Ala Asn Arg Leu Gly Asp Asn Pro

165 170 175Ser Leu Phe Pro Gln Glu Asp Lys Ser Tyr His Asn Ala Leu Ile Lys

180 185 190Ala Leu Asn Lys Ala Tyr Tyr Ser Leu Met Glu Gly Leu Glu Lys Arg

195 200 205Leu Asn Ala Ile Glu Asn Ala Ala Trp Leu

210215 (2) SEQ ID NO 503 information

Sequence properties:

(A) length: 124 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 124

(xi) sequence representation: 503 SEQ ID NO: Thr Ile Gln Glu Arg Leu Tyr Arg His Glu Ile Ser Arg Leu Gln Val 151015 Lys Thr Asp Glu Thr Leu Lys Leu Ile Lys Glu Ala Lys Lys Arg Leu

20 25 30Asn Tyr Asn Asp Asp Ile Arg Asp Val Leu Gln Gly Leu Leu Asn Ile

35 40 45Val Pro Asp Leu Ile Thr Ile Asn Ser Ile Glu Ile Asp Gln Gln Ser

50 55 60Val Val Val Ser Gly Lys Thr Pro Ser Lys Glu Ala Phe Tyr Phe Leu65 70 75 80Phe Gln Asn Lys Leu Asn Pro Met Phe Asp Tyr Ser Arg Ala Glu Phe

85 90 95Phe Pro Leu Ser Asp Gly Trp Phe Asn Phe Val Ser Thr Asn Phe Ser

100 105 ll0Asn Ser Leu Leu Ile Lys Asn Pro Glu Ser Ile Lys

115120 (2) SEQ ID NO 504 message

Sequence properties:

(A) length: 378 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 378

(xi) sequence representation: 504: Ile Ser Ile Glu Gln Thr Asn Lys Val Val Tyr Ala Lys Glu Ala Ala 151015 Ile Ser Ala Ala Ser Leu Gly Asp Ile Lys Thr Ala Met His Leu Ala SEQ ID NO

20 25 30 Met Leu Tyr Gln Lys Ile Thr Asn Asn Arg Asn Asp Val Ser Ile Asn

35 40 45Lys Ile Leu Val Asp Gly Tyr Ala Gln Met Gly Gln Ile Asp Lys Ala

50 55 60Ile Glu Leu Leu His Lys Ile Arg Lys Glu Glu Lys Thr Ile Ala Thr65 70 75 80Asp Asn Val Leu GlyThr Leu Tyr Leu Thr Gln Lys Arg Leu Asp Lys

85 90 95Ala Phe Pro Leu Leu Asn Lys Phe Tyr Asn Gln Val His Asp Glu Asp

100 105 110Ser Leu Glu Lys Leu Ile Thr Ile Tyr Phe Leu Gln Asn Arg Lys Lys

115 120 125Glu Gly Leu Val Leu Leu Gln Ser His Ile Asp Arg Tyr Gly Cys Ser

130 135 140Glu Gln Leu Cys Gln Lys Ala Leu Asn Thr Phe Thr Gln Phe Asn Glu145 150 155 160Leu Asp Leu Ala Lys Thr Thr Phe Ala Arg Leu Tyr Glu Lys Asn Pro

165 170 175Ile Val Gln Asn Ala Gln Phe Tyr Ile Gly Val Leu Ile Leu Leu Lys

180 185 190Glu Phe Asp Lys Ala Gln Gln Ile Ala Glu Leu Phe Pro Phe Asp Arg

195 200 205Arg Leu Leu Leu Asp Leu Tyr Thr Ala Gln Lys Lys Phe Asp Gln Ala

210 215 220Ser Lys Gln Ala Ser Leu Ile Tyr Gln Glu Arg Lys Asp Pro Lys Phe225 230 235 240Leu Gly Leu Glu Ala Ile Tyr His Tyr Glu Ser Leu Ser Ala Asn Lys

245 250 255Lys Lys Leu Thr Lys Glu Glu Met Leu Pro Ile Ile Gln Lys Leu Glu

260 265 270Gln Ala Thr Lys Glu Arg Gln Ala Trp Leu Ala Lys Thr Lys Asp Lys

275 280 285Glu Asp Ala Gln Asp Ala Phe Phe Tyr Asn Phe Leu Gly Tyr Ser Leu

290 295 300Ile Asp Tyr AspMet Asp Val Lys Arg Gly Met Asp Leu Val Arg Lys305 310 315 320Ala Leu Ala Leu Asp Ser Asn Ser Val Leu Tyr Leu Asp Ser Leu Ala

325 330 335Trp Gly Tyr Tyr Lys Leu Gly Asn Cys Leu Glu Ala Lys Lys Ile Phe

340 345 350Ser Ser Ile Ala Lys Glu Leu Ile Gln Asn Glu Pro Glu Leu Lys Glu

355 360 365His Asn Lys Ile Ile Gln Glu Cys Lys Lys

370375 (2) SEQ ID NO 505 information

Sequence properties:

(A) length: 156 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 156

(xi) sequence representation: 505: Phe Tyr Thr Gly Lys Lys Gly Ala Cys Met Arg Lys Ile Leu Leu Met 151015 Gly Leu Ile Leu Gln Ala Leu Phe Gly Glu Glu Thr Ala Gln Glu Leu SEQ ID NO

20 25 30Leu Gln Cys Ser Ala Ile Phe Glu Ser Lys Lys Ala Glu Leu Lys Glu

35 40 45Asp Leu Arg Gln Leu Ser Glu Lys Glu Gln Ser Leu ArG Ile Leu Gln

50 55 60Thr Glu Asn Ala Arg Leu Leu Asp Glu Lys Ser Asp Leu Leu Asn Lys6570 75 80Lys Glu Lys Glu Ile Asp Glu Lys Leu Lys Asn Leu Ala Ala Lys Glu

85 90 95Glu Ala Phe Lys Thr Leu Gln Thr Glu Glu Lys Lys Arg Leu Lys Asn

100 105 110Leu Ile Glu Glu Asn Glu Gly Ile Leu Arg Glu Ile Lys Gln Ala Lys

115 120 125Asp Ser Lys Ile Gly Glu Thr Tyr Ser Lys Met Lys Asp Ser Lys Ser

130135140 Ala Leu Ile Leu Glu Asn Leu Pro Thr Gln Asn Ala 145150155 (2) SEQ ID NO:506 information

Sequence properties:

(A) length: 141 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 141

(xi) sequence representation: SEQ ID NO 506: Lys Arg Leu Cys Asp Arg Leu Trp Ser Gly Gly Tyr Tyr Leu Ser Val 151015 Glu Arg Arg Asn Val Met Gly Val Ala Val Val Leu Phe Leu Thr Leu

20 25 30Ile Leu Leu Phe Leu Val Leu Arg Asp Phe Gly Leu Ala Ser Pro Lys

35 40 45Gln Lys Ile Leu Ala Phe Leu Ile Val Gly Ile Ile Gly Ala Ser Ile

50 55 60Ser Val Tyr Thr Tyr Lys Gln Asn Gln Gln Asn Gln Gln Glu Ile Ala6570 75 80Leu Gln Arg Ala Phe Leu Arg Gly Glu Thr Leu Leu Cys Lys Gly Ile

85 90 95Lys Val Asn Asn Gln Thr Phe Asn Leu Val Ser Gly Thr Leu Ser Phe

100 105 110Leu Gly Lys Lys Gln Thr Pro Met Lys Asp Val Leu Val Asp Leu Asp

115 120 l25Ser Cys Gln Thr Leu Gln Lys Asp Pro Leu Ile Gln Pro

130135140 (2) SEQ ID NO 507 information

Sequence properties:

(A) length: 100 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 100

(xi) sequence representation: 507 SEQ ID NO: Ala Lys Asn Thr Ile Phe Asn Asn Ala Asn Phe Asn Asn Ser Thr Ser 151015 Phe Asn Phe Asn Asn Ser Ser Ala Thr Thr Ser Phe Val Gly Asp Phe

20 25 30Thr Asn Ala Asn Ser Asn Leu Gln Ile Ala Gly Asn Ala Val Phe Gly

35 40 45Asn Ser Thr Asn Gly Ser Gln Asn Thr Ala Asn Phe Asn Asn Thr Gly

50 55 60Ser Val Asn Ile Ala Gly Asn Ala Thr Phe Asp Asn Val Val Phe Asn65 70 75 80Ser ProThr Asn Thr Gly Val Lys Gly Lys Val Thr Leu Asn Asn Ile

85 90 95Thr Leu Lys Thr

100(2) SEQ ID NO 508 information

Sequence properties:

(A) length: 123 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 123

(xi) sequence representation: 508: Trp Ala Met Asn Val Trp Val Tyr Arg Pro Leu Leu Ala Phe Met Asp 151015 Asn Arg Gln Ala Glu Ile Lys Asp Ser Leu Ala Lys Ile Lys Thr Asp SEQ ID NO

20 25 30Asn Thr Gln Ser Val Glu Ile Gly His Gln Ile Glu Thr Leu Leu Lys

35 40 45Glu Ala Ala Glu Lys Arg Arg Glu Met Leu Ala Glu Ala Ile Gln Lys

50 55 60Ala Thr Glu Ser Tyr Asp Ala Val Ile Lys Gln Lys Glu Asn Glo Leu65 70 75 80Asn Gln Glu Phe Glu Ala Phe Ala Lys Gln Leu Gln Asn Glu Lys Gln

85 90 95Ile Leu Lys Glu Gln Leu Gln Ala Gln Met Thr Val Phe Glu Asp Glu

100 105 110Leu Asn Lys Arg Val Ala Met Gly Leu Gly Ser

115120(2) SEQ ID NO 509 information

Sequence properties:

(A) length: 103 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 103

(xi) sequence representation: 509: Lys Gly Gly Phe Ile Ser Ala Lys Ser Cys Leu Ser Met Ala Ser Gly 151015 Leu Phe Glu Asn Asp Glu Ile Lys Asn Asn Lys Ala Arg Asp Phe Phe SEQ ID NO

20 25 30Tyr Ser His Ser Ser Leu Ile Val Phe Phe Leu Leu Leu Leu Gly Phe

35 40 45Gly Tyr Tyr Leu Gly Lys Leu Leu Phe Gly Gly Ser Ser Leu Glu Val

50 55 60Tyr Leu Asp Leu Arg Asp Lys His Glu Arg Leu Gln Gln Glu Ile Thr65 70 75 80Glu Leu Gln Ser Lys Asn Val Arg Leu Gln Lys Arg Leu Phe Glu Leu

85 90 95Arg Glu Leu Arg Pro Arg Asp

100(2) SEQ ID NO 510 information

Sequence properties:

(A) length: 332 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 332

(xi) sequence representation: 510: Leu Tyr Tyr Asn Ser Gln Leu Asn Trp Gly Phe Thr Asp Leu Ser Leu 151015 Cys Glu Leu Trp Leu Ser Phe Val Arg Asn Glu Met Ile Lys Ser Trp SEQ ID NO

20 25 30Thr Lys Lys Trp Phe Leu Ile Leu Phe Leu Met Ala Ser Cys Phe Gly

35 40 45His Leu Val Ala Thr Thr Gly Glu Lys Tyr Phe Lys Met Ala Asn Gln

50 55 60Ala Leu Lys Arg Gly Asp Tyr His Arg Ala Val Ala Phe Tyr Lys Arg65 70 75 80Ser Cys Asn Leu Arg Met Gly Val Gly Cys Thr Ser Leu Gly Ser Met

85 90 95Tyr Glu Tyr Gly Asp Gly Val Asp Gln Asn Ile Ser Lys Ala Val Phe

100 105 110Tyr Tyr Arg Arg Gly Cys Asn Leu Arg Asn Tyr Leu Ala Cys Ala Ser

115 120 125Leu Gly Ser Met Tyr Glu Asp Gly Asp Gly Val Gln Lys Asp Phe Pro

130 135 140Lys Ala Ile Tyr Tyr Tyr Arg Arg Gly Cys His Leu Lys Gly Gly Val145 150 155 160Ser Cys Gly Ser Leu Gly Phe Met Tyr Phe Asn Gly Thr Gly Val Lys

165 170 175Gln Asn Tyr Ala Lys Ala Leu Ser Phe Ser Lys Tyr Ala Cys Ser Leu

180185 190Asn Tyr Gly Ile Ser Cys Asn Phe Val Gly Tyr Met Tyr Lys Ser Ala

195 200 205Lys Gly Val Glu Lys Asp Leu Lys Lys Ala Leu Ala Asn Phe Lys Arg210 215 220Gly Cys His Leu Lys Asp Gly Ala Ser Cys Val Ser Leu Gly Tyr Leu225 230 235 240Tyr Glu Ala Gly Met Asp Val Lys Gln Asn Glu Glu Gln Ala Leu Asn

245 250 255Leu Tyr Lys Lys Gly Cys Ser Leu Lys Glu Gly Ser Gly Cys His Asn

260 265 270Val Ala Val Met Tyr Tyr Thr Gly Lys Gly Ala Pro Lys Asp Leu Glu

275 280 285Lys Ala Thr Ser Tyr Tyr Lys Lys Gly Cys Ala Leu Gly Phe Ser Gly

290 295 300Ser Cys Lys Val Leu Glu Val Ile Gly Lys Glu Ser Asp Asn Leu Gln305 310 315 320Asp Asp Ala Gln Asn Asp Thr Gln Asp Ser Val Gln

325330 (2) SEQ ID NO 511 information

Sequence properties:

(A) length: 94 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 94

(xi) sequence representation: SEQ ID NO 511: Ile Lys Val Arg Ser Val Lys Lys Thr Glu Arg Gly Leu Leu Ile Glu 151015 Lys Phe Thr Ser Gln Gly Glu Leu Val Pro Leu Glu Ile Val Val Glu

20 25 30Thr Ile Leu Ser Glu Ile Lys Ser Ser Ser Lys Gly Ile Ile Leu Ile

35 40 45Asp Gly Tyr Pro Arg Ser Val Glu Gln Met Gln Ala Leu Asp Lys Glu

50 55 60Leu Asn Ala Pro Asn Glu Val Ile Leu Lys Ser Val Ile Glu Val Glu65 70 75 80Val Ser Glu Asn Thr Ala Lys Glu Arg Val Leu Gly Gln Phe

8590 (2) SEQ ID NO 512 message

Sequence properties:

(A) length: 113 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 113

(xi) sequence representation: 512: His Phe Val Phe Arg Gly Asp Phe Cys Trp Ala Tyr Arg Tyr Tyr Ser 151015 Ile Asp Lys Glu Arg Glu Thr Gln Arg His Asp Ser Ser Tyr Ile Val SEQ ID NO

20 25 30Ile Asp Glu Leu Val Gly Met Cys Leu Ala Met Ala Ile Asn Gly Leu

35 40 45Ser Leu Val Gly Val Ile Leu Ser Phe Ile Phe Leu Gly Cys Tyr Asp

50 55 60Ile Thr Lys Pro SerLeu Ile Gly Lys Ile Asp Lys Glu Val Lys Gly65 70 75 80Gly Leu Gly Val Val Ala Asp Asp Ala Leu Ala Gly Val Leu Ala Gly

85 90 95Leu Ser Thr Leu Leu Ala Ile Asn Ile Leu Gly Phe Phe Asn Ile Lys

100105110 Phe (2) SEQ ID NO 513 information

Sequence properties:

(A) length: 79 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 79

(xi) sequence representation: 513: Met Trp Pro Val Ala Leu Lys Gln Pro Asn Arg Val Ser His Mis Phe 151015 Tyr Ile Met Ala Met Leu Phe Ile Leu Phe Asp Val Glu Ile Val Phe SEQ ID NO

20 25 30Met Phe Pro Trp Ala Ile Asp Phe Lys Lys Leu Gly Leu Phe Gly Leu

35 40 45Val Glu Met Leu Gly Phe Val Phe Phe Leu Ala Ile Gly Phe Ile Tyr

505560 Ala Leu Lys Arg Asn Ala Leu Ser Trp Gln Lys Leu Glu Val Lys 657075 (2) SEQ ID NO:514 information

Sequence properties:

(A) length: 60 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 60

(xi) sequence representation: 514: Phe Asp Leu Gly Val Arg Thr Asn Phe Ala Lys Thr Asn Phe Asn Lys 151015 His Arg Leu Asp Gln Gly Ile Glu Phe Gly Val Lys Ile Pro Val Ile SEQ ID NO

20 25 30Ala His Lys Tyr Phe Ala Thr Gln Gly Ser Ser Ala Ser Tyr Met Arg

35 40 45Asn Phe Ser Phe Ile Cys Gly Leu Phe Ser Arg Phe

505560 (2) SEQ ID NO 515 information

Sequence properties:

(A) length: 148 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 148

(xi) sequence representation: SEQ ID NO 515: Phe Gly Ser Arg Ala Phe Arg Arg Ile Phe Thr Lys Trp Gly Glu Arg 151015 Asp Phe Arg Lys Gly Ala Val Val Leu Met Arg Leu Leu Ile Ala Leu

20 25 30Val Leu Phe Leu Trp Trp Leu Asn Leu Gly Ala Lys Glu Ala Asp Phe

35 40 45Ile Ser Asp Trp Glu Tyr Gly Leu Ala Leu Tyr Lys Asn Pro Arg Gly

50 55 60Val Ala Cys Ala Lys Cys Mis Gly Ile Lys Gly Glu Gln Gln Glu Ile65 70 75 80Thr Phe Tyr Tyr Glu Lys Gly Glu Lys Lys Ile Leu Tyr Ala Pro Lys

85 90 95Ile Asn His Leu Asp Phe Lys Thr Phe Lys Asp Ala Leu Ser Leu Gly

100 105 110Phe Cys Met Met Pro Thr Tyr Asn Leu Asn Leu Glu Glu Ile Gln Ala

115 120 125Ile Tyr Leu Tyr Ile Thr Ser Leu Gly His Lys Asp Glu Arg Lys Asp

130135140 Pro Ser Lys Pro145(2) SEQ ID NO:516 information

Sequence properties:

(A) length: 172 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 172

(xi) sequence representation: 516: Lys Asn Arg His Lys Leu Leu Tyr Leu Leu Leu Lys Ash Leu Asn Phe 151015 Leu Lys Thr Ile Ser Thr Ile Phe Thr Gln Lys Arg Val Ile Ile Arg SEQ ID NO

20 25 30Ser Gln Gln Gly Phe Ser Cys Tyr Leu Asn Leu Lys Val Lys Thr Met

35 40 45Lys Lys Leu Ala Ala Leu Phe Leu Val Ser Ala Leu Gly Val Met Ser

50 55 60Leu Asn Ala Trp Glu Gln Thr Leu Lys Ala Asn Asp Leu Glu Val Lys65 70 75 80Ile Lys Ser Val Gly Asn Pro Ile Lys Gly Asp Asn Thr Phe Val Leu

85 90 95Ser Pro Thr Leu Lys Gly Lys Ala Leu Glu Lys Ala Ile Val Arg Val

100 105 110Gln Phe Met Met Pro Glu Met Pro Gly Met Pro Ala Met Lys Glu Met

115 120 125Ala Gln Val Ser Glu Lys Asn Gly Leu Tyr Glu Ala Lys Thr Asn Leu

130 135 140 Ser Met Asn Gly Thr Trp Gln Val Arg Val Asp Ile Lys Ser Lys Glu145 150 155 160Gly Gln Val Tyr Arg Thr Lys Thr Ser Leu Asp Leu

165170 (2) information SEQ ID NO 517

Sequence properties:

(A) length: 74 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 74

(xi) sequence representation: 517: Cys Leu Phe ValLeu Thr Lys Ser Gln Arg Ile Arg Met Lys Arg Leu 151015 Leu Leu Leu Ala Leu Ala Leu Phe Phe Ser Leu Ser Cys Thr Asn Ala SEQ ID NO

20 25 30Gln Glu Ile Lys Glu Thr Gln Glu Thr Lys Lys Thr Lys Glu Thr Lys

35 40 45Ser Gln Thr Arg Phe Asn Ile Ser Thr Thr Lys Val Ile Glu Lys Glu

505560 Phe Ser Gln Ser Arg Arg Tyr Tyr Ala Leu 6570 (2) SEQ ID NO:518 information

Sequence properties:

(A) length: 293 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 293

(xi) sequence representation: 518: Ile Lys Phe Ala Lys Lys Ile Val Leu Ile Leu Lys Lys Gly Gly Phe 151015 Met Lys Thr Asn Gly Leu Phe Lys Met Trp Gly Leu Phe Leu Val Leu SEQ ID NO

20 25 30Ile Ala Leu Val Phe Asn Ala Cys Ser Asp Ser His Lys Glu Lys Lys

35 40 45Asp Ala Leu Glu Val Ile Lys Gln Arg Gly Val Leu Lys Val Gly Val

50 55 60Phe Ser Asp Lys Pro Pro Phe Gly Ser Val Asp Ser Lys Gly Asn Tyr65 70 75 80Gln Gly Tyr Asp Val Val Ile Ala Lys Arg Met Ala Leu Asp Leu Leu

85 90 95Gly Asp Glu Asn Lys Ile Glu Phe Ile Pro Val Glu Ala Ser Ala Arg

100 105 110Val Glu Phe Leu Lys Ala Asn Lys Val Asp Ile Ile Met Ala Asn Phe

115 120 125Thr Arg Thr Lys Glu Arg Glu Lys Val Val Asp Phe Ala Asn Pro Tyr

130 135 140Met Lys Val Ala Leu Gly Val Ile Ser Lys Asp Gly Val Ile Lys Asn145 150 155 160Ile Glu Glu Leu Lys Asp Lys Glu Leu Ile Val Asn Lys Gly Thr Thr

165 170 175Ala Asp Phe Tyr Phe Thr Lys Asn Tyr Pro Asn Ile Lys Leu Leu Lys

180 185 190Phe Glu Gln Asn Thr Glu Thr Phe Leu Ala Leu Leu Asn Asn Lys Ala

195 200 205Ile Ala Leu Ala His Asp Asn Thr Leu Leu Leu Ala Trp Val Lys Gln

210 215 220His Pro Glu Phe Lys Leu Gly Ile Thr Ser Leu Gly Asp Lys Asp Val225 230 235 240Ile Ala Pro Ala Ile Lys Lys Gly Asn Pro Lys Leu Leu Glu Trp Leu

245 250 255Asn Asn Glu Ile Asp Ser Leu Ile Ser Ser Asp Phe Leu Lys Glu Ala

260 265 270Tyr Gln Glu Thr Leu Glu Pro Ile Tyr Gly Asp Gly Ile Lys Pro Glu

275 280 285Glu Ile Ile Phe Glu

290(2) SEQ ID NO 519 information

Sequence properties:

(A) length: 676 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 676

(xi) sequence representation: 519 ID NO: Ala Phe Glu Glu Leu Glu Pro Leu Ser Phe Ser Phe Asn Ser Pro Lys 151015 Gly Ala Cys Glu Ser Cys Leu Gly Leu Gly Thr Lys Phe Ser Leu Asp

20 25 30Ile Ser Lys Ile Leu Asp Pro Asn Thr Pro Leu Asn Gln Gly Ala Ile

35 40 45Lys Val Ile Phe Gly Tyr Asn Arg Ser Tyr Tyr Ala Gln Met Phe Glu

50 55 60Gly Phe Cys Thr Tyr Asn Gly Ile Asp Ser Ala Leu Cys Phe Asn Glu65 70 75 80Leu Asn Lys Glu Gln Gln Asp Ala Leu Leu Tyr Gly Asn Gly Thr Glu

85 90 95Ile Ser Phe His Phe Lys Asn Ser Pro Leu Lys Arg Pro Trp Lys Gly

100 105 110Ile Ile Gln Ile Ala Tyr Asp Met Phe Lys Glu Gln Lys Asp Leu Ser

115 120 125Asp Tyr Met Ser Glu Lys Thr Cys Ser Ser Cys Asn Gly His Arg Leu

130 135 140Lys Ala Ser Ser Leu Ser Val Gln Val Ala Gly Leu Lys Met Ala Asp145 150 155 160Phe Leu Thr Lys Pro Ile Glu Glu Val Tyr His PhePhe Asn Asp Pro

165 170 175Thr His Phe Asn Tyr Leu Asn Glu Gln Glu Lys Lys Ile Ala Glu Pro

180 185 190Ile Leu Lys Glu Ile Leu Glu Arg Val Phe Phe Leu Tyr Asp Val Gly

195 200 205Leu Gly Tyr Leu Thr Leu Gly Arg Asp Ala Arg Thr Ile Ser Gly Gly

210 215 220Glu Ser Gln Arg Ile Arg Ile Ala Ser Gln Ile Gly Ser Gly Leu Thr225 230 235 240Gly Val Leu Tyr Val Leu Asp Glu Pro Ser Ile Gly Leu His Glu Lys

245 250 255Asp Thr Leu Lys Leu Ile Asn Thr Leu Arg Asn Leu Gln Lys Lys Gly

260 265 270Asn Thr Leu Ile Val Val Glu His Asp Lys Glu Thr Ile Lys His Ala

275 280 285Asp Phe Val Val Asp Ile Gly Pro Lys Ala Gly Arg His Gly Gly Glu

290 295 300Val Val Phe Ser Gly Ser Val Lys Asp Leu Leu Gln Asn Asn His Ser305 310 315 320Thr Ala Leu Tyr Leu Asn Gly Thr Lys Lys Ile Glu Arg Pro Lys Phe

325 330 335Glu Pro Pro Lys Glu Lys His Phe Leu Glu Ile Lys Asn Val Asn Ile

340 345 350Asn Asn Ile Lys Asn Leu Ser Val Gln Ile Pro Leu Lys Gln Leu Val

355 360 365Cys Ile Thr Gly Val Ser Gly Ser Gly Lys Ser Ser Leu Ile Leu Gln

370 375 380Thr Leu Leu Pro Thr Ala Gln Thr Leu Leu Asn His Ala Lys Lys Asn385390 395 400Gln Ser Leu Asn Gly Val Glu Ile Val Gly Leu Glu Tyr Leu Asp Lys

405 410 415Val Ile Tyr Leu Asp Gln Ala Pro Ile Gly Lys Thr Pro Arg Ser Asn

420 425 430Pro Ala Thr Tyr Thr Gly Val Met Asp Glu Ile Arg Ile Leu Phe Ala

435 440 445Glu Gln Lys Glu Ala Lys Ile Leu Gly Tyr Ser Thr Ser Arg Phe Ser

450 455 460Phe Asn Val Lys Gly Gly Arg Cys Glu Lys Cys Gln Gly Asp Gly Asp465 470 475 480Ile Lys Ile Glu Met His Phe Leu Pro Asp Val Leu Val Gln Cys Asp

485 490 495Ser Cys Lys Gly Ala Lys Tyr Asn Pro Gln Thr Leu Glu Ile Lys Val

500 505 510Lys Gly Lys Ser Ile Ala Asp Val Leu Asn Met Ser Val Glu Glu Ala

515 520 525Tyr Glu Phe Phe Ala Lys Phe Pro Lys Ile Ala Val Lys Leu Lys Thr

530 535 540Leu Ile Asp Val Gly Leu Gly Tyr Ile Thr Leu Gly Gln Asn Ala Thr545 550 555 560Thr Leu Ser Gly Gly Glu Ala Gln Arg Ile Lys Leu Ala Lys Glu Leu

565 570 575Ser Lys Lys Asp Thr Gly Lys Thr Leu Tyr Ile Leu Asp Glu Pro Thr

580 585 590Thr Gly Leu His Phe Glu Asp Val Asn His Leu Leu Gln Val Leu His

595 600 605Ser Leu Val Ala Leu Gly Asn Ser Met Leu Val Ile Glu His Asn Leu

610 615 620Asp Ile Ile Lys Asn Ala Asp Tyr Ile Ile Asp Met Gly Pro Asp Gly625 630 635 640Gly Asp Lys Gly Gly Lys Val Ile Ala Ser Gly Thr Pro Leu Glu Val

645 650 655Ala Gln Asn Cys Glu Lys Thr Gln Ser Tyr Thr Gly Lys Phe Leu Ala

660 665 670Leu Glu Leu Lys

675(2) SEQ ID NO 520 information

Sequence properties:

(A) length: 138 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 138

(xi) sequence representation: 520: Ile Ile Ile Asp Tyr Ser Ser Gln Tyr Phe Ser Gly Arg Ala Ala Ala 151015 Phe Tyr Gln Ala Leu Asp Asn Phe Ile Ser Arg Tyr Ala Gln Arg Leu SEQ ID NO

20 25 30Ile Val Thr Asn Leu Ser Gln Ala Ile Arg Ile Tyr Gly Tyr Glu Val

35 40 45Gly Gly Thr Phe Arg Tyr Lys Gly Val Ser Leu Asn Val Gly Ile Ser

50 55 60Arg Thr Trp Pro Thr Thr Arg Gly Tyr Leu Met Ala Asp Ser Tyr Glu65 70 75 80Leu Ala Ala Ser Thr Gly Asn Val Phe Ile Ile Lys Leu Asp Tyr Thr

85 90 95Ile Ser Lys Asn Arg Asp Gln Ser Cys Met Ala Leu Ala Ala Leu Leu

100 105 110Pro Val Trp Ile Ile Ala Gly Leu Ile Phe Thr Cys Leu Ile Met Gly

115 120 125Gln Leu Lys Asn Pro Lys Pro Leu Pro Ile

130135 (2) SEQ ID NO 521 information

Sequence properties:

(A) length: 173 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 173

(xi) sequence representation: 52l Gln Gly Met Gly Leu Lys Asn Leu Ser Thr Leu Leu Val Phe Leu Phe 151015 Phe Cys Leu Gly Cys Val Ser Asn Phe Asn Glu Asp Thr Tyr Thr Leu SEQ ID NO

20 25 30Asp Leu Val Leu Glu Lys Lys Ile Gln Ala Ser Arg Lys Gly Glu Ile

35 40 45Thr Gln Asp Asn Val Pro Ile Ile Thr Ala Ile Ala Thr His Leu Asn

50 55 60Asp Val Asp Ser Gly Thr Tyr Tyr Asp His Glu Tyr Phe Leu Val Glu65 70 75 80Ile Phe Thr Gln Asn Asn Asp Trp Ile Asp Asp Gly Tyr Ile Ser Tyr

8590 95Glu Leu Phe Gly Thr Lys Pro Thr Gly Ser Glu Pro Leu Trp Val Arg

100 105 110Glu Ile Thr Arg Asp Glu Phe Asp Gly Ile Leu Glu Thr Thr Asn Arg

115 120 125Trp Ser Arg Ala Phe Leu Ile Ala Phe Asp Lys Leu Asp Tyr Leu Ala

130 135 140Val Gln Glu Ala Lys Leu Glu Leu Asp Ala Tyr Ser Leu Gly Lys Ile145 150 155 160Val Phe Asn Phe Ala Tyr Gln Val Pro Leu Pro Gln Phe

165170 (2) message SEQ ID NO 522

Sequence properties:

(A) length: 109 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 109

(xi) sequence representation: 522: Gln Lys Glu Val Ser Asn Tyr Glu Glu Ser Ile Leu Val Asn Thr Pro 151015 Tyr Ala Arg Val Asn Ile Leu Ala Ile Glu Lys Asn Glu Ser Pro Ile SEQ ID NO

20 25 30Glu Leu Leu Ala Pro Val Asp Leu Val Thr Ala Leu Ser Asp Leu Met

35 40 45Leu Gly Gly Glu Gly Ala Ser Lys Glu Glu Met Asp Asn Asp Asp Leu

50 55 60Asp Ala Phe Lys Glu Met Ala Ser AsnIle Phe Gly Ala Ile Ala Thr65 70 75 80Ser Leu Lys Ser Gln Glu Leu Leu Pro Lys Leu Asn Phe Thr Thr Thr

85 90 95Asn Ala Glu Ile Ala Lys Glu Leu Pro Lys Lys Glu Asp

100105 (2) information of SEQ ID NO:523

Sequence properties:

(A) length: 182 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 182

(xi) sequence representation: 523: Ile Cys Leu Leu Lys Glu Lys Ile Met Ser Asn Ser Met Leu Asp Lys 151015 Asn Lys Ala Ile Leu Thr Gly Gly Gly Ala Leu Leu Leu Gly Leu Ile SEQ ID NO

20 25 30Val Leu Phe Tyr Leu Ala Tyr Arg Pro Lys Ala Glu Val Leu Gln Gly

35 40 45Phe Leu Glu Ala Arg Glu Tyr Ser Val Ser Ser Lys Val Pro Gly Arg

50 55 60Ile Glu Lys Val Phe Val Lys Lys Gly Asp Arg Ile Lys Lys Gly Asp65 70 75 80Leu Val Phe Ser Ile Ser Ser Pro Glu Leu Glu Ala Lys Leu Ala Gln

85 90 95Ala Glu Ala Gly His Lys Ala Ala Lys Ala Val Ser Asp Glu Val Lys

100 105 110Arg Gly Ser Arg Asp Glu Thr Ile Asn Ser Ala Arg Asp Val Trp Gln

115 120 125Ala Ala Lys Ser Gln Ala Asn Leu Ala Lys Glu Thr Tyr Lys Arg Val

130 135 140Gln Asp Leu Tyr Asp Asn Gly Val Ala Ser Leu Gln Lys Arg Asp Glu145 150 155 160Ala Tyr Ala Ala Met Lys Ala Pro Asn Thr Thr Arg Ala Arg Leu Thr

165 170 175Lys Ser Ile Lys Trp Leu

180(2) SEQ ID NO 524 information

Sequence properties:

(A) length: 148 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 148

(xi) sequence representation: SEQ ID NO 524: Met Glu Phe Leu Ser Gly Tyr Phe Leu Trp Val Lys Ala Phe His Val 151015 Ile Ala Val Ile Ser Trp Met Ala Ala Leu Phe Tyr Leu Pro Arg Leu

20 25 30Phe Val Tyr His Ala Glu Asn Ala His Lys Lys Glu Phe Val Gly Val

35 40 45Val Gln Ile Gln Glu Lys Lys Leu Tyr Ser Phe Ile Ala Ser Pro Ala

50 55 60Met Gly Phe Thr Leu Ile Thr Gly Ile Leu Met Leu Leu Ile Ala Pro6570 75 80Glu Met Phe Lys Ser Gly Gly Trp Leu His Ala Lys Leu Ala Leu Val

85 90 95Val Leu Leu Leu Ile Tyr His Phe Tyr Cys Lys Lys Cys Met Arg Glu

100 105 110Leu Glu Lys Asp Pro Thr Gly Lys Asn Ala Arg Phe Tyr Arg Val Phe

115 120 125Asn Glu Ile Pro Thr Ile Leu Met Ile Leu Ile Val Ile Leu Val Val

130135140 Val Lys Pro Phe145(2) SEQ ID NO:525 information

Sequence properties:

(A) length: 291 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 291

(xi) sequence representation: SEQ ID NO 525: Gly Leu Thr Ile Arg Gln Ala Phe Asn Lys Thr Arg Ser Thr His Ser 151015 Arg Thr Leu Leu Leu Asp Ile Asp Cys Val Ile Pro Asn Ile Val Arg

20 25 30Arg Leu Leu Ser Asn Lys Thr Leu Pro Lys Arg Phe Ala Thr Tyr Ser

35 40 45Leu Gln Glu Val Gly Val Ile Phe Leu Thr Thr Gln Ile Leu Ser Ile

50 55 60Met Arg Lys Thr Arg Cys Ser Lys Thr Leu Phe Phe Ile Thr Arg Gly65 7075 80Arg Glu Ser Phe Arg Tyr Gln Leu Cys Asp His Tyr Lys Gln Lys Arg

85 90 95His Gln Phe Asp Glu Asp Phe Arg Ser Leu Leu Lys Ala Leu Lys Ile

100 105 110Ala Leu Val Glu Lys Tyr Pro Leu Lys Lys Gly Ala Lys Ile Gln Gly

115 120 125Glu His Cys Phe Glu Tyr Glu Ala Asp Asp Ile Ile Ser Phe Tyr Lys

130 135 140Lys Lys Asp Pro Asn Asn Tyr Val Ile Ala Ser Met Asp Lys Asp Ile145 150 155 160Leu Tyr Ser Asn Arg Gly Ser His Phe Asn Leu Lys Thr Asn Ala Phe

165 170 175Phe Asn Val Ser Gln Lys Glu Ala His Phe Phe Ala Tyr Tyr Gln Cys

180 185 190Val Val Gly Asp Lys Gly Asp Asn Ile Lys Gly Val Lys Gly Ile Gly

195 200 205Gly Phe Asn Tyr Lys Asp Phe Leu Asn Glu Asp Ala Lys Glu His Glu

210 215 220Leu Trp Glu Gln Ile Ile Gln Ala Phe Lys Ile Lys Glu Asp Leu Ser225 230 235 240Asp Ser Glu Ala Lys Glu Lys Ala Leu Leu Asn Met Arg Leu Val Asn

245 250 255Met His Gln Met Thr His His Gly Val Ile Lys Leu Trp Glu Pro Glu

260 265 270Phe Lys Lys Ala Phe Phe Pro Lys Lys Pro Gln Arg Pro Asp Phe Lys

275 280 285Arg Ile Ser

290(2) SEQ ID NO 526 information

Sequence properties:

(A) length: 193 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 193

(xi) sequence representation: 526 SEQ ID NO: Gly Val Tyr His Asn Lys Glu Ile Ile Val Ala Tyr Arg Lys Ile Gly 151015 Lys Val His Ser Thr Leu Thr Thr Thr Ser Met Ile Leu Ala Phe Gly

20 25 30Val Gln Lys Val Leu Phe Ser Gly Val Ala Gly Ser Leu Val Lys Asp

35 40 45Leu Lys Ile Asn Asp Leu Leu Val Ala Thr Gln Leu Val Gln His Asp

50 55 60Val Asp Leu Ser Ala Phe Asp His Pro Leu Gly Phe Ile Pro Glu Ser65 70 75 80Ala Ile Phe Ile Glu Thr Ser Gly Ser Leu Asn Ala Leu Ala Lys Lys

85 90 95Ile Ala Asn Glu Gln His Ile Ala Leu Lys Glu Gly Val Ile Ala Ser

100 105 110Gly Asp Gln Phe Val His Ser Lys Glu Arg Lys Glu Phe Leu Val Ser

115 l20 125Glu Phe Lys Ala Ser Ala Val Glu Met Glu Gly Ala Ser Val Ala Phe

130 135 140Val Cys Gln Lys Phe Gly Val Pro Cys Cys Val Leu Arg Ser Ile Ser145150 155 160Asp Asn Ala Asp Glu Lys Ala Gly Met Ser Phe Asp Glu Phe Leu Glu

165 170 175Lys Ser Ala His Thr Ser Ala Lys Phe Leu Lys Ser Met Val Asp Glu

180185190 Leu (2) SEQ ID NO 527 message

Sequence properties:

(A) length: 80 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 80

(xi) sequence representation: SEQ ID NO 527: Lys Leu Ala Leu Phe Lys Gln Arg Gln Leu Lys Gln Asn Lys Asn Ala 151015 Gln Ala Asn Pro Lys Ser Pro Phe Ile Thr His Val Val Leu Pro Lys

20 25 30Glu Thr Leu Ser Ser Ile Ala Lys Arg Tyr Gln Val Ser Ile Ser Ser

35 40 45Ile Gln Leu Ala Asn Asn Leu Lys Asp Ser Asn Ile Phe Ile His Gln

505560 Arg Leu Ile Ile Pro Thr Asn Lys Lys Leu Leu Ala Thr Arg Glu Phe 65707580 (2) SEQ ID NO:528 information

Sequence properties:

(A) length: 245 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 245

(xi) sequence representation: 528: Gly His Arg Lys Arg Ile Phe Ser Lys Pro Ala Leu Leu Arg Ala Leu 151015 Glu Pro Asn Glu Ala Leu Ile Phe Ser Gln Thr Leu Arg Phe Asp Gly SEQ ID NO

20 25 30Tyr Val Glu Lys Leu Tyr Ala Asn Lys Thr Tyr Thr Pro Ile Lys Lys

35 40 45Gly Asp Arg Leu Leu Ser Val Tyr Ser Pro Glu Leu Ala Gly Val Gln

50 55 60Ser Glu Leu Leu Ser Ser Leu Lys Phe Asn Gln Gln Val Gly Ala Ile65 70 75 80Lys Glu Lys Leu Lys Leu Leu Gly Leu Glu Asn Phe Ser Ile Glu Lys

85 90 95Ile Ile Ser Ser His Lys Val Gln Asn Glu Ile Thr Ile Tyr Ser Arg

100 105 110Phe Asn Gly Val Ile Pne Lys Lys Ser Pro Asp Leu Asn Glu Gly Ser

115 120 125Phe Ile Lys Lys Gly Gln Glu Leu Phe Lys Ile Ile Asp Leu Ser Arg

130 135 140Leu Trp Ala Leu Val Lys Val Asn Gln Glu Asp Leu Glu Phe Leu Lys145 150 155 160Asn Thr His Gln Ala Ile Leu Phe Val Glu Gly Val Lys Gly Lys Gln

165 170 175Ala Ile Thr Leu Glu Asn Ile Asn Pro Ile Ile Asn Ala Gln Asp Lys

180 185 190Met Leu Glu Ala Arg Phe Asn Val Pro Asn Leu Lys Leu Leu Tyr Tyr

195 200 205Pro Asn Met Phe Ala Gln Val Glu Ile Phe His Lys Pro Gln Lys Met

210 215 220Lys Ile Leu Pro Lys Glu Ala Val Leu Ile Lys Gly Gly Lys Ala Ile225 230 235 240Val Phe Lys Lys Asp

245(2) SEQ ID NO:529 information

Sequence properties:

(A) length: 152 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 152

(xi) sequence representation: SEQ ID NO 529: Ser Gly Glu Mis Thr Met Lys Lys Tyr Ile Leu Asn Leu Ala Leu Val 15l 015 Gly Ala Leu Ser Ala Ser Phe Leu Met Ala Lys Pro Ala His Asn Ala

20 25 30Asn Asn Ser Thr His Asn Thr Lys Glu Thr Thr Asp Ala Ser Ala Gly

35 40 45Val Leu Ala Thr Val Asp Gly Arg Pro Ile Thr Lys Ser Asp Phe Asp

50 55 60Met Ile Lys Gln Arg Asn Pro Asn Phe Asp Phe Asp Lys Leu Lys Glu65 70 75 80Lys Glu Lys Glu Ala Leu Ile Glu Gln Ala Ile Arg Thr Ala Leu Val

85 90 95Glu Asn Glu Ala Lys Ala Glu Lys Leu Asn Gln Thr Pro Glu Phe Lys

100 105 110Ala Met Met Glu Ala Val Lys Lys Gln Ala Leu Val Glu Phe Trp Ala

115 120 125Lys Lys Gln Ala Glu Glu Val Lys Lys Asp Pro Asn Pro Arg Lys Arg

130135140 Asn Ala Gly Phe Leu Gln Arg Gln 145150 (2) SEQ ID NO 530 information

Sequence properties:

(A) length: 184 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 184

(xi) sequence representation: 530: Arg Ala Leu Lys Thr His Gly Ala Leu Ala Phe Val Gln Ala Phe Leu 151015 Glu Ser Phe Lys Gly Phe Leu Ser Gln Ala Thr Leu Ile Ser Val Leu SEQ ID NO

20 25 30Ile Ala Ser Val Leu Ile Leu Phe Cys Ala Ile Leu Leu Leu Leu Ala

35 40 45Leu Leu Leu Arg Asn Arg Trp Ala Ser Tyr Ile Thr Thr Ala Ala Phe

50 55 60Leu Gly Ala Phe Leu Ser Met Pro Phe Val Leu Asn Val Leu Leu Thr65 70 75 80Gln Ala Ile Tyr Pro Ile Glu Thr Arg Ile Leu His Ala Asn Pro Leu

85 90 95Ser Tyr Ser Asn Ala Phe Ser Leu Gln Val Gly Val Lys Asn Ile Ser

100 105 110Lys Phe Ser Leu Asn Lys Cys Val Leu Arg Leu Glu Val Leu Lys Asn

115 120 125Pro His Asn Phe Val Glu Glu Arg Ala Phe Lys Trp Phe Val Lys Lys

130 135 140Ser Tyr Glu Lys Thr Phe Lys Glu Lys Ile Leu Pro Glu Glu Ser Lys145 150 155 160Val Phe Ser Phe Phe Ile Asp Asp Tyr Pro Tyr Ser Lys Thr Ala Pro

165 170 175Tyr Gln Val Ser Leu Phe Cys Leu

180(2) SEQ ID NO 531 information

Sequence properties:

(A) length: 115 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 115

(xi) sequence representation: SEQ ID NO 531: Ala Mer Asn Ile Lys Thr His Ser Ser Asn Glu Lys Glu Arg Phe Val 151015 Arg Ile Glu Glu Asp Glu Lys Lys Glu Leu Phe Ala Glu Ala Thr Asn

20 25 30Glu Asn Pro His Gly Leu Ser Leu Met Ala Leu Ile Gly Val Leu Val

35 40 45Phe Gly Gly Ala Phe Leu Ala Leu Leu Val Pro Lys Ile Tyr Leu Ser

50 55 60Asn Asn Ile Tyr Tyr Ile Ser Arg Lys Ile Asn Thr Leu Glu Asp Gln65 70 75 80Lys Arg Leu Leu Leu Glu Glu Gln Gln Ile Leu Lys Asn Glu Leu Glu

85 90 95Lys Glu Arg Phe Lys Tyr Tyr Ile Glu Asn Ser Glu Asn Ile Gly Asp

100 105 ll0Ile Ala Phe

115(2) SEQ ID NO:532 information

Sequence properties:

(A) length: 238 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 238

(xi) sequence representation: 532: Leu Leu Leu Ile His Phe Leu Ile Leu Arg Lys Leu Leu Gln His Lys 151015 Thr Ile Met Asp Lys Ile Ile Ile Gln Gly Ala Arg Glu Asn Asn Leu SEQ ID NO

20 25 30Lys Asn Ile Phe Leu Glu Ile Pro Lys Asn Gln Phe Val Val Phe Thr

35 40 45Gly Leu Ser Gly Ser Gly Lys Ser Thr Leu Ala Phe Asp Thr Lau Tyr

50 55 60Ala Glu Gly Gln Arg Arg Tyr Leu Glu Ser Leu Ser Ser Tyr Ala Arg65 7075 80Gln Phe Leu Asp Lys Val Gly Lys Pro Asn Val Asp Lys Ile Glu Gly

85 90 95Leu Thr Pro Ala Ile Ala Ile Asp Gln Lys Thr Thr Ser Lys Asn Pro

100 105 110Arg Ser Thr Val Gly Thr Ile Thr Glu Ile Tyr Asp Tyr Leu Arg Leu

115 120 125Leu Leu Ala Arg Val Gly Glu Gln Phe Cys Pro Thr Cys Leu Glu Pro

130 135 140Ile Ser Ser Met Ser Ala Ser Asp Ile Ile Ser Gln Ile Cys His Leu145 150 155 160Glu Glu Asn Ser Lys Ile Ile Ile Leu Ala Pro Ile Ile Lys Asp Lys

165 170 175Lys Gly Ser Phe Asn Asp Lys Leu Glu Ser Leu Arg Leu Lys Gly Tyr

180 185 190Val Arg Ala Phe Val Asp Gly Val Met Val Arg Leu Asp Glu Glu Ile

195 200 205His Leu His Lys Thr Lys Lys Mis Thr Ile Glu Ala Val Val Asp Arg

210215220 Val Val Ile Asn Ser Glu Asn Ala Ser Arg Ile Ala Ser Ala 225230235 (2) SEQ ID NO:533 information

Sequence properties:

(A) length: 361 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 361

(xi) sequence representation: 533 SEQ ID NO: His Gln Ser Phe Lys Arg Ala Phe Glu Pro Arg Arg Lys Gly Arg Val 151015 Phe Arg Ile Met Gly Phe Glu Lys Ser Ile Leu Asp Asn Leu Asn Gly

20 25 30Ala Gln Lys Ile Ala Ala Cys His Ile Gln Gly Pro Leu Leu Ile Leu

35 40 45Ala Gly Ala Gly Ser Gly Lys Thr Lys Thr Leu Thr Ser Arg Leu Ala

50 55 60Tyr Leu Ile Gly Ala Cys Gly Val Pro Ser Glu Asn Thr Leu Thr Leu65 70 75 80Thr Phe Thr Asn Lys Ala Ser Lys Glu Met Gln Glu Arg Ala Leu Lys

85 90 95Leu Leu Lys Asn Gln Ala Leu Ile Pro Pro Leu Leu Cys Thr Phe His

100 105 110Arg Phe Gly Leu Leu Phe Leu Arg Gln His Met Asn Leu Leu Lys Arg

115 120 125Ala Cys Asp Phe Ser Val Leu Asp Ser Asp Glu Val Lys Thr Leu Cys

130 135 140Lys Gln Leu Lys Ile Ser Asn Phe Arg Ala Ser Ile Ser Gln Ile Lys145 150 155 160Asn Gly Met Met Asp Leu Ser Val Gln Asp Ser Glu Cys Tyr Lys Ala

165 170 175Tyr Glu Leu Tyr Gln Asn Ala Leu Lys Lys Asp Asn Leu Val Asp Phe

180 185 190Asp Asp Leu Leu Cys Leu Ser Leu Lys Ile Leu Gln Asp Asn Glu Lys

195 200 205Leu Ala Lys Glu Thr Ser Glu Arg Tyr His Tyr Ile Met Val Asp Glu

210215 220Tyr Gln Asp Thr Asn Ala Leu Gln Leu Glu Phe Leu Lys Gln Leu Ser225 230 235 240Phe Thr His His Asn Leu Cys Val Val Gly Asp Asp Asp Gln Ser Ile

245 250 255Tyr Gly Phe Arg Gly Ala Asp Ile Ser Asn Ile Leu Asn Phe Ser Lys

260 265 270His Phe Lys Gly Ala Lys Ile Val Lys Leu Glu Thr Asn Tyr Arg Ser

275 280 285Ser Ala Glu Ile Leu Ala Cys Ala Asn Ser Leu Ile Ser His Asn Gln

290 295 300His Arg His Ile Lys Thr Leu Gln Ser Phe Lys Gly Ser His Lys Ser305 310 315 320Val Ile Cys Lys Glu Tyr Pro Thr Gln Lys Glu Glu Ser Leu Asp Val

325 330 335Ala Tyr Gln Ile Gln Ser Pro Phe Lys Glu Gly Arg Glu Phe Arg Lys

340 345 350Tyr Arg Tyr Phe Val Ser Phe Lys Trp

355360 (2) SEQ ID NO 534 information

Sequence properties:

(A) length: 152 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 152

(xi) sequence representation: SEQ ID NO 534: Met Arg Lys Thr Ile Ser Ala Leu Phe Leu Ser Ala Cys Ile Gly Leu 151015 Ser Ser Val His Ala Ser Asn Ala Leu Ile Leu Gln Thr Asp Phe Ser

20 25 30Leu Lys Asp Gly Ala Val Ser Ala Met Lys Gly Val Ala Phe Ser Val

35 40 45Asp Ser Asn Leu Lys Ile Phe Asp Leu Thr His Glu Ile Pro Pro Tyr

50 55 60Asn Ile Trp Glu Gly Ala Tyr Arg Leu Tyr Gln Thr Ala Ser Tyr Trp65 70 75 80Pro Lys Gly Ser Val Phe Val Ser Val Val Asp Pro Gly Val Gly Thr

85 90 95Asn Arg Lys Ser Val Val Leu Lys Thr Lys Asn Gly Gln Tyr Phe Val

100 105 110Ser Pro Asp Asn Gly Thr Leu Thr Leu Val Ala Gln Thr Leu Gly Ile

115 120 125Asp Ser Arg Ala Glu Ile Asp Glu Asn Ser lle Arg Leu Lys Gly Ser

130135140 Lys Phe Leu Ser Ser Arg Pro Val 145150 (2) SEQ ID NO:535 information

Sequence properties:

(A) length: 243 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 243

(xi) sequence representation: 535 SEQ ID NO: Asp Ile Phe Asn Lys Glu Glu Ile Met Ala Ile Asp Leu Ala Glu Val 15l 015 Thr Gly Ala Lys Ala Ala Gln Glu Arg Lys Lys Glu Gln Pro Thr Ile

20 25 30Ala Asn Gly Leu Asp Lys Asn Ala Phe Met Lys Leu Phe Leu Glu Gln

35 40 45Leu Lys Asn Gln Asp Pro Thr Ala Pro Met Glu Thr Asp Lys Ile Ile

50 55 60Thr Gln Thr Ala Gln Leu Thr Gln Val Glu Met Gln Glu Glu Asn Lys65 70 75 80Lys Thr Met Gln Glu Val Ala Ser Ala Met Lys Ser Asn Lys Glu Thr

85 90 95Asn Glu Ser Leu Lys Asp Phe Gln Gly Ala Leu Lys Asp Thr Met Glu

100 105 110Asn Leu Asn Lys Gly Met Asp Asp Ser Leu Lys Ala Asn Asn Ala Leu

115 120 125Arg Glu Val Ser Ala Leu Asn Ser Val Ser Met Ile Gly Lys Ile Ala

130 135 140Glu Thr Asp Val Ser Gly Ala Asn Phe Asp Gly Asn Asn Lys Leu Ser145 150 155 160Phe Ser Leu Phe Phe Asp Glu Lys Ile Asp Ala Ser Lys Gly Val Pro

165 170 175Ala Ile Gln Ile Leu Asn Glu Asn Asn Glu Leu Val Lys Thr Ile Pro

180 185 190Leu Lys Asp Tyr Asn Gly Gln Lys Gly Tyr Ile Asn Phe Glu Trp Asp

195 200 205Gly Thr Asn Glu Lys Gly Glu Lys Val Pro Lys Gly Asn Tyr Lys Ile

210215220 Lys Ala Glu Tyr Asn Leu Gly Ser Pro Lys Gln Ala Val Phe Ala Asn 225230235240 Ala HisTrp (2) SEQ ID NO:536 information

Sequence properties:

(A) length: 253 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 253

(xi) sequence representation: 536: Asn Ala His Ala Phe Thr His Pro Phe Ser Ala Pro Ala Arg Phe Arg 151015 Leu Ala Gln Lys Arg Lys Asp Asn Thr Leu Pro Phe Leu Arg Pro Asp SEQ ID NO

20 25 30Gly Lys Ser Gln Val Ser Val Arg Tyr Glu Asn Asn Lys Pro Val Ser

35 40 45Val Asp Thr Ile Val Ile Ser Thr Gln His Ser Pro Glu Val Ser Gln

50 55 60Lys His Leu Lys Glu Ala Val Ile Glu Glu Ile Val Tyr Lys Val Leu65 70 75 80Pro Lys Glu Tyr Leu His Asp Asn Ile Lys Phe Phe Ile Asn Pro Thr

85 90 95Gly Lys Phe Val Ile Gly Gly Pro Gln Gly Asp Ala Gly Leu Thr Gly

100 105 110Arg Lys Ile Ile Trp Asp Thr Tyr Gly Gly Phe Cys Pro His Gly Gly

115 120 l25Gly Ala Phe Thr Gly Lys Asp Pro Tyr Lys Val Asp Met Ser Ala Ala

130 135140Tyr Ala Ala ArG Tyr Val Ala Lys Asn Leu Val Ala Ser Gly Val Cys145 150 155 160Asp Lys Ala Thr Val Gln Leu Ala Tyr Ala Ile Gly Val Ile Glu Pro

165 170 175Val Ser Ile Tyr Val Asn Thr His Asn Thr Ser Lys His Ser Ser Ala

180 185 190Glu Leu Glu Lys Cys Val Lys Ser Val Phe Lys Leu Thr Pro Lys Gly

195 200 205Ile Ile Glu Ser Leu Asp Leu Leu Arg Pro Ile Tyr Ser Leu Thr Ser

210 215 220Ala Tyr Gly His Phe Gly Arg Glu Leu Glu Glu Phe Thr Trp Glu Lys225 230 235 240Thr Asn Lys Val Glu Glu Ile Lys Ala Phe Phe Lys Arg

2456250 (2) SEQ ID NO 537 information

Sequence properties:

(A) length: 65 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 65

(xi) sequence representation: 537: Val Ile Ser Tyr His Phe Ile Ile Leu Lys Asp Val Phe Ile Met Arg 151015 Ile Lys Ala Tyr Phe Leu Arg Leu Ser His Trp Phe Leu Ser Phe Gly SEQ ID NO

20 25 30Trp Val Leu Ala Leu Val Lys Thr Leu Lys Asn Leu Lys Ile Leu Lys

35 40 45Thr Ile Pro Pro Asn Lys Ile Ala Leu Lys Pro Thr Pro Tyr Gly Ser

505560 Glu65(2) SEQ ID NO:538 information

Sequence properties:

(A) length: 122 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 122

(xi) sequence representation: 538 SEQ ID NO: Lys Gly Ile Ser Met Lys Lys Ser Leu Cys Leu Ser Phe Phe Leu Thr 151015 Phe Ser Asn Pro Leu Gln Ala Leu Val Ile Glu Leu Leu Glu Glu Ile

20 25 30Lys Thr Ser Pro His Lys Gly Thr Phe Lys Ala Lys Val Leu Asp Ser

35 40 45Lys Glu Pro Arg Gln Val Leu Gly Val Tyr Asn Ile Ser Pro His Lys

50 55 60Lys Leu Thr Leu Thr Ile Thr His Ile Ser Thr Ala Ile Val Tyr Gln65 70 75 80Pro Leu Asp Glu Lys Leu Ser Leu Glu Thr Thr Leu Ser Pro Asn Arg

85 90 95Pro Thr Ile Pro Arg Asn Thr Gln Ile Val Phe Ser Ser Lys Glu Leu

100 105 110Lys Glu Pro His Ser Asn Pro Ile Pro Ser

115120 (2) SEQID NO 539 message

Sequence properties:

(A) length: 136 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 136

(xi) sequence representation: SEQ ID NO:539: Lys Lys Phe His Thr Leu Ile Leu Pro Val Glu Trp Gly Thr Glu Ile 151015 Val Leu Val Val Ser Gly Ser Leu Gln Asn Ile Val Arg Ser Phe Leu

20 25 30Arg Arg Ile Ser Val Phe Phe Ile Ile Asp Phe Ile Asn Phe Ile Phe

35 40 45Val Ile Asp Gln Ile Ile His Phe Phe Gly Asp Phe Phe Ile Phe Phe

50 55 60Phe Met Leu Asn Leu Phe Tyr Ile Leu Ile Arg Leu Ile Asp Leu Ile65 70 75 80Val Leu Ser Gly Phe Ser Val Val Leu Val Arg Leu Gly Gln Phe Phe

85 90 95Arg Leu Ile Phe Ala Cys Ala Gln His Ala Phe Asn Lys Val Asp Ile

100 105 110Asp Lys Met Ser Asp Phe Arg Phe His Gln Leu Ser Phe Phe Lys Ser

115 120 125Val Tyr Asn Leu Phe Ile Leu Ser

130135 (2) SEQ ID NO 540 information

Sequence properties:

(A) length: 69 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 69

(xi) sequence representation: 540: Tyr Phe Leu Leu Ser Gly Glu Leu Arg Leu Ser Trp Trp Leu Val Ala 151015 Arg Cys Lys Thr Leu Phe Val Leu Phe Cys Glu Gly Ser Ala Phe Ser SEQ ID NO

20 25 30Ser Leu Leu Ile Ser Ser Ile Leu Phe Ser Leu Leu Ile Arg Ser Phe

35 40 45Thr Ser Leu Val Thr Phe Ser Ser Ser Ser Ser Cys Ser Ile Phe Phe

505560 Ile Ser Leu Leu Gly65(2) SEQ ID NO 541 information

Sequence properties:

(A) length: 243 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 243

(xi) sequence representation: 541: Thr Leu Phe Lys Ser Ser Asp Lys Val Cys Asn Leu Met Arg Val Ile 151015 Ile Lys Phe Met Leu Ile Ser Leu Lys Thr Phe Leu Lys Ile Leu Leu SEQ ID NO

20 25 30Glu Ile Phe Leu Lys Thr Phe Gln Lys Ile Trp Ile Val Cys Val Val

35 40 45Ile Trp Gly Leu Gly Cys Ser Phe Leu Asn Ala Asn Ser Val Gln Leu

50 55 60Glu Glu Thr Leu Arg Arg Asn Pro Lys Asn Leu Ile Trp Gln His Phe65 70 75 80Lys Lys Lys Phe Lys Lys Ser Asn Thr Ile Pro Tyr Ala Pro Asn Ser

85 90 95Arg Trp Lys Tyr Leu Gly Thr Ser lle Gly Ile Leu Gly Val Ser Leu

100 105 110Val Ile Gly Ile Val Gly Leu Tyr Leu Met Pro Glu Ser Val Thr Asn

115 120 125Trp Asp Lys Glu Lys Phe Gly Val Lys Ser Trp Phe Glu Asn Val Arg

130 135 140Met Gly Pro Lys Leu Asp Asn Asp Ser Phe Ile Phe Asn Glu Ile Leu145 150 155 160His Pro Tyr Phe Gly Ala Met Tyr Tyr Met Gln Pro Arg Met Ala Gly

165 170 175Phe Ser Trp Met Thr Ser Ala Phe Phe Ser Phe Ile Thr Ser Thr Leu

180 185 190Phe Trp Glu Tyr Gly Leu Glu Pro Phe Val Glu Val Pro Ser Trp Gln

195 200 205Asp Leu Val Ile Thr Pro Leu Leu Gly Phe Ile Leu Gly Glu Gly Phe

210215220 Tyr Gln Leu Thr Pro Ile Ser Asn Ala Thr Lys Ala Ser Cys Leu Ala 225230235240 Leu Tyr Phe (2) SEQ ID NO:542 information

Sequence properties:

(A) length: 486 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 486

(xi) sequence representation: 542: Lys Lys Arg Lys Pro Met Phe Arg Lys Leu Ala Thr Ser Val Ser Leu 151015 Ile Ser Leu Leu Ile Ser Asn Ala Leu Tyr Ala Lys Glu Ile Ser Glu SEQ ID NO

20 25 30Ala Asp Lys Val Ile Lys Ala Thr Lys Glu Thr Lys Glu Thr Lys Lys

35 40 45Glu Ala Lys Arg Leu Lys Lys Glu Ala Lys Gln Arg Gln Gln Ile Pro

50 55 60Asp Asn Lys Lys Pro Gln Tyr Val Ser Val Asp Asp Thr Lys Thr Gln65 70 75 80Ala Leu Phe Asp Ile Tyr Asp Thr Leu Asn Val Asn Asp Lys Ser Phe

85 90 95Gly Asp Trp Phe Gly Asn Ser Ala Leu Lys Asn Lys Thr Tyr Leu Tyr

100 105 110Ala Met Asp Leu Leu Asp Tyr Asn Asn Tyr Leu Ser Ile Glu Asn Pro

115 120 125Ile Ile Lys Thr Arg Ala Met Gly Thr Tyr Ala Asp Leu Ile Ile Ile

130 135 140Thr Gly Ser Leu Glu Gln Val Asn Gly Tyr Tyr Asn Ile Leu Lys Ala145150 155 160Leu Asn Lys Arg Asn Ala Lys Phe Val Leu Lys Ile Asn Asp Lys Ile

165 170 175Pro Tyr Ala Gln Ala Thr Phe Leu Arg Val Pro Lys Arg Ser Asp Pro

180 185 190Asn Ala His Thr Leu Asp Lys Gly Ala Ser Ile Asp Glu Ser Lys Leu

195 200 205Phe Glu Gln Gln Lys Lys Met Tyr Phe Asn Tyr Ala Asn Asp Val Ile

210 215 220Cys Arg Pro Asn Asp Glu Val Cys Ser Pro Leu Arg Asp Glu Met Val225 230 235 240Ala Met Pro Thr Asn Asp Ser Val Thr Gln Lys Pro Asn Ile Ile Ala

245 250 255Pro Tyr Ser Leu Tyr Arg Leu Lys Glu Thr Asn Asn Ala Asn Glu Ala

260 265 270Gln Pro Ser Pro Tyr Ala Thr Gln Thr Ala Pro Glu Asn Ser Lys Glu

275 280 285Lys Leu Ile Glu Glu Leu Ile Ala Asn Ser Gln Leu Ile Ala Asn Glu

290 295 300Glu Glu Arg Glu Lys Lys Leu Leu Ala Glu Lys Glu Lys Gln Glu Thr305 310 315 320Glu Leu Ala Lys Tyr Lys Leu Lys Asp Leu Glu Asn Gln Lys Lys Leu

325 330 335Lys Ala Leu Glu Ala Glu Leu Lys Lys Lys Asn Thr Lys Lys Pro Arg

340 345 350Val Val Glu Val Pro Ile Pro Pro Lys Thr Ser Asp Ser Asp Glu Thr

355 360 365Met Arg Val Ile Lys Glu Lys Glu Asn Tyr Asn Gly Leu Leu Val Asp

370375 380Lys Glu Thr Thr Ile Lys Arg Ser Tyr Lys Gly Thr Leu Ile Ser Glu385 390 395 400Asn Ser Tyr Ser Lys Lys Thr Pro Ile Asn Leu Glu Asp Leu Arg Ser

405 410 415Leu Glu Glu Glu Ile Lys Ser Tyr Tyr Val Lys Ser Asn Gly Leu Cys

420 425 430Tyr Ala Asn Gly Ile Asn Leu Tyr Val Lys Ile Lys Asn Asp Pro Tyr

435 440 445Lys Glu Gly Met Leu Cys Gly Tyr Glu Ser Val Gln Lys Leu Leu Ser

450 455 460Pro Leu Arg Asp Lys Leu Lys Tyr Asp Lys Gln Lys Leu Gln Lys Ala465 470 475 480Leu Leu Lys Asp Leu Lys

485(2) SEQ ID NO 543 message

Sequence properties:

(A) length: 101 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 101

(xi) sequence representation: SEQ ID NO 543: Val Val Gly Thr Met Glu Asp Phe Leu Tyr Asn Thr Leu Tyr Phe Ile 151015 Glu Asp Tyr Lys Leu Val Val Ile Phe Ser Phe Ile Gly Leu Ile Ala

20 25 30Leu Phe Phe Leu Tyr Lys Phe Ile Lys Thr Gln Lys Lys Val Phe Lys

35 40 45Asp Lys Ala Asn Gln Pro Gln Lys Lys Lys Ser Phe Lys Glu Ile Ile

50 55 60Ile Asp Gly Leu Lys Glu Arg Val Lys Thr Phe Gly Phe Trp Leu Pro6 5 70 75 80Ser Tyr Thr Ile Thr Ile Leu Phe Phe Tyr His Ile Arg Val Ile Phe

85 90 95Leu Asp Ser Leu Arg

100(2) SEQ ID NO 544 message

Sequence properties:

(A) length: 293 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 293

(xi) sequence representation: 544 SEQ ID NO: Arg Met Ala Gln Ile Val Lys Gly Ser Asp Met Phe Glu Asp Phe Tyr 151015 Arg Thr Thr Leu Ser Phe Leu Arg Ser Leu Leu Leu Leu Leu Gly Leu

20 25 30Leu Leu Pro Phe Ser Leu Cys Ile Ala Asp Glu Tyr Ile Ser Ile Ser

35 40 45Asp Asp Trp Asp Glu Arg Ala Arg Asn Gln Trp Asp Glu Thr Ala Arg

50 55 60Asn His Lys Thr Tyr Tyr Phe Glu Asn Gly Leu Asp His Phe Asn Gln65 70 75 80Gly Gln Tyr Lys Gln Ala Phe Lys Asp Phe LysLeu Ala Gln Glu Tyr

85 90 95Ser Ile Gly Leu Gly Asn Val Tyr Leu Ala Lys Met Tyr Leu Glu Gly

100 105 110Lys Gly Val Lys Val Asp Tyr Lys Lys Ala Gln Phe Tyr Ala Gln Asn

115 120 125Ala Ile Lys Gly Tyr Gly Ser Gly Leu Leu Gly Gly Ala Leu Ile Leu

130 135 140Gly Arg Met Gln Ala Glu Gly Leu Gly Met Lys Lys Asp Leu Lys Gln145 150 155 160Ala Leu Lys Thr Tyr Arg His Val Val Arg Met Phe Ser Asn Lys Ser

165 170 175Ala Asn Phe Ala Asn Lys Phe Gly Ser Asn Leu Ala Glu Phe Thr Ser

180 185 190Met Leu Ile Gly Ser Arg Phe Ile Asp Leu Ser Gly Leu Ser Ala Asn

195 200 205 Pro Ile Lys Phe Gly Asn Lys Phe Gly Ile Leu Val Lys Lys Ala Leu

210 215 220Gln Ile Lys Asp Asn Thr Leu Ser Trp Glu Asp Ile Ala Glu Ile Ser225 230 235 240Ser Asn Ile Ile Leu Leu Lys Gln Gln Met Gly Glu Ile Leu Tyr Arg

245 250 255Ile Gly Ile Ala Tyr Lys Glu Gly Leu Gly Thr Arg Lys Lys Lys Asp

260 265 270Arg Ala Lys Lys Phe Leu Gln Lys Ser Ala Glu Phe Gly Tyr Glu Lys

275 280 285Ala Met Glu Ala Leu

290(2) SEQ ID NO 545 information

Sequence properties:

(A) length: 81amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 81

(xi) sequence representation: SEQ ID NO 545: Asp Phe His Asp Phe Cys Ala Asn Ile His His Arg Ile Arg Trp Arg 151015 His Arg His Ile Ala Ser Leu Leu Ser Arg Ser Met Pro Lys Ile His

20 25 30Ala Val Phe Lys Ala Phe Ile Pro Ile Pro Phe Ala Leu Phe Ala Ile

35 40 45His Phe Val Val Leu Gly Ile Gly Ser Val Phe Asn Leu Asn Arg Ile

505560 Lys Asp Lys Lys Phe Ile Leu Arg Ala Lys Ile Ser His Ile Ala Gln 657075 Ala 80(2) information SEQ ID NO 546

Sequence properties:

(A) length: 104 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 104

(xi) sequence representation: 546: Lys Ala Met Leu Ser Ser Thr Asn Asp Ile Arg Tyr Gln Asn Pro Lys 151015 Asn Lys Ala Leu Lys Gly Glu Ile Leu Ala Asn Leu Lys Phe Ile Lys SEQ ID NO

20 25 30Lys Leu Leu Gly Ile Gly Cys Lys Asp Pro Ser Ala Tyr Val Gln Leu

35 40 45Gly Val Ser Lys Ser Glu Lys Gln Glu Ile Glu Asn Lys Ile Glu Glu

50 55 60Arg Lys Arg Ala Lys Glu Gln Lys Asp Phe Leu Lys Ala Asp Ser Ile65 70 75 80Arg Glu Glu Leu Leu Gln Gln Lys Ile Ala Leu Met Asp Thr Pro Gln

85 90 95Gly Thr Ile Trp Glu Lys Leu Phe

100(2) information of SEQ ID NO:547

Sequence properties:

(A) length: 529 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 529

(xi) sequence representation: SEQ ID NO 547: Met Arg Lys Val Ile Ile Met Asn Gly Tyr Leu Arg Val Lys Thr Pro 151015 Tyr Phe Leu Ala Ser Val Val Leu Thr Phe Trp Thr Phe Asn Ser Phe

20 25 30Met Ser Ala Lys Asp Lys His His Phe Leu Lys Lys Val Thr Thr Thr

35 40 45Glu Gln Lys Phe Ser Ser Ser Ala Pro Ile Ser Trp Gln Ser Glu Glu

50 55 60Val Arg Asn Ser Thr Ser Ser Arg Thr Val Ile Ser Asn Lys Glu Leu65 70 75 80Lys Lys Thr Gly Asn Leu Asn Ile Glu Asn Ala Leu Gln Asn Val Pro

85 90 95Gly Ile Gln Ile Arg Asp Ala Thr Gly Thr Gly Val Leu Pro Lys Ile

100 105 110Ser Val Arg Gly Phe Gly Gly Gly Gly Asn Gly His Ser Asn Thr Asn115 120 125Met Ile Leu Val Asn Gly Ile Pro Ile Tyr Gly Ala Pro Tyr Ser Asn

130 135 140Ile Glu Leu Ala Ile Phe Pro Val Thr Phe Gln Ser Val Asp Arg Ile145 150 155 160Asp Val Ile Lys Gly Gly Thr Ser Val Gln Tyr Gly Pro Asn Thr Phe

165 170 175Gly Gly Val Val Asn Val Ile Thr Lys Glu Ile Pro Lys Glu Trp Glu

180 185 190Asn Gln Ala Ala Glu Arg Ile Thr Phe Trp Gly Arg Ser Ser Asn Gly

195 200 205Asn Phe Val Asp Pro Lys Glu Lys Gly Lys Pro Leu Ala Gln Thr Leu

210 215 220Gly Asn Gln Met Leu Phe Asn Thr Tyr Gly Arg Thr Ala Gly Met Leu225 230 235 240Gly Lys Tyr Ile Gly Ile Ser Ala Gln Gly Asn Trp Ile Asn Gly Gln

245 250 255Gly Phe Arg Gln Asn Ser Pro Thr Lys Val Gln Asn Tyr Leu Leu Asp

260 265 270Ala Ile Tyr Lya Ile Asn Ala Thr Asn Thr Phe Lys Ala Tyr Tyr Gln

275 280 285Tyr Tyr Gln Tyr Asn Ser Tyr His Pro Gly Thr Leu Ser Ala Gln Asp

290 295 300Tyr Ala Tyr Asn Arg Phe Ile Asn Glu Arg Pro Asp Asn Gln Asp Gly305 310 315 320Gly Arg Ala Lys Arg Phe Gly Ile Val Tyr Gln Asn Tyr Phe Gly Asp

325 330 335Pro Asp Arg Lys Val Gly Gly Asp Phe Lys Phe Thr Tyr Phe Thr His

340 345 350Asp Met Ser Arg Asp Phe Gly Phe Ser Asn Gln Tyr Gln Ser Val Tyr

355 360 365Met Ser Gly Gln Asn Lys Ile Leu Pro Phe Lys Gly Lys Gly Glu Ile

370 375 380Ser Ala Lys Asn Pro Asn Cys Gly Leu Tyr Ser Tyr Ser Asp Thr Asn385 390 395 400Ser Pro Cys Trp Gln Phe Phe Asp Asn Ile Arg Arg Ser Val Val Asn

405 410 415Ala Phe Glu Pro Lys Leu Asn Leu Ile Val Asn Thr Gly Lys Val Lys

420 425 430Gln Thr Phe Asn Met Gly Met Arg Phe Leu Thr Glu Asp Leu Tyr Arg

435 440 445Arg Ser Thr Thr Arg Lys Asn Pro Ser Met Pro Asn Asn Gly Ser Gly

450 455 460Phe Asp Ala Gly Thr Ser Leu Asn Asn Phe Asn Asn Tyr Thr Ala Val465 470 475 480Tyr Ala Ser Asp Glu Ile Asn Phe Asn Asn Gly Met Leu Thr Ile Thr

485 490 495Pro Gly Leu Arg Tyr Thr Phe Leu Asn Tyr Glu Lys Lys Asp Ala Pro

500505 510 Pro Phe Lys Val Gly Gln Thr Pro Lys Thr Thr Lys Glu Arg Tyr Asn

515520525 Gln (2) SEQ ID NO:548 information

Sequence properties:

(A) length: 194 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 194

(xi) sequence representation: 548 SEQ ID NO: Arg Val Gly Phe Arg Ser Phe Ser Gly Gly His Cys Ala Glu Ile Phe

5 10 15Arg Phe Asn Pro His Pro Met Ala Phe Cys Ala Arg Gln Lys Pro Leu

20 25 30Lys Glu Ile Met Arg Phe Phe Ile Leu Phe Phe Met Gly Met Leu Gly

35 40 45Val Gly Phe Ser Gln Thr Glu Leu Asp Leu Lys Asp Leu Glu Lys Lys

50 55 60Pro Ala Gly Ile Val Arg Asp Tyr Tyr Leu Trp Arg Tyr Ile Ser Asp65 70 75 80Lys Lys Thr Ser Leu Glu Asn Ala Lys Lys Ala Tyr Glu Leu Thr Gln

85 90 95Asn Lys Asn Ser Ala Leu Gln Lys Ala Met Gln Glu Lys Gly Val Glu

100105 110Asn Ser Asp Lys Ser Pro Asp Ala Lys Met Pro Glu Asp Ile Tyr Cys

115 120 125Lys Gln Ile Thr Leu Glu Ser Met Leu Glu Thr Thr Asp Ala Phe Gln

130 135 140Ala Ser Cys Ile Ala Ile Ala Leu Lys Ser Lys Ile Arg Asp Phe Asp145 150 155 160Lys Ile Pro Ile Gln Thr Phe Lys Pro Leu Gln Glu Lys Ile Lys Glu

165 170 175Ala Tyr Pro Ile Leu Tyr Glu Glu Leu Glu Ile Leu Gln Ser Lys Asn

180185190 Val Ser (2) SEQ ID NO:549 information

Sequence properties:

(A) length: 206 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 206

The sequence expression: SEQ ID NO 549: His Ala Leu Tyr Ser Pro Ile Lys Ile Ala Phe Glu Lys Ala Leu Lys 151015 Asn Ala Lys Glu Ser Val Phe Ile Ala Ser Ser Tyr Phe Ile Pro Gly

20 25 30Lys Lys Ile Met Lys Ile Phe Lys Asn Gln Ile Ser Lys Gly Ile Glu

35 40 45Leu Asn Ile Leu Thr Asn Ser Leu Ser Ser Thr Asp Ala Ile Val Val

50 5560Tyr Gly Ala Trp Glu Arg Tyr Arg Asn Lys Leu Val Arg Met Gly Ala65 70 75 80Asn Val Tyr Glu Ile Arg Asn Asp Phe Phe Asn Arg Gln Ile Lys Gly

85 90 95Arg Phe Ser Thr Lys His Ser Leu His Gly Lys Thr Ile Val Phe Asp

100 105 110Asp Ala Leu Thr Leu Leu Gly Ser Phe Asn Ile Asp Pro Arg Ser Ala

115 120 125Tyr Ile Asn Thr Glu Ser Ala Val Leu Phe Asp Asn Pro Ser Phe Ala

130 135 140Lys Arg Val Arg Leu Ser Leu Lys Asp His Ala Gln Gln Ser Trp His145 150 155 160Leu Val Leu Tyr Arg His Arg Val Ile Trp Glu Ala Thr Glu Glu Gly

165 170 175Ile Leu Ile His Glu Lys Asn Ser Pro Asp Thr Ser Phe Phe Leu Arg

180 185 190Leu Ile Lys Glu Trp Ser Lys Val Leu Pro Glu Arg Glu Leu

195200205 (2) SEQ ID NO 550 information

Sequence properties:

(A) length: 442 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 442

(xi) sequence representation: 550: Gly Lys Ile Lys Gly Val Met Met Lys Phe Phe Leu Leu Lys Lys Phe 151015 Ser Glu Phe Leu Asn Thr Gln Thr His Phe Asn Leu Lys Arg Leu Asn SEQ ID NO

20 25 30Ala Ser Ser Phe Leu Leu Glu Thr Phe Ser Lys Glu Lys His Ala Phe

35 40 45Val Val Asp Leu Ser Ala Pro Tyr Ile Gly Leu Ser Lys Lys Pro Pro

50 55 60Glu Ser Val Leu Lys Asn Thr Leu Ala Leu Asp Phe Cys Leu Asn Lys65 70 75 80Phe Thr Lys Asn Ala Lys Ile Leu Gln Ala Asn Val Ile Asp Asn Asp

85 90 95Arg Ile Leu Glu Ile Lys Gly Ala Lys Asp Leu Ala Tyr Lys Ser Glu

100 105 110Thr Phe Ile Leu Arg Leu Glu Met Ile Pro Lys Lys Ala Asn Leu Met

115 120 125Ile Leu Asp Gln Glu Lys Cys Val Ile Glu Ala Phe Arg Phe Asn Asp

130 135 140Arg Val Ala Lys Asn Asp Ile Leu Gly Ala Leu Pro Pro Asn Ile Tyr145 150 155 160Glu His Gln Glu Glu Asp Leu Asp Phe Lys Gly Leu Leu Asp Ile Leu

165 170 175Glu Lys Asp Phe Leu Ser Tyr Gln His Lys Glu Leu Glu His Lys Lys

180 185 190Asn Gln Ile Ile Lys Arg Leu Asn Ala Gln Lys Glu Arg Leu Lys Glu

195 200 205Lys Leu Glu Lys Leu Glu Asp Pro Lys Thr Leu Gln Leu Glu Ala Lys

210 215 220Glu Leu Gln Thr Gln Ala Ser Leu Leu Leu Thr Tyr Gln His Leu Ile225230 235 240Asn Arg Arg Glu Asn Arg Val Ile Leu Lys Asp Phe Glu Asp Lys Glu

245 250 255Cys Met Ile Glu Ile Asp Lys Ser Met Pro Leu Asn Ala Phe Ile Asn

260 265 270Lys Lys Phe Thr Leu Ser Lys Lys Lys Lys Gln Lys Ser Gln Phe Leu

275 280 285Tyr Leu Glu Glu Glu Asn Leu Lys Glu Lys Ile Ala Phe Lys Glu Asn

290 295 300Gln Ile Asn Tyr Val Arg Asp Ala Ala Glu Glu Ser Val Leu Glu Met305 310 315 320Phe Met Pro Val Lys Asn Ser Lys Ile Lys Arg Pro Met Asn Gly Tyr

325 330 335Glu Val Leu Tyr Tyr Lys Asp Phe Lys Ile Gly Leu Gly Lys Asn Gln

340 345 350Lys Glu Asn Ile Lys Leu Leu Gln Asp Ala Arg Ala Asn Asp Leu Trp

355 360 365Met His Val Arg Asp Ile Pro Gly Ser His Leu Ile Val Phe Cys Gln

370 375 380Lys Asn Thr Pro Lys Asp Glu Val Ile Met Glu Leu Ala Lys Met Leu385 390 395 400Ile Lys Met Gln Lys Asp Ala Phe Asn Gly Tyr Glu Ile Asp Tyr Thr

405 410 415Gln Arg Lys Phe Val Lys Ile Ile Lys Gly Ala His Val Ile Tyr Ser

420 425 430Lys Tyr Arg Thr Ile Ser Leu Lys Asp Thr

435440 (2) SEQ ID NO 551 information

Sequence properties:

(A) length: 293 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 293

(xi) sequence representation: 551: Gly Phe Met Met Ile Phe Ile Asp Ala Cys Phe Arg Lys Glu Thr Pro 151015 Tyr Thr Pro Ile Trp Met Met Arg Gln Ala Gly Arg Tyr Leu Ser Glu SEQ ID NO

20 25 30Tyr Gln Glu Ser Arg Lys Lys Ala Gly Ser Leu Leu Glu Leu Cys Lys

35 40 45Asn Ser Asp Leu Ala Thr Glu Val Thr Leu Gln Pro Val Glu Ile Leu

50 55 60Gly Val Asp Ala Ala Ile Leu Phe Ser Asp Ile Leu Val Val Pro Leu65 70 75 80Glu Met Gly Leu Asn Leu Glu Phe Ile Pro Lys Lys Gly Pro His Phe

85 90 95Leu Glu Thr Ile Thr Asp Leu Lys Ser Val Glu Ser Leu Lys Val Gly

100 105 110Val Tyr Lys Gln Leu Asn Tyr Val Tyr Asp Thr Ile Ser Gln Thr Arg

115 120 125 Gln Lys Leu Ser Lys Glu Lys Ala Leu Ile Gly Phe Cys Gly Ser Pro

130 135 140Trp Thr Leu Ala Thr Tyr Met Ile Glu Gly Glu Gly Ser Lys Ser Tyr145 150 155 160Ala Lys Ser Lys Lys Met Leu Tyr Ser Glu Pro Glu ValLeu Lys Ala

165 170 175Leu Leu Glu Lys Leu Ser Leu Glu Leu Ile Glu Tyr Leu Ser Leu Gln

180 185 190Ile Gln Ala Gly Val Asn Ala Val Met Ile Phe Asp Ser Trp Ala Ser

195 200 205Ala Leu Glu Lys Glu Ala Tyr Leu Glu Phe Ser Trp Asp Tyr Leu Lys

210 215 220Lys Ile Ser Lys Glu Leu Lys Lys Arg Tyr Ala His Ile Pro Val Ile225 230 235 240Leu Phe Pro Lys Gly Ile Gly Ala Tyr Leu Asp Ser Ile Asp Gly Glu

245 250 255Phe Asp Leu Phe Gly Leu Asp Gly Gly Thr Pro Leu Thr Ala Ala Lys

260 265 270Lys Lys Leu Ala Val Ile Ile Phe Leu Gln Gly Ile Tyr Asn Pro Pro

275 280 285Ala Phe Met Ile Lys

290(2) SEQ ID NO 552 information

Sequence properties:

(A) length: 192 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 192

(xi) sequence representation: 552: Arg Val Phe Leu Thr Lys Lys Phe Met Ser Trp Met Val Val Ile Gly 151015 Ala Leu Ile Cys Val Leu Leu Gly Val Phe Ile Phe Phe Thr Ser Met SEQ ID NO

20 25 30Ser Val Lys Lys Ser Leu Thr Ala Tyr Leu Asn Ala Tyr Leu Glu Gln

35 40 45Arg Pro Asn Ile Glu Gly Met Gly Ile Ile Gly Val Pro Phe Lys Cys

50 55 60Glu Arg Phe Phe Lys Ile Ala Cys Val Ser Lys Glu Leu Arg Phe Leu65 70 75 80Asn Pro Gln Asn Ser Pro Ile Met Asp Phe Lys Asn Leu Glu Ile Lys

85 90 95Leu His Ser Leu Asp Lys Ser Ser Leu Thr Leu Ser Ile His Ser Gln

100 105 110Ile Gln Ser Pro Ile Leu Glu Gln Ser Ile Gln Gln Lys Ile Ser Gln

115 120 125Ile Pro Leu Lys Asn Leu Asn Ala Leu Leu Glu Lys Phe Lys Pro Thr

130 135 140Arg Leu Asn Cys Ser Leu Thr Phe Asn Ala Leu Asp Glu Lys Thr Leu145 150 155 160Asn Asp Asn Leu Lys Cys Asp Leu Thr Asn Ala Glu Asn Leu Leu Leu

165 170 175His Phe Phe Ser Arg Gly Phe Asn Gly Gly Ala Arg Lys Ser Leu Pro

180185190 (2) SEQ ID NO 553 message

Sequence properties:

(A) length: 370 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 370

(xi) sequence representation: 553 SEQ ID NO:553: Gln Asp Gln Pro Met Gln Phe Gln Lys Thr Leu Leu Ser Leu Ser Leu 151015 Leu Phe Leu Ser Tyr Cys Ile Ala Glu Glu Asn Gly Ala Tyr Ala Ser

20 25 30Val Gly Phe Glu Tyr Ser Ile Ser His Ala Val Glu His Asn Asn Pro

35 40 45Phe Leu Asn Gln Glu Arg Ile Gln Thr Ile Ser Asn Ala Gln Asn Lys

50 55 60Ile Tyr Lys Leu Asn Gln Val Lys Asn Glu Ile Thr Asn Met Pro Asn65 70 75 80Thr Phe Asn Tyr Ile Asn Asn Ala Leu Lys Asn Asn Ala Lys Leu Thr

85 90 95Pro Thr Glu Lys Gln Ala Glu Thr Tyr Tyr Leu Gln Ser Thr Leu Gln

100 105 110Asn Ile Glu Lys Ile Val Met Leu Ser Gly Gly Val Ala Ser Asn Pro

115 120 125Lys Leu Ala Gln Ala Leu Glu Lys Met Gln Glu Pro Ile Thr Asn Pro

130 135 140Leu Glu Leu Val Glu Asn Leu Lys Asn Leu Glu Leu Gln Phe Ser Gln145 150 155 160Ser Gln Asn Ser Met Leu Ser Ser Leu Ser Ser Gln Ile Ala Gln Ile

165 170 175Ser Asn Ser Leu Asn Ala Leu Asp Pro Ser Ser Tyr Ser Lys Asn Val

180 185 190Ser Ser Met Tyr Gly Val Gly Leu Ser Val Gly Tyr Lys His PhePhe

195 200 205Thr Lys Lys Lys Asn Gln Gly Phe Arg Tyr Tyr Leu Phe Tyr Asp Tyr

210 215 220Gly Tyr Thr Asn Phe Gly Phe Val Gly Asn Gly Phe Asp Gly Leu Gly225 230 235 240Lys Met Asn Asn His Leu Tyr Gly Leu Gly Ile Asp Tyr Leu Phe Asn

245 250 255Phe Ile Asp Asn Ala Gln Lys His Ser Ser Val Gly Phe Tyr Val Gly

260 265 270Phe Ala Leu Ala Gly Ser Ser Trp Val Gly Ser Gly Leu Gly Met Trp

275 280 285Val Ser Gln Met Asp Phe Ile Asn Asn Tyr Leu Thr Asp Tyr Arg Ala

290 295 300Lys Met His Thr Ser Phe Phe Gln Ile Pro Leu Asn Phe Gly Val Arg305 310 315 320Val Asn Val Asp Arg His Asn Gly Phe Glu Met Gly Leu Lys Ile Pro

325 330 335Leu Ala Val Asn Ser Phe Tyr Glu Thr His Gly Lys Gly Leu Asn Ala

340 345 350Ser Leu Phe Phe Lys Arg Leu Val Met Phe Asn Val Ser Tyr Val Tyr

355 360 365Ser Phe

370(2) SEQ ID NO 554 information

Sequence properties:

(A) length: 243 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 243

(xi) sequence representation: SEQ ID NO 554: Glu Pro Met Pro Met Gly Lys Ala Leu Lys Glu Tyr Gln Ile Lys Lys 151015 Thr Arg Asp Val Gly Ile Gly Ala Lys Asn Ser Glu Ile Met Thr Ser

20 25 30Ala Gln Val Glu Leu Gly Lys Met Leu Tyr Phe Asp Pro Arg Ile Ser

35 40 45Thr Ser Tyr Leu Val Ser Cys Asn Thr Cys His Asn Leu Gly Leu Gly

50 55 60Gly Val Asp Leu Ile Pro Ser Ala Ile Gly Ser Gln Trp Lys Lys Asn65 70 75 80Pro His Leu Leu Ser Ser Pro Thr Val Tyr Asn Ser Val Phe Asn Asp

85 90 95Val Gln Phe Trp Asp Gly Arg Val Thr His Leu Asn Glu Gln Ala Gln

100 105 110Gly Pro Ile Gln Ser Ser Phe Glu Met Gly Ala Asp Pro Lys Val Val

115 120 125Val Glu Lys Ile Asn Ser Ile Pro Gly Tyr Val Lys Leu Phe Arg Lys

130 135 140Ala Tyr Gly Ser Lys Val Lys Ile Asp Phe Lys Leu Ile Ala Asp Ser145 150 155 160Ile Ala Met Phe Glu Ala Thr Leu Ile Thr Pro Ser Arg Tyr Asp Asp

165 170 175Phe Leu Arg Gly Asn Pro Lys Ala Leu Ser Lys Ala Glu Lys Glu Gly

180 185 190Leu Asp Leu Phe Ile Ser LysGly Cys Val Ala Cys His Asn Gly Ile

195 200 205Asn Leu Gly Gly Thr Met Gln Pro Phe Gly Val Val Lys Pro Tyr Lys

210215220 Phe Ala Asn Val Gly Asp Phe Lys Gly Asp Lys Asn Gly Leu Val Lys 225230235240 Val-Pro-Thr (2) SEQ ID NO:555 information

Sequence properties:

(A) length: 234 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 234

(xi) sequence representation: SEQ ID NO 555: Asn Asp Phe Trp Arg Lys Glu Ile Thr Met Arg Ala Thr Ala Ile Lys 151015 Ile Phe Ser Phe Ser Ser Ala Leu Ala Leu Leu Leu Gln Gly Cys Leu

20 25 30Ser Ile Asn Leu Lys Gln Met Leu Pro Glu Ile Arg Thr Tyr Asp Leu

35 40 45Asn Ala Ser Ser Phe Glu Met Thr Gln Cys Pro Lys Pro Leu Thr Glu

50 55 60Val Arg Leu Ile Ile Ile Leu Ser Ala Asp Leu Phe Asn Thr Lys Glu65 70 75 80Ile Val Phe Lys Ala Gln Asp Gly Gln Ile Thr His Gly Lys His Gln

85 90 95Lys Trp Ile Asp Leu Pro Arg Asn Met Leu Lys Thr Met Phe Met Gln

100 105 110Glu Ala Gln Lys Ala Cys Leu Gly Val Ala Leu Pro Pro Tyr Gly Ala

115 120 125Gly Ala Pro Thr Tyr Ala Val Arg Phe Thr Ile Leu Ser Phe Ser Leu

130 135 140Leu Glu Lys Glu Asn Ser Thr Tyr Arg Ala Glu Phe Ala Leu Gly Tyr145 150 155 160Asp Ile Ser Val Lys Gly Asp Ser His Ser Gly Val Ile Ile Lys His

165 170 175Glu Asn Ile Ser Ser Leu Glu Asn Lys Thr Thr Lys Thr Ser Lys Asn

180 185 190Gly Ser Gln Asp Phe Gln Glu Ser Ala Ile Gln Ser Leu Gln His Val

195 200 205Ser Thr Gln Ala Met Gln Glu Ala Ile Ser Leu Ile Lys Lys Ala Val

210215220 Glu Ala Gln Ser Val Ser Pro Leu Lys Lys 225230 (2) SEQ ID NO:556 information

Sequence properties:

(A) length: 283 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 283

(xi) sequence representation: 556: Arg Gln Phe Ile Gln Phe Asn Thr Arg Arg Glu Ile Leu Glu Arg His 151015 Val Asn Tyr Thr Leu Ile Gly Gly Leu Phe Phe Leu Cys Leu Val Cys SEQ ID NO

20 2530Met Val Gly Phe Ile Leu Trp Leu Gly His Leu Gly Leu Asp Asp Gly

35 40 45Lys Tyr Tyr Glu Tyr Val Val Tyr Thr Asp Lys Asp Leu Gly Gly Ile

50 55 60Ala Thr Asn Ser Pre Ile Asn Tyr Lys Gly Ile Gln Val Gly Asn Val65 70 75 80Ile Lys Val Gly Phe Ala Lys Asp Lys Val Gly Val Val Arg Leu Asp

85 90 95Leu Met Ile Lys Ser Ser Val Lys Ile Arg Lys Asp Ser Lys Val Ala

100 105 110Val Ser Ser Arg Gly Phe Met Gly Leu Lys Phe Leu Ala Leu Glu Gln

115 120 125Ser His Asn Glu Glu Phe Tyr Gly Ser Gly Asp Lys Gly Glu Arg Ile

130 135 140Leu Ile Phe Lys Glu Gly Leu Met Asp Arg Leu Ser Gly Asp Ala Asn145 150 155 160Gln Val Val Gln Glu Val Met Lys Ala Ile Arg Asn Val Asn Arg Ile

165 170 175Leu Asp Asp Glu Asn Val Glu Lys Phe Lys His Ile Leu Ala Ser Val

180 185 190Asp Asp Leu Ile Ala Asn Leu Asp Ser Arg Lys Thr Gln Phe Asp Ser

195 200 205Leu Ile Asn Asn Ala Asn Asn Leu Val Ser Asn Val Asn Asn Val Ala

210 215 220Leu Asp Val Asp Lys Arg Val Lys Gln Gly Gln Tyr Asp Phe Lys Ala225 230 235 240Met Phe Thr Pro Leu Ile Met Gln Ala Gln Leu Ser Leu Arg Asn Ile

245 250 255Asp Asn PheVal Glu Lys Gly Ser Ala Leu Ile Aso Lys Phe Asp Ala

260 265 270Asn Pro Tyr Lys Thr Ile Phe Gly Glu Arg Lys

275280 (2) SEQ ID NO 557 information

Sequence properties:

(A) length: 150 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 150

(xi) sequence representation: SEQ ID NO:557: Ser Ser Ser Gln Ser Ile Ala Leu Leu Ile Gly Leu Trp Phe Gly Phe 151015 Gln Lys Arg Ile Ala Leu Gly Val Trp Phe Phe Phe Ser Ile Leu Leu

20 25 30Gly Glu Phe Thr Leu Lys Ser Leu Lys Leu Leu Val Ala Arg Pro Arg

35 40 45Pro Val Thr Asn Gly Glu Leu Val Phe Ala His Gly Phe Ser Phe Pro

50 55 60Ser Gly His Ala Leu Ala Ser Ala Leu Phe Tyr Gly Ser Leu Ala Leu65 70 75 80Leu Leu Cys Tyr Ser Asn Ala Asn Asn Arg Ile Lys Thr Ile Gly Ala

85 90 95Ile Ile Leu Leu Phe Trp Ile Phe Leu Met Ala Tyr Asp Arg Val Tyr

100 105 110Leu Gly Val His Tyr Pro Ser Asp Val Leu Gly Gly Phe Leu Leu Gly

115 120 125Ile Ala Trp Ser Cys Cys Ser Leu Ala Leu Tyr Leu Gly Phe Leu Lys

130135140 Arg Pro Tyr Lys Ala Ala 145150 (2) SEQ ID NO:558 information

Sequence properties:

(A) length: 73 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 73

(xi) sequence representation: 558: Met Met Asp Leu Glu Ser Leu Arg Gly Phe Ala Tyr Ala Phe Phe Thr 151015 Ile Leu Phe Thr Leu Phe Leu Tyr Ala Tyr Ile Phe Ser Met Tyr Arg SEQ ID NO

20 25 30Lys Gln Lys Lys Gly Ile Val Asp Tyr Glu Arg Tyr Gly Tyr Leu Ala

35 40 45Leu Asn Asp Ala Leu Glu Asp Glu Leu Ile Glu Pro Arg His Lys Glu

505560 Val His Asp Lys Gly Ile Lys Glu Ser 6570 (2) SEQ ID NO:559 information

Sequence properties:

(A) length: 100 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 100

(xi) sequence representation: SEQ ID NO 559: Gly Asn Leu Met Gly Gln Thr Lys Glu Ile Ile Thr Thr Leu Leu Pro 151015 Leu Leu Val Leu Phe Leu Ile Phe Tyr Phe Leu Ile Val Arg Pro Gln

20 25 30Arg Gln Gln Gln Lys Lys His Lys Glu Met Ile Glu Gly Leu Thr Lys

35 40 45Gly Asp Lys Ile Val Thr Gln Gly Gly Leu Ile Val Glu Val Leu Lys

50 55 60Ala Glu Ala Asn Phe Phe Ser Val Lys Leu Asn Asp Asp Thr Thr Ala65 70 75 80Lys Leu Ser Lys Asn Tyr Val Ala Phe Lys Leu Asp Glu Glu Thr Thr

85 90 95Pro Asn Asn Asn

100(2) SEQ ID NO 560 information

Sequence properties:

(A) length: 159 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 159

(xi) sequence representation: 560: Met Lys Leu Phe Asn Pro Arg Leu Ile Val Phe Ile Phe Ala Leu Leu 151015 Leu Gly Val Gly Phe Ser Val Pro Ser Leu Leu GluThr Lys Gly Pro SEQ ID NO

20 25 30Lys Ile Thr Leu Gly Leu Asp Leu Arg Gly Gly Leu Asn Met Leu Leu

35 40 45Gly Val Gln Thr Asp Glu Ala Leu Lys Asn Lys Tyr Leu Ser Leu Ala

50 55 60Ser Ala Leu Glu Tyr Asn Ala Lys Lys Gln Asn Ile Leu Leu Lys Asp65 70 75 80Ile Lys Ser Ser Leu Glu Gly Ile Ser Phe Glu Leu Leu Asp Glu Asp

85 90 95Glu Ala Lys Lys Leu Asp Ala Leu Leu Leu Glu Leu Gln Gly His Ser

100 105 110Gln Phe Glu Ile Lys Lys Glu Ala Glu Phe Tyr Ser Val Lys Leu Thr

115 120 125Pro Leu Glu Gln Glu Glu Leu Arg Lys Asn Thr Ile Leu Gln Val Ile

130135140 Gly Ile Ile Arg Ile Arg Leu Asp His Leu Ala Trp Gln Ser Leu 145150155 (2) SEQ ID NO:561 information

Sequence properties:

(A) length: 88 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 88

The sequence expression: SEQ ID NO 561: Gly Asn Val Lys Val Asn Lys Lys His Arg Leu Ala Phe Leu Gly Leu 151015 Ile Val GlyVal Leu Phe Phe Phe Ser Ala Cys Gln His Arg Leu His

20 25 30Met Gly Tyr Tyr Ser Glu Val Thr Gly Asp Tyr Leu Phe Asn Tyr Asn

35 40 45Ser Thr Ile Val Val Ala Tyr Asp Arg Ser Asp Ala Met Thr Ser Tyr

50 55 60Tyr Ile Asn Val Ile Val Tyr Glu Leu Gln Lys Leu Gly Phe Tyr Asn65 70 75 80Val Phe Thr Gln Ala Asn Ser Arg

85(2) SEQ ID NO 562 message

Sequence properties:

(A) length: 165 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 165

(xi) sequence representation: 562: Lys Ala Leu Met Val Gly Met Lys Thr Gly Ala Trp Thr Gly Leu Lys 151015 Leu Phe Ala Gln Pro Leu Leu Val Val Leu Ala Phe Met Leu Leu Tyr SEQ ID NO

20 25 30Ala Leu Ala His Ala Val Leu Gly Phe Tyr Val Lys Lys Asp Ser Ala

35 40 45Pro Met Ser Pro Asn Val Glu Lys Ser Glu Thr Glu Arg Gln Asn Ser

50 55 60Thr Phe Ser Pro Lys Glu Glu Ala Asn Ala Thr Thr Thr Ala Thr Glu65 7075 80Gln Asn Pro Thr Lys Asp Thr Val Pro Pro Leu Asp Thr Ala Thr Gln

85 90 95Lys Gln Glu Ile Lys Gln Glu Ile Lys Gln Glu Ile Lys Gln Glu Ile

100 105 110Lys Gln Glu Ile Lys Gln Glu lle Lys Gln Glu Ile Lys Gln Glu Thr

115 120 125Lys Gln Glu Gln Glu Lys Glu Asn Lys Pro Lys Gln Asn Ser Val Ser

130 135 140Pro Val Gln Asn Asp Gln Lys Thr Pro Thr Thr Pro Leu Met Gly Lys145 150 155 160Lys Thr Ser Arg Val

165(2) SEQ ID NO:563 information

Sequence properties:

(A) length: 97 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 97

(xi) sequence representation: SEQ ID NO:563: Met Leu Tyr Ala Ser Lys Ala Arg Leu Phe Leu Gln Ile Lys Gly Lys 151015 Phe Met Leu Arg Ile Leu Ile Pro Leu Leu Ile Ile Val Trp Val Leu

20 25 30Trp Arg Leu Phe Leu Arg Gln Lys Pro His Lys Asp Asp His Arg Asp

35 40 45Asn His Ser Tyr Thr Gln Gln Thr Pro Lys Glu Leu Glu AspHis Met

50 55 60Ile Val Cys Ser Lys Cys Gln Thr Tyr Val Ser Ser Lys Asp Ala Ile65 70 75 80Tyr Ser Gly Ala Val Ala Tyr Cys Ser Glu Thr Cys Leu Lys Asp Lys

859095 Gly (2) SEQ ID NO 564 information

Sequence properties:

(A) length: 84 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 84

(xi) sequence representation: 564: Lys Thr Ile Asn Lys Leu Arg Ile Ile Met Lys Pro Thr Asn Glu Pro 151015 Lys Lys Pro Phe Phe Gln Ser Pro Ile Val Leu Ala Val Leu Gly Gly SEQ ID NO

20 25 30Ile Leu Leu Ile Phe Phe Leu Arg Ser Phe Asn Ser Asp Gly Ser Phe

35 40 45Ser Asp Asn Phe Leu Ala Ser Ser Thr Lys Asn Val Ser Tyr His Glu

505560 Ile Lys Gln Leu Ile Ser Asn Asn Glu Val Glu Asn Val Ser Ile Gly 65707580 Gln Thr Leu Ile (2) SEQ ID NO:565 information

Sequence properties:

(A) length: 230 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 230

(xi) sequence representation: SEQ ID NO 565: Phe Lys Asn Asn Lys Thr Pro Leu Thr Phe Glu Arg Asp Lys Gly Ser 151015 Leu Asp Gly Leu Lys Lys Glu Arg Gln Gly Phe Tyr Lys Gln Val His

20 25 30Tyr Leu Arg Ile Leu Ile Leu Ser Met Ser Phe Leu Asn Ile Leu Asn

35 40 45Ala Glu Asn Leu Ser Tyr Met Ser Ser Ser Tyr Gln Ile Gly Thr Val

50 55 60Phe Met Arg Pro Leu Asn Thr Asn Lys Leu Leu Gln Gly Ala Ser Ile65 70 75 80Leu Gln Gly Tyr Glu Val Asn Pro Lys Asn Asp Trp Ala Tyr Ser Arg

85 90 95Tyr Tyr Phe Phe Ile Asp Tyr Gly Asn Val Leu Phe Asn Asn Asp Ser

100 105 110Thr Leu Gln Ala Asn Met Phe Thr Tyr Gly Val Gly Gly Asp Phe Met

115 120 125Val Ala Tyr Ala Lys Asn Pro Ile Asn Arg Trp Ala Phe Phe Phe Gly

130 135 140Leu Gln Leu Ala Ala Asn Thr Trp Ile Leu Asn Asn Lys Val Lys Asp145 150 155 160Leu Val Val Asn Thr Trp Asp Ser Leu Lys Asp Phe Asn Phe His Asn

165 170 175Thr Tyr Phe Arg Ala Ile Gly Lys Phe Gly Val Gln Phe Arg Thr Ile

180 185 190Val Leu Tyr His Lys Val Asp Val Glu Ile Gly Met Lys Ile Phe Leu

195 200 205Thr Pro Glu Arg Arg Ser Leu Phe Glu Arg Ser Phe Leu Phe Phe Val

210215220 Ser His Ser Trp His Phe 225230 (2) SEQ ID NO:566 messages

Sequence properties:

(A) length: 209 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 209

(xi) sequence representation: SEQ ID NO 566: Gly Ile Cys Leu Lys Phe Gln Ile Val Ser Leu Leu Leu Ala Phe Leu 151015 Leu Ala Ser Cys Leu Pro Pro Lys Gly His His Ser Gly Leu Val Asn

20 25 30Met Tyr Ile Ala His Gln Gly Gln Ser Val Arg Thr Tyr Trp Arg Lys

35 40 45Val Asp Arg Gly Val Val Ala Lys His Asn Glu Thr Leu Lys Glu Asn

50 55 60Pro Lys Ile Lys Leu Lys Asp Pro Lys Gly Pro Leu Phe Met Leu Gly65 70 75 80Ser Asn Arg Phe Met Leu Leu Trp Lys Asn Arg Tyr Thr Leu Ala Lys

85 90 95Val Gln Ser Phe Lys Leu Glu Pro Gly Phe Tyr Tyr Leu Asp Ser Phe

100 105 110Ser Val Glu Thr Gln Lys Gly Ile Leu Gln Ser Ala Pro Gly Tyr Ser

115 120 125Tyr Thr Lys Asn Gly Tyr Asp Phe Lys Asn Asn Arg Pro Phe Phe Leu

130 135 140Ala Phe Glu Val Lys Pro Asp Ser Lys Ile Val Leu Pro Ser Val Glu145 150 155 160Leu Ser Leu Ile Lys Thr Pro Arg Gly Phe Leu Gly Val Phe Leu Phe

165 170 175Asp Asn Asn Glu Lys Gly Ala Asn Thr Pro Trp Ile Glu Gly Ser Leu

180 185 190Asn Leu Lys Leu Lys Asn Ala Ser Phe Lys Asp Ala Trp Glu Leu Glu

195200205 Arg (2) SEQ ID NO:567 message

Sequence properties:

(A) length: 170 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 170

The sequence expression: 567: Lys Pro Phe Gly Tyr Leu Gly Leu Leu Tyr Lys Gln Gly Thr Gln Lys 151015 Asn Pro His Ser Tyr Val Gly Ala Pro Ala Arg Leu Gly Val Asp Phe SEQ ID NO

20 25 30Ser Tyr Ser Asn Gly Trp Ser Phe Gly Ile Gly Ala Ile Gly Ala Trp

35 40 45Asn Ile Tyr Asn Lys Gln Arg Leu Ala Asn Leu Tyr Ile Ser Leu Gly

50 55 60Asn Phe Phe Gly Asn Pro Asn Asn Val Lys Pro Tyr Leu Ser Ala Gly65 70 75 80Asp Val Ser Asp Ala Tyr Leu Gln Tyr Ala Asn Gln Arg Phe Lys Ile

85 90 95Ala Leu Gly Arg Phe Asn Thr Asp Phe Va1 Asp Phe Asp Trp Ile Gly

100 105 110Gly Asn Ile Gln Gly Val Ser Val Ala Phe Lys Gln Asn Ser Met Arg

115 120 125Tyr Phe Gly Ile Phe Met Asp Ser Met Leu Tyr Asn Gly His Gln Ile

i30 135 140Asn Lys Glu Gln Gly Asn Arg Ile Ala Thr Phe Leu Asn Ala Leu Ala145 150 155 160Leu Met Ile Leu Cys Leu Asn Ala Cys Met

165170 (2) SEQ ID NO 568 INFORMATION

Sequence properties:

(A) length: 195 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 195

(xi) sequence representation: 568: Leu Gly Ser Pro Met Gln Phe Gln Lys Thr Leu Ser Ser Leu Ser Leu 151015 Phe Leu Ser Leu Ser Leu Phe Leu Ser Phe Ser Ile Ala Glu Glu Asn SEQ ID NO

20 25 30Gly Ala Tyr Ala Ser Val Gly Phe Glu Tyr Ser Ile Ser His Ala Val

35 40 45Glu His Asn Asn Pro Phe Leu Asn Gln Glu Arg Ile Gln Thr Ile Ser

50 55 60Asn Ala Gln Asn Gln Ile Tyr Lys Leu Asn Gln Ile Glu Asn Glu Ile65 70 75 80Thr Asn Met Gln Asn Thr Phe Asn Tyr Thr Asn Asn Ala Leu Lys Asn

85 90 95Asn Ala Lys Leu Thr Pro Thr Glu Met Gln Ala Glu Gln Tyr Tyr Leu

100 105 110Gln Ser Thr Leu Gln Asn Ile Glu Lys Ile Val Met Leu Ser Gly Gly

115 120 125Val Ala Ser Asn Pro Lys Leu Val Gln Ala Leu Glu Lys Met Gln Glu

130 135 140Pro Ile Thr Asn Pro Leu Glu Leu Val Glu Asn Leu Lys Asn Leu Glu145 150 155 160Leu Gln Phe Ser Gln Ser Gln Asn Ser Met Leu Ser Ser Leu Ser Ser

165 170 175Gln Ile Ala Gln Ile Ser Asn Ser Leu Asn Ala Leu Asp Pro Ser Ser

180 185 190Tyr Ser Lys

195(2) SEQ ID NO:569 message

Sequence properties:

(A) length: 72 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 72

(xi) sequence representation: SEQ ID NO:569: Lys Gly Lys Val Met Asn Ser Ser Asn Leu Lys Asn Trp Leu Phe Pro 151015 Thr Ile Cys Phe Phe Leu Phe Cys Tyr Ile Leu Ile Phe Leu Ile Phe

20 25 30Phe Met Phe Lys Asn Leu Gln Ser Gln Ser Phe Gly Ser Val Ala Glu

35 40 45Thr Gly Lys Lys Pro Ile Thr Thr Thr Lys Lys Phe Gly Lys Glu Leu

505560 Gln Lys Gln Ile Ser Lys Ile His 6570 (2) SEQ ID NO:570 information

Sequence properties:

(A) length: 278 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 278

(xi) sequence representation: 570: Leu Met Arg Lys Val Leu Tyr Ala Leu Met Gly Phe Leu Leu Val Phe 151015 Ser Ala Leu Lys Ala Asp Asp Phe Leu Glu Glu Ala Asn Glu Thr Ala SEQ ID NO

20 25 30Pro Ala Asn Leu Asn His Pro Met Gln Asp Leu Asn Ala Ile Gln Gly

35 40 45Ser Phe Phe Asp Lys Asn Arg Ser Lys Met Ser Asn Thr Leu Asn Ile

50 55 60Asp Tyr Phe Gln Gly Gln Thr Tyr Lys Ile Arg Leu Arg Tyr Ala Met65 70 75 80Ala Thr Leu Leu Phe Phe Ser Lys Pro Ile Ser Asp Phe Val Leu Gly

85 90 95Asp Lys Val Gly Phe Asp Ala Lys Ile Leu Glu Ser Asn Asp Arg Ile100 105 110Leu Leu Ile Lys Pro Leu Gln Ile Gly Val Asp Ser Asn Ile Ser Val

115 120 125Ile Asp Ser Glu Gly Lys Ile Phe Ser Phe Tyr Val Phe Ser Thr Thr

130 135 140Phe Thr Ser Ser Lys His Pro Asn Leu Gln Val Phe Ile Glu Asp Lys145 150 155 160Asn Tyr Tyr Thr Asn Ala Phe Ile Lys Pro Gln Lys Glu Asn Gln Glu

165 170 175Asn Met Ser Glu Asn Ala Pro Lys Asp Ala Gln Lys Asn Asn Lys Pro

180 185 190Leu Lys Glu Glu Lys Glu Glu Thr Lys Glu Lys Glu Glu Glu Thr Ile

195 200 205Ile Ile Gly Asp Asn Thr Asn Ala Met Lys Ile Ile Lys Lys Asp Ile

210 215 220Gln Lys Gly Tyr Lys Ala Leu Lys Ser Ser Gln Arg Lys Trp Tyr Cys225 230 235 240Leu Trp Ala Cys Ser Lys Lys Ser Lys Leu Ser Leu Met Pro Lys Glu

245 250 255Ile Phe Asn Asp Lys Gln Phe Thr Tyr Phe Lys Phe Asp Lys Arg Leu

260 265 270Ala Leu Ser Lys Ser Arg

275(2) SEQ ID NO 571 information

Sequence properties:

(A) length: 60 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 60

(xi) sequence representation: 571: Tyr Arg Glu Met Asp Tyr Ala Val Phe Ser Met Thr Ile His Pro Asp 151015 Val Ser Ala Arg Pro Gln Val Leu Leu Met His Glu Lys Ile Ile Glu SEQ ID NO

20 25 30His Ile Asn Gln His Glu Gly Val Ala Trp Val Thr Phe Asn Glu Ile

35 40 45Ala Asp Asp Phe Leu Lys Arg Asn Pro Arg Lys Lys

505560 (2) SEQ ID NO:572 information

Sequence properties:

(A) length: 78 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 78

(xi) sequence representation: 572: Leu Val Leu Gln Gly Ala Glu Val LeuIle Tyr Pro Ser Ala Phe Gly 151015 Lys Ala Arg Ala Tyr Asn Trp Asp Leu Leu Ser Lys Ala Arg Ala Leu SEQ ID NO

20 25 30Glu Asn Gly Cys Phe Val Cys Ala Cys Asn His Ser Gly Glu Glu Thr

35 40 45Asn Ala Lys Leu Lys Gln Thr Leu Glu Phe Ala Gly Asp Ser Arg Asn

505560 His Arg Thr Gln Trp Glu Asn His Arg Pro Ser His Gln Ala 657075 (2) SEQ ID NO:573 information

Sequence properties:

(A) length: 61 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 61

(xi) sequence representation: SEQ ID NO 573 Asn Leu Pro Val Ile Gln Gly Ile Ile Ala Pro Asn Gly Lys Ile Ile 151015 Ala Gln Ala Thr Lys Leu Asn Glu Val Ile Ile Ala Glu Met Asp Leu

20 25 30Asn Glu Val Ala Leu Gln Arg Gln Lys Ile Pro Tyr Leu Gln Asp Phe

35 40 45Asp Thr Lys Leu Thr Lys Lys Gly Phe Gly Lys Leu Thr

505560 (2) SEQ ID NO:574 information

Sequence properties;

(A) length: 162 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 162

(xi) sequence representation: SEQ ID NO:574: Ile Ile Met Phe Gly Met Gly Phe Phe Glu Ile Leu Val Val Leu Ile 151015 Val Ala Ile Ile Phe Leu Gly Pro Glu Lys Phe Pro Gln Ala Val Val

20 25 30Asp Ile Val Lys Phe Phe Arg Ala Val Lys Lys Thr Leu Asn Asp Ala

35 40 45Lys Asp Thr Leu Asp Lys Glu Ile Asn Ile Glu Glu Ile Lys Lys Glu

50 55 60Thr Leu Glu Tyr Gln Lys Leu Phe Glu Asn Lys Val Glu Ser Leu Lys65 70 75 80Gly Val Lys Ile Glu Glu Leu Glu Asp Ala Lys Val Thr Ala Glu Asn

85 90 95Glu Ile Lys Ser Ile Gln Asp Leu Met Gln Asp Tyr Lys Arg Ser Leu

100 105 110Glu Thr Asn Thr Ile Pro Asn His Leu Asn Glu Glu Val Ser Asn Glu

115 120 125Glu Ala Leu Asn Lys Glu Val Ser Ser Asp Glu Ser Pro Lys Glu Val

130135140 Gln Leu Thr Thr Asp Asn Asn Ala Lys Glu His Asp Lys Glu Lys Glu 145150155160 His Val (2) SEQ ID NO:575 message

Sequence properties:

(A) length: 185 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 185

(xi) sequence representation: SEQ ID NO 575: Arg Tyr Arg Ser Phe Ser Arg Asn Gln Ser Asn Phe Arg Arg Cys Glu 151015 Gln Pro Tyr Gly Ser Thr Leu Asn Ser Val Pro Leu Trp Ile Met Val

20 25 30Val Gly Ala Ala Gly Ile Ala Leu Gly Leu Ser Leu Tyr Gly Pro Lys

35 40 45Leu Ile Lys Thr Val Gly Ser Glu Ile Thr Glu Leu Asp Lys Met Gln

50 55 60Ala Phe Cys Ile Ala Leu Ser Ala Val Ile Thr Val Leu Leu Ala Ser65 70 75 80Gln Leu Gly Leu Pro Val Ser Ser Thr His Ile Val Val Gly Ala Val

85 90 95Phe Gly Val Gly Phe Leu Arg Glu Arg Leu Arg Glu Gln Ser Arg Arg

100 105 110Arg Phe Ala Arg Ile Arg Asp Asn Ile Val Ala Ala His Phe Gly Glu

115 120 125Asp Leu Glu Glu Ile Glu Gly Phe Leu Glu Arg Phe Asp Lys Ala Asn

130 135 140Leu Lys Glu Lys Ser Leu Met Leu Glu Ser Leu Lys Lys Ser Lys Asn145 150 155 160Thr Ala Ile Ala Leu Glu Leu Lys Lys Lys Asp Lys Lys Ser Leu Lys

165170 175Lys Val Tyr Lys Glu Glu Val Ile Lys

180185 (2) SEQ ID NO 576 information

Sequence properties:

(A) length: 105 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 105

(xi) sequence representation: SEQ ID NO 576: Ala Gln Ile Phe Val Arg Phe Asn Tyr Val Leu Gly Ala Ile Gly Phe 151015 Val Val Leu Leu Tyr Glu Ile Ile Ser Phe Ile Tyr Tyr Lys Arg Ser

20 25 30Leu Val Tyr Leu Ile Leu Gly Val Ala Ile Gly Ala Leu Cys Leu Leu

35 40 45Phe Val Phe Tyr Tyr Thr Pro Tyr Ile Leu Asn Ala Gln Lys Val Gly

50 55 60Glu Val Ala Leu Gln Ser Ala Glu Phe Ala Arg Ser His Ala Gln Ser65 70 75 80Glu Trp Leu Phe Lys Glu Leu Phe Val Leu Val Cys Ala Leu Phe Phe

85 90 95Trp Arg Leu Phe Gly Lys Asn Ala Leu

100105 (2) SEQ ID NO 577 message

Sequence properties:

(A) length: 116 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 116

(xi) sequence representation: SEQ ID NO 577: Lys Ala Cys Lys Met Lys Cys Ser Ser Phe Thr Ser Asn Ser Val Leu 151015 Asn Phe Phe Val Val Leu Ser Phe Ile Thr Ile Gly Leu Val Phe Phe

20 25 30Phe Leu Arg Ser Gln Pro Thr Ser Val Val Ser Lys Glu Asn Ile Pro

35 40 45Lys Ile Glu Leu Glu Asn Phe Lys Ala Phe Gln Ile Asn Asp Lys Ile

50 55 60Leu Asp Leu Ser Ile Glu Gly Lys Lys Ala Leu Gln Tyr Asp Asp His65 70 75 80Glu Ile Phe Phe Asp Ser Lys Ile Lys Arg Tyr Asp Glu Asp Thr Ile

85 90 95Glu Ser Val Glu Ser Pro Glu Ala Lys Arg Gln Gln Asp Leu Tyr Phe

100 105 110Phe Pro Asn Gly

115(2) SEQ ID NO 578 message

Sequence properties:

(A) length: 105 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 105

(xi) sequence representation: SEQ ID NO 578: Asn Gln Thr Lys Pro Glu Arg Lys Glu Lys Ile Pro His Phe Gln Arg 151015 Arg Val Leu Met Arg Trp Trp Cys Phe Leu Val Cys Cys Leu Ser Val

20 25 30Leu Ser Val Met Asp Ala Lys Lys Leu Glu Asn Lys Gly Leu Lys Lys

35 40 45Glu Arg Glu Leu Leu Glu Ile Thr Gly Asn Gln Phe Val Ala Asn Asp

50 55 60Lys Thr Lys Thr Ala Val Ile Gln Gly Asn Val Gln Ile Lys Lys Gly65 70 75 80Lys Asp Arg Leu Phe Ala Asp Lys Val Ser Val Phe Leu Asn Asp Lys

85 90 95Arg Lys Pro Glu Arg Tyr Glu Ala Ala

100105 (2) SEQ ID NO 579 message

Sequence properties:

(A) length: 319 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 319

(xi) sequence representation: SEQ ID NO 579: Lys Glu Ser Asn Ser Met Asp Leu Asp Lys Leu Lys Asp Tyr Arg Ala 151015 Leu Arg Asn Ala Ile Leu Arg Leu Leu Pro Tyr Leu Asp Ser Gly Ile

20 25 30Thr Glu Leu Ile Met Asn Lys Glu Lys Glu Ile Trp Leu Tyr Lys Leu

35 40 45Asn Gly Val Arg Glu Lys Val Phe Asp Glu Asn Leu Asp Lys Ala Phe

50 55 60Ile Leu Gly Phe Gly Glu Gln Leu Ala Ser Phe Arg Asp Leu Phe Phe65 70 75 80Asn Ala Asn Tyr Pro Thr Leu Asn Thr Ser Ile Pro Thr Ser Arg Tyr

85 90 95Arg Val Ser Met Asn His Phe Ala Ile Ser Ala Asp Asn Glu Leu Ser

100 105 110Leu Asn Ile Arg Val Pro Ser Asp Lys Lys Phe Asp Leu Lys Ala Phe

115 120 125Lys Leu Ser Ser Ile Cys Gln Tyr Asp Tyr Glu Tyr Leu Lys Asn Leu

130 135 140Met Ile Asp Gly Lys Asn Leu Leu Ile Ser Gly Gly Thr Gly Ser Gly145 150 155 160Lys Thr Ser Phe Leu Asn Ala Leu Ile Glu Phe Ile Pro Lys His Thr

165 170 175Aru Ile Val Ser Val Glu Asp Ser Glu Glu Leu Asp Leu Arg Ala Phe

180 185 190Glu Asn His Lys Ser Leu Leu Val Asp Lys Thr Glu Ser Ser Lys Phe

195 200 205Thr Tyr Glu Asn Ala Leu Asn Met Ala Met Arg Met Ser Pro Asp Arg

210 215 220Leu Met Val Gly Glu Ile Asp Thr Arg Asn Ser Met Leu Phe Leu Arg225 230 235 240Phe Gly Asn Thr Gly His Lys Gly Met Val Ser Thr Leu His Ala Asp

245 250 255Ser Val His Gly Val Ile Glu Ala Ile Ala Leu Asn Leu Gln Met Asn

260 265 270Lys Ser Gly Leu Asp Val Asn Val Ala Lys Lys Phe Phe Lys Ser Ser

275 280 285Val Asp Val Val Val Gln Ile Val Leu Asp Lys Ala Thr Asn Thr Arg

290295300 Tyr Ile Gln Glu Ile Leu Pro Ala Lys Asp Leu Arg Asp Ser Leu 305310315 (2) SEQ ID NO:580 information

Sequence properties:

(A) length: 87 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 87

(xi) sequence representation: 580: Gly Val Lys Ala Met Asn Tyr Asp Val Leu Met Gly Phe Leu Ala Leu 151015 Ile Leu Leu Ile Leu Trp Tyr Ala Tyr Gly Leu Arg Gln Tyr Leu Lys SEQ ID NO

20 25 30Leu Lys Asp Lys Asn Lys Arg Leu Lys Glu Lys Leu Gln Arg Cys Asn

35 40 45Cys Asn Ile Lys Ile Pro Ser Ile Leu Glu Met Ala His Lys Pro Ile

50 55 60Ile Met Asp Ile Lys Gly Glu Leu Leu Pro His Leu Thr Glu Ser Tyr65 70 7580Arg Lys Ser Lys Phe Lys Glu

85(2) SEQ ID NO:581 information

Sequence properties:

(A) length: 95 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 95

(xi) sequence representation: 581 ID NO: Leu Ser Arg Asn Gly Val Val Ser Ser Val Ser Ser Asp Gly Ser Lys 151015 Ile Leu Met Ser Leu Ala Pro Asp Gly Gln Pro Asp Val Tyr Leu Tyr

20 25 30Asp Thr His Lys Lys Thr Lys Thr Lys Ile Thr Arg Tyr Pro Gly Ile

35 40 45Asp Val Ser Gly Val Phe Leu Glu Asp Asp Lys Ser Met Ala Phe Val

50 55 60Ser Asp Arg Ser Gly Tyr Pro Asn Ile Tyr Met Lys Lys Leu Gly Leu65 70 75 80Lys Glu Arg Arg Ser Asn Ser Phe Met Lys Glu Glu Ala Met Asn

859095 (2) SEQ ID NO:582 information

Sequence properties:

(A) length: 146 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 146

(xi) sequence representation: 582: Gly Asp Lys Met Leu Lys Lys Leu Leu Leu Ile Ser Leu Phe Leu Gly 151015 Phe Leu Arg Ala Glu Gly Glu His Tyr Glu Ile Ile Ala Glu Leu Ser SEQ ID NO

20 25 30Lys Ala Phe Leu Lys Ala Lys Glu Val Leu Thr Ala Ile Asn Lys Thr

35 40 45Tyr Lys Thr Cys Ile Glu Thr Gly His Asp Arg Thr Gln Ile Arg Leu

50 55 60Gln Asn Asp Phe Leu Glu Asn Leu Ser Gln Thr Glu Gln Gln Phe Asp65 70 75 80Asp Tyr Phe Glu Lys Asp Phe Lys Ser Val Gly Val Leu Lys Thr Leu

85 90 95Leu Lys Asp Ile Gln Ser Leu Glu Lys Thr Ser Asn Lys Leu Val Cys

100 105 110Val Ala Pro Lys Asn Ala Lys Asn Phe Glu Ile Leu Glu Gly Ala Ile

115 120 125Thr Gln Ile Ile Gly Leu Glu Glu Gln Met Asn Gln Phe Ile Asn Gly

130135140 Ala Lys145(2) SEQ ID NO 583 message

Sequence properties:

(A) length: 115 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 115

(xi) sequence representation: 583: Ile Gln Arg Leu Lys Glu Met Leu Arg Asn Gln Phe Arg Ile Val Phe 151015 Val Thr Cys Ile Val Ala Ser Ser Leu Gln Ala Gln Glu Asn Thr Pro SEQ ID NO

20 25 30Thr Leu Gly Lys Val Thr Thr Lys Gly Glu Arg Thr Phe Glu Tyr Asn

35 40 45His Gln Met Tyr Thr Asp Arg Lys Glu Leu Gln Gln Arg Gln Ser Asn

50 55 60Gln Thr Arg Asp Ile Phe Arg Thr Arg Ala Asp Val Asn Ala Ala Ser65 70 75 80Gly Gly Leu Met Ala Gln Lys Ile Tyr Ala Arg Gly Ile Glu Ser Arg

85 90 95Leu Leu Arg Val Thr Ile Asp Gly Val Ala Gln Asn Gly Asn Ile Phe

100 105 110His His Asp

115(2) SEQ ID NO 584 information

Sequence properties;

(A) length: 264 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position:1 … 264

(xi) sequence representation: 584: Ala Val Ser Trp Ile Met Ala Cys Trp His Lys Arg Leu Ala Val Gly 151015 Cys Cys Ile Val Leu Leu Ser Cys Val Met Sar Ala Asn Asn Val Ser SEQ ID NO

20 25 30Ile Val Arg Asp Asp Pro Pro Leu Asp Pro Thr Leu Pro Ala Trp Ile

35 40 45Tyr Ser Val Ala Leu Leu Lys Val Tyr Phe Ser Asp Gly Thr Tyr Lys

50 55 60Glu Gly Tyr Ala Thr Leu Leu Glu Asn Gly Arg Tyr Ile Ala Ser Ser65 70 75 80Glu Thr Leu Tyr Ser Asn Gly Leu Tyr Pro Lys Met Ile Leu Ala Lys

85 90 95Met Gln Asp Ser Ser Ala Lys Glu Leu Ile Cys Ile Ala Ser Leu His

100 105 110Leu Glu Ala Met Asp Arg Asp Gln Gly Leu Ser Leu Leu Lys Thr Ala

115 120 125Asp Phe Arg Asp Asp Tyr Cys His Lys Arg Glu Glu Ser Tyr Tyr His

130 135 140Ala Arg Ile Tyr Ala Lys Tyr Ala Gln Thr Phe His Ser Asn Pro Tyr145 150 155 160Thr Asn Gln Lys Thr Pro Thr Ser Asp Leu Tyr Tyr Pro Ala Leu Asn

165 170 175Glu Gly Asn Ser Phe Ser Ile Gln Thr Thr Asp Ile Ser Val Ala Glu

180 185 190Leu Leu Lys Ser Lys Lys Phe Leu Ser Leu Asp Ala Ser Phe Lys Lys

195 200 205Gly Ser Val Leu Trp Gly Gly Arg Pro Tyr Phe Ser Glu Val Gly Glu

210 215220Phe Met Gly Met Thr Ser Ser Thr Leu Glu Asn Gln Glu Ser Leu Val225 230 235 240Ile Ile Pro Lys Glu Lys Ile Ala Arg Phe Leu Ser Ala Leu Lys Asn

245 250 255Gln Asn Ile Phe Pro Asn Ile Pro

260(2) SEQ ID NO 585 information

Sequence properties:

(A) length: 147 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 147

(xi) sequence representation: SEQ ID NO:585: Leu Gly Gly Leu Asp Met Tyr Lys Leu Gly Ile Phe Leu Leu Ala Thr 151015 Leu Leu Ser Ala Asn Thr Gln Lys Val Ser Asp Ile Ala Lys Asp Ile

20 25 30Gln His Lys Glu Thr Leu Leu Lys Lys Thr His Glu Glu Lys Asn Gln

35 40 45Leu Asn Ser Arg Leu Ser Ser Leu Gly Glu Ala Ile Arg Ser Lys Glu

50 55 60Leu Gln Lys Val Glu Ile Glu Arg Gln Met Val Ala Leu Lys Lys Ser65 70 75 80Leu Glu Lys Asn Arg Asn Glu Ser Leu Val Gln Glu Lys Val Leu Thr

85 90 95Asn Tyr Arg Lys Ser Leu Asp His Leu Gln Lys Gln Arg Ser Phe Leu

100 105 110Gln Lys Arg Val Phe Asp Thr Leu Leu Glu Asp Phe Leu Phe Ser Gln

115 120 125Ala Leu Lys Gly Gln Asn Leu Ala Ser Ser Asn Asp Val Ile Leu Leu

130135140 Ser Gly Val145(2) SEQ ID NO:586 information

Sequence properties;

(A) length: 523 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 523

(xi) sequence representation: 586 SEQ ID NO: Tyr Ile Pro Phe Asn Leu Phe Gln Gly Gln Thr Asn Met Lys Lys Leu 151015 Leu Tyr Thr Met Leu Ala Leu Leu Leu Ile Gly Leu Leu Thr Ala Tyr

20 25 30Leu Ile Leu Phe Thr Glu Trp Gly Asn Lys Ile Ile Ala Ser Tyr Ile

35 40 45Glu Lys Lys Ile Asn Pro Asn Glu Arg Tyr Leu Ser Val Lys Thr Phe

50 55 60Lys Leu Arg Phe Asn Ser Leu Asp Phe Lys Ala Gln Ala Asn Asp Asp65 70 75 80Ser Thr Leu Ile Leu Lys Gly Asp Phe Ser Leu Leu Thr Gln Ser Val

85 90 95Asn Leu Asp Tyr His Ile Asp Ile Lys Asn Leu Arg Ser Phe Lys Asp

100 105 110Leu Ile Pro Tyr Pro Leu Arg Gly Ala Ile Val Thr Ser Gly Asn Ile

115 120 125Lys Gly His Arg Lys Ala Leu Val Val Gln Gly Val Ser Asn Val Ala

130 135 140Gln Ser His Thr Ala Tyr Asn Ala Leu Leu Asp Asp Phe Lys Leu Ser145 150 155 160His Leu Ser Leu Asn Ala Lys Asp Ala Asn Leu Glu Asp Leu Leu Tyr

165 170 175Leu Ile Asn Arg Pro Ala Tyr Ala Asn Ala Lys Val Ser Leu Gln Ala

180 185 190Asp Phe Asn Ser Leu Lys Pro Leu Glu Gly His Leu Ile Leu Thr Ala

195 200 205Asn Asn Ala Leu Ile Asn Asn Ala Leu Ile Asn Gln Ile Phe His Leu

210 215 220Asn Leu Lys Asp Thr Leu Val Phe Asn Leu Ser His Ser Ser Asp Phe225 230 235 240Lys Gly Asn Lys Ala Ile Ser Asp Thr Thr Leu Thr Ser Pro Leu Val

245 250 255Asn Phe Thr Ala Leu Lys Ser Glu Tyr Ser Phe Pro Ala Leu Lys Leu

260 265 270 Asn Ala Pro Tyr Thr Leu Glu Ile Pro His Leu Ala Lys Leu Gln Asn

275 280 285Ile Thr Asn His Pro Leu Lys Gly Ser Leu Thr Leu Lys Gly Asp Ile

290 295 300Glu Gln Ser Pro Lys Leu Leu Lys Val Ser Gly His Ser Asn Leu Leu305 310 315 320Asp Gly Ala Leu Asp Phe Thr Leu Leu Asn Lys Asp Leu Lys Ala Arg

325 330 335Phe Ser Asn Ile Ser Thr Ser Lys Ala Leu Asp Leu Phe His Tyr Pro

340 345 350Lys Phe Phe Gln Ser Ile Ala Asp Ala Asn Leu Asp Tyr Asp Leu Ile

355 360 365Ser Lys Gln Gly Val Leu Lys Ala Asn Leu Lys Asn Ala Arg Phe Leu

370 375 380Lys Asn Ala Phe Ser Asp Phe Leu Tyr Ser Ile Ser Arg phe Asp Ile385 390 395 400Thr Lys Glu Ile Tyr His Asp Ala Asn Leu Val Ser Gln Ile Asn Gln

405 410 415Gln Arg Leu Leu Ser Asp Leu Ser Leu Lys Ser Pro Lys Thr Gln Leu

420 425 430Lys Ile His Asn Gly Leu Leu Asp Leu Asn Thr Lys Gln Met Asp Ile

435 440 445Leu Met Asp Ala Glu Ile Leu Lys Phe Ile Phe Lys Met Lys Leu Gln

450 455 460Gly Ser Met His Gln Pro Lys Phe Ser Leu Ile Leu Asn Glu Lys Ala465 470 475 480Ile Gln Gln Asn Leu Gln Gln Gly Leu Lys Glu Ile Leu Lys Asn Asp

485 490 495Thr Leu Lys Lys Gly Leu Asp His Leu Leu Lys Asp Asp Lys Leu Lys

500 505 510Glu Lys Leu Glu Lys Gly Leu Lys Gly Leu Phe

515520 (2) information of SEQ ID NO 587

Sequence properties:

(A) length: 222 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 222

(xi) sequence representation: 587: Ala Phe Leu Tyr Ile His Ser Ile Ala Leu Ala Arg Val Ile Leu Gln 151015 Leu Lys Pro Leu Leu Thr Ile His Leu Asn Ala Lys Ser Gln Ser Ser SEQ ID NO

20 25 30Leu Lys Asn Lys Ile Thr Leu Lys Asn Lys Leu Asn His Ala Arg Ile

35 40 45Ile Leu Glu Phe Ile Pro Ser Leu Ile Tyr Phe Leu Ile Gln Lys Val

50 55 60Ser Val Leu Lys His Leu Ala Pro Leu Ile His Ile Pro Phe Lys Ala65 70 75 80Leu Trp Leu Gly Thr Ala Leu Ser Met Phe Leu Ser Leu Asn Leu Asn

85 90 95Ala Glu Glu Asn Pro Thr Lys Thr Glu Pro Lys Pro Ala Lys Gly Val

100 105 110Lys Asn Lys Pro Lys Ser Pro Val Thr Asn Val Met Met Thr Asn Cys

115 120 125Asp Asn Leu Lys Asp Phe Asn Ala Lys Gln Lys Glu Val Leu Lys Ala

130 135 140Ala Tyr Gln Phe Gly Ser Thr Glu Asn Leu Gly Tyr Glu Met Ala Gly145 150 155 160Ile Ala Trp Lys Glu Ser Cys Ala Gly Thr Tyr Lys Ile Asn Phe Ser

165 170175Asn Pro Ser Ala Gly Ile Tyr His Ala Tyr Ile Pro Ser Val Leu Lys

180 185 190Ser Tyr Gly His Asn Asn Ser Pro Phe Leu Arg Asn Val Met Gly Arg

195 200 205Ile Ala Thr Leu Lys Thr Met Arg Leu Leu Leu Lys Trp Pro

210215220 (2) SEQ ID NO 588 information

Sequence properties:

(A) length: 299 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 299

(xi) sequence representation: SEQ ID NO 588: Leu Val Ile Ile Ser Leu Leu Thr Thr Leu Lys Leu Lys Ser Ile Lys 151015 Glu Ile Ser Ile Lys Lys Phe Ile Leu Ser Ser Leu Val Phe Ala Cys

20 25 30Ile Asn Thr Gly Val Glu Ala Leu Glu Asn Asp Gly Ser Lys Pro Asn

35 40 45Asp Leu Ala Ser Pro Lys Glu Thr Pro Lys Glu Ala Gln Lys Asn Glu

50 55 60Ala Gln Asn Glu Thr Ser Gln Ser Asn Gln Thr Pro Lys Glu Met Lys65 70 75 80Val Lys Ser Ile Ser Tyr Val Gly Leu Ser Tyr Met Ser Asp Met Leu

85 90 95Ala AsnGlu Ile Ala Lys Ile Arg Val Gly Asp Met Val Asp Ser Lys

100 105 110Lys Ile Asp Thr Ala Val Leu Ala Leu Phe Asn Gln Gly Tyr Phe Lys

115 120 125Asp Val Tyr Ala Thr Phe Glu Asn Gly Ile Leu Glu Phe His Phe Asp

130 135 140Glu Lys Ala Arg Ile Ala Gly Val Glu Ile Lys Gly Tyr Gly Thr Glu145 150 155 160Lys Glu Lys Asp Gly Leu Lys Ser Gln Met Gly Ile Lys Lys Gly Asp

165 170 175Thr Phe Asp Glu Gln Lys Leu Glu His Ala Lys Thr Ala Leu Lys Thr

180 185 190Ala Leu Glu Gly Gln Gly Tyr Tyr Gly Ser Val Val Glu Val Arg Thr

195 200 205Glu Lys Val Ser Glu Gly Ala Leu Leu Ile Val Phe Asp Val Asn Arg

210 215 220Gly Asp Ser Ile Tyr Ile Lys Gln Ser Ile Tyr Glu Gly Ser Asp Lys225 230 235 240Leu Lys Arg Arg Val Ile Glu Ser Leu Ser Ala Asn Lys Gln Arg Asp

245 250 255Phe Met Gly Trp Met Trp Gly Leu Asn Asp Gly Lys Leu Arg Leu Asp

260 265 270Gln Leu Glu Tyr Asp Ser Leu Arg Ile Gln Asp Val Tyr Met Arg Arg

275 280 285Gly Tyr Leu Asp Ala His Ile Ser Ser Pro Phe

290295 (2) information of SEQ ID NO 589

Sequence properties:

(A) length: 288 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 288

(xi) sequence representation: 589: Glu Phe Gly Val Lys Arg Ile Leu Phe Phe Leu Ala Ala Thr Thr Phe 151015 Leu Leu Arg Ala Glu Thr Ala Ser Ala Thr Ile Asn Thr Thr Val Asp SEQ ID NO

20 25 30Pro Asn Val Met Phe Ser Glu Ser Ser Thr Gly Asn Val Lys Lys Asp

35 40 45Arg Lys Arg Val Leu Lys Ser Met Val Asp Leu Glu Lys Glu Arg Val

50 55 60Lys Asn Phe Asn Gln Tyr Ser Glu Thr Lys Met Ser Lys Gly Asp Leu65 70 75 80Ser Ala Phe Gly Ala Phe Phe Lys Gly Ser Leu Glu Asp Cys Val Glu

85 90 95Gln Lys Ile Cys Tyr Tyr Glu His Arg Asn Gly Lys Val Ser Phe Val

100 105 110Val Asn Asp Arg Glu Lys Phe Tyr Lys His Val Leu Lys Asp Leu Gly

115 120 125Thr Glu Leu Ser Leu Pro Leu Phe Asn Trp Leu Tyr Lys Gly Ser Asp

130 135 140Phe Gly Ala Leu His Glu Gln Phe Gly Asp Met Tyr Asp Gly Tyr Ile145 150 155 160Lys Tyr Leu Ile Ser Met Val Arg Val Ser Gln Lys Glu Lys Ala Arg

165 170 175Lys Val Asp Ala Ile Val Leu Lys Lys Met Glu Glu Gln Ala Glu Lys

180 185 190Asp Thr Lys Ala Ala Phe Gln Lys Arg Ser Ser Gly Glu Leu Glu Ser

195 200 205His Thr Asp Ser Pro Glu Phe Ile Ser Ser Ser Lys Thr Gln Asn Ser

210 215 220Ser Asn Pro Asp Leu Asp Pro Met Thr Asn Ala Asn Thr Leu Lys Glu225 230 235 240Thr Ala Ser Lys Glu Pro Glu Thr Ser Ser Lys Lys Glu Lys Lys Pro

245 250 255Lys Lys Lys Arg Arg Leu Ser Lys Lys Glu Lys Gln Gln Gln Ala Leu

260 265 270Gln Gln Glu Phe Glu Lys Gln Ile Ser Asp Ser Ser Lys Ser Glu Lys

275280285 (2) SEQ ID NO 590 message

Sequence properties:

(A) length: 407 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 407

(xi) sequence representation: 590: Ser Arg Thr Leu Cys Ala Lys Ile Val Leu Gln Lys Glu Arg Lys Lys 151015 Met Glu Ile Gln Gln Thr His Arg Lys Ile Asn Arg Pro Leu Val Ser SEQ ID NO

20 25 30Leu Val Leu Ala Gly Ala Leu Ile Ser Ala Ile Pro Gln Glu Ser His

35 40 45Ala Ala Phe Phe Thr Thr Val Ile Ile Pro Ala Ile Val Gly Gly Ile

50 55 60Ala Thr Gly Thr Ala Val Gly Thr Val Ser Gly Leu Leu Ser Trp Gly65 70 75 80Leu Lys Gln Ala Glu Glu Ala Asn Lys Thr Pro Asp Lys Pro Asp Lys

85 90 95 Val Trp Arg Ile Gln Ala Gly Lys Gly Phe Asn Glu Phe Pro Asn Lys

100 105 110Glu Tyr Asp Leu Tyr Lys Ser Leu Leu Ser Ser Lys Ile Asp Gly Gly

115 120 125Trp Asp Trp Gly Asn Ala Ala Arg His Tyr Trp Val Lys Gly Gly Gln

130 135 140Trp Asn Lys Leu Glu Val Asp Met Lys Asp Ala Val Gly Thr Tyr Lys145 150 155 160Leu Ser Gly Leu Arg Asn Phe Thr Gly Gly Asp Leu Asp Val Asn Met

165 170 175Gln Lys Ala Thr Leu Arg Leu Gly Gln Phe Asn Gly Asn Ser Phe Thr

180 185 190Ser Tyr Lys Asp Ser Ala Asp Arg Thr Thr Arg Val Asn Phe Asn Ala

195 200 205Lys Asn Ile Ser Ile Asp Asn Phe Val Glu Ile Asn Asn Arg Val Gly

210 215 220Ser Gly Ala Gly Arg Lys Ala Ser Ser Thr Val Leu Thr Leu Gln Ala225 230 235 240Ser Glu Gly Ile Thr Ser Ser Lys Asn Ala Glu Ile Ser Leu Tyr Asp

245 250 255Gly Ala Thr Leu Ash Leu Ala Ser Asn Ser Val Lys Leu Asn Gly Asn

260 265 270Val Trp Met Gly Arg Leu Gln Tyr Val Gly Ala Tyr Leu Ala Pro Ser

275 280 285Tyr Ser Thr Ile Asn Thr Ser Lys Val Gln Gly Glu Val Asp Phe Asn

290 295 300His Leu Thr Val Gly Asp Gln Asn Ala Ala Gln Ala Gly Ile Ile Ala305 310 315 320Ser Asn Lys Thr His Ile Gly Thr Leu Asp Leu Trp Gln Ser Ala Gly

325 330 335Leu Asn Ile Ile Ala Pro Pro Glu Gly Gly Tyr Lys Asp Lys Pro Asn

340 345 350Ser Thr Thr Ser Gln Ser Gly Thr Lys Asn Asp Lys Lys Glu Ile Ser

355 360 365Gln Asn Asn Asn Ser Asn Thr Glu Val Ile Asn Pro Pro Asn Asn Thr

370 375 380Gln Lys Thr Glu Thr Glu Pro Thr Lys Ser Leu Met Gly Leu Leu Leu385 390 395 400Lys Ala Lys Thr Arg Leu Ser

405(2) information SEQ ID NO:591

Sequence properties:

(A) length: 163 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 163

(xi) sequence representation: 591: Gln Ile Phe Cys Ser Thr Gln Ser Ser Lys Leu Pro Leu Lys Lys Ala 151015 Pro Lys Ala Asp Lys Ser Pro Leu Leu Ile Leu Val Ser Glu Tyr Trp SEQ ID NO

20 25 30Leu Lys Phe Phe Thr Arg Ser Phe Ser Lys Ser Thr Met Leu Phe Lys

35 40 45Thr Leu Leu Arg Ser Phe Phe Thr Phe Pro Val Glu Leu Ser Glu Asn

50 55 60Ile Thr Leu Gly Ser Thr Val Val Leu Ile Val Ala Glu Ala Val Ser65 70 75 80Ala Leu Asn Lys Lys Val Val Ala Ala Lys Lys Asn Lys Ile Arg Phe

85 90 95Thr Pro Asn Ser Tyr Ile His Asn Arg Asn Lys Asn Arg Arg Tyr Ser

100 105 110Ser Leu Ser Pro Leu Leu Lys Ser Ser Ser Ile Cys Lys Asn Pro Pro

115 120 125Arg Ile Gln Ala Ile Leu Ile Ile Leu Lys Tyr Arg Leu Ser Lys Gly

130135140 Phe Asn Pro Val Val Val Ile Leu Arg Ile Gln Lys Met Arg Thr Leu 145150155160 Gln Lys Leu (2) SEQ ID NO:592 information

Sequence properties:

(A) length: 201 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 201

(xi) sequence representation: 592 SEQ ID NO: Gly Leu Ile Thr Met Asp Lys Asn Asn Asn Asn Asn Leu Arg Leu Ile 151015 Leu Ala Ile Ala Leu Ser Phe Leu Leu Ile Ala Leu Asn Ser Tyr Phe

20 25 30Phe Gln Glu Pro Asn Lys Thr Thr Thr Glu Thr Thr Lys Gln Glu Thr

35 40 45Thr Asn Asn His Thr Ala Thr Ser Pro Thr Ala Ser Asn Thr Ile Thr

50 55 60Gln Asp Phe Ser Val Thr Gln Thr Ile Pro Gln Glu Ser Leu Leu Ser65 70 75 80Thr Ile Ser Phe Glu His Ala Lys Ile Glu Ile Asp Ser Leu Gly Arg

85 90 95Ile Lys Gln Val Tyr Leu Lys Asp Lys Lys Tyr Leu Thr Pro Lys Glu

100 105 110Lys Gly Phe Leu Glu His Val Ser His Leu Phe Ser Ser Lys Glu Asn

115 120 125Ser Gln Pro Ser Leu Lys Glu Leu Pro Leu Leu Ala Ala Asp Lys Leu

130 135 140Lys Pro Leu Glu Val Arg Phe Leu Asp Pro Thr Leu Asn Asn Lys Ala145 150 155 160Phe Asn Thr Pro Tyr Ser Ala Ser Lys Thr Thr Leu Gly Pro Asn Glu

165 170 175Gln Leu Val Leu Thr Gln Asp Leu Gly Thr Leu Ser Ile Ile Lys Thr

180 185 190Leu Thr Phe Tyr Asp Asp Leu His Tyr

195200 (2) SEQ IDNO 593 information

Sequence properties:

(A) length: 68 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 68

(xi) sequence representation: SEQ ID NO 593: Gly Val Ser Ile Ile Met Val Leu Lys Thr Lys Leu Lys Ile Ile Ser 151015 Ser Val Ile Leu Ser Thr Leu Leu Trp Val Gly Cys Ser Ser Glu Met

20 25 30Ala Thr Tyr Gln Asn Val Asn Asp Ala Thr Lys Asn Thr Thr Ala Ser

35 40 45Ile Asn Ser Thr Asp Leu Leu Leu Thr Ala Asn Ala Met Leu Asp Ser

505560 Met Leu Gly Thr65(2) SEQ ID NO:594 information

Sequence properties:

(A) length: 176 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 176

(xi) sequence representation: SEQ ID NO 594: Ala Met Lys Asn Gln Val Lys Lys Ile Leu Gly Met Ser Val Val Ala 151015: Ala Met Val Ile Val Gly Cys Ser His Ala Pro Lys Ser Gly Ile Ser

20 25 30Lys Ser Asn Lys Ala Tyr Lys Glu Ala Thr Lys Gly Ala Pro Asp Trp

35 40 45Val Val Gly Asp Leu Glu Lys Val Ala Lys Tyr Glu Lys Tyr Ser Gly

50 55 60Val Phe Leu Gly Arg Ala Glu Asp Leu Ile Thr Asn Asn Asp Val Asp65 70 75 80Tyr Ser Thr Asn Gln Ala Thr Ala Lys Ala Arg Ala Asn Leu Ala Ala

85 90 95Asn Leu Lys Ser Thr Leu Gln Lys Asp Leu Glu Asn Glu Lys Thr Arg

100 105 110Thr Val Asp Ala Ser Gly Lys Arg Ser Ile Ser Gly Thr Asp Thr Glu

115 120 125Lys Ile Ser Gln Leu Val Asp Lys Glu Leu Ile Thr Ser Lys Met Leu

130 135 140Ala Arg Tyr Val Gly Lys Asp Arg Val Phe Val Leu Val Gly Leu Asp145 150 155 160Lys Gln Ile Val Asp Lys Val Arg Glu Glu Leu Gly Met Val Lys Lys

165170175 (2) information of SEQ ID NO:595

Sequence properties:

(A) length: 100 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 100

(xi) sequence representation: 595: Pro Lys Pro Tyr Ala Val Ser Ile Leu Cys Ile Cys Val Met Phe Ile 151015 Leu Phe Lys Phe Gly Arg Val Leu Gly Lys Ala Tyr Ser Leu Tyr Leu SEQ ID NO

20 25 30Tyr Ile Tyr Glu Ser Leu Ile Cys Gln Ala Phe Gly Leu Ser Leu Ser

35 40 45Cys Asn Asn Ser Met Leu Phe Ser Thr Phe Leu Ile Asn Leu Pro Leu

50 55 60Pro His Asn Glu Ser Leu Cys Cys Cys Arg Asp Ile Leu Ala Tyr Ser65 70 75 80Asn Ser Ser Ser Leu Lys Thr Tyr Ser Leu Glu Ser Asn Phe Ser Phe

85 90 95Asn Ser Leu Phe

100(2) SEQ ID NO 596 information

Sequence properties:

(A) length: 100 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 100

(xi) sequence representation: SEQ ID NO 596: Thr Ala Arg Met Asn Arg Met Lys Pro Ile Phe Leu Leu Ile Phe Leu151015 Leu Leu Ala Ser Leu Ile Ala Arg Glu Lys Asp Ala Ser Ser Asn Leu

20 25 30Phe Asp Leu Ile Asp Lys Gly Ile Asn Arg Glu Gln Glu Leu Lys Glu

35 40 45Gln Glu Gln Lys Thr Arg Leu Lys Leu Ala Gln Ser Pro Leu Val Ala

50 55 60Leu Glu Ile Val Pro Gln Glu Thr Pro Tyr Leu Glu Trp Gln Gly Ala65 70 75 80Arg Glu Ser Tyr Tyr Leu Lys Val Glu Arg Cys Ser Gly Glu Arg Gly

85 90 95Tyr Phe Lys Asp

100(2) SEQ ID NO 597 information

Sequence properties:

(A) length: 231 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 231

(xi) sequence representation: SEQ ID NO 597: Val Ala Arg Ala Phe Ile Ala Leu Tyr Ala Ile Ser Ala Val Asn Lys 151015 Ser Lys Val Glu Ala Leu Lys Thr Glu Phe Ile Lys Ile Phe Asn Tyr

20 25 30Ala Pro Lys Pro Glu Ala Met Gln Pro Val Val Val Ile Pro Pro Asp

35 40 45Ser Gly Lys Glu Glu Glu Gln Met Ala Ser Glu Ser Ser Lys Pro Ala

50 55 60Ser Gln Asn Thr Glu Thr Lys Ala Thr Ile Ala Arg Lys Gly Glu Gly65 70 75 80Ser Val Leu Glu Gln Ile Asp Gln Gly Ser Val Leu Lys Leu Pro Ser

85 90 95Ser Leu Leu Phe Glu Asn Ala Thr Ser Asp Ala Ile Asn Gln Asp Met

100 105 110Met Leu Tyr Ile Glu Arg Ile Ala Lys Ile Ile Gln Lys Leu Pro Lys

115 120 125Arg Val His Ile Asn Val Arg Gly Phe Thr Asp Asn Thr Pro Leu Asn

130 135 140Lys Thr Arg Phe Lys Ser His Tyr Glu Leu Ala Ala Asn Arg Ala Tyr145 150 155 160Arg Val Met Lys Val Leu Ile Gln Tyr Gly Val Asp Pro Asn Gln Leu

165 170 175Ser Phe Ser Ser Tyr Gly Ser Thr Ash Pro Ile Ala Pro Asn Asp Ser

180 185 190Leu Glu Asn Arg Met Lys Asn Asn Arg Val Glu Ile Phe Phe Ser Thr

195 200 205Asp Ala Asn Asp Leu Ser Lys Ile His Ser Ile Leu Asp Glu Glu Phe

210215220 Asn Pro His Lys Gln Gln Glu 225230 (2) SEQ ID NO 598 information

Sequence properties:

(A) length: 98 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 98

(xi) sequence representation: 598 SEQ ID NO Gln Arg Leu Tyr Leu Gly Lys Leu Asn Ala Lys Val Asn His Thr Ile 151015 Phe Gln Phe Leu Val Asn Val Gly Ile Arg Thr Asn Ile Phe Glu His

20 25 30His Gly Ile Glu Phe Gly Ile Lys Ile Pro Thr Leu Pro Asn Tyr Phe

35 40 45Phe Lys G1y Ser Thr Thr Ile Arg Ala Lys Lys Gln Gly Pro Leu Glu

50 55 60Asn Gly Asn Pro Thr Thr Ile Thr Gly Ala Glu Thr Asn Phe Ser Leu65 70 75 80Thr Gln Thr Leu Arg Arg Gln Tyr Ser Met Tyr Leu Arg Tyr Val Tyr

859095 ThrPhe (2) SEQ ID NO 599 information

Sequence properties:

(A) length: 357 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 357

(xi) sequence representation: SEQ ID NO 599: Phe His Phe Tyr Cys Leu Tyr Phe Leu Asn Gly Gly Tyr Asn Arg Leu 151015 His Lys Ser Tyr Glu Arg Ile Val Met Leu Ile Ala Arg Phe Lys Lys

20 25 30Ala Leu Ile Ser Tyr Ser Leu Gly Val Leu Leu Val Ser Ser Leu Leu

35 40 45Gly Val Ala Asn Ala Ser Asn Gln Glu Ile Gln Val Lys Asp Tyr Phe

50 55 60Gly Glu Gln Thr Ile Lys Leu Pro Val Ser Lys Ile Ile Tyr Leu Gly65 70 75 80 Ser Phe Ala Glu Val Pro Ala Met Phe Asn Thr Trp Asp Arg Val Val

85 90 95Gly Ile Ser Asp Tyr Ala Phe Lys Ser Asp Ile Val Lys Ala Thr Leu

100 105 110Lys Asp Leu Glu Arg Ile Lys Pro Met Ser Ser Asp His Val Ala Ala

115 120 125Leu Asn Val Glu Leu Leu Lys Lys Leu Ser Pro Asn Leu Val Val Thr

130 135 140Phe Val Gly Asn Pro Lys Ala Val Glu His Ala Lys Lys Phe Gly Ile145 150 155 160Ser Phe Leu Ser Phe Gln Glu Lys Thr Ile Val Glu Val Met Glu Asp

165 170 175Ile Asp Ala Gln Ala Lys Ala Leu Glu Val Asp Ala Ser Lys Lys Leu

180 185 190Ala Lys Met Gln Glu Thr Leu Asp Phe Ile Lys Glu Arg Leu Lys Asn

195 200 205Val Lys Lys Lys Lys Gly Val Glu Leu Phe His Lys Ala Asn Lys Ile

210 215 220Ser Gly His Gln Ala Leu Asp Ser Asp Ile Leu Glu Lys Gly Gly Ile225 230 235 240Asp Asn Phe Gly Leu Lys Tyr Val Lys Phe Gly Arg Ala Asp Ile Ser

245250 255Val Glu Lys Ile Val Lys Glu Asn Pro Glu Ile Ile Phe Ile Trp Trp

260 265 270Val Ser Pro Leu Thr Pro Glu Asp Val Leu Asn Asn Pro Lys Phe Ser

275 280 285Thr Ile Lys Ala Ile Lys Asn Lys Gln Val Tyr Lys Leu Pro Thr Met

290 295 300Asp Ile Gly Gly Pro Arg Ala Pro Leu Ile Ser Leu Phe Ile Ala Leu305 310 315 320Lys Ala His Pro Glu Ala Phe Lys Gly Val Asp Ile Asn Ala Ile Ile

325 330 335Lys Asp Tyr Tyr Lys Val Val Phe Asp Leu Asn Asp Ala Glu Val Glu

340 345 350Pro Phe Leu Trp His

355(2) SEQ ID NO 600 message

Sequence properties:

(A) length: 61 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 61

(xi) sequence representation: 600: Asp His His Lys Glu Phe Arg Met Lys Lys Gln Ile Leu Thr Gly Val 151015 Leu Leu Ser Val Leu Ala Val Ser Ser Ala Tyr Ala His Lys Asp Lys SEQ ID NO

20 25 30Lys Asp Ala Lys Lys Pro Glu Leu SerSer Gln Leu Val Ala His Lys

35 40 45Asp Lys Lys Asp Ala Lys Lys Pro Lys Asn Ser Val Ala

505560 (2) SEQ ID NO 601 information

Sequence properties:

(A) length: 200 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 200

(xi) sequence representation: 601: Arg Ile Ile Lys Gly Asn Ile Met Ser Ser Gly Leu Ile Tyr Ile Ser 151015 Leu Glu Val Leu Val Ala Cys Leu Ile Thr Ala Leu Ile Met Tyr Tyr SEQ ID NO

20 25 30Val Met Lys Lys Ile Tyr Tyr Ala Arg Gly Gln Ala Ile Leu Lys Gly

35 40 45Ala Ser Ala Lys Ala Lys Leu Met Glu Phe Gln Ala Lys Ser Phe Val

50 55 60Glu Ala Glu Glu Met Arg Met Lys Ser Gln Glu Cys Lys Leu Gln Gln65 70 75 80Gln Tyr Glu Asn Lys Asn Leu Gln Leu Gln Thr His Phe Asp Lys Lys

85 90 95Glu Ala His Leu Lys His Leu Glu Ala Gln His Lys Glu Phe Val Arg

100 105 110Asp Glu Lys Arg Tyr Leu Glu Lys Glu Lys Lys Glu Leu Glu Lys Glu

115 120 125Arg Gln Ile Leu Glu Gln Glu Arg Glu Asn Phe Lys Lys Gln Arg Ala

130 135 140Ile Cys Lys Glu Ala Gln Ala Lys Ala Leu Asp Ala Met Leu Asn Tyr145 150 155 160Met Ala Tyr Thr Lys Asp Glu Ile Lys Ser Met Ile Leu Glu Gln Leu

165 l70 175Glu Gln Glu Leu Glu Ala Gln Lys Ser Ala Leu Ile Arg Arg Tyr Glu

180 185 190Glu Glu Ala Phe Ile Met Cys Leu

195200 (2) SEQ ID NO 602 information

Sequence properties:

(A) length: 167 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 167

(xi) sequence representation: 602 SEQ ID NO 602: Gly Arg Ala Phe Met Met Arg Glu Ile Leu Thr Asn Arg Phe Phe Pro 151015 Ser Leu Phe Lys Lys Arg Leu Asp Phe Ser Asn Arg Val Val Leu Gly

20 25 30Leu Gly Ser Asn Leu Lys Asn Pro Leu Lys Ile Leu Lys Ser Cys Phe

35 40 45Leu Tyr Phe Lys Asn His Ser Lys Ile Gly Lys Ile Phe Ser Ser Pro

5055 60Ile Tyr Ile Asn Pro Pro Phe Gly Tyr Thr Asn Gln Pro Asn Phe Tyr65 70 75 80Asn Ala Thr Ile Ile Leu Lys Thr Ser Leu Gly Leu Arg His Phe Phe

85 90 95Ala Leu Val Phe Tyr Ile Glu Arg Arg Phe Gly Arg Ala Arg Lys Arg

100 105 110Asp Phe Lys Asp Ala Pro Arg Thr Leu Asp Ile Asp Ile Ile Ala Phe

115 120 125Asn Gln Val Ile Leu Arg Gln Asn Asp Leu Thr Leu Pro His Pro Lys

130 135 140Trp Ser Glu Arg Asp Ser Val Leu Val Pro Leu Thr Leu Gln Gln Ile145 150 155 160Leu Phe Lys Arg Glu Glu Trp

165(2) SEQ ID NO 603 information

Sequence properties:

(A) length: 171 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 171

(xi) sequence representation: 603 SEQ ID NO 603: Ile Ile Glu Ile Leu Val Ile Gln Gly Pro Asn Leu Asn Met Leu Gly 151015 His Arg Asp Pro Arg Leu Tyr Gly Met Val Thr Leu Asp Gln Ile His

20 25 30Glu Ile Met Gln Thr Phe Val Lys Gln Gly Asn Leu Asp Val Glu Leu

35 40 45Glu Phe Phe Gln Thr Asn Phe Glu Gly Glu Ile Ile Asp Lys Ile Gln

50 55 60Glu Ser Val Gly Ser Asp Tyr Glu Gly Ile Ile Ile Asn Pro Gly Ala65 70 75 80Phe Ser His Thr Ser Ile Ala Ile Ala Asp Ala Ile Met Leu Ala Gly

85 90 95Lys Pro Val Ile Glu Val His Leu Thr Asn Ile Gln Ala Arg Glu Glu

100 105 110Phe Arg Lys Asn Ser Tyr Thr Gly Ala Ala Cys Gly Gly Val Ile Met

115 120 125Gly Phe Gly Pro Leu Gly Tyr Asn Met Ala Leu Met Ala Met Val Asn

130 135 140Ile Leu Ala Glu Met Lys Ala Phe Gln Glu Ala Gln Lys Asn Asn Pro145 150 155 160Asn Asn Pro Asn Asn Pro Ile Asn Asn Gln Lys

165170 (2) SEQ ID NO:604 information

Sequence properties:

(A) length: 66 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 66

(xi) sequence representation: SEQ ID NO 604: Pro Arg Ile Ile Ala Phe Phe Trp Ile Trp Gly Ser Asn Thr Asn Ala 151015 Ile Ala Leu Ile Gly Leu Ala Arg Leu Phe Leu Asn Pro Lys Asp Phe

20 25 30Val Phs Lys Arg Glu Gln Ser Phe Lys Asp Lys Glu Arg Gln Lys Ile

35 40 45Tyr Asp Ile Val Lys Glu Ala Gln Glu Lys Ala Ile Gln Ala Leu Glu

505560 Arg Gly65(2) SEQ ID NO:605 information

Sequence properties:

(A) length: 70 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 70

(xi) sequence representation: 605 SEQ ID NO: Arg Leu Trp Leu Trp Ala Val Phe Thr His Ser Thr Gly His Gly Ile 15l 015 Asp Leu Asp Ile His Glu Leu Pro Tyr Ile Ser Ser Arg Ser Glu Thr

20 25 30Ile Leu Glu Glu Gly Met Val Phe Ser Val Glu Pro Gly Ile Tyr Ile

35 40 45Pro Gly Phe Phe Gly Val Arg Ile Glu Asp Leu Val Val Ile Lys Asn

505560 Ser Arg Ala Glu Leu Leu 6570 (2) SEQ ID NO:606 information

Sequence properties:

(A) length: 99 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 99

(xi) sequence representation: 606: Tyr Gln Tyr Ile Gln Gln Gly Gly Gly Phe Gly Val Asn Val Gly Arg 151015 Thr Leu Gly Asn Arg Thr His Val Ser Leu G1y Tyr Asn Leu Asn Val SEQ ID NO

20 25 30Thr Lys Leu Leu Gly Phe Ser Ser Pro Leu Tyr Asn Arg Tyr Tyr Ser

35 40 45Ser Val Asn Glu Val Ala Ser Pro Arg Gln Cys Ser Thr Pro Ala Ser

50 55 60Val Ile Ile Asn Arg Leu Ser Gly Gly Arg Thr Pro Leu Val Pro Glu65 70 75 80Ser Cys Ser Ser Pro Gly Ala Ile Thr Ile Phe Thr Arg Asn Lys Arg

859095 Tyr Leu Gly (2) SEQ ID NO 607 information

Sequence properties:

(A) length: 92 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 92

(xi) sequence representation: SEQ ID NO 607: Met Ala Cys Glu Phe Leu Lys Lys Pro Lys Tyr Tyr Lys Phe Ile Glu 151015 Gly Ala Asn Tyr Leu Ser Leu Gly Leu Ser Met Val Val Ala Ile Leu

20 25 30Met Gly Val Ala Ile Gly Tyr Gly Leu Lys Lys Leu Thr His Ile Ser

35 40 45Trp Leu Phe Trp Leu Gly Val Ile Trp Gly Val Leu Ala Ser Phe Leu

50 55 60Asn Val Tyr Lys Ala Tyr Lys Asn Met Gln Lys Asp Tyr Glu Glu Leu65 70 75 80Ala Lys Asp Pro Lys Tyr Thr Gln Asn Lys Thr Lys

8590 (2) SEQ ID NO 608 information

Sequence properties:

(A) length: 89 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 89

(xi) sequence representation: SEQ ID NO 608: Arg Asn Leu Met Lys Thr Thr Glu Asn Thr Asp Glu Thr His Leu Arg 1510 l5Glu Thr Lys Asn Lys Leu Gly Arg Lys Pro Lys Ala Asp Ala Asn Lys

20 25 30Lys Thr Arg Ala Val Ser Leu Tyr Phe Ser Asp Glu Gln Tyr Gln Lys

35 40 45Leu Glu Lys Met Ala Asn Glu Glu Glu Glu Ser Val Gly Ser Tyr Ile

50 55 60Lys Arg Tyr Ile Leu Lys Ala Leu Arg Lys Ile Glu Gln Gly Gly Gly65 70 75 80Phe Ile Ala Phe Asn Leu Phe Leu Ile

85(2) SEQ ID NO 609 information

Sequence properties:

(A) length: 103 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: msc _ feature

(B) Position: 1 … 103

(xi) sequence representation: 609 SEQ ID NO: Ile Leu Lys Gly Gly Phe Leu Gly Phe Phe Ile Val Ala Leu Ser Ser 151015 Tyr Tyr Gly Val Lys Lys Arg Leu Asp Leu Arg Lys Gln Asp Ser Lys

20 25 30Glu Lys Glu Glu Lys Gln Lys Phe Gln Lys Phe Ala Leu Gly Leu Glu

35 40 45Met Ser Phe Asn Val Trp Arg Leu Gly Gly Tyr Gly Val Leu Leu Gly

50 55 60Ile Leu Gly Val Leu Leu Phe Leu His Leu Phe Asn Gly Leu Pro Phe65 70 75 80Leu Ile Gly Val Phe Val Ser Ser Leu Ser Ser Ala Leu Leu Arg Phe

85 90 95Leu Asn Asn Asn Gly Lys Phe

100(2) SEQ ID NO 610 information

Sequence properties:

(A) length: 257 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 257

(xi) sequence representation: SEQ ID NO 610: Ala Leu Thr Pro Asn Pro Met Lys Leu Pro Val Val Glu Ser Phe Phe 151015 Ser Leu Gln Gly Glu Gly Lys Arg Ile Gly Lys Pro Ser Leu Phe Leu

20 25 30Arg Leu Gly Gly Cys Asn Leu Ser Cys Lys Gly Phe Asn Cys Lys Thr

35 40 45Leu Phe Asn Asp Glu Ile Leu Thr Gly Cys Asp Ser Leu Tyr Ala Val

50 55 60His Pro Lys Phe Lys Thr Ser Trp Asp Tyr Tyr Asn Glu Pro Lys Pro65 70 75 80Leu Ile Glu Arg Leu Val Asn Leu Ala Pro Asn Tyr Lys Asp Phe Asp

85 90 95Phe Ile Leu Thr Gly Gly Glu Pro Ser Leu Tyr Phe Asn Asn Pro Ile

100 105 110Leu Leu Ser Val Leu Glu His Phe Tyr His Lys Lys Ile Pro Leu Phe

115 120 125Val Glu Ser Asn Gly Ser Ile Phe Phe Glu Phe Ser Pro Ile Leu Lys

130 135 140Glu Leu His Phe Thr Leu Ser Val Lys Leu Ser Phe Ser Leu Glu Gln145 150 155 160Glu Ser Lys Arg Ile Asn Leu Lys Ala Leu Gln Asn Ile Leu Asn Asn

165 170 175Ala Lys Ser Val His Phe Lys Phe Val Leu Glu Ser Gln Asn Ala Ala

180 185 190His Ser Ile Ala Glu Ile Gln Ser Leu Leu Lys Gln Leu Ser Leu Lys

195 200 205Asn Asn Glu Ile Phe Leu Met Pro Leu Gly Thr Thr Asn Asn Glu Leu

210 215 220Asp Lys Asn Leu Lys Thr Leu Ala Pro Leu Ala Ile Glu His Gly Phe225 230 235 240Arg Leu Ser Asp Arg Leu His Ile Arg Leu Trp Asp Asn Lys Lys Gly

245250255 Phe (2) SEQ ID NO 61l information

Sequence properties:

(A) length: 386 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 386

(xi) sequence representation: 611: Phe Lys Asp Gln Gly Met Asn Leu Asn Phe Met Pro Leu Leu His Ala 151015 Tyr Asn His Val Ser Ile Asp Phe His Phe Asn Ser Ser Ala Arg Asp SEQ ID NO

20 25 30Phe Cys Val His Glu Val Pro Leu Tyr Glu Phe Ser Asn Thr Gly Glu

35 40 45His Ala Val Ile Gln Val Arg Lys Ser Gly Leu Ser Thr Leu Glu Met

50 55 60Leu Gln Ile Phe Ser Gln Ile Leu Gly Val Lys Ile Ala Glu Leu Gly65 70 75 80Tyr Ala Gly Leu Lys Asp Lys Asn Ala Leu Thr Thr Gln Phe Ile Ser

85 90 95Leu Pro Lys Lys Tyr Ala Pro Leu Leu Glu Lys Asn Thr Ser Asn Phe

100 105 110Gln Glu Arg Asn Leu Lys Ile Leu Ser Leu Asn Tyr His His Asn Lys

115 120 125Ile Lys Leu Gly His Leu Lys Gly Asn Arg Phe Phe Met Arg Phe Lys

130 135 140Lys Met Thr Pro Leu Asn Ala Gln Lys Thr Glu Gln Val Leu Glu Gln145 150 155 160Ile Ala Gln Phe Gly Met Pro Asn Tyr Phe Gly Ser Gln Arg Phe Gly

165 170 175Lys Phe Asn Asp Asn His Lys Glu Gly Leu Lys Ile Leu Gln Asn Glu

180 185 190Thr Lys Phe Ala His Gln Lys Leu Asn Ala Phe Leu Ile Ser Ser Tyr

195 200 205Gln Ser Tyr Leu Phe Asn Ser Leu Leu Ser Lys Arg Leu Glu Ile Ser

210 215 220Lys Ile Ile Ser Ala Phe Ser Val Lys Glu Ser Leu Glu Phe Phe Lys225 230 235 240Gln Lys Asn Leu Ser Val His Ser Asn Ala Leu Lys Ala Leu Lys Asn

245 250 255Gln Ala His Pro Phe Lys Ile Leu Glu Gly Asp Val Met Arg His Tyr

260 265 270Pro Tyr Gly Lys Phe Phe Asp Ala Leu Glu Leu Glu Lys Glu Ser Glu

275 280 285Arg Phe Leu Asn Lys Glu Ala Val Pro Thr Gly Leu Leu Asp Gly Lys

290 295 300Lys Ala Leu Tyr Ala Lys Asn Leu Ser Leu Glu Ile Glu Lys Gly Phe305 310 315 320Gln His Asn Leu Leu Ser Gly His Ala Lys Thr Leu Gly Ser Arg Arg

325 330 335Phe Phs Trp Val Phe Val Glu Asn Ile Thr Ser Gln Tyr Ile Lys Glu

340 345 350Lys Ala Gln Phe Glu Leu Glu Phe Tyr Leu Pro Lys Gly Ser Tyr Ala

355 360 365Ser Ala Leu Leu Lys Glu Ile Lys His Glu Lys Gly Glu Asn Asn Asp

370375380 Glu Phe385(2) SEQ ID NO:612 information

Sequence properties:

(A) length: 63 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 63

(xi) sequence representation: SEQ ID NO 612: Lys Ile Lys Gly Lys Glu Met Lys Phe Leu Asn Gly Leu Ala Gly Asn 151015 Leu Leu Ile Val Val Ile Leu Leu Cys Val Val Val Phe Phe Ala Leu

20 25 30Lys Ala Ile His Ile Gln Lys Glu Gln Ala Thr Asn Tyr Tyr Arg Tyr

35 40 45Lys Asp Ile Asn Ala Leu Glu Ala Lys Asn Thr Gln Asn His Ala

505560 (2) SEQ ID NO:613 message

Sequence properties:

(A) length: 100 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 100

(xi) sequence representation: SEQ ID NO 613: Met Leu Glu Ile Glu Leu Lys Lys Lys Phe Thr Lys Asp Leu Lys Lys 151015 His Ile Leu Asn Gln Lys Ile Glu Leu Glu Val Phe Asp Leu Val Val

20 25 30Glu Asn Leu Arg Asn Gln Ile Pro Leu Asp Lys Arg Phe Lys Asp His

35 40 45Ala Leu Ser Gly Thr Tyr Lys Gly Cys Arg Glu Arg His Ile Lys Pro

50 55 60Asp Val Leu Leu Val Tyr Arg Val Lys Gly Asn Val Leu Thr Leu Val65 70 75 80Arg Leu Gly Ser His Ser Glu Leu Phe Cys Lys Pro Pro Thr Pro Leu

85 90 95Ile Thr Leu Lys

100(2) SEQ ID NO:614 information

Sequence properties:

(A) length: 646 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … … 646

(xi) sequence representation: 614: Ser Asn Tyr Asn Asn Leu Asn Thr Leu Val Ser Leu Ser Ser Asp Pro 15l 015 Ser Ala Val Asn Asp Ala Arg Asp Asn Leu Gly Ser Ser Ala Arg Asn SEQ ID NO

20 25 30Leu Leu Asp Val Lys Ala Asn Ser Pro Ala Tyr Gln Ala Val Leu Leu

35 40 45Ala Leu Asn Ala Ala Val Gly Leu Trp Gln Val Thr Ser Tyr Ala Phe

50 55 60Thr Ala Cys Gly Pro Gly Ser Asn Glu Asn Ala Asn Gly Gly Ile Gln65 70 75 80Thr Phe Asn Asn Val Pro Gly Gln Asn Thr Thr Thr Ile Thr Cys Asn

85 90 95Ser Tyr Tyr Glu Pro Gly His Gly Gly Pro Ile Ser Thr Glu Asn Tyr

100 105 110Ala Ile Ile Asn Lys Ala Tyr Gln Ile Ile Gln Lys Ala Leu Thr Ala

115 120 125Asn Gly Glu Gly Ile Pro Val Leu Ser Asn Thr Thr Thr Lys Leu Asp

130 135 140Phe Thr Ile Asn Gly Asp Lys Arg Thr Gly Gly Glu Pro Asn Lys Lys145 150 155 160Leu Val Tyr Pro Trp Ser His Gly Lys Ala Ile Ser Thr Ser Trp Ash

165 170 175Ala Thr Ile Thr Val Pro Thr Thr Glu Asn Ile Asn Thr Thr Asn Ser

180 185 190Ala Gln Glu Leu Leu Lys Gln Ala Ser Ile Ile Ile Thr Thr Leu Asn195 200 205Ser Ala Cys Pro Asn Phe Gln Asn Gly Gly Ser Gly Tyr Trp Ala Gly

210 215 220Ile Ser Gly Asn Gly Thr Met Cys Gly Met Phe Lys Asn Glu Ile Ser225 230 235 240Ala Ile Gln Gly Met Ile Ala Asn Ala Gln Glu Ala Val Ala Gln Ala

245 250 255Lys Ile Val Ser Glu Asn Thr Gln Asn Gln Asn Ser Leu Asp Ala Gly

260 265 270Lys Pro Phe Asn Pro Tyr Thr Asp Ala Ser Phe Ala Glu Ser Met Leu

275 280 285Lys Asn Ala Gln Ala Gln Ala Glu Ile Leu Asn Gln Ala Glu Gln Val

290 295 300Val Lys Asn Phe Glu Lys Ile Pro Thr Ala Phe Val Asn Asp Ser Leu305 310 315 320Gly Val Cys Tyr Glu Val Gln Gly Gly Glu Arg Arg Gly Thr Asn Pro

325 330 335Gly Gln Thr Thr Ser Asn Thr Trp Gly Ala Gly Cys Ala Tyr Val Gly

340 345 350Gln Thr Ile Thr Asn Leu Lys Asn Ser Ile Ala His Phe Gly Thr Gln

355 360 365Glu Gln Gln Ile Gln Gln Ala Glu Asn Ile Ala Asp Thr Leu Val Asn

370 375 380Phe Lys Ser Arg Tyr Ser Glu Leu Gly Asn Thr Tyr Asn Ser Ile Thr385 390 395 400Thr Ala Leu Ser Asn Ile Pro Asn Ala Gln Ser Leu Gln Asn Ala Val

405 410 415Ser Lys Lys Asn Asn Pro Tyr Ser Pro Gln Gly Ile Asp Thr Asn Tyr

420 425 430Tyr Leu Asn Gln Asn Ser Tyr Asn Gln Ile Gln Thr Ile Asn Gln Glu

435 440 445Leu Gly Arg Asn Pro Phe Arg Lys Val Gly Ile Val Ser Ser Gln Thr

450 455 460Asn Asn Gly Ala Met Asn Gly Ile Gly Ile Gln Val Gly Tyr Lys Gln465 470 475 480Phe Phe Gly Gln Lys Arg Lys Trp Gly Ala Arg Tyr Tyr Gly Phe Phe

485 490 495Asp Tyr Asn His Ala Phe Ile Lys Ser Ser Phe Phe Asn Ser Ala Ser

500 505 510Asp Val Trp Thr Tyr Gly Phe Gly Ala Asp Ala Leu Tyr Asn Phe Ile

515 520 525Asn Asp Lys Ala Thr Asn Phe Leu Gly Lys Asn Asn Lys Leu Ser Val

530 535 540Gly Leu Phe Gly Gly Ile Ala Leu Ala Gly Thr Ser Trp Leu Asn Ser545 550 555 560Glu Tyr Val Asn Leu Ala Thr Met Asn Asn Val Tyr Asn Ala Lys Met

565 570 575Asn Val Ala Asn Phe Gln Phe Leu Phe Asn Met Gly Val Arg Met Asn

580 585 590Leu Ala Arg Pro Lys Lys Lys Asp Ser Asp His Ala Ala Gln His Gly

595 600 605Ile Glu Leu Gly Leu Lys Ile Pro Thr Ile Asn Thr Asn Tyr Tyr Ser

610 615 620Phe Met Gly Ala Glu Leu Lys Tyr Arg Arg Leu Tyr Ser Val Tyr Leu625 630 635 640Asn Tyr Val Phe Ala Tyr

645(2) SEQ ID NO 615 information

Sequence properties:

(A) length: 93 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 93

(xi) sequence representation: 615: Asp Leu Lys Met Leu Thr Ile Glu Thr Ser Lys Lys Phe Asp Lys Asp 151015 Leu Lys Ile Leu Val Lys Asn Gly Phe Asp Leu Lys Leu Leu Tyr Lys SEQ ID NO

20 25 30Val Val Gly Asn Leu Ala Thr Glu Gln Pro Leu Glu Pro Lys Tyr Lys

35 40 45Asp His Pro Leu Lys Gly Ala Leu Lys Asp Phe Arg Glu Cys His Leu

50 55 60Lys Pro Asp Leu Leu Leu Val Tyr Gln Ile Lys Lys Gln Glu Asn Thr65 70 75 80Leu Phe Leu Val Arg Leu Gly Ser His Ser Glu Leu Phe

8590 (2) SEQID NO:616 message

Sequence properties;

(A) length: 81 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 81

(xi) sequence representation: 616: Arg Ala Trp Arg Met Lys Ser Met Arg Phe Ser Tyr Ile Glu Pro Arg 151015 Ala Lys Tyr Leu Ile Ser Lys Leu Ser Lys Ile Trp Val Phe Tyr Ile SEQ ID NO

20 25 30Phe Leu Ser Phe Val Leu Ile Gly Gly Leu Val Trp Phe Met His Asn

35 40 45Ala Ile Lys Arg Ala Gln Asp Asn Ala Ser Ser Leu Thr Ile Gln Glu

505560 Glu Leu Tyr Arg Cys Tyr Ile Thr Arg Leu Ser Val Lys Met Ile Ile 65707580 Leu (2) SEQ ID NO 617 information

Sequence properties:

(A) length: 149 amino acid sequence

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 149

(xi) sequence representation: 617: Val Lys Phe Pro Tyr Leu Leu Asn Ile Arg Ile Met Leu Tyr Leu Arg 151015 Lys Glu Asn Gly Val Arg Thr Leu Ile Ser Leu Gly Ile Leu Leu Ser SEQ ID NO

20 25 30Val Leu Asn Gly Asp Asp Leu Arg Leu Tyr Ser Lys Pro Leu Val Tyr

35 40 45Ser Ala Gly Ser Gly Ile Ile Gly Ile Asp Ile Asp Lys Arg Thr Phe

50 55 60Tyr Lys Arg Ala Phe Ala Phe Thr Met Lys Ser Leu Phe Gly Glu Asn65 70 75 80Leu Leu Leu Phe Val Lys Leu Lys His Ser Ala Leu Met Ser Lys His

85 90 95Met Lys Gly Pro Leu Glu Asn Arg His His His Ser Phe Ala Lys Asn

100 105 110Tyr Glu Lys Ala Val Asn Gly Cys Gln Lys Tyr Val His Ile Lys Leu

115 120 125Pro Glu Gly Pro Pro Ser Asn Phe Gln Ser Gly Ser Tyr Met Ala Thr

130135140 Met Val Met Arg Phe145(2) SEQ ID NO 618 information

Sequence properties:

(A) length: 159 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 159

(xi) sequence representation: 618 SEQ ID NO: Val Ile Thr Asn Gln Gln Asn Glu Val Lys Thr Phe Thr Pro Ile Glu 151015 Thr Lys Lys Ile Thr Ser Lys Glu Gln Ala Phe Leu Thr Leu Ser Ala

20 25 30Leu Met Asp Ala Val Glu Asn Gly Thr Gly Ser Leu Ala Arg Ile Lys

35 40 45Gly Leu Glu Ile Ala Gly Lys Thr Gly Thr Ser Asn Asn Asn Ile Asp

50 55 60Ala Trp Phe Ile Gly Phe Thr Pro Thr Leu Gln Ser Val Ile Trp Phe65 70 75 80Gly Arg Asp Asp Asn Thr Pro Ile Gly Lys Gly Ala Thr Gly Gly Val

85 90 95Val Ser Ala Pro Val Tyr Ser Tyr Phe Met Arg Asn Ile Leu Ala Ile

100 105 110Glu Pro Ser Leu Lys Arg Lys Phe Asp Val Pro Lys Gly Leu Arg Lys

115 120 125Glu Ile Val Asp Lys Ile Pro Tyr Tyr Ser Ser Pro Asn Ser Ile Thr

130 l 35140 Pro Thr Pro Lys Lys Thr Asp Asp Ser Glu Glu Arg Leu Leu Phe 145150155 (2) SEQ ID NO:619 information

Sequence properties:

(A) length: 80 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 80

(xi) sequence representation: SEQ ID NO 619: Leu Leu Leu Asn Leu Lys Ile Tyr Val Thr Leu Cys Lys Ile Gln Gly 151015 Asp Ser Val Leu Glu Lys Ser Phe Leu Lys Ser Lys Gln Leu Val Leu

20 25 30Cys Gly Leu Gly Val Phe Met Leu Gln Ala Leu His Phe Ala Gln Thr

35 40 45Leu His Lys Glu Ile Leu Phe Tyr Lys Met Cys Leu Ile Gly Cys Cys

505560 Lys Ile Ala Ala Ser Ile Ser Arg Lys Gly Trp Ile Ala Arg Thr Leu 65707580 (2) SEQ ID NO:620 information

Sequence properties:

(A) length: 344 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 344

(xi) sequence representation: SEQ ID NO 620: Val Lys Cys Gly Lys Lys Gly Ile Leu Val Ser Thr Arg Lys Ala Met 151015 Phe Leu Cys Lys Ile Pro Leu Ser Leu Thr Leu Met Glu Ala Arg Ser

20 25 30Val Leu Thr Gln Glu Ile Arg Ser Phe Leu Pro Glu Thr Thr Thr Ser

35 40 45Leu Ser Leu Thr Ile Leu Glu Arg Ser Ile Cys Cys Leu Ile Lys Phe

50 55 60Leu Thr Leu Thr Ser Pro Cys Leu Thr Gln Gln Arg Pro Lys Ile Asn

65 70 75 80Ala Thr Asn Asn Asn Val Ser Val Ser Gln Gly Asn Leu Phe Ile Asn

85 90 95Ala Ser Cys Val Gln Gln Ser Asp Pro Thr Thr Ala Ser Ala Thr Asn

100 105 110Pro Cys Thr Thr Ala Gln Asn Asn Ala Ser Ser Ser Asn Ala Ser Asn

115 120 125Asn Ala Pro Ile Ala Leu Asn Asn Asn Asp Glu Ser Leu Val Val Thr

130 135 140Ala Asn Gly Phe Asn Phe Ser Gly Asn Ile Tyr Ala Asn Gly Val Val145 150 155 160Asp Phe Ser Lys Ile Lys Gly Ser Ala Asn Val Lys Asn Leu Tyr Leu

165 170 175Tyr Asn Asn Ala Gln Phe Gln Ala Asn Asn Leu Thr Ile Ser Asn Gln

180 185 190Ala Val Leu Glu Lys Asn Ala Ser Phe Val Thr Asn Asn Leu Asn Ile

195 200 205Gln Gly Ala Phe Asn Asn Asn Ala Thr Gln Lys Ile Glu Val Leu Gln

210 215 220Asn Leu Val Ile Ala Ser Asn Ala Ser Leu Ser Thr Gly Ile Tyr Gly225 230 235 240Leu Glu Val Gly Gly Ala Leu Asn Asn Leu Gly Ala Ile His Phe Asn

245 250 255Leu Glu Asn Ser Gln Thr Pro Val Asn Pro Leu Ile Gln Val Gly Gly

260 265 270Ile Ile Asn Leu Asn Thr Thr Gln Thr Pro Phe Met Asn Val Ser Val

275 280 285Ala Asn Gly Gly Thr Tyr Thr Leu Leu Lys Ser Ser Arg Tyr Ile Asp

290 295 300Tyr Asn Ile Asn Pro Asn Ser Leu Gln Ser Tyr Leu Lys Leu Tyr Thr305 310 315 320Leu Ile Asn Ile Asn Gly Asn His Ile Glu Glu Lys Asn Gly Val Leu

325 330 335Thr Tyr Leu Gly Gln Arg Val Leu

340(2) SEQ ID NO 621 information

Sequence properties:

(A) length: 266 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 266

(xi) sequence representation: 621: Leu Leu Ala Arg Thr Ile Leu Asp Phe Arg Gly Ser Leu Ser Asn Leu 151015 Asn Asn Thr Tyr Asn Ser Ile Thr Thr Thr Ala Ser Asn Thr Pro Asn SEQ ID NO

20 25 30Ser Pro Phe Leu Lys Asn Leu Ile Ser Gln Ser Thr Asn Pro Asn Asn

35 40 45Pro Gly Gly Leu Gln Ala Val Tyr Gln Val Asn Gln Ser Ala Tyr Ser

50 55 60Gln Leu Leu Ser Ala Thr Gln Glu Leu Gly His Asn Pro Phe Arg Arg6570 75 80Val Gly Leu Ile Ser Ser Gln Thr Asn Asn Gly Ala Met Asn Gly Ile

85 90 95Gly Val Gln Val Gly Tyr Lys Gln Phe Phe Gly Glu Lys Arg Arg Trp

100 105 110Gly Leu Arg Tyr Tyr Gly Phe Phe Asp Tyr Asn His Ala Tyr Ile Lys

115 120 125Ser Ser Phe Phe Asn Ser Ala Ser Asp Val Phe Thr Tyr Gly Val Gly

130 135 140Thr Asp Val Leu Tyr Asn Phe Ile Asn Asp Lys Thr Thr Lys Asn Ser145 150 155 160Lys Ile Ser Phe Gly Val Phe Gly Gly Ile Ala Leu Ala Gly Thr Ser

165 170 175Trp Leu Asn Ser Gln Tyr Val Asn Leu Ala Thr Phe Asn Asn Phe Tyr

180 l85 190Ser Ala Lys Met Asn Val Ala Asn Phe Gln Phe Leu Phe Asn Leu Gly

195 200 205Leu Arg Met Asn Leu Ala Lys Asn Lys Lys Lys Asp Ser Asp His Ala

210 215 220Ala Gln His Gly Val Glu Leu Gly Val Lys Ile Pro Thr Ile Asn Thr225 230 235 240Asn Tyr Tyr Ser Phe Leu Gly Thr Lys Leu Glu Tyr Arg Arg Leu Tyr

245 250 255Ser Val Tyr Leu Asn Tyr Val Phe Ala Tyr

260265 (2) SEQ ID NO 622 message

Sequence properties:

(A) length: 95 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 95

(xi) sequence representation: 622: Arg Asn Val Glu Ala Arg Tyr Tyr Tyr Gly Asp Thr Ser Tyr Phe Tyr 151015 Leu His Ala Gly Val Leu Gln Glu Phe Ala His Phe Gly Ser Asn Asp SEQ ID NO

20 25 30Val Ala Ser Leu Asn Thr Phe Lys Ile Asn Ala Ala Arg Ser Pro Leu

35 40 45Ser Thr Tyr Ala Arg Ala Met Met Gly Gly Glu Leu Gln Leu Ala Lys

50 55 60Glu Val Phe Leu Asn Leu Gly Val Val Tyr Leu His Asn Leu Ile Ser65 70 75 80Asn Ala Ser His Phe Ala Ser Asn Leu Gly Met Arg Tyr Ser Phe

859095 (2) SEQ ID NO 623 information

Sequence properties:

(A) length: 155 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1 … 155

(xi) sequence representation: 623: Arg Leu Pro Lys Lys Glu Asp Tyr Ala Lys Ala Met Val Phe Ser Phe 151015 Lys Met Glu Ala Ile Lys Glu Ser Gln Ile Val Leu Leu Ile Thr Ser SEQ ID NO

20 25 30Ala Phe Glu Gly Gln Phe Glu Lys Thr His Lys Glu Glu Lys Glu Glu

35 40 45Thr Thr Lys Ser Ala Thr Glu Glu Thr Lys Thr His Asp Ala Ser Leu

50 55 60Glu Asn Ile Glu Ile Arg Asn Ile Ser Met Leu Leu Asp Val Lys Leu65 70 75 80Asn Val Lys Val Arg Ile Gly Gln Lys Lys Met Ile Leu Lys Asp Val

85 90 95Val Ser Met Asp Ile Gly Ser Val Val Glu Leu Asp Gln Leu Val Asn

100 105 110Asp Pro Leu Glu Ile Leu Val Asp Asp Lys Val Ile Ala Lys Gly Glu

115 120 125Val Val Ile Val Asp Gly Asn Phe Gly Ile Gln Ile Thr Asp Ile Gly

130135140 Thr Lys Lys Glu Arg Leu Glu Gln Leu Lys Asn 145150155 (2) SEQ ID NO:624 information

Sequence properties:

(A) length: 211 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...211

(xi) sequence representation: 624 SEQ ID NO, Lys Pro Thr Asn Val Trp Ala Asn Ala Ile Gly Gly Ala Ser Leu Asn 151015 Ser Gly Ser Asn Ala Ser Leu Tyr Gly Thr Ser Ala Gly Val Asp Ala

20 25 30Phe Leu Asn Gly Asn Val Glu Ala Ile Val Gly Gly Phe Gly Ser Tyr35 40 45Gly Tyr Ser Ser Phe Ser Asn Gln Ala Asn Ser Leu Asn Ser Gly Ala

50 55 60Asn Asn Ala Asn Phe Gly Val Tyr Ser Arg Phe Phe Ala Ash His Pro65 70 75 80Glu Phe Asp Phe Glu Ala Gln Gly Ala Leu Gly Ser Asp Gln Ser Ser

85 90 95Leu Asn Phe Lys Ser Thr Leu Leu Gln Asp Leu Asn Gln Ser Tyr Asn

100 105 110Tyr Leu Ala Tyr Ser Ala Thr Ala Arg Ala Ser Tyr Gly Tyr Asp Phe

115 120 125Ala Phe Phe Arg Asn Ala Leu Val Leu Lys Pro Ser Val Gly Val Ser

130 135 140Tyr Asn His Leu Gly Ser Thr Asn Phe Lys Ser Asn Ser Gln Ser Gln145 150 155 160Val Ala Leu Lys Asn Gly Ala Ser Ser Gln His Leu Phe Asn Ala Asn

165 170 175Ala Thr Trp Lys Arg Val Ile Ile Met Gly Thr Leu His Thr Phe Ile

180 185 190Cys Met Arg Glu Phe Tyr Lys Ser Ser Leu Thr Leu Asp Arg Met Met

195 200 205Trp Arg Leu

210(2) SEQ ID NO 625 information

Sequence properties:

(A) length: 343 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...343

(xi) sequence representation: 625: His Ala Arg Glu Phe Cys Gln Val Val Met Phe His Lys Ala Leu Ile 151015 Thr Phe Ile Val Leu Trp Phe Phe Leu Asn Gly Leu Gly Ala Tyr Asp SEQ ID NO

20 25 30Phe Lys His Cys Gln Ala Phe Phe Lys Lys Ala Ser Leu Gln Lys Gly

35 40 45Gly Val Ala Leu Lys Glu Leu Pro Lys Gly Val Tyr Leu Tyr Tyr Ser

50 55 60Lys Thr Tyr Pro Lys His Ala Lys Val Ile Lys Ser Asp Pro Phe Ile65 70 75 80Gly Leu Tyr Leu Leu Gln Ser Ala Pro Ser Glu Tyr Val Tyr Thr Leu

85 90 95Arg Asp Leu Asp Lys Asp Ala Leu Ile Arg Pro Met Ala Ser Ile Gly

100 105 110Ala Asn Gln Ala Thr Glu Ala Arg Leu Leu Val Gly Gln Lys Gly Tyr

115 120 125Asp Arg Tyr Ala Gln Ile Ser Gln Lys Thr Gln Lys Asn Gly Val Ile

130 135 140Ser Asn lle Cys Tyr Gln Met Leu Gly Leu Gly Val GlyGly Asn Gly145 150 155 160Phe Ile Glu Thr Lys Phe Ile Lys Arg Phe Leu Asn Gln Gln Glu Pro

165 170 175Tyr Tyr Gly Asp Ile Gly Val Arg Leu Glu Glu Arg His Lys Arg Leu

180 185 190Val Val Ala Gln Phe Asp Pro Phe Phe Pro Lys Asn Pro Phe Leu Lys

195 200 205Asn Asp Glu Ile Leu Ala Ile Asn Asp Tyr Lys Ile His Ser Leu Ala

210 215 220Glu Phe Glu Trp Val Val Ser Asn Leu Ser Tyr Gln Ser Leu Ala Lys225 230 235 240Val Lys Ile Lys Arg Asn His Gln Ile Lys Glu Val Thr Leu Lys Val

245 250 255Asn Lys Arg Tyr Gly Gly Phe Leu Leu Lys ASp Thr Phe Leu Glu Arg

260 265 270Tyr Gly Ile Ala Leu Asp Glu Arg Phe Ile Ile Thr Lys Ile Gly Ala

275 280 285His Leu Pro Lys Gly Leu Asp Phe Leu Lys Leu Gly Asp Arg Ile Leu

290 295 300Trp Val Asn His Arg Ser Val Ser Phe Asn Pro Lys Ala Leu Arg Glu305 310 315 320Ala Leu Ser Thr Pro Lys Ile Glu Leu Leu Val Trp Arg Gln Gly Phe

325 330 335Glu Phe Tyr Ile Lys Val Arg

340(2) SEQ ID NO 626 information

Sequence properties:

(A) length: 165 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...165

(xi) sequence representation: SEQ ID NO:626: Ile Lys Ile Asn Met Val Glu Cys Gln Asn Leu Leu Ser Ser Cys Gly 151015 Lys Asn Leu Asp Asn Lys Glu Leu Gly Met Arg Arg Ser Leu Ala Phe

20 25 30Cys Leu Leu Ala Leu Leu Gly Leu Gln Val Leu Gly Ala Arg Asp Phe

35 40 45Ser Gln Leu Lys Asn Glu Glu Leu Leu Lys Leu Ala Gly Thr Leu Pro

50 55 60Ser Asn Glu Ala Ile Asp Tyr Arg Met Glu Val Ser Lys Arg Leu Ile65 70 75 80Ala Leu Ser Ala Glu Asp Ala Lys Asn Phe Arg Ala Asn Phe Ser Arg

85 90 95Ile Ala Arg Lys Asn Leu Ser Lys Met Ser Glu Glu Asp Phe Lys Lys

100 105 110Met Arg Glu Glu Val Arg Lys Glu Leu Glu Glu Lys Thr Lys Gly Leu

115 120 125Ser Ala Glu Glu Ile Lys Ala Lys Gly Leu Asn Val Ser Val Cys Ser

130 135 140Gly Asp Thr Arg Lys Val Trp Cys Arg Ala Val Lys Lys Lys Asp Glu145 150 155 160His Cys Ser Pro Lys

165(2) SEQ ID NO 627 information

Sequence properties:

(A) length: 157 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...157

(xi) sequence representation: SEQ ID NO 627: Phe Lys Arg Lys Asn Met Lys Lys Ala Leu Lys Ile Leu Ser Val Gly 151015 Ala Leu Leu Phe Val Ala Leu Asn Ala Lys Asp Phe Ser Lys Thr Ser

20 25 30Asp Glu Asp Leu Ala Lys Met Ala Gly Val Val Ala Pro Gln Asp Ile

35 40 45Val Asp Tyr Thr Lys Glu Leu Lys Lys Arg Met Glu Lys Met Pro Glu

50 55 60Asp Lys Arg Lys Ala Phe His Lys Gln Leu His Glu Tyr Ala Thr Lys65 70 75 80Asn Thr Asp Lys Met Thr Val Ala Asp Phe Glu Ala Arg Gln Lys Ala

85 90 95Ile Lys Glu Ala Leu Lys Lys Gly Asn Met Glu Asp Met Asp Asp Asp

100 105 110Phe Gly Leu Arg Ser Cys Lys His Gly Lys Lys His Lys His Asp Lys

115 120 125His Gly Lys Lys His Gly Lys Lys His Asp Lys Asp His Asp Asp Lys

130135140 Asp His Asp His His Asp Glu Asp His Ser Asp Lys His 145150155 (2) SEQ ID NO:628 information

Sequence properties:

(A) length: 677 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...677

(xi) sequence representation: 628: Ile Gln Arg Tyr Trp Asn Gly Ala Leu Met Lys Asn Gln Mis Lys Asn 151015 Pro Leu Thr Lys Ala Leu Met Lys Thr Tyr Pro Tyr Asn His Phe Leu SEQ ID NO

20 25 30Phe Phe Cys Phe Ile Leu Gly Ala Phe Leu Leu Gly Leu Leu Ser Pro

35 40 45Ala Tyr Ala Leu Ser Ile Ile Thr Thr Lys Glu Ile Asp Ala Asn Leu

50 55 60Leu Asn Gly Ala Ile Glu Ser Arg Val val Leu Gly Lys Arg Val Phe65 70 75 80Lys Val Glu Ala His Gly Phe Tyr Phe Arg Asn Asn Ala Thr Asn Ser

85 90 95Ile Asp Ile Glu Ile Thr Ser Leu Leu Arg Asp Asn Gln Ser Phe Pro

100 105 110Leu Thr Ser Ser Ala Lys Thr Ser Leu Lys Ile Pro Pro Asn Ala Lys

115 120 125Ile Lys Lys Ser Thr Ile Leu Val Leu Lys Gly Glu Asn Ala Glu Glu

130 135140Val Ala Lys Ile Leu Gly Val Ser Lys Glu Glu Tyr Gln Lys Leu Glu145 150 155 160Asn Ile Ala Gln Thr Lys Ala Ala Asn Asp Pro Met Tyr Ala Asn Thr

165 170 175Pro Phe Ser Asn Gly Ser Asp Ser Ser Phe Tyr Asp Asn Asn Pro Asn

180 185 190Ser Pro Ser Asn Asn Ala Ile Asn Gly Lys Asp Gly Ala Asn Gly Ser

195 200 205Asn Gly Tyr Gly Ala Asn Gly Asn Asp Gly Val Asn Gly Ile Ser Gly

210 215 220Ser Asn Gly Ala Asn Gly Ser His Ser Asn Asn Asn Ala Ile Gly Ser225 230 235 240Gly Ile Asp Thr Asp Gly Val Leu Gly Val Asp Gly Val Asn Gly Ser

245 250 255Ser Ser Ser Ser Gly Gly Ser Val Gly Gly Tyr Glu Asn Asn Phe Thr

260 265 270Asn His Gly Ser Thr Asn Asn Asn Thr Gly Gly Tyr Asp Asn Phe Asn

275 280 285Asn Gly Ser Ser Ser Gly Gly Ser Leu Gly Asn Gly Gly Leu Phe Pro

290 295 300Ile Pro Phe Gly Asn Gly Asp Thr Asn Asn Ser Asn Asn Ser Thr Asn305 310 315 320Thr Thr Ser Pro Thr Asn Gly Ser Ser Ser ASn Asn Ala Thr Asn Pro

325 330 335Ser Ser Gln Glu Asn Asn Tyr Ser Ser Gln Tyr Cys Lys Val Pro Glu

340 345 350Leu Ser Pro Asn Asn Thr Met Lys Leu Asp Val Ile Ala Lys Asp Gly

355 360365Ser Cys Ile Ser Met Asn Ala Leu Arg Asp Asp Thr Lys Cys Ala Tyr

370 375 380Arg Tyr Asp Phe Glu Ala Gly Lys Ala Ile Lys Gln Thr Gln Tyr Tyr385 390 395 400Tyr Val Asp Arg Glu Asn Lys Thr Gln Asn Ile Gly Gly Cys Val Asp

405 410 415Leu Gln Gly Ala Gln Tyr Ala Met Gln Leu Tyr Lys Asp Asp Ser Lys

420 425 430Cys Ala Leu Gln Thr Thr Ser Asp Lys Gly Tyr Gly Met Gly Lys Thr

435 440 445Gln Thr Phe Gln Thr Glu Ile Val Phe Arg Gly Met Asp Asn Leu Ile

450 455 460His Val Ala Val Pro Cys Ser Asp Tyr Ala Arg Val Gln Asp Arg Ile465 470 475 480Val Arg Tyr Glu Lys Asn Asp Lys Thr Gln Thr Leu Thr Pro Ile Val

485 490 495Asp Gln Tyr Tyr Asn Asp Pro Asn Asn Pro Asn Lys Gln Glu Ile Leu

500 505 510Asn Arg Gly Ile Ala Thr Gln Leu Ser Ser Gln Tyr Gln Glu Phe Ala

515 520 525Cys Gly Gln Trp Glu Tyr Asn Asp Ala Lys Leu Glu Ala Lys Arg Pro

530 535 540Thr Met Leu Lys Ser Tyr Asn Lys Leu Asn Gly Glu Trp Val Glu Val545 550 555 560Thr Pro Cys Asn Phe Glu Ala Gly Ile Lys Ser Gly Ala Val Val Ser

565 570 575Pro Tyr Val Met Gly Val Pro Ser Set Lys Val Leu Ser Asp Ile Thr

580 585590Thr Ser His Tyr Phe Arg Ile Glu Arg Lys Asn Tyr Gly Glu Arg Glu

595 600 605Gln Cys Gln Lys Leu Tyr Gly Val Asn Arg Cys Gln Pro Gln Tyr Ser

610 615 620Ile Leu Ile Leu Val Ser Pro Ile Gly Ala Pro Leu Thr Lys Pro Leu625 630 635 640Pro Pro Lys Pro Leu Asn Leu Ile Tyr Ala Gln Pro Lys Ile Met Lys

645 650 655Asn Thr Pro Gln Pro lle Ile Leu Ser Pro Leu Lys Pro Pro Ser Thr

660 665 670Gly Leu Lys Ala Phe

675(2) SEQ ID NO 629 message

Sequence properties:

(A) length: 113 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...113

(xi) sequence representation: SEQ ID NO 629 Met Ala Lys Met Asn Ala Pro Asp Gly Val Ala Val Trp Val Asn Glu 151015 Asp Arg Cys Lys Gly Cys Asp Ile Cys Val Ser Val Cys Pro Ala Gly

20 25 30Val Leu Gly Met Gly Ile Glu Lys Glu Arg Val Leu Gly Lys Val Ala

35 40 45Lys Val Ala Tyr Pro Glu Ser Cys Ile Gly CysVal Gln Cys Glu Leu

50 55 60His Cys Pro Asp Phe Ala Ile Tyr Val Ala Asp Arg Lys Asp Phe Lys65 70 75 80Phe Ala Lys Val Ser Lys Glu Ala Gln Glu Arg Ser Glu Lys Val Lys

85 90 95Ala Asn Lys Tyr Met Leu Leu Glu Glu Thr Ile Leu Glu Gly Arg Gly

100105110 Lys (2) SEQ ID NO 630 information

Sequence properties:

(A) length: 329 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...329

(xi) sequence representation: 630: Met Thr Thr Lys Arg Val Asn Thr Ala Thr Asn Lys Ile Met Thr Leu 151015 Asn Thr Phe Leu Asp Thr Cys Phe Leu Phe Phe Ile Ser Ile Leu Phe SEQ ID NO

20 25 30Tyr Leu Ser Ile Pro Ile Tyr Pro Asn Lys Val Val Val Val Pro Gln

35 40 45Gly Ser Leu Lys Lys Val Phe Phe Ser Leu Lys Glu Gln Gly Val Asp

50 55 60Ile Asn Ala Leu Asp Leu Leu Leu Leu Arg Leu Met Gly Met Pro Lys65 70 75 80Lys Gly Tyr Ile Asp Met Gly Asp Gly Ala Leu Arg Lys Gly Asp Phe

85 90 95Leu Val Arg Leu Ile Lys Ala Lys Thr Ala Gln Lys Ser Val Thr Leu

100 105 110Ile Pro Gly Glu Thr Arg Tyr Phe Phe Thr Gln Ile Leu Ser Glu Thr

115 120 125Tyr Gln Leu Glu Thr Ser Asp Leu Asn Glu Ala Tyr Glu Ser Ile Ala

130 135 140Pro Arg Leu Asn Gly Ala Val Ile Glu Asp Gly Val Ile Trp Pro Asp145 150 155 160Thr Tyr His Leu Pro Leu Gly Glu Asp Ala Phe Lys Ile Met Gln Thr

165 170 175Leu Ile Gly Gln Ser Met Lys Lys His Glu Ala Leu Ser Lys Gln Trp

180 185 190Leu Gly Tyr Tyr His Lys Glu Glu Trp Phe Glu Lys Ile Ile Leu Ala

195 200 205Ser Ile Val Gln Lys Glu Ala Ala Asn Val Glu Glu Met Pro Leu Ile

210 215 220Ala Ser Val Ile Phe Asn Arg Leu Lys Lys Gly Met Pro Leu Gln Met225 230 235 240Asp Gly Ala Leu Asn Tyr Gln Glu Phe Ser His Ala Lys Val Thr Lys

245 250 255Glu Arg Ile Lys Thr Asp Asn Thr Pro Tyr Asn Thr Tyr Lys Phe Lys

260 265 270Gly Leu Pro Lys Asn Pro Val Gly Ser Val Ser Leu Glu Ala Val Arg

275 280 285Ala Val Val Phe Pro Lys Lys Thr Asp Phe Leu Tyr Phe Val Lys Met

290 295 300Pro Asp Lys Lys Mis Ala Phe Ser Ala Thr Tyr Lys Glu His Leu Lys305310 315 320Asn Ile Asn Ile Ser Asn Asn His Phe

325(2) SEQ ID NO 631 information

Sequence properties:

(A) length: 148 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...148

(xi) sequence representation: SEQ ID NO 631: Lys Phe Met Arg Leu Leu Phe Leu Leu Leu Ser Ala Thr Leu Met Leu 151015 Leu Ala Glu Glu Lys Ile Pro Leu Ser Asp Asp Ala Pro Ile Lys Leu

20 25 30Val His Trp Gln Asn Ala Leu Lys Glu Val Gln Pro Asp Ser Asn Ala

35 40 45Pro Ala Thr Pro Pro Ile Lys Ala Val Gln Thr Thr Leu Thr Phe Glu

50 55 60Thr Pro Phe Asn Lys Thr Pro Lys Ile Met Glu Val Glu Gly Gln Lys65 70 75 80Val Ile Val Leu Lys Asn Ala Gln Leu Asp Ser Lys Lys Thr Met Asp

85 90 95Phe Lys Glu Ala Ser Leu Asn Ala Leu Glu Met Phe Ser Tyr Gln Asn

100 105 110Asp Ile Tyr Leu Leu Ser Lys Lys Ala Lys Ala Gly Leu Glu Ile Gln

115 120125Ala Ser Ser Ser Lys Asp Lys Lys Gin Leu Ala Phe Phe Phe Tyr Pro

130135140 Lys Val Phe Ile145(2) SEQ ID NO:632 information

Sequence properties:

(A) length: 261 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...261

(xi) sequence representation: SEQ ID NO 632: Glu Leu Ile Leu Lys Lys Lys Lys Glu Arg Asn Leu Met Lys Lys Gly 151015 Ser Leu Ala Ile Val Leu Gly Ser Leu Leu Ala Ser Gly Thr Phe Tyr

20 25 30Thr Ala Leu Ala Asp Gly Met Pro Met Lys Gln Gln His Asn Asn Met

35 40 45Gly Glu Ser Val Glu Leu His Phe His Tyr Pro Ile Lys Gly Lys Gln

50 55 60Glu Pro Lys Asn Asn His Leu Val Val Leu Ile Asp Pro Lys Ile Glu65 70 75 80Ala Asn Lys Val Ile Pro Glu Asn Tyr Gln Lys Glu Phe Glu Lys Ser

85 90 95Leu Phe Leu Gln Leu Ser Asn Phe Leu Glu Arg Lys Gly Tyr Ser Val

100 105 110Ser Gln Phe Lys Asp Val Ser Glu Ile Pro Gln Asp Ile Lys Glu Lys

115 120125Ala Leu Leu Val Leu Ar9 Met Asp Gly Asn Val Ala Ile Leu Glu Asp

130 135 140Ile Val Glu Glu Ser Asp Ala Leu Ser Glu Glu Lys Val Ile Asp Met145 150 155 160Ser Ser Gly Tyr Leu Asn Leu Asn Phe Val Glu Pro Lys Ser Glu Asp

165 170 175Ile Ile His Ser Phe Giy Ile Asp Val Ser Lys Ile Lys Ala Val Iie

180 185 190Glu Arg Val Glu Leu Arg Arg Thr Asn Ser Gly Gly Phe Val Pro Lys

195 200 205Thr Phe Val His Arg Ile Lys Glu Thr Asp His Asp Arg Ala Ile Lys

210 215 220Lys Ile Met Asn Gln Ala Tyr His Lys Val Met Ala His Ile Thr Lys225 230 235 240Glu Leu Ser Lys Lys His Met Glu Arg Tyr Glu Lys Val Ser Ser Glu

245 250 255Met Lys Lys Arg Lys

260(2) SEQ ID NO 633 information

Sequence properties:

(A) length: 268 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...268

(xi) sequence representation: 633: Asp Gln Lys Phe Lys Gly Ile Ile Leu Ala Met Lys Ile Ser Val Ser 151015 Lys Asn Asp Leu Glu Asn Thr Leu Arg Tyr Leu Gln Ala Phe Leu Asp SEQ ID NO

20 25 30Lys Lys Asp Ala Ser Ser Ile Ala Ser His Ile His Leu Glu Val Ile

35 40 45Lys Glu Lys Leu Phe Leu Lys Ala Ser Asp Ser Asp Ile Gly Leu Lys

50 55 60Ser Tyr Ile Ser Thr Gln Ser Thr Asp Lys Glu Gly Val Gly Thr Ile65 70 75 80Asn Gly Lys Lys Phe Leu Asp Ile Ile Ser Cys Leu Lys Asp Ser Asn

85 90 95Ile Val Leu Glu Thr Lys Asp Asp Ser Leu Val Ile Lys Gln Asn Lys

100 105 110Ser Ser Phe Lys Leu Pro Met Phe Asp Ala Asp Glu Phe Pro Glu Phe

115 120 125Pro Val Ile Asp Pro Lys Val Ser Leu Glu Ile Asn Ala Pro Phe Leu130 135 140Val Asp Ala Phe Lys Lys Ile Ala Pro Val Ile Glu Gln Thr Ser His145 150 155 160Lys Arg Glu Leu Ala Gly Val Leu Met Gln Phe Asn Gln Lys His Gln

165 170 175Thr Leu Ser Val Val Gly Thr Asp Thr Lys Arg Leu Ser Tyr Thr Gln

180 185 190Leu Glu Lys Ile Ser Ile His Ser Thr Glu Glu Asp Ile Ser Cys Ile

195 200 205Leu Pro Lys Arg Ala Leu Leu Glu Ile Leu Lys Leu Phe Tyr Glu Asn

210 215 220Phe Ser Phe Lys Ser Asp Gly Met Leu Ala Val Val Glu Asn Glu Thr225230 235 240His Ala Phe Phe Thr Lys Leu Ile Asp Gly Asn Tyr Pro Asp Tyr Gln

245 250 255Lys Ile Leu Pro Lys Glu Tyr Thr Ser Leu Ser Leu

260265 (2) SEQ ID NO 634 information

Sequence properties:

(A) length: 416 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...416

The sequence expression: 634: Asn Pro Leu Ile Gln Lys Asn Lys Ser Leu Ser Ile Phe Leu Ile Ser 151015 Asn Ser Val Val Phe Leu Gly Lys Ile Ile Leu His Lys Val Phe Ile SEQ ID NO

20 25 30Met Glu Ala Leu Glu Cys Leu Lys Arg Ile Glu Lys Glu Ser Ile Gln

35 40 45Thr Ile Tyr Ile Asp Pro Pro Tyr Asn Thr Lys Ser Ser Asn Phe Glu

50 55 60Tyr Glu Asp Ala His Ala Asp Tyr Glu Lys Trp Ile Glu Glu His Leu65 70 75 80Ile Leu Ala Lys Ala Val Leu Lys Gln Ser Gly Cys Ile Phe Ile Ser

85 90 95Met Asp Asp Asn Lys Met Ala Glu val Lys Ile Ile Ala Asn Glu Ile

100 105110Phe Gly Thr Arg Asn Phe Leu Gly Thr Phe Ile Thr Lys Gln Ala Thr

115 120 125Arg Ser Asn Ala Lys His Ile Asn Ile Thr His Glu Tyr Val Leu Ser

130 135 140 Pyr Ala Lys Asn Lys Ala Phe Ala Pro Gly Phe Lys Ile Leu Arg Thr145 150 155 160Leu Leu Pro Ile Tyr Ala Lys Ala Leu Lys Asp Leu Met Arg Thr Ile

165 170 175Lys Asn Val Phe Lys Gln Lys Gly Gln Ala Gln Ala Gln Leu Ile Leu

180 185 190Lys Glu Gln Ile Lys Glu Leu Ser Gln Lys Glu His Phe Asn Phe Leu

195 200 205Lys Asn Tyr Asn Leu Val Asp Glu Lys Gly Glu Ile Tyr Phe Ala Lys

210 215 220Asp Leu Ser Thr Pro Ser Asn Pro Arg Ser Val Ala Ile Gln Glu Ile225 230 235 240Asn Leu Phe Leu Glu Pro Leu Lys Ser Arg Gly Trp Ser Ser Asp Glu

245 250 255Lys Leu Lys Glu Leu Tyr Tyr Gln Asn Arg Leu Ile Phe Lys Asn Asn

260 265 270Arg Pro Tyr Glu Lys Tyr Tyr Leu Lyg Glu Ser Gln Asp Asn Cys Leu

275 280 285Ser Val Leu Asp Phe Tyr Ser Arg Gln Gly Thr Lys Asp Leu Glu Lys

290 295 300Leu Gly Leu Lys Gly Leu Phe Lys Thr Pro Lys Pro Val Ala Leu Ile305 310 315 320Lys Tyr Leu Leu Leu Cys Ser Thr Pro Lys Asp Ser Ile Ile Leu Asp

325 330335Phe Phe Ala Gly Ser Gly Thr Thr Ala Gln Ala Val Ile Glu Val Ash

340 345 350Lys Asp Tyr Tyr Leu Asn Trp Ser Phe Tyr Leu Cys Gln Lys Glu Glu

355 360 365Lys Ile Lys Asn Asn Pro Gln Ala Val Ser Ile Leu Lys Asn Lys Gly

370 375 380Tyr Lys Asn Thr Ile Ser Asp Ile Met Leu Leu Arg Leu Glu Lys Ile385 390 395 400Ile Lys Arg Ser Glu Tyr Glu Ile Leu Lys Thr Lys Ser Ile Leu Phe

405410415 (2) SEQ ID NO 635 information

Sequence properties:

(A) length: 76 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...76

(xi) sequence representation: 635: Asn Phe Ser Gly Glu Ser Lys Lys Arg Leu Lys His Pro Ala Pro Phe 151015 Pro Arg Glu Leu Pro Arg Arg Cys Ile Gln Leu Phe Ser Phe Leu Glu SEQ ID NO

20 25 30Asp Thr Ile Phe Asp Pro Phe Ser Gly Ser Gly Thr Thr Ile Leu Glu

35 40 45Ala Asn Ala Leu Gly Arg Phe Ser Val Gly Leu Glu Ile Glu Lys Glu

505560 Tyr Cys Glu Leu Phe Lys LysArg Ile Leu Glu Ser 657075 (2) SEQ ID NO:636 message

Sequence properties:

(A) length: 217 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...217

(xi) sequence representation: 636 SEQ ID NO: Arg Arg Cys Cys Arg Arg Glu Asp Thr Lys Arg Tyr Val Ile Glu Val 15l 015 Val Ile Ser Leu Ser Thr Met Thr Ser Leu Leu Ser Ala Glu Thr Pro

20 25 30Lys Gln Glu Lys Ala Ile Lys Thr Ser Pro Thr Lys Lys Gly Glu Arg

35 40 45Asn Ala Ala Phe Ile Gly Ile Asp Tyr Gln Leu Gly Met Leu Ser Thr

50 55 60Thr Ala Gln Asn Cys Ser His Gly Asn Cys Asn Gly Asn Gln Ser Gly65 70 75 80Ala Tyr Gly Ser Asn Thr Pro Asn Met Pro Thr Ala Ser Asn Pro Thr

85 90 95Gly Gly Leu Thr His Gly Ala Leu Gly Thr Arg Gly Tyr Lys Gly Leu

100 105 110Ser Asn Gln Gln Tyr Ala Ile Asn Gly Phe Gly Phe Val Val Gly Tyr

115 120 125Lys His Phe Phe Lys Lys Ala Pro Gln Phe Gly Met Arg Tyr Tyr Gly

130 135 140Phe Phe Asp Phe Ala Ser Ser Tyr Tyr Lys Tyr Tyr Thr Tyr Asn Asp145 150 155 160Tyr Gly Met Arg Asp Ala Arg Lys Gly Ser Gln Ser Phe Met Phe Gly

165 170 175Tyr Gly Ala Gly Thr Asp Val Leu Phe ASn Pro Ala Ile Phe Asn Arg

180 185 190Glu Lys Leu Ala Phe Gly Val Phe Leu Gly Arg Cys Asp Trp Trp His

195 200 205Leu Leu Gly Ser Asn Lys Leu Leu Phe

210215 (2) SEQ ID NO 637 information

Sequence properties:

(A) length: 107 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...107

(xi) sequence representation: SEQ ID NO:637: Gly Gly Val Cys Gly Val Leu Ser Leu Gln Ala His Leu Ser Phe Glu 151015 Asn Cys Ser Lys Pro Leu Asp Cys ger Leu Phe Ala Thr Thr Cys Thr

20 25 30Pro Gln Asn Pro Ile Gly Ser Cys Met Val Ser Ser Gln Gly Gly Val

35 40 45Cys Gly val Leu Ser Leu Gln Ala His Leu Ser Phe Glu Asn Cys Ser

50 55 60Lys Pro Leu Asp Cys Ser Leu Phe Ala Thr Thr Cys Thr Pro Gln Asn65 70 75 80Pro Ile Gly Ser Tyr Met Val Ser Ser Gln Gly Gly Val Arg Gly Val

85 90 95Leu Ser Leu Gln Ala Arg Leu Ser Phe Lys Asn

100105 (2) SEQ ID NO 638 information

Sequence properties:

(A) length: 384 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...384

(xi) sequence representation: 638: Asn Tyr Ser Asn Lys Asp Asn Pro Met Arg Phe Phe Cys Phe Phe Leu 151015 Phe Phe Leu Thr Phe Ser Asn Ala Gln Ile Met Met Thr Phe Asp Ser SEQ ID NO

20 25 30Gln Thr Asn Ala Lys Leu Ser Arg Ser Asn Glu Gln Leu Ser Asp Met

35 40 45Leu Tyr Lys Leu Asn Glu Ser Leu Arg Ile Tyr Gln Asn Val Leu Ser

50 55 60Asn Asn Gln Asp Gln Leu Lys Glu Ile Lys Lys Ala Ash Ser Thr Leu65 70 75 80Thr Ser Gln Arg Arg Phe Phe Asn Ala Ser Gln Ile Arg Leu Met Asp

85 90 95Thr Asp Ala Leu Leu Lys Gln Ser Ala Leu GluLeu Glu Lys Leu Gln

100 105 110Ala Leu Glu Lys His Leu Lys Glu Ser Met Glu His Glu Arg Leu Ile

115 120 125LyS Glu Ser Gln Ala Leu Phe Leu Gln Glu His Cys Pro Tyr Leu Ser

130 135 140Gly Val Lys Asn Leu Glu Glu Ala Ser Asn Ala Leu Glu Val Gln Glu145 150 155 160Lys Asn Asn Ala Leu Phe Leu Leu Lys Glu Pro Lys Leu Phe His Leu

165 170 175Leu Ser Arg Leu Asp Leu Met Ser Ala Leu Asn Ala Leu Cys Asp Gln

180 185 190Val Leu Glu Asn Glu Ile Gln Asp Gln Gln Ser His Asn Lys Thr Leu

195 200 205Glu Tyr Asn Ala Leu Met Asn His Asp Phe Gln Ala Tyr Lys Ala Met

210 215 220Arg Leu Lys Lys Ile Lys Asn Lys Leu Gln Ser Gln Ile Gln Ala Lys225 230 235 240Glu Asp Ala Leu Lys Thr Phe Leu Pro Leu Glu Lys Arg Pro Glu Thr

245 250 255Leu Gly Ser Ser Asp Cys Cys Asp Lys Glu Asn Leu Lys Ser Cys Ala

260 265 270Asn Gln Leu Gln Gln Arg Tyr Gln Asn Ala Leu Ile Glu Arg Asp Lys

275 280 285Glu Leu Lys Asn Ala Lys Asn Asn Lys Glu Lys His Ala Leu Ile Leu

290 295 300Ala Asn Tyr Glu His Thr Leu Lys Thr Leu Asn Ile Glu Phe Leu Ser305 310 315 320Glu Leu Ser Glu Gln Met Ala Phe Leu Asn Glu Thr Met Ala Leu Asn

325 330 335Ala Gln Val Leu Ala Leu Leu Ala Gln Gln Gln Thr Lys Lys Pro Phe

340 345 350Asn Val Ser Asp Gly Leu Ser Gly Gly Lys Ala Leu Ile Lys Asn Ile

355 360 365Arg Leu Asp Pro His Gly Phe Pro Ser Phe Lys Asn Phe Lys Gln Glu

370375380 (2) SEQ ID NO 639 information

Sequence properties:

(A) length: 298 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...298

(xi) sequence representation: SEQ ID NO 639: Leu Val Phe Lys Lys Pro Phe Phe Lys Asn Arg Leu Leu Asn Val Thr 151015 Asn Lys Leu Lys Phe Val Lys Ile Thr Ile Met Ile Lys Asp Phe Asn

20 25 30His Tyr Cys Ar9 Lys Ile Thr Arg Gly Phe Val Lys Ile Pro Thr Lys

35 40 45Lys Gln Gly Ala Lys Lys Met Lys Lys Ala Gly Phe Leu Phe Leu Ala

50 55 60Ala Met Ala Ile Ile Val Val Ser Leu Asn Ala Lys Asp Pro Asn Val65 70 75 80Leu ArG Lys Ile Val Phe Glu Lys Cys Leu Pro Asn Tyr Glu Lys Asn

85 90 95Gln Asn Pro Ser Pro Cys Ile Glu Val Lys Pro Asp Ala Gly Tyr Val

100 105 110Val Leu Lys Asp Ile Asn Gly Pro Leu Gln Tyr Leu Leu Met Pro Thr

115 120 125Thr His Ile Ser Gly Ile Glu Asn Pro Leu Leu Leu Asp Pro Ser Thr

130 135 140Pro Asn Phe Phe Tyr Leu Ser Trp Gln Ala Arg Asp Phe Met Ser Lys145 150 155 160Lys Tyr Gly Lys Pro Ile Pro Asp Tyr Ala Ile Ser Leu Thr Ile Asn

165 170 175Ser Lys Lys Gly Arg Ser Gln Asn His Phe His Ile His Ile Ser Cys

180 185 190Ile Ser Leu Asp Val Arg Lys Gln Leu Asp Asn Asn Leu Lys Asn Ile

195 200 205Asn Ser Arg Trp Ser Pro Leu Ser Gly Gly Leu Asn Gly His Lys Tyr

210 215 220Leu Ala Arg Arg Val Thr Glu Ser Glu Leu Ala Gln Lys Ser Pro Phe225 230 235 240Val Met Leu Ala Lys Glu Val Pro Asn Ala His Lys Arg Met Gly Asp

245 250 255Tyr Gly Leu Ala Val Val Gln Gln Ser Asp Asn Ser Phe Val Leu Leu

260 265 270Ala Thr Gln Phe Asn Pro Leu Thr Leu Asn Arg Ala Ser Ala Glu Glu

275 280 285Ile Gln Asp His Glu Cys Ala Ile Leu Arg

290295 (2) SEQ ID NO 640 message

Sequence properties:

(A) length: 179 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...179

(xi) sequence representation: SEQ ID NO:640: Leu Arg Arg Leu Ala Leu Asn Thr Met Asn Ser Val Leu Glu Cys Lys 151015 Glu Leu Ala Leu Tyr Gly Gly Ser Phe Asp Pro Leu His Lys Ala His

20 25 30Leu Ala Ile Ile Glu Gln Thr Leu Glu Leu Leu Pro Phe Val Gln Leu

35 40 45Ile Val Leu Pro Ala Tyr Gln Asn Pro Phe Lys Lys Pro Cys Phe Leu

50 55 60Asp Ala Lys Thr Arg Phe Lys Glu Leu Glu Arg Ala Leu Lys Gly Met65 70 75 80Pro Arg Val Leu Leu Ser Asp Phe Glu Ile Lys Gln Glu Arg Ala Val

85 90 95Pro Thr Ile Glu Ser Val Leu His Phe Gln Lys Leu Tyr Arg Pro Lys

100 105 110Thr Leu Tyr Leu Val Ile Gly Ala Asp Cys Leu Arg His Leu Ser Ser

115 120 125Trp Thr Asn Ala Lys Glu Leu Leu Lys Arg Val Glu Leu Val Val Phe

130 135 140Glu Arg Ile Gly Tyr Glu Lys Ile Gln Phe Lys Gly Arg Tyr His Pro145 150155 160Leu Lys Gly Ile Asp Ala Pro Ile Ser Ser Ser Ala Ile Arg Ala Ser

165170175 Leu Gly Val (2) SEQ ID NO 641 message

Sequence properties:

(A) length: 269 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...269

(xi) sequence representation: 641 ID NO: Ser Ser Ile Phe Asp Tyr Asn Tyr Lys Gly Leu His Phe Ser Asn Lys 151015 Arg Tyr Ile Met Leu Gly Ser Val Lys Lys Thr Leu Phe Gly Val Leu

20 25 30Cys Leu Gly Ala Leu Cys Leu Arg Gly Leu Met Ala Glu Pro Asp Ala

35 40 45Lys Glu Leu Val Ser Leu Gly Ile Glu Ser Val Lys Lys Gln Asp Phe

50 55 60Ala Gln Ala Lys Ala His Phe Glu Lys Ala Cys Glu Leu Lys Glu Gly65 70 75 80Phe Gly Cys Val Phe Leu Gly Ala Phe Tyr Glu Glu Gly Lys Gly Val

85 90 95Gly Lys Asp Leu Lys Lys Ala Ile Gln Phe Tyr Thr Lys Gly Cys Glu

100 105 110Leu Asn Asp Gly Tyr Gly Cys Arg Leu Leu Gly Asn Leu Tyr Tyr Asn

115120 125Gly Gln Gly Val Ser Lys Asp Ala Lys Lys Ala Ser Gln Tyr Tyr Ser

130 135 140Lys Ser Cys Glu Leu Asn His Ala Glu Gly Cys Thr Val Leu Gly Ser145 150 155 160Leu His His Tyr Gly Val Gly Thr Pro Lys Asp Leu Arg Lys Ala Leu

165 170 175Asp Leu Tyr Glu Lys Ala Cys Asp Leu Lys Asp Ser Pro Gly Cys Ile

180 185 190Asn Ala Gly Tyr Met Tyr Gly Val Ala Lys Asn Phe Lys Glu Ala Ile

195 200 205Val Arg Tyr Ser Lys Ala Cys Glu Leu Lys Asp Gly Arg Gly Cys Tyr

210 215 220Asn Leu Gly Val Met Gln Tyr Asn Ala Gln Gly Thr Ala Lys Asp Glu225 230 235 240Lys Gln Ala Val Glu Asn Phe Lys Lys Gly Cys Lys Ser Ser Val Lys

245 250 255Glu Ala Cys Asp Ala Leu Lys Glu Leu Lys Ile Glu Leu

260265 (2) SEQ ID NO 642 message

Sequence properties:

(A) length: 86 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...86

(xi) sequence representation: 642 SEQ ID NO: His Phe Asn Ile Phe Thr Glu Asp Asn Arg Glu Ile Ser Gly Ser Thr 151015 Asp Lys Leu Ser Tyr Asn Ala Leu Asn Gly Glu Tyr Lys Leu Leu Gln

20 25 30Asn Ala Val Val Arg Glu Val Gly Lys Ser Asn Val Ile Thr Gly Asp

35 40 45Glu Ile Ile Leu Asn Lys Thr Lys Gly Tyr Ala Asp Val Leu Gly Ser

50 55 60Ala Lys Arg Pro Leu Asn Leu Cys Leu Ile Trp Lys Thr Leu Met Lys65 70 75 80Lys Ile Val Arg Leu Asn

85(2) SEQ ID NO 643 information

Sequence properties:

(A) length: 92 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...92

(xi) sequence representation: SEQ ID NO 643: Pro Lys Ser Pro Lys Lys Ile Val Lys Arg Tyr Glu Lys Ser Ala Trp 151015 Lys Met Pro Lys Glu Asn Thr Thr His Glu Asp Ala Leu Ala Lys Cys

20 25 30Phe Ala Pro Ala Ile Phe Lys Ala Ile Met Leu Asn Lys Leu Ile Leu

35 40 45Ala Val Val Ala Ala Pro Ile Ile Lys Met Leu Lys Leu Ser Lys Glu

50 55 60Ile Trp Trp Lys Lys Met Gly Lys Lys His Ala Ile Asp Phe Lys Met65 70 75 80Arg Ile Lys Ile Leu Ala Ser Leu Ala Pro Ser Phe

8590 (2) SEQ ID NO 644 message

Sequence properties:

(A) length: 185 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...185

(xi) sequence representation: 644: Asn Lys Asp His Leu Met Leu Asn Lys Phe Lys Lys Ile Val Gly Val 151015 Gly Val Leu Val Gly Cys Leu Gly Val Leu Gln Ala Lys Asn Ser Leu SEQ ID NO

20 25 30Phe Val Leu Pro Tyr Glu Gln Arg Asp Ala Leu Asn Ser Leu Ile Ser

35 40 45Gly Ile Ser Ser Ala Arg Glu Asn Val Lys Ile Ala Ile Tyr Ser Phe

50 55 60Thr His Arg Asp Ile Ala Arg Ala Ile Lys Ser Val Ala Ser Arg Gly65 70 75 80Ile Lys Val Gln Ile Ile Tyr Asp Tyr Glu Ser Asn His Asn Asn Lys

85 90 95Gln Ser Thr Ile Gly Tyr Leu Asp Lys Tyr Pro Asn Thr Lys Val Cys

100105 110Leu Leu Lys Gly Leu Lys Ala Lys Asn Gly Asn Tyr Tyr Gly Ile Met

115 120 125His Gln Lys Val Ala Ile Ile Asp Asp Lys Ile Val Phe Leu Gly Ser

130 135 140Ala Asn Trp Ser Lys Asn Ala Phe Glu Asn Asn Tyr Glu Val Phe Leu145 150 155 160Lys Arg Asp Asp Thr Glu Thr Ile Phe Lys Ala Lys Ser Tyr Tyr Gln

165 170 175Lys Met Leu Glu G1y Cys Val Gly Phe

180185 (2) SEQ ID NO 645 information

Sequence properties:

(A) length: 215 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...215

(xi) sequence representation: 645 SEQ ID NO: Gly Arg Thr Met Lys Tyr Leu Trp Leu Phe Leu Ile Tyr Ala Ile Gly 151015 Leu Phe Ala Thr Asp Lys Thr Leu Asp Ile Ile Lys Thr Ile Gln Lys

20 25 30Leu Pro Lys Ile Glu Val Arg Tyr Ser Ile Asp Asn Asp Ala Asn Tyr

35 40 45Ala Leu Lys Leu His Glu Val Leu Ala Asn Asp Leu Lys Thr Ser Gln

50 55 60His Phe Asp Val Ser Gln Asn Lys GluGln Gly Ala Ile Asn Tyr Ala65 70 75 80Glu Leu Lys Asp Lys Lys Val His Leu Val Ala Leu Val Ser Val Ala

85 90 95Val Glu Asn Gly Asn Lys Ile Ser Arg Leu Lys Leu Tyr Asp Val Asp

100 105 110Thr Gly Thr Leu Lys Lys Thr Phe Asp Tyr Pro Ile Val Ser Leu Asp

115 120 125Leu Tyr Pro Phe Ala Ala His Asn Met Ala Ile Val Val Asn Asp Tyr

130 135 140Leu Lys Ala Pro Ser Ile Ala Trp Met Lys Arg Leu Ile Val Phe Ser145 150 155 160Lys Tyr Ile Gly Pro Gly Ile Thr Asn Ile Ala Leu Ala Asp Tyr Thr

165 170 175Met Arg Tyr Gln Lys Glu Ile Ile Lys Asn Asn Arg Leu Asn Ile Phe

180 185 190Pro Lys Trp Ala Asn Ala Glu Gln Thr Glu Phe Tyr Tyr Thr Gln Met

195 200 205Ala Glu Lys Arg Pro Trp Phe

210215 (2) SEQ ID NO 646 message

Sequence properties:

(A) length: 176 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...176

(xi) sequence representation: 646: Ala Ala Met Met Phe Asn Asn Asp Ile Asp Ser Ala Thr Gly Phe Tyr 151015 Lys Pro Leu Ile Lys Ile Asn Ser Ala Gln Asp Leu Ile Lys Asn Thr SEQ ID NO

20 25 30Glu His Val Leu Leu Lys Ala Lys Ile Ile Gly Tyr Gly Asn Val Ser

35 40 45Thr Gly Thr Asn Gly Ile Ser Asn Val Asn Leu Glu Glu Gln Phe Lys

50 55 60Glu Arg Leu Ala Leu Tyr Asn Asn Asn Asn Arg Met Asp Thr Cys Val65 70 75 80Val Arg Asn Thr Asp Asp Ile Lys Ala Cys Gly Met Ala Ile Gly Asn

85 90 95Gln Ser Met Val Asn Asn Pro Asp Asn Tyr Lys Tyr Leu Ile Gly Lys100 165 110Ala Trp Arg Asn Ile Gly Ile Ser Lys Thr Ala Asn Gly Ser Lys Ile

115 120 125Ser Val Tyr Tyr Leu Gly Asn Ser Thr Pro Thr Glu Asn Gly Gly Asn

130 135 140Thr Thr Asn Leu Pro Thr Asn Thr Thr Asn Asn Ala His Ser Ala Asn145 150 155 160Tyr Ala Leu Val Lys Asn Ala Pro Phe Ala His Asn Thr Thr Pro Asn

165170175 (2) SEQ ID NO:647 message

Sequence properties:

(A) length: 188 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...188

(xi) sequence representation: SEQ ID NO 647: Ile Phe Arg Ala Phe Arg Arg Gly Phe Phe Arg Lys Thr Phe Ala Tyr 151015 Arg Phe Thr Ala His His Asp Phe Met Leu Glu Arg Met Asn Arg Arg

20 25 30Asn Arg Thr Lys Ser Asp Arg Glu Leu Leu Glu Ile Ile Ala Ser Lys

35 40 45Asn Phe Ala Ile Gly Thr Asp Phe Ile Val Gly His Pro Gly Glu Ser

50 55 60Glu Ser Val Phe Glu Lys Ala Phe Lys Asn Leu Glu Ser Leu Pro Leu65 70 75 80Thr His Ile His Pro Phe Ile Tyr Ser Lys Arg Lys Asp Thr Pro Ser

85 90 95Ser Leu Met Arg Asp Ser Val Ser Leu Glu Asp Ser Lys Lys Arg Leu

100 105 110Asn Ala Ile Lys Asp Leu Ile Phe His Lys Asn Lys Ala Phe Arg Gln

115 120 125Leu Gln Leu Lys Leu Asn Thr Pro Leu Lys Ala Leu Val Glu Ala Gln

130 135 140Lys Asp Gly Glu Phe Lys Ala Leu Asp Gln Phe Phe Asn Pro Ile Lys145 150 155 160Ile Lys Ser Asp Lys Pro Leu Arg Ala Ser Phe Leu Glu Ile Lys Glu

165 170 175Tyr Glu Ile Lys Glu Arg Glu Asn His Ala Val Phe

180185 (2) SEQ ID NO 648 information

Sequence properties:

(A) length: 79 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...79

(xi) sequence representation: 648 of SEQ ID NO: Lys Ala Leu Pro Gln Gly Arg Asn Arg Met Arg Ser Asp Val Glu Val 151015 Leu Ser Pro Leu His Lys Ile Asp Glu Lys Tyr Leu Phe His Leu Lys

20 25 30Ile Ala Gly Glu Leu Ala Ser Met Gly Lys Ile Leu Ser Val Tyr Leu

35 40 45Ala His Lys His Ser Ala Tyr Phe Ile Leu Asn Ala Leu Ser Tyr Gly

505560 Phe Ser His Gln Asp Arg Ala Ile Ile Cys Leu Leu Gly Ala Ile 657075 (2) SEQ ID NO:649 information

Sequence properties:

(A) length: 235 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...235

(xi) sequence representation: SEQ ID NO 649: Lys Gly Thr Lys Met Lys Lys Val Tyr Phe Lys Thr Phe Gly Cys Arg 151015 Thr Asn Leu Phe Asp Thr Gln Val Met Gly Glu Asn Leu Lys Asp Phe

20 25 30Ser Ala Thr Leu Glu Glu Gln Glu Ala Asp Ile Ile Ile Ile Asn Ser

35 40 45Cys Thr Val Thr Asn Gly Thr Asp Ser Ala Val Arg Ser Tyr Ala Arg

50 55 60Lys Met Ala Arg Leu Asp Lys Glu Val Leu Phe Thr Gly Cys Gly Val65 70 75 80Lys Thr Gln Gly Lys Glu Leu Phe Glu Lys Gly Leu Leu Lys Gly Val

85 90 95Phe Gly His Asp Asn Lys Glu Lys Ile Asn Ala Leu Leu Gln Glu Lys

100 105 110Lys Arg Phe Phe Ile Asp Asp Asn Leu Glu Asn Lys His Leu Asp Thr

115 120 125Thr Met Val Ser Glu Phe Val Gly Lys Thr Arg Ala Phe Ile Lys Ile

130 135 140Gln Glu Gly Cys Asp Phe Asp Cys Asn Tyr Cys Ile Ile Pro Ser Val145 150 155 160Arg Gly Arg Ala Arg Ser Phe Glu Lys Arg Lys Ile Leu Glu Gln Val

165 170 175Gly Leu Leu Cys Ser Gln Gly Val Gln Glu Val Val Leu Thr Gly Thr

180 185 190Asn Val Gly Ser Tyr Gly Lys Asp Arg Gly Ser Asn Ile Ala Arg Leu

195 200 205Ile Lys Lys Leu Ser Gln Ile Thr Gly Leu Lys Arg Ile Arg Ile Gly

210215220 SerLeu Asp Leu Ile Lys Ser Thr Met Asn Phe 225230235 (2) SEQ ID NO 650 information

Sequence properties:

(A) length: 101 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...101

(xi) sequence representation: 650: Val Thr Ala Leu Ala Thr Arg Ile Gly Arg Ser Phe Ala Tyr Trp Ala 151015 Gln Phe Ser His Lys Lys Ile Leu Lys Asp Tyr Val Ile Ala His Met SEQ ID NO

20 25 30Ser Ala Met Met Pro Ser Leu Leu Thr Leu Gln Trp Leu Ser Phe Ile

35 40 45Leu Ser Leu Ala Glu Asn Leu Cys Leu Thr Asp Ser His His Leu Lys

50 55 60Tyr Thr Leu Glu Lys Asn Lys Leu Val Ile His Ser Asn Asp Ala Leu65 70 75 80Tyr Leu Ala Lys Glu Met Leu Pro Lys Leu Ile Lys Pro Ile Pro Trp

85 90 95Thr Ile Glu Phe Ala

100(2) SEQ ID NO 651 message

Sequence properties:

(A) length: 409 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...409

(xi) sequence representation: SEQ ID NO 651: Ser Asp Ala Phe Leu Ile Ile Gln Asp Phe Lys Glu Gln Arg Ile Ile 151015 Mis Lys Ile Ile Gln Thr His Phe Lys Arg Met Arg Val Val Leu Ser

20 25 30Val Lys Arg Asp Ser Glu Lys Thr Leu Glu Asn Asn Glu Glu Asn Lys

35 40 45Asp Glu Lys Leu Ile Leu Ile Asp Glu Phe Glu Val Leu Ala Asn Lys

50 55 60Phe Ile Ser Arg Leu Pro Asn Ile Pro Ser Thr Pro Arg Glu Phe Gly65 70 75 80Leu Gly Lys Gly Glu Ile Met Glu Ile Asp Val Pro Phe Gly Ser Ile

85 90 95Phe Ala Tyr Arg His Ile Gly Ser Ile Arg Gln Lys Glu Tyr Arg Ile

100 105 110Val Gly Leu Tyr Arg Asn Asp Val Leu Leu Leu Ser Thr Lys Ser Leu

115 120 125Val Ile Gln Pro Arg Asp Ile Leu Leu Val Ala Gly Asn Pro Glu Ile

130 135 140Leu Asn Ala Val Tyr His Gln Val Lys Ser Asn Val Gly Gln Phe Pro145 150 155 160Ala Pro Phe Gly Lys Ser Ile Tyr Leu Tyr Ile Asp Met Arg Leu Gln

165 170175Ser Arg Lys Ala Met Met Arg Asp Val Tyr Gln Ala Leu Phe Leu His

180 185 190Lys Arg Leu Lys Ser Tyr Lys Leu Tyr Ile Gln Val Leu His Pro Thr

195 200 205Ser Pro Lys Phe Tyr His Lys Phe Leu Ser Leu Glu Thr Glu Ser Ile

210 215 220Glu Val Asn Phe Asp Phe Tyr Gly Lys Ser Phe Ile Gln Lys Leu His225 230 235 240Glu Asp His Gln Lys Lys Met Gly Leu Ile Val Val Gly ArG Glu Leu

245 250 255Phe Phe Leu Lys Lys His Arg Arg Ala Leu His Lys Thr Ala Thr Pro

260 265 270Val Tyr Lys Thr Asn Thr Ser Gly Leu Ser Lys Thr Thr Gln Ser Ile

275 280 285Val Val Leu Asn Glu Ser Leu Ser Ile Asn Glu Asp Met Ser Ser val

290 295 300Ile Phe Asp Val Ser Met Gln Met Asp Leu Gly Leu Leu Leu Tyr Asp305 310 315 320Phe Asp Pro Asn Lys His Tyr Lys Asn Glu Ile Val Asn His Tyr Glu

325 330 335Asn Leu Ala Asn Thr Phe Asn Arg Lys Ile Glu Ile Phe Gln Thr Asp

340 345 350Ile Lys Asn Pro Ile Met Tyr Leu Asn Ser Leu Arg Asn Pro lle Leu

355 360 365His Phe Met Pro Phe Glu Glu Cys Ile Thr Gln Thr Arg Tyr Leu Trp

370 375 380Phe Leu Ser Thr Lys Val Glu Lys Leu Ala Phe Leu Asn Asp Asp His385 390 395 400Pro GlnIle Phe Ile Pro Val Ala Glu

405(2) SEQ ID NO 652 message

Sequence properties:

(A) length: 64 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...64

(xi) sequence representation: 652: Pro Asn Glu Ala Ser Ala Ala Val Asn Val Gly Tyr Lys Ile Ser Lys 151015 Ser Leu Thr Ala Ser Val Lys Leu Glu Tyr Leu Gly Val Met Thr His SEQ ID NO

20 25 30Ser Gly Phe Thr Val Gly Ser Tyr Arg Pro Thr Pro Gly Ser Lys Ala

35 40 45Leu Tyr Ser Asp Arg Ser His Leu Met Tnr Thr Leu Ser Ala Lys Val

505560 (2) SEQ ID NO:653 information

Sequence properties:

(A) length: 85 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...85

(xi) sequence representation: 653: Ser Ile Val Tyr Gly Lys Asn Lys Leu Phe Ser Asp Glu Phe Tyr Glu 151015 Lys Ile Glu Asp Ile Leu Thr Asn Asn Asn Pro Arg Tyr Lys Gln Val SEQ ID NO

20 25 30Cys Ile Ile Phe Asp Ala Asp Ile Lys Lys Glu Ash Gln Glu Ser Asp

35 40 45Ala Gly Phe Asp Asn Lys Leu Lys His Ile ArG Glu Lys Phe Lys Glu

50 55 60Lys Gly Thr Asp Phe Pro Lys Glu Gln Ile Phe Tyr Ser Leu Thr Ile65 70 75 80Lys Met Meu Ala Ile

85(2) SEQ ID NO 654 message

Sequence properties:

(A) length: 146 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...146

(xi) sequence representation: SEQ ID NO 654: Val Gln Ala Phe Asp Tyr Lys Ile Glu Val Leu Ala Glu Ser Phe Ser 151015 Lys Val Gly Phe Asn Lys Lys Lys Ile Asp Ile Ala Arg Gly Ile Tyr

20 25 30Pro Thr Glu Thr Phe Val Thr Ala Val Gly Gln Gly Asn Ile Tyr Ala

35 4045Asp Phe Leu Ser Lys Ser Leu Lys Asp Gln Gly His Val Leu Glu Gly

50 55 60Lys Val Gly Gly Thr Ile Gly Gly Ile Ala Tyr Asp Ser Thr Lys Phe65 70 75 80Asn Gln Gly Gly Ser Val Ile Tyr Asn Tyr Ile Gly Tyr Trp Asp Gly

85 90 95Tyr Leu Gly Gly Lys Arg Ala Leu Leu Asp Gly Thr Ser Ile His Glu

100 105 110Cys Aia Leu Gly Ser Asp Gly Lys Val Ile Asp Ser Ile Ala Cys Gly

115 120 125Asn Ala Arg Ala Asn Lys Ile Arg Arg Asn Tyr Leu Met Asn Thr Pro

130135140 Phe Ser145(2) SEQ ID NO:655 information

Sequence properties:

(A) length: 247 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...247

(xi) sequence representation: SEQ ID NO. 655: Phe Arg Tyr Lys Asp Ile Phe Ala Ala Lys Gly Gly Arg Tyr Gln Ser 151015 Asn Ala Pro Tyr Met Ser Ser Tyr Thr Gln Gly Phe Glu Ile Ser Ala

20 25 30Lys Ile Lys Asp Lys Asn Glu Gly Ser His Lys Leu Trp Trp Phe Ser

3540 45Ser Trp Gly Arg Ala Phe Ala Tyr Gly Glu Trp Ile Tyr Asp Phe Tyr

50 55 60Ser Pro Arg Thr val Ile Lys Asn Gly Arg Thr Leu Asn Tyr Gly Ile65 70 75 80His Leu Val Asp Tyr Thr Tyr Glu Arg Lys Gly Val Ser Val Ser Pro

85 90 95Phe Phe Gln Phe Ser Pro Gly Thr Tyr Tyr Ser Pro Gly Val Ala Val

100 105 110Gly Tyr Asp Ser Asn Pro Asn Phe Asn Gly Val Gly Phe Arg Ser Glu

115 120 125Thr Lys Ala Tyr Ile Leu Leu Pro Val His Ala Pro Leu Lys Arg Asp

130 135 140Thr Tyr Arg Tyr Ala Val Lys Ala Gly Thr Ala Gly Gln Ser Leu Leu145 150 155 160Ile Arg Gln Arg Phe Asp Tyr Asn Glu Phe Asn Phe Gly Gly Ala Phe

165 170 175Tyr Lys Val Trp Lys Asn Ala Asn Ala Tyr Ile Gly Thr Thr Gly Asn

180 185 190Pro Leu Gly Ile Asp Phe Trp Thr Asn Ser Val Tyr Asp Ile Gly Gln

195 200 205Ala Leu Ser His Val Val Thr Ala Asp Ala Val Ser Gly Trp Val Phe

210 215 220Gly Gly Gly Val His Lys Lys Trp Leu Trp Gly Thr Leu Trp Arg Trp225 230 235 240Thr Ser Gly Ala Leu Ala Lys

245(2) SEQ ID NO 656 message

Sequence properties:

(A) length: 130 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...130

(xi) sequence representation: SEQ ID NO:656: Phe Ser Gln Arg Thr Asn Leu Leu Phe Pro Asn Asn Gln Asp Asp Gly 151015 Asp Leu Glu Thr Leu Leu Leu Glu Ile Ala Lys His Asp Glu Phe Leu

20 25 30Lys Cys Phe Glu Gly Tyr Leu Glu Cys Ile Lys Ser Lys Glu His Tyr

35 40 45Lys Pro Ile Lys Asn Ile Arg Lys Asn Met Leu Tyr Ala Tyr Leu Glu

50 55 60Ala Leu Gly Leu Glu Asn Leu Thr Lys Thr Asn Ile Asp Val Phe Asp65 70 75 80Ser Lys Gly Lys Ile Lys Ser Arg Tyr Glu Glu Asn Tyr Lys Lys Leu

85 90 95Thr Glu Glu Val Ile Asp Phe Ser Ser Asn Ser Leu Ile Pro Leu Lys

100 105 110Asn Phe Leu Gly Gln Phe Ala Glu Asn Lys Gln Lys Thr Asn Pro Lys

115 120 125Ile Phe

130(2) SEQ ID NO 657 information

Sequence properties:

(A) length: 71 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...71

(xi) sequence representation: SEQ ID NO 657: Ile Tyr Phe Ser Ala Lys Arg Phe Asn Thr Lys Asn Thr His Gly Thr 151015 Gly Cys Thr Leu Ser Ser Leu Ile Val Gly Leu Leu Ala Gln Gly Leu

20 25 30Asp Leu Lys Asn Ala Ile Thr Lys Ala Lys Glu Leu Leu Thr Ile Ile

35 40 45Ile Gln Asn Pro Leu Asn Ile Gly His Gly His Gly Pro Leu Asn Leu

505560 Trp Ser Ile Lys Lys His Val 6570 (2) SEQ ID NO:658 information

Sequence properties:

(A) length: 233 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...233

(xi) sequence representation: SEQ ID NO 658: Arg Pro Ser Phe Gln Lys Arg Cys Ala His Phe Asn Ala Thr Leu Pro 151015 Ile Leu Leu Lys Val Leu Glu Lys Gln Asp Lys Asp Leu Phe Leu Leu

20 25 30Gln Val Gly Asn Arg Ile Ile Pro Thr Lys Ser Glu Gln Glu Leu Lys

35 40 45Ile Asn Gln Pro Tyr Phe Ala Thr Met Gln Arg Asn Gln Leu Gly Asp

50 55 60Ile Val Leu Lys Asn Leu Val Pro Ala Pro Lys Ile Leu Asp Ala Leu65 70 75 80Asp Asp Leu Pro Val Ile Glu Met Lys Lys Leu Lys Glu Ile Leu Ser

85 90 95Ala Lys Asp Asn Thr Pro Leu Lys Glu Tyr Lys Glu Leu Leu Ser Glu

100 105 110Lys Leu Ile His Ala Lys Ser Ser Gln Glu Phe Leu Asn Thr Ala Asn

115 120 125Met Leu Leu Ser Leu Gln Ser Gln Val Leu Ser Phe Val Val Glu Asn

130 135 140Glu Arg Lys Lys Ala Phe Leu Gln Met Lys Ala Lys Lys Gln Ser Val145 150 155 160Asp Phe Tyr Ala Leu Tyr Pro Asn Leu Gly Glu Ile Gly Gly Val Ile

165 170 175Tyr Leu Lys Glu Lys Glu Lys Gln Leu Phe Leu Lys Thr Thr Leu Gln

180 185 190Arg Thr Lys Glu Val Leu Lys Glu Ala Gln Asn Thr Leu Leu Gly Phe

195 200 205Ser Phe Val Glu Ile Val Cys Glu Lys Thr Pro Met Leu Phe Ala Phe

210215220 Glu Asp Arg Leu Leu Asp Thr Leu Gly 225230 (2) SEQ ID NO:659 information

Sequence properties:

(A) length: 154 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...154

(xi) sequence representation: 659: Leu Leu Glu Met Ile Phe Arg Ser Arg Arg Ser Lys Trp Gly Ala Leu 151015 Cys Asn Ala Gln Ile Ile Glu Cys Val Ala Asn Ala Leu Glu Thr Cys SEQ ID NO

20 25 30Asp Phe Gly Leu Cys Val Leu Asp Pro Val Met Val Ala Lys Asn Gly

35 40 45Ala Leu Leu Leu Glu Glu Glu Ala Ile Leu Ser Leu Lys Lys Arg Leu

50 55 60Leu Pro Lys Thr Asn Leu Leu Thr Pro Asn Leu Pro Glu Val Tyr Ala65 70 75 80Leu Thr Gly Val Gln Ala Arg Asp Asp Lys Ser Ala Ser Lys Ala Met

85 90 95Gly Val Leu Arg Asp Leu Gly Val Lys Asn Ala Val Ile Lys Gly Gly

100 105 110His Thr Glu His Phe Gln Gly Glu Phe Ser Asn Asp Trp Val Phe Leu

115 120 125Glu Asp Ala Glu Phe Thr Leu Ala Pro Ser Asp Ser Thr Pro Lys Thr

130135140 Arg Met Ala Arg Val Val Leu Cys Leu Ala 145150 (2) SEQ ID NO:660 information

Sequence properties:

(A) length: 323 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...323

(xi) sequence representation: 660 SEQ ID NO: Trp Leu Gln Ser Arg Cys Phe Arg Asp Ser Ala Phe Cys Leu Ser Ser 151015 Glu Lys Leu Phe Gly Lys Asn Leu Asn Lys Val Val Ile Leu Ala Leu

20 25 30Arg Asp Ile Ile His Glu Tyr Gly His Thr Leu Gly Tyr Thr His Asn

35 40 45Gly Asn Met Thr Tyr Gln Arg Val Arg Leu Cys Gln Glu Gly Asn Gly

50 55 60 Pro Glu Ala Arg Cys Glu Gly Gly His Glu Val Glu Lys Asn Gly Lys65 70 75 80Glu Glu Leu Glu Phe Ser Asn Gly His Glu Val Arg Asp His Asp Gly

85 90 95Tyr Thr Tyr Asp Val Cys Ser Arg Phe Gly Gly Lys Asn Gln Pro Ala

100 105 110Phe Pro Ser Asn Tyr Pro Asn Ser Ile Tyr Thr Asn Cys Ala Gln Val

115 120 125Pro Ala Gly Leu Ile Gly Val Thr Thr Ala Val Trp Gln Gln Leu Ile

130 135 140Asn Gln Asn Ala Leu Pro Ile Asn Phe Ala Asn LeuAsn Ser Gln Thr145 150 155 160Ser His Leu Asn Ala Gly Leu Asn Ala Gln Asn Phe Ala Thr Ser Met

165 170 175Val Ser Ala Ile Ala Gln Asn Phe Ser Thr Thr Ser Thr Thr Thr Tyr

180 185 190Arg Ser Ser Ser Lys Asn Phe Arg Ser Pro Ile Leu Gly Val Asn Val

195 200 205Lys Ile Gly Tyr Gln His Tyr Phe Asn Asp Tyr Ile Gly Leu Ala Tyr

210 215 220Tyr Gly Ile Ile Gln Tyr Asn Tyr Ala Gln Ala Asn Asp Glu Lys Ile225 230 235 240Gln Gln Leu Ser Tyr Gly Gly Gly Met Asp Val Leu Phe Asp Phe Ile

245 250 255Thr Thr Tyr Thr Asn Lys Lys Gln Asp His Pro Thr Lys Lys Val Phe

260 265 270Ala Ser Ser Phe Gly Val Phe Gly Gly Leu Arg Gly Leu Tyr Asn Ser

275 280 285Tyr Tyr Val Phe Asn Gln Val Lys Gly Ser Gly Asn Leu Asp Ile Val

290295300 Thr Gly Phe Asn Tyr Arg Tyr Lys His Ser Lys Tyr Ser Ile Ala Leu 305310315320 Ala Phe Leu (2) SEQ ID NO:661 information

Sequence properties:

(A) length: 142 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...142

(xi) sequence representation: SEQ ID NO 661: Tyr Asp Phe Leu Gly Val Ser Leu His Ala Leu Ser Pro Leu Glu Glu 151015 Gln Glu Phe Leu Ile Ser Tyr Arg Leu Lys Ile Val Asp Ser Arg Val

20 25 30Met Gly Glu Glu Tyr Ser Val Ser Lys Pro Ile Val Ser Arg Ile Lys

35 40 45Thr Ala Pro Tyr Val Leu Asp Tyr His Cys Ser Ile Ile Thr Arg Asn

50 55 60Leu Pro Asp Leu Lys Asn Pro Leu Leu Gln Ile Lys Leu Glu Arg Phe65 70 75 80Leu Leu Glu Ile Ala Leu Lys Lys Glu Lys Glu Arg Val Ile Asp Cys

85 90 95Leu Leu Lys Ser Gln Val Ala Ile Thr His Tyr Asp His Ser Tyr Lys

100 105 110Asn Gly Thr Thr Thr Thr Ser Ile Leu Asn Leu Lys Ala Leu Ser Val

115 120 125Lys Ala Ser Leu Asp Gly Arg Tyr Ala Val Phe Arg Tyr Phe

130135140 (2) SEQ ID NO 662 information

Sequence properties:

(A) length: 344 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...344

(xi) sequence representation: 662: Glu Trp Leu Met Leu Lys Lys Ile Phs Tyr Gly Phe Ile Val Leu Phe 151015 Leu Ile Ile Val Gly Leu Leu Ala Val Leu Val Ala Gln Val Trp Val SEQ ID NO

20 25 30Thr Thr Asp Lys Asp lle Ala Lys Ile Lys Asp Tyr Arg Pro Ser Val

35 40 45Ala Ser Gln Ile Leu Asp Arg Lys Gly Arg Leu Ile Ala Asn lle Tyr

50 55 60Asp Lys Glu Phe Arg Phe Tyr Ala Arg Phe Glu Glu Ile Pro Pro Arg65 70 75 80Phe Val Glu Ser Leu Leu Ala Val Glu Asp Thr Leu Phe Phe Glu His

85 90 95Gly Gly Ile Asn Leu Asp Ala Val Met Arg Ala Met Ile Lys Asn Ala

100 105 110Lys Ser Gly Arg Tyr Thr Glu Gly Gly Ser Thr Leu Thr Gln Gln Leu

115 120 125Val Lys Asn Met Val Leu Thr Arg Glu Lys Thr Leu Thr Arg Lys Leu

130 135 140Lys Glu Ala Ile Ile Ser Ile Arg Ile Glu Lys Val Leu Ser Lys Glu145 150 155 160Glu Ile Leu Glu Arg Tyr Leu Asn Gln Thr Phe Phe Gly His Gly Tyr

165 170 175Tyr Gly Val Lys Thr Ala Ser Leu Gly Tyr Phe Lys Lys Pro Leu Asp

180 185 190Lys Leu Thr Leu Lys Glu Ile Thr Met Leu Val Ala Leu Pro Arg Ala

195 200205Pro Ser Phe Tyr Asp Pro Thr Lys Asn Leu Glu Phe Ser Leu Ser Arg

210 215 220Ala Asn Asp Ile Leu Arg Arg Leu Tyr Ser Leu Gly Trp Ile Ser Ser225 230 235 240Asn Glu Leu Lys Ser Ala Leu Asn Glu Val Pro Ile Val Tyr Asn Gln

245 250 255Thr Ser Thr Gln Asn Ile Ala Pro Tyr Val Val Asp Glu Val Leu Lys

260 265 270Gln Leu Asp Gln Leu Asp Gly Leu Lys Thr Gln Gly Tyr Thr Ile Lys

275 280 285Leu Thr Ile Asp Leu Asp Tyr Gln Arg Leu Ala Leu Glu Ser Leu Arg

290 295 300Phe Gly His Gln Lys Ile Leu Glu Lys Ile Ala Lys Glu Lys Pro Lys305 310 315 320Thr Asn Ala Ser Asn Asp Lys Asp Glu Asp Asn Leu Asn Ala Gln His

325 330 335Asp Ser Tyr Arg Asn Glu His Arg

340(2) SEQ ID NO 663 information

Sequence properties:

(A) length: 117 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...117

(xi) sequence representation: 663: Thr Pro Ser Met Ile Val Thr Glu Thr Ser Thr Gly Lys Ile Leu Ala 151015 Leu Val Gly Gly Ile Asp Tyr Lys Lys Ser Ala Phe Asn Arg Ala Thr SEQ ID NO

20 25 30Gln Ala Lys Arg Gln Phe Gly Ser Ala Ile Lys Pro Phe Val Tyr Gln

35 40 45Ile Ala Phe Asp Asn Gly Tyr Ser Thr Thr Ser Lys Ile Pro Asp Thr

50 55 60Ala Arg Asn Phe Glu Asn Gly Asn Tyr Ser Lys Asn Ser Val Gln Asn65 70 75 80His Ala Trp His Pro Ser Asn Tyr Thr Arg Lys Phe Leu Gly Leu Val

85 90 95Thr Leu Gln Glu Ala Leu Ser His Ser Leu Asn Leu Ala Thr Ile Asn

100 105 110Leu Ala Ile Ala Trp

115(2) SEQ ID NO 664 information

Sequence properties:

(A) length: 208 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...208

(xi) sequence representation: 664: Pro Arg Asp His Thr Tyr Ser Leu Glu Asp Ser Thr Pro His Gly Ser 151015 Leu Leu Gly Arg Asn Gly Val Thr Leu Asn Ile Arg Gln Val Phe Trp SEQ ID NO

20 25 30Trp Asp Asn Phe Asn Trp Ser Ile Gly Phe Tyr Asn Thr Phe Gly Asn

35 40 45Ser Asp Ala Phe Leu Gly Ser His Thr Met Pro Arg Gly Asn Asn Thr

50 55 60Ser Tyr Ile Ser Asn Glu Ile Ser Val Thr Thr Arg His Ala Gly Met65 70 75 80Ile Gly Tyr Asp Phe Trp Asp Asn Thr Ala Tyr Asp Gly Leu Ala Asp

85 90 95Ala Ile Thr Asn Ala Asn Thr Pne Thr Phe Tyr Thr Ser Val Gly Gly

100 105 110Ile His Lys Arg Phe Ala Trp His Val Phe Gly Arg Val Ser His Ala

115 120 125Asn Lys Asn Ala Leu Gly Gln Val Gly Arg Ala Asn Glu Tyr Ser Leu

130 135 140Gln Phe Asn Ala Ser Tyr Ala Ser Thr Glu Ser Val Leu Leu Asn Phe145 150 155 160Arg Ile Thr Tyr Tyr Gly Ala Arg Ile Asn Lys Gly Tyr Gln Ala Gly

165 170 175Tyr Phe Gly Ala Pro Lys Phe Asn Asn Pro Asp Gly Asp Phe Ser Ala

180 185 190Asn Tyr Gln Asp Arg Ser Tyr Met Met Thr Asn Leu Thr Leu Lys Phe

195200205 (2) SEQ ID NO:665 information

Sequence properties:

(A) length: 132 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...132

(xi) sequence representation: SEQ ID NO:665: Pro Arg Ile His Asp Met Gly Asp Leu Asp Ser Leu Asn Ile Ser Pro 151015 Asp Pro Asn Thr Pro Thr Leu Leu Ile Leu Ser Ala Leu Asp Asn Ser

20 25 30Leu Lys Asp Tyr Ala Pro Thr Phe Asn Val Leu Lys Lys Thr Phe Lys

35 40 45Asp Arg Leu Arg Val Leu Ile Leu Leu Asn Gln Pro Tyr Ser Ser Asp

50 55 60Ala Ile Lys Gly Phe Ile Ala Pro Ser Gln Thr Asp Leu Met Ile Leu65 70 75 80Asn Pro Lys Asp Thr Ala Leu Phe Asp His Leu Asn His Asp Ala Leu

85 90 95Asn His Ser Phe Asn Met Leu Leu Tyr Asp Lys His Gln Leu Ile Lys

100 105 110Met Tyr Gln Gly Ile Val Pro Ala Glu Met Leu Gln Phe Asp Ile Ser

115 120 125Asn Leu Lys Asp

130(2) SEQ ID NO 666 information

Sequence properties:

(A) length: 122 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...122

(xi) sequence representation: SEQ ID NO 666: Arg Arg Ser Leu Tyr Tyr Val Phe Ile Lys Ser Tyr Ala Ile Leu Ala 151015 Glu Ala Thr Ala Arg Phe Ala Gly Asp Tyr Ala Thr Glu Asn Leu Thr

20 25 30Ser Arg Ile Ala Leu Pro Cys Ser Asp Tyr Val Gly Arg Val Ile Gly

35 40 45Lys Asp Gly Lys Asn Ile Glu Ala Phe Lys Lys Ile Ser Gly Val Asp

50 55 60Ile Glu Phe Ser Glu Asp Ser Ser Glu Leu Cys Leu Ser Ser Phe Asn65 70 75 80Ile Tyr Arg Arg Glu Val Ala Ser Glu Tnr Ile Lys Ile Leu Ile Glu

85 90 95Asp Gly Arg Ile Gln Pro Asn Arg Ile Glu Glu Val Tyr Pro Lys Ile

100 105 110His Pro Gln His Gly Lys Arg Ile Ala Phe

115120 (2) message of SEQ ID NO 667

Sequence properties:

(A) length: 250 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...250

(xi) sequence representation: 667: Lys Thr Ala Val Ser Ser Leu Thr Gly Leu Lys Arg Phe Ile Leu Lys 151015 Phe Thr Arg Asn Met Glu Lys Glu Leu Leu Ser Glu Gly Glu Ser Val SEQ ID NO

20 25 30Val Leu Glu Ieu Glu Leu Gly Thr Met Glu ASp Glu Leu Lys Ile Leu

35 40 45Ile Gly Lys Met Arg Tyr Arg Phe Ser Phe Gly Gln Asn Ala Leu Gln

50 55 60His Ser Lys Glu Ile Ala Leu Leu Ser Gly Leu Ile Ala Glu Gln Leu65 70 75 80Gly Gly Asp Lys Lys Leu Ala Arg Arg Ala Gly Ile Leu His Asp Ile

85 90 95Gly Lys Ala Leu Thr Gln Glu Leu Gly Arg Asp His Val Asn Leu Gly

100 105 110Val Glu Val Cys Lys Arg His Lys Glu Asp Pro Val Val Ile Asn Ala

115 120 125Ile Tyr Ala His His Gly His Glu Glu Ile Met Ser Val Glu Cys Ala

130 135 140Ser Val Cys Ala Ala Asp Ala Leu Ser Ala Gly Arg Pro Gly Ala Arg145 150 155 160Arg Lys Ser Asp Glu Glu Tyr Ala Lys Arg Met Gln Ala Leu Glu Glu

165 170 175Ile Ala Leu Glu Phe Asp Gly Val Glu Lys Ala Tyr Ala Met Glu Ser

180 185 190Gly Arg Glu Leu Arg Val Ile Val Lys Set Asn Gln Val Arg Asp Asn

195 200 205Gln Val Pro Ile Ile Ala Arg Lys Ile Ala Lys Arg Ile Glu Glu Ser

210 215 220Thr Gln Tyr Val Gly Glu Val Gly Val Gln Val Val Arg Glu Asn Arg225 230 235 240Phe Lys Thr Thr Ala Thr Leu Ser Asn Asp

245631 (2) SEQ ID NO 668 information

Sequence properties:

(A) length: 804 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...804

(xi) sequence representation: 668 SEQ ID NO: Ser Leu Trp Leu Lys ser Lys Phe Phe Leu Leu Met Gly Val Gly Leu 151015 Leu Ser His Ser Leu Asn Ala Leu Ser Leu Thr Leu Thr Gln Gly Lys

20 25 30Glu Glu Gly Glu Asp Phe Ser Val Leu Thr Leu Arg Asn Asp Lys Ala

35 40 45Phe Ser Cys Ser Tyr Ala Asn Glu Lys Pro Pro Ser Gly Ile Glu Ala

50 55 60Ser Leu Ser Ile Ile His Ala Lys Arg Pro Ile Glu Cys Val lle Asp65 70 75 80Ser Ile Pro Lys Glu Gly Phe Thr Pro Leu Glu Asn Ala Phe Phe Asn

85 90 95Ile Thr Tyr Ser Met Arg Gln Gln Gln Phe Ile Leu His Ile Lys Pro

100105 110Lys Val Met Arg Arg Leu Thr Leu Phe Ser Phe Asp Arg Asp Tyr Lys

115 120 125Lys Ala Ile Pro Leu Phe Val Glu Asn Asp Ala Lys Ala Lys Met Trp

130 135 140Gln Ile Ile Gly Tyr Asp Gln Lys Ile Pro Phe Leu Ser Glu Lys Asp145 150 155 160Asn Ala Gln Lys Gly Leu Asn Phe Pro Ile Ile Ile Lys Asp Ala Gln

165 170 175Thr Pro Ile Ile Gln Glu Leu Asp Val Asn Asn Lys Pro Leu Leu Thr

180 185 190Thr Lys Gly Tyr Asp Leu Asn Ala Tyr Leu Glu Ala Lys Lys Gln Met

195 200 205Asp Ser Gln Ala Tyr Phe Asp Ala Leu Arg Thr Ile Ser Arg Ala Phe

210 215 220Lys Asn Tyr Pro Gln Thr Ile Phe Lys Lys Asp Leu Tyr Leu Leu Glu225 230 235 240Ile Ile Ala Leu Gly Lys Leu Gly Ile Lys Lys Ser Leu Leu Ile Asp

245 250 255Ile Gly Thr Gln Trp Ile Lys Asn Tyr Pro Thr Asp Pro Asn Ile Pro

260 265 270Glu Ala Leu Tyr Tyr Val Ala Lys Ala Leu Asp Glu Asn Asn Asn Tyr

275 280 285Lys Gln Ala Val Arg Tyr Tyr Lys Arg Ile Leu Leu Glu Tyr Lys Asn

290 295 300Ser Arg Tyr Ala Pro Leu Ala Gln Met Arg Leu Ala Ile Glu Ala Ala305 310 315 320Glu Gly Ser Asp Leu Ser Asn Ala Asn Met Leu Phe Lys Glu Ala Phe

325330 335Ser Asn Ala Lys Asp Lys Glu Ser Ala Ser Glu Ile Ala Leu Asn Trp

340 345 350Ala Glu Ala Glu Ile Asn Tyr Gln Asn Phe Asn Asn Ala Lys Tyr Leu

355 360 365Ile Asp Lys Val Val Gln Ser Asn Pro Asp Tyr Leu Ser Met His Ser

370 375 380Glu Leu Ala Leu Glu Leu Leu Lys Leu Leu Lys Lys Asn Gln Met Asn385 390 395 400Glu Ser Ala Ile Glu Ile Ala His Leu Leu Leu Asn Gln Asp Asp Asp

405 410 415Leu Lys Ala Lys Glu Gln Ala Leu Tyr Asp Leu Gly Ala Leu Tyr Ala

420 425 430Arg Ile Lys Asp Phe Lys Asn Ala His Leu Tyr Asn Leu Gln Tyr Leu

435 440 445Gln Asp His Ala Glu Leu Glu Arg Ala Ser Val Val Arg Ala Arg Asp

450 455 460Glu Lys Ala Leu Phe Ser Met Glu Gly Asn Thr Gln Glu Lys Ile Ala465 470 475 480His Tyr Asp Lys Ile Ile Gln Asn Phe Pro Asn Ser Asn Glu Ala Gln

485 490 495Lys Ala Leu Glu Leu Lys Ala Gln Leu Leu Phe Asp Asn Lys Mis Tyr

500 505 510Ala Glu Val Leu Gly Met Gln Lys Asn Leu Pro Lys Asp Ser Pro Leu

515 520 525Ile Gln Lys Thr Leu Asn Ile Leu Ala Lys Thr Pro Leu Glu Asp His

530 535 540Arg Cys Lys Glu Ala Leu Lys Tyr Leu Ser Gln Ile Thr Ala Phe Ala545 550 555560Phe Asn Pro Gln Glu Glu Ile Gln Ala Phe Asp Cys Leu Tyr Phe Ala

565 570 575Ser Leu Lys Glu Lys Ala Gln Ile Ile Ala Leu ASn Ala Leu Lys Ala

580 585 590Ala Lys Thr Pro Ser Glu Lys Leu Thr Trp Leu Tyr Arg Leu Gly Arg

595 600 605Asn Tyr Tyr Arg Leu Gly Asp Phe Lys Asn Ser Thr Leu Ala Ser Lys

610 615 620Asp Ala Leu Ile Leu Ala Gln Ser Leu Asn Lys Lys Glu Phe Tyr Asp625 630 635 640Ile Ala Phe Val Leu Phe Ser Asp Tyr Met Gln Asn Asn Glu Lys Gly

645 650 655Leu Ala Leu Asn Leu Tyr Ala Phe Leu Glu Lys His Phe Lys Asp Asp

660 665 670Lys Arg Met Ala Leu Val Tyr Phe Lys Leu Leu Glu Asn Glu Lys Asp

675 680 685Pro Lys Ser Val Lys Ile Tyr Ala Thr Ser Leu Leu Lys Leu Gln Asp

690 695 700Ala Tyr Lys Asp Tyr Ser Tyr Thr Pro Phe Gly Glu Phe Ala Leu Ile705 710 715 720Asp Ala Tyr Arg Thr Thr Lys Asp Tyr Ser Lys Ala Leu Glu Thr Leu

725 730 735Asp Lys Leu Leu Asn Arg Arg Leu Ser Leu Glu Asp His Gln Lys Ala

740 745 750Leu Tyr Leu Gln Ser Ser Leu Leu Asp Leu Thr Asn Gln Lys Ala Lys

755 760 765Ser Lys Ala Ser Leu Glu Lys Cys Val Gln Leu Lys Gln Lys Asp Gln

770775780Thr Asn Ala Trp Gln Asn Leu Cys Glu Gln Gly Leu Asn Leu Phe Lys 785790795800 Asn Lys GluSer (2) SEQ ID NO:669 information

Sequence properties:

(A) length: 382 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...382

(xi) sequence representation: SEQ ID NO 669: Lys His Pro Asn Arg Phe Phe Phe Lys Arg Ile Glu Arg Thr Ala Leu 151015 Lys Pro Asn Thr Phe Leu Asn Ala Pro Met Gln Lys Pro Gln Asn Lys

20 25 30Pro Ser Ser Ser Gln Gln Ser Pro Gln Asn Phe Ser Tyr Pro Glu Ser

35 40 45Lys Leu Gly Ser Lys Asn Ser Lys Asn Ser Leu Leu Gln Pro Leu Val

50 55 60Thr Pro Ser Lys Val Ser Pro Thr Asn Glu Val Lys Thr Pro Thr Asn65 70 75 80Asp Ala Asn Pro Pro Leu Lys His Ser Ser Gln Asp Gln Glu Asn Asn

85 90 95Leu Phe Val Ala Pro Pro Thr Glu Lys Thr Leu Pro Asn Asn Thr Ser

100 105 110Ser Ala Asp Ala Ser Glu Asn Asn Glu Ser Asn Glu Asn Arg Asp Asn

115 120 125Val Glu Lys Gln Ala Ile Arg Asp Pro Asn Ile Lys Glu Phe Ala Cys

130 135 140Gly Lys Trp Val Tyr Asp Asp Glu Asn Leu Gln Ala Tyr Arg Pro Ser 145 150 155 160Ile Leu Lys Arg Val Asp Lys Asp Lys Glu Ile Thr Thr Asp Ile Thr

165 170 175Pro Cys Asp Tyr Ser Thr Ala Glu Asn Lys Ser Gly Lys Ile Ile Thr

180 185 190Pro Tyr Thr Lys Ile Ser Val His Lys Thr Glu Pro Leu Glu ASp Pro

195 200 205Gln Thr Phe Glu Ala Lys Asn Asn Phe Ala Ile Leu Gln Ala Arg Ser

21C 215 220Ser Thr Glu Lys Cys Lys Arg Ala Arg Ala Arg Lys Asp Gly Thr Thr225 230 235 240Arg Gln Cys Tyr Leu Ile Glu Glu Pro Leu Lys Gln Ala Trp Glu Ser

245 250 255Glu Tyr Glu Ile Thr Thr Gln Leu Val Lys Ala Ile Tyr Glu Arg Pro

260 265 270Lys Gln Asp Asp Gln Val Glu Pro Thr Phe Tyr Glu Thr Ser Glu Leu

275 280 285Ala Tyr Ser Ser Thr Arg Lys Ser Glu Ile Thr Arg Asn Glu Leu Asn

290 295 300Leu Asn Glu Lys Phe Met Glu Phe Val Glu Val Tyr Glu Gly His Tyr305 310 315 320Leu Asn Asp Ile Ile Lys Glu Ser Ser Glu Tyr Lys Glu Trp Val Lys

325 330 335Asn His Val Arg Phe Lys Glu Arg Val Cys Mer Ala Leu Lys Ile Lys

340 345 350Lys Gln Pro Arg Ala Lys Ser Thr Pro LeuSer Ile Glu Asn Ser Arg

355 360 365Val Val Cys Val Lys Lys Gly Asn Tyr Leu Phe Asn Glu Val

370375380 (2) SEQ ID NO:670 information

Sequence properties:

(A) length: 105 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...105

(xi) sequence representation: 670: Thr Lys Lys Leu Asn Asn Thr Leu Phe Asn Lys Gly Leu Ile Ile Phe 151015 Lys Met Phe Lys Lys Ile Ile Phe Leu Cys Val Phe Leu Ile Gly Gly SEQ ID NO

20 25 30Phe Val Ile Pro Pro Leu Glu Ala Met Pro Ile Leu Arg Asn Lys Thr

35 40 45Pro Lys Lys Asn Tyr Gln Glu Ala His Glu Lys Leu Tyr Arg Ser Ile

50 55 60Ile Asn Arg Gln Lys Leu Thr Arg Lys Lys Ser Gly Trp Tyr Phe Leu65 70 75 80Gly Gly Val Gly Ala Val Glu Ala Ile Lys Asp Tyr Gln Gly Lys Glu

85 90 95Met Lys Asp Trp Met Pro Arg Ser Ile

100105 (2) SEQ ID NO 671 message

Sequence properties:

(A) length: 69 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...69

(xi) sequence representation: SEQ ID NO 671: Ser Lys Thr Ser Tyr Cys Asn Ser Tyr Lys Arg Lys Leu Leu Pro Tyr 151015 His Phe Leu Leu Phe Pro Leu Trp Ala Cys Phe His Asn Val Ser Arg

20 25 30Pro Phe Ser Leu Ser His Leu Phe Leu Val Lys Arg Pro Tyr Ser Arg

35 40 45Leu Tyr Leu His Asn Gln Ser Asn His Lys Met Arg His His Ser Ile

505560 Leu Phe Val Ser Phe65(2) SEQ ID NO 672 information

Sequence properties:

(A) length: 458 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...458

(xi) sequence representation: SEQ ID NO 672: Gln AspLys Gly Leu Leu Leu Ser Val Ala Leu Pro Asn Ser Asn Asn 151015 Ala Ser Gln Asn Asn Ile Leu Ser Leu Ser Val Leu His Asn Gln Ile

20 25 30Lys Met Ser Tyr Gly Asn Lys Val Met Asp Phe Thr Pro Pro Thr Leu

35 40 45Gln Asp Tyr Ile Val Gly Ile Gln Gly Gln Ser Ala Leu Asn Gln Ile

50 55 60Glu Ala Val Gly Gly Asn Asn Ala Ile Lys Trp Leu Ser Thr Leu Met65 70 75 80Met Glu Thr Lys Glu Asn Pro Leu Phe Ala Pro Ile Tyr Leu Glu Asn

85 90 95His Ser Leu Asn Glu Ile Leu Gly Val Thr Lys Asp Leu Gln Asn Thr

100 105 110Ala Ser Leu Ile Ser Asn Pro Asn Phe Arg Asn Asn Ala Thr Ser Leu

115 120 125Leu Glu Met Ala Ser Tyr Thr Gln Gln Thr Ser Arg Leu Thr Lys Leu

130 135 140Ser Asp Phe Arg Ala Arg Glu Gly Glu Ser Asn Phe Ser Glu Arg Leu145 150 155 160Leu Glu Leu Lys Asn Lys Arg Phe Ser Asp Pro Asn Pro Ser Glu Val

165 170 175Phe Val Lys Tyr Ser Gln Leu Ser Lys His Pro Asn Asn Leu Trp Ile

180 185 190Gln Gly Val Gly Gly Ala Ser Phe Ile Ser Gly Gly Asn Gly Thr Leu

195 200 205Tyr Gly Leu Asn Val Gly Tyr Asp Ar9 Leu Val Lys Ser Val Ile Leu

210 215 220Gly Gly Tyr Val Ala Tyr Gly Tyr Ser Gly Phe Asn Gly Asn Ile Met225 230235 240Mis Ser Leu Ala Asn Asn Val Asp Val Gly Met Tyr Ala Arg Ala Phe

245 250 255Leu Lys Arg Asn Glu Phe Thr Leu Ser Ala Asn Glu Thr Tyr Gly Gly260 265 270Asn Ala Ser His Ile Asn Ser Ser Asn Ser Leu Leu Ser Val Leu Asn

275 280 285Gln Arg Tyr Asn Tyr Asn Thr Trp Thr Thr Ser Val Asn Gly Asn Tyr

290 295 300Gly Tyr Asp Phe Met Phe Lys Gln Lys Ser Val Val Leu Lys Pro Gln305 310 315 320Val Gly Leu Ser Tyr His Phe Ile Gly Leu Ser Gly Met Lys Gly Lys

325 330 335Met Gln Asn Pro Ala Tyr Gln Gln Phe Val Met His Ser Asn Pro Ser

340 345 350Asn Glu Ser Val Leu Thr Leu Asn Met Gly Leu Glu Ser Arg Lys Tyr

355 360 365Phe Gly Lys Asn Ser Tyr Tyr Phe Val Thr Ala Arg Leu Gly Arg Asp

370 375 380Leu Leu Ile Lys Ala Lys Gly Asp Asn Val Val Arg Phe Val Gly Glu385 390 395 400Asn Thr Leu Leu Tyr Arg Lys Gly Glu Ile Phe Asn Thr Phe Ala Ser

405 410 415Val Ile Thr Gly Gly Glu Met His Leu Trp Arg Leu Met Tyr Val Asn

420 425 430Ala Gly Val Gly Leu Lys Met Gly Leu Gln Tyr Gln Asp Leu Asn Ile

435 440 445Thr Gly Asn Val Gly Met Arg Val Ala Phe

450455 (2) SEQ ID NO 673 message

Sequence properties:

(A) length: 186 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...186

(xi) sequence representation: 673: Pro Phe Glu Ala Leu Asn Phe Tyr Ser Lys Lys Ala Leu Asn Glu Ile 151015 Phe Ala Asn Ala Arg Lys Ile Cys Gly Asn Lys Pro Leu Gly Ala Asn SEQ ID NO

20 25 30Ile Leu Tyr Ala Ile Asn Asp Tyr Gly Arg Val Leu Arg Asp Ser Cys

35 40 45Glu Ala Gly Ala Asn Ile Ile Ile Thr Gly Ala Gly Leu Pro Thr Asn

50 55 60Met Pro Glu Phe Ala Lys Asp Phe Ser Asp Val Ala Leu Ile Pro Ile65 70 75 80Ile Ser Ser Ala Lys Ala Leu Lys Ile Leu Cys Lys Arg Trp Ser Asp

85 90 95Arg Tyr Lys Arg Ile Pro Asp Ala Phe Ile Val Glu Gly Pro Leu Ser

100 105 110Gly Gly His Gln Gly Phe Lys Tyr Glu Asp Cys Phe Lys Glu Glu Phe

115 120 125Gln Leu Glu Asn Leu Val Pro Lys Val Val Glu Ala Ser Lys Glu Trp

130 135 140Gly Asn Ile Pro Ile Ile Ala Ala Gly Gly Ile Trp Asp Arg Lys Asp145 150 155 160Ile Asp Thr Met Leu Ser Leu Gly Ala Ser Gly Val Gln Met Ala Ile

165 170 175Ser Phe Phe Arg His Glu Arg Met Arg Arg

180185 (2) SEQ ID NO 674 information

Sequence properties:

(A) length: 88 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...88

(xi) sequence representation: 674: Ala Ile Arg Leu Arg Leu Ser Ile Arg Gly Leu Ile Lys Arg Ile Glu 151015 Glu Gly Asn Ala Pro Lys Ile Ala Cys Val Ser Asn Cys Val Thr Pro SEQ ID NO

20 25 30Cys Asn Arg Gly Glu Glu Thr Lys Lys Val Gly Tyr Cys Ile Ala Asp

35 40 45Gly Leu Gly Arg Ser Tyr Leu Gly Asn Arg Glu Glu Gly Leu Tyr Phe

50 55 60Thr Gly Ala Asn Gly Tyr Arg Val Asp Lys Ile lle Ser Val His Glu65 70 75 80Leu Ile Lys Glu Leu Thr Glu Gly

85(2) SEQ ID NO 675 information

Sequence properties:

(A) length:284 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...284

(xi) sequence representation: 675: Asn Phe Asn Gln Arg Ala Phe Leu Lys Arg Ala Leu Trp Leu Ile Leu 151015 Gly Leu Phe Tyr Ala Leu Asn Ala Glu Ser Phe Lys Asp Val Leu Thr SEQ ID NO

20 25 30Lys Gly Asp Tyr Thr Phe Phe Asn Lys Lys Val Val Ser Pro Ile Lys

35 40 45Arg Tyr Ala Asp Arg Ser Ala Phe Tyr Leu Gly Leu Gly Tyr Gln Leu

50 55 60Gly Ser Ile Gln His Asn Ser Ser Asn Leu Asn Leu Ser Gln Arg Phe65 70 75 80Asn Lys Ser Gln Ile Ile Phe Ser Asp Ser Leu Ser Pro Val Phe Lys

85 90 95Asn Ser Tyr Val Ser Asn Gly Leu Gly Val Gln Val Gly Tyr Lys Trp

100 105 110Val Gly Lys His Glu Glu Thr Lys Trp Phe Gly Phe Arg Trp Gly Leu

115 120 125Phe Tyr Asp Leu Ser Ala Ser Leu Tyr Gly Ser Gln Glu Ser Gln Ser

130 135 140Ile Ile Ile Ser Thr Tyr Gly Thr Tyr Met Asp Leu Leu Leu Asn Ala145 150 155 160Tyr Asn Gly Asp Lys Phe Phe Ala Gly Phe Asn Leu Gly Ile Ala Phe

165 170 175Ala Gly Val Tyr Asp Arg Leu Ser Asp Ala Leu Leu Tyr Gln Thr Leu

180 185 190Leu Gln Asn Thr Phe Gly Gly Lys Val Asn Leu Asn Gly Phe Gln Phe

195 200 205Leu Val Asp Leu Gly Val Arg Leu Gly Asn Glu His Asn Gln Phe Gly

210 215 220Phe Gly Ile Lys Ile Pro Thr Tyr Tyr Phe Asn His Tyr Tyr Ser Met225 230 235 240Asn Asn Ile Ser Asn Asn Ser Giu Asn Vai Leu Lys Val Leu Arg Phe

245 250 255Leu Glu Tyr Gly Ile Asn Ser Leu Leu Tyr Gln Val Asp Phe Arg Arg

260 265 270Asn Tyr Ser Val Tyr Phe Asn Tyr Thr Tyr Ser Phe

275280 (2) SEQ ID NO 676 information

Sequence properties:

(A) length: 66 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...66

(xi) sequence representation: 676 SEQ ID NO: Lys Met His Thr Ser Phe Phe Gln Ile Pro Leu Asn Phe Gly Val Arg 151015 Val Asn Val Asp Arg His Asn Gly Phe Glu Met Gly Leu Lys Ile Pro

20 25 30Leu Ala Val Asn Ser Phe Tyr Glu Thr His Gly Lys Gly Leu Asn Ala

35 40 45Ser Leu Phe Phe Lys Arg Leu Val Met Phe Asn Val Ser Tyr Val Tyr

505560 Ser Phe65(2) SEQ ID NO:677 information

Sequence properties:

(A) length: 138 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...138

(xi) sequence representation: 677: Ile Lys ArG Ile Ile Lys Ser Asn Ala Ser Leu Asn Gln Leu Asn Thr 151015 Thr Arg Tyr Asn Thr Pro Ser His Leu Phe Phe Lys Lys Gly Val Gly

20 25 30Met Ala Thr Ile Gln Pro Phe Asn His Ser Thr Ile Gln Pro Phe Asn

35 40 45His Ser Thr Ile Gln Pro Phe Asn His Ser Ile Ile Gln Ser Phe Asn

50 55 60His Ser Thr Ile Gln Ala Thr Leu Pro Tyr Phe Tyr Asn Tyr Leu Ser65 70 75 80Phe Tyr Lys Asn Leu Phe Lys Asn Pro Leu Phe Phe Ile Ile Pro Pro

85 90 95Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro

100 105 110Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe lle Asn Pro

115 120 125Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile

130135 (2) information of SEQ ID NO:678

Sequence properties:

(A) length: 193 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...193

(xi) sequence representation: 678: Arg Tyr His His Phe Ser Gly Leu Ser Ser Cys Gly Phe Ser Ala Gln 151015 Cys Gly Cys Gly His Val Ala Ser His Ser Leu Trp His Gln Leu Trp SEQ ID NO

20 25 30Pro Trp Pro Asn Leu Gly Pro Glu His Leu Glu Asn Gly Gly Val Arg

35 40 45Ser Phe Asp Asn Thr Pro Asn Tyr Ser Tyr Ash Thr Gly Ser Gly Thr

50 55 60Thr Thr Thr Thr Cys Asn Gly Ala Ser Asn Val Gly Pro Asn Gly Ile65 70 75 80Leu Ser Ser Ser Glu Tyr Gln Val Leu Asn Thr Ala Tyr Gln Thr Ile

85 90 95Gln Thr Ala Leu Asn Gln Asn GlnGly Gly Gly Met Pro Ala Leu Asn

100 105 110Ser Ser Lys Asn Met Val Val Asn Ile Ash Gln Thr Phe Thr Lys Asn

115 120 125Pro Thr Thr Glu Tyr Thr Tyr Pro Asp Gly Asn Gly Asn Tyr Tyr Ser

130 135 140Gly GIy Ser Ser Ile Pro Ile Gln Leu Lys Ile Ser Ser Val Asn Asp145 150 155 160Ala Glu Asn Leu Leu Gln Gln Ala Ala Thr Ile Ile Asn Val Leu Thr

165 170 175Thr Gln Asn Pro His Val Asn Gly Gly Gly Gly Val Met Gly Val Trp

180185190 Arg (2) SEQ ID NO 679 information

Sequence properties:

(A) length: 418 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...418

(xi) sequence representation: 679: Met Val Val Val Gly Ser Trp Gly Phe Gly Gly Lys Thr Gly Asn Val 151015 Met Asp Ile Phe Gly Asp Ser Phe Asn Ala Ile Asn Glu Met Ile Lys SEQ ID NO

20 25 30Asn Ala Gln Ala Val Leu Glu Lys Thr Gln Gln Leu Asn Ala Asn Glu

35 40 45Asn Thr Gln Ile Thr Gln ProAsp Asn Phe Asn Pro Tyr Thr Ser Lys

50 55 60Asp Thr Gln Phe Ala Gln Glu Met Leu Asn Arg Ala Asn Ala Gln Ala65 70 75 80Glu Ile Leu Ser Leu Ala Gln Gln Val Ala Asp Asn Phe His Ser Ile

85 90 95Gln Gly Pro Ile Gln Gln Asp Leu Glu Glu Cys Thr Ala Gly Ser Ala

100 105 110Gly Val Ile Asn Asp Asn Thr Tyr Gly Ser Gly Cys Ala Phe Val Lys

115 120 125Glu Thr Leu Asn Ser Leu Glu Gln His Thr Ala Tyr Tyr Gly Asn Gln

130 135 140Val Asn Gln Asp Arg Ala Leu Ser Gln Thr Ile Leu Asn Phe Lys Glu145 150 155 160Ala Leu Ser Thr Leu Gly Asn Asp Ser Lys Ala lle Asn Ser Gly Ile

165 170 175Ser Asn Leu Pro Asn Ala Lys Ser Leu Gln Asn Met Thr His Ala Thr

180 185 190Gln Asn Pro Asn Ser Pro Glu Gly Leu Leu Thr Tyr Ser Leu Asp Thr

195 200 205Ser Lys Tyr Asn Gln Leu Gln Thr Val Ala Gln Glu Leu Gly Lys Asn

210 215 220Pro Phe Arg Arg Ile Gly Val Ile Asn Tyr Gln Asn Asn Asn Gly Ala225 230 235 240Met Asn Gly Ile Gly Val Gln Ala Gly Tyr Lys Gln Phe Pha Gly Lys

245 250 255Lys Arg Asn Trp Gly Leu Arg Tyr Tyr Gly Phe Phe Asp Tyr Asn His

260 265 270Ala Tyr Ile Lys Ser Asn Phe Phe Asn Ser Ala SerAsp Val Trp Thr

275 280 285Tyr Gly Val Gly Met Asp Ala Leu Tyr Asn Phe Ile Asn Asp Lys Asn

290 295 300Thr Asn Phe Leu Gly Lys Asn Asn Lys Leu Ser Val Gly Leu Phe Gly305 310 315 320Gly Phe Ala Leu Ala Gly Thr Ser Trp Leu Asn Ser Gln Gln Val Asn

325 330 335Leu Thr Met Met Asn Gly Ile Tyr Asn Ala Asn Val Ser Ala Ser Asn

340 345 350Phe Gln Phe Leu Phe Asp Leu Gly Leu Arg Met Asn Leu Ala Arg Pro

355 360 365Lys Lys Lys Asp Ser Asp His Ala Ala Gln His Gly Met Glu Leu Gly

370 375 380Val Lys Ile Pro Thr Ile Asn Thr Asp Tyr Tyr Set Phe Met GIy Ala385 390 395 400Glu Leu Lys Tyr Arg Arg Leu Tyr Ser Val Tyr Leu Asn Tyr Val Phe

405410415 Ala Tyr (2) SEQ ID NO:680 information

Sequence properties:

(A) length: 163 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...163

(xi) sequence representation: 680:Ala Leu Ser Arg Cys Leu Ser Asp Arg Phe Asn Gln Tyr Pro Ala Leu 151015 Gln Lys Thr Glu His His Phe Val Asp Phe Leu Asn GIn Asp Lys His SEQ ID NO

20 25 30Tyr Ala Ile Ile Gln Arg Ala Asp Lys Ser Ile Ser Ser Asn Glu Ala

35 40 45Leu Ala Arg Ser Leu Ile Gly Ala Tyr Val Leu Asn Arg Glu Ser Ile

50 55 60Asn Arg Ile Asp Asp Lys Ser Arg Tyr Glu Leu Val Arg Leu Gln Ser65 70 75 80Ser Ser Lys Val Trp Gln Arg Phe Glu Asp Leu Ile Lys Ala Gln Asn

85 90 95Ser Ile Tyr Val Gln Ser His Leu Glu Arg Glu Val His Ile Val Asn

100 105 110Ile Ala Ile Tyr Gln Gln Asp Asn Asn Pro Ile Ala Ser Val Ser Ile

115 120 125Ala Ala Lys Leu Leu Asn Glu Asn Lys Leu Val Tyr Glu Lys Arg Tyr

130135140 Lys Ile Val Leu Ser Tyr Leu Phe Asp Thr Pro Asp Phe Asg Tyr Ala 145150155160 Ser Met Pro (2) SEQ ID NO:681 information

Sequence properties:

(A) length: 194 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...194

(xi) sequence representation: SEQ ID NO 681: Ser Phe Lys Lys Asn Glu Arg Leu Leu Leu Leu Val Ser Arg Phe Leu 151015 Asn Ala Ile Asp Pro Phe Asn Leu Gly Val Leu Leu Ser Arg Phe Gln

20 25 30Ile Lys Asn Gly Cys Ile Tyr Gly Val Cys Ser Tyr Lys Val Ser Lys

35 40 45Phe Thr Pro Gly Tyr Glu Glu Ser Lys Ala Arg Val Leu Asn Ala Leu

50 55 60Asn Ile Leu Ser Lys His Gln Ile Trp Gln Ser Asn Gln Glu Ser Val65 70 75 80Thr Lys Val Lys Gly Thr Phe Val Phe Ile Leu Glu Asn Asp Leu His

85 90 95Leu Asp Glu Asn Ser Phe Tyr Lys Lys Leu Leu Asn Leu Ile Ile Asp

100 105 110Asn Asp Phe Phe Asn Arg Ser His Leu Val Thr Pro Ser Asn Gly Thr

115 120 125Asn Ser His Pro Glu Leu His Arg Ser Ile Thr Pro Arg Glu Ala Ala

130 135 140Arg Ile Gln Ser Phe Ser Asp Asp Tyr Ile Phe Tyr Gly Asn Lys Thr145 150 155 160Ser Val Cys Lys Gln Ile Gly Asn Ala Val Pro Pro Leu Leu Ala Leu

165 170 175Ala Leu Gly Lys Ala Ile Leu Lys Ser Ala Arg Asn Asp Thr Asn Pro

180185190 Ser Arg (2) SEQ ID NO:682 information

Sequence properties:

(A) length: 165 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...165

(xi) sequence representation: SEQ ID NO. 682: Met Gln Asp Asn Leu Val Ser Val Ile Glu Lys Gln Thr Asn Lys Lys 151015 Val Arg Met Leu Glu Ile Lys Pro Leu Lys Ser Ser Gln Asp Leu Lys

20 25 30Met Val Val Ile Glu Asp Pro ASp Thr Lys Tyr Asn Ile Pro Leu Val

35 40 45Val Ser Lys Asp Gly Asn Ser Val Ile Gly Leu Ser Asn Ile Phe Phe

50 55 60Ser Asn Lys Ser Asp Asp Val Lys Leu Val Ala Glu Thr Asn Gln Lys65 70 75 80Ile Gln Ala Leu Asn Ala Thr Gln Gln Asn Ser Ala Lys Leu Asn Ala

85 90 95Ile Phe Asn Glu Ile Pro Ala Asp Tyr Ala Ile Glu Leu Pro Ser Thr

100 105 110Asn Ala Glu Asn Lys Asp Lys Ile Leu Tyr Ile Val Ser Asp Pro Met

115 120 125Cys Pro His Cys Gln Lys Glu Leu Thr Lys Leu Arg Asp His Leu Lys

130 135 140Glu Asn Thr Val Arg Met Val Val Val Gly Trp Leu Glu Ala Ile Arg145 150 155 160Leu Lys Lys Arg Leu

165(2) SEQ ID NO 683 information

Sequence properties:

(A) length: 115 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...115

(xi) sequence representation: 683 ID NO: Thr Gly Ala Ile Met Leu Ser Ser Asn Asp Leu Phe Met Val Val Leu 151015 Gly Ala Ile Leu Leu Val Leu Val Cys Leu Val Gly Tyr Leu Tyr Leu

20 25 30Lys Glu Lys Glu Phe Tyr His Lys Met Arg Arg Leu Glu Lys Thr Leu

35 40 45Asp Glu Ser Tyr Gln Glu Asn Tyr Leu Tyr Ser Lys Arg Leu Arg Glu50 55 60Leu Glu Gly Arg Leu Glu Gly Leu Ser Leu Glu Lys Ser Ala Lys Glu65 70 75 80Asp Ser Ser Leu Lys Thr Thr Leu Ser His Leu Tyr Asn Gln Leu Gln

85 90 95Glu Ile Gln Lys Ser Met Asp Lys Glu Arg Asp Tyr Leu Glu Glu Lys

100 105 110Ile Ile Thr

115(2) SEQ ID NO 684 information

Sequence properties:

(A) length: 324 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...324

(xi) sequence representation: SEQ ID NO 684 Glu Arg Lys Lys Met Asn Thr Asn Leu Lys Lys Ala Leu Phe Leu Thr 151015 Thr Leu Gly Tyr Leu Gln Ala Asn Glu Gly Phe Leu Ala lle Met Pro

20 25 30Asp Glu Asn Lys Gln Glu Asp Ile Ser Gln Glu Gln Lys Leu Glu His

35 40 45Lys Met Glu Gln Lys Ile Ala Pro Gln Asn Thr Leu Lys Lys Gln Gln

50 55 60Ser Ala Pro Leu Gln Ser Ala Glu Leu Leu Gln Ser Gln Val Lys Arg65 70 75 80Glu Val Lys Glu Gln Lys Lys Ser Gln Lys His Leu Val Ala Met Gln

85 90 95Thr Lys Asn Gly Phe Phe Leu Gly Ser Glu Ile Ala Ile Thr Gly Thr

100 105 110Ser Leu Lys Gln Ser Leu Ser Leu Ile Ser Asn Ala Thr Asp Asp Leu

115 120 125Leu Thr Tyr Ser Lys Thr Ser Lys Asn Ala Asn Phe Asn Met Gly Leu

130 135 140Leu Ile Gly Tyr Gln His Tyr Phe Gly Ala Ser Lys Arg His Gly Ile145 150 155 160Lys Ile Ser Ser His Leu Tyr Gly Gly Thr Pro Ser Asp Val Ser Thr

165 170 175Asp Ile Lys Ile Tyr Lys Ser Lys Val Ser Thr Asn Tyr Thr Pro Leu

180 185 190Asn Phe Gly Ile Asp Val Lys Tyr Leu Phe Asp Phe Leu Asn Val Ile

195 200 205Lys Lys Asn Arg His Thr Leu Gly Leu Ser Val Gly Phe Gly Trp Arg

210 215 220Met Gln Tyr Tyr Phe Ala Lys Ile Asp Pro Ile Lys Thr Ser His Ser225 230 235 240Glu Phe Ile Thr Asn Lys Pro Lys Asp Ile Phe Asn His Gly Phe Tyr

245 250 255Pro Thr Ile Gly Leu His Tyr Tyr Leu Asn His His Gln Phe Glu Val

260 265 270Asn Tyr Arg Phe Gly Gly Ala Ile Asn Tyr Gln Ser Val Val Pro Ser

275 280 285Lys Ile Val Val Gln Asn Gly Asn Phe Lys Gly Glu Val Leu Phe Ser

290295300 Asn Phe Leu Thr Lys Ala Thr Asn Ser Ser Tyr Ile Ala Phe Asn Tyr 305310315320 Ala Tyr Leu Phe (2) SEQ ID NO 685 information

Sequence properties:

(A) length: 137 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...137

(xi) sequence representation: 685: Ala Asn Glu LysMet Glu Leu Ile Lys Lys Leu Glu Lys Glu Ser Glu 151015 Val Leu Lys Lys Asp Leu Gln Gln His Ser Asn Glu Leu Phe Lys Met SEQ ID NO

20 25 30Leu Ile Ile Asp Asn Glu Asp Leu Phe Lys Glu Gln Phe Glu Ile Met

35 40 45Phe Lys Ala Trp Val Glu Ile Val Lys Met Met Phe Glu Leu Thr Lys

50 55 60Lys Thr Lys Phe Asp Gly Glu Met Ile Gly Tyr Thr Glu Glu Leu Leu65 70 75 80Thr Phe Leu Val Arg Asp Phe Phe Asn Gly Ile Phe Lys Ser Lys val

85 90 95Ile Pro Lys Met Pro Ile Phe Cys Gly Asp Val Lys Cys Glu Asp Phe

100 105 110Asn Ala Leu Arg Ser Leu Val Tyr Leu Ser Val Leu Glu Leu Glu Glu

115 120 125Thr Ile Asn Pro Asn Lys Ile Pro Phe

130135 (2) SEQ ID NO 686 information

Sequence properties:

(A) length: 227 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...227

(xi) sequence representation: SEQ ID NO 686: Asn Lys Glu Asn Asn Ile Thr Ile Cys ValAla Asn Glu Lys Gly Gly 151015 Ser Gly Lys Ser Thr Leu Cys Leu Asn Leu Ala Val Gln Leu Leu Lys

20 25 30Asp Asn Lys Glu Val Val Val Leu Asp Thr Asp Ser Gln Lys Ser Met

35 40 45Glu Thr Phe Ala Thr Ile Arg Ala Glu Lys Glu Arg Pro Thr Phe Ser

50 55 60Leu Phe Asn Arg Ser Ser Gly Phe Ser Asp Thr Leu Lys Gln Met Val65 70 75 80Ser Lys Tyr Glu Asn Ile Leu Ile Asp Thr Lys Gly Glu Tyr Ser Lys

85 90 95Glu Thr Gln Lys Ala Met Leu Leu Ser Asn Ile Val Leu Val Pro Thr

100 105 110Thr Pro Ser Gln Leu Asp Thr Glu Val Leu Ala Asn Met Leu Glu Arg

115 120 125Ile Glu Gln Leu Gln Glu Leu Asn Glu Asn Leu Arg Ala Leu Ile Val

130 135 140Ile Asn Arg Met Pro Thr Ile Pro Thr Leu Lys Glu Arg Gln Ala Leu145 150 155 160Ile Glu Phe Ile Lys Glu Asn Asn Pro Ser Asp Arg Ile Thr Leu Leu

165 170 175Glu Ser Ser Leu Ser Glu Arg Ile Val Tyr Lys Arg Ser Val Ser Glu

180 185 190Gly Leu Gly Val Ile Glu Tyr Ser Asp Lys Lys Ala Ile Asn Glu Trp

195 200 205Val Asn Phe Tyr Asn Glu Leu Lys Ser His Leu Glu Lys Glu Lys I1e

210215220 His Ala Phe225(2) SEQ ID NO:687 information

Sequence properties:

(A) length: 105 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...105

(xi) sequence representation: 687 SEQ ID NO: Arg Ser Thr Thr Leu Ile Tyr Phe Asn Phe Lys Glu Pro Met Met Ser 151015 Asp Glu Ile Thr Gln Glu Asn Glu Leu Glu Ile Asn Ser Asn Asn Gln

20 25 30Asn Gln Glu Pro Lys Glu Val Glu Lys Met Pro Leu Asn Asn Ile Gln

35 40 45Lys Ala Lys Lys Leu Lys Asn His Ala Asn Leu Ile Val Arg Arg Thr

50 55 60Asp Glu Leu Asp Lys Val Ile Asn Lys Arg Glu Ser Leu Gln Arg Glu65 70 75 80Phe Lys Arg Arg Ile Lys His Leu Asp Asn Lys Ile Glu Thr Leu Ser

85 90 95Asn Asn Ile Glu Glu Leu Lys Arg Lys

100105 (2) SEQ ID NO 688 message

Sequence properties:

(A) length: 173 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...173

(xi) sequence representation: SEQ ID NO 688 Ser Met Lys Lys Tyr Gln Asn Lys Arg Lys Leu Gly Lys Arg Ile Asn 151015 Cys Phe Ile Ser Asn Glu Cys Lys Asp Ile Leu Glu Asn Tyr Leu Lys

20 25 30Val Lys Lys Ile Ser Val Thr Glu Cys Ile Glu Ser Leu Leu Leu Ala

35 40 45Leu Asp Pro Ser Lys Glu Thr Leu Arg Ala Arg Asp Phe Tyr Glu Ser

50 55 60Leu Phe Lys Val Ile Ser Leu Asn Gln His Val Tyr Lys Glu Leu Met65 70 75 80Ala Asn Gly Asn Asn Ile Asn Gln Ile Ala Lys Asn Thr Asn Ile Ala

85 90 95Ile Lys Tyr Asn Lys Pro Phe Tyr Leu Gln Asn Leu Ala Phe Leu Glu

100 105 110Glu Ile Phe Lys Val Met Asp Thr Leu Asn Lys Asn Val Glu Glu Cys

115 120 125Lys Lys Ile Ser Leu Glu Leu Leu Leu Gln Ile Tyr Lys Glu Gln Lys

130 135 140Ser Gln Thr Glu Phe Asn Ala Ile Ser Lys Ile Leu Asn Ala Leu Asn145 150 155 160Glu Lys Gln Ser Thr Thr Glu Pro Lys Lys Asp Asn Ala

165170 (2) SEQ ID NO:689 information

Sequence properties:

(A) length: 109 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...109

(xi) sequence representation: 689 SEQ ID NO: Lys Ser Pro Tyr Arg His Ser Ile Ser Ser Gln Val Ser Val Glu Asn 151015 Asp Glu Glu Ile Ile Glu Val Glu Lys Gly Glu Asn Gln Gly Ala Phe

20 25 30Ser Tyr Phe Leu Gly Gly Pro Thr Cys Leu Ala Gly Asp Phe Met Gly

35 40 45Ser Phe Ser Phe Glu Thr Pro Leu Lys Arg Gly Asp Lys Ile Val Phe

50 55 60Gln Asp Met Leu His Tyr Thr Ile Val Lys Asn Asn Ser Phe Asn Gly65 70 75 80Val Pro Leu Pro Ser Leu Ala Lys Ile Asp Ser Gln Gly Phe Lys Ile

85 90 95Leu Lys Ser Phe Ser Tyr Glu Asp Tyr Lys Asn Arg Asn

100105 (2) SEQ ID NO:690 information

Sequence properties:

(A) length: 133 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism:helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...133

(xi) sequence representation: 690 of SEQ ID NO:690: Ala Leu Glu Lys Asn Gly Thr Ala Thr Ala Asn Ser Thr Ser Ser Thr 151015 Ser Gly Ala Thr Gly Ser Asp Gly Gln Thr Tyr Ser Gln Gln Ala Ile

20 25 30Gln Tyr Leu Gln Gly Gln Gln Asn Ile Leu Asn Asn Ala Ala Asn Leu

35 40 45Leu Lys Gln Asp Glu Leu Leu Leu Glu Ala Phe Asn Ser Ala Val Ala

50 55 60Ala Asn Ile Gly Asn Lys Glu Phe Asn Ser Ala Ala Phe Thr Gly Leu65 70 75 80Val Gln Gly Ile Ile Asp Gln Ser Gln Leu Val Tyr Asn Glu Leu Thr

85 90 95Lys Asn Thr Ile Ser Gly Ser Ala Val Asn Asn Ala Gly Ile Asn Ser

100 105 110Asn Gln Ala Asn Ala Cys Lys Gly Val Leu Val Ser Ser Leu Thr Leu

115 120 125Phe Thr Thr Cys Lys

130(2) SEQ ID NO 691 information

Sequence properties:

(A) length: 84 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...84

(xi) sequence representation: 691: Leu Ile Lys Glu Ala Met Ile Pro Val Phe Gly Ser Glu Thr Gly Ile 151015 Tyr Asn His Lys Glu Gln Asn Phe Lys Gly Lys Gly Arg Phe Ile Leu SEQ ID NO

20 25 30Thr Ser Lys Asp Ser Lys Val Glu Gly Leu Asp IIe Ser Tyr Ser His

354045 Ala Leu Ala Ile Ile Glu Ala Gln Ser Ile Gln Ala Asn Leu Phe Leu 505560 Asp Glu lle Lys Gln Ser Gln Lys Glu Lys Lys Lys Phe Pro Thr Phe 65707580 Lys Gly Gly Phe (2) SEQ ID NO:692 information

Sequence properties:

(A) length: 161 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feattre

(B) Position: 1...161

(xi) sequence representation: SEQ ID NO 692: Pro Phe Leu Lys Lys Asn Lys Phe Leu Gln Ile Cys Gln Tyr Phe Ser 151015 Ala His Phe Lys Gln Val Leu Lys Asn Glu Lys Pro Leu Val Tyr Tyr

20 25 30Gly Val Leu Lys Ala Lys Ala Pro Asn Trp Ala Leu Trp Val Tyr Glu

35 40 45Lys Pro Leu Lys Lys Glu Ile Tyr Met Asn Asp Lys Glu Val Val Val

5055 60Tyr Glu Pro Asn Leu Phe Gln Ala Thr Ile Thr Pro Leu Lys Asp Lys65 70 75 80Thr Asp Phe Phe Thr Ile Leu Lys Gln Leu Lys Lys Gln Thr Asp Gly

85 90 95Ser Phe Lys Thr Thr Ile Asn Lys Thr Thr Tyr Arg Leu Val Phe Lys

100 105 110Asp Gly Lys Pro Phe ser Leu Glu Phe Lys Asp Asp Met Asn Asn Leu

115 120 125Val Thr Ile Thr Phe Ser Gln Ala Glu Ile Asn Pro Lys Ile Pro Asn

130135140 Glu Ile Phe Val Phe Asn Pro Lys Asp Glu Asn Ile Asp Ile Val Arg 145150155160 Gln (2) SEQ ID NO:693 information

Sequence properties:

(A) length: 71 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...71

(xi) sequence representation: 693: Pro Ser Phe Leu Lys Glu Lys Phe Asp Phe Phe Lys Gly Lys Asn Phs 151015 Lys Ile Val Tyr Cys Ile Gly Glu Asp Leu Thr Thr Arg Glu Lys Gly SEQ ID NO

20 25 30Phe Arg Ala Val Lys Glu Phe Leu Ser Glu Gln Leu Glu Asn Ile Asp

35 40 45Leu Asn Tyr Ser AsnLeu Ile Val Ala Tyr Glu Pro Ile Trp Ala Ile

505560 Gly Thr Lys Lys Ala Arg Phe 6570 (2) SEQ ID NO:694 information

Sequence properties:

(A) length: 155 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...155

(xi) sequence representation: 694: Arg Asp Val Arg Phe His Val Arg Asp Leu Val Arg Gln Leu Lys Gly 151015 Lys His Leu Ile Glu Val Ser Asp Val Ile Asn Asp Thr Thr Gln Pro SEQ ID NO

20 25 30Asn Leu Asp Met Asn Leu Leu Thr Thr Glu Ile Ala Arg Gln Leu Arg

35 40 45Leu Arg Ser Asn Gly Arg Phe Asn Ile Thr Arg Ala Ser Gly Gly Ser

50 55 60Gly Ile Glu Ala Asp Ser Arg Met Val Lys Gln Arg Glu Lys Glu Arg65 70 75 80Glu Ser Glu Glu Tyr Asn Gln Asp Thr Thr Val Glu Lys Gly Thr Leu

85 90 95Lys Ala Ala Asp Leu Ser Leu Ser Gly Lys Val Ser Ser Ile Ala Ale

100 105 110Ser Ile Ser Ser Ser Arg Gln Arg Leu Asp Tyr Asp Phe Thr Leu Ser

115 120125Leu Thr Asn Arg Lys Thr Gly Glu Glu Val Trp Ser Asp Val Lys Pro

130135140 Ile Val Lys Asn Ala Ser Asn Lys Arg Met Phe 145150155 (2) SEQ ID NO 695 information

Sequence properties:

(A) length: 219 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...219

(xi) sequence representation: SEQ ID NO 695: Ile Lys Ser Val Leu Gly Leu Ile Leu Ile Gln Gln Asn Phe Lys Thr 151015 Leu Lys Glu Leu Tyr Met Leu Val Thr Lys Leu Ala Pro Asp Phe Lys

20 25 30Ala Pro Ala Val Leu Gly Asn Asn Glu Val Asp Glu His Phe Glu Leu

35 40 45Ser Lys Asn Leu Gly Lys Asn Gly Val Ile Leu Phe Phe Trp Pro Lys

50 55 60Asp Phe Thr Phe Val Cys Pro Thr Glu Ile Ile Ala Phe Asp Lys Arg65 70 75 80Val Lys Asp Phe His Glu Lys Gly Phe Asn Val Ile Gly Val Ser Ile

85 90 95Asp Ser Glu Gln Val His Phe Ala Trp Lys Asn Thr Pro Val Glu Lys

100 105 110Gly Gly Ile Gly Gln Val Ser Phe Pro Met Val Ala Asp Ile Thr Lys

115 120 125Ser Ile Ser Arg Asp Tyr Asp Val Leu Phe Glu Glu Ala Ile Ala Leu

130 135 140Arg Gly Ala Phe Leu Ile Asp Lys Asn Met Lys Val Arg His Ala Val145 150 155 160Ile Asn Asp Leu Pro Leu Gly Arg Asn Ala Asp Glu Met Leu Arg Met

165 170 175Val Asp Ala Leu Leu His Phe Glu Glu His Gly Glu Val Cys Pro Ala

180 185 190Gly Trp Arg Lys Gly Asp Lys Gly Met Lys Ala Thr His Gln Gly Val

195 200 205Ala Glu Tyr Leu Lys Glu Asn Ser Ile Lys Leu

210215 (2) SEQ ID NO 696 message

Sequence properties:

(A) length: 113 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...113

(xi) sequence representation: SEQ ID NO:696: Gly Val Ile Met Glu His His Lys Ala His Thr Thr Ile Gln Ala Leu 151015 Gln Ala Lys Arg Lys Arg Leu Leu Thr Glu Leu Ala Glu Leu Glu Ala

20 25 30Glu Ile Lys Val Ser Ser Glu Arg Arg Ser Ser Phe Asn Val Ser Leu

35 4045Ser Pro Ser Leu Leu Ala Glu Ile Glu Glu Ile Glu Tyr Glu Glu Lys

50 55 60Met Ser Lys Glu Arg Arg Ile His His Asn Leu Leu Leu Ser Pro Ser65 70 75 80Phe Met Ala Lys Val Asp Glu Tyr Met Lys Glu Lys Gly Phe Pro Asn

85 90 95Arg Ser Leu Leu Phe Glu Lys Ala Leu Glu Phe Tyr Met Leu Lys His

100105110 Pro (2) SEQ ID NO:697 information

Sequence properties:

(A) length: 187 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...187

(xi) sequence representation: SEQ ID NO:697: Gly Phe Val Cys Gly Ser Val Leu Phe Gln Leu Gly Val Phe Met Gly 151015 Leu Lys Asn Lys Ile Lys Gly Phe Val Lys Glu Arg Met Pro Phe Val

20 25 30Met Arg Cys Val Arg Gly Leu Lys Gly Ala Lys Asp Thr His Glu ASn

35 40 45Ala His Asp Arg Asp Ala Tyr Cys Gly Ile Asn Arg Glu Ile Lys Glu

50 55 60Met Leu Glu Ala Lys Lys Leu His Phe Leu Gln Glu Lys Ala Leu Phe65 70 75 80Asn His Asp HisGln Glu Ser Val Phe Leu Ala Ile Ala Ser Leu Asn

85 90 95Asn Glu Ser Phe Ile Glu Tyr Asn Lys Ser Ile Tyr Lys Asn Ser Ser

100 105 110Leu Asn Tyr Asn Tyr Gly Gly His Leu Glu Asp Arg Val Ile His Pro

115 120 125Thr Leu Thr Leu Pro Asn Pro Thr His Ser Gly Tyr Phe Asp Tyr Asp

130 135 140Lys Lys Ser Gln Asn Pro Lys Ser Pro Leu Asn Pro Trp Ala Phe Ile145 150 155 160Arg Val Lys Asn Glu Ile Val Thr Leu Glu Glu Ser Leu Phe Ser Met

165 170 175Leu Pro Ala Val Gln Arg Gly Gly His Trp Phe

180185 (2) SEQ ID NO:698 information

Sequence properties:

(A) length: 230 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...230

(xi) sequence representation: SEQ ID NO:698: Lys Arg Val Cys Phe Leu Cys Phe Leu Pro Phe Lys Gly Gly Val Ile 151015 Gly Phe Asn Asp Cys Asp Asp Gly Ser Lys Glu Val Val Leu Glu Phe

20 25 30Cys Lys Lys Phe Pro Ser Phe Ile Pro Ile Ser Tyr Pro Tyr Glu Val

35 40 45Ile Leu Lys Asp Cys Pro Ser Leu Trp His Gln Leu Tyr His Tyr Cys

50 55 60Asn Tyr Thr Leu Ser Phe Ile Pro Lys Asn Glu Trp Val Val Lys Ile65 70 75 80Asp Cys Asp His Ile Tyr Asp Ala Lys Lys Leu Tyr Lys Ser Phe Tyr

85 90 95Ile Pro Lys Asn Ile Lys Glu Val Val Met Tyr Ser Arg Ile Asn Phe

100 105 110Val Val Arg Asp Phe Glu Val Phe Val Arg Asn Asp Gly Asp Phe Gly

115 120 125Phe Leu Asp Ala Trp Gly Asp His Trp Leu Leu Tyr Asn Asp Cys Glu

130 135 140Pro Phe Glu Ile Trp Arg Tyr Asn Asp Glu Ser Tyr Glu Val Leu Lys145 150 155 160Leu Lys Asp Lys His His Ile Lys Asp Lys Glu Met Val Gln Trp His

165 170 l75Phe Pro Leu Ala Lys Lys Arg Arg Asn Ala Ile Val Tyr Asp Asp Leu

180 185 190Ile Pro Leu Glu Glu Phe Lys Lys Arg His Ala Asp Leu Ile Gly Thr

195 200 205Arg Ile Glu Glu Ser Met Leu Asp Glu Lys Arg Ile Leu Glu Val Tyr

210215220 Gln Lys Phe Arg Leu Pro 225230 (2) SEQ ID NO:699 message

Sequence properties:

(A) length: 86 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...86

(xi) sequence representation: SEQ ID NO:699: Leu Ser Leu Asn Lys Lys Met Met Phe Glu Leu Thr Lys Lys Thr Lys 151015 Phe Asp Gly Glu Met Ile Gly Tyr Thr Glu Glu Leu Leu Thr Phe Leu

20 25 30Val Arg Asp Phe Phe Asn Gly Ile Phe Lys Ser Lys Val Ile Pro Lys

35 40 45Met Pro Ile Phe Cys Gly Asp Val Lys Cys Glu Asp Phe Asn Ala Leu

50 55 60Arg Ser Leu Val Tyr Leu Ser Val Leu Glu Leu Glu Glu Thr Ile Asn65 70 75 80Pro Asn Lys Ile Pro Phe

85(2) SEQ ID NO 700 message

Sequence properties:

(A) length: 164 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...164

(xi) sequence representation: 700: Phe Ser ArgLys Thr Asp Lys Asn Ala Gln Lys Asp Glu Gln Lys Asn 151015 Glu Gln Glu Glu Gln Arg Arg Leu Arg Glu Gln Gln Arg Leu Lys Gln SEQ ID NO

20 25 30Asn Gln Glu Asn Gln Glu Met Leu Lys Gly Leu Gln Gln Asn Leu Asn

35 40 45Gln Phe Thr Gln Lys Leu Glu Ser Val Lys Asn Lys Thr Leu Asp Leu

50 55 60Gln Ile Pro Lys Gln Asp Gly Val Asp Glu Lys Ala Tyr Gln Glu Trp65 70 75 80Tyr Ala Gln Ile Tyr Gln Ile Leu Tyr Lys Gly Trp Arg Gly Val Phe

85 90 95Tyr His Lys Ala Ser Val Ser Val Leu Ile Me5 Ile Thr Lys Asp Gly

100 105 110Glu Phe Asp Tyr Thr Ile Leu Ser Tyr Ser Asp Phe Lys Asp Tyr Asn

115 120 125Lys Ser Val Met Thr Leu Leu Asp Asp Leu Lys Lys Val Asp Phe Pro

130135140 Pro Tyr Pro Gly Gly Asn Met Ile Ser Ile Lys Val Asn Phe Thr Thr 145150155160 Lys Glu Gln (2) SEQ ID NO:701 information

Sequence properties:

(A) length: 68 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...68

(xi) sequence representation: 701 SEQ ID NO: Arg Ala Arg Leu Leu Arg Arg Lys Asn His Tyr Leu Glu Asn Lys Phe 151015 Lys Asp Met Gly His Tyr Ala Ala Ser Asp Glu Val Asn Glu Lys Gln

20 25 30Val Leu Lys Met Tyr Gln Glu Gly Tyr Ser Val Asp Ser Ile Ser Lys

35 40 45Glu Phe Lys Val Ser Lys Gly Glu Val Glu Phe Ile Leu Asn Met Ala

505560 Gly Leu Lys Trp65(2) SEQ ID NO:702 information

Sequence properties:

(A) length: 97 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...97

(xi) sequence representation: SEQ ID NO 702: Thr Lys Leu Asp Thr Ile Ser Leu Lys Arg Ile Gln Met Glu Lys Leu 151015 Pro Lys Lys Arg Val Ser Lys Thr Lys Ser Gln Lys Leu Ile His Ser

20 25 30Leu Thr Thr Gln Lys Asn Arg Ala Phe Leu Lys Lys Ile Set Ala Asn

35 40 45Glu Mer Leu Leu Glu Leu Glu Lys Gly Ala Phe Lys Lys Asn Glu Ala

50 55 60Tyr Phe Ile Ser Asp Glu Glu Asp Lys Asn Tyr Val Leu Val Pro Asp65 70 75 80Asn Val Ile Ser Leu Leu Ala Glu Asn Ala Arg Lys Ala Pne Glu Ala

859095 Arg (2) SEQ ID NO:703 information

Sequence properties:

(A) length: 272 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...272

(xi) sequence representation: SEQ ID NO 703: Arg Ser Ile Lys Met Lys Gln Ser Leu Arg Glu Gln Lys Leu Leu Lys 151015 Ile Leu Glu Asn Asp Val Leu Thr Ile Leu Asp Ser Phe Ser Asn Tyr

20 25 30Leu Phe Glu Leu Arg Glu Glu Leu Asp Phe Ile Glu Glu Glu Met Glu

35 40 45Gly Glu Ile Thr Glu Gln Asn Leu Thr Ala Leu Tyr Asp Phe Ser Asn

50 55 60Phe Leu Glu Asp His Val Asn Val Phe Tyr Glu Asn Val Leu Asn Ile65 70 75 80Asp Asp Val Lys Thr Glu His Leu Tyr Ser Gly Leu Ile Asp Ser Leu

85 90 95Asn Ala Asn Leu His Phe Val Lys Ser Phe Leu Ser Asn Gln Asp Leu

100 105 110Asp Phe Arg Phe Phe Lys Glu Ile Asn Asp Gly Gln Asp Pro Gln Lys

115 120 125Thr Leu SerArg Leu Ile Pro Leu Gln Ser Gly Lys Asn Asp Ala Ser

130 135 140Ser Phe Lys Ala Asn Asn Ser Phe Val Ser Leu Val Tyr Val Tyr Ala145 150 155 160Tyr Phe Met Leu Glu Thr Ile Arg Gln Ser Tyr Arg Ile Leu Arg Leu

165 170 175Leu Glu Lys Pro Ile Asn Asn Asn Ile Ser Glu Asp Met Gln Ser Asp

180 185 190Ile Glu Asn Phe Phe Val Gln Ala Asn Phe Leu Glu Tyr Tyr Val Gln

195 200 205Asn Lys Ile Tyr Pro Thr Asn His Ala Tyr Asp Phe Thr His Leu Ile

210 215 220Met Asp Ser Ile Ile Pro Asn Trp Ile Gln Ile Asp Met Ser Val Glu225 230 235 240Ala Lys Lys Lys Glu Leu Phe Glu Lys Tyr Phe Gln Asn Ile Asp Glu

245 250 255Val Thr Asn Lys Met Leu Ala Gln Glu Asn Gln Asn Lys Asn Ser Asp

260265270 (2) SEQ ID NO 704 information

Sequence properties:

(A) length: 229 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...229

(xi) sequence representation: 704: Val Lys Gly Glu Lys Asn Ala Trp Tyr Leu Gly lle Ser Tyr Gln Val 151015 Gly Gln Ala Ser Gln Ser Val Lys Asn Pro Pro Lys Ser Ser Glu Phe

20 25 30Asn Tyr Pro Lys Phe Pro Val Gly Lys Thr Asp Tyr Leu Ala Val Met

35 40 45Gln Gly Leu Gly Leu Thr Val Gly Tyr Lys Gln Phe Phe Gly Glu Lys

50 55 60Arg Trp Phe Gly Ala Arg Tyr Tyr Gly Phe Met Asp Tyr Gly His Ala65 70 75 80Val Phe Gly Ala Asn Ala Leu Thr Ser Asp Asn Gly Gly Val Cys Lys

85 90 95Leu Asn Glu Pro Cys Ala Thr Lys Val Gly Thr Met Gly Asn Leu Ser

100 105 110Asp Met Phe Thr Tyr Gly Val Gly Ile Asp Thr Leu Tyr Asn Val Ile

115 120 125Asn Lys Glu Asp Ala Ser Phe Gly Phe Phe Phe Gly Ala Gln Ile Ala

130 135 140Gly Asn Ser Trp Gly Asn Thr Thr Gly Ala Phe Leu Glu Thr Lys Ser145 150 155 160Pro Tyr Lys His Thr Ser Tyr Ser Leu Asp Pro Ala Ile Phe Gln Phe

165 170 175Leu Phe Asn Leu Gly Ile Ar9 Thr His Ile Gly Gln His Gln Glu Phe

180 185 190Asp Phe Gly Val Lys Ile Pro Thr Ile Asn Val Tyr Tyr Phe Asn His

195 200 205Gly Asn Leu Ser Phe Thr Tyr Arg Arg Gln Tyr Ser Leu Tyr Val Gly

210215220 Tyr Arg Tyr Asn Phe225(2) SEQ ID NO:705 information

Sequence properties:

(A) length: 65 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...65

(xi) sequence representation: 705 SEQ ID NO: Ser Ala Val Val Glu Ser Val Val Ile Leu Lys Ile Asp Ile Asn Gln 151015 Gly Arg Ser Cys Ser Leu Tyr Pro Thr Pro Lys Ser Val Ser Leu Val

20 25 30Arg Asn Gln Ser Val Ala Tyr Glu Ile Leu Cys Glu Asn Gln Pro Leu

35 40 45Trp Ile Glu Val Ser Thr Asn Leu Gly Gln Thr Leu Pro Phe Ser Leu

505560 Ile65(2) SEQ ID NO:706 information

Sequence properties:

(A) length: 365 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...365

(xi) sequence representation: 706: Arg Phe Lys His Phe Arg Gly Gly Gly Phe Pro His His Asn Leu Asn 151015 Ala Cys Gly Ala Lys Pro Thr Gly Gln Val Val Phe Tyr Pro Thr Asn SEQ ID NO

20 25 30Ser Leu Leu Gly Ser Thr Ser Ser Asn Ser Asn Asn Gln Gln Gln Tyr

35 40 45Asn Asn Thr Leu Leu Met Asn Thr Leu Gln Gly Glu Leu Ser Thr Asn

50 55 60Asn Gln Asn Asn Pro Asn Gly Cys Ala Asn Gln Ile Gln Cys Leu Glu65 70 75 80Gln Phe Ile Gln Asn Leu Thr Pro Leu Ala Ala Thr Pro Thr Ser Thr

85 90 95Asn Gln Ala Asn Gln Gln Val Gln Ala Ile Ala Gln Lys Leu Gln Ser

100 105 110Val Ala Ile Asn Ala Leu Asp Asn Asn Ala Ile Asn Asn Thr Thr Tyr

115 120 125Asn Leu Asn Asn Leu His Asn Ala Leu Asn Phe Gln Ala Tyr Gln Ser

130 135 140Thr Ile Glu Gln Tyr Asn Asn Ala Leu Lys Gln Ile Ser Trp Ile Ser145 150 155 160Phe Ser Glu Pro Lys Asn Leu Leu Lys Asn Thr Ser Asn Asn Tyr Gln

165 170 175Ile Gly Thr Val Thr Asn Asp Gln Gly Gln Asn Ile Ser Ala Tyr Asp

180 l85 190Cys Thr Ser Ala Thr Gly Ser Leu Ser Ser Asp Ala Ser Ser Gly Ile

195 200 205Ser Cys Ser Ala Thr Ser Ser Thr Ser Asn Thr Asn Ser Phe Asp Asn

210 215 220Ser Leu Val Ala ThrSer Lys Val Gln Thr Ile Asn Gly Lys Glu Gln225 230 235 240Ile Gly Val Asn Ser Phe Asn Leu Val Ser Gln Val Trp Ser Val Tyr

245 250 255Asn Ser Leu Lys Thr Ser Glu Glu Asn Leu Gln Lys Asn Ala Lys lle

260 265 270Leu Cys Asn Asn Gly Ser Gln Ser Gly Thr Ser Pro Cys Asn Ser Ser

275 280 285Ser Gly Gly Leu Ser Ile Ser Gly Asn Ala Gln Leu Gln Asn Ile Leu

290 295 300Ser Pro Thr Asn Gly Thr Thr Thr Asn Thr Gln Ala Lys Ser Asn Ala305 310 315 320Ser Lys Leu Lys Ala Met Val Met Val Asn Asn Glu Glu Glu Ala Lys

325 330 335Thr Thr Asn Phe Asn Gln Ser Ser Gly Pro Thr Thr Gln Ser Ser Asn

340 345 350Ser Thr Val Met Gly Ala Leu Asn Thr Val Leu Gln Asn

355360365 (2) SEQ ID NO 707 information

Sequence properties:

(A) length: 135 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...135

(xi) sequence representation: 707 SEQ ID NO: Asn Pro Phe Phe Thr Ile Thr Ala Lys Leu Leu Ser Asn Thr Gln Ser 151015 Ala Phe Asp Gln Gly Ile Ala Leu Ser Ser Asn Ile Ile Ser Ala Val

20 25 30Asn Ser Leu Asn Pro Ser Asn Asn Ser Gln Glu Val Lys Ala Gln Leu

35 40 45Gln Asn Thr Ala Gln Ser Met Thr Glu Leu Leu Gln Gln Ile Glu His

50 55 60Ser Ile Thr Lys Thr Thr Ser Thr Thr Tyr Ala Gln Ser Leu Leu Ser65 70 75 80Asn Leu Thr Asp Ala Val Asn Ala Ser Ser Asn Asn Thr Thr Tyr Val

85 90 95Ser Ala Leu Val Asn Ala Leu Asn Thr Leu Gly Val Gly Val Phe Pro

100 105 110Thr Thr Thr Ser Thr His Val Val Leu Asn Pro Pro Asp Lys Ser Tyr

115 120 125Ser Ile Gln Leu Ile Pro Phe

130135 (2) SEQ ID NO 708 information

Sequence properties:

(A) length: 91 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...91

(xi) sequence representation: 708: Gly Arg Gly Met Lys Leu Lys Lys Arg Lys Val Ala Ala Thr Leu Leu 151015 Lys Arg Leu Thr Leu Pro Leu Leu Phe Thr Thr Gly Ser Leu Gly Ala SEQ ID NO

20 25 30Val Thr Tyr Glu Val His Gly Asp Phe Ile Asn Phe Ser Lys Val Gly

35 40 45Phe Asn Arg Ser Pro Ile Asn Pro Val Lys Gly Ile Tyr Pro Thr Glu

50 55 60Thr Phe Val Asn Leu Thr Gly Lys Leu Glu Gly Ser Val His Leu Gly65 70 75 80Arg Gly Trp Thr Val Asn Val Gly Gly Val Leu

8590 (2) SEQ ID NO:709 information

Sequence properties:

(A) length: 721 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...721

(xi) sequence representation: SEQ ID NO:709: Met Glu Gln Pro Val Ile Lys Glu Gly Thr Leu Ala Leu Ile Asp Thr 151015 Phe Ala Tyr Leu Phe Arg Ser Tyr Tyr Met Ser Ala Lys Asn Lys Pro

20 25 30Leu Thr Asn Asp Lys Gly Phe Pro Thr Gly Leu Leu Thr Gly Leu Val

35 40 45Gly Met Val Lys Lys Phe Tyr Lys Asp Ar9 Lys Asn Met Pro Phe Ile

50 5560Val Phe Ala Leu Glu Ser Gln Thr Lys Thr Lys Arg Ala Glu Lys Leu65 70 75 80Gly Glu Tyr Lys Gln Asn Arg Lys Asp Ala Pro Lys Glu Met Leu Leu

85 90 95Gln Ile Pro Ile Ala Leu Glu Trp Leu Gln Lys Met Gly Phe Thr Cys

100 105 110Val Glu Val Gly Gly Phe Glu Ala Asp Asp Val Ile Ala Ser Leu Ala

115 120 125Thr Leu Ser Pro Tyr Lys Thr Arg Ile Tyr Ser Lys Asp Lys Asp Phe

130 135 140Asn Gln Leu Leu Ser Asp Lys Ile Ala Leu Phe Asp Gly Lys Thr Glu145 150 155 160Phe Leu Ala Lys Asp Cys Val Glu Lys Tyr Gly Ile Leu Pro Ser Gln

165 170 175Phe Thr Asp Tyr Gln Gly Ile Val Gly Asp Ser Ser Asp Asn Tyr Lys

180 185 190Gly Val Lys Gly Ile Gly Ser Lys Asn Ala Lys Glu Leu Leu Gln Arg

195 200 205Leu Gly Ser Leu Glu Lys Ile Tyr Glu Asn Leu Asp Leu Ala Lys Asn

210 215 220Leu Leu Ser Pro Lys Met Tyr Gln Ala Leu Ile Gln Asp Lys Gly Ser225 230 235 240Ala Phe Leu Ser Lys Glu Leu Ala Thr Leu Glu Arg Gly Cys Ile Lys

245 250 255Glu Phe Asp Phe Leu Ser Cys Ala Phe Pro Ser Glu Asn Pro Leu Leu

260 265 270Lys Ile Lys Asp Glu Leu Lys Glu Tyr Gly Phe Ile Ser Thr Leu Arg

275280 285Asp Leu Glu Asn Ser Pro Phe Ile Val Glu Asn Val Pro Ile Leu Asn

290 295 300Ser Thr Pro Ile Leu Asp Asn Thr Pro Ala Leu Asp Asn Ala Pro Lys305 310 315 320Lys Ser Arg Met Ile Val Leu Glu Ser Ala Glu Pro Leu Ser Met Phe

325 330 335Leu Glu Lys Leu Glu Asn Pro Asn Ala Arg Val Phe Met Arg Leu Val

340 345 350Leu Asp Lys Asp Lys Lys Ile Leu Ala Leu Ala Phe Leu Leu Gln Asp

355 360 365Gln Gly Tyr Phe Leu Pro Leu Glu Glu Ala Leu Phe Ser Pro Phe Ser

370 375 380Leu Glu Phe Leu Gln Asn Ala Phe Ser Gln Met Leu Gln His Ala Cys385 390 395 400Ile Ile Gly His Asp Leu Lys Pro Leu Leu Ser Phe Leu Lys Ala Lys

405 410 415Tyr Gln Val Pro Leu Glu Asn Ile Arg Ile Gln Asp Thr Gln Ile Leu

420 425 430Ala Phe Leu Lys Asn Pro Glu Lys Val Gly Phe Asp Glu Val Leu Lys

435 440 445Glu Tyr Leu Lys Glu Asp Leu Ile Pro His Glu Lys Ile Lys Asp Phe

450 455 460Lys Thr Lys Ser Lys Ala Glu Lys Ser Glu Leu Leu Ser Met Glu Leu465 470 475 480Asn Ala Leu Lys Arg Leu Cys Glu Tyr Phe Glu Lys Gly Gly Leu Glu

485 490 495Glu Asp Leu Leu Thr Leu Ala Arg Asp Ile Glu Thr Pro Phe Val Lys

500 505510Val Leu Met Gly Met Glu Phe Gln Gly Phe Lys Ile Asp Ala Ala Leu

515 520 525Glu Asn Ile Val Ile Ala Gly Val Thr Asn Lys Pro Asn Gly Ala Gly

530 535 540Ala Ile Thr Ser Thr Gly His Val Thr Asp Tyr Ala Val Phe Asn Asn545 550 555 560Ile Lys Ala Met Leu Pro Ile Leu Gln Gln Ala Leu Thr Leu Ser Gln

565 570 575Ser Asn His Thr Leu Ser Thr Gln Leu Gln Ala Arg Ala Met Gly Ser

580 585 590Gln Thr Asn Arg Glu Phe Ala Lys Asp Ile Tyr Ala Leu Ala Gln Asn

595 600 605Gln Lys Gln Ile Leu Ser Asn Ala Ser Ser Ile Phe Asn Leu Phe Asn

610 615 620Ser Ile Pro Lys Asp Gln Leu Lys Tyr Leu Glu Asn Ala Tyr Leu Lys625 630 635 640Val Pro His Leu Gly Lys Thr Pro Thr Asn Pro Tyr Arg Gln Asn Val

645 650 655Asn Leu Asn Lys Glu Ile Asn Ala Val Gln Asp Asn Val Ala Asn Tyr

660 665 670Gly Asn Arg Leu Asp Ser Ala Leu Ser Val Ala Lys Asp Val Tyr Asn

675 680 685Leu Lys Ser Asn Gln Thr Glu Ile Val Thr Thr Tyr Asn Asp Ala Lys

690695700 Asn Leu Gly Pro Gly Val Ser Lys Leu Pro Cys Arg Cys Leu Glu Lys 705710715720 Ile (2) SEQ ID NO 710 information

Sequence properties:

(A) length: 76 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...76

(xi) sequence representation: 710: Thr Ser Leu Ser Leu Phe Gly Glu Asp Leu Ala Lys Glu Lys Arg Ser 151015 Ile Ala Lys Ser Ile Asn Phe Gly Leu Val Tyr Gly Met Gly Ser Lys SEQ ID NO

20 25 30Lys Leu Ser Glu Thr Leu Ser Ile Pro Leu Ser Glu Ala Lys Ser Tyr

35 40 45Ile Glu Ala Tyr Phe Lys Arg Phe Pro Ser Ile Lys Asp Tyr Leu Asn

505560 Gly Men Arg Glu Glu Ile Leu Lys Thr Ser Lys Ala 657075 (2) SEQ ID NO:711 information

Sequence properties:

(A) length: 325 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...325

(xi) sequence representation: 711: Lys Glu Lys Asp Asn Pro Leu Gln Asn Phe Val Phe Asn Lys Lys Trp 151015 Leu Ile Tyr Ser Ser Leu Leu Pro Leu Phe Phe Leu Asn Pro Leu Met SEQ ID NO

20 25 30Ala Glu Asp Asp Gly Phe Phe Met Gly Val Ser Tyr Gln Thr Ser Leu

35 40 45Ala Val Gln Arg Val Asp Asn Ser Gly Leu Asn Ala Ser Gln Asp Ala

50 55 60Ser Thr Tyr Ile Arg Gln Asn Ala Ile Ala Leu Glu Ser Ala Ala Val65 70 75 80Pro Leu Ala Tyr Tyr Leu Glu Ala Met Gly Gln Gln Thr Arg Val Leu

85 90 95Meu Gln Met Leu Cys Pro Asp Pro Ser Lys Arg Cys Leu Leu Tyr Ala

100 105 110Gly Gly Tyr Gln Asn Gly Gln Asn Asn Asn Gly Asp Thr Gly Asn Asn

115 120 125Pro Pro Arg Gly Asn Val Asn Ala Thr Phe Asp Met Gln Ser Leu Val

130 135 140Asn Asn Leu Asn Lys Leu Thr Gln Leu Ile Gly Glu Thr Leu Ile Arg145 150 155 160Asn Pro Glu Asn Leu Pro Asn Ser Lys Val Phe Asn Val Lys Phe Gly

165 170 175Asn Gln Ser Thr Val Ile Ala Leu Pro Glu Gly Leu Ala Asn Thr Met

180 185 190Asp Ala Leu Asn Asn Asp Ile Thr Asn Ala Leu Thr Thr Leu Trp Tyr

195 200 205Asn Gln Thr Leu Thr Asn Lys Ser Phe Ser Thr Pro Ser Asn Thr Ser210 215 220Val Asn Phe Ser Pro Gln Val Leu Gln His Leu Leu Gln Asp Gly Leu225 230 235 240Ala Thr Ala Asn Asn Asn Gln Thr Ile Cys Ser Thr Gln Asn Gln Cys

245 250 255Thr Ala Thr Asn Glu Ala Lys Ser Ile Ala Gln Asn Ala Gln Asn Ile

260 265 270Phe Gln Ala Leu Met Gln Ala Gly Ile Leu Gly Gly Leu Ala Asn Glu

275 280 285Lys Gln Phe Gly Phe Thr Tyr Asn Lys Ala Pro Asn Gly Gly Asp Ser

290 295 300Gln Gln Gly Tyr Ser Lys Leu Cys Gly Pro Gly Ile Thr Pro Lys Arg305 310 315 320Gln His His Ala Ser

325(2) SEQ ID NO 712 information

Sequence properties:

(A) length: 280 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...280

(xi) sequence representation: 712: Tyr Asn Gln Met Gln Asp Val Ile Asn Tyr Gly Glu Ser Leu Leu Ser 151015 Asn Thr Val Ala Tyr Gly Asp Phe Ile Thr Asn Trp Val Ala Pro Tyr SEQ ID NO

20 25 30Leu Asp Leu Asn Asn Lys Gly Leu Asn Phe Leu Pro Asn Tyr Gly Gly

35 40 45Gln Leu Asn Gly Ala Asn Asn Gln Thr Pro Gln Leu Thr Pro Gln Gln

50 5560Ala Gln Gln Glu Gln Lys Val Ile Met Asn Gln Leu Glu Gln Ala Thr65 70 75 80Asn Ala Pro Thr Pro Ala Gln Ile Asn Arg Ile Leu Ala Asn Pro Tyr

85 90 95Ser Pro Thr Ala Lys Thr Leu Met Ala Tyr Gly Leu Tyr Arg Ser Lys

100 105 110Ala Val Ile Gly Gly Val Ile Asp Glu Met Gln Thr Lys Val Asn Gln

115 120 125Val Tyr Gln Met Gly Phe Ala Arg Asn Phe Leu Glu His Thr Leu Tyr

130 135 140Ile Leu Ile Thr Leu Asn Gly Phe Gly Val Lys Met Gly Tyr Lys Gln145 150 155 160Phe Phe Gly Lys Lys Arg Met Phe Gly Leu Arg Tyr Tyr Gly Phe Tyr

165 170 175Asp Phe Gly Tyr Ala Gln Phe Gly Thr Glu Ser Ser Leu Val Lys Ala

180 185 190Thr Leu Ser Ser Tyr G1y Ala Gly Thr Asp Phe Leu Tyr Asn Val Phe

195 200 205Thr Arg Lys Arg Gly Thr Glu Ala Ile Asp Ile Gly Phe Phe Ala Gly

210 215 220Ile Gln Leu Ala Gly Gln Thr Trp Lys Thr Asn Phe Leu Asp Gln Val225 230 235 240Asp Gly Asn His Leu Lys Pro Lys Asp Thr Ser Phe Gln Phe Leu Phe

245 250 255Asp Leu Gly Ile Met Asp Gln Ile Phe Pro Lys Ser Leu Ile Ser Lys

260 265 270Lys Asn Leu Val Phe Leu Lys Gly

275280 (2) SEQ ID NO 713 message

Sequence properties:

(A) length: 135 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...135

(xi) sequence representation: SEQ ID NO. 713: Gln Pro His Lys Gln Arg Asn Ile Ala His Leu Gln His Ala Gln Ala 151015 Val Ile Thr Ser Val Leu Ala Phe Trp Ser Leu Tyr Ala Gly Asn Ala

20 25 30Leu Ser Phe His Val Thr Gly Leu Asn Asp Gly Ser Asn Ser Pro Leu

35 40 45Gly Arg Ile His Arg Asp Gly Asn Cys Thr Gly Leu Gln Gln Cys Phe

50 55 60Met Ser Lys Glu Thr Tyr Asp Lys Met Lys Thr Leu Ala Glu Asn Leu65 70 75 80Gln Lys Ala Gln Gly Asn Leu Cys Ala Leu Ser Glu Cys Ser Ser Asn

85 90 95Gln Asp Ser Gly Phe Pro Val Leu Asp Ser Ala Gly Lys Gln Val Thr

100 105 110Ile Thr Ile Thr Thr Gln Thr Asn Gly Ala Asn Lys Ser Glu Thr Thr

115 120 125Thr Thr Thr Thr Thr Thr Asn

130135 (2) information SEQ ID NO:714

Sequence properties:

(A) length: 124 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...124

(xi) sequence representation: 714: Gly Leu Ser Arg Gln Gly Asn Glu Arg Leu Asp Ala Thr Leu Asn Leu 151015 Lys Thr Gly Val Gln Ser Phe Phe Lys Lys Tyr Ile Gly Ile Arg Gly SEQ ID NO

20 25 30Val Phe Ala Trp Asp Leu Gly Ser Gly Lys Val Asn Tyr Gln Ser Tyr

35 40 45Lys Asp Pro Thr Asn Ser Phe Phe Thr Met Leu Ala Val Gly Leu Asp

50 55 60Val Ile Met Glu Phe Pro Leu Gly Ser Tyr Lys His Tyr Leu Gly Ala65 70 75 80Phe Gly Gly Ala Arg Gly Ala Leu Val Val Tyr Thr Asp Lys Gln Asn

85 90 95Phe Lys Phe Phe Lys His Ser Val Val Ser Gly Gly Leu Ala Ile Ser

100 105 110Gly Gly Trp Leu Ile Leu Leu Arg Thr Pro His Phe

115120 (2) SEQ ID NO 715 message

Sequence properties:

(A) length: 103 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 103

(xi) sequence representation: 715: Pro Val Gly Leu Tyr Pro Leu Glu Ser Pro Leu Ile Tyr Glu Glu Asn 151015 Bis Leu Leu Pro Met Gly Phe Ile His Leu Ala Phe Arg Gly Gly Gly SEQ ID NO

20 25 30Ser Leu Ser Asp Lys Asn Gln Leu Gly Leu Ala Lys Leu Phe Ala Gln

35 40 45Val Leu Asn Glu Gly Thr Lys Glu Leu Gly Ala Val Gly Phe Ala Gln

50 55 60Leu Leu Glu Gln Lys Ala Ile Ser Leu Asn Val Asp Thr Ser Ala Glu65 70 75 80Asp Leu Gln Ile Thr Leu Glu Phe Leu Lys Glu Tyr Glu Asp Glu Ala

85 90 95Ile Met Arg Leu Lys Glu Leu

100(2) SEQ ID NO 716 information

Sequence properties:

(A) length: 85 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...85

(xi) sequence representation: 716: Tyr Ser Val Tyr Ile Arg Ser Asn Phe Ser Lys Val Ala His Phe Ala 151015 Ser Gly Tyr Leu Gln Thr Lys Leu Ser Thr Gln Ala Lys Ser Val Ala SEQ ID NO

20 25 30Leu Ala Lys Lys Thr Thr Lys Glu Phe Ile Glu Lys Gly Met Thr Gln

35 40 45Gln Glu Leu Asp Asp Ala Lys Lys Phe Leu Leu Gly Ser Glu Pro Leu

50 55 60Arg Asn Glu Thr Ile Ser Ser Arg Leu Asn Thr Thr Tyr Asn Tyr Phe65 70 75 80Ile Trp Val Cys Leu

85(2) SEQ ID NO 717 information

Sequence properties:

(A) length: 343 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...343

(xi) sequence representation: SEQ ID NO. 717: Arg Arg Ala Trp Ile Leu Leu Gly Leu Lys Asn Leu Lys Gly Val Trp 151015 Val Leu Lys Gly Leu Lys Lys Ala Phe Lys Glu Arg Phe Cys Ser Gln

20 25 30Val Tyr Ile Ser Phe Asn Val Asp His Asn Leu Leu Ser Ala Gln Val

35 40 45Leu Arg Val Lys Asn His Arg Ile Lys Glu Lys Phe Phe Lys Thr Phe

50 55 60Glu Thr Lys Val Glu Thr Lys Asn Gly Glu Val Pro Ile Gln Ala Leu65 70 75 80Lys Ile Ala Arg Thr Tyr Ser Gln Lys Tyr Pro Tyr Thr Tyr Phe Ser

85 90 95Ala Met Ser Lys Ala Lys Glu Val Leu Cys Glu Lys Gln Ala Phe Glu

100 105 110Gln Ile Lys Gln Glu Asn Gln Asp Tyr Gln Ala Cys Glu Val Asn Gln

115 120 125Lys Tyr Cys Val Tyr Val Glu Ser Lys Asp Phe Leu Lys Asp Phe Lys

130 135 140Arg Phe Lys Ile Gln Asp Val Asp Phe Leu Phe Ser Pro Phe Ser Leu145 150 155 160Ile Tyr Asp Phe Val Arg Asp Asn Leu Glu Asn Lys Pro Leu Leu Tyr

165 170 175Leu Leu Leu Glu Arg Ser Arg Phe Tyr Phe Leu Ile Ala Asp Lys Lys

180 185 190Glu Ile Phe Leu Ala Lys Ser Val Phe Leu Glu Glu Gln Pro Glu Glu

195 200 205Phe Ile Glu Ser Lys Glu Glu Asp Ser Met Gly Met Asp Asn Glu Ala

210 215 220Val Asp Leu Phe Leu Ser Glu Ile Gln Glu Asp Ile Asp Ser Leu Glu225 230 235 240Glu Ala Ile Gly Leu Asp Ser Ser Lys Asp Asn Ser Glu Lys Ile Thr

245 250 255Glu Asp Ala Tyr Ser Leu Ile Glu Gly Met Thr Asn Ile Pro Leu Ile

260 265 270Ala Asp Val Leu Gln Glu Gly Leu Arg Gly Val Tyr His Ser Arg Glu

275 280 285Ile Asp Phe Val Glu Lys Val Val Val Leu Asp Ser Cys Gln Ile His

290 295 300His Lys Ala Leu Met His Leu Gln Glu Thr Leu Met Ile Glu Val Asp305 310 315 320Arg Leu Asp Phe Ser Leu Val Glu Arg Leu Asn Val Leu Ala Arg Met

325 330 335Glu Asn Glu Lys His Ala Phe

340(2) SEQ ID NO 718 information

Sequence properties:

(A) length: 420 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...420

(xi) sequence representation: SEQ ID NO 718: Met Ile Phe Gly Asp Phe Lys Tyr Gln Lys Ser Val Lys Lys Leu Thr 151015 Ala Thr Asn Leu Asn Glu Leu Lys Asn Ala Leu Asp Phe Ile Ser Gln

20 25 30Asn Arg Gly Lys Gly Tyr Phe Val Gly Tyr Leu Leu Tyr Glu Ala Arg

35 40 45Leu Ala Phe Leu Asp Glu Asn Phe Gln Ser Gln Thr Pro Phe Leu Tyr

50 5560Phe Glu Gln Phe Leu Glu Arg Lys Lys Tyr Leu Val Glu His Leu Lys65 70 75 80Glu His Ala Phe Tyr Pro Lys Ile His Ser Ser Leu Asp Gln Lys Thr

85 90 95Tyr Phe Lys Gln Phe Lys Ala Val Lys Glu His Leu Lys Asn Gly Asp

100 105 110Thr Tyr Gln Val Asn Leu Thr Met Asp Leu Leu Leu Asn Thr Lys Ala

115 120 125Lys Pro Lys Arg Val Phe Lys Glu Val Ile His Asn Gln Asn Thr Pro

130 135 140Phe Lys Ala Phe Ile Glu Asn Glu Phe Gly Ser Val Leu Ser Phe Ser145 150 155 160Pro Glu Leu Phe Phe Glu Leu Glu Phe Leu Asp Thr Ala Ile Lys Ile

165 170 175Ile Thr Lys Pro Met Lys Gly Thr Ile Ala Arg Ser Asn Asn Pro Leu

180 185 190Ile Asp Glu Lys Asn Arg Leu Phe Leu Gln Asn Asp Asp Lys Asn Arg

195 200 205Ser Glu Asn Val Met Ile Val Asp Leu Leu Arg Asn Asp Leu Ser Arg

210 215 220Leu Ala Leu Lys Asn Ser Val Lys Val Asn Gln Leu Phe Glu Ile Ile225 230 235 240Ser Leu Pro Ser Val Tyr Gln Met Ile Ser Glu Ile Glu Ala Gln Leu

245 250 255Pro Leu Lys Thr Ser Leu Phe Glu Ile Phe Lys Ala Leu Phe Pro Cys

260 265 270Gly Ser Val Thr Gly Cys Pro Lys Ile Lys Thr Met Gln Ile Ile Glu

275 280 285Ser Leu Glu Lys Arg Pro Arg Gly Val Tyr Cys Gly Ala Ile Gly Met

290 295 300Val Gly Gly Lys Lys Ala Leu Phe Ser Val Pro Ile Arg Thr Leu Glu305 310 315 320Lys Arg Ala His Glu Asp Phe Leu His Leu Gly Val Gly Ser Gly Val

325 330 335Thr Tyr Lys Ser Lys Ala Ser Lys Glu Tyr Glu Glu Ser Phe Leu Lys

340 345 350Ser Phe Phe Val Met Pro Lys Ile Glu Phe Glu Ile Val Glu Thr Met

355 360 365Arg Val Ile Lys Arg Asp Gln Lys Leu Glu Ile Asn Asn Lys Asn Ala

370 375 380His Lys Glu Arg Leu Met His Ser Ala Gln Tyr Phe Asn Phe Asn Thr385 390 395 400Asp Glu Asn Leu Leu Asp Phe Glu Leu Glu Gly Glu Gly Val Leu Arg

405 410 415Val Leu Ile Gln

420(2) SEQ ID NO 719 information

Sequence properties:

(A) length: 285 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...285

(xi) sequence representation: 719: Lys Gln Ile Arg Lys Glu Arg Leu Asn Lys Leu Leu Lys Lys Gly Phe 151015 Leu Ala Phe Phe Leu Ser Val Tyr Leu Arg Ala Asp Asp Leu Val Thr SEQ ID NO

20 25 30Tyr Thr Ile Ala Lys Glu Glu Asp Leu Gly Tyr Gln Arg Phe Leu Ala

35 40 45Lys Lys Cys Leu Arg Gly Lys Thr His Pro Pro Cys Phe Thr Ala Ser

50 55 60Lys Lys Pro Lys Arg Lys Pro Phe Asn Ile Asp Lys Ser Ser His Tyr65 70 75 80Tyr Gly Thr Ser Val Val Gln Met Ser Trp Leu Gln Ser Arg Glu Lys

85 90 95Phe Glu Asn His Ser Lys Tyr Arg Asn Ile Pro Phe Ala Glu Val Ser

100 105 110Leu Ile Tyr Gly Tyr Lys Gln Phe Phe Pro Lys Lys Glu His Tyr Gly

115 120 125Phe Arg Phe Tyr Val Ser Leu Asp Tyr Ala Tyr Gly Phe Phe Leu Lys130 135 140Asn Lys Gly Ala Leu Gly Asp Ser Leu Arg Ala Ser Ser Gln Ile Pro145 150 155 160Lys Ser Tyr Arg Glu Lys Leu Gln Arg Lys Glu Thr Phe Ile Asn Ala

165 170 175Ile Phe Tyr Gly Val Gly Ala Asp Phe Leu Tyr Lys Arg Ala Phe Gly

180 185 190Thr Leu Ile Leu Gly Val Asn Phe Val Gly Glu Thr Trp Phe Tyr Glu

195 200 205Thr Lys Ile Phe Lys Gln Trp Ala Lys Asp Ser Leu Asn Thr Tyr Arg

210 215 220Pro Asn Met Phe Gln Val Met Leu Asn Val Gly Tyr Arg Tyr Arg Phe225 230 235240Ser Arg Tyr Lys Asn Trp Ala Ile Glu Phe Gly Ala Arg Ile Pro Phe

245 250 255Leu Ile Asn Asp Tyr Phe Lys Thr Pro Leu Tyr Thr Leu His Phe Lys

260 265 270Arg Asn Ile Ser Val Tyr Leu Thr Ser Thr Tyr Asp Phe

275280285 (2) SEQ ID NO 720 information

Sequence properties:

(A) length: 231 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...231

(xi) sequence representation: 720: Asn Thr Leu Phe Tyr Phe Phe Leu Leu Gln Ala Val Ile Val Leu Asp 151015 Ser Phe Glu Ile Leu Lys Ala Leu Lys Ser Leu Asp Leu Leu Lys Asn SEQ ID NO

20 25 30Ala Pro Ala Trp Trp Trp Pro Asn Ala Leu Lys Phe Glu Ala Leu Leu

35 40 45Gly Ala Val Leu Thr Gln Asn Thr Lys Phe Glu Ala Val Leu Lys Ser

50 55 60Leu Glu Asn Leu Lys Asn Ala Phe Ile Leu Glu Asn Asp Asp Glu Ile65 70 75 80Asn Leu Lys Lys Ile Ala Tyr Ile Glu Phe Ser Lys Leu Ala Glu Cys

85 90 95Val Arg ProSer Gly Phe Tyr Asn Gln Lys Ala Lys Arg Leu Ile Asp

100 105 110Leu Ser Lys Asn Ile Leu Lys Asp Phe Gln Ser Phe Glu Asn Phe Lys

115 120 125Gln Glu Val Thr Lys Glu Trp Leu Leu Asp Gln Lys Gly Ile Gly Lys

130 135 140Glu Ser Ala Asp Ala Ile Leu Cys Tyr Val Cys Ala LyS Glu Val Met145 150 155 160Val Val Asp Lys Tyr Ser Tyr Leu Phe Leu Lys Lys Leu Gly Ile Glu

165 170 175Ile Glu Asp Tyr Asp Glu Leu Gln His Phe Phe Glu Lys Gly Val Gln

180 185 190Glu Asn Leu Asn Ser Ala Leu Ala Leu Tyr Glu Asn Thr Ile Ser Leu

195 200 205Ala Gln Leu Tyr Ala Arg Phe His Gly Lys Ile Val Glu Phe Ser Lys

210215220 Gln Lys Leu Glu Leu Lys Leu 225230 (2) SEQ ID NO:721 information

Sequence properties:

(A) length: 231 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...231

(xi) sequence representation: 721: Ile Ser Phe Asn Ala Asp Tyr Phe Arg Ile Trp Ala Arg Asp Phe Ala 151015 Thr Gly Gln Tyr Ser Val Tyr Thr Ser Gly Pro Met Lys Gly Asn Val SEQ ID NO

20 25 30Arg Pro Ile Asn Gly Tyr Ser Gln Gly Val Glu Leu Glu Leu Tyr Tyr

35 40 45Arg Pro Ile Arg Gly Leu Gln Phe His Ala Ala Phe Asn Tyr Ile Asp

50 55 60Thr Arg Val Thr Ser His Gly Pro Leu Thr Asp Leu Asn Gly Asp Val65 70 75 80Leu Lys Gly Thr Ser Tyr Asn Lys His Phe Pro Phe Val Ser Pro Phe

85 90 95Gln Phe Ile Phe Asp Ala Arg Tyr Asn Trp Arg Lys Thr Thr Ile Gly

100 105 110Ile Ser Ser Tyr Phe Tyr Ser Arg Ala Tyr Ser Gly Ile Ser Asn Ser

115 120 125Ala Ala Gly Gly Tyr Tyr Gly Met Gln Tyr Tyr Ser Gly Gly Asn Asn

130 135 140Tyr Glu Ser Val Leu Asn Ser Gly Tyr Gln Cys Glu Ala Trp Cys Met145 150 155 160Thr Gln His Glu Gly Leu Leu Pro Trp Tyr Trp Val Trp Asn Ile Gln

165 170 175Val Ser Gln Ile Phe Trp Glu Asn Gly Arg His Arg Val Thr Gly Ser

180 185 190Leu Gln Ile Asn Asn Ile Phe Asn Met Lys Tyr Tyr Phe Thr Gly Ile

195 200 205Gly Ser Ser Pro Ala Gly Leu Gln Pro Ala Pro Gly Arg Ser Val Thr

210215220 Ala Tyr Leu Asn Tyr Thr Phe 225230 (2) SEQ ID NO:722 information

Sequence properties:

(A) length: 268 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 268

(xi) sequence representation: 722 SEQ ID NO: Ser Gly Val Val Lys Met Lys Asp Lys Lys Ile Asp Glu Glu Thr Asn 151015 Ala Val Leu Glu Gly Glu Lys Tyr Thr Val Cys Val Ser Cys Gln Ile

20 25 30Gly Cys Gln Val Gly Cys Ser Phe Cys Phe Thr Gln Lys Gly Gly Phe

35 40 45Val Arg Asp Leu Lys Ala Ser Glu Ile Ile Gln Gln Ala Leu Leu Ile

50 55 60Lys Glu Ala Asn Asn Leu Pro Ile Glu Lys Ala Leu Asn Ile Val Phe65 70 75 80Met Gly Met Gly Glu Pro Leu Asn Asn Leu Asp Glu Val Cys Lys Ala

85 90 95Val Glu Ile Phe Asn Thr Gly Met Gln Ile Ser Pro Lys Arg Val Thr

100 105 110Ile Ser Thr Ser Gly Val Ala Asp Lys Ile Pro Ile Leu Ala Gly Lys

115 120 125Asn Leu Gly Val Gln Leu Ala Ile Ser Leu His Ala Val Asp Asp Lys

130 135 140Thr Arg Ser Ser Leu Met Pro Leu Asn Lys Lys Tyr Asn Ile Glu Cys145 150155 160Val Leu Asn Glu Val Arg Lys Trp Pro Leu Glu Gln Arg Lys Arg Val

l65 170 175Met Phe Glu Tyr Leu Leu Ile Lys Asp Leu Asn Asp Ser Leu Asp Cys

180 185 190Ala Lys Lys Leu Leu Lys Leu Leu Asn Gly Ile Lys Ser Lys Val Asn

195 200 205Leu Ile Leu Phe Asn Pro His Glu Gly Ser Lys Phe Glu Arg Pro Ser

210 215 220Leu Glu Ser Ala Arg Met Phe Ala Asn Phe Leu Asn Ala Lys Gly Leu225 230 235 240Leu Cys Thr Ile Arg Glu Sar Lys Ala Leu Asp Ile Glu Ala Ala Cys

245 250 255Gly Gln Leu Arg Glu Lys Lys Leu Gln Gln Lys Ile

260265 (2) SEQ ID NO 723 information

Sequence properties:

(A) length: 236 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...236

(xi) sequence representation: 723: Arg Leu Ser Glu Pro Ile Asp Arg Phe Thr Arg Ile Arg Trp Leu Phe 151015 Lys Asn Asp Phe Glu Lys Ile Arg Gln Gln Arg Val Leu Ile Cys Gly SEQ ID NO

20 2530Val Gly Gly Val Gly Gly Phe Ala Leu Asp Ser Leu Tyr Arg Val Gly

35 40 45Ile Gly Gln Ile Thr Ile Ile Asp Lys Asp Met Phe Asp Val Thr Asn

50 55 60Gln Asn Arg Gln Ile Gly Ser Glu Arg Ile Gly Glu Ser Lys Val Leu65 70 75 80Val Leu Gln Asp Leu Tyr Lys Gly Ile Gln Ala Leu Asn Cys Arg Ile

85 90 95Asp Glu Ala Phe Leu Ash Ser Phe Asn Phe Arg Asp Tyr Asp Tyr Ile

100 105 110Leu Asp Cys Met Asp Asp Leu Pro Ile Lys Thr Ser Leu Ala Ile Lys

115 120 125Cys Gln Asn Phe Ala Tyr Gly Lys Phe Ile Ser Ser Met Gly Ser Ala

130 135 140Lys Arg Leu Asn Pro Lys His Ile Gln Val Gly Ser Val Trp Glu Ser145 150 155 160Tyr Gly Asp Lys Phe Gly Arg Lys Phe Arg Asp Phe Leu Lys Lys Arg

165 170 175Arg Phe Lys Gly Asp Phe Lys Val Val Phe Ser Pro Glu Val Pro His

180 185 190Cys Ile Glu Leu Gly Ser Phe Asn Ala Val Thr Ala Ser Phe Gly Leu

195 200 205Gln Ile Ala Ser Glu Val Val Gln Asp Ile Ile Lys Asn Glu Arg Gln

210215220 Trp Asn Glu Arg Leu Arg Arg Arg Ile Gly Arg Phe 225230235 (2) SEQ ID NO:724 information

Sequence properties:

(A) length: 333 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...333

(xi) sequence representation: 724 SEQ ID NO: Ala Lys Ala Arg Val Gln Phe Asn Arg Ala Asn Glu Arg Gln Arg Arg 151015 Ala Lys Glu Phe Tyr Tyr Glu Glu Val Gln Lys Ala Ile Lys Glu Ile

20 25 30Asp Ser Ser Lys Lys His Asn Ile Asn Met Glu Arg Ser Arg Ala Glu

35 40 45Val Ser Glu Ile Leu Asn Asn Thr Tyr Ser Asn Leu Asp Lys Tyr Glu

50 55 60Ala Tyr Gln Gly Leu Leu Asn Pro Ala Val Ser Tyr Leu Ser Gly Leu65 70 75 80Phe Tyr Ala Leu Asn Gly Asp Lys Asn Lys Gly Leu Gly Tyr Leu Asn

85 90 95Glu Ala Tyr Gly Ile Ser Gln Ser Pro Phe Val Ala Gln Asp Leu Val

100 105 110Phe Phe Lys Asn Pro Asn Arg Ser His Phe Thr Trp Ile Ile Ile Glu

115 120 125Asp Gly Lys Glu Pro Gln Lys Ser Glu Phe Lys Ile Asp Val Pro Ile

130 135 140Phe Met Ile Asp Ser Val Tyr Asn Val Ser Val Ala Leu Pro Lys Leu145 150 155 160Glu Lys Gly Glu Ala Phe Tyr Gln Asn Phe Thr Leu Lys Asp Gly Glu

165 170 175Lys Val Thr Pro Phe Asp Thr Leu Ala Ser Ile Asp Ala Val Val Ala

180 185 190Ser Glu Phe Arg Lys Gln Leu Pro Tyr Ile Ile Thr Arg Ala Ile Leu

195 200 205Ser Ala Thr Phe Lys Val Gly Met Gln Ala Val Ala Asn Tyr Tyr Leu

210 215 220Gly Phe Val Gly Gly Leu Val Thr Ser Leu Tyr Ser Gly Val Ser Thr225 230 235 240Phe Ala Asp Thr Arg Asn Thr Ser Ile Phe Ala His Lys Ile Tyr Leu

245 250 255Met Arg Ile Lys Asn Lys Ala Phe Glu Ser Tyr Glu Val Arg Ala Asp

260 265 270Ser Ile Asp Ala Phe Ser Phe Ser Leu Lys Pro Cys Lys Arg Ser Leu

275 280 285Glu Ser Pro Lys Ile Ile Asp Ala Arg Glu Leu Leu Ser Gly Phe Val

290 295 300Thr Ala Pro Gln Val Phe Cys Ser Asn Arg His Asn Ile Leu Tyr Val305 310 315 320Arg Ser Phe Lys Asn Gly Phe Val Leu Ser His Leu Lys

325330 (2) SEQ ID NO 725 information

Sequence properties:

(A) length: 91 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...91

(xi) sequence representation: SEQ ID NO 725: Arg Asn Lys Asp Lys Arg Glu Tyr Phe Glu Asn Ala Thr Ala Gln Ile 151015 Gly Ala Lys Leu Leu Val Cys Asp Ile Arg Glu Gln Phe Phe Asn Asp

20 25 30Val Leu Phe Lys Pro Lys Tyr Gly Tyr Gly Lys Tyr Phe Asn Pro Cys

35 40 45Ile Asp Cys His Ala Asn Met Phe Arg Asn Ala Phe Tyr Lys Met Leu

50 55 60Glu Leu Asp Ala Asp Phe Val Leu Ser Gly Glu Val Leu Gly Asn Ala65 70 75 80Leu Asn Pro Lys Gly Lys Lys Aru Ser Ile Aru

8590 (2) SEQ ID NO 726 information

Sequence properties:

(A) length: 302 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...302

(xi) sequence representation: 726 SEQ ID NO: Gly Glu Val Met Ala Asp Ser Leu Ala Gly Ile Asp Gln Val Thr Ser 151015 Leu His Lys Asn Asn Glu Leu Gln Leu Leu Cys Phe Arg Leu Gly Lys

20 25 30Asn Lys Asp LeuTyr Ala Val Asn Val Phe Lys Ile Arg Glu Val Val

35 40 45Lys Tyr His Gly Asn Leu Thr Ile Ile Ser His Glu Asn Asn Ser Leu

50 55 60Val Glu Gly Leu Ile Ile Ile Arg Glu Leu Thr Ile Pro Leu Ile Asp65 70 75 80Met Lys Lys Trp Phe Tyr Tyr Asp Ser Gln Asn Lys Ser Lys Asp Leu

85 90 95Arg Pro Tyr Arg Ile Gln Lys Glu Lys Ser Glu Asp Asp Ile Val Met

100 105 110Ile Cys Glu Phe Ser Arg Trp Thr Ile Gly Val Arg Ile Tyr Glu Ala

115 120 125Asp Arg Ile Ser Ser Lys Lys Trp Thr Glu Met Glu Gln Ser Ala Gly

130 135 140Leu Arg Gly Ser Ala Gly Asn Asn Lys Leu Val Ser Arg Thr Arg Tyr145 150 155 160Phe Asp Gly Arg Leu Val Gln Val Val Asp Ile Glu Lys Met Leu Ile

165 170 175Asp Val Phe Pro Trp Ile Glu Asp Glu Lys His Asn Asp Val Glu Thr

180 185 190Leu Ser Lys Ile His Ser Asn Gln Cys Val Leu Leu Ala Asp Asp Ser

195 200 205Pro Ser Val Leu Lys Thr Met Gln Met Ile Leu Asp Lys Leu Gly Val

210 215 220Lys His Ile Asp Phe Ile Asn Gly Lys Thr Leu Leu Glu His Leu Phe225 230 235 240Asn Pro Thr Thr Asp Val Ser Asn Ile Asp Leu Ile Ile Thr Asp Leu

245 250 255Glu Met Pro Glu Ala Ser Gly Phe Glu Val IleAsn Gln Val Lys Asn

260 265 270Thr Pro Leu Thr Ser Thr Ile Pro Ile Val Val Asn Ser Ser Met Ser

275 280 285Gly Ser Ser Tyr Glu Lys Asn Gly Lys Asn Leu Asn Gly Gln

290295300 (2) information of SEQ ID NO:727

Sequence properties:

(A) length: 126 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...126

(xi) sequence representation: SEQ ID NO 727 Ala Val Ala Phe Cys Leu Pro Tyr Ser Ser Pro Lys Thr Ser Leu Ala 151015 Thr Glu Leu His Tyr Ser Ala Asn Glu Arg Ile Glu Ala Phe Ser Ser

20 25 30Asn Asp Glu Lys Thr Glu Ser Phe Glu Leu Asn Glu Gln Ser Phe Glu

35 40 45Ala Ile Lys Glu Asn Ala Ala Lys Tyr Ser Tyr Leu Lys Val Tyr Leu

50 55 60Lys Asn Val Ala Leu Lys Asp Ser Ala Pro Leu Val Phe Val Asp Met65 70 75 80Pro Gly Phe Asp Ser Pro Ile Ser Ser His Thr His Ala Ile Leu Glu

85 90 95Tyr Leu Glu Arg Gly Val His Phe Val Ile LeuThr Ser Val Glu Glu

100 105 110Gly Asn Leu Thr Lys Arg Met Val Arg Glu Leu Lys Thr Phe

115120125 (2) SEQ ID NO:728 information

Sequence properties:

(A) length: 325 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...325

(xi) sequence representation: SEQ ID NO 728: Arg His Pro Ile Glu Asn Ser Ile Cys Asp Leu Set Glu Leu Asn Asn 151015 Leu Lys Pro Leu Gly Ala Glu Met Phe Val Gly Leu Asp Gly Ile Asp

20 25 30Ala Met Ile Glu Glu Cys Val Ser Asn Leu Val Ile Asn Ala Ile Val

35 40 45Gly Val Pro Gly Leu Lys Ala Ser Phe Lys Ser Leu Gln Arg Asn Lys

50 55 60Lys Leu Ala Leu Ala Asn Lys Glu Ser Leu Val Ser Ala Gly His Leu65 70 75 80Leu Asp Ile Ser Gln Ile Tnr Pro Val Asp Ser Glu His Phe Gly Leu

85 90 95Trp Ala Leu Leu Gln Asn Lys Thr Leu Lys Pro Lys Ser Leu Ile Ile

100 105 110Ser Ala Ser Gly Gly Ala Phe Arg Asp ThrPro Leu Asp Leu Ile Ala

115 120 125Ile Gln Asn Ala Gln Asn Ala Leu Lys His Pro Asn Trp Ser Met Gly

130 135 140Asp Lys Ile Thr Ile Asp Ser Ala Ser Met Val Asn Lys Leu Phe Glu145 150 155 160Ile Leu Glu Thr Tyr Trp Leu Phe Gly Ala Ser Leu Lys Ile Asp Ala

165 170 175Leu Ile Glu Arg Asn Ser Ile Val His Ala Leu Val Glu Phe Glu Asp

180 185 190Asn Ser Val Ile Ala His Leu Ala Ser Ala Asp Met Gln Leu Pro Ile

195 200 205Ser Tyr Ala Ile Asn Pro Lys Leu Ala Ser Leu Ser Ala Ser Ile Lys

210 215 220Pro Leu Asp Leu Tyr Ala Leu Ser Ala Ile Lys Phe Glu Pro Ile Ser225 230 235 240Val Glu Arg Tyr Thr Leu Trp Arg Tyr Lys Asp Leu Leu Leu Glu Asn

245 250 255Pro Lys Leu Gly Val Val Leu Asn Ala Ser Asn Glu Val Ala Met Lys

260 265 270Lys Phe Leu Asn Gln Glu Ile Ala Phe Gly Gly Phe Ile Gln Ile Ile

275 280 285Ser Gln Ala Leu Glu Leu Tyr Ala Lys Lys Ser Phe Lys Leu Ser Ser

290 295 300Leu Asp Glu Val Leu Ala Leu Asp Lys Glu Val Arg Glu Arg Phe Gly305 310 315 320Ser Val Ala Arg Val

325(2) SEQ ID NO 729 information

Sequence properties:

(A) length: 132 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...132

(xi) sequence representation: SEQ ID NO 729: Glu Thr Leu Ala Arg Val Leu Lys Val Ser Cys Leu Ala Met Gly Leu 151015 Ala Gln Met Cys Cys Leu Thr Gln Leu Phe Ser Ile Val Arg Asn Leu

20 25 30His Leu Gly Phe Phe Leu Gly Val Ala Ile Gly Gly Thr Ser Trp Gly

35 40 45Pro Thr Asn Tyr Tyr Phe Lys Asp Leu Ala Glu Glu Tyr Arg Gly Ser

50 55 60Phe His Pro Ser Asn Phe Gln Val Leu Val Asn Gly Gly Ile Arg Leu65 70 75 80Gly Thr Lys His Gln Gly Phe Glu Ile Giy Leu Lys Ile Gln Thr Ile

85 90 95Arg Asn Asn Tyr Tyr Thr Ala Ser Ala Asp Asn Val Pro Glu Gly Thr

100 105 110Thr Tyr Arg Phe Thr Phe His Arg Pro Tyr Ala Phe Tyr Trp Arg Tyr

115 120 125Ile Val Ser Phe

130(2) SEQ ID NO 730 information

Sequence properties:

(A) length: 60 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...60

(xi) sequence representation: 730 SEQ ID NO Val Leu Lys Asn Glu Ile Ser Tyr Asn Lys Pro Iie Leu Asn Thr Asn 151015 Asp Tyr Leu Asn Lys Asp Asn Thr Met Lys Asp Ser Phe Leu Phe Thr

20 25 30Ser Glu Ser Val Thr Glu Gly His Pro Asp Lys Met Ala Asp Gln Ile

35 40 45Ser Asp Ala Val Leu Asp Tyr Met Ile Glu Arg Asp

505560 (2) information of SEQ ID NO:731

Sequence properties:

(A) length: 111 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...111

(xi) sequence representation: 731: Lys Thr Lys Val Ala Cys Lys Thr Leu Val Ser Asn Gly Leu Cys Met 151015 Ile Thr Gly Glu Leu Glu Thr Ser Val Tyr Ala Pro Met Leu Glu Ile SEQ ID NO

20 25 30Ala Arg His Met Val Arg Lys Ile Gly Tyr Thr Asn Ala Leu Tyr Cys

35 40 45Phe Asp Tyr Arg Ser Ala Ala Val Leu Asn Gly Ile Gly Glu Gln Ser

50 55 60Pro Asp Ile Asn Gln Gly Val Asp Arg Glu Asp Gly Glu Ile Gly Ala65 70 75 80Gly Asp Gln Gly Leu Met Phe Gly Tyr Ala Cys Lys GLu Thr Glu Thr

85 90 95Leu Met Pro Leu Pro Ile His Leu Ala His Gln Leu Ala Phe Ala

100105110 (2) SEQ ID NO:732 information

Sequence properties:

(A) length: 169 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...169

(xi) sequence representation: SEQ ID NO 732: Ser Leu Ser Thr Leu Ala Val Leu Leu Lys Ala Leu Asn Lys Arg Val 151015 Phe Gln Thr Ile Leu Asn Ala Ala Lys Asp Lys Lys Glu Gly Ala Ile

20 25 30Leu Ile Ala Ser Gly Cys Leu Ser Glu Arg Tyr Lys Asp Glu Ile Lys

35 40 45Glu Leu Ile Pro Glu Val Asp Ile Phe Thr Gly Val Gly Asp Tyr Asp

50 55 60Lys Ile Asp Ile Leu Ile Ala Lys Lys Gln Asn Gln Phe Ser Glu Gln65 70 75 80Val Phe Leu Ser Glu His Tyr Asn Ala Arg Ile Ile Thr Gly Ser Ser

85 90 95Val His Ala Tyr Val Lys Ile Ser Glu Gly Cys Asn Gln Lys Cys Ser

100 105 110Phe Cys Ala Ile Pro Ser Phe Lys Gly Lys Leu Gln Ser Arg Glu Leu

115 120 125Asp Ser Ile Leu Lys Glu Val Glu Asp Leu Ala Leu Lys Gly Tyr Lys

130 135 140Asp Met Thr Phe Ile Ala Gln Asp Sar Ser Ser Phe Leu Ser Asp Arg145 150 155 160Ala Lys Ser Arg Leu Asp Pro Ala His

165(2) SEQ ID NO 733 message

Sequence properties:

(A) length: 158 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...158

(xi) sequence representation: 733: Asn Leu Arg Thr Ile Met His Tyr Ser Tyr Glu Ala Phe Leu Lys Asp 151015 Ser Leu Glu Leu Ala Lys Gln Val Glu Arg Leu Cys Gly Ile Pro Glu SEQ ID NO

20 2530Ala Leu Val Cys Val Met Arg Gly Gly Met Thr Leu Val His Phe Leu

35 40 45Ser Leu His Trp Asn Leu Arg Glu Val Tyr Gly Ile Asn Ala Ile Ser

50 55 60Tyr Asp Thr Thr Lys Arg Gln Asn Ala Leu Lys Ile Glu Asn Thr Pro65 70 75 80Thr Ile Lys Asp Mis Leu Lys Thr Ile Leu Val Val Asp Glu Ile Val

85 90 95Asp Ser Gly Asn Ser Leu Glu Ala Val Leu Lys Val Leu Gln Asp Lys

100 105 110His Pro Asp Lys Lys Phe Tyr Ser Ala Ser Leu Phe Gln Lys Thr Ser

115 120 125Ala Lys Tyr Lys Ala Asp Ala Phe Leu Lys Asp Ala Pro Glu Trp Ire

130135140 Asp Phe Phe Trp Glu Val Asp Leu Lys Asn Leu Lys Ser His 145150155 (2) SEQ ID NO 734 information

Sequence properties:

(A) length: 227 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...227

(xi) sequence representation: SEQ ID NO 734: Ser Ser Ser Leu Glu Arg Leu Pro Ala Ser Leu Lys Asp Ala Arg Ile 151015 Leu Tyr Leu Tyr Pro Ser Ser Thr Thr Leu Glu Leu Ile Gly Ala Ile

20 25 30Glu Asp Ser Pro Ile Phe Gln Asn Tyr Phe Tyr Met Pro Ile Gln His

35 40 45Ile Ser Asp Ser Met Leu Lys Lys Met Arg Arg Asn Ser Ser Gln Ala

50 53 60His His Leu Lys Leu Leu Asn Ala Met Lys Gln Val Lys Glu Ser Phe65 70 75 80Ile Arg Ser Thr Ile Ile Val Gly His Pro Glu Glu Asn Glu Ser Glu

85 90 95Phe Glu Glu Leu Ser Ala Phe Leu Asp Glu Phe Arg Phe Asp Arg Leu

100 105 110Asn Ile Phe Ala Phe Ser Ala Glu Glu Asn Thr His Ala Tyr Ser Leu

115 120 125Glu Lys Val Pro Lys Lys Ile Ile Asn Ala Arg Ile Lys Ala Leu Asn

130 135 140Lys Ile Ala Leu Lys His Gln Asn His Ser Phe Lys Ala Leu Leu Asn145 150 155 160Lys Pro Ile Lys Ala Leu Val Glu His Lys Glu Gly Glu Tyr Phe Tyr

165 170 175Lys Ala Arg Asp Leu Arg Trp Ala Pro Glu Val Asp Gly Glu Ile Leu

180 185 190Ile Asn Asp Ser Glu Leu Thr Thr Pro Leu Lys Pro Gly His Tyr Thr

195 200 205Ile Val Pro Ser Ala Phe Lys Asp Asn Ile Leu Leu Ala Lys Val Leu

210215220 Ser Pro Phe225(2) SEQ ID NO:735 information

Sequence properties:

(A) length: 108 amino acid

(B) Type (2): aminoacids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...108

(xi) sequence representation: 735 SEQ ID NO: Ile Thr Asn Thr Thr Phe Gln Leu Gln Gly Val Leu Leu Glu Tyr Asp 151015 Phe Glu Arg Pro Ala Ile Ser Tyr Thr Pro Lys Lys Ser Val Phe Asn

20 25 30Glu Arg Leu Lys Asp Leu Arg Glu Asn Phe Ser Ala Ser Leu Tyr Ala

35 40 45Asp Leu Lys Asp Lys Ile His His Asn Ala Leu Ser Asn Asp Asp Leu

50 55 60Glu Arg Met Ile Ala Phe Arg Glu Gln Glu Phe Glu Lys Ser Leu Glu65 70 75 80Asp Trp Men Gly Ala Tyr Ser Tyr Asp Ala Thr Leu Arg Cys Phe Ser

85 90 95Ser Glu Arg Ile Tyr Leu Asp Arg Leu Gly Trp Glu

100105 (2) SEQ ID NO 736 message

Sequence properties:

(A) length: 364 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...364

(xi) sequence representation: SEQ ID NO 736: Lys Lys Val Val Met Asn Gly Phe Cys Ala Aru Leu Arg Ala Ile Thr 151015 Phe Asn Glu Arg Leu Lys Met Lys Ile Ala Val Leu Leu Ser Gly Gly

20 25 30Val Asp Ser Ser Tyr Ser Ala Tyr Ser Leu Lys Glu Gln Gly His Glu

35 40 45Leu Val Gly Ile Tyr Leu Lys Leu His Ala Ser Glu Lys Lys His Asp

50 55 60Leu Tyr Ile Lys Asn Ala Gln Lys Ala Cys Glu Phe Leu Gly Ile Pro65 70 75 80Leu Glu Val Leu Asp Phe Gln Lys Asp Phe Lys Ser Ala Val Tyr Asp

85 90 95Glu Phe Ile Asn Ala Tyr Glu Glu Gly Gln Thr Pro Asn Pro Cys Ala

100 105 110Leu Cys Asn Pro Leu Met Lys Phe Gly Leu Ala Leu Asp His Ala Leu

115 120 125Lys Leu Gly Cys Glu Lys Ile Ala Thr Gly His Tyr Ala Arg Val Lys

130 135 140Glu Ile Asp Lys Val Ser Tyr Ile Gln Glu Ala Leu Asp Lys Thr Lys145 150 155 160Asp Gln Ser Tyr Phe Leu Tyr Ala Leu Glu His Glu Val Ile Ala Lys

165 170 175Leu Val Phe Pro Leu Gly Asp Leu Leu Lys Lys Asp Ile Lys Pro Leu

180 185 190Ala Leu Asn Ala Met Pro Phe Leu Gly Thr Leu Glu Thr Tyr Lys Glu

195 200 205Ser Gln Glu Ile Cys Phe Val Glu Lys Ser Tyr Ile Asp Thr Leu Lys

210 215 220Lys His Val Glu Val Glu Lys Glu Gly Val Val Lys Asn Leu Gln Gly225 230 235 240Glu Val Ile Gly Thr His Lys Gly Tyr Met Gln Tyr Thr Ile Gly Lys

245 250 255Arg Lys Gly Phe Ser Val Lys Gly Ala Leu Glu Pro His Phe Val Val

260 265 270Gly Ile Asp Ala Lys Lys Asn Glu Leu Ile Val Gly Lys Lys Glu Asp

275 280 285Leu Ala Thr His Ser Leu Lys Ala Lys Asn Lys Ser Leu Thr Lys Asp

290 295 300Phe Lys Asp Gly Glu Tyr Phe Ile Lys Ala Arg Tyr Arg Ser Val Pro305 310 315 320Thr Lys Ala Phe Val Ser Leu Lys Asp Gly Met Ile Glu Val Glu Phe

325 330 335Lys Glu Pro Phe Tyr Gly Val Ala Lys Gly Gln Ala Leu Val Val Tyr

340 345 350Lys Asp Asp Ile Leu Leu Gly Gly Gly Val Ile Val

355360 (2) SEQ ID NO 737 information

Sequence properties:

(A) length: 133 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...133

(xi) sequence representation: 737: Leu Phe Lys Thr Asn Gly Ile Ser Val Gly Glu Tyr Thr His Phe Ser 151015 Glu Asp Ile Gly Ser Gln Ser Arg Ile Asn Thr Val Arg Leu Glu Thr SEQ ID NO

20 25 30Gly Thr Arg Ser Ile Phe Ser Gly Gly Val Lys Phe Lys Ser Gly Glu

35 40 45Lys Leu Val Ile Asn Asp Phe Tyr Tyr Ser Pro Trp Asn Tyr Phe Asp

50 55 60Ala Arg Asn Val Lys Asn Val Glu Ile Thr Arg Lys Phe Ala Ser Ser65 70 75 80Thr Pro Glu Asn Pro Trp Gly Thr Ser Lys Leu Met Phe Asn Asn Leu

85 90 95Thr Leu Gly Gln Asn Ala Val Met Asp Tyr Ser Gln Phe Ser Asn Leu

100 105 110Thr Ile Gln Gly Ile Leu Ser Thr Ile Lys Arg Tyr His Leu Thr Lys

115 120 125Gly Phe Phe Thr Pro

130(2) SEQ ID NO 738 information

Sequence properties:

(A) length: 82 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...82

(xi) sequence representation: SEQ ID NO 738: Met Lys Lys Thr Arg Ile Arg Lys Lys Ser Ala Leu Met Asn Gly Cys 151015 Trp Ala Glu Phe Asp Ser Val Phe Ser Ala Ile Val Pro Leu Glu Asp

20 25 30Leu Asn Lys Thr Ala Cys Ala His His Ala Leu Lys Ala Leu Gln Ala

35 40 45Thr Leu Lys Thr Thr Ile Trp Ala Leu Met Arg Gln Ser Trp Asn Arg

505560 Ser Gln Lys Asp Ser Ser Leu Gly Gly Ile Cys Gly Ile Leu Thr Arg 65707580 Met Phe (2) SEQ ID NO:739 information

Sequence properties:

(A) length: 105 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...105

(xi) sequence representation: SEQ ID NO:739: Trp Thr Leu Ala Lys Ile Arg Cys Val Lys Asn Phe Lys Glu Ala Ile 151015 Glu Gly Phe Thr Glu Lys Ile Lys Glu Ser Pro Asn Asp Ser Asn Ala

20 25 30Ile Asn Glu Ala Phe Asp Asn Leu Glu Thr Glu Leu Glu Arg Ala Thr35 40 45Glu Asn Leu Ses GLn Lys Ile Asp Pso Va1 Leu Glu Arg Asn Glu Asn

50 55 60Tyr Thr Gln Lys Ala Leu Glu Tyr Arg Glu Phe Leu Glu Ser Arg Lys65 70 75 80Glu Ser Phe Ile Val Asp Glu Lys Asn Pro Tyr Pro Glu Glu Val Ser

85 90 95Phe Asn Glu Trp Leu Leu Gly Gly Ile

100105 (2) SEQ ID NO 740 information

Sequence properties:

(A) length: 284 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...284

(xi) sequence representation: 740: Arg Pro Leu Ala Leu Ile Met Trp Trp Arg Asn Ile Asp Asn Arg Ile 151015 Ser Ile Lys Arg Val Val Asn Lys Pro Pro Arg Gly Leu Gly Lys Ile SEQ ID NO

20 25 30Thr Gln Glu Trp Ile Phe Ser Leu Leu Asp Glu Glu Gly Leu Asn Leu

35 40 45Glu Glu Ala Leu Lys Ile Gly Ala Phe Lys Asp Lys Leu Asn Pro Lys

50 55 60Asn Glu Tyr Ala Leu Lys Lys Phe Thr Ala Met Ile Gly Arg Leu Arg65 70 75 80Glu Ala Phe Glu Ile Ser Val Glu Lys Phe Cys Glu Arg Phe Leu Glu

85 90 95Glu Thr Asn Leu Leu Lys Ser Tyr Glu Lys Glu Asp Asn Tyr Glu Glu

100 105 110Arg Glu Gly Phe Val Lys Glu Leu Leu Ser Leu Val Lys Glu His Phe

115 120 125Lys Thr Asn Pro Thr His Ser Leu Leu Asp Phe Leu Asn Glu Ser Ala

130 135 140Leu Asp Val His Asn Thr Glu Asn Ala Gln Lys Val Ser Cys Met Ser145 150 155 160Val His Met Ser Lys Gly Leu Glu Phe Lys His Val Phe Val Ile Gly

165 170 175Leu Glu Glu Gly Phe Phe Pro His Arg Gly Phe Asn Gln Glu Ser Asp

180 185 190Leu Glu Glu Glu Arg Arg Leu Ala Tyr Val Ala Ile Thr Arg Ala Lys

195 200 205Glu Glu Leu Gln Leu Ser Tyr Val Lys Glu Arg Ser Tyr Phe Gly Arg

210 215 220Lys Ile Ser Cys Ser Pro Ser Val Phe Leu Glu Glu Ala Gln Leu Leu225 230 235 240Gln Gln Asp Lys Bro Pro Lys Gln Asn His Gln Lys Asp Thr Pro Ile

245 250 255Lys Val Gly Asp Leu Ile Lys His Lys Ile Phe Gly Thr Gly Glu Gly

260 265 270Phe Arg Arg Arg Lys Arg Leu Ala Ala Val Cys Ala

275280 (2) SEQ ID NO 741 information

Sequence properties:

(A) length: 242 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...242

(xi) sequence representation: 741 SEQ ID NO Asp Gly Ser Lys Lys Met Lys Ser Asn Lys Lys Ser Asn His Leu Arg 151015 Ala Ile Tyr Arg Ala Leu Val Ile Ala Ile Gly Leu Ala Val Ile Ile

20 25 30Val Phe Asn Tyr Phe Asn Arg Lys Asn Asn Asn Ala Arg Ser Ser Arg

35 40 45Arg Ala Cys Ser Cys Phe Phe Pro Pro Thr Gly Val Asn Leu Glu Lys

50 55 60Ile Gly Ser Phe Asp Thr Gly Ala Lys Leu Ile Val Leu Asn His Gln65 70 75 80Ser Leu Leu Asp Ile Ile Tyr Leu Glu Ala Tyr His Pro Ser Asn Ile

85 90 95Cys Trp Ile Ala Lys Lys Glu Leu Gly Glu Ile Pro Phe Tyr Gly His

100 105 110Ala Leu Thr Asp Thr Gly Met Ile Leu Ile Asp Arg Glu Asp Lys Lys

115 120 125Gly Ile Val Ser Leu Leu Lys Ala Cys Lys Glu Lys Leu Asp Gln Asn

130 135 140Arg Pro Leu Val Ile Phe Pro Glu Gly Thr Arg Gly Lys Gly Gly Glu145 150 155 160Lys Phe Leu Pro Phe Lys Gln Gly Ala Lys Ile Ile Ala Glu Lys Phe

165 170 175Gln Leu Lys Ile Gln Pro Met Val Leu Ile Asn Ser Ile LysIle Phe

180 185 190Asn Ser Lys Pro Leu Glu Ala Tyr Lys Ala Arg Thr Arg Leu val Met

195 200 205Leu Glu Ser Tyr Thr Pro Asp Phe Ser Ser Pro Thr Trp Tyr Glu Glu

210215220 Leu Gln Glu Arg Met Gln Lys Glu Tyr Leu Lys His Tyr His Glu Leu 225230235240 Asn Ala (2) SEQ ID NO:742 information

Sequence properties:

(A) length: 277 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...277

(xi) sequence representation: 742: Val Met Lys Thr Ser Asn Thr Lys Thr Pro Lys Pro Val Leu Ile Ala 151015 Gly Pro Cys Val Ile Glu Ser Leu Glu Asn Leu Arg Ser Ile Ala Ile SEQ ID NO

20 25 30Lys Leu Gln Pro Leu Ala Asn Asn Glu Arg Leu Asp Phe Tyr Phe Lys

35 40 45Ala Asn Phe Asp Asn Ala Asn Arg Thr Ser Leu Glu Ser Tyr Lys Glu

50 55 60Pro Gly Leu Glu Lys Gly Leu Glu Met Leu Gln Thr Ile Lys Asp Glu65 70 75 80Phe Gly Tyr Lys Ile Leu Thr Asp Val His Glu Ser Tyr Gln Ala Ser

85 9095Val Ala Ala Lys Val Ala Asp Ile Leu Gln Ile Pro Ala Phe Leu Cys

100 105 110Arg Gln Thr Asp Leu Ile Val Glu Val Ser Gln Thr Asn Ala Ile Val

115 120 125Asn Ile Lys Lys Gly Gln Phe Met Asn Pro Lys Asp Met Gln Tyr Ser

130 135 140Val Leu Lys Ala Leu Lys Thr Arg Asp Ser Ser Ile Gln Ser Pro Thr145 150 155 160Tyr Glu Thr Ala Leu Lys Asn Gly Val Trp Leu Cys Glu Arg Gly Ser

165 170 175Ser Phe Gly Tyr Gly Asn Leu Val Val Asp Met Arg Ser Leu Lys Ile

180 185 190Met Arg Glu Phe Ala Pro Val Ile Phe Asp Ala Thr His Ser Val Gln

195 200 205Me5 Pro Gly Gly Ala Asn Gly Lys Ser Ser Gly Asp Ser Ser Phe Pro

210 215 220Pro Ile Leu Pro Arg Ala Ala Ala Ala Val Gly Ile Asp Gly Leu Phe225 230 235 240Ala Glu Thr His Ile Asp Pro Lys Asn Ala Leu Ser Asp Gly Ala Asn

245 250 255Met Leu Lys Pro Asp Glu Leu Glu His Leu Val Thr Asn Met Leu Lys

260 265 270Ile Gln Asn Leu Phe

275(2) information of SEQ ID NO:743

Sequence properties:

(A) length: 313 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule:protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...313

(xi) sequence representation: SEQ ID NO 743: Gln Arg Asp His Gly Val Leu Tyr Leu Leu Asn Asn Thr Ile Ile Lys 151015 Phe Leu Ile Arg Arg Tyr Ile Met Leu Glu Asn Val Lys Lys Ser Leu

20 25 30Phe Arg Val Leu Cys Leu Gly Ala Leu Cys Leu Gly Gly Leu Ile Ala

35 40 45Glu Gln Asp Pro Lys Glu Leu Val Asn Leu Gly Thr Lys Ser Tyr Lys

50 55 60Glu Gln Asp Phe Thr Gln Ala Lys Lys Tyr Phe Glu Lys Ala Cys Asp65 70 75 80Leu Lys Glu Asn Ser Gly Cys Phe Asn Leu Gly Val Leu Tyr Tyr Gln

85 90 95Gly His Gly Val Glu Lys Asn Leu Lys Lys Ala Ala Ser Phe Tyr Ser

100 105 110Lys Ala Cys Asp Leu Asn Tyr Ser Asn Gly Cys His Leu Leu Gly Asn

115 120 125Leu Tyr Tyr Ser Gly Gln Gly Val Ser Gln Asn Thr Asn Lys Ala Trp

130 135 140Gln Tyr Tyr Ser Lys Ala Cys Asp Leu Lys Tyr Ala Glu Gly Cys Ala145 150 155 160Ser Leu Gly Gly Ile Tyr His Asp Gly Lys Val Phe Thr Arg Asp Phe

165 170 175Lys Lys Ala Val Glu Tyr Phe Thr Lys AlaCys Asp Leu Asn Asp Gly

180 185 190Asp Gly Cys Thr Ile Leu Gly Ser Leu Tyr Asp Ala Gly Arg Gly Thr

195 200 205Pro Lys Asp Leu Lys Lys Ala Leu Ala Ser Tyr Asp Lys Ala CVs Asp

210 215 220Leu Lys Asp Ser Pro Gly Cys Phe Asn Ala Gly Asn Met Tyr His His225 230 235 240Gly Glu Gly Ala Ala Lys Asn Phe Lys Glu Ala Leu Ala Arg Tyr Ser

245 250 255Lys Ala Cys Glu Leu Glu Asn Gly Gly Gly Cys Phe Asn Leu Gly Ala

260 265 270Met Gln Tyr Asn Gly Glu Gly Ala Thr Arg Asn Glu Lys Gln Ala Ile

275 280 285Glu Asn Phe Lys Lys Gly Cys Lys Leu Gly Ala Lys Gly Ala Cys Asp

290295300 Ile Leu Lys Gln Leu Lys Ile Lys Val 305310 (2) SEQ ID NO:744 information

Sequence properties:

(A) length: 529 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...529

(xi) sequence representation: 744 Met Set Ser Gly Leu Ile Tyr Ile Ser Leu Glu Val Leu Val Ala Cys 151015 Leu Ile Thr Ala Leu Ile Met Tyr Tyr Val Met Lys Lys Ile Tyr Tyr SEQ ID NO:744

20 25 30Ala Arg Gly Gln Ala Ile Leu Lys Gly Ala Ser Ala Lys Ala Lys Leu

35 40 45Met Glu Phe Gln Ala Lys Ser Phe Val Glu Ala Glu Glu Met Arg Met

50 55 60Lys Ser Gln Glu Cys Lys Leu Gln Gln Gln Tyr Glu Asn Lys Asn Leu65 70 75 80Gln Leu Gln Thr His Phe Asp Lys Lys Glu Ala His Leu Lys His Leu

85 90 95Glu Ala Gln His Lys Glu Phe Val Arg Asp Glu Lys Arg Tyr Leu Glu

100 105 110Lys Glu Lys Lys Glu Leu Glu Lys Glu Arg Gln Ile Leu Glu Gln Glu

115 120 125Arg Glu Asn Phe Lys Lys Gln Arg Ala Ile Cys Lys Glu Ala Gln Ala

130 135 140Lys Ala Leu Asp Ala Met Leu Asn Tyr Met Ala Tyr Thr Lys Asp Glu145 150 155 160Ile Lys Ser Met Ile Leu Glu Gln Leu Glu Glu Glu Leu Glu Ala Gln

165 170 175Lys Ser Ala Leu Ile Arg Arg Tyr Glu Lys Glu Ala Lys Glu Glu Gly

180 185 190Lys Lys Lys Ser Tyr Ala Ile Leu Ala Glu Ala Thr Ala Arg Phe Ala

195 200 205Gly Asp Tyr Ala Thr Glu Asn Leu Thr Ser Arg Ile Ala Leu Pro Cys

210 215 220Ser Asp Tyr Val Gly Arg Val Ile Gly Lys Asp Gly Lys Asn Ile Glu225 230 235 240Ala Phe Lys Lys Ile Ser Gly Val Asp Ile Glu Phe Ser Glu Asp Ser

245 250 255Ser Glu Leu Cys Leu Ser Ser Phe Asn Ile Tyr Arg Arg Glu Val Ala

260 265 2P0Ser Glu Thr Ile Lys Ile Leu Ile Glu Asp Gly Arg Ile Gln Pro Asn

275 280 285Arg Ile Glu Glu Val Tyr His Arg Val Ala Arg Asn Met Glu Lys Glu

290 295 300Leu Leu Ser Glu Gly Glu Ser Val Val Leu Glu Leu Glu Leu Gly Thr305 310 315 320Met Glu Asp Glu Leu Lys Ile Leu Ile Gly Lys Met Arg Tlyr Arg Phe

325 330 335Ser Phe Gly Gln Asn Ala Leu Gln His Ser Lys Glu Val Ala Leu Leu

340 345 350Ala Gly Leu Ile Ala Glu Gln Leu Gly Gly Asp Lys Lys Leu Ala Arg

355 360 365Arg Ala Gly Ile Leu His Asp Ile Gly Lys Ala Leu Thr Gln Glu Leu

370 375 380Gly Arg Asp His Val Asn Leu Gly Val Glu Val Cys Lys Arg His Lys385 390 395 400Glu Asp Pro Val Val Ile Asn Ala Ile Tyr Ala His His Gly His Glu

405 410 415Glu Ile Met Ser Val Glu Cys Ala Ser Val Cys Ala Ala Asp Ala Leu

420 425 430Ser Ala Gly Arg Pro Gly Ala Arg Arg Lys Ser Asp Glu Glu Tyr Ala

435 440 445Lys Arg Met Gln Ala Leu Glu Glu Ile Ala Leu Glu Phe Asp Gly Val

450 455 460Glu Lys Ala Tyr Ala Met Glu Ser Gly Arg Glu Leu Arg Val Ile Val465 470 475 480Lys Ser Asn Gln Val Arg Asp Asn Gln Val Pro Ile Ile Ala Arg Lys

485 490 495Ile Ala Lys Arg Ile Glu Glu Ser Thr Gln Tyr Val Gly Glu Val Gly

500 505 510Val Gln Val Val Arg Glu Asn Arg Phe Lys Thr Thr Ala Thr Leu Lys

515520525 Gln (2) SEQ ID NO 745 message

Sequence properties:

(A) length: 249 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...249

(xi) sequence representation: 745 SEQ ID NO. Met LysLys Gly Ser Leu Ala Ile Val Leu Gly Ser Leu Leu Ala Ser 151015 Gly Thr Phe Tyr Thr Ala Leu Ala Asp Gly Met Pro Met Lys Gln Gln

20 25 30His Asn Asn Met Gly Glu Ser Val Glu Leu His Phe His Tyr Pro Ile

35 40 45Lys Gly Lys Gln Glu Pro Lys Asn Asn His Leu Val Val Leu Ile Asp

50 55 60Pro Lys Ile Glu Ala Asn Lys Val Ile Pro Glu Asn Tyr Gln Lys Glu65 70 75 80Phe Glu Lys Ser Leu Phe Leu Gln Leu SerAsn Phe Leu Glu Arg Lys

85 90 95Gly Tyr Ser Val Ser Gln Phe Lys Asp Val Ser Glu Ile Pro Gln Asp

100 105 110Ile Lys Glu Lys Ala Leu Leu Val Leu Arg Met Asp Gly Asn Val Ala

115 120 125Ile Leu Glu Asp Ile Val Glu Glu Ser Asp Ala Leu Ser Glu Glu Lys

130 135 140Val Ile Asp Met Ser Ser Gly Tyr Leu Asn Leu Asn Phe Val Glu Pro145 150 155 160Lys Ser Glu Asp Ile Ile His Ser Phe Gly Ile Asp Val Ser Lys Ile

165 170 175Lys Ala Val Ile Glu Arg Val Glu Leu Arg Arg Thr Asn Ser Gly Gly

180 185 190Phe Val Pro Lys Thr Phe Val His Arg Ile Lys Glu Thr Asp His Asp

195 200 205Arg Ala Ile Lys Lys Ile Met Asn Gln Ala Tyr His Lys Val Met Ala

210 215 220His Ile Thr Lys Glu Leu Ser Lys Lys Mis Met Glu Arg Tlr Glu Lys225 230 235 240Val Ser Ser Glu Met Lys Lys Arg Lys

245(2) SEQ ID NO 746 message

Sequence properties:

(A) length: 119 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...119

(xi) sequence representation: 746 SEQ ID NO: Met Gln Asn Thr Phe Asn Tyr Thr Asn Asn Ala Leu Lys Asn Asn Ala 151015 Lys Leu Thr Pro ThrGlu Met Gln Ala Glu Gln Tyr Tyr Leu Gln Ser

20 25 30Thr Leu Gln Asn Ile Glu Lys Ile Val Met Leu Ser Gly Gly Val Ala

35 40 45Ser Asn Pro Lys Leu val Gln Ala Leu Glu Lys Met Gln Glu Pro Ile

50 55 60Thr Asn Pro Leu Glu Leu Val Glu Asn Leu Lys Asn Leu Glu Leu Gln65 70 75 80Phe Ser Gln Ser Gln Asn Ser Met Leu Ser Ser Leu Ser Ser Gln Ile

85 90 95Ala Gln Ile Ser Asn Ser Leu Asn Ala Leu Asp Pro Ser Ser Tyr Ser

100 105 110Lys Asn Val Ser Ser Met Tyr

115(2) SEQ ID NO 747 message

Sequence properties:

(A) length: 314 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...314

(xi) sequence representation: SEQ ID NO 747: Met Asp Leu Asp Lys Leu Lys Asp Tyr Arg Ala Leu Arg Asn Ala Ile 151015 Leu Arg Leu Leu Pro Tyr Leu Asp Ser Gly Ile Thr Glu Leu Ile Met

20 25 30Asn Lys Glu Lys Glu Ile Trp Leu Tyr Lys Leu Asn Gly Val Arg Glu

35 40 45Lys Val Phe Asp Glu Asn Leu Asp Lys Ala Phe Ile Leu Gly Phe Gly

50 55 60Glu Gln Leu Ala Ser Phe Arg Asp Leu Phe Phe Asn Ala Asn Tyr Pro65 70 75 80Thr Leu Asn Thr Ser Ile Pro Thr Ser Arg Tyr Arg Val Ser Met Asn

85 90 95His Phe Ala Ile Ser Ala Asp Asn Glu Leu Ser Leu Asn Ile Arg Val

100 105 110Pro Ser Asp Lys Lys Phe Asp Leu Lys Ala Phe Lys Leu Ser Ser Ile

115 120 125Cys Gln Tyr Asp Tyr Glu Tyr Leu Lys Asn Leu Met Ile Asp Gly Lys

130 135 140Asn Leu Leu Ile Ser Gly Gly Thr Gly Ser Gly Lys Thr Ser Phe Leu145 150 155 160Asn Ala Leu Ile Glu Phe Ile Pro Lys His Thr Arg Ile Val Ser Val

165 170 175Glu Asp Ser Glu Glu Leu Asp Leu Arg Ala Phe Glu Asn His Lys Ser

180 l85 190Leu Leu Val Asp Lys Thr Glu Ser Set Lys Phe Thr Tyr Glu Asn Ala

195 200 205Leu Asn Met Ala Met Arg Met Ser Pro Asp Arg Leu Met Val Gly Glu

210 215 220Ile AspThr Arg Asn Ser Met Leu Phe Leu Arg Phe Gly Asn Thr Gly 225 230 235 240His Lys Gly Met Val Ser Thr Leu His Ala Asp Ser Val His Gly Val

245 250 255Ile Glu Ala Ile Ala Leu Asn Leu Gln Met Asn Lys Ser Gly Leu Asp

260 265 270Val Asn Val Ala Lys Lys Phe Phe Lys Ser Set Val Asp Val Val Val

275 280 285Gln Ile Val Leu Asp Lys Ala Thr Asn Thr Arg Tyr Ile Gln Glu Ile

290295300 Leu Pro Ala Lys Asp Leu Arg Asp Ser Leu 305310 (2) SEQ ID NO:748 information

Sequence properties:

(A) length: 144 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...144

(xi) sequence representation: SEQ ID NO 748: Met Asn Ile Ser Val Asn Pro Tyr Leu Met Ala Val Val Phe Val Val 151015 Phe Val Leu Leu Leu Trp Ala Met Asn Val Trp Val Tyr Arg Pro Leu

20 25 30Leu Ala Phe Met Asp Asn Arg Gln Ala Glu Ile Lys Asp Ser Leu Ala

35 40 45Lys Ile Lys Thr Asp Asn Thr Gln Ser Val Glu Ile Gly His Gln Ile

5055 60Glu Thr Leu Leu Lys Glu Ala Ala Glu Lys Arg Arg Glu Met Leu Ala65 70 75 80Glu Ala Ile Gln Lys Ala Thr Glu Ser Tyr Asp Ala Val Ile Lys Gln

85 90 95Lys Glu Asn Glu Leu Asn Gln Glu Phe Glu Ala Phe Ala Lys Gln Leu

100 105 110Gln Asn Glu Lys Gln Ile Leu Lys Glu Gln Leu Gln Ala Gln Met Thr

115 120 125Val Phe Glu Asp Glu Leu Asn Lys Arg Val Ala Met Gly Leu Gly Ser

130135140 (2) information of SEQ ID NO:749

Sequence properties:

(A) length: 91 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...91

(xi) sequence representation: SEQ ID NO 749: Met Ala Ser Gly Leu Phe Glu Asn Asp Glu Ile Lys Asn Asn Lys Ala 151015 Arg Asp Phe Phe Tyr Ser His Ser Ser Leu Ile Val Phe Phe Leu Leu

20 25 30Leu Leu Gly Phe Gly Tyr Tyr Leu Gly Lys Leu Leu Phe Gly Gly Ser

35 40 45Ser Leu Glu Val Tyr Leu Asp Leu Arg Asp Lys His Glu Arg Leu Gln

5055 60Gln Glu Ile Thr Glu Leu Gln Ser Lys Asn Val Arg Leu Gln Lys Arg65 70 75 80Leu Phe Glu Leu Arg Glu Leu Arg Pro Arg Asp

8590 (2) SEQ ID NO 750 information

Sequence properties:

(A) length: 299 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...299

(xi) sequence representation: 750: Met Lys Lys Asn Ile Leu Asn Leu Ala Leu Val Gly Ala Leu Ser Ala 151015 Ser Phe Leu Met Ala Lys Pro Ala His Asn Ala Asn Asn Ser Thr His SEQ ID NO

20 25 30Asn Thr Lys Glu Thr Thr Asp Ala Ser Ala Gly Val Leu Ala Thr Val

35 40 45Asp Gly Arg Pro Ile Thr Lys Ser Asp Phe Asp Met Ile Lys Gln Arg

50 55 60Asn Pro Asn Phe Asp Phe Asp Lys Leu Lys Glu Lys Glu Lys Glu Ala65 70 75 80Leu Ile Glu Gln Ala Ile Arg Thr Ala Leu Val Glu Asn Glu Ala Lys

85 90 95Ala Glu Lys Leu Asn Gln Thr Pro Glu Phe Lys Ala Met Met Glu Ala

100 105 110ValLys Lys Gln Ala Leu Val Glu Phe Trp Ala Lys Lys Gln Ala Glu

115 120 125Glu Val Lys Lys Ile Gln Ile Pro Glu Lys Glu Met Gln Asp Phe Tyr

130 135 140Asn Ala Asn Lys Asp Gln Leu Phe Val Lys Gln Glu Ala His Ala Arg145 150 155 160His Ile Leu Val Lys Thr Glu Asp Glu Ala Lys Arg Ile Ile Ser Glu

165 170 175Ile Asp Lys Gln Pro Lys Ala Lys Lys Glu Ala Lys Phe Ile Glu Leu

180 185 190Ala Asn Arg Asp Thr Ile Asp Pro Asn Ser Lys Asn Ala Gln Asn Gly

195 200 205Gly Asp Leu Gly Lys Phe Gln Lys Asn Gln Met Ala Pro Asp Phe Ser

210 215 220Lys Ala Ala Phe Ala Leu Thr Pro Gly Asp Tyr Thr Lys Thr Pro Val225 230 235 240Lys Thr Glu Phe Gly Tyr His Ile Ile Tyr Leu Ile Ser Lys Asp Ser

245 250 255Pro Val Thr Tyr Thr Tyr Glu Gln Ala Lys Pro Thr Ile Lys Gly Met

260 265 270Leu Gln Glu Lys Leu Phe Gln Glu Arg Met Asn Gln Arg Ile Glu Glu

275 280 285Leu Arg Lys His Ala Lys Ile Val Ile Asn Lys

290295 (2) SEQ ID NO 751 information

Sequence properties:

(A) length: 305 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...305

(xi) sequence representation: 751: Met Ile Lys Ser Trp Thr Lys Lys Trp Phe Leu Ile Leu Phe Leu Met 151015 Ala Ser Cys Phe Gly His Leu Val Ala Thr Thr Gly Glu Lys Tyr Phe SEQ ID NO

20 25 30Lys Met Ala Asn Gln Ala Leu Lys Arg Gly Asp Tyr His Arg Ala Val

35 40 45Ala Phe Tyr Lys Arg Ser Cys Asn Leu Arg Met Gly Val Gly Cys Thr

50 55 60Ser Leu Gly Ser Met Tyr Glu Tyr Gly Asp Gly Val Asp Gln Asn Ile65 70 75 80Ser Lys Ala Val Phe Tyr Tyr Arg Arg Gly Cys Asn Leu Arg Asn His

85 90 95Leu Ala Cys Ala Ser Leu Gly Ser Met Tyr Glu Asp Gly Asp Gly Val

100 105 110Gln Lys Asp Phe Pro Lys Ala Ile Tyr Tyr Tyr Arg Arg Gly Cys His

115 120 125Leu Lys Gly Gly Val Ser Cys Gly Ser Leu Gly Phe Met Tyr Phe Asn

130 135 140Gly Thr Gly Val Lys Gln Asn Tyr Ala Lys Ala Leu Ser Phe Ser Lys145 150 155 160Tyr Ala Cys Ser Leu Asn Tyr Gly Ile Ser Cys Asn Phe Val Gly Tyr

165 170 175Met Tyr Lys Ser Ala Lys Gly Val Glu Lys Asp Leu Lys Lys Ala Leu

180 185 190Ala Asn Phe Lys Arg Gly Cys His Leu Lys Asp Gly Ala Ser Cys Val

195 200 205Ser Leu Gly Tyr Leu Tyr Glu Ala Gly Met Asp Val Lys Gln Asn Glu

210 215 220Glu Gln Ala Leu Asn Leu Tyr Lys Lys Gly Cys Ser Leu Lys Glu Gly225 230 235 240Ser Gly Cys His Asn Val Ala Val Met Tyr Tyr Thr Gly Lys Gly Ala

245 250 255Pro Lys Asp Leu Glu Lys Ala Thr Ser Tyr Tyr Lys Lys Gly Cys Ala

260 265 270Leu Gly Phe Ser Gly Ser Cys Lys Val Leu Glu Val Ile Gly Lys Glu

275 280 285Ser Asp Asn Leu Gln Asp Asp Ala Gln Asn Asp Thr Gln Asp Ser Val

290295300 Gln305(2) SEQ ID NO 752 information

Sequence properties:

(A) length: 502 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...502

(xi) sequence representation: 752 SEQ ID NO: Leu Lys Ile Phe Leu Val Ile Leu Ser Val Phe Phe Phe Asn Gly Cys 151015 Phe Gly Leu Ala Tyr Lys Thr Pro Ile Ser Asn Pro Pro Ile Ser Tyr

20 25 30Asp Pro Tyr Thr Thr Thr Ile Gly Ser Leu Tyr Ala Lys Asn Leu Lys

35 40 45Glu Asn Pro Lys His Ser Ala Ala Ile Leu Leu Glu Asp Gly Phe Asp

50 55 60Ala Leu Leu His Arg Val Gly Leu Ile Arg Met Ser Gln Lys Set Ile65 70 75 80Asp Met Gln Thr Tyr Ile Tyr Lys Asn Asp Leu Ser Ser Gln Val Ile

85 90 95Ala Lys Glu Leu Leu Asn Ala Ala Asn Arg Gly Val Lys Val Arg Ile

100 105 110Leu Leu Asp Asp Asn Gly Leu Asp Ser Asp Phe Ser Asp Ile Met Leu

115 120 125Leu Asn Phe His Lys Asn Ile Glu Val Lys Ile Phe Asn Pro Tyr Tyr

130 135 140Ile Arg Asn Lys Gly Leu Arg Tyr Phe Glu Met Leu AlaAsp Tyr Glu145 150 155 160Arg Ile Lys Lys Arg Met His Asn Lys Leu Phe Ile Val Asp Asn Phe

165 170 175Ala Val Ile Ile Gly Gly Arg Asn Ile Gly Asp Asn Tyr Phe Asp Asn

180 185 190Asp Leu Asp Thr Asn Phe Leu Asp Leu Asp Ala Leu Phe Phe Gly Gly

195 200 205Val Ala Ser Lys Ala Lys Glu Ser Phe Glu Asn Tyr Trp Arg Phe His

210 215 220Arg Ser Ile Pro Val Ser Leu Leu Arg Thr His Lye Arg Leu Lys Asn225 230 235 240Asn Val Lys Glu Ile Ala Lys Leu His Glu Lys Ile Pro Ile Ser Ala

245 250 255Glu Asp Ala Asn Glu Phe Glu Lys Lys Val Asn Asp Phe Ile Glu Arg

260 265 270Phe Gln Lys Tyr Gln Tyr Pro Ile Tyr Tyr Gly Asn Ala Ile Phe Leu

275 280 285Ala Asp Leu Pro Ala Lys Ile Asp Thr Pro Leu Tyr Ser Pro Ile Lys

290 295 300Ile Ala Phe Glu Lys Ala Leu Lys Asn Ala Lys Asp Ser Val Phe Ile305 310 315 320Ala Ser Ser Tyr Phe Ile Pro Gly Lys Lys Ile Met Lys Ile Phe Lys

325 330 335Asn Gln Ile Ser Lys Gly Ile Glu Leu Asn Ile Leu Thr Asn Ser Leu

340 345 350Ser Ser Thr Asp Ala Ile Val Val Tyr Gly Ala Trp Glu Arg Tyr Arg

355 360 365Asn Lys Leu Val Arg Met Gly Ala Asn Val Tyr Glu Ile Arg Asn Asp

370 375 380Phe Phe Asn Arg Gln Ile Lys Gly Arg Phe Ser Thr Lys His Ser Leu385 390 395 400His Gly Lys Thr Ile Val Phe Asp Asp Ala Leu Thr Leu Leu Gly Ser

405 410 415Phe Asn Ile Asp Pro Arg Ser Ala Tyr Ile Asn Thr Glu Ser Ala Val

420 425 430Leu Phe Asp Asn Pro Ser Phe Ala Lys Arg Val Arg Leu Ser Leu Lys

435 440 445Asp His Ala Gln Gln Ser Trp His Leu Val Leu Tyr Arg His Arg Val

450 455 460Ile Trp Glu Ala Thr Glu GluGly Ile Leu Ile His Glu Lys Asn Ser465 470 475 480Pro Asp Thr Ser Phe Phe Leu Arg Leu Ile Lys Glu Trp Ser Lys Val

485 490 495Leu Pro Glu Arg Glu Leu

500(2) SEQ ID NO:753 message

Sequence properties:

(A) length: 169 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...169

(xi) sequence representation: SEQ ID NO:753: Leu Lys Asn Leu Ser Thr Leu Leu Val Phe Leu Phe Phe Cys Leu Gly 151015 Cys Val Ser Asn Phe Asn Glu Asp Thr Tyr Thr Leu Asp Leu Val Leu

20 25 30Glu Lys Lys Ile Gln Ala Ser Arg Lys Gly Glu Ile Thr Gln Asp Asn

35 40 45Val Pro Ile Ile Thr Ala Ile Ala Thr His Leu Asn Asp Val Asp Ser

50 55 60Gly Thr Tyr Tyr Asp His Glu Tyr Phe Leu Val Glu Ile Phe Thr Gln65 70 75 80Asn Asn Asp Trp Ile Asp Asp Gly Tyr Ile Ser Tyr Glu Leu Phe Gly

85 90 95Thr Lys Pro Thr Gly Ser Glu Pro Leu Trp Val Arg Glu Ile Thr Arg

100 105 110Asp Glu Phe Asp Gly Ile Leu Glu Thr Thr ASn Arg Trp Ser Arg Ala

115 120 125Phe Leu Ile Ala Phe Asp Lys Leu Asp Tyr Leu Ala Val Gln Glu Ala

130 135 140Lys Leu Glu Leu Asp Ala Tyr Ser Leu Gly Lys Ile Val Phe Asn Phe145 150 155 160Ala Tyr Gln Val Pro Leu Pro Gln Phe

165(2) SEQ ID NO 754 message

Sequence properties:

(A) length: 511 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...511

(xi) sequence representation: 754 SEQ ID NO: Met Lys Lys Leu Leu Tyr Thr Met Leu Ala Leu Leu Leu Ile Gly Leu 151015 Leu Thr Ala Tyr Leu Ile Leu Phe Thr Glu Trp Gly Asn Lys Ile Ile

20 25 30Ala Ser Tyr Ile Glu Lys Lys Ile Asn Pro Asn Glu Arg Tyr Leu Ser

35 40 45Val Lys Thr Phe Lys Leu Arg Phe Asn Ser Leu Asp Phe Lys Ala Gln

50 55 60Ala Asn Asp Asp Ser Thr Leu Ile Leu Lys Gly Asp Phe Ser Leu Leu65 70 75 80Thr Gln Ser val Asn Leu Asp Tyr His Ile Asp Ile Lys Asn Leu Arg

85 90 95Ser Phe Lys Asp Leu Ile Pro Tyr Pro Leu Arg Gly Ala Ile Val Thr

100 105 110Ser Gly Asn Ile Lys Gly His Arg Lys Ala Leu Val Val Gln Gly Val

115 120 125Ser Asn Val Ala Gln Ser His Thr Ala Tyr Asn Ala Leu Leu Asp Asp

130 135 140Phe Lys Leu Ser His Leu Ser Leu Asn Ala Lys Asp Ala Asn Leu Glu145 150 155 160Asp Leu Leu Tyr Leu Ile Asn Arg Pro Ala Tyr Ala Asn Ala Lys Val

165 170 175Ser Leu Gln Ala Asp Phe Asn Ser Leu Lys Pro Leu Glu Gly His Leu

180 185 190Ile Leu Thr Ala Asn Asn Ala Leu Ile Asn Asn Ala Leu Ile Asn Gln

195 200 205I1e Phe His Leu Asn Leu Lys Asp Thr Leu Val Phe Asn Leu Ser His

210 215 220Ser Ser Asp Phe Lys Gly Asn Lys Ala Ile Ser Asp Thr Thr Leu Thr225 230 235 240Ser Pro Leu Val Asn Phe Thr Ala Leu Lys Ser Glu Tyr Ser Phe Pro

245 250 255Ala Leu Lys Leu Asn Ala Pro Tyr Thr Leu Glu Ile Pro His Leu Ala

260 265 270Lys Leu Gln Asn Ile Thr Asn His Pro Leu Lys Gly Ser Leu Thr Leu

275 280 285Lys Gly Asp Ile Glu Gln Ser Pro Lys Leu Leu Lys Val Ser Gly His

290 295 300Ser Asn Leu Leu Asp Gly Ala Leu Asp Phe Thr Leu Leu Asn Lys Asp305 310 315 320Leu Lys Ala Arg Phe Ser Asn Ile Ser Thr Ser Lys Ala Leu Asp Leu

325 330 335Phe His Tyr Pro Lys Phe Phe Gln Ser Ile Ala Asp Ala Asn Leu Asp

340 345 350Tyr Asp Leu Ile Ser Lys Gln Gly Val Leu Lys Ala Asn Leu Lys Asn

355 360 365Ala Arg Phe Leu Lys Asn Ala Phe Ser Asp Phe Leu Tyr Ser Ile Ser

370 375 380Arg Phe Asp Ile Thr Lys Glu Ile Tyr His Asp Ala Asn Leu Val Ser385 390 395 400Gln Ile Asn Gln Gln Arg Leu Leu Ser Asp Leu Ser Leu Lys Ser Pro

405 410 415Lys Thr Gln Leu Lys Ile His Asn Gly Leu Leu Asp Leu Asn Thr Lys

420 425 430Gln Met Asp Ile Leu Met Asp Ala Glu Ile Leu Lys Phe Ile Phe Lys

435 440 445Met Lys Leu Gln Gly Ser Met His Gln Pro Lys Phe Ser Leu Ile Leu

450 455 460Asn Glu Lys Ala Ile Gln Gln Asn Leu Gln Gln Gly Leu Lys Glu Ile465 470 475 480Leu Lys Asn Asp Thr Leu Lys Lys Gly Leu Asp His Leu Leu Lys Asp

485 490 495Asp Lys Leu Lys Glu Lys Leu Glu Lys Gly Leu Lys Gly Leu Phe

500505510 (2) information of SEQ ID NO:755

Sequence properties:

(A) length: 160 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...160

(xi) sequence representation: SEQ ID NO 755: Met Phe Gly Met Gly Phe Phe Glu Ile Leu Val Val Leu Ile Val Ala 151015 Ile Ile Phe Leu Gly Pro Glu Lys Phe Pro Gln Ala Val Val Asp Ile

20 25 30Val Lys Phe Phe Arg Ala Val Lys Lys Thr Leu Asn Asp Ala Lys Asp

35 40 45Thr Leu Asp Lys Glu Ile Asn Ile Glu Glu Ile Lys Lys Glu Thr Leu

53 55 60Glu Tyr Gln Lys Leu Phe Glu Asn Lys Val Glu Ser Leu Lys Gly Val65 70 75 80Lys Ile Glu Glu Leu Glu Asp Ala Lys Val Thr Ala Glu Asn Glu Ile

85 90 95Lys Ser Ile Gln Asp Leu Met Gln Asp Tyr Lys Arg Ser Leu Glu Thr

100 105 110Asn Thr Ile Pro Asn His Leu Asn Glu Glu Val Ser Asn Glu Glu Ala

115 120 125Leu Asn Lys Glu Val Ser Ser Asp Glu Ser Pro Lys Glu val Gln Leu

130135140 Thr Thr Asp Asn Asn Ala Lys Glu His Asp Lys Glu Lys Glu His Val 145150155160 (2) SEQ ID NO:756 information

Sequence properties:

(A) length: 80 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...80

(xi) sequence representation: 756: Met Leu Arg Ile Leu Ile Pro Leu Leu Ile Ile Val Trp Val Leu Trp 151015 Arg Leu Phe Leu Arg Gln Lys Pro His Lys Asp Asp His Arg Asp Asn of SEQ ID NO

20 25 30His Ser Tyr Thr Gln Gln Thr Pro Lys Glu Leu Glu Asp His Met Ile

35 40 45Val Cys Ser Lys Cys Gln Thr Tyr Val Ser Ser Lys Asp Ala Ile Tyr

505560 Ser Gly Ala Val Ala Tyr Cys Ser Glu Thr Cys Leu Lys Asp Lys Gly 65707580 (2) SEQ ID NO:757 information

Sequence properties:

(A) length: 214 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...214

(xi) sequence representation: SEQ ID NO:757: Leu Asp Gly Leu Lys Lys Glu Arg Gln Gly Phe Tyr Lys Gln Val His 151015 Tyr Leu Arg Ile Leu Ile Leu Ser Met Ser Phe Leu Asn Ile Leu Asn

20 25 30Ala Glu Asn Leu Ser Tyr Met Ser Ser Ser Tyr Gln Ile Gly Thr Val

35 40 45Phe Met Arg Pro Leu Asn Thr Asn Lys Leu Leu Gln Gly Ala Ser Ile

50 55 60Leu Gln Gly Tyr Glu Val Asn Pro Lys Asn Asp Trp Ala Tyr Ser Arg65 70 75 80Tyr Tyr Phe Phe Ile Asp Tyr Gly Asn Val Leu Phe Asn Asn Asp Ser

85 90 95Thr Leu Gln Ala Asn Met Phe Thr Tyr Gly Val Gly Gly Asp Phe Met

100 105 110Val Ala Tyr Ala Lys Asn Pro Ile Asn Arg Trp Ala Phe Phe Phe Gly

115 120 125Leu Gln Leu Ala Ala Asn Thr Trp Ile Leu Asn Asn Lys Val Lys Asp

130 135 140Leu Val Val Asn Thr Trp Asp Ser Leu Lys Asp Phe Asn Phe His Asn145 150 155 160Thr Tyr Phe Arg Ala Ile Gly Lys Phe Gly Val Gln Phe Arg Thr Ile

165 170 175Val Leu Tyr His Lys Val Asp Val Glu Ile Gly Met Lys Ile Phe Leu

180 185 190Thr Pro Glu Arg Arg Ser Leu Phe Glu Arg Ser Phe Leu Phe Phe Val

195 200 205Ser His Ser Trp His Phe

210(2) SEQ ID NO 758 information

Sequence properties:

(A) length: 111 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 111

(xi) sequence representation: 758 SEQ ID NO: Met Lys Pro Thr Asn Glu Pro Lys Lys Pro Phe Phe Gln Ser Pro Ile 151015 Val Leu Ala Val Leu Gly Gly Ile Leu Leu Ile Phe Phe Leu Arg Ser

20 25 30Phe Asn Ser Asp Gly Ser Phe Ser ASp Asn Phe Leu Ala Ser Ser Thr

35 40 45Lys Asn Val Ser Tyr His Glu Ile Ile Gln Leu Ile Ser Asn His Glu

50 55 60Val Gly Asn Val Ser Ile Gly Gln Thr Leu Ile Lys Ala Ser His Lys65 70 75 80Glu Gly Asn Asn Arg Val Ile Tyr Ile Ala Lys Arg Val Leu Ile Tyr

85 90 95Leu Ser Ala Phe Val Arg Arg Glu Lys Asn Gln Leu Phe Trp Phe

100105110 (2) SEQ ID NO:759 message

Sequence properties:

(A) length: 207 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ coarse

(B) Position: 1...207

(xi) sequence representation: SEQ ID NO:759: Met Leu Arg Val Leu Ser Val Gly Val Val Phe Ile Leu Leu Gly Cys 151015 Gln Phe Phe Asn Lys Thr Thr Leu His Leu Lys Tyr Lys Asp Tyr Pro

20 25 30Lys Asn Ser Pro Leu Lys Thr Ala Ser Thr Leu Thr Pro Pro Lys Ile

35 40 45Phe Phe Asn Ala His Phe Val Pro Pro Phe Tyr Gln Lys Glu Phe Lys

50 55 60Lys Ala Leu Ala Gln Gln Ile Ala Tyr Phe Leu Lys Asp Lys Ser Ala65 70 75 80Leu Thr Phe ASn Ile Ser Gly Asn Val Phe Phe Ser Phe Glu Glu Ser

85 90 95Pro Lys Asp Leu Lys Ala Ile Lys Glu Arg Leu Lys Lys Thr Ile Glu

100 105 110Pro Asn Thr Asp Pro Lys ALa Val Met Arg Phe Leu Asn Leu Gln Ala

115 120 125Ser Leu Ile Leu Glu Cys Val Pro Gln Thr Ala Cys Pro Phe Asp Thr

130 135 140Leu Leu Ile Pro Thr Ala Leu Ser Val Pro Ile Asp Tyr Ala Asn Arg145 150 155 160Leu Gly Asp Asn Pro Ser Leu Phe Pro Gln Glu Asp Lys Ser Tyr His

165 170 175Asn Ala Leu Ile Lys Ala Leu Asn Lys Ala Tyr Tyr Ser Leu Met Glu

180185 190Gly Leu Glu Lys Arg Leu Asn Ala Ile Glu Asn Ala Ala Trp Leu

195200205 (2) SEQ ID NO 760 information

Sequence properties:

(A) length: 175 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...175

(xi) sequence representation: 760: Met Lys Asn Gln Val Lys Lys Ile Leu Gly Met Ser Val Val Ala Ala 151015 Met Val Ile Val Gly Cys Ser His Ala Pro Lys Ser Gly Ile Ser Lys SEQ ID NO

20 25 30Ser Asn Lys Ala Tyr Lys Glu Ala Thr Lys Gly Ala Pro Asp Trp Val

35 40 45Val Gly Asp Leu Glu Lys Val Ala Lys Tyr Glu Lys Tyr Ser Gly Val

50 55 60Phe Leu Gly Arg Ala Glu Asp Leu Ile Thr Asn Asn Asp val Asp Tyr65 70 75 80Ser Thr Asn Gln Ala Thr Ala Lys Ala Arg Ala Asn Leu Ala Ala Asn

85 90 95Leu Lys Ser Thr Leu Gln Lys Asp Leu Glu Asn Glu Lys Thr Arg Thr

100 105 110Val Asp Ala Ser Gly Lys Arg Ser Ile Ser Gly Thr Asp Thr Glu Lys

115 120 125Ile Ser Gln Leu Val Asp Lys Glu Leu Ile Ala Ser Lys Met Leu Ala

130 135 140Arg Tyr Val Gly Lys Asp Arg Val Phe Val Leu Val Gly Leu Asp Lys145 150 155 160Gln Ile Val Asp Lys Val Arg Glu Glu Leu Gly Met Val Lys Lys

165170175 (2) SEQ ID NO:761 information

Sequence properties:

(A) length: 88 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...88

(xi) sequence representation: SEQ ID NO:761: Met Lys Lys Ile Val Val Ser Leu Cys Val Ala Leu Gly Phe Leu Ser 151015 Ala Asp Pro Ala Gln Ala Asn Lys Ala Ile Ser Asp Ala Asp Leu Ile

20 25 30Glu Glu Ile Arg Asp Leu Lys Lys Ile Ile Ser Ala Gln Asn Thr Glu

35 40 45Ile Asn Gln Leu Arg Lys Val Gln Glu Val Leu Ser Gly Gln Leu Gly

50 55 60Asp Met Arg Lys Asp Ile Leu Ser Thr Arg Asp Tyr Cys Ile Ser Leu65 70 75 80Arg Pro Tyr Ile Tyr Asn Trp Arg

85(2) SEQ ID NO 762 message

Sequence properties:

(A) length: 257 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...257

(xi) sequence representation: SEQ ID NO:762: Leu Asn Ser Gly Ser Asn Ala Ser Leu Tyr Gly Thr Ser Ala Gly Val 151015 Asp Ala Phe Leu Asn Gly Asn val Glu Ala Ile Val Gly Gly Phe Gly

20 25 30Ser Tyr Gly Tyr Ser Ser Phe Ser Asn Gln Ala Asn Ser Leu Asn Ser

35 40 45Gly Ala Asn Asn Ala Asn Phe Gly val Tyr Ser Arg Phe Phe Ala Asn

50 55 60Gln His Glu Phe Asp Phe Glu Ala Gln Gly Ala Leu Gly Ser Asp Gln65 70 75 80Ser Ser Leu Asn Phe Lys Ser Thr Leu Leu Gln Asp Leu Asn Gln Ser

85 90 95Tyr Asn Tyr Leu Ala Tyr Ser Ala Thr Ala Arg Ala Ser Tyr Gly Tyr

100 105 110Asp Phe Ala Phe Phe Arg Asn Ala Leu Val Leu Lys Pro Ser Val Gly

115 120 125Val Ser Tyr Asn His Leu Gly Ser Thr Asn Phe Lys Ser Asn Ser Gln

130 135 140Ser G1n Val Ala Leu Lys Asn Gly Ala Ser Ser Gln His Leu Phe Asn145150 155 160Ala Asn Ala Asn Va1 Glu Ala Arg Tyr Tyr Tyr Gly Asp Thr Ser Tyr

165 170 175Phe Tyr Leu His Ala Gly Val Leu Gln Glu Phe Ala His Phe Gly Ser

180 185 190Asn Asp Val Ala Ser Leu Asn Thr Phe Lys Ile Asn Ala Ala Arg Ser

195 200 205Pro Leu Ser Thr Tyr Ala Arg Ala Met Met Gly Gly Glu Leu Gln Leu

210 215 220Ala Lys Glu Val Phe Leu Asn Leu Gly Val Val Tyr Leu His Asn Leu225 230 235 240Ile Ser Asn Ala Ser His Phe Ala Ser Asn Leu Gly Met Arg Tyr Ser

245250255 Phe (2) SEQ ID NO:763 information

Sequence properties:

(A) length: 283 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...283

(xi) sequence representation: SEQ ID NO:763: Met Phe Glu Asp Phe Tyr Arg Thr Thr Leu Ser Phe Leu Arg Ser Leu 151015 Leu Leu Leu Leu Gly Leu Leu Leu Pro Phe Ser Leu Cys Ile Ala Asp

20 25 30Glu Tyr Ile Ser Ile Ser Asp Asp Trp Asp Glu Arg Ala Arg Asn Gln

35 40 45Trp Asp Glu Thr Ala Arg Asn His Lys Thr Tyr Tyr Phe Glu Asn Gly

50 55 60Leu Asp His Phe Asn Gln Gly Gln Tyr Lys Gln Ala Phe Lys Asp Phe65 70 75 80Lys Leu Ala Gln Glu Tyr Ser Ile Gly Leu Gly Asn Vat Tyr Leu Ala

85 90 95Lys Met Tyr Leu Glu Gly Lys Gly Val Lys Val Asp Tyr Lys Lys Ala

100 105 110Gln Phe Tyr Ala Gln Asn Ala Ile Lys Gly Tyr Gly Ser Gly Leu Leu

115 120 125Gly Gly Ala Leu Ile Leu Gly Arg Met Gln Ala Glu Gly Leu Gly Met

130 135 140Lys Lys Asp Leu Lys Gln Ala Leu Lys Thr Tyr Arg His Val Val Arg145 150 155 160Met Phe Ser Asn Lys Ser Ala Asn Phe Ala Asn Lys Phe Gly Ser Asn

165 170 175Leu Ala Glu Phe Thr Ser Met Leu Ile Gly Ser Arg Phe Ile Asp Leu

180 185 190Ser Gly Leu Ser Ala Asn Pro Ile Lys Phe Gly Asn Lys Phe Gly Ile

195 200 205Leu Val Lys Lys Ala Leu Gln Ile Lys ASp Asn Thr Leu Ser Trp Glu

210 215 220Asp Ile Ala Glu Ile Ser Ser Asn Ile Ile Leu Leu Lys Gln Gln Met225 230 235 240Gly Glu Ile Leu Tyr Arg Ile Gly Ile Ala Tyr Lys Glu Gly Leu Gly

245 250 255Thr Arg Lys Lys Lys Asp Arg Ala Lys Lys Phe Leu Gln Lys Ser Ala

260265 270Glu Phe Gly Tyr Glu Lys Ala Met Glu Ala Leu

275280 (2) SEQ ID NO 764 message

Sequence properties:

(A) length: 786 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...786

(xi) sequence representation: SEQ ID NO 764 Leu Cys Lys Ile Pro Leu Ser Leu Thr Leu Met Glu Ala Arg Ser Val 151015 Leu Thr Gln Glu Ile Arg Ser Phe Leu Pro Glu Thr Thr Thr Ser Leu

20 25 30Ser Leu Thr Ile Leu Glu Arg Ser Ile Cys Cys Leu Ile Lys Phe Leu

35 40 45Thr Leu Thr Ser Pro Cys Leu Thr Gln Gln Arg Pro Lys Ile Asn Ala

50 55 60Thr Asn Asn Asn Val Ser Val Ser Gln Gly Asn Leu Phe Ile Asn Ala65 70 75 80Ser Cys Val Gln Gln Ser Asp Pro Thr Thr Ala Ser Ala Thr Asn Pro

85 90 95Cys Thr Thr Ala Gln Asn Asn Ala Ser Ser Ser Asn Ala Ser Asn Asn

100 105 110Ala Pro Ile Ala Leu Asn Asn Asn Asp Glu Ser Leu Val Val Thr Ala

115 120125Asn Gly Phe Asn Phe Ser Gly Asn Ile Tyr Ala Asn Gly Val Val Asp

130 135 140Phe Ser Lys Ile Lys Gly Ser Ala Asn Val Lys Asn Leu Tyr Leu Tyr145 150 155 160Asn Asn Ala Gln Phe Gln Ala Asn Asn Leu Thr Ile Ser Asn Gln Ala

165 170 175Val Leu Glu Lys Asn Ala Ser Phe Val Thr Asn Asn Leu Asn Ile Gln

180 185 190Gly Ala Phe Asn Asn Asn Ala Thr Gln Lys Ile Glu Val Leu Gln Asn

195 200 205Leu Val Ile Ala Ser Asn Ala Ser Leu Ser Thr Gly Ile Tyr Gly Leu

210 215 220Glu Val Gly Gly Ala Leu Asn Asn Leu Gly Ala Ile His Phe Asn Leu225 230 235 240Glu Asn Ser Gln Thr Pro Val Asn Pro Leu Ile Gln Val Gly Gly Ile

245 250 255Ile Asn Leu Asn Thr Thr Gln Thr Pro Phe Met Asn Val Ser Val Ala

260 265 270Asn Gly Gly Thr Tyr Thr Leu Leu Lys Ser Ser Arg Tyr Ile Asp Tyr

275 280 285Asn Ile Asn Pro Asn Ser Leu Gln Ser Tyr Leu Lys Leu Tyr Thr Leu

290 295 300Ile Asn Ile Asn Gly Asn His Ile Glu Glu Lys Asn Gly Val Leu Thr305 310 315 320Tyr Leu Gly Gln Arg Val Leu Leu Gln Asp Lys Gly Leu Leu Leu Ser

325 330 335Val Ala Leu Pro Asn Ser Asn Asn Ala Ser Gln Asn Asn Ile Leu Ser

340 345 350Leu Ser Val Leu His Asn Gln Ile Lys Met Ser Tyr Gly Asn Lys Val

355 360 365Met Asp Phe Thr Pro Pro Thr Leu Gln Asp Tyr Ile Val Gly Ile Gln

370 375 380Gly Gln Ser Ala Leu Asn Gln Ile Glu Ala Val Gly Gly Asn Asn Ala385 390 395 400Ile Lys Trp Leu Ser Thr Leu Met Met Glu Thr Lys Glu Asn Pro Leu

405 410 415Phe Ala Pro Ile Tyr Leu Glu Asn His Ser Leu Asn Glu Ile Leu Gly

420 425 430Val Thr Lys Asp Leu Gln Asn Thr Ala Ser Leu Ile Ser Asn Pro Asn

435 440 445Phe Arg Asn Asn Ala Thr Ser Leu Leu Glu Met Ala Ser Tyr Thr Gln

450 455 460Gln Thr Ser Arg Leu Thr Lys Leu Ser Asp Phe Arg Ala Arg Glu Gly465 470 475 480Glu Ser Asn Phe Ser Glu Arg Leu Leu Glu Leu Lys Asn Lys Arg Phe

485 490 495Ser Asp Pro Asn Pro Ser Glu Val Phe Val Lys Tyr Ser Gln Leu Ser

500 505 510Lys His Pro Asn Asn Leu Trp Ile Gln Gly Val Gly Gly Ala Ser Phe

515 520 525Ile Ser Gly Gly Asn Gly Thr Leu Tyr Gly Leu Asn Val Gly Tyr Asp

530 535 540Arg Leu Val Lys Ser Val Ila Leu Gly Gly Tyr Val Ala Tyr Gly Tyr545 550 555 560Ser Gly Phe Asn Gly Asn Ile Met His Ser Leu Ala Asn Asn Val Asp

565 570 575Val Gly Met Tyr Ala Arg Ala Phe Leu Lys Arg Asn Glu Phe Thr Leu

580 585 590Ser Ala Asn Glu Thr Tyr Gly Gly Asn Ala Ser His Ile Asn Ser Ser

595 600 605Asn Ser Leu Leu Ser Val Leu Asn Gln Arg Tyr Asn Tyr Asn Thr Trp

610 615 620Thr Thr Ser Val Asn Gly Asn Tyr Gly Tyr Asp Phe Met Phe Lys Gln625 630 635 640Lys Ser Val Val Leu Lys Pro Gln Val Gly Leu Ser Tyr His Phe Ile

645 650 655Gly Leu Ser Gly Met Lys Gly Lys Met Gln Asn Pro Ala Tyr Gln Gln

660 665 670Phe Val Met His Ser Asn Pro Ser Asn Glu Ser Val Leu Thr Leu Asn

675 680 685Mer Gly Leu Glu Ser Arg Lys Tyr Phe Gly Lys Asn Ser Tyr Tyr Phe

690 695 700Val Thr Ala Arg Leu Gly Arg Asp Leu Leu Ile Lys Ala Lys Gly Asp705 710 715 720Asn Val Val Arg Phe Val Gly Glu Asn Thr Leu Leu Tyr Arg Lys Gly

725 730 735 Glu Ile Phe Asn Thr Phe Ala Ser Val Ile Thr Gly Gly Glu Met His

740 745 750Leu Trp Arg Leu Met Tyr Val Asn Ala Gly Val Gly Leu Lys Met Gly

755 760 765Leu Gln Tyr Gln Asp Leu Asn Ile Thr Gly Asn Val Gly Met Arg Val

770775780 Ala Phe785(2) SEQ ID NO:765 information

Sequence properties:

(A) length: 481 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...481

(xi) sequence representation: 765 SEQ ID NO: Met Phe Arg Lys Leu Ala Thr Set Val Ser Leu Ile Ser Leu Leu Ile 151015 Ser Asn Ala Leu Tyr Ala Lys Glu Ile Ser Glu Ala Asp Lys Val Ile

20 25 30Lys Ala Thr Lys Glu Thr Lys Glu Thr Lys Lys Glu Ala Lys Arg Leu

35 40 45Lys Lys Glu Ala Lys Gln Arg Gln Gln Ile Pro Asp Asn Lys Lys Pro

50 55 60Gln Tyr Val Ser Val Asp Asp Thr Lys Thr Gln Ala Leu Phe Asp Ile65 70 75 80Tyr Asp Thr Leu Asn Val Asn Asp Lys Ser Phe Gly Asp Trp Phe Gly

85 90 95Asn Ser Ala Leu Lys Asn Lys Thr Tyr Leu Tyr Ala Met Asp Leu Leu

100 105 110Asp Tyr Asn Asn Tyr Leu Set Ile Glu Asn Pro Ile Ile Lys Thr Arg

115 120 125Ala Met Gly Thr Tyr Ala Asp Leu Ile Ile Ile Thr Gly Ser Leu Glu

130 135 140Gln Val Asn Gly Tyr TyrAsn Ile Leu Lys Ala Leu Asn Lys Arg Asn145 150 155 160Ala Lys Pne Val Leu Lys Ile Asn Asp Lys Ile Pro Tyr Ala Gln Ala

165 170 175Thr Phe Leu Arg Val Pro Lys Arg Ser Asp Pro Asn Ala His Thr Leu

180 185 190Asp Lys Gly Ala Ser Ile Asp Glu Ser Lys Leu Phe Glu Gln Gln Lys

195 200 205Lys Met Tyr Phe Asn Tyr Ala Asn Asp val Ile Cys Arg Pro Asn Asp

210 215 220Glu Val Cys Ser Pro Leu Arg Asp Glu Met Val Ala Met Pro Thr Asn225 230 235 240Asp Ser Val Thr Gln Lys Pro Asn Ile Ile Ala Pro Tyr Ser Leu Tyr

245 250 255Arg Leu Lys Glu Thr Asn Asn Ala Asn Glu Ala Gln Pro Ser Pro Tyr

260 265 270Ala Thr Gln Thr Ala Pro Glu Asn Ser Lys Glu Lys Leu Ile Glu Glu

275 280 285Leu Ile Ala Asn Ser Gln Leu Ile Ala Asn Glu Glu Glu Arg Glu Lys

290 295 300Lys Leu Leu Ala Glu Lys Glu Lys Gln Glu Thr Glu Leu Ala Lys Tyr305 310 315 320Lys Leu Lys Asp Leu Glu Asn Gln Lys Lys Leu Lys Ala Leu Glu Ala

325 330 335Glu Leu Lys Lys Lys Asn Thr Lys Lys Pro Arg Val Val Glu Val Pro

340 345 350Ile Pro Pro Lys Thr Ser Asp Ser Asp Glu Thr Met Arg Val Ile Lys

355 360 365Glu Lys GluAsn Tyr Asn Gly Leu Leu Val Asp Lys Glu Thr Thr Ile

370 375 380Lys Arg Ser Tyr Lys Gly Thr Leu Ile Ser Glu Asn Ser Tyr Ser Lys385 390 395 400Lys Thr Pro Ile Asn Leu Glu Asp Leu Arg Ser Leu Glu Glu Glu Ile

405 410 415Lys Ser Tyr Tyr Val Lys Ser Asn Gly Leu Cys Tyr Ala Asn Gly Ile

420 425 430Asn Leu Tyr Val Lys Ile Lys Asn Asp Pro Tyr Lys Glu Gly Met Leu

435 440 445Cys Gly Tyr Glu Ser Val Gln Lys Leu Leu Ser Pro Leu Arg Asp Lys

450455460 Leu Lys Tyr Asp Lys Gln Lys Leu Gln Lys Ala Leu Leu Lys Asp Leu 465470475480 Lys (2) SEQ ID NO:766 information

Sequence properties:

(A) length: 59 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...59

(xi) sequence representation: 766: Leu Leu Ser Arg Ser Met Pro Lys Ile His Ala Val Phe Lys Ala Phe 151015 Ile Pro Ile Pro Phe Ala Leu Phe Ala Ile His Phe Val Val Leu Gly SEQ ID NO

20 25 30Ile Gly Ser Val Phe Asn Leu Asn Arg Ile Lys Asp Lys Lys Phe Ile

35 40 45Leu Arg Ala Lys Ile Ser His Ile Ala Gln Ala

5055 (2) SEQ ID NO 767 information

Sequence properties:

(A) length: 263 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...263

(xi) sequence representation: SEQ ID NO:767: Met Arg Lys Thr Ile Ser Ala Leu Phe Leu Ser Ala Cys Ile Gly Leu 151015 Ser Ser Val His Ala Ser Asn Ala Leu Ile Leu Gln Thr Asp Phe Ser

20 25 30Leu Lys Asp Gly Ala Val Ser Ala Met Lys Gly Val Ala Phe Ser Val

35 40 45Asp Ser Asn Leu Lys Ile Phe Asp Leu Thr His Glu Ile Pro Pro Tyr

50 55 60Asn Ile Trp Glu Gly Ala Tyr Arg Leu Tyr Gln Thr Ala Ser Tyr Trp65 70 75 80Pro Lys Gly Ser Val Phe Val Ser Val Val Asp Pro Gly Val Gly Thr

85 90 95Asn Arg Lys Ser Val Val Leu Lys Thr Lys Asn Gly Gln Tyr Phe Val

100 105 110Ser Pro Asp Asn Gly Thr Leu Thr Leu Val Ala Gln Thr Leu Gly Ile

115 120125Asp ger Val Arg Glu Ile Asp Glu Lys Ala Asn Arg Leu Lys Gly ser

130 135 140Glu Lys Ser Tyr Thr Phe His Gly Arg Asp Val Tyr Ala Tyr Thr Gly145 150 155 160Ala Arg Leu Ala Ser Gly Ala Ile Thr Phe Glu Gln Val Gly Pro Glu

165 170 175Leu Pro Ile Lys Val Val Glu Ile Pro Tyr Gln Lys Ala Lys Ala Thr

180 185 190Lys Gly Gly Val Lys Gly Asn Ile Pro Ile Leu Asp Ile Gln Tyr Gly

195 200 205Asn Val Trp Ser Asn Ile Ser Asp Lys Leu Leu Asn Gln Ala Gly Ile

210 215 220Lys Arg Asn Asp Thr Val Cys Val Thr Ile Leu Lys Ile Pro Arg Asn225 230 235 240Asn Thr Lys Gly Lys Cys Arg Met Ser Arg Ala Leu Ala Met Cys Gln

245 250 255Lys Ala Ser Arg Trp Ser Ile

260(2) SEQ ID NO 768 information

Sequence properties:

(A) length: 114 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...114

(xi) sequence representation: SEQ ID NO 768: Met Asn Ile Lys Thr His Ser Ser Asn Glu Lys Glu Arg Pne Val Arg 151015 Ile Glu Glu Asp Glu Lys Lys Glu Leu Phe Ala Glu Ala Thr Asn Glu

20 25 30Asn Pro His Gly Leu Ser Leu Met Ala Leu Ile Gly Val Leu Val Phe

35 40 45Gly Gly Ala Phe Leu Ala Leu Leu Val Pro Lys Ile Tyr Leu Ser Asn

50 55 60Asn Ile Tyr Tyr Ile Ser Arg Lys Ile Asn Thr Leu Glu Asp Gln Lys65 70 75 80Arg Leu Leu Leu Glu Glu Gln Gln Ile Leu Lys Asn Glu Leu Glu Lys

85 90 95Glu Arg Phe Lys Tyr Tyr Ile Glu Asn Ser Glu Asn Ile Gly Asp Ile

100105110 Ala Phe (2) SEQ ID NO:769 information

Sequence properties:

(A) length: 941 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...941

(xi) sequence representation: SEQ ID NO:769: Leu Gln His Lys Thr Ile Met Asp Lys Ile Ile Ile Gln Gly Ala Arg 151015 Glu Asn Asn Leu Lys Asn Ile Phe Leu Glu Ile Pro Lys Asn Gln Phe

20 25 30Val Val Phe Thr Gly Leu Ser GlySer Gly Lys Ser Thr Leu Ala Phe

35 40 45Asp Thr Leu Tyr Ala Glu Gly Gln Arg Arg Tyr Leu Glu Ser Leu Ser

50 55 60Ser Tyr Ala Arg Gln Phe Leu Asp Lys Val Gly Lys Pro Asn Val Asp65 70 75 80Lys Ile Glu Gly Leu Thr Pro Ala Ile Ala Ile Asp Gln Lys Thr Thr

85 90 95Ser Lys Asn Pro Arg Ser Thr Val Gly Thr Ile Thr Glu Ile Tyr Asp

100 105 110Tyr Leu Arg Leu Leu Phe Ala Arg Val Gly Glu Gln Phe Cys Pro Thr

115 120 125Cys Leu Glu Pro Ile Ser Ser Met Ser Ala Ser Asp Ile Ile Ser Gln

130 135 140Ile Cys His Leu Glu Glu Asn Ser Lys Ile Ile Ile Leu Ala Pro Ile145 150 155 160Ile Lys Asp Lys Lys Gly Ser Phe Asn Asp Lys Leu Glu Ser Leu Arg

165 170 175Leu Lys Gly Tyr Val Arg Ala Phe Val Asp Gly Val Met Val Arg Leu

180 185 190Asp Glu Glu Ile His Leu His Lys Thr Lys Lys His Thr Ile Glu Ala

195 200 205Val Val Asp Arg Val Val Ile Asn Ser Glu Asn Ala Ser Arg Ile Ala

210 215 220Ser Ala Val Glu Lys Ala Leu Lys Glu Ser Tyr Gly Glu Leu Glu Val225 230 235 240Glu Ile Leu Gln Asp Asn Ala Pro Ser Ile Arg Lys His Tyr Ser Glu

245 250 255His Lys Ala Cys Phe Lys Cys Lys Met Ser Phe Glu Glu Leu Glu Pro

260 265 270Leu Ser Phe Ser Phe Asn Ser Pro Lys Gly Ala Cys Glu Ser Cys Leu

275 280 285Gly Leu Gly Thr Lys Phe Ser Leu Asp Ile Ser Lys Ile Leu Asp Pro

290 295 300Asn Thr Pro Leu Asn Gln Gly Ala Ile Lys Val Ile Phe Gly Tyr Asn305 310 315 320Arg Ser Tyr Tyr Ala Gln Met Phe Glu Gly Phe Cys Thr Tyr Asn Gly

325 330 335Ile Asp Ser Ala Leu Cys Phe Asn Glu Leu Asn Lys Glu Gln Gln Asp

340 345 350Ala Leu Leu Tyr Gly Asn Gly Thr Glu Ile Ser Phe His Phe Lys Asn

355 360 365Ser Pro Leu Lys Arg Pro Trp Lys Gly Ile Ile Gln Ile Ala Tyr Asp

370 375 380Met Phe Lys Glu Gln Lys Asp Leu Ser Asp Tyr Met Ser Glu Lys Thr385 390 395 400Cys Ser Ser Cys Asn Gly His Arg Leu Lys Ala Ser Ser Leu Ser Val

405 410 415Gln Val Ala Gly Leu Lys Met Ala Asp Phe Leu Thr Lys Pro Ile Glu

420 425 430Glu Val Tyr His Phe Phe Asn Asp Pro Thr His Phe Asn Tyr Leu Asn

435 440 445Glu Gln Glu Lys Lys Ile Ala Glu Pro Ile Leu Lys Glu Ile Leu Glu

450 455 460Arg Val Phe Phe Leu Tyr Asp Val Gly Leu Gly Tyr Leu Thr Leu Gly465 470 475 480Arg Asp Ala Arg Thr Ile Ser Gly Gly Glu Ser Gln Arg Ile Aro Ile

485 490 495Ala Ser Gln Ile Gly Ser Gly Leu Thr Gly Val Leu Tyr Val Leu Asp

500 505 510Glu Pro Ser Ile Gly Leu His Glu Lys Asp Thr Leu Lys Leu Ile Asn

515 520 525Thr Leu Arg Asn Leu Gln Lys Lys Gly Asn Thr Leu Ile Val Val Glu

530 535 540His Asp Lys Glu Thr Ile Lys His Ala Asp Phe Val Val Asp Ile Gly545 550 555 560Pro Lys Ala Gly Arg His Gly Gly Glu Val Val Phe Ser Gly Ser Val

565 570 575Lys Asp Leu Leu Gln Asn Asn His Ser Thr Ala Leu Tyr Leu Asn Gly

580 585 590Thr Lys Lys Ile Glu Arg Pro Lys Phe Glu Pro Pro Lys Glu Lys His

595 600 605Phe Leu Glu Ile Lys Asn Val Asn Ile Asn Asn Ile Lys Asn Leu Ser

610 615 620Val Gln Ile Pro Leu Lys Gln Leu Val Cys Ile Thr Gly val Ser Gly625 630 635 640Ser Gly Lys Ser Ser Leu Ile Leu Gln Thr Leu Leu Pro Thr Ala Gln

645 650 655Thr Leu Leu Asn His Ala Lys Lys Asn Gln Ser Leu Asn Gly Val Glu

660 665 670Ile Val Gly Leu Glu Tyr Leu Asp Lys Val Ile Tyr Leu Asp Gln Ala

675 680 685Pro Ile Gly Lys Thr Pro Arg Ser Asn Pro Ala Thr Tyr Thr Gly Val

690 695 700Met Asp Glu Ile Arg Ile Leu Phe Ala Glu Gln Lys Glu Ala Lys Ile 705 710 715 720Leu Gly Tyr Ser Thr Ser Arg Phe Ser Phe Asn Val Lys Gly Gly Arg

725 730 735Cys Glu Lys Cys Gln Gly Asp Gly Asp Ile Lys Ile Glu Met His Phe

740 745 750Leu Pro Asp Val Leu Val Gln Cys Asp Ser Cys Lys Gly Ala Lys Tyr

755 760 765Asn Pro Gln Thr Leu Glu Ile Lys Val Lys Gly Lys Ser Ile Ala Asp

770 775 780Val Leu Asn Met Ser Val Glu Glu Ala Tyr Glu Phe Phe Ala Lys Phe785 790 795 800Pro Lys Ile Ala Val Lys Leu Lys Thr Leu Ile Asp Val Gly Leu Gly

805 810 815Tyr Ile Thr Leu Gly Gln Asn Ala Thr Thr Leu Ser Gly Gly Glu Ala

820 825 830Gln Arg Ile Lys Leu Ala Lys Glu Leu Ser Lys Lys Asp Thr Gly Lys

835 840 845Thr Leu Tyr Ile Leu Asp Glu Pro Thr Thr Gly Leu His Phe Glu Asp

850 855 860Val Asn His Leu Leu Gln Val Leu His Ser Leu Val Ala Leu Gly Asn865 870 875 880Ser Met Leu Val Ile Glu His Asn Leu Asp Ile Ile Lys Asn Ala Asp

885 890 895Tyr Ile Ile Asp Met Gly Pro Asp Gly Gly Asp Lys Gly Gly Lys Val

900 905 910Ile Ala Ser Gly Thr Pro Leu Glu Val Ala Gln Asn Cys Glu Lys Thr

915 920 925Gln Ser Tyr Thr Gly Lys Phe Leu Ala Leu GluLeu Lys

930935940 (2) SEQ ID NO:770 information

Sequence properties:

(A) length: 83 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...83

(xi) sequence representation: SEQ ID NO 770: Met Asn Tyr Asp Val Leu Met Gly Phe Leu Ala Leu Ile Leu Leu Ile 151015 Leu Trp Tyr Ala Tyr Gly Leu Arg Gln Tyr Leu Lys Leu Lys Asp Lys

20 25 30Asn Lys Arg Leu Lys Glu Lys Leu Gln Arg Cys Asn Cys Asn Ile Lys

35 40 45Ile Pro Ser Ile Leu Glu Met Ala His Lys Pro Ile Ile Met Asp Ile

505560 Lys Gly Glu Leu Leu Pro His Leu Thr Glu Ser Tyr Arg Lys Ser Lys 65707580 Phe Lys Glu (2) SEQ ID NO:771 information

Sequence properties:

(A) length: 279 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...279

(xi) sequence representation: SEQ ID NO:771: Met Arg Val Ile Ile Lys Phe Met Leu Ile Ser Leu Lys Thr Phe Leu 151015 Lys Ile Leu Leu Lys Ile Phe Leu Lys Thr Phe Gln Lys Ile Trp Ile

20 25 30 Val Cys Val Val Ile Trp Gly Leu Gly Cys Ser Phe Leu Asn Ala Asn

35 40 45Ser Val Gln Leu Glu Glu Thr Leu Arg Arg Asn Pro Lys Asn Leu Ile

50 55 60Trp Gln His Phe Lys Lys Lys Phe Lys Lys Ser Asn Thr Ile Pro Tyr65 70 75 80Ala Pro Asn Ser Arg Trp Lys Tyr Leu Gly Thr Ser Ile Gly Ile Leu

85 90 95Gly Val Ser Leu Val Ile Gly Ile Val Gly Leu Tyr Leu Met Pro Glu

100 105 110Ser Val Thr Asn Trp Asp Lys Glu Lys Phe Gly Val Lys Ser Trp Phe

115 120 125Glu Ash Val Arg Met Gly Pro Lys Leu Asp Asn Asp Ser Phe Ile Phe

130 135 140Asn Glu Ile Leu His Pro Tyr Phe Gly Ala Met Tyr Tyr Met Gln Pro145 150 155 160Arg Met Ala Gly Phe Ser Trp Met Thr Ser Ala Phe Phe Ser Phe Ile

165 170 175Thr Ser Thr Leu Phe Trp Glu Tyr Gly Leu Glu Ala Phe Val Glu Val

180 185 190Pro Ser Trp Gln Asp Leu Val Ile Thr Pro Leu Leu Gly Ser Ile Leu

195 200 205Gly Glu Gly Phe Tyr Gln Leu Thr Arg Tyr Ile Gln Arg Asn Glu Gly

210 215 220Lys Leu Phe Gly Ser Leu Phe Leu Gly Arg Leu Ala Ile Ala Leu Met225 230 235 240Asp Pro Ile Gly Phe Ile Ile Arg Asp Leu Gly Leu Gly Glu Ala Leu

245 250 255Gly Ile Tyr Asn Lys His Glu Ile Arg Ser Asn Leu Ser Pro Asn Gly

260 265 270Leu Asn Leu Thr Tyr Lys Phe

275(2) SEQ ID NO 772 information

Sequence properties:

(A) length: 177 amino acid residue

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...177

(xi) sequence representation: SEQ ID NO 772: Met Lys Leu Phe Asn Pro Arg Leu Ile Val Phe Ile Phe Ala Leu Leu 151015 Leu Gly Val Gly Phe Ser Val Pro Ser Leu Leu Glu Thr Lys Gly Pro

20 25 30Lys Ile Thr Leu Gly Leu Asp Leu Arg Gly Gly Leu Asn Met Leu Leu

35 40 45Gly Val Gln Thr Asp Glu Ala Leu Lys Asn Lys Tyr Leu Ser Leu Ala

50 55 60Ser Ala Leu Glu Tyr Asn Ala Lys Lys Gln Asn Ile Leu Leu Lys Asp65 70 75 80Ile Lys Ser Ser Leu Glu Gly Ile Ser Phe Glu Leu Leu Asp Glu Asp

85 90 95Glu Ala Lys Lys Leu Asp Ala Leu Leu Leu Glu Leu Gln Gly His Ser

100 105 110Gln Phe Glu Ile Lys Lys Glu Ala Glu Phe Tyr Ser Val Lys Leu Thr

115 120 125Pro Leu Glu Gln Glu Glu Leu Arg Lys Asn Thr Ile Leu Gln Val Ile

130 135 140Gly Ile Ile Arg Asn Arg Leu Asp Arg Phe Gly Leu Ala Glu Pro Val145 150 155 160Val Ile Gln Gln Gly Arg Val Glu Phe Arg Cys Asn Cys Pro Ala Leu

165170175 Arg (2) SEQ ID NO:773 message

Sequence properties:

(A) length: 436 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...436

(xi) sequence representation: 773 SEQ ID NO: Met Met Lys Phe Phe Leu Leu Lys Lys Phe Ser Glu Phe Leu Asn Thr 151015 Gln Thr His Phe Asn Leu Lys Arg Leu Asn Ala Ser Ser Phe Leu Leu

20 25 30Glu Thr Phe Ser Lys Glu Lys His Ala Phe Val Val Asp Leu SerAla

35 40 45Pro Tyr Ile Gly Leu Ser Lys Lys Pro Pro Glu Ser Val Leu Lys Asn

50 55 60Thr Leu Ala Leu Asp Phe Cys Leu Asn Lys Phe Thr Lys Asn Ala Lys65 70 75 80Ile Leu Gln Ala Asn Val Ile Asp Asn Asp Arg Ile Leu Glu Ile Lys

85 90 95Gly Ala Lys Asp Leu Ala Tyr Lys Ser Glu Thr Phe Ile Leu Arg Leu

100 105 110Glu Met Ile Pro Lys Lys Ala Asn Leu Met Ile Leu Asp Gln Glu Lys

115 120 125Cys Val Ile Glu Ala Phe Arg Phe Asn Asp Arg Val Ala Lys Asn Asp

130 135 140Ile Leu Gly Ala Leu Pro Pro Asn Ile Tyr Glu His Gln Glu Glu Asp145 150 155 160Leu Asp Phe Lys Gly Leu Leu Asp Ile Leu Glu Lys Asp Phe Leu Ser

165 170 175Tyr Gln His Lys Glu Leu Glu His Lys Lys Asn Gln Ile Ile Lys Arg

180 185 190Leu Asn Ala Gln Lys Glu Arg Leu Lys Glu Lys Leu Glu Lys Leu Glu

195 200 205Asp Pro Lys Thr Leu Gln Leu Glu Ala Lys Glu Leu Gln Thr Gln Ala

210 215 220Ser Leu Leu Leu Thr Tyr Gln His Leu Ile Asn Arg Arg Glu Asn Arg225 230 235 240Val Ile Leu Lys Asp Phe Glu Asp Lys Glu Cys Met Ile Glu Ile Asp

245 250 255Lys Ser Met Pro Leu Asn Ala Phe Ile Asn Lys Lys Phe Thr LeuSer

260 265 270Lys Lys Lys Lys Gln Lys Ser Gln Phe Leu Tyr Leu Glu Glu Glu Asn

275 280 285Leu Lys Glu Lys Ile Ala Phe Lys Glu Asn Gln Ile Asn Tyr Val Arg

290 295 300Asp Ala Ala Glu Glu Ser Val Leu Glu Met Phe Met Pro Val Lys Asn305 310 315 320Ser Lys Ile Lys Arg Pro Met Asn Gly Tyr Glu Val Leu Tyr Tyr Lys

325 330 335Asp Phe Lys Ile Gly Leu Gly Lys Asn Gln Lys Glu Asn Ile Lys Leu

340 345 350Leu Gln Asp Ala Arg Ala Asn Asp Leu Trp Met His Val Arg Asp Ile

355 360 365Pro Gly Ser His Leu Ile Val Phe Cys Gln Lys Asn Thr Pro Lys Asp

370 375 380Glu Val Ile Met Glu Leu Ala Lys Met Leu Ile Lys Met Gln Lys Asp385 390 395 400Ala Phe Asn Gly Tyr Glu Ile Asp Tyr Thr Gln Arg Lys Phe Val Lys

405 410 415Ile Ile Lys Gly Ala His Val Ile Tyr Ser Lys Tyr Arg Thr Ile Ser

420 425 430Leu Lys Asp Thr

435(2) SEQ ID NO 774 message

Sequence properties:

(A) length: 97 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...97

(xi) sequence representation: 774 SEQ ID NO: Met Gly Gln Thr Lys Glu Ile Ile Thr Thr Leu Leu Pro Leu Leu Val 151015 Leu Phe Leu Ile Phe Tyr Phe Leu Ile Val Arg Pro Gln Arg Gln Gln

20 25 30Gln Lys Lys His Lys Glu Met Ile Glu Gly Leu Thr Lys Gly Asp Lys35 40 45Ile Val Thr Gln Gly Gly Leu Ile Val Glu Val Leu Lys Ala Glu Ala

50 55 60Asn Phe Phe Ser Val Lys Leu Asn Asp Asp Thr Thr Ala Lys Leu Ser65 70 75 80Lys Asn Tyr Val Ala Phe Lys Leu Asp Glu Glu Thr Thr Pro Asn Asn

859095 Asn (2) SEQ ID NO:775 information

Sequence properties:

(A) length: 206 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: l.. 206

(xi) sequence representation: SEQ ID NO:775: Leu Lys Phe Gln Ile Val Ser Leu Leu Leu Ala Phe Leu Leu Ala Ser 151015 Cys Leu Pro Pro Lys Gly His His Ser Gly Leu Val Asn Met TyrIle

20 25 30Ala His Gln Gly Gln Ser Val Arg Thr Tyr Trp Arg Lys Val Asp Arg

35 40 45Gly Val Val Ala Lys His Asn Glu Thr Leu Lys Glu Asn Pro Lys Ile

50 55 60Lys Leu Lys Asp Pro Lys Gly Pro Leu Phe Met Leu Gly Ser Asn Arg65 70 75 80Phe Met Leu Leu Trp Lys Asn Arg Tyr Thr Leu Ala Lys Val Gln Ser

85 90 95Phe Lys Leu Glu Pro Gly Phe Tyr Tyr Leu Asp Ser Phe Ser Val Glu

100 105 110Thr Gln Lys Gly Ile Leu Gln Ser Ala Pro Gly Tyr Ser Tyr Thr Lys

115 120 125Asn Gly Tyr Asp Phe Lys Asn Asn Arg Pro Phe Phe Leu Ala Phe Glu

130 135 140Val Lys Pro Asp Ser Lys Ile Val Leu Pro Ser Val Glu Leu Ser Leu145 150 155 160Ile Lys Thr Pro Arg Gly Phe Leu Gly Val Phe Leu Phe Asp Asn Asn

165 170 175Glu Lys Gly Ala Asn Thr Pro Trp Ile Glu Gly Ser Leu Asn Leu Lys

180 185 190Leu Lys Asn Ala Ser Phe Lys Asp Ala Trp Glu Leu Glu Arg

195200205 (2) information of SEQ ID NO:776

Sequence properties:

(A) length: 533 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...533

(xi) sequence representation: SEQ ID NO 776 Met Arg Lys Val Ile Ile Met Asn Gly Tyr Leu Arg Val Lys Thr Pro 151015 Tyr Phe Leu Ala Ser Val Val Leu Thr Phe Trp Thr Phe Asn Ser Phe

20 25 30Met Ser Ala Lys Asp Lys His His Phe Leu Lys Lys Val Thr Thr Thr

35 40 45Glu Gln Lys Phe Ser Ser Ser Ala Pro Ile Ser Trp Gln Ser Glu Glu

50 55 60Val Arg Asn Ser Thr Ser Ser Arg Thr Val Ile Ser Asn Lys Glu Leu65 70 75 80Lys Lys Thr Gly Asn Leu Asn Ile Glu Asn Ala Leu Gln Asn Val Pro

85 90 95Gly Ile Gln Ile Arg Asp Ala Thr Gly Thr Gly Val Leu Pro Lys Ile

100 105 110Ser Val Arg Gly Phe Gly Gly Gly Gly Asn Gly His Ser Ash Thr Asn

115 120 125Mer Ile Leu Val Asn Gly Ile Pro Ile Tyr Gly Ala Pro Tyr Ser Asn

130 135 140Ile Glu Leu Ala Ile Phe Pro Val Thr Phe Gln Ser Val Asp Arg Ile145 150 155 160Asp Val Ile Lys Gly Gly Thr Ser Val Gln Tyr Gly Pro Asn Thr Phe

165 170 175Gly Gly Val Val Asn Val Ile Thr Lys Glu Ile Pro Lys Glu Trp Glu

180 185 190Asn Gln Ala Ala Glu Arg Ile Thr Phe Trp Gly ArG Ser Ser Asn Gly

195 200 205Asn Phe Val Asp Pro Lys Glu Lys Gly Lys Pro Leu Ala Gln Thr Leu

210 215 220Gly Asn Gln Met Leu Phe Ash Thr Tyr Gly Arg Thr Ala Gly Met Leu225 230 235 240Gly Lys Tyr Ile Gly Ile Ser Ala Gln Gly Asn Trp Ile Asn Gly Gln

245 250 255Gly Phe Arg Gln Asn Ser Pro Thr Lys Val Gln Asn Tyr Leu Leu Asp

260 265 270Ala Ile Tyr Lys Ile Asn Ala Thr Asn Thr Phe Lys Ala Tyr Tyr Gln

275 280 285Tyr Tyr Gln Tyr Asn Ser Tyr His Pro Gly Thr Leu Ser Ala Gln Asp

290 295 300Tyr Ala Tyr Asn Arg Phe Ile Asn Glu Arg Pro Asp Asn Gln Asp Gly305 310 315 320Gly Arg Ala Lys Arg Phe Gly Ile Val Tyr Gln Asn Tyr Phe Gly Asp

325 330 335Pro Asp Arg Lys Val Gly Gly Asp Phe Lys Phe Thr Tyr Phe Thr His

340 345 350Asp Met Ser Arg Asp Phe Gly Phe Ser Asn Gln Tyr Gln Ser Val Tyr

355 360 365Met Ser Gly Gln Asn Lys Ile Leu Pro Phe Lys Gly Lys Gly Glu Ile

370 375 380Ser Ala Lys Asn Pro Asn Cys Gly Leu Tyr Ser Tyr Ser Asp Thr Asn385 390 395 400Ser Pro Cys Trp Gln Phe Phe Asp Asn Ile Arg Arg Ser Val Val Asn

405 410 415Ala Phe Glu Pro Lys Leu Asn Leu Ile Val Asn Thr Gly Lys Val Lys

420 425 430Gln Thr Phe Asn Met Gly Met Arg Phe Leu Thr Glu Asp Leu Tyr Arg

435 440 445Arg Ser Thr Thr Arg Lys Asn Pro Ser Met Pro Asn Asn Gly Ser Gly

450 455 460Phe Asp Ala Gly Thr Ser Leu Asn Asn Phe Asn Asn Tyr Thr Ala Val465 470 475 480Tyr Ala Ser Asp Glu Ile Asn Phe Asn Asn Gly Met Leu Thr Ile Thr

485 490 495Pro Gly Leu Arg Tyr Thr Phe Leu Asn Tyr Glu Lys Lys Asp Ala Pro

500 505 510Pro Phe Lys Val Gly Gln Thr Pro Lys Thr Thr Lys Glu Arg Tyr Asn

515 520 525Gln Trp Asn Pro Ala

530(2) the message of SEQ ID NO:777

Sequence properties:

(A) length: 255 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...255

(xi) sequence representation: 777 SEQ ID NO: Met Lys Lys Ile Phe Leu Gly Met Ala Leu Ala Phe Ser Val Ser Met 151015 Ala Glu Lys Ser Gly Ala Phe Leu Gly Gly Gly Phe Gln Tyr Ser Asn

20 25 30Leu Glu Asn Gln Asn Thr Thr Arg Thr Pro Ser Ala Asn Asn Asn Thr

35 40 45Pro Ile Asn Thr Ser Met Phe Gly Asn Asn Gln Ala Ala Pro Ala Gln

50 55 60Glu Thr Pro Ser Val Ile Asn Thr Asn Asn Tyr Gly Gln Met Tyr Gly65 70 75 80Val Asp Ala Met Ala Gly Tyr Lys Trp Phe Phe Gly Lys Thr Lys Arg

85 90 95Phe Gly Phe Arg Thr Tyr Gly Tyr Tyr Ser Tyr Asn His Ala Asn Leu

100 105 110Ser Phe Val Gly Ser Lys Leu Gly Ile Met Asp Gly Ala Ser Gln Val

115 120 125Asn Asn Phe Thr Tyr Gly Val Gly Phe Asp Ala Leu Tyr Asn Phe Tyr

130 135 140Glu Ser Lys Glu Gly Tyr Asn Thr Ala Gly Leu Phe Val Gly Phe Gly145 150 155 160Leu Gly Gly Asp Ser Phe Ile Val Gln Gly Glu Ser Tyr Leu Lys Ser

165 170 175Gln Me5 Gln Ile Cys Asn Asn Thr Ala Gly Cys Ser Ala Ser Met Asn

180 185 190Thr Ser Tyr Phe Gln Met Pro Val Glu Phe Gly Phe Arg Ser Asn Phe

195 200 205Ser Lys His Ser Gly Ile Glu Val Gly Phe Lys Leu Pro Leu Phe Thr

210 215 220Asn Gln Phe Tyr Lys Glu Arg Gly Val Asp Gly Ser Val Asp Val Phe225 230 235 240Tyr Lys Arg Asn Phe Ser Ile Tyr Phe Asn Tyr Met Ile Asn Leu

2456250255 (2) SEQ ID NO 778 message

Sequence properties:

(A) length: 333 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...333

(xi) sequence representation: 778 SEQ ID NO: Met Leu Ile Ala Arg Phe Lys Lys Ala Leu Ile Ser Tyr Ser Leu Gly 151015 Val Leu Leu Val Ser Ser Leu Leu Gly Val Ala Asn Ala Ser Asn Gln

20 25 30Glu Ile Gln Val Lys Asp Tyr Phe Gly Glu Gln Thr Ile Lys Leu Pro

35 40 45Val Ser Lys Ile Ile Tyr Leu Gly Ser Phe Ala Glu Val Pro Ala Met

50 55 60Phe Asn Thr Trp Asp Arg Val Val Gly Ile Ser Asp Tyr Ala Phe Lys65 70 75 80Ser Asp Ile Val Lys Ala Thr Leu Lys Asp Pro Glu Arg Ile Lys Pro

85 90 95Met Ser Ser Asp His Val Ala Ala Leu Asn Val Glu Leu Leu Lys Lys

100 105 110Leu Ser Pro Asp Leu Val Val Thr Phe Val Gly Asn Pro Lys Ala Val

115 120 125Glu His Ala Lys Lys Phe Gly Ile Ser Phe Leu Ser Phe Gln Glu Lys

130 135 140Thr Ile Val Glu Val Met Glu Asp Ile Asp Ala Gln Ala Lys Ala Leu145 150 155 160Glu Val Asp Ala Ser Lys Lys Leu Ala Lys Met Gln Glu Thr Leu Asp

165 170 175Phe Ile Lys Glu Arg Leu Lys Asn Val Lys Lys Lys Lys Gly Val Glu

180 185 190Leu Phe His Lys Ala Asn Lys Ile Ser Gly His Gln Ala Leu Asp Ser

195 200 205Asp Ile Leu Glu Lys Gly Gly Ile Asp Asn Phe Gly Leu Lys Tyr Val

210 215 220Lys Phe GlyArg Ala Asp Ile Ser Val Glu Lys Ile Val Lys Glu Asn225 230 235 240Pro Glu IleIle Phe Ile Trp Trp Ile Ser Pro Leu Ser Pro Glu Asp

245 250 255Val Leu Asn Asn Pro Lys Phe Ser Thr Ile Lys Ala Ile Lys Asn Lys

260 265 270Gln Val Tyr Lys Leu Pro Thr Met Asp Ile Gly Gly Pro Arg Ala Pro

275 280 285Leu Ile Ser Leu Phe Ile Ala Leu Lys Ala His Pro Glu Ala Phe Lys

290 295 300Gly Val Asp Ile Asn Ala Ile Ile Lys Asp Tyr Tyr Lys Val Val Phe305 310 315 320Asp Leu Asn Asp Ala Glu Val Glu Pro Phe Leu Trp His

325330 (2) information SEQ ID NO 779

Sequence properties:

(A) length: 54 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...54

(xi) sequence representation: SEQ ID NO:779: Met Lys Lys Gln Ile Leu Thr Gly Val Leu Leu Ser Val Leu Ala Val 151015 Ser Ser Ala Tyr Ala His Lys Asp Lys Lys Asp Ala Lys Lys Pro Glu

20 25 30Leu Ser Ser Gln Leu Val Ala His Lys Asp Lys Lys Asp Ala Lys Lys

35 40 45Pro Lys Asn Ser Val Ala

50(2) SEQ ID NO 780 information

Sequence properties:

(A) length: 142 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...142

(xi) sequence representation: 780: Met Tyr Lys Leu Gly Ile Phe Leu Leu Ala Thr Leu Leu Ser Ala Asn 151015 Thr Gln Lys Val Ser Asp Ile Ala Lys Asp Ile Gln His Lys Glu Thr SEQ ID NO

20 25 30Leu Leu Lys Lys Thr His Glu Glu Lys Asn Gln Leu Asn Ser Arg Leu

35 40 45Ser Ser Leu Gly Glu Ala Ile Arg Ser Lys Glu Leu Gln Lys Val Glu

50 55 60Ile Glu Arg Gln Met Val Ala Leu Lys Lys Ser Leu Glu Lys Asn Arg65 70 75 80Asn Glu Ser Leu Val Gln Glu Lys Val Leu Thr Asn Tyr Arg Lys Ser

85 90 95Leu Asp His Leu Gln Lys Gln Arg Ser Phe Leu Gln Lys Arg Val Phe

100 105 110Asp Thr Leu Leu Glu Asp Phe Leu Phe Ser Gln Ala Leu Lys Gly Gln

115 120 125Asn Leu Ala Ser Ser Asn Asp Val Ile Leu Leu Ser Gly Val

130135140 (2) SEQ ID NO 781 message

Sequence properties:

(A) length: 197 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...197

(xi) sequence representation: 781: Met Asp Lys Asn Asn Asn Asn Asn Leu Arg Leu Ile Leu Ala Ile Ala 151015 Leu Ser Phe Leu Phe Ile Ala Leu Tyr Ser Tyr Phe Phe Gln Glu Pro SEQ ID NO

20 2530Asn Lys Thr Thr Thr Glu Thr Thr Lys Gln Glu Thr Thr Asn Asn His

35 40 45Thr Ala Thr Ser Pro Thr Ala Ser Asn Thr Ile Thr Gln Asp Phe Ser

50 55 60Val Thr Gln Thr Ile Pro Gln Glu Ser Leu Leu Ser Thr Ile Ser Phe65 70 75 80Glu His Ala Lys Ile Glu Ile Asp Ser Leu Gly Arg Ile Lys Gln Val

85 90 95Tyr Leu Lys Asp Lys Lys Tyr Leu Thr Pro Lys Glu Lys Gly Phe Leu

100 105 110Glu His Val Ser His Leu Phe Ser Ser Lys Glu Asn Ser Gln Pro Ser

115 120 125Leu Lys Glu Leu Pro Leu Leu Ala Ala Asp Lys Leu Lys Pro Leu Glu

130 135 140Val Arg Phe Leu Asp Pro Thr Leu Asn Asn Lys Ala Phe Asn Thr Pro145 150 155 160Tyr Ser Ala Ser Lys Thr Thr Leu Gly Pro Asn Glu Gln Leu Val Leu

165 170 175Thr Gln Asp Leu Gly Thr Leu Ser Ile Ile Lys Thr Leu Thr Phe Tyr

180 185 190Asp Asp Leu His Tyr

195(2) SEQ ID NO:782 information

Sequence properties:

(A) length: 259 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...259

(xi) sequence representation: 782: Met Ala Cys Trp His Lys Arg Leu Ala Val Gly Cys Cys Ile Val Leu 151015 Leu Ser Cys Val Met Ser Ala Asn Asn Val Ser Ile Val Arg Asp Asp SEQ ID NO

20 25 30Pro Pro Leu Asp Pro Thr Leu Pro Ala Trp Ile Tyr Ser Val Ala Leu

35 40 45Leu Lys Val Tyr Phe Ser Asp Gly Thr Tyr Lys Glu Gly Tyr Ala Thr

50 55 60Leu Leu Glu Asn Gly Arg Tyr Ile Ala Ser Ser Glu Thr Leu Tyr Ser65 70 75 80Ash Gly Leu Tyr Pro Lys Met Ile Leu Ala Lys Met Gln Asp Ser Ser

85 90 95Ala Lys Glu Leu Ile Cys Ile Ala Ser Leu His Leu Glu Ala Met Asp

100 105 110Arg Asp Gln Gly Leu Ser Leu Leu Lys Thr Ala Asp Phe Arg Asp Asp

115 120 125Tyr Cys His Lys Arg Glu Glu Ser Tyr Tyr His Ala Arg Ile Tyr Ala

130 135 140Lys Tyr Ala Gln Thr Phe His Ser Asn Pro Tyr Thr Asn Gln Lys Thr145 150 155 160Pro Thr Ser Asp Leu Tyr Tyr Pro Ala Leu Asn Glu Gly Asn Ser Phe

165 170 175Ser Ile Gln Thr Thr Asp Ile Ser Val Ala Glu Leu Leu Lys Ser Lys

180 185 190Lys Phe Leu Ser Leu Asp Ala Ser Phe Lys Lys Giy Ser Val Leu Trp

195 200 205Gly Gly Arg Pro Tyr Phe Ser Glu Val Gly Glu Phe Met Gly Met Ala

210 215 220Ser Ser Thr Leu Glu Asn Gln Glu Ser Leu Val Ile Ile Pro Lys Glu225 230 235 240Lys Ile Ala Arg Phe Leu Ser Ala Leu Lys Asn Gln Asn Ile Phe Pro

245250255 Asn Ile Pro (2) SEQ ID NO:783 information

Sequence properties:

(A) length: 668 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...668

(xi) sequence representation: 783: Met Lys Asn Gln His Lys Asn Pro Leu Thr Lys Ala Leu Met Lys Thr 151015 Tyr Pro Tyr Asn His Phe Leu Phe Phe Cys Phe Ile Leu Gly Ala Phe SEQ ID NO

20 25 30Leu Leu Gly Leu Leu Ser Pro Ala Tyr Ala Leu Ser Ile Ile Thr Thr

35 40 45Lys Glu Ile Asp Ala Asn Leu Leu Asn Gly Ala Ile Glu Ser Arg Val

50 55 60val Leu Gly Lys Arg Val Phe Lys Val Glu Ala His Gly Phe Tyr Phe65 70 75 80Arg Asn Ash Ala Thr Asn Ser Ile Asp Ile Glu Ile Thr Ser Leu Leu

85 90 95Arg Asp Asn Gln Ser Phe Pro Leu Thr Ser Ser Ala Lys Thr Ser Leu

100 105 110Lys Ile Pro Pro Asn Ala Lys Ile Lys Lys Ser Thr Ile Leu Val Leu

115 120 125Lys Gly Glu Asn Ala Glu Glu Val Ala Lys Ile Leu Gly Val Ser Lys

130 135 140Glu Glu Tyr Gln Lys Leu Glu Asn Ile Ala Gln Thr Lys Ala Ala Asn145 150 155 160Asp Pro Met Tyr Ala Asn Thr Pro Phe Ser Asn Gly Ser Asp Ser Ser

165 170 175Phe Tyr Asp Asn Asn Pro Asn Ser Pro Ser Asn Asn Ala Ile Asn Gly

180 185 190Lys Asp Gly Ala Asn Gly Ser Asn Gly Tyr Gly Ala Asn Gly Asn Asp

195 200 205Gly Val Asn Gly Ile Ser Gly Ser Asn Gly Ala Asn Gly Ser His Ssr

210 215 220Asn Asn AsnAla Ile Gly Ser Gly Ile Asp Thr Asp Gly Val Leu Gly225 230 235 240Val Asp Gly Val Asn Gly Ser Ser Ser Ser Ser Gly Gly Ser Val Gly

245 250 255Gly Tyr Glu Asn Asn Phe Thr Asn His Gly Ser Thr Asn Asn Asn Thr

260 265 270Gly Gly Tyr Asp Asn Phe Asn Asn Gly Ser Ser Ser Gly Gly Ser Leu

275 280 285Gly Asn Gly Gly Leu Phe Pro Ile Pro Phe Gly Asn Gly Asp Thr Asn

290 295 300Asn Ser Asn Asn Ser Thr Asn Thr Thr Ser Pro Thr Asn Gly SerSer305 310 315 320Ser Asn Asn Ala Thr Asn Pro Ser Ser Gln Glu Asn Asn Tyr Ser Ser

325 330 335Gln Tyr Cys Lys Val Pro Glu Leu Ser Pro Asn Asn Thr Met Lys Leu

340 345 350Asp Val Ile Ala Lys Asp Gly Ser Cys Ile Ser Met Asn Ala Leu Arg

355 360 365Asp Asp Thr Lys Cys Ala Tyr Arg Tyr Asp Phe Glu Ala Gly Lys Ala

370 375 380Ile Lys Gln Thr Gln Tyr Tyr Tyr Val Asp Arg Glu Asn Lys Thr Gln385 390 395 400Asn Ile Gly Gly Cys Val Asp Leu Gln Gly Ala Gln Tyr Ala Met Gln

405 410 415Leu Tyr Lys Asp Asp Ser Lys Cys Ala Leu Gln Thr Thr Ser Asp Lys

420 425 430Gly Tyr Gly Met Gly Lys Thr Gln Thr Phe Gln Thr Glu Ile Val Phe

435 440 445Arg Gly Met Asp Asn Leu Ile His Val Ala Val Pro Cys Ser Asp Tyr

450 455 460Ala Arg Val Gln Asp Arg Ile Val Arg Tyr Glu Lys Asn Asp Lys Thr465 470 475 480Gln Thr Leu Thr Pro Ile Val Asp Gln Tyr Tyr Asn Asp Pro Asn Asn

485 490 495Pro Asn Lys Gln Glu Ile Leu Asn Arg Gly Ile Ala Thr Gln Leu Ser

500 505 510Ser Gln Tyr Gln Glu Phe Ala Cys Gly Gln Trp Glu Tyr Asn Asp Ala

515 520 525Lys Leu Glu Ala Lys Arg Pro Thr Met Leu Lys SerTyr Asn Lys Leu

530 535 540Asn Gly Glu Trp Val Glu Val Thr Pro Cys Asn Phe Glu Ala Gly Ile545 550 555 560Lys Ser Gly Ala Val Val Ser Pro Tyr Val Met Gly Val Pro Ser Ser

565 570 575Lys Val Leu Ser Asp Ile Thr Thr Ser His Tyr Phe Arg Ile Glu Arg

580 585 590Lys Asn Tyr Gly Glu Arg Glu Gln Cys Gln Lys Leu Tyr Gly Val Asn

595 600 605Arg Cys Gln Pro Gln Tyr Ser Ile Leu Ile Leu Val Ser Pro Ile Gly

610 615 620Ala Pro Leu Thr Lys Pro Leu Pro Pro Lys Pro Leu Asn Leu Ile Tyr625 630 635 640Ala Gln Pro Lys Ile Met Lys Asn Thr Pro Gln Pro Ile Ile Leu Ser

645 650 655Pro Leu Lys Pro Pro Ser Thr Gly Leu Lys Ala Phe

660665 (2) SEQ ID NO 784 information

Sequence properties:

(A) length: 328 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...328

(xi) sequence representation: SEQ ID NO 784: Met Thr Tyr Lys Glu Arg Leu Ile His Glu Lys Ile Leu Asn Gln Asn 151015 Asp Lys Gly Phe Lys Thr Glu Leu Arg Ile Leu Ser Val Phe Ile Val

20 25 30Glu Phe Leu Val Asn Ile Leu Gly Phe Met Leu Ala Lys Met Pro His

35 40 45Phe Trp Phe Leu Arg Cys Val Lys Ala Leu Ala Trp Leu Met Lys Thr

50 55 60Phe Asp Arg Arg Arg Tyr Phe Asp Ala Lys Ala Asn Leu Asp Phe Val65 70 75 80Phe Gly Asp Ser Lys Ser Glu Glu Glu Lys Lys Arg Ile Ile Lys Lys

85 90 95Gly Tyr Glu Asn Phe Ala Phe Ile Ile Leu Glu Thr Ile Arg Val Ile

100 105 110Phe Ile Pro Lys Asp Glu Tyr Asp Ala Arg Phe Thr Leu Ile Asn Glu

115 120 125Glu Asn Val Trp Lys Ser Leu Asn Lys Glu Gly Gln Ala Ile Thr Leu

130 135 140Cys Met His Phe Gly Tyr Trp Glu Ala Val Gly Thr Thr Leu Ala Gln145 150 155 160Tyr Tyr Glu Asn Tyr Gly Arg Gly Cys Leu Gly Arg Leu Thr Lys Phe

165 170 175Ala Pro Ile Asn His Met Ile Met Ser Arg Arg Glu Ala Phe Gly Val

180 185 190Arg Phe Val Asn Lys Ile Gly Ala Met Lys Glu Leu Ile Lys Met Tyr

195 200 205ASn Gln Gly Asn Gly Leu Val Gly Ile Leu Val Asp Gln Asn Val Val

210 215 220Pro Lys Asp Gly Val Val Val Lys Phe Phe Asn Lys Asp Ala Thr Thr225 230235 240Thr Thr Ile Ala Ser Ile Leu Ser Arg Arg Tyr Asn Ile Asp Ile Gln

245 250 255Pro Val Phe Ile Asp Phe Asn Asp Asp Tyr Ser His Tyr Thr Ala Thr

260 265 270Tyr Tyr Pro Ser Ile Arg Ser Gln Ile Thr Asp Asn Ala Gln Asn Asp

275 280 285Ile Leu Glu Cys Thr Gln Ala Gln Ala Ser Leu Cys Glu Glu Val Ile

290 295 300Arg Asn His Pro Glu Ser Tyr Phe Trp Phe His Arg Arg Phe Lys Ser305 310 315 320Thr His Pro Glu Ile Tyr Gln Arg

325(2) SEQ ID NO 785 message

Sequence properties:

(A) length: 138 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...138

(xi) sequence representation: SEQ ID NO 785: Met Leu Tyr Leu Arg Lys Glu Asn Gly Val Arg Thr Leu Ile Ser Leu 151015 Gly Ile Leu Leu Ser Val Leu Asn Gly Asp Asp Leu Arg Leu Tyr Ser

20 25 30Lys Pro Leu Val Tyr Ser Ala Gly Ser Gly Ile Ile Gly Ile Asp Ile

35 40 45Asp Lys Arg Thr Phe Tyr Lys Arg Ala Phe Ala Phe Thr Met Lys Ser

50 55 60Leu Phe Gly Glu Asn Leu Leu Leu Phe Val Lys Leu Lys His Ser Ala65 70 75 80Leu Met Ser Lys His Met Lys Gly Pro Leu Glu Asn Arg His His His

85 90 95Ser Phe Ala Lys Asn Tyr Glu Lys Ala Val Asn Gly Cys Gln Lys Tyr

100 105 110Val His Ile Lys Leu Pro Glu Gly Ala Pro Ser Asn Phe Gln Ser Gly

115 120 125Ser Tyr Met Ala Thr Met Val Met Arg Phe

130135 (2) information SEQ ID NO:786

Sequence properties:

(A) length: 328 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...328

(xi) sequence representation: SEQ ID NO 786: Met Arg Lys Val Leu Tyr Ala Leu Met Gly Phe Leu Leu Val Phe Ser 151015 Ala Leu Lys Ala Asp Asp Phe Leu Glu Glu Ala Asn Glu Thr Ala Pro

20 25 30Ala Asn Leu Asn His Pro Met Gln Asp Leu Asn Ala Ile Gln Gly Ser

35 40 45Phe Phe Asp Lys Asn Arg Ser LysMet Ser Asn Thr Leu Asn Ile Asp

50 55 60Tyr Phe Gln Gly Gln Thr Tyr Lys Ile Arg Leu Arg Tyr Ala Met Ala65 70 75 80Thr Leu Leu Phe Phe Ser Lys Pro Ile Ser Asp Phe Val Leu Gly Asp

85 90 95Lys Val Gly Phe Asp Ala Lys Ile Leu Glu Ser Asn Asp Arg Ile Leu

100 105 110Leu Ile Lys Pro Leu Gln Ile Gly Val Asp Ser Asn Ile Ser Val Ile

115 120 125Asp Ser Glu Gly Lys Ile Phe Ser Phe Tyr Val Phe Ser Thr Thr Phe

130 135 140Thr Ser Ser Lys His Pro Asn Leu Gln Val Phe Ile Glu Asp Lys Asn145 150 155 160Tyr Tyr Thr Asn Ala Phe Ile Lys Pro Gln Lys Glu Asn Gln Glu Asn

165 170 175Met Ser Glu Asn Ala Pro Lys Asp Ala Gln Lys Asn Asn Lys Pro Leu

180 185 190Lys Glu Glu Lys Glu Glu Thr Lys Glu Lys Glu Glu Glu Thr Ile Ile

195 200 205Ile Gly Asp Asn Thr Asn Ala Met Lys Ile Ile Lys Lys Asp Ile Gln

210 215 220Lys Gly Tyr Lys Ala Leu Lys Ser Ser Gln Arg Lys Trp Tyr Cys Leu225 230 235 240Trp Ala Cys Ser Lys Lys Ser Lys Leu Ser Leu Met Pro Lys Glu Ile

245 250 255Phe Asn Asp Lys Gln Phe Thr Tyr Phe Lys Phe Asp Lys Arg Leu Ala

260 265 270Leu Ser Lys Phe Pro Val Ile Tyr Lys Val Val Asp GlyTyr Asp Asn

275 280 285Pro Val Asn Thr Arg Ile Val Gly Asp Tyr Ile Ile Ala Glu Asp Val

290 295 300Ser Thr Lys Trp Thr Leu Arg Leu Gly Lys Asp Tyr Leu Cys Ile Arg305 310 315 320Phe Val Lys Arg Arg Lys Gly Glu

325(2) SEQ ID NO 787 message

Sequence properties:

(A) length: 335 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...335

(xi) sequence representation: SEQ ID NO 787: Val Met Phe His Lys Ala Leu Ile Thr Phe Ile Val Leu Trp Phe Phe 151015 Leu Asn Gly Leu Gly Ala Tyr Asp Phe Lys His Cys Gln Ala Phe Phe

20 25 30Lys Lys Ala Ser Leu Gln Lys Gly Gly Val Ala Leu Lys Glu Leu Pro

35 40 45Lys Gly Val Tyr Leu Tyr Tyr Ser Lys Thr Tyr Pro Lys His Ala Lys

50 55 60Val Ile Lys Ser Asp Pro Phe Ile Gly Leu Tyr Leu Leu Gln Ser Ala65 70 75 80Pro Ser Glu Tyr Val Tyr Thr Leu Arg Asp Leu Asp Lys Asp Ala Leu

8590 95Ile Arg Pro Met Ala Ser Ile Gly Ala Asn Gln Ala Thr Glu Ala Arg

100 105 110Leu Leu Val Gly Gln Lys Gly Tyr Asp Arg Tyr Ala Gln Ile Ser Gln

115 120 125Lys Thr Gln Lys Asn Gly Val Ile Ser Asn Ile Cys Tyr Gln Met Leu

130 135 140Gly Leu Gly Val Gly Gly Asn Gly Phe Ile Glu Thr Lys Phe Ile Lys145 150 155 160Arg Phe Leu Asn Gln Gln Glu Pro Tyr Tyr Gly Asp Ile Gly Val Arg

165 170 175Leu Glu Glu Arg His Lys Arg Leu Val Val Ala Gln Phe Asp Pro Phe

180 185 190Phe Pro Lys Asn Pro Phe Leu Lys Asn Asp Glu Ile Leu Ala Ile Asn

195 200 205Asp Tyr Lys Ile His Ser Leu Ala Glu Phe Glu Trp Val Val Ser Asn

210 215 220Leu Ser Tyr Gln Ser Leu Ala Lys Val Lys Ile Lys Arg Asn His Gln225 230 235 240Ile Lys Glu Val Thr Leu Lys Val Asn Lys Arg Tyr Gly Gly Phe Leu

245 250 255Leu Lys Asp Thr Phe Leu Glu Arg Tyr Gly Ile Ala Leu Asp Glu Arg

260 265 270Phe Ile Ile Thr Lys Ile Gly Ala His Leu Pro Lys Gly Leu Asp Phe

275 280 285Leu Lys Leu Gly Asp Arg Ile Leu Trp Val Asn His Arg Ser Val Ser

290 295 300Phe Asn Pro Lys Ala Leu Arg Glu Ala Leu Ser Thr Pro Lys Ile Glu305 310 315320Leu Leu Val Trp Arg Gln Gly Phe Glu Phe Tyr Ile Lys Val Arg

325330335 (2) information SEQ ID NO 788

Sequence properties:

(A) length: 250 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...250

(xi) sequence representation: SEQ ID NO 788: Met Leu Gly Ser Val Lys Lys Thr Leu Phe Gly Val Leu Cys Leu Gly 151015 Ala Leu Cys Leu Arg Gly Leu Met Ala Glu Pro Asp Ala Lys Glu Leu

20 25 30Val Ser Leu Gly Ile Glu Ser Val Lys Lys Gln Asp Phe Ala Gln Ala

35 40 45Lys Ala His Phe Glu Lys Ala Cys Glu Leu Lys Glu Gly Phe Gly Cys

50 55 60Val Phe Leu Gly Ala Phe Tyr Glu Glu Gly Lys Gly Val Gly Lys Asp65 70 75 80Leu Lys Lys Ala Ile Gln Phe Tyr Thr Lys Gly Cys Glu Leu Asn Asp

85 90 95Gly Tyr Gly Cys Arg Leu Leu Gly Asn Leu Tyr Tyr Asn Gly Gln Gly

100 105 110Val Ser Lys Asp Ala Lys Lys Ala Ser Gln Tyr Tyr Ser Lys Ser Cys

115 120 125Glu Leu Asn His Ala Glu Gly Cys Thr Val Leu Gly Ser Leu His His

130 135 140Tyr Gly Val Gly Thr Pro Lys Asp Leu Arg Lys Ala Leu Asp Leu Tyr145 150 155 160Glu Lys Ala Cys Asp Leu Lys Asp Ser Pro Gly Cys Ile Asn Ala Gly

165 170 175Tyr Met Tyr Gly Val Ala Lys Asn Phe Lys Glu Ala Ile Val Arg Tyr

180 185 190Ser Lys Ala Cys Glu Leu Lys Asp Gly Arg Gly Cys Tyr Asn Leu Gly

195 200 205Val Met Gln Tyr Asn Ala Gln Gly Thr Ala Lys Asp Glu Lys Gln Ala

210 215 220Val Glu Asn Phe Lys Lys Gly Cys Lys Ser Ser Val Lys Glu Ala Cys225 230 235 240Asp Ala Leu Lys Glu Leu Lys Ile Glu Leu

245631 (2) SEQ ID NO 789 message

Sequence properties:

(A) length: 123 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...123

(xi) sequence representation: SEQ ID NO 789: Met Arg Leu Leu Ile Ala Leu Val Leu Phe Leu Trp Trp Leu Asn Leu 151015 Gly Ala Lys Glu Ala Asp Phe Ile Ser Asp Trp Glu Tyr Gly Leu Ala

20 25 30Leu Tyr Lys Asn Pro Arg Gly Val Ala Cys Ala Lys Cys His Gly Ile

35 40 45Lys Gly Glu Gln Gln Glu Ile Thr Phe Tyr Tyr Glu Lys Gly Glu Lys

50 55 60Lys Ile Leu Tyr Ala Pro Lys Ile Asn His Leu Asp Phe Lys Thr Phe65 70 75 80Lys Asp Ala Leu Ser Leu Gly Lys Gly Met Met Pro Lys Tyr Asn Leu

85 90 95Asn Leu Glu Glu Ile Gln Ala Ile Tyr Leu Tyr Ile Thr Ser Leu Gly

100 105 110His Lys Asp Glu Arg Lys Asp Pro Ser Lys Pro

115120 (2) SEQ ID NO 790 information

Sequence properties:

(A) length: 180 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...180

(xi) sequence representation: 790: Met Leu Asn Lys Phe Lys Lys Ile Val Gly Val Gly Val Leu Val Gly 151015 Cys Leu Gly Val Leu Gln Ala Lys Asn Ser Leu Phe Val Leu Pro Tyr SEQ ID NO

20 25 30Glu Gln Arg Asp Ala Leu Asn Ser Leu Ile Ser Gly Ile Ser Ser Ala

35 40 45Arg Glu Asn Val Lys Ile Ala Ile Tyr Ser Phe Thr His Arg Asp Ile

50 55 60Ala Arg Ala Ile Lys Ser Val Ala Ser Arg Gly Ile Lys Val Gln Ile65 70 75 80Ile Tyr Asp Tyr Glu Ser Asn His Asn Asn Lys Gln Ser Thr Ile Gly

85 90 95Tyr Leu Asp Lys Tyr Pro Asn Thr Lys Val Cys Leu Leu Lys Gly Leu

100 105 110Lys Ala Lys Asn Gly Asn Tyr Tyr Gly Ile Met His Gln Lys Val Ala

115 120 125Ile Ile Asp Asp Lys Ile Val Phe Leu Gly Ser Ala Asn Trp Ser Lys

130 135 140Asn Ala Phe Glu Asn Asn Tyr Glu Val Leu Leu Lys Thr Asp Asp Thr145 150 155 160Glu Thr Ile Leu Lys Ala Lys Ser Tyr Tyr Gln Lys Me5 Leu Glu Gly

165 170 175Cys Val Gly Phe

180(2) SEQ ID NO 791 message

Sequence properties:

(A) length: 140 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...140

(xi) sequence representation: SEQ ID NO 791: Met Arg Arg Ser Leu Ala Phe Cys Leu Leu Ala Leu Leu Gly Leu Gln 151015 Val Leu Gly Ala Arg Asp Phe Ser Gln Leu Lys Asn Glu Glu Leu Leu

20 25 30Lys Leu Ala Gly Thr Leu Pro Ser Asn Glu Ala Ile Asp Tyr Arg Met

35 40 45Glu Val Ser Lys Arg Leu Lys Ala Leu Ser Ala Glu Asp Ala Lys Lys

50 55 60Phe Arg Ala Asn Phe Ser Arg Ile Ala Arg Lys Asn Leu Ser Lys Met65 70 75 80Ser Glu Glu Asp Phe Lys Lys Met Arg Glu Glu Val Arg Lys Glu Leu

85 90 95Glu Glu Lys Thr Lys Gly Leu Ser Ala Glu Glu lle Lys Ala Lys Gly

100 105 110Leu Asn Val Ser Val Cys Ser Gly Asp Thr Arg Lys Val Trp Cys Arg

115120125 Ala Val Lys Lys Lys Asp Glu His Cys Ser Pro Lys 150135140 (2) SEQ ID NO 792 information

Sequence properties:

(A) length: 152 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...152

(xi) sequence representation: SEQ ID NO 792: Met Lys Lys Ala Leu Lys Ile Leu SerVal Gly Ala Leu Leu Phe Val 151015 Ala Leu Asn Ala Lys Asp Phe Ser Lys Thr Ser Asp Glu Asp Leu AIa

20 25 30Lys Met Ala Gly Val Val Ala Pro Gln Asp Ile Val Asp Tyr Thr Lys

35 40 45Glu Leu Lys Lys Arg Met Glu Lys Met Pro Glu Asp Lys Arg Lys Ala

50 55 60Phe His Lys Gln Leu His Glu Tyr Ala Thr Lys Asn Thr Asp Lys Met65 70 75 80Thr Val Ala Asp Phe Glu Ala Arg Gln Lys Ala Ile Lys Glu Ala Leu

85 90 95Lys Lys Gly Asn Met Glu Asp Met Asp Asp Asp Phe Gly Leu Arg Ser

100 105 110Cys Lys His Gly Lys Lys His Lys His Asp Lys His Gly Lys Lys His

115 120 125Gly Lys Lys His Asp Lys Asp His Asp Asp Lys Asp His Asp His His

130135140 Asp Glu Asp His Ser Asp Lys His 145150 (2) SEQ ID NO:793 information

Sequence properties:

(A) length: 140 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...140

(xi) sequence representation: SEQ ID NO 793:Met Leu Lys Lys Leu Leu Leu Ile Ser Leu Phe Leu Gly Phe Leu Arg 151015 Ala Glu Gly Glu His Tyr Glu Ile Ile Ala Glu Leu Ser Lys Ala Phe

20 25 30Leu Lys Ala Lys Glu Val Leu Thr Ala Ile Asn Lys Thr Cys Ile Glu

35 40 45Thr Gly His Asp Arg Thr Gln Ile Arg Leu Gln Asn Asp Phe Leu Glu

50 55 60Asn Leu Ser Gln Thr Glu Gln Gln Phe Asp Asp Tyr Phe Glu Lys Asp65 70 75 80Phe Lys Ser Val Gly Val Leu Lys Thr Leu Leu Lys Asp Ile Gln Ser

85 90 95Leu Glu Lys Thr Ser Asn Lys Leu Val Cys Val Ala Pro Lys Asn Ala

100 105 110Lys Asn Phe Glu Ile Leu Glu Gly Ala Ile Thr Gln Ile Ile Gly Leu

115 120 125Glu Glu Gln Met Asn Gln Phe Ile Asn Gly Ala Lys

130135140 (2) information of SEQ ID NO:794

Sequence properties:

(A) length: 66 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...66

(xi) sequence representation: SEQ ID NO 794: Leu SerGly Glu Leu Arg Leu Ser Trp Trp Leu Val Ala Arg Cys Lys 151015 Thr Leu Phe Val Leu Phe Cys Glu Gly Ser Ala Phe Ser Ser Leu Leu

20 25 30Ile Ser Ser Ile Leu Phe Ser Leu Leu Ile Arg Ser Phe Thr Ser Leu

35 40 45Val Thr Phe Ser Ser Ser Ser Ser Cys Ser Ile Phe Phe Ile Ser Leu

505560 Leu Gly65(2) SEQ ID NO:795 information

Sequence properties:

(A) length: 89 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...89

(xi) sequence representation: SEQ ID NO 795: Leu Val Val Ser Gly Ser Leu Gln Asn Ile Val Arg Ser Phe Leu Arg 151015 Arg Ile Ser Val Phe Phe Ile Ile Asp Phe Ile Asn Phe Ile Phe Val

20 25 30Ile Asp Gln Ile Ile His Phe Phe Gly Asp Phe Phe Ile Phe Phe Phe

35 40 45Met Leu Asn Leu Phe Tyr Ile Leu Ile Arg Leu Ile Asp Leu Ile Val

50 55 60Leu Ser Gly Phe Ser Val Val Leu Val Arg Leu Gly Xaa Phe Phe Arg65 70 75 80Leu Ile Phe Ala Cys Ala Gln His Ala

85(2) informationof SEQ ID NO 796

Sequence properties:

(A) length: 118 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...118

(xi) sequence representation: SEQ ID NO 796 Meu Lys Lys Ser Leu Cys Leu Ser Phe Phe Leu Thr Phe Ser Asn Pro 151015 Leu Gln Ala Leu Val Ile Glu Leu Leu Glu Glu Ile Lys Thr Ser Pro

20 25 30His Lys Gly Thr Phe Lys Ala Lys Val Leu Asp Ser Lys Glu Pro Arg

35 40 45Gln Val Leu Gly Val Tyr Asn Ile Ser Pro His Lys Lys Leu Thr Leu

50 55 60Thr Ile Thr His Ile Ser Thr Ala Ile Val Tyr Gln Pro Leu Asp Glu65 70 75 80Lys Leu Ser Leu Glu Thr Thr Leu Ser Pro Asn Arg Pro Thr Ile Pro

85 90 95Arg Asn Thr Gln Ile Val Phe Ser Ser Lys Glu Leu Lys Glu Pro His

100 105 110Ser Asn Pro Ile Pro Ser

115(2) SEQ ID NO 797 message

Sequence properties:

(A) length: 245 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...245

(xi) sequence representation: SEQ ID NO 797: Leu Lys Ala Phe Gln Thr Phe Gly Val Phe Gly Thr Ser Val Ile Thr 151015 Cys Ile Thr Ala Gln Asn Thr Gln Gly Val His Gly Val Tyr Pro Leu

20 25 30Ser Val Glu Ser Val Lys Ala Gln Ile Leu Ala Ile Arg Asp Asp Phe

35 40 45Ser Ile Lys Ala Phe Lys Met Gly Ala Leu Cys Asn Ala Gln Ile Ile

50 55 60Glu Cys Val Ala ASn Ala Leu Glu Thr Cys Asp Phe Gly Leu Cys Val65 70 75 80Leu Asp Pro Val Met Val Ala Lys Asn Gly Ala Leu Leu Leu Glu Glu

85 90 95Glu Ala Ile Leu Ser Leu Lys Lys Arg Leu Leu Pro Lys Thr Asn Leu

100 105 110Leu Thr Pro Asn Leu Pro Glu Val Tyr Ala Leu Thr Gly Val Gln Ala

115 120 125Arg Asp Asp Lys Ser Ala Ser Lys Ala Met Gly Val Leu Arg Asp Leu

130 135 140Gly Val Lys Asn Ala Val Ile Lys Gly Gly His Thr Glu His Phe Gln145 150 155 160Gly Glu Phe Ser Asn Asp Trp Val Phe Leu Glu Asp Ala Glu Phe Thr

165 170 175Leu Ser Ala Lys Arg Phe ASn Thr Lys Asn Thr His Gly Thr Gly Cys

180 185 190Thr Leu Ser Ser Leu Ile Val Gly Leu Leu Ala Gln Gly Leu Asp Leu

195 200 205Lys Asn Ala Ile Thr Lys Ala Lys Glu Leu Leu Thr Ile Ile Ile Gln

210 215 220Asn Pro Leu Asn Ile Gly His Gly His Gly Pro Leu Asn Leu Trp Ser225 230 235 240Ile Lys Lys His Val

245(2) information of SEQ ID NO 798

Sequence properties:

(A) length: 213 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...213

(xi) sequence representation: SEQ ID NO 798 Val Leu Glu Lys Gln Asp Lys Asp Leu Phe Leu Leu Gln Val Gly Asn 151015 Arg Ile Ile Pro Thr Lys Ser Glu Gln Glu Leu Lys Ile Asn Gln Pro

20 25 30Tyr Phe Ala Thr Met Gln Arg Asn Gln Leu Gly Asp Ile Val Leu Lys

35 40 45Asn Leu Val Pro Ala Pro Lys Ile Leu Asp Ala Leu Asp Asp Leu Pro

50 5560Val Ile Glu Met Lys Lys Leu Lys Glu Ile Leu Ser Ala Lys Asp Asn65 70 75 80Thr Pro Leu Lys Glu Tyr Lys Glu Leu Leu Ser Glu Lys Leu Ile His

85 90 95Ala Lys Ser Ser Gln Glu Phe Leu Asn Thr Ala Asn Met Leu Leu Ser

100 105 110Leu Gln Ser Gln Val Leu Ser Phe Val Val Glu Asn Glu Arg Lys Lys

115 120 125Ala Phe Leu Gln Met Lys Ala Lys Lys Gln Ser Val Asp Phe Tyr Ala

130 135 140Leu Tyr Pro Asn Leu Gly Glu Ile Gly Gly Val Ile Tyr Leu Lys Glu145 150 155 160Lys Glu Lys Gln Leu Phe Leu Lys Thr Thr Leu Gln Arg Thr Lys Glu

165 170 175Val Leu Lys Glu Ala Gln Asn Thr Leu Leu Gly Phe Ser Phe Val Glu

180 185 190Iie Val Cys Glu Lys Thr Pro Met Leu Phe Ala Phe Glu Asp Arg Leu

195 200 205Leu Asp Thr Leu Gly

210(2) SEQ ID NO 799 message

Sequence properties:

(A) length: 91 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...91

(xi) sequence representation: SEQ ID NO 799: Met Ser Asp Glu Ile Thr Gln Glu Asn Glu Leu Glu Ile Asn Ser Asn 151015 Asn Gln Asn Gln Glu Pro Lys Glu Val Glu Lys Met Pro Leu Asn Asn

20 25 30Ile Gln Lys Ala Lys Lys Leu Lys Asn His Ala Asn Leu Ile Val Arg

35 40 45Arg Thr Asp Glu Leu Asp Lys Val Ile Asn Lys Arg Glu Ser Leu Gln

50 55 60Arg Glu Phe Lys Arg Arg Ile Lys His Leu Asp Asn Lys Ile Glu Thr65 70 75 80Leu Ser Asn Asn Ile Glu Glu Leu Lys Arg Lys

8590 (2) SEQ ID NO 800 information

Sequence properties:

(A) length: 172 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...172

(xi) sequence representation: 800: Met Lys Lys Tyr Gln Asn Lys Arg Lys Leu Gly Lys Arg Ile Asn Cys 151015 Phe Ile Ser Asn Glu Cys Lys Asp Ile Leu Glu Asn Tyr Leu Lys Val SEQ ID NO

20 25 30Lys Lys Ile Ser Val Thr Glu Cys Ile Glu Ser Leu Leu Leu Ala Leu

35 40 45Asp Pro Ser Lys Glu Thr Leu Arg Ala Arg Asp Phe Tyr Glu Ser Leu

50 55 60Phe Lys Val Ile Ser Leu Asn Gln His Val Tyr Lys Glu LeuMet Ala65 70 75 80Asn Gly Asn Asn Ile Asn Gln Ile Ala Lys Asn Thr Asn Ile Ala Ile

85 90 95Lys Tyr Asn Lys Pro Phe Tyr Leu Gln Asn Leu Ala Phe Leu Glu Glu

100 105 110Ile Phe Lys Val Met Asp Thr Leu Asn Lys Asn Val Glu Glu Cys Lys

115 120 125Lys Ile Ser Leu Glu Leu Leu Leu Gln Ile Tyr Lys Glu Gln Lys Ser

130 135 140Gln Thr Glu Phe Asn Ala Ile Ser Lys Ile Leu Asn Ala Leu Asn Glu145 150 155 160Lys Gln Ser Thr Thr Glu Pro Lys Lys Asp Asn Ala

165170 (2) SEQ ID NO 801 information

Sequence properties:

(A) length: 320 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...320

(xi) sequence representation: 801: Met Asn Thr Asn Leu Lys Lys Ala Leu Phe Leu Thr Thr Leu Gly Tyr 151015 Leu Gln Ala Asn Glu GlyPhe Leu Ala Ile Met Pro Asp Glu Asn Lys SEQ ID NO

20 25 30Gln Glu Asp Ile Ser Gln Glu Gln Lys Leu Glu His Lys Met Glu Gln

35 40 45Lys Ile Ala Pro Gln Asn Thr Leu Lys Lys Gln Gln Ser Ala Pro Leu

50 55 60Gln Ser Ala Glu Leu Leu Gln Ser Gln Val Lys Arg Glu Val Lys Glu65 70 75 80Gln Lys Lys Ser Gln Lys His Leu Val Ala Met Gln Thr Lys Asn Gly

85 90 95Phe Phe Leu Gly Ser Glu Ile Ala Ile Thr Gly Thr Ser Leu Lys Gln

100 105 110Ser Leu Ser Leu Ile Ser Asn Ala Thr Asp Asp Leu Leu Thr Tyr Ser

115 120 125Lys Thr Ser Lys Asn Ala Asn Phe Asn Met Gly Leu Leu Ile Gly Tyr

130 135 140Gln His Tyr Phe Gly Ala Ser Lys Arg His Gly Ile Lys Ile Ser Ser145 150 155 160His Leu Tyr Gly Gly Thr Pro Ser Asp Val Ser Thr Asp Ile Lys Ile

165 170 175Tyr Lys Ser Lys Val Ser Thr Asn Tyr Thr Pro Leu Asn Phe Gly Ile

180 185 190Asp Val Lys Tyr Leu Phe Asp Phe Leu Asn Val Ile Lys Lys Asn Arg

195 200 205His Thr Leu Gly Leu Ser Val Gly Phe Gly Trp Arg Met Gln Tyr Tyr

210 215 220Phe Ala Lys Ile Asp Pro Ile Lys Thr Ser His Ser Glu Phe Ile Thr225 230 235 240Asn Lys Pro Lys AspIle Phe Asn His Gly Phe Tyr Pro Thr Ile Gly

245 250 255Leu His Tyr Tyr Leu Asn His His Gln Phe Glu Val Asn Tyr Arg Phe

260 265 270Gly Gly Ala Ile Asn Tyr Gln Ser Val Val Pro Ser Lys Ile Val Val

275 280 285Gln Asn Gly Asn Phe Lys Gly Glu Val Leu Phe Ser Asn Phe Leu Thr

290295300 Lys Ala Thr Asn Ser Ser Tyr Ile Ala Phe Asn Tyr Ala Tyr Leu Phe 305310315320 (2) SEQ ID NO:802 information

Sequence properties:

(A) length: 486 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...486

(xi) sequence representation: 802: Leu Ala Ile Lys Arg Glu Lys Met Lys Asn Ser Ala Pro Leu Lys Asn 151015 Lys Val Phe Cys Gly Leu Tyr Val Leu Ser Leu Ser Ala Ser Val Gln SEQ ID NO

20 25 30Ala Phe Asp Tyr Lys Ile Glu Val Leu Ala Glu Ser Phe Ser Lys Val

35 40 45Gly Phe Asn Lys Lys Lys Ile Asp Ile Ala Arg Gly Ile Tyr Pro Thr

50 55 60Glu Thr Phe Val Thr Ala Val Gly Gln Gly Asn Ile Tyr Ala Asp Phe6570 75 80Leu Ser Lys Ser Leu Lys Asp Gln Gly His Val Leu Glu Gly Lys Val

85 90 95Gly Gly Thr Ile Gly Gly Ile Ala Tyr Asp Ser Thr Lys Phe Asn Gln

100 105 110Gly Gly Ser Val Ile Tyr Asn Tyr Ile Gly Tyr Trp Asp Gly Tyr Leu

115 120 125Gly Gly Lys Arg Ala Leu Leu Asp Gly Thr Ser Ile His Glu Cys Ala

130 135 140Leu Gly Ser Asp Gly Lys Val Ile Asp Ser Ile Ala Cys Gly Asn Ala145 150 155 160Arg Ala Asn Lys Ile Arg Arg Asn Tyr Leu Met Asn Asn Ala Pne Leu

165 170 175Glu Tyr Arg Tyr Lys Asp Ile Phe Ala Ala Lys Gly Gly Arg Tyr Gln

180 185 190Ser Asn Ala Pro Tyr Met Ser Ser Tyr Thr Gln Gly Phe Glu Ile Ser

195 200 205Ala Lys Ile Lys Asp Lys Asn Glu Gly Ser His Lys Leu Trp Trp Phe

210 215 220Ser Ser Trp Gly Arg Ala Phe Ala Tyr Gly Glu Trp Ile Tyr Asp Phe225 230 235 240Tyr Ser Pro Arg Thr Val Ile Lys Asn Gly Arg Thr Leu Asn Tyr Gly

245 250 255Ile His Leu Val Asp Tyr Thr Tyr Glu Arg Lys Gly Val Ser Val Ser

260 265 270Pro Phe Phe Gln Phe Ser Pro Gly Thr Tyr Tyr Ser Pro Gly Val Ala

275 280 285Val Gly Tyr Asp Ser Asn Pro Asn Phe Asn Gly Val Gly Phe Arg Ser

290 295 300Glu Thr Lys Ala Tyr Ile Leu Leu Pro Val His Ala Pro Leu Lys Arg305 310 315 320Asp Thr Tyr Arg Tyr Ala Val Lys Ala Gly Thr Ala Gly Gln Ser Leu

325 330 335Leu Ile Arg Gln Arg Phe Asp Tyr Asn Glu Phe Asn Phe Gly Gly Ala

340 345 350Phe Tyr Lys Val Trp Lys Asn Ala Asn Ala Tyr Ile Gly Thr Thr Gly

355 360 365Asn Pro Leu Gly Ile Asp Phe Trp Thr Asn Ser Val Tyr Asp Ile Gly

370 375 380Gln Ala Leu Ser His Val Val Thr Ala Asp Ala Val Ser Gly Trp Val385 390 395 400Phe Gly Gly Gly Val His Lys Lys Trp Leu Trp Gly Thr Leu Trp Arg

405 410 415Trp Thr Ser Gly Ala Leu Ala Asn Glu Ala Ser Ala Ala Val Asn Val

420 425 430Gly Tyr Lys Ile Ser Lys Ser Leu Thr Ala Ser Val Lys Leu Glu Tyr

435 440 445Leu Gly Val Met Thr His Ser Gly Phe Thr Val Gly Ser Tyr Arg Pro

450 455 460Thr Pro Gly Ser Lys Ala Leu Tyr Ser Asp Arg Ser His Leu Met Thr465 470 475 480Thr Leu Ser Ala Lys Phe

485(2) SEQ ID NO 803 information

Sequence properties:

(A) length: 167 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...167

(xi) sequence representation: SEQ ID NO 803: Val Cys Ile Ile Phe Asp Ala Asp Ile Lys Lys Glu Asn Gln Glu Ser 151015 Asp Ala Gly Phe Asp Asn Lys Leu Lys His Ile Arg Glu Lys Phe Lys

20 25 30Glu Lys Gly Thr Asp Phe Pro Lys Glu Gln Ile Phe Leu Phe Pro Asn

35 40 45Asn Gln Asp Asp Gly Asp Leu Glu Thr Leu Leu Leu Glu Ile Ala Lys

50 55 60His Asp Glu Phe Leu Lys Cys Phe Glu Gly Tyr Leu Glu Cys Ile Lys65 70 75 80Ser Lys Glu His Tyr Lys Pro Ile Lys Asn Ile Arg Lys Asn Met Leu

85 90 95Tyr Ala Tyr Leu Glu Ala Leu Gly Leu Glu Asn Leu Thr Lys Thr Asn

100 105 110Ile Asp Val Phe Asp Ser Lys Gly Lys Ile Lys Ser Arg Tyr Glu Glu

115 120 125Asn Tyr Lys Lys Leu Thr Glu Glu Val Ile Asp Phe Ser Ser Asn Ser

130 135 140Leu Ile Pro Leu Lys Asn Phe Leu Gly Gln Phe Ala Glu Asn Lys Gln145 150 155 160Lys Thr Asn Pro Lys Ile Phe

165(2) SEQ ID NO 804 information

Sequence properties:

(A) length: 210 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...210

(xi) sequence representation: 804: Met Val Leu Lys Thr Lys Leu Lys Ile Ile Ser Ser Val Ile Leu Ser 151015 Thr Leu Leu Trp Val Gly Cys Ser Ser Glu Met Ala Thr Tyr Gln Asn SEQ ID NO

20 25 30Val Asn Asp Ala Thr Lys ASn Thr Thr Ala Ser Ile Asn Ser Thr Asp

35 40 45Leu Leu Leu Thr Ala Ash Ala Met Leu Asp Ser Met Phe Ser Asp Pro

50 55 60Asn Phe Glu Gln Leu Lys Gly Lys His Leu Ile glu Val Ser Asp Val65 70 75 80Ile Asn Asp Thr Thr Gln Pro Asn Leu Asp Met Asn Leu Leu Thr Thr

85 90 95Glu Ile Ala Arg Gln Leu Arg Leu Arg Ser Asn Gly Arg Phe Asn Ile

100 105 110Thr Arg Ala Ser Gly Gly Ser Gly Ile Glu Ala Asp Ser Arg Met Val

115 120 125Lys Gln Arg Glu Lys Glu Arg Glu Ser Glu Glu Tyr Asn Gln Asp Thr

130 135 140Thr Val Glu Lys Gly Thr Leu Lys Ala Ala Asp Leu Ser Leu Ser Gly145150 155 160Lys Val Ser Ser Ile Ala Ala Ser Ile Ser Ser Ser Arg Gln Arg Leu

165 170 175Asp Tyr Asp Phe Thr Leu Ser Leu Thr Asn Arg Lys Thr Gly Glu Glu

180 185 190Val Trp Ser Asp Val Lys Pro Ile Val Lys Asn Ala Ser Asn Lys Arg

195200205 Met Phe210(2) SEQ ID NO 805 information

Sequence properties:

(A) length: 184 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...184

(xi) sequence representation: 805 SEQ ID NO Met Lys Ala Phe Leu Lys Ile Cys Met Val Leu Ile Phe Val Gly Val 151015 Ala His Ala Lys Asn Pro Leu Thr Leu Ser Lys Glu Glu Glu Val Leu

20 25 30Gln Asn Leu Gln Ser Phe Ser Ala His Phe Lys Gln Val Leu Lys Asn

35 40 45Glu Lys Pro Leu Val Tyr Tyr Gly Val Leu Lys Ala Lys Ala Pro Asn

50 55 60Trp Ala Leu Trp Val Tyr Glu Lys Pro Leu Lys Lys Glu Ile Tyr Met65 70 75 80Asn Asp Lys Glu Val Val Val Tyr Glu Pro Asn Leu Phe Gln Ala Thr

85 90 95Ile Thr Pro Leu Lys Asp Lys Thr Asp Phe Phe Thr lle Leu Lys Gln

100 105 110Leu Lys Lys Gln Thr Asp Gly Ser Phe Lys Thr Thr Ile Asn Lys Thr

115 120 125Thr Tyr Arg Leu Val Phe Lys Asp Gly Lys Pro Phe Ser Leu Glu Phe

130 135 140Lys Asp Asp Met Asn Asn Leu Val Thr Ile Thr Phe Ser Gln Ala Glu145 150 155 160Ile Asn Pro Lys Ile Pro Asn Glu Ile Phe Val Phe Asn Pro Lys Asp

165 170 175Glu Asn Ile Asp Ile Val Arg Gln

180(2) SEQ ID NO 806 information

Sequence properties:

(A) length: 185 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...185

(xi) sequence representation: 806 SEQ ID NO Met Arg Ile Lys Ala Tyr Phe Leu Arg Phe Ile Ala Leu Val Phe Ile 151015 Val Leu Leu Gly Phe ser Ala Cys Lys Asn Ser Gln Lys Ser Gln Asp

20 25 30Ser Gln Asn Asn Thr Thr Gln Gln Asp Ser Pro Lys Thr Tyr Thr Ala

35 40 45Met Asp Leu Asn Asn Gln Glu Tyr Thr Ile Met Gly Asp Leu Asp Ser

50 55 60Leu Asn Ile Ser Pro Asp Pro Asn Thr Pro Thr Leu Leu Ile Leu Ser65 70 75 80Ala Leu Asp Asn Ser Leu Lys Asp Tyr Ala Pro Thr Phe Asn Val Leu

85 90 95Lys Lys Thr Phe Lys Asp Arg Leu Arg Val Leu Ile Leu Leu Asn Gln

100 105 110Pro Tyr Ser Ser Asp Ala Ile Lys Gly Phe Ile Ala Pro Ser Gln Thr

115 120 125Asp Leu Met Ile Leu Asn Pro Lys Asp Thr Ala Leu Phe Asp His Leu

130 135 140Asn His Asp Ala Leu Asn His Ser Phe Asn Met Leu Leu Tyr Asp Lys145 150 155 160His Gln Leu Ile Lys Met Tyr Gln Gly Ile Val Pro Ala Glu Met Leu

165 170 175Gln Phe Asp Ile Ser Asn Leu Lys Asp

180185 (2) SEQ ID NO 807 information

Sequence properties:

(A) length: 363 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...363

(xi) sequence representation: 807 SEQ ID NO: Met Val Ser Thr Leu Lys Pro Leu Lys Ile Gly Lys His Thr Ile Lys 151015 Phe Pro Ile Phe Gln Gly Gly Met Gly Val Gly Ile Ser Trp Asp Glu

20 25 30Leu Ala Gly Asn Val Ala Lys Glu Gly Ala Leu Gly Val Ile Ser Ala

35 40 45Val Gly Thr Gly Tyr Tyr Lys Asn Met Arg Phe Val Glu Arg Ile Val

50 55 60Ala Lys Lys Pro Phe Glu Ala Leu Asn Phe Tyr Ser Lys Lys Ala Leu65 70 75 80Asn Glu Ile Phe Ala Asn Ala Arg Lys Ile Cys Gly Asn Lys Pro Leu

85 90 95Gly Ala Asn Ile Leu Tyr Ala Ile Asn Asp Tyr Gly Arg Val Leu Arg

100 105 110Asp Ser Cys Glu Ala Gly Ala Asn Ile Ile Ile Thr Gly Ala Gly Leu

115 120 125Pro Thr Ash Met Pro Glu Phe Ala Lys Asp Phe Ser Asp Val Ala Leu

130 135 140Ile Pro Ile Ile Ser Ser Ala Lys Ala Leu Lys Ile Leu Cys Lys Arg145 150 155 160Trp Ser Asp Arg Tyr Lys Arg Ile Pro Asp Ala Phe Ile Val Glu Gly

165 170 175Pro Leu Ser Gly Gly His Gln Gly Phe Lys Tyr Glu Asp Cys Phe Lys

180 185 190Glu Glu Phe Gln Leu Glu Asn Leu Val Pro Lys Val Val Glu Ala Ser

195 200 205Lys Glu Trp Gly Asn Ile Pro Ile Iie Ala Ala Gly Gly Ile Trp Asp

210 215 220Lys Lys Asp Ile Asp Thr Met Leu Ser Leu Gly Ala Ser Gly Val Gln225 230 235 240Met Ala Thr Arg Phe Leu Gly Thr Lys Glu Cys Asp Ala Lys Ala Tyr

245 250 255Ala Asp Leu Leu Pro Thr Leu Lys Lys Glu Asp Ile Leu Leu Ile Lys

260 265 270Ser Pro Val Gly Tyr Pro Ala Arg Ala Ile Asn Thr Gly Val Ile Lys

275 280 285Arg Ile Glu Glu Gly Asn Ala Pro Lys Ile Ala Cys Val Ser Asn Cys

290 295 300Val Ala Pro Cys Asn Arg Gly Glu Glu Ala Lys Lys Val Gly Tyr Cys305 310 315 320Ile Ala Asp Gly Leu Gly Arg Ser Tyr Leu Gly Asn Arg Glu Glu Gly

325 330 335Leu Tyr Phe Thr Gly Ala Asn Gly Tyr Arg Val Asp Lys Ile Ile Ser

340 345 350Val His Glu Leu Ile Lys Glu Leu Thr Glu Gly

355360 (2) SEQ ID NO:808 information

Sequence properties:

(A) length: 363 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...363

(xi) sequence representation: 808: Met Val Ser Thr Leu Lys Pro Leu Lys Ile Gly Lys His Thr Ile Lys 151015 Phe Pro Ile Phe Gln Gly Gly Met Gly Val Gly Ile Ser Trp Asp Glu SEQ ID NO

20 25 30Leu Ala Gly Asn Val Ala Lys Glu Gly Ala Leu Gly Val Ile Ser Ala

35 40 45Val Gly TAr Gly Tyr Tyr Lys Asn Met Arg Phe Val Glu Arg Ile Val

50 55 60Ala Lys Lys Pro Phe Glu Ala Leu Ash Phe Tyr Ser Lys Lys Ala Leu65 70 75 80Asn Glu Ile Phe Ala Asn Ala Arg Lys Ile Cys Gly Asn Lys Pro Leu

85 90 95Gly Ala Asn Ile Leu Tyr Ala Ile Asn Asp Tyr Gly Arg Val Leu Arg

100 105 110Asp Ser Cys Glu Alu Gly Ala Asn Ile Ile Ile Thr Gly Ala Gly Leu

115 120 125Pro Thr Asn Met Pro Glu Phe Ala Lys Asp Phe Ser Asp Val Ala Leu

130 135 140Ile Pro Ile Ile Ser Ser Ala Lys Ala Leu Lys Ile Leu Cys Lys Arg145 150 155 160Trp Ser Asp Arg Tyr Lys Arg Ile Pro Asp Ala Phe Ile Val Glu Gly

165 170 175Pro Leu Ser Gly Gly His Gln Gly Phe Lys Tyr Glu Asp Cys Phe Lys

180 185 190Glu Glu Phe Gln Leu Glu Asn Leu Val Pro Lys Val Val Glu Ala Ser

195 200 205Lys Glu Trp Gly Asn Ile Pro Ile Ile Ala Ala Gly Gly Ile Trp Asp

210 215 220Lys Lys Asp Ile Asp Thr Met Leu Ser Leu Gly AlaSer Gly Val Gln225 230 235 240Met Ala Thr Arg Phe Leu Gly Thr Lys Glu Cys Asp Ala Lys Ala Tyr

245 250 255Ala Asp Leu Leu Pro Thr Leu Lys Lys Glu Asp Ile Leu Leu Ile Lys

260 265 270Ser Pro Val Gly Tyr Pro Ala Arg Ala Ile Asn Thr Gly Val Ile Lys

275 280 285Arg Ile Glu Glu Gly Asn Ala Pro Lys Ile Ala Cys Val Ser Asn Cys

290 295 300Val Ala Pro Cys Asn Arg Gly Glu Glu Ala Lys Lys Val Gly Tyr Cys305 310 315 320Ile Ala Asp Gly Leu Gly Arg Ser Tyr Leu Gly Asn Arg Glu Glu Gly

325 330 335Leu Tyr Phe Thr Gly Ala Asn Gly Tyr Arg Val Asp Lys Ile Ile Ser

340 345 350Val His Glu Leu Ile Lys Glu Leu Thr Glu Gly

355360 (2) SEQ ID NO 809 information

Sequence properties:

(A) length: 192 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...192

(xi) sequence representation: 809 SEQ ID NO:809 Leu Leu Gly Arg Asn Gly Val Thr Leu Asn Ile Arg Gln Val Phe Trp 151015 Trp Asp Asn Phe Asn Trp Ser Ile Gly Phe Tyr Asn Thr Phe Gly Asn

20 25 30Ser Asp Ala Phe Leu Gly Ser His Thr Met Pro Arg Gly Asn Asn Thr

35 40 45Ser Tyr Ile Ser Asn Glu Ile Ser Val Thr Thr Arg His Ala Gly Met

50 55 60Ile Gly Tyr Asp Phe Trp Asp Asn Thr Ala Tyr Asp Gly Leu Ala Asp65 70 75 80Ala Ile Thr Asn Ala Ash Thr Phe Thr Phe Tyr Thr Ser Val Gly Gly

85 90 95Ile His Lys Arg Phe Ala Trp His Val Phe Gly Ar9 Val Ser His Ala

100 105 110Asn Lys Asn Ala Leu Gly Gln Val Gly Arg Ala Asn Glu Tyr Ser Leu

115 120 125Gln Phe Asn Ala Ser Tyr Ala Phe Thr Glu Ser Val Leu Leu Asn Phe

130 135 140Arg Ile Tnr Tyr Tyr Gly Ala Arg Ile Asn Lys Gly Tyr Gln Ala Gly145 150 155 160Tyr Phe Gly Ala Pro Lys Phe Ash Ash Pro Asp Gly Asp Phe Ser Ala

165 170 175Asn Tyr Gln Asp Arg Ser Tyr Met Met Thr Asn Leu Thr Leu Lys Phe

180185190 (2) SEQ ID NO 810 information

Sequence properties:

(A) length: 354 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii)assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...354

(xi) sequence representation: 810: Met Gln Gln Gln Leu Thr Tyr Leu Asn Ala Gly Asn Val Phe Phe Asn 151015 Ala Met Asn Lys Ala Leu Glu Lys Asn Gly Thr Ala Thr Ala Asn Ser SEQ ID NO

20 25 30Thr Ser Ser Thr Ser Gly Ala Thr Gly Ser Asp Gly Gln Thr Tyr Ser

35 40 45Gln Gln Ala Ile Gln Tyr Leu Gln Gly Gln Gln Asn Ile Leu Ash Asn

50 55 60Ala Ala Asn Leu Leu Lys Gln Asp Glu Leu Leu Leu Glu Ala Phe Asn65 70 75 80Ser Ala Val Ala Ala Asn Ile Gly Asn Lys Glu Phe Asn Ser Ala Ala

85 90 95Phe Thr Gly Leu Val Gln Gly Ile Ile Asp Gln Ser Gln Leu Val Tyr

100 105 110Asn Glu Leu Thr Lys Asn Thr Ile Ser Gly Ser Ala Val Asn Asn Ala

115 120 125Gly Ile Asn Ser Asn Gln Ala Asn Ala Val Gln Gly Arg Ala Ser Gln

130 135 140Leu Pro Asn Ala Leu Tyr Asn Val Gln Val Thr Leu Asp Lys Ile Asn145 150 155 160Ala Leu Asn Asn Gln Val Arg Ser Met Pro Tyr Leu Pro Gln Phe Arg

165 170 175Ala Gly Asn Ser Arg Ala Thr Asn Ile Leu Asn Gly Phe Tyr Thr Lys

180185 190Val Gly Tyr Lys Gln Phe Phe Gly Lys Lys Arg Asn Ile Gly Leu Arg

195 200 205Tyr Tyr Gly Phe Phe Ser Tyr Asn Gly Ala Ser Val Gly Phe Arg Ser

210 215 220Thr Gln Asn Asn Val Gly Leu Tyr Thr Tyr Gly Val Gly Thr Asp Val225 230 235 240Leu Tyr Asn Ile Phe Ser Arg Ser Tyr Gln Asn Arg Ser Val Asp Met

245 250 255Gly Phe Phe Ser Gly Ile Gln Leu Ala Gly Glu Thr Phe Gln Ser Thr

260 265 270Leu Arg Asp Asp Pro Asn Val Lys Leu His Gly Lys Ile Asn Asn Thr

275 280 285His Phe Gln Phe Leu Phe Asp Phe Gly Met Arg Met Asn Phe Gly Lys

290 295 300Leu Asp Gly Lys Ser Asn Arg His Asn Gln His Thr Val Glu Phe Gly305 310 315 320Val Val Val Pro Thr Ile Tyr Asn Thr Tyr Tyr Lys Ser Ala Gly Thr

325 330 335Thr Val Lys Tyr Phe Arg Pro Tyr Ser Val Tyr Trp Ser Tyr Gly Tyr

340345350 Ser Phe (2) SEQ ID NO 81l information

Sequence properties:

(A) length: 748 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...748

(xi) sequence representation: SEQ ID NO 811: Met Glu Asp Phe Leu Tyr Asn Thr Leu Tyr Phe Ile Glu Asp Tyr Lys 151015 Leu Val Val Ile Phe Ser Phe Ile Gly Leu Ile Ala Leu Phe Phe Leu

20 25 30Tyr Lys Phe Ile Lys Thr Gln Lys Lys Val Phe Lys Asp Lys Ala Asn

35 40 45Gln Pro Gln Lys Lys Lys Ser Phe Lys Glu Ile Ile Ile Asp Gly Leu

50 55 60Lys Glu Arg Val Lys Thr Phe Gly Phe Trp Leu Gln Ala Ile Leu Leu65 70 75 80Leu Ser Tyr Ser Phe Ile Thr Ser Gly Leu Phe Phe Leu Ile Leu Leu

85 90 95Gly Asn Phe Tyr Asp Asp Asn Arg Leu Pro Glu Ser Asp Asp Asp Leu

l00 105 110Phe Asp Ile Trp Val Tyr Ala Ile Gln Asp Phe Pro Ala Tyr Tyr Phe

115 120 125Lys Ala Leu Thr Phe Ser Ser Leu Lys Ile Tyr Gly Phe Asn Ile Ser

130 135 140Leu Val Val Tyr Ser Ser Ile Leu Cys Ser Tyr Ile Phe Ile Thr Phe145 150 155 160Phe Val Trp Phe Leu Lys Tyr Leu Thr Arg Thr Arg Asp Ile Gly Ala

165 170 175Asn Lys Lys Val Asp Asp Leu Phe Gly Ser Ala Ser Trp Glu Thr Glu

180 185 190Glu Lys Met Ile Lys Ala Lys Leu Ile Thr Pro Asn Asn Lys Lys Arg

195 200 205Ala Phe Asp Lys Arg Glu Val Ile Val Gly Arg Arg Gly Leu Gly Asp

210 215 220Phe Ile Ala Tyr Ala Gly Gln Ala Phe Ile Gly Leu Ile Ala Pro Thr225 230 235 240Arg Ser Gly Lys Gly Val Gly Phe Ile Met Pro Asn Met Ile Asn Tyr

245 250 255Pro Gln Asn Ile Val Val Phe Asp Pro Lys Ala Asp Thr Met Glu Thr

260 265 270Cys Gly Lys Ile Arg Glu Lys Arg Phe Asn Gln Lys Val Phe Ile Tyr

275 280 285Glu Pro Phe Ser Leu Lys Thr His Arg Phe Asn Pro Phe Ala Tyr Val

290 295 300Asp Phe Gly Asn Asp Val Val Leu Thr Glu Asp Ile Leu Ser Gln Ile305 310 315 320Asp Thr Arg Leu Lys Gly His Gly Met Val Ala Ser Gly Gly Asp Phe

325 330 335Ser Thr Gln Ile Phe Gly Leu Ala Lys Leu Val Phe Pro Glu Arg Pro

340 345 350Asn Glu Lys Asp Pro Phe Phe Ser Asn Gln Ala Arg Asn Leu Phe Val

355 360 365Ile Asn Cys Asn Ile Tyr Arg Asp Leu Met Trp Thr Lys Lys Gly Leu

370 375 380Glu Phe Val Lys Arg Lys Lys Ile lle Met Pro Glu Thr Pro Thr Met385 390 395 400Phe Phe Ile Gly Ser Met Ala Ser Gly Ile Asn Leu Ile Asp Glu Asp

405 410 415 Thr Asn Met Glu Lys Val Val Ser Leu Met Glu Phe Phe Gly Gly Glu

420425 430Glu Asp Lys Ser Gly Asp Asn Leu Arg Ala Leu Ser Pro Ala Thr Arg

435 440 445Asn Met Trp Asn Asn Phe Lys Thr Met Gly Gly Ala Lys Glu Thr Tyr

450 455 460Ser Ser Val Gln Gly Val Tyr Thr Ser Ala Phe Ala Pro Tyr Asn Asn465 470 475 480Ala Met Ile Arg Asn Phe Thr Ser Ala Asn Asp Phe Asp Phe Arg Arg

485 490 495Leu Arg Ile Asp Ala Val Ser Ile Gly Val Ile Ala Asn Pro Lys Glu

500 505 510Ser Thr Ile Val Gly Pro Ile Leu Glu Leu Phe Phe Asn Val Met Ile

515 520 525Tyr Ser Asn Leu Ile Leu Pro Ile His Asp Pro Gln Cys Lys Arg Ser

530 535 540Cys Leu Met Leu Met Asp Glu Phe Thr Leu Cys Gly Tyr Leu Glu Thr545 550 555 560Phe Val Lys Ala Val Gly Ile Met Ala Glu Tyr Asn Met Arg Pro Ala

565 570 575Phe Val Phe Gln Ser Lys Ala Gln Leu Glu Asn Asp Pro Pro Leu Gly

580 585 590Tyr Gly Arg Asn Gly Ala Lys Thr Ile Leu Asp Asn Leu Ser Leu Asn

595 600 605Met Tyr Tyr Gly Ile Asn Asn Asp Asn Tyr Tyr Glu His Phe Glu Lys

610 615 620Leu Ser Lys Val Leu Gly Lys Tyr Thr Arg Gln Asp Val Ser Arg Ser625 630 635 640Ile Asp Asp Asn Thr Gly Lys Thr Asn Thr Ser Ile Ser Asn Lys Glu

645650 655Arg Phe Leu Met Thr Pro Asp Glu Leu Met Thr Met Gly Asp Glu Leu

660 665 670Ile Ile Leu Glu Asn Thr Leu Lys Pro Ile Lys Cys His Lys Ala Leu

675 680 685Tyr Tyr Asp Asp Pro Phe Phe Thr Asp Glu Leu Ile Lys Val Ser Pro

690 695 700Ser Leu Ser Lys Lys Tyr Lys Leu Gly Lys Val Pro Asn Gln Ala Thr705 710 715 720Phe Tyr Asp Asp Leu Gln Ala Ala Lys Thr Arg Gly Glu Leu Ser Tyr

725 730 735Asp Lys Ser Leu Val Pro Val Gly Ser Sar Glu Leu

740745 (2) SEQ ID NO:812 information

Sequence properties:

(A) length: 34 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...34

(xi) sequence representation: 812: Leu Ser His Leu Phe Leu Val Lys Arg Pro Tyr Ser Arg Leu Tyr Leu 151015 His Asn Gln Ser Asn His Lys Met Arg His His Ser Ile Leu Phe Val SEQ ID NO

202530 Ser Phe (2) SEQ ID NO:813 information

Sequence properties:

(A) length: 110 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...110

(xi) sequence representation: SEQ ID NO 813: Met Glu His His Lys Ala His Thr Thr Ile Gln Ala Leu Gln Ala Lys 151015 Arg Lys Arg Leu Leu Thr Glu Leu Ala Glu Leu Glu Ala Glu Ile Lys

20 25 30Val Ser Ser Glu Arg Arg Ser Ser Phe Asn Val Ser Leu Ser Pro Ser

35 40 45Leu Leu Ala Glu Ile Glu Glu Ile Glu Tyr Glu Glu Lys Met Ser Lys

50 55 60Glu Arg Arg Ile His His Asn Leu Leu Leu Ser Pro Ser Phe Met Ala65 70 75 80Lys Val Asp Glu Tyr Met Lys Glu Lys Gly Phe Pro Asn Arg Ser Leu

85 90 95Leu Phe Glu Lys Ala Leu Glu Phe Tyr Met Leu Lys His Pro

100105110 (2) SEQ ID NO 814 information

Sequence properties:

(A) length: 158 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...158

(xi) sequence representation: 814: Val Met Arg Phe Phe Ser Phe Cys Tyr Phe Leu Phe Tyr Phe Leu Gly 151015 Val Ser Leu His Ala Leu Ser Pro Leu Glu Glu Gln Glu Phe Leu Ile SEQ ID NO

20 25 30Ser Tyr Arg Leu Lys Ile Val Asp Ser ArG Val Met Gly Glu Glu Tyr

35 40 45Ser Val Ser Lys Pro Ile Val Ser Arg Ile Lys Thr Ala Pro Tyr Val

50 55 60Leu Asp Tyr His Cys Ser Ile Ile Thr Arg Asn Leu Pro Asp Leu Lys65 70 75 80Asn Pro Leu Leu Gln Ile Lys Leu Glu Arg Phe Leu Leu Glu Ile Ala

85 90 95Leu Lys Lys Glu Lys Glu Arg Val Ile Asp Cys Leu Leu Lys Ser Gln

100 105 110Val Ala Ile Thr His Tyr Asp His Ser Tyr Lys Asn Gly Thr Thr Thr

115 120 125Thr Ser Ile Leu Asn Leu Lys Ala Leu Ser Val Lys Ala Ser Leu Glu

130135140 Gly Asp Met Leu Ser Leu Asp Ile Phe Arg Lys Glu Glu Glu 145150155 (2) SEQ ID NO:815 information

Sequence properties:

(A) length: 117 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...117

(xi) sequence representation: 815: Met Glu Leu Ile Lys Lys Leu Glu Lys Glu Ser Glu Val Leu Lys Lys 151015 Asp Leu Gln Gln His Ser Asn Glu Leu Phe Lys Met Leu Ile Ile Asp SEQ ID NO

20 25 30Asn Glu Asp Leu Phe Lys Glu Gln Phe Glu Ile Met Phe Lys Ala Trp

35 40 45Val Glu Ile Val Lys Met Met Phe Glu Leu Thr Lys Lys Thr Lys Phe

50 55 60Asp Gly Glu Met Ile Gly Tyr Thr Glu Glu Leu Leu Thr Phe Leu Val65 70 75 80Arg Asp Phe Phe Asn Gly Ile Phe Lys Ser Lys Val Ile Pro Lys Met

85 90 95Pro Ile Phe Cys Gly Asp Val Lys Cys Glu Asp Phe Asn Ala Leu Arg

100 105 110Ser Leu Val Tyr Leu

115(2) SEQ ID NO 816 information

Sequence properties:

(A) length: 277 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...277

(xi) sequence representation: 816 SEQ ID NO: Leu Lys Arg Ala Leu Trp Leu Ile Leu Gly Leu Phe Tyr Ala Leu Asn 151015 Ala Glu Ser Phe Lys Asp Val Leu Thr Lys Gly Asp Tyr Thr Phe Phe

20 25 30Asn Lys Lys Val Val Ser Pro Ile Lys Arg Tyr Ala Asp Arg Ser Ala

35 40 45Phe Tyr Leu Gly Leu Gly Tyr Gln Leu Gly Ser Ile Gln His Asn Ser

50 55 60Ser Asn Leu Asn Leu Ser Gln Arg Phe Asn Lys Ser Gln Ile Ile Phe65 70 75 80Ser Asp Ser Leu Ser Pro Val Phe Lys Asn Ser Tyr Val Ser Asn Gly

85 90 95Leu Gly Val Gln Val Gly Tyr Lys Trp Val Gly Lys His Glu Glu Thr

100 105 110Lys Trp Phe Gly Phe Arg Trp Gly Leu Phe Tyr Asp Leu Ser Ala Ser

115 120 125Leu Tyr Gly Ser Gln Glu Ser Gln Ser Ile Ile Ile Ser Thr Tyr Gly

130 135 140Thr Tyr Met Asp Leu Leu Leu Asn Ala Tyr Asn Gly Asp Lys Phe Phe145 150 155 160Ala Gly Phe Asn Leu Gly Ile Ala Phe Ala Gly Val Tyr Asp Arg Leu

165 170 175Ser Asp Ala Leu Leu Tyr Gln Thr Leu Leu Gln Ash Thr Phe Gly Gly

180 185 190Lys Val Asn Leu Ash Gly Phe Gln Phe Leu Val Asp Leu Gly Val Arg

195 200 205Leu Gly Ash Glu His Asn Gln Phe Gly Phe GlyIle Lys Ile Pro Thr

210 215 220Tyr Tyr Phe Asn His Tyr Tyr Ser Met Asn Asn Ile Ser Asn Asn Ser225 230 235 240Glu Asn Val Leu Lys Val Leu Arg Phe Leu Glu Tyr Gly Ile Asn Sar

245 250 255Leu Leu Tyr Gln Val Asp Phe Arg Arg Asn Tyr Ser Val Tyr Phe Asn

260 265 270Tyr Thr Tyr Ser Phe

275(2) SEQ ID NO:817 information

Sequence properties:

(A) length: 493 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...493

(xi) sequence representation: 817: Met Pro Ala Leu Asn Ser Ser Lys Asn Met Val Val Asn Ile Asn Gln 151015 Thr Phe Thr Lys Asn Pro Thr Thr Glu Tyr Thr Tyr Pro Asp Gly Asn SEQ ID NO

20 25 30Gly Asn Tyr Tyr Ser Gly Gly Ser Ser Ile Pro Ile Gln Leu Lys Ile

35 40 45Ser Ser Val Asn Asp Ala Glu Asn Leu Leu Gln Gln Ala AIa Thr Ile

50 55 60Ile Asn Val Leu Thr Thr Gln Asn Pro His Val Asn Gly Gly Gly Gly65 7075 80Ala Trp Gly Phe Gly Gly Lys Thr Gly Ash Val Met Asp Ile Phe Gly

85 90 95Asp Ser Phe Ash Ala Ile Asn Glu Met Ile Lys Asn Ala Gln Ala Val

100 105 110Leu Glu Lys Thr Gln Gln Leu Asn Ala Aan Glu Asn Thr Gln Ile Thr

115 120 125Gln Pro Asp Asn Phe Asn Pro Tyr Thr Ser Lys Asp Thr Gln Phe Ala

130 135 140Gln Glu Met Leu Asn Arg Ala Asn Ala Gln Ala Glu Ile Leu Ser Leu145 150 155 160Ala Gln Gln Val Ala Asp Asn Phe His Ser Ile Gln Gly Pro lle Gln

165 170 175Gln Asp Leu Glu Glu Cys Thr Ala Gly Ser Ala Gly Val Ile Asn Asp

180 185 190Asn Thr Tyr Gly Ser Gly Cys Ala Phe Val Lys Glu Thr Leu Ash Ser

195 200 205Leu Glu Gln His Thr Ala Tyr Tyr Gly Asn Gln Val Asn Gln Asp Arg

210 215 220Ala Leu Sar Gln Thr Ile Leu Asn Phe Lys Glu Ala Leu Ser Thr Leu225 230 235 240Gly Asn Asp Ser Lys Ala Ile Asn Ser Gly Ile Ser Asn Leu Pro Asn

245 250 255Ala Lys Ser Leu Gln Asn Met Thr His Ala Thr Gln Asn Pro Asn Ser

260 265 270Pro Glu Gly Leu Leu Thr Tyr Ser Leu Asp Thr Ser Lys Tyr Asn Gln

275 280 285Leu Gln Thr Val Ala Gln Glu Leu Gly Lys Asn Pro Phe Arg Arg Ile

290 295 300Gly Val lle Asn Tyr Gln Asn ASn Asn Gly Ala Met Asn Gly Ile Gly305 310 315 320Val Gln Ala Gly Tyr Lys Gln Phe Phe Gly Lys Lys Arg Asn Trp Gly

325 330 335Leu Arg Tyr Tyr Gly Phe Phe Asp Tyr Asn His Ala Tyr Ile Lys Ser

340 345 350Asn Phe Phe Asn Ser Ala Ser Asp Val Trp Thr Tyr Gly Val Gly Met

355 360 365Asp Ala Leu Tyr Asn Phe Ile Asn Asp Lys Asn Thr Asn Phe Leu Gly

370 375 380Lys Asn Asn Lys Leu Ser Val Gly Leu Pne Gly Gly Phe Ala Leu Ala385 390 395 400Gly Thr Ser Trp Leu Asn Ser Gln Gln Val Asn Leu Thr Met Met Asn

405 413 415Gly Ile Tyr Asn Ala Asn Val Ser Ala Ser Asn Phe Gln Phe Leu Phe

420 425 430Asp Leu Gly Leu Arg Met Asn Leu Ala Arg Pro Lys Lys Lys Asp Ser

435 440 445Asp His Ala Ala Gln His Gly Met Glu Leu Gly Val Lys Ile Pro Thr

450 455 460Ile Asn Thr Asp Tyr Tyr Ser Phe Met Gly Ala Glu Leu Lys Tyr Arg465 470 475 480Arg Leu Tyr Ser Val Tyr Leu Asn Tyr Val Phe Ala Tyr

485490 (2) SEQ ID NO 818 information

Sequence properties:

(A) length: 269 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...269

(xi) sequence representation: 818: Val Leu Asn Thr Thr Gln Lys Ser Leu Leu Val Phe Met Gly Val Phe 151015 Phe Leu Ile Phe Gly Val Asp Gln Ala Ile Lys His Ala Ile Leu Glu SEQ ID NO

20 25 30Gly Phe His Tyr Glu Ser Leu Val Ile Asp Ile Val Leu Val Phe Asn

35 40 45Lys Gly Val Ala Phe Ser Leu Leu Ser Phe Leu Glu Gly Gly Leu Lys

50 55 60Tyr Leu Gln Ile Leu Leu Ile Leu Gly Leu Phe Ile Phe Leu Met Arg65 70 75 80Gln Lys Glu Leu Phe Lys Ser His Ala Ile Glu Phe Gly Met Val Phe

85 90 95Gly Ala Gly Val Ser Asn Val Leu Asn Arg Leu Val Ser Leu Gly Gln

100 105 110Leu Tyr Ile Leu Tyr Asp Val Leu Ala Ile Arg Arg Glu Lys Met Lys

115 120 125Asn Ser Ala Pro Lau Lys Asn Lys Val Phe Cys Gly Leu Tyr Val Leu

130 135 140Ser Leu Ser Ala Ser Val Gln Ala Phe Asp Tyr Lys Ile Glu Val Leu145 150 155 160Ala Glu Ser Phe Ser Lys Val Gly Phe Asn Lys Lys Lys Ile Asp Ile

165 170175Ala Arg Gly Ile Tyr Pro Thr Glu Thr Phe Val Thr Ala Val Gly Gln

180 185 190Gly Asn Ile Tyr Ala Asp Phe Leu Ser Lys Ser Leu Lys Asp Gln Gly

195 200 205His Val Leu Glu Gly Lye Val Gly Gly Thr Ile Gly Gly Ile Ala Tyr

210 215 220Asp Ser Thr Lys Phe Asn Gln Gly Gly Ser Val Ile Tyr Asn Tyr Ile225 230 235 240Gly Tyr Trp Asp Gly Tyr Leu Gly Gly Thr Lys Ala Cys Leu Met Ala

245 250 255Gln Val Ser Met Thr Ala Arg Leu Ala Leu Met Ala Arg

260265 (2) SEQ ID NO 819 information

Sequence properties:

(A) length: 198 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...198

(xi) sequence representation: 819 of SEQ ID NO Met Leu val Thr Lys Leu Ala Pro Asp Phe Lys Ala Pro Ala Val Leu 151015 Gly Asn Asn Glu Val Asp Glu His Phe Glu Leu Ser Lys Asn Leu Gly

20 25 30Lys Asn Gly Val Ile Leu Phe Phe Trp Pro Lys Asp Phe Thr Phe Val

35 40 45Cys Pro Thr Glu Ile Ile Ala Phe Asp Lys Arg Val Lys Asp Phe His

50 55 60Glu Lys Gly Phe Asn Val Ile Gly Val Ser Ile Asp Ser Glu Gln Val65 70 75 80His Phe Ala Trp Lys Asn Thr Pro Val Glu Lys Gly Gly Ile Gly Gln

85 90 95Val Ser Phe Pro Met Val Ala Asp Ile Thr Lys Ser Ile Ser Arg Asp

100 105 110Tyr Asp Val Leu Phe Glu Glu Ala Ile Ala Leu Arg Gly Ala Phe Leu

115 120 125Ile Asp Lys Asn Met Lys Val Arg His Ala Val Ile Asn Asp Leu Pro

130 135 140Leu Gly Arg Asn Ala Asp Glu Met Leu Arg Met Val Asp Ala Leu Leu145 150 155 160His Phe Glu Glu His Gly Glu Val Cys Pro Ala Gly Trp Arg Lys Gly

165 170 175Asp Lys Gly Met Lys Ala Thr His Gln Gly Val Ala Glu Tyr Leu Lys

180 185 190Glu Asn Ser Ile Lys Leu

195(2) SEQ ID NO 820 information

Sequence properties:

(A) length: 215 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...215

(xi) sequence representation: 820: Met Leu Lys Leu Ala Ser Lys Thr Ile Cys Leu Ser Leu Ile Ser Ser 151015 Phe Thr Ala Val Glu Ala Phe Gln Lys His Gln Lys Asp Gly Phe Phe SEQ ID NO

20 25 30Ile Glu Ala Gly Phe Glu Thr Gly Leu Leu Gln Gly Thr Gln Thr Gln

35 40 45Glu Gln Thr Ile Ala Thr Thr Gln Glu Lys Pro Lys Pro Lys Pro Lys

50 55 60Pro Lys Pro Ile Thr Pro Gln Ser Thr Tyr Gly Lys Tyr Tyr Ile Ser65 70 75 80Gln Ser Thr Ile Leu Lys Asn Ala Thr Glu Leu Phe Ala Glu Asp Asn

85 90 95Ile Thr Asn Leu Thr Phe Tyr Ser Gln Asn Pro Val Tyr Val Thr Ala

100 105 110Tyr Asn Gln Glu Ser Ala Glu Glu Ala Gly Tyr Gly Asn Asn Ser Leu

115 120 125Ile Met Ile Gln Asn Phe Leu Pro Tyr Asn Leu Asn Asn Ile Glu Leu

130 135 140Ser Tyr Thr Asp Asp Gln Gly Asn Val Val Ser Leu Gly Val Ile Glu145 150 155 160Thr Ile Pro Lys Gln Ser Gln Ile Ile Leu Pro Ala Ser Leu Phe Asn

165 170 175Asp Pro Gln Leu Asn Ala Asp Gly Ser Asn Asn Ser Lys Pro Thr Pro

180 185 190His Asp Phe Leu Met Pro Ala Arg Arg Ile Cys Leu Thr Ser Ser Ala

195 200 205Arg Leu Gln Pro Ile Phe Lys

210215 (2) SEQ ID NO 821 information

Sequence properties:

(A) length: 168 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...168

(xi) sequence representation: 821: Met Leu Ser Ser Asn Asp Leu Phe Met Val Val Leu Gly Ala Ile Leu 151015 Leu Val Leu Val Cys Leu Val Gly Tyr Leu Tyr Leu Lys Glu Lys Glu SEQ ID NO

20 25 30Phe Tyr His Lys Met Arg Arg Leu Glu Lys Thr Leu Asp Glu Ser Tyr

35 40 45Gln Glu Asn Tyr Leu Tyr Ser Lys Arg Leu Arg Glu Leu Glu Gly Arg

50 55 60Leu Glu Gly Leu Ser Leu Glu Lys Ser Ala Lys Glu Asp Ser Ser Leu65 70 75 80Lys Thr Thr Leu Ser His Leu Tyr Asn Gln Leu Gln Glu Ile Gln Lys

85 90 95Ser Met Asp Lys Glu Arg Asp Tyr Leu Glu Glu Lys Ile Ile Thr Leu

100 105 110Glu Asn Lys Phe Lys Asp Met Gly His Tyr Ala Ala Ser Asp Glu Val

115 120 125Asn Glu Lys Gln Val Leu Lys Met Tyr Gln Glu Gly Tyr Ser Val Asp

130 135 140Ser Ile Ser Lys Glu Phe Lys Val Ser Lys Gly Glu Val Glu Phe Ile145 150 155 160Leu Asn Met Ala Gly Leu Lys Trp

165(2) SEQ ID NO 822 information

Sequence properties:

(A) length: 338 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...338

(xi) sequence representation: 822 of SEQ ID NO: Val Gly Phe Glu Tyr Ser Ile Ser His Ala Val Glu His Asn Asn Pro 151015 Phe Leu Asp Gln Glu Arg Ile Gln Ala Ile Ser Asn Ala Arg Gly Glu

20 25 30Val Cys Gly Leu Asp Arg Val Lys Asn Glu Ile Thr Asp Met Pro Asn

35 40 45Thr Phe Asn Tyr Ile Asn Asn Ala Leu Lys Asn Asn Ala Lys Leu Thr

50 55 60Pro Thr Glu Lys Gln Ala Glu Thr Tyr Tyr Leu Gln Ser Thr Leu Gln65 70 75 80Asn Ile Glu Lys Ile Val Met Leu Ser Gly Gly Val Ala Ser Asn Pro

85 90 95Lys Leu Ala Gln Ala Leu Glu Lys Met Gln Glu Pro Ile Thr Asn Pro

100 105 110Leu Glu Leu Val Glu Asn Leu Lys Asn Leu Glu Leu Gln Phe Ser Gln

115 120 125Ser Gln Asn Ser Met Leu Ser Ser Leu Ser Ser Gln Ile Ala Gln Ile

130 135 140Ser Asn Ser Leu Asn Ala Leu Asp Pro Ser Ser Tyr Ser Lys Asn Val145 150 155 160Ser Ser Met Tyr Gly Val Gly Leu Ser Val Gly Tyr Lys His Phe Phe

165 170 175Thr Lys Lys Lys Asn Gln Gly Phe Arg Tyr Tyr Leu Phe Tyr Asp Tyr

180 185 190Gly Tyr Thr Asn Phe Gly Phe Val Gly Asn Gly Phe Asp Gly Leu Gly

195 200 205Lys Met Asn Asn His Leu Tyr Gly Leu Gly Ile Asp Tyr Leu Phe Asn

210 215 220Phe Ile Asp Asn Ala Gln Lys His Ser Ser Val Gly Phe Tyr Val Gly225 230 235 240Phe Ala Leu Ala Gly Ser Ser Trp Val Gly Ser Gly Leu Gly Met Trp

245 250 255Val Ser Gln Met Asp Phe Ile Asn Asn Tyr Leu Thr Asp Tyr Arg Ala

260 265 270Lys Met His Thr Ser Phe Phe Gln Ile Pro Leu Asn Phe Gly Val Arg

275 280 285Val Asn Val Asp Arg His Asn Gly Phe Glu Met Gly Leu Lys Ile Pro

290 295 300Leu Ala Val Asn Ser Phe Tyr Glu Thr His Gly Lys Gly Leu Asn Ala305 310 315 320Ser Leu Phe Phe Lys Arg Leu Val Met Phe Asn Val Ser Tyr Val Tyr

325330335 Ser Phe (2) SEQ ID NO:823 information

Sequence properties:

(A) length: 80 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...80

(xi) sequence representation: SEQ ID NO 823: Met Met Phe Glu Leu Thr Lys Lys Thr Lys Phe Asp Gly Glu Met Ile 151015 Gly Tyr Thr Glu Glu Leu Leu Thr Phe Leu Val Arg Asp Phe Phe Asn

20 25 30Gly Ile Phe Lys Ser Lys Val Ile Pro Lys Met Pro Ile Phe Cys Gly

35 40 45Asp Val Lys Cys Glu Asp Phe Asn Ala Leu Arg Ser Leu Val Tyr Leu

505560 Ser Val Leu Glu Leu Glu Glu Thr Ile Asn Pro Asn Lys Ile Pro Phe 65707580 (2) SEQ ID NO:824 information

Sequence properties:

(A) length: 200 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B)Position: 1...200

(xi) sequence representation: SEQ ID NO 824: Val Gln Leu Leu Lys Asp Ash Lys Glu Val Val Val Leu Asp Thr Asp 151015 Ser Gln Lys Ser Met Glu Thr Phe Ala Thr Ile Arg Ala Glu Lys Glu

20 25 30Arg Pro Thr Phe Ser Leu Phe Asn Arg Ser Ser Gly Phe Ser Asp Tht

35 40 45Leu Lys Gln Met Val Ser Lys Tyr Glu Asn Ile Leu Ile Asp Thr Lys

50 55 60Gly Glu Tyr Ser Lys Glu Thr Gln Lys Ala Met Leu Leu Ser Asn Ile65 70 75 80Val Leu Val Pro Thr Thr Pro Ser Gln Leu Asp Thr Glu Val Leu Ala

85 90 95Asn Met Leu Glu Arg Ile Glu Gln Leu Gln Glu Leu Asn Glu Asn Leu

100 105 110Arg Ala Leu Ile Val Ile Asn Arg Met Pro Thr Ile Pro Thr Leu Lys

115 120 125Glu Arg Gln Ala Leu Ile Glu Phe Ile Lys Glu Asn Asn Pro Ser Asp

130 135 140Arg Ile Thr Leu Leu Glu Ser Ser Leu Ser Glu Arg Ile Val Tyr Lys145 150 155 160Arg Ser Val Ser Glu Gly Leu Gly Val Ile Glu Tyr Ser Asp Lys Lys

165 170 175Ala Ile Asn Glu Trp Val Asn Phe Tyr Asn Glu Leu Lys Ser His Leu

180 185 190Glu Lys Glu Lys Ile His Thr Phe

195200 (2) SEQ ID NO 825 information

Sequence properties:

(A) length: 70 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...70

(xi) sequence representation: SEQ ID NO 825: Met Arg Ser Asp Val Glu Val Leu Ser Pro Leu His Lys Ile Asp Glu 151015 Lys Tyr Leu Phe His Leu Lys Ile Ala Gly Glu Leu Ala Ser Met Gly

20 25 30Lys Ile Leu Ser Val Tyr Leu Ala His Lys His Ser Ala Tyr Phe Ile

35 40 45Leu Asn Ala Leu Ser Tyr Gly Phe Ser His Gln Asp Arg Ala Ile Ile

505560 Cys Leu Leu Gly Ala Ile 6570 (2) SEQ ID NO:826 information

Sequence properties:

(A) length: 70 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...70

(xi) sequence representation: SEQ ID NO:826: Met Ser Ala Met Met Pro Ser Leu Leu Thr Leu Gln TrpLeu Ser Phe 151015 Ile Leu Ser Leu Ala Glu Asn Leu Cys Leu Thr Asp Ser His His Leu

20 25 30Lys Tyr Thr Leu Glu Lys Asn Lys Leu Val Ile His Ser Asn Asp Ala

35 40 45Leu Tyr Leu Ala Lys Glu Met Leu Pro Lys Leu Ile Lys Pro Ile Pro

505560 Leu Thr Ile Glu Phe Ala 6570 (2) SEQ ID NO:827 information

Sequence properties:

(A) length: 478 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...478

(xi) sequence representation: SEQ ID NO 827: Leu Lys Lys Ile Ala Leu Ile Leu Asp Gly Ile Val Ala Lys Asn Phe 151015 Leu Asp Leu Val Leu Arg His Tyr Ser Asn His Asn Phe Tyr Ile Val

20 25 30Val Val Lys Asp Glu Ser Leu Ile Pro Lys Asn Tyr Pro Ser Thr Phe

35 40 45Ala Phe His Cys Phe Asp Ala Thr Ser Ser Phe Arg Leu Leu Gln Val

50 55 60Leu Asn Asp Glu Val Ser Asp Ala Phe Leu Ile Ile Gln Asp Phe Lys65 70 75 80Glu Gln Arg Ile Ile His Lys Ile Ile Gln Thr His Phe Lys Arg Met

85 90 95Arg Val Val Leu Ser Val Lys Aru Asp Ser Glu Lys Thr Leu Glu Asn

100 105 110Asn Glu Glu Asn Lys Asp Glu Lys Leu Ile Leu Ile Asp Glu Phe Glu

115 120 125Val Leu Ala Asn Lys Phe Ile Ser Arg Leu Pro Asn Ile Pro Ser Thr

130 135 140Pro Arg Glu Phe Gly Leu Gly Lys Gly Glu Ile Met Glu Ile Asp Val145 150 155 160Pro Phe Gly Ser Ile Phe Ala Tyr Arg His Ile Gly Ser Ile Arg Gln

165 170 175Lys Glu Tyr Arg Ile Val Gly Leu Tyr Arg Asn Asp Val Leu Leu Leu

180 185 190Ser Thr Lys Ser Leu Val Ile Gln Pro Arg Asp Ile Leu Leu Val Ala

195 200 205Gly Asn Pro Glu Ile Leu Asn Ala Val Tyr His Gln Val Lys Ser Asn

210 215 220Val Gly Gln Phe Pro Ala Pro Phe Gly Lys Ser Ile Tyr Leu Tyr Ile225 230 235 240Asp Met Arg Leu Gln Ser Arg Lys Ala Met Met Arg Asp Val Tyr Gln

245 250 255Ala Leu Phe Leu His Lys Arg Leu Lys Ser Tyr Lys Leu Tyr Ile Gln

260 265 270Val Leu His Pro Thr Ser Pro Lys Phe Tyr Mis Lys Phe Leu Ser Leu

275 280 285Glu Thr Glu Ser Ile Glu Val Asn Phe Asp Phe Tyr Gly Lys Ser Phe

290 295 300Ile Gln Lys Leu His Glu Asp His Gln Lys Lys Met Gly Leu Ile Val305 310 315320Val Gly Arg Glu Leu Phe Phe Leu Lys Lys His Arg Arg Ala Leu His

325 330 335Lys Thr Ala Thr Pro Val Tyr Lys Thr Asn Thr Ser Gly Leu Ser Lys

340 345 350Thr Thr Gln Ser Ile Val Val Leu Asn Glu Ser Leu Ser Ile Asn Glu

355 360 365Asp Met Ser Ser Val Ile Phe Asp Val Ser Met Gln Met Asp Leu Gly

370 375 380Leu Leu Leu Tyr Asp Phe Asp Pro Asn Lys His Tyr Lys Asn Glu Ile385 390 395 400Val Asn His Tyr Glu Asn Leu Ala Asn Thr Phe Asn Arg Lys Ile Glu

405 410 415Ile Phe Gln Thr Asp Ile Lys Asn Pro Ile Met Tyr Leu Asn Ser Leu

420 425 430Arg Asn Pro Ile Leu His Phe Met Pro Phe Glu Glu Cys Ile Thr Gln

435 440 445Thr Arg Tyr Leu Trp Phe Leu Ser Thr Lys Val Glu Lys Leu Ala Phe

450455460 Leu Asn Asp Asp His Pro Gln Ile Phe Ile Pro Val Ala Glu 465470475 (2) SEQ ID NO:828 information

Sequence properties:

(A) length: 418 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...418

(xi) sequence representation: 828 SEQ ID NO: Met Lys Lys Val Tyr Phe Lys Thr Phe Gly Cys Arg Thr Asn Leu Phe 151015 Asp Thr Gln Val Met Gly Glu Asn Leu Lys Asp Phe Ser Ala Thr Leu

20 25 30Glu Glu Gln Glu Ala Asp Ile Ile Ile Ile Asn Ser Cys Thr Val Thr

35 40 45Asn Gly Thr Asp Ser Ala Val Arg Ser Tyr Ala Arg Lys Met Ala Arg

50 55 60Leu Asp Lys Glu Val Leu Phe Thr Gly Cys Gly Val Lys Thr Gln Gly65 70 75 80Lys Glu Leu Phe Glu Lys Gly Leu Leu Lys Gly Val Phe Gly His Asp

85 90 95Asn Lys Glu Lys Ile Asn Ala Leu Leu Gln Glu Lys Lys Arg Phe Phe

100 105 110Ile Asp Asp Asn Leu GLu Asn Lys His Leu Asp Thr Thr Met Val Ser

115 120 125Glu Phe Val Gly Lys Thr Arg Ala Phe Ile Lys Ile Gln Glu Gly Cys

130 135 140Asp Phe Asp Cys Asn Tyr Cys Ile Ile Pro Ser Val Arg Gly Arg Ala145 150 155 160Arg Ser Phe Glu Glu Arg Lys Ile Leu Glu Gln Val Gly Leu Leu Cys

165 170 175Ser Lys Gly Val Gln Glu Val Val Leu Thr Gly Thr Asn Val Gly Ser

180 185 190Tyr Gly Lys Asp Arg Gly Ser Asn Ile Ala Arg Leu Ile Lys Lys Leu

195 200 205Ser Gln Ile Thr Gly Leu Lys Arg Ile Arg Ile Gly Ser Leu Glu Pro

210 215 220Asn Gln Ile Asn Asp Glu Phe Leu Glu Leu Leu Glu Glu Asp Phe Leu225 230 235 240Glu Lys His Leu His Ile Ala Leu Gln His Ser His Asp Phe Met Leu

245 250 255Glu Arg Met Asn Arg Arg Asn Arg Thr Lys Ser Asp Arg Glu Leu Leu

260 265 270Glu Ile Ile Ala Ser Lys Asn Phe Ala Ile Gly Thr Asp Phe Ile Val

275 280 285Gly His Pro Gly Glu Ser Glu Ser Val Phe Glu Lys Ala Phe Lys Asn

290 295 300Leu Glu Ser Leu Pro Leu Thr His Ile His Pro Phe Ile Tyr Ser Lys305 310 315 320Arg Lys Asp Thr Pro Ser Ser Leu Met Arg Asp Ser Val Ser Leu Glu

325 330 335Asp Ser Lys Lys Arg Leu Asn Ala Ile Lys Asp Leu Ile Phe His Lys

340 345 350Asn Lys Ala Phe Arg Gln Leu Gln Leu Lys Leu Asn Thr Pro Leu Lys

355 360 365Ala Leu Val Glu Ala Gln Lys Asp Gly Glu Phe Lys Ala Leu Asp Gln

370 375 380Phe Phe Asn Pro Ile Lys Ile Lys Ser Asp Lys Pro Leu Arg Ala Ser385 390 395 400Phe Leu Glu Ile Lys Glu Tyr Glu tle Lys Glu Arg Glu Asn His Ala

405410415 ValPhe (2) SEQ ID NO 829 information

Sequence properties:

(A) length: 175 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...175

(xi) sequence representation: SEQ ID NO 829 Leu Lys Ile Ala Tyr Arg Leu Leu Gly Leu Mer Ser Phe Ile Ala Leu 151015 Val Leu Ala Ile Val Leu Ile Ser Ile Leu Pro Leu Gln Lys Thr Glu

20 25 30His His Phe Val Asp Phe Leu Asn Gln Asp Lys His Tyr Ala Ile Ile

35 40 45Gln Arg Ala Asp Lys Ser Ile Ser Ser Asn Glu Ala Leu Ala Arg Ser

50 55 60Leu Ile Gly Ala Tyr Val Leu Asn Arg Glu Ser Ile Asn Arg Ile Asp65 70 75 80Asp Lys Ser Arg Tyr Glu Leu Val Arg Leu Gln Ser Ser Ser Lys Val

85 90 95Trp Gln Arg Phe Glu Asp Leu Ile Lys Ala Gln Asn Ser Ile Tyr Val

100 105 110Gln Ser His Leu Glu Arg Glu Val His Ile Val Asn Ile Ala Ile Tyr

115 120 125Gln Gln Asp Asn Asn Pro Ile Ala Ser Val Ser Ile Ala Ala Lys Leu

130 135 140Leu Asn Glu Asn Lys Leu Val TTr Glu Lys Arg Tyr Lys Ile Val Leu145 150 155 160Ser Tyr Leu Phe Asp Thr Pro Asp Phe Asp Tyr Ala Ser Met Pro

165170175 (2) SEQ ID NO 830 information

Sequence properties:

(A) length: 186 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...186

(xi) sequence representation: 830: Leu Leu Leu Val Ser Arg Phe Leu Asn Ala Ile Asp Pro Phe Asn Leu 151015 Gly Val Leu Leu Ser Arg Phe Gln Ile Lys Asn Gly Cys Ile Tyr Gly SEQ ID NO

20 25 30Val Cys Ser Tyr Lys Val Ser Lys Phe Thr Pro Gly Tyr Glu Glu Ser

35 40 45Lys Ala Arg Val Leu Asn Ala Leu Asn Ile Leu Ser Lys His Gln Ile

50 55 60Trp Gln Ser Asn Gln Glu Ser Val Thr Lys Val Lys Gly Thr Pne Val65 70 75 80Phe Ile Leu Glu Asn Asp Leu His Leu Asp Glu Asn Ser Phe Tyr Lys

85 90 95Lys Leu Leu Asn Leu Ile Ile Asp Asn Asp Phe Phe Asn Arg Ser His

100 105 110Leu Val Thr Pro Ser Asn Gly Thr Asn Ser His Pro Glu Leu His Arg

115 120 125Ser Ile Thr Pro Arg Glu Ala Ala Arg Ile Gln Ser Phe Ser Asp Asp

130 135 140Tyr Ile Phe Tyr Gly Asn Lys Thr Ser Val Cys Lys Gln Ile Gly Asn145 150 155 160Ala Val Pro Pro Leu Leu Ala Leu Ala Leu Gly Lys Ala Ile Leu Lys

165 170 175Ser Ala Arg Asn Asp Thr Asn Pro Ser Arg

180185 (2) SEQ ID NO 831 information

Sequence properties:

(A) length: 173 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...173

(xi) sequence representation: SEQ ID NO 831: Met Gly Leu Lys Asn Lys Ile Lys Gly Phe Val Lys Glu Arg Met Pro 151015 Phe Val Met Arg Cys Val Arg Gly Leu Lys Gly Ala Lys Asp Thr His

20 25 30Glu Asn Ala His Asp Arg Asp Ala Tyr Cys Gly Ile Asn Arg Glu Ile

35 40 45Lys Glu Met Leu Glu Ala Lys Lys Leu His Phe Leu Gln Glu Lys Ala

50 55 60Leu Phe Asn Hls Asp His Gln Glu Ser Val Phe Leu Ala Ile Ala Ser65 70 75 80Leu Asn Asn Glu Ser Phe Ile Glu Tyr Asn Lys Ser Ile Tyr Lys Asn

85 90 95Ser Ser Leu Asn Tyr Asn Tyr Gly Gly His Leu Glu Asp Arg Val Ile

100 105 110His Pro Thr Leu Thr Leu Pro Asn Pro Thr His Ser Gly Tyr Phe Asp

115 120 125Tyr Asp Lys Lys Ser Gln Asn Pro Lys Ser Pro Leu Asn Pro Trp Ala

130 135 140Phe Ile Arg Val Lys Asn Glu Ile Val Thr Leu Glu Glu Ser Leu Phe145 150 155 160Ser Met Leu Pro Ala Val Gln Arg Gly Gly His Trp Phe

165170 (2) information SEQ ID NO 832

Sequence properties:

(A) length: 175 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...175

(xi) sequence representation: 832 SEQ ID NO: Leu Trp His Gln Leu Tyr His Tyr Cys Asn Tyr Thr Leu Ser Phe Ile 151015 Pro Lys Asn Glu Trp Val Val Lys Ile Asp Cys Asp His Ile Tyr Asp

20 25 30Ala Lys Lys Leu Tyr Lys Ser Phe Tyr Ile Pro Lys Asn Ile Lys Glu

35 40 45Val Val Met Tyr Ser Arg Ile Asn Phe Val Val Arg Asp Phe Glu Val

50 55 60Phe Val Arg Asn Asp Gly Asp Phe Gly Phe Leu Asp Ala Trp Gly Asp65 70 75 80His Trp Leu Leu Tyr Asn Asp Cys Glu Pro Phe Glu Ile Trp Arg Tyr

85 90 95Asn Asp Glu Ser Tyr Glu Val Leu Lys Leu Lys Asp Lys His His Ile

100 105 110Lys Asp Lys Glu Met Val Gln Trp His Phe Pro Leu Ala Lys Lys Arg

115 120 125Arg Asn Ala Ile Val Tyr Asp Asp Leu Ile Pro Leu Glu Glu Phe Lys

130 135 140Lys Arg His Ala Asp Leu Ile Gly Thr Arg Ile Glu Glu Ser Met Leu145 150 155 160Asp Glu Lys Arg Ile Leu Glu Val Tyr Gln Lys Phe Arg Leu Pro

165170175 (2) SEQ ID NO:833 information

Sequence properties:

(A) length: 357 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...357

(xi) sequence representation: SEQ ID NO. 833: Met Gln Lys Pro Gln Asn Lys Pro Ser Ser Ser Gln Gln Ser Pro Gln 151015 Asn Phe Ser Tyr Pro Glu Ser Lys Leu Gly Ser Lys Asn Ser Lys Asn

20 25 30Ser Leu Leu Gln Pro Leu Val Thr Pro Ser Lys Val Ser Pro Thr Asn

35 40 45Glu Val Lys Thr Pro Thr Asn Asp Ala Asn Pro Pro Leu Lys His Ser

50 55 60Ser Gln Asp Gln Glu Asn Asn Leu Phe Val Ala Pro Pro Thr Glu Lys65 70 75 80Thr Leu Pro Asn Asn Thr Ser Ser Ala Asp Ala Ser Glu Asn Asn Glu

85 90 95Ser Asn Glu Asn Arg Asp Asn Val Glu Lys Gln Ala Ile Arg Asp Pro

100 105 110Asn Ile Lys Glu Phe Ala Cys Gly Lys Trp Val Tyr Asp Asp Glu Asn

115 120 125Leu Gln Ala Tyr Arg Pro Ser Ile Leu Lys Arg Val Asp Lys Asp Lys

130 135 140Glu Ile Thr Thr Asp Ile Thr Pro Cys Asp Tyr Ser Thr Ala Glu Asn145 150 155 160Lys Ser Gly Lys Ile Ile Thr Pro Tyr Thr Lys Ile Ser Val His Lys

165 170 175Thr Glu Pro Leu Glu Asp Pro Gln Thr Phe Glu Ala Lys Asn Asn Phe

180 185 190Ala Ile Leu Gln Ala Arg Ser Ser Thr Glu Lys Cys Lys Arg Ala Arg

195 200 205Ala Arg Lys Asp Gly Thr Thr Arg Gln Cys Tyr Leu Ile Glu Glu Pro

210 215 220Leu Lys Gln Ala Trp Glu Ser Glu Tyr Glu Ile Thr Thr Gln Leu Val225 230 235 240Lys Ala Ile Tyr Glu Arg Pro Lys Gln Asp Asp Gln Val Glu Pro Thr

245 250 255Phe Tyr Glu Thr Ser Glu Leu Ala Tyr Ser Ser Thr Arg Lys Ser Glu

260 265 270Ile Thr Arg Asn Glu Leu Asn Leu Asn Glu Lys Phe Met Glu Phe Val

275 280 285Glu Val Tyr Glu Gly His Tyr Leu Asn Asp Ile Ile Lys Glu Ser Ser

290 295 300Glu Tyr Lys Glu Trp Val Lys Asn His Val Arg Phe Lys Glu Gly Val305 310 315 320Cys Met Ala Leu Glu Ile Glu Glu Gln Pro Arg Ala Lys Ser Thr Pro

325 330 335Leu Ser Ile Glu Asn Ser Arg Val Val Cys Val Lys Lys Gly Asn Tyr

340 345 350Leu Phe Asn Glu Val

355(2) SEQ ID NO 834 message

Sequence properties:

(A) length: 143 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...143

(xi) sequence representation: 834, Ile Gln Tyr Pro Lys Ser Ser Phe Phe Gln Lys Arg Gly Arg Asn Gly 151015 Asn His Ser Thr Ile Gln Pro Phe Asn His Ser Thr Ile Gln Pro Phe SEQ ID NO

20 25 30Asn His Ser Ile Ile Gln Ser Phe Asn His Ser Ile Ile Gln Ser Phe

35 4045Asn His Ser Ile Ile Gln Ser Phe Asn His Ser Thr Ile Gln Ala Thr

50 55 60Leu Pro Tyr Phe Tyr Asn Tyr Leu Ser Phe Tyr Lys Asn Leu Phe Lys65 70 75 80Asn Pro Leu Phe Phe Ile Ile Pro Pro Phe Ile Asn Pro Phe Ile Asn

85 90 95Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn

100 105 110Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn

115 120 125Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile

130135140 (2) SEQ ID NO 835 information

Sequence properties:

(A) length: 242 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...242

(xi) sequence representation: SEQ ID NO 835: Leu Lys Val Asn Phe Phe Ala Thr Cys Leu Gly Ala Ala Ile Tyr Ser 151015 Asn Ala Ser Leu Asn Ala Ile Lys Leu Leu Arg Lys Glu Asn Leu Glu

20 25 30Val Val Phe Lys Lys Asp Gln Thr Cys Cys Gly Gln Pro Ser Tyr Asn

35 4045Ser Gly Tyr Tyr Glu Glu Thr Lys Lys Val Val Leu Tyr Asn Ile Lys

50 55 60Leu Tyr Ser Asn Asn Asp Tyr Pro Ile Ile Leu Pro Ser Gly Ser Cys65 70 75 80Thr Gly Met Met Arg His Asp Tyr Leu Glu Leu Phe Glu Gly His Ala

85 90 95Glu Phe Asn Met Val Lys Asp Phe Cys Ser Arg Val Tyr Glu Leu Ser

100 105 110Glu Phe Leu Asp Lys Lys Leu Gln Val Lys Tyr Glu Asp Lys Gly Glu

115 120 125Pro Leu Lys Ile Thr Trp His Ser Asn Cys His Ala Leu Arg Val Ala

130 135 140Lys Val Ile Asp Ser Ala Lys Asn Leu Ile Arg Gln Leu Lys Asn Val145 150 155 160Glu Leu Ile Glu Leu Glu Lys Glu Glu Glu Cys Cys Gly Phe Gly Gly

165 170 175Thr Phe Ser Val Lys Glu Pro Glu Ile Ser Ala Val Met Val Lys Glu

180 185 190Lys Ile Lys Asp Ile Glu Ser Arg His Val Asp Val Ile Val Ser Ala

195 200 205Asp Ala Gly Cys Leu Met Asn Ile Ser Thr Ala Met Gln Lys Met Gly

210215220 Set Leu Thr Lys Pro Met His Phe Tyr Asp Phe Leu Ala Ser Arg Leu 225230235240 Gly Leu (2) SEQ ID NO 836 information

Sequence properties:

(A) length: 401 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...401

(xi) sequence representation: SEQ ID NO 836: Met Ile Phe Gly Asp Phe Lys Tyr Gln Lys Ser Val Lys Lys Leu Thr 151015 Ala Thr Asn Leu Asn Glu Leu Lys Asn Ala Leu Asp Phe Ile Ser Gln

20 25 30Asn Arg Gly Lys Gly Tyr Phe Val Gly Tyr Leu Leu Tyr Glu Ala Arg

35 40 45Leu Ala Phe Leu Asp Glu Asn Phe Gln Ser Gln Thr Pro Phe Leu Tyr

50 55 60Phe Glu Gln Phe Leu Glu Arg Lys Lys Tyr Pro Leu Glu Pro Leu Lys65 70 75 80Glu His Ala Phe Tyr Pro Lys Ile His Ser Ser Leu Asp Gln Lys Thr

85 90 95Tyr Phe Lys Gln Phe Lys Ala Val Lys Glu His Leu Lys Asn Gly Asp

100 105 110Thr Tyr Gln Val Asn Leu Thr Met Asp Leu Leu Leu Asn Thr Lys Ala

115 120 125Lys Pro Lys Arg Val Phe Lys Glu Val Ile His Asn Gln Ash Thr Pro

130 135 140Phe Lys Ala Phe Ile Glu Asn Glu Phe Gly Ser Val Leu Ser Phe Ser145 150 155 160Pro Glu Leu Phe Phe Glu Leu Glu Phe Leu Asp Thr Ala Ile Lys Ile

165 170 175Ile Thr Lys Pro Met Lys Gly Thr Ile Ala Arg Ser Asn Asn Pro Leu

180 185 190Ile Asp Glu Lys Asn Arg Leu Phe Leu Gln Asn Asp Asp Lys Asn Arg

195 200 205Ser Glu Asn Val Met Ile Val Asp Leu Leu Arg Asn Asp Leu Ser Arg

210 215 220Leu Ala Leu Lys Asn Ser Val Lys Val Asn Gln Leu Phe Glu Ile Ile225 230 235 240Ser Leu Pro Ser Val Tyr Gln Met Ile Ser Glu Ile Glu Ala Gln Leu

245 250 255Pro Leu Lys Thr Ser Leu Phe Glu Ile Phe Lys Ala Leu Phe Pro Cys

260 265 270Gly Ser Val Thr Gly Cys Pro Lys Ile Lys Thr Met Gln Ile Ile Glu

275 280 285Ser Leu Glu Lys Arg Pro Arg Gly Val Tyr Cys Gly Ala Ile Gly Met

290 295 300Val Gly Gly Lys Lys Ala Leu Phe Ser Val Pro Ile Arg Thr Leu Glu305 310 315 320Lys Arg Ala His Glu Asp Phe Leu His Leu Gly Val Gly Ser Gly Val

325 330 335Thr Tyr Lys Ser Lys Ala Ser Lys Glu Tyr Glu Glu Ser Phe Leu Lys

340 345 350Ser Phe Phe Val Met Pro Lys Ile Glu Phe Glu Ile Val Glu Thr Met

355 360 365Arg Val Ile Lys Arg Asp Gln Lys Leu Glu Ile Asn Asn Lys Asn Ala

370375380 His Lys Glu Arg Leu Met His Ser Ala Gln Tyr Phe Asn Phe Lys Tyr 385390395400 Arg (2) SEQ ID NO:837 message

Sequence properties:

(A) length: 264 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...264

(xi) sequence representation: SEQ ID NO:837: Met Lys Ile Ser Val Ser Lys Asn Asp Leu Glu Asn Thr Leu Arg Tyr 151015 Leu Gln Ala Phe Leu Asp Lys Lys Asp Ala Ser Ser Ile Ala Ser His

20 25 30Ile His Leu Glu Val Ile Lys Glu Lys Leu Phe Leu Lys Ala Ser Asp

35 40 45Ser Asp Ile Gly Leu Lys Ser Tyr Ile Ser Thr Gln Ser Thr Asp Lys

50 55 60Glu Gly Val Gly Thr Ile Asn Gly Lys Lys Phe Leu Asp Ile Ile Ser65 70 75 80Cys Leu Lys Asp Ser Asn Ile Val Leu Glu Thr Lys Asp Asp Ser Leu

85 90 95Val Ile Lys Gln Asn Lys Ser Ser Phe Lys Leu Pro Met Phe Asp Ala

100 105 110Asp Glu Phe Pro Glu Phe Pro Val Ile Asp Pro Lys Val Ser Leu Glu

115 120 125Ile Asn Ala Pro Phe Leu Val Asp Ala Phe Lys Lys Ile Ala Pro Val

130 135 140Ile Glu Gln Thr Ser His Lys Arg Glu Leu Ala Gly Val Leu Met Gln145 150 155 160PheAsn Gln Lys His Gln Thr Leu Ser Val Val Gly Thr Asp Thr Lys

165 170 175Arg Leu Ser Tyr Thr Gln Leu Glu Lys Ile Ser Ile His Ser Thr Glu

180 185 190Glu Asp Ile Ser Cys Ile Leu Pro Lys Arg Ala Leu Leu Glu Ile Leu

195 200 205Lys Leu Phe Tyr Glu Asn Phe Ser Phe Lys Ser Asp Gly Met Leu Ala

210 215 220Val Val Glu Asn Glu Thr His Ala Phe Phe Thr Lys Leu Ile Asp Gly225 230 235 240Asn Tyr Pro Asp Tyr Gln Lys Ile Leu Pro Lys Glu Tyr Thr Ser Ser

245 250 255Phe Thr Leu Gly Lys Glu Glu Phe

260(2) SSEQ ID NO:838 information

Sequence properties:

(A) length: 312 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...312

(xi) sequence representation: 838: Leu Asn Asn Leu Glu Pro Leu Gly Ala Glu Val Phe Val Gly Leu Asp 151015 Gly Ile Asp Ala Met Ile Glu Glu Cys Val Ser Asn Leu Val Ile Asn SEQ ID NO

20 25 30Ala Ile Val Gly Val Ala Gly Leu Lys Ala Ser Phe Lys SerLeu Gln

35 40 45Arg Asn Lys Lys Leu Ala Leu Ala Asn Lys Glu Ser Leu Val Ser Ala

50 55 60Gly His Leu Leu Asp Ile Ser Gln Ile Thr Pro Val Asp Ser Glu His65 70 75 80Phe Gly Leu Trp Ala Leu Leu Gln Asn Lys Thr Leu Lys Pro Lys Ser

85 90 95Leu Ile Ile Ser Ala Ser Gly Gly Ala Phe Arg Asp Thr Pro Leu Asp

100 105 110Leu Ile Ala Ile Gln Asn Ala Gln Asn Ala Leu Lys His Pro Asn Trp

115 120 125Ser Met Gly Asp Lys Ile Thr Ile Asp Ser Ala Ser Met Val Asn Lys

130 135 140Leu Phe Glu Ile Leu Glu Thr Tyr Trp Leu Phe Gly Ala Ser Leu Lys145 150 155 160Ile Asp Ala Leu Ile Glu Arg Ser Ser Ile Val His Ala Leu Val Glu

165 170 175Phe Glu Asp Asn Ser Val Ile Ala His Leu Ala Ser Ala Asp Met Gln

180 185 190Leu Pro Ile Ser Tyr Ala Ile Asn Pro Lys Leu Ala Ser Leu Ser Ala

195 200 205Ser Ile Lys Pro Leu Asp Leu Tyr Ala Leu Ser Ala Ile Lys Phe Glu

210 215 220Pro Ile Ser Val Glu Arg Tyr Thr Leu Trp Arg Tyr Lys Asp Leu Leu225 230 235 240Leu Glu Asn Pro Lys Leu Gly Val Val Leu Asn Ala Ser Asn Glu Val

245 250 255Ala Met Lys Lys Phe Leu Asn Gln Glu Ile Ala Phe Gly Gly Phe Ile

260 265 270Gln Ile Ile Ser Gln Ala Leu Glu Leu Tyr Ala Lys Lys Ser Phe Lys

275 280 285Leu Ser Ser Leu Asp Glu Val Leu Ala Leu Asp Lys Glu Val Arg Glu

290295300 Arg Phe Gly Ser Val Ala Arg Val 305310 (2) information SEQ ID NO:839

Sequence properties:

(A) length: 290 amino acid residue

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...290

(xi) sequence representation: SEQ ID NO:839: Met Leu Glu Asn Val Lys Lys Ser Leu Phe Arg Val Leu Cys Leu Gly 151015 Ala Leu Cys Leu Gly Gly Leu Met Ala Glu Gln Asp Pro Lys Glu Leu

20 25 30Val Gly Leu Gly Ala Lys Ser Tyr Lys Glu Gln Asp Phe Thr Gln Ala

35 40 45Lys Lys Tyr Phe Glu Lys Ala Cys Asp Leu Lys Glu Asn Ser Gly Cys

50 55 60Phe Asn Leu Gly Val Leu Tyr Tyr Gln Gly His Gly Val Glu Lys Asn65 70 75 80Leu Lys Lys Ala Ala Ser Phe Tyr Ser Lys Ala Cys Asp Leu Asn Tyr

85 90 95Ser Asn GlyCys His Leu Leu Gly Asn Leu Tyr Tyr Ser Gly Gln Gly

100 105 110Val Ser Gln Asn Thr Asn Lys Ala Leu Gln Tyr Tyr Ser Lys Ala Cys

115 120 125Asp Leu Lys Tyr Ala Glu Gly Cys Ala Ser Leu Gly Gly Ile Tyr His

130 135 140 Asp Gly Lys Val Val Thr Arg Asp Phe Lys Lys Ala Val Glu Tyr Phe145 150 155 160Thr Lys Ala Cys Asp Leu Asn Asp Gly Asp Gly Cys Thr Ile Leu Gly

165 170 175Ser Leu Tyr Asp Ala Gly Arg Gly Thr Pro Lys Asp Leu Lys Lys Ala

180 185 190Leu Ala Ser Tyr Asp Lys Ala Cys Asp Leu Lys Asp Ser Pro Gly Cys

195 200 205Phe Asn Ala Gly Asn Met Tyr His His Gly Glu Gly Ala Ala Lys Asn

210 215 220Phe Lys Glu Ala Leu Ala Arg Tyr Ser Lys Ala Cys Glu Leu Glu Asn225 230 235 240Gly Gly Gly Cys Phe Asn Leu Gly Ala Met Gln Tyr Asn Gly Glu Gly

245 250 255Ala Thr Arg Asn Glu Lys Gln Ala Ile Glu Asn Phe Lys Lys Gly Cys

260 265 270Lys Leu Gly Ala Lys Gly Ala Cys Asp Ile Leu Lys Gln Leu Lys Ile

275 280 285Lys Val

290(2) SEQ ID NO 840 information

Sequence properties:

(A) length: 237 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...237

(xi) sequence representation: 840: Met Lys Ser Asn Lys Lys Ser Asn His Leu Arg Ala Ile Tyr Arg Ala 151015 Leu Val Ile Ala Ile Gly Leu Ala Val Ile Ile Val Phe Asn Tyr Phe SEQ ID NO

20 25 30Asn Arg Lys Asn Asn Asn Ala Arg Ser Ser Arg Arg Ala Cys Ser Cys

35 40 45Phe Phe Ser Leu Thr Gly Val Asn Leu Glu Lys Ile Gly Ser Phe Asp

50 55 60Thr Gly Ala Lys Leu Ile Val Leu Asn His Gln Ser Leu Leu Asp Ile65 70 75 80Ile Tyr Leu Glu Ala Tyr His Pro Ser Asn Ile Cys Trp Ile Ala Lys

85 90 95Lys Glu Leu Gly Glu Ile Pro Phe Tyr Gly His Ala Leu Thr Asp Thr

100 105 110Gly Met Ile Leu Ile Asp Arg Glu Asp Lys Lys Gly Ile Val Set Leu

115 120 125Leu Lys Ala Cys Lys Glu Lys Leu Asp Gln Asn Arg Pro Leu Val Ile

130 135 140Phe Pro Glu Gly Thr Arg Gly Lys Gly Gly Glu Lys Phe Leu Pro Phe145 150 155 160Lys Gln Gly Ala Lys Ile Ile Ala Glu Lys Phe GlnLeu Lys Ile Gln

165 170 175Pro Met Val Leu Ile Asn Ser Ile Lys Ile Phe Asn Ser Lys Pro Leu

180 185 190Glu Ala Tyr Lys Ala Arg Thr Arg Leu Val Met Leu Glu Ser Tyr Thr

195 200 205Pro Asp Phe Ser Ser Pro Thr Trp Tyr Glu Glu Leu Gln Glu Arg Met

210215220 Gln Lys Glu Tyr Leu Lys His Tyr His Glu Leu Asn Ala 225230235 (2) SEQ ID NO:841 information

Sequence properties:

(A) length: 681 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...681

(xi) sequence representation: SEQ ID NO 841Met Gly Phe Glu Lys Ser Ile Leu Asp Asn Leu Asn Gly Ala Gln Lys 151015 Ile Ala Ala Cys His Ile Gln Gly Pro Leu Leu Ile Leu Ala Gly Ala

20 25 30Gly Ser Gly Lys Thr Lys Thr Leu Thr Ser Arg Leu Ala Tyr Leu Ile

35 40 45Gly Ala CysGly Val Pro Ser Glu Asn Thr Leu Thr Leu Thr Phe Thr

50 55 60Asn Lys Ala Ser Lys Glu Met Gln Glu Arg Ala Leu Lys Leu Leu Lys65 70 75 80Asn Gln Ala Leu Ile Pro Pro Leu Leu Cys Thr Phe His Arg Phe Gly

85 90 95Leu Leu Phe Leu Arg Gln His Met Asn Leu Leu Lys Arg Ala Cys Asp

100 105 110Phe Ser Val Leu Asp Ser Asp Glu Val Lys Thr Leu Cys Lys Gln Leu

115 120 125Lys Ile Ser Asn Phe Arg Ala Ser Ile Ser Gln Ile Lys Asn Gly Met

130 135 140Met Asp Leu Ser Val Gln Asp Ser Glu Cys Tyr Lys Ala Tyr Glu Leu145 150 155 160Tyr Gln Asn Ala Leu Lys Lys Asp Asn Leu Val Asp Phe Asp Asp Leu

165 170 175Leu Cys Leu Ser Leu Lys Ile Leu Gln Asp Asn Glu Lys Leu Ala Lys

18C 185 190Glu Thr Ser Glu Arg Tyr His Tyr Ile Met Val Asp Glu Tyr Gln Asp

195 200 205Thr Asn Ala Leu Gln Leu Glu Phe Leu Lys Gln Leu Ser Phe Thr His

210 215 220His Asn Leu Cys Val Val Gly Asp Asp Asp Gln Ser Ile Tyr Gly Phe225 230 235 240Arg Gly Ala Asp Ile Ser Asn Ile Leu Asn Phe Ser Lys His Phe Lys

245 250 255Gly Ala Lys Ile Val Lys Leu Glu Thr Asn Tyr Arg Ser Ser Ala Glu

260 265 270Ile Leu Ala Cys Ala Asn Ser Leu Ile Ser His Asn Gln His Arg His

275 280 285Ile Lys Thr Leu Gln Ser Phe Lys Gly Ser His Lys Ser Val Ile Cys

290 295 300Lys Glu Tyr Pro Thr Gln Lys Glu Glu Ser Leu Asp Val Ala Tyr Gln305 310 315 320Ile Lys Ala Leu Leu Lys Lys Gly Glu Asn Leu Glu Asn Ile Ala Ile

325 330 335Leu Tyr Arg Leu Asn Gly Leu Ser Arg Ser Ile Glu Glu Ser Leu Asn

340 345 350Ala Leu Asn Ile Pro Tyr Arg Leu Ile Gly Ala Val Ser Phe Tyr Glu

355 360 365Arg Ala Glu Val Lys Asp Ala Leu Ala Leu Met His Val Val Ala Lys

370 375 380Lys Asp Asp Arg Phe Phe Ile Lys Arg Val Leu Asn Lys Pro Pro Arg385 390 395 400Gly Leu Gly Lys Ile Thr Gln Glu Trp Ile Phe Ser Leu Leu Asp Glu

405 410 415Glu Gly Leu Asn Leu Glu Glu Ala Leu Lys Ile Gly Ala Phe Lys Asp

420 425 430Lys Leu Asn Pro Lys Asn Glu Tyr Ala Leu Lys Lys Phe Thr Ala Met

435 440 445Ile Gly Arg Leu Arg Glu Ala Phe Glu Ile Ser Val Glu Lys Phe Cys

450 455 460Glu Arg Phe Leu Glu Glu Thr Asn Leu Leu Lys Ser Tyr Glu Lys Glu465 470 475 480Asp Asn Tyr Glu Glu Arg Glu Gly Phe Val Lys Glu Leu Leu Ser Leu

485 490 495Val Lys Glu His Phe Lys Thr Asn Pro Thr His Ser Leu Leu Asp Phe

500 505 510Leu Asn Glu Ser Ala Leu Asp Val His Asn Thr Glu Asn Ala Gln Lys

515 520 525Val Ser Cys Met Ser Val His Met Ser Lys Gly Leu Glu Phe Lys His

530 535 540Val Phe Val Ile Gly Leu Glu Glu Gly Phe Phe Pro His Arg Gly Phe545 550 555 560Asn Gln Glu Ser Asp Leu Glu Glu Glu Arg Arg Leu Ala Tyr Val Ala

565 570 575Ile Thr Arg Ala Lys Glu Glu Leu Gln Leu Ser Tyr Val Lys Glu Arg

580 585 590Ser Tyr Phe Gly Arg Lys Ile Ser Cys Ser Pro Ser Val Phe Leu Glu

595 600 605Glu Ala Gln Leu Leu Gln Gln Asp Lys Pro Pro Lys Gln Ash His Gln

610 615 620Lys Asp Thr Pro Ile Lys Val Gly Asp Leu Ile Lys His Lys Ile Phe625 630 635 640Gly Thr Gly Arg Val Leu Gly Val Glu Lys Gly Leu Ser Gly Leu Cys

645 650 655Leu Lys Ile Asn Cys Gly Gly Asn Val Tyr Asp Lys Ile Ser Glu Lys

660 665 670Phe Val Glu Lys Val Asp Asn Glu Phe

675680 (2) information SEQ ID NO:842

Sequence properties:

(A) length: 276 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix)feature:

(A) name/keyword: misc _ feature

(B) Position: 1...276

(xi) sequence representation: 842: Met Lys Thr Ser Asn Thr Lys Thr Pro Lys Pro Val Leu Ile Ala Gly 151015 Pro Cys Val Ile Glu Ser Leu Glu Asn Leu Arg Ser Ile Ala Ile Lys SEQ ID NO

20 25 30Leu Gln Pro Leu Ala Asn Asn Glu Arg Leu Asp Phe Tyr Phe Lys Ala

35 40 45Ser Phe Asp Lys Ala Asn Arg Thr Ser Leu Glu Ser Tyr Arg Gly Pro

50 55 60Gly Leu Glu Lys Gly Leu Glu Met Leu Gln Thr Ile Lys Asp Glu Phe65 70 75 80Gly Tyr Lys Ile Leu Thr Asp Val His Glu Ser Tyr Gln Ala Ser Val

85 90 95Ala Ala Lys Val Ala Asp Ile Leu Gln Ile Pro Ala Phe Leu Cys Arg

100 105 110Gln Thr Asp Leu Ile Val Glu Val Ser Gln Thr Asn Ala Ile Val Asn

115 120 125Ile Lys Lys Gly Gln Phe Met Asn Pro Lys Asp Met Gln Tyr Ser Val

130 135 140Leu Lys Ala Leu Lys Thr Arg Asp Ser Ser Ile Gln Ser Pro Thr Tyr145 150 155 160Glu Thr Ala Leu Lys Asn Gly Val Trp Leu Cys Glu Arg Gly Ser Ser

165 170 175Phe Gly Tyr Gly Asn Leu Val Val Asp Met Arg Ser Leu Lys Ile Met

180 185 190Arg Glu Phe Ala Pro Val Ile Phe Asp Ala Thr His Ser Val Gln Met

195200 205Pro Gly Gly Ala Ash Gly Lys Ser Ser Gly Asp Ser Ser Phe Pro Pro

210 215 220Ile Leu Pro Arg Ala Ala Ala Ala Val Gly Ile Asp Gly Leu Phe Ala225 230 235 240Glu Thr His Ile Asp Pro Lys Asn Ala Leu Ser Asp Gly Ala Asn Met

245 250 255Leu Lys Pro Asp Glu Leu Glu His Leu Val Thr Asp Met Leu Lys Ile

260 265 270Gln Asn Leu Phe

275(2) SEQ ID NO 843 information

Sequence properties:

(A) length: 436 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...436

(xi) sequence representation: SEQ ID NO 843: Met Met Lys Phe Phe Leu Leu Lys Lys Phe Set Glu Phe Leu Asn Thr 151015 Gln Thr His Phe Asn Leu Lys Arg Leu Asn Ala Ser Ser Phe Leu Leu

20 25 30Glu Thr Phe Ser Lys Glu Lys His Ala Phe Val Val Asp Leu Ser Ala

35 40 45Pro Tyr Ile Gly Leu Ser Lys Lys Pro Pro Glu Ser Val Leu Lys Asn

50 55 60Thr Leu Ala Leu Asp Phe CysLeu Asn Lys Phe Thr Lys Asn Ala Lys65 70 75 80Ile Leu Gln Ala Asn Val Ile Asp Asn Asp Arg Ile Leu Glu Ile Lys

85 90 95Gly Ala Lys Asp Leu Ala Tyr Lys Ser Glu Thr Phe Ile Leu Arg Leu

100 105 110Glu Met Ile Pro Lys Lys Ala Asn Leu Met Ile Leu Asp Gln Glu Lys

115 120 125Cys Val Ile Glu Ala Phe Arg Phe Asn Asp Arg Val Ala Lys Asn Asp

130 135 140Ile Leu Gly Ala Leu Pro Pro Asn Ile Tyr Glu His Gln Glu Glu Asp145 150 155 160Leu Asp Phe Lys Gly Leu Leu Asp Ile Leu Glu Lys Asp Phe Leu Ser

165 170 175Tyr Gln His Lys Glu Leu Glu His Lys Lys Asn Gln Ile Ile Lys Arg

180 185 190Leu Asn Ala Gln Lys Glu Arg Leu Lys Glu Lys Leu Glu Lys Leu Glu

195 200 205Asp Pro Lys Thr Leu Gln Leu Glu Ala Lys Glu Leu Gln Thr Gln Ala

210 215 220Ser Leu Leu Leu Thr Tyr Gln His Leu Ile Asn Arg Arg Glu Asn Arg225 230 235 240Val Ile Leu Lys Asp Phe Glu Asp Lys Glu Cys Met Ile Glu Ile Asp

245 250 255Lys Ser Met Pro Leu Asn Ala Phe Ile Asn Lys Lys Phe Thr Leu Ser

260 265 270Lys Lys Lys Lys Gln Lys Ser Gln Phe Leu Tyr Leu Glu Glu Glu Asn

275 280 285Leu Lys Glu Lys Ile Ala Phe Lys Glu Asn Gln IleAsn Tyr Val Arg

290 295 300Asp Ala Ala Glu Glu Ser Val Leu Glu Met Phe Met Pro Val Lys Asn305 310 315 320Ser Lys Ile Lys Arg Pro Met Asn Gly Tyr Glu Val Leu Tyr Tyr Lys

325 330 335Asp Phe Lys Ile Gly Leu Gly Lys Asn Gln Lys Glu Asn Ile Lys Leu

340 345 350Leu Gln Asp Ala Arg Ala Asn Asp Leu Trp Met His Val Arg Asp Ile

355 360 365Pro Gly Ser His Leu Ile Val Phe Cys Gln Lys Asn Thr Pro Lys Asp

370 375 380Glu Val Ile Met Glu Leu Ala Lys Met Leu Ile Lys Met Gln Lys Asp385 390 395 400Ala Phe Asn Gly Tyr Glu Ile Asp Tyr Thr Gln Arg Lys Phe Val Lys

405 410 415Ile Ile Lys Gly Ala His Val Ile Tyr Ser Lys Tyr Arg Thr Ile Ser

420 425 430Leu Lys Asp Thr

435(2) information of SEQ ID NO:844

Sequence properties:

(A) length: 231 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...231

(xi) sequence representation: SEQ ID NO 844 Met Phe Lys Lys Ile Ile Phe Leu Cys Val Phe Leu Ile Gly Gly Phe 151015 Val Ile Pro Pro Leu Glu Ala Met Pro Ile Leu Arg Asn Lys Thr Pro

20 25 30Lys Lys Asn Tyr Gln Glu Ala His Glu Lys Leu Tyr Arg Ser Ile Ile

35 40 45Ash Arg Gln Lys Leu Thr Arg Lys Lys Ser Gly Trp Tyr Phe Leu Gly

50 55 60Gly Val Gly Ala Val Glu Ala Ile Lys Asp Tyr Gln Gly Lys Glu Met65 70 75 80Lys Asp Trp Ile Ala Thr Leu Asn Leu Lys Thr Gly Val Gln Ser Phe

85 90 95Phe Lys Lys Tyr Ile Gly Ile Arg Gly Val Phe Ala Trp Asp Leu Gly

100 105 110Ser Gly Lys Val Asn Tyr Gln Ser Tyr Lys Asp Pro Thr Asn Ser Phe

115 120 125Phe Thr Met Leu Ala Val Gly Leu Asp Val Ile Met Glu Phe Pro Leu

130 135 140Gly Ser Tyr Lys His Tyr Leu Gly Ala Phe Gly Gly Ala Arg Gly Ala145 150 155 160Leu Val Val Tyr Thr Asp Lys Gln Asn Phe Lys Phe Phe Lys His Ser

165 170 175Val Val Ser Gly Gly Leu Ala Ile Ser Gly Gly Val Met Leu Thr Leu

180 185 190Phe Leu Arg His Arg Ile Glu Leu Gly Phe Lys Ile Leu Pro Thr Ala

195 200 205Arg Leu Leu Ser Ser Ser Ser Arg Phe Glu Thr Ser Pro Leu Phe Tyr

210215220 Ala Ala Tyr Ser Tyr Lys Phe 225230 (2) SEQ ID NO:845 message

Sequence properties:

(A) length: 660 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...660

(xi) sequence representation: SEQ ID NO 845: Met Leu Lys Lys Ile Phe Tyr Gly Phe Ile Val Leu Phe Leu Ile Ile 151015 Val Gly Leu Leu Ala Val Leu Val Ala Gln Val Trp Val Thr Thr Asp

20 25 30Lys Asp Ile Ala Lys Ile Lys Asp Tyr Arg Pro Ser Val Ala Set Gln

35 40 45Ile Leu Asp Arg Lys Gly Arg Leu Ile Ala Asn Ile Tyr Asp Lys Glu

50 55 60Phe Arg Phe Tyr Ala Arg Phe Glu Glu Ile Pro Pro Arg Phe Val Glu65 70 75 80Ser Leu Leu Ala Val Glu Asp Thr Leu Phe Phe Glu His Gly Gly Ile

85 90 95Asn Leu Asp Ala Val Met Arg Ala Met Ile Lys Asn Ala Lys Ser Gly

100 105 110Arg Tyr Thr Glu Gly Gly Ser Thr Leu Thr Gln Gln Leu Val Lys Asn115 120 125Met Val Leu Thr Arg Glu Lys Thr Leu Thr Arg Lys Leu Lys Glu Ala

130 135 140Ile Ile Ser Ile Arg Ile Glu Lys Val Leu Ser Lys Glu Glu Ile Leu145 150 155 160Glu Arg Tyr Leu Asn Gln Thr Phe Phe Gly His Gly Tyr Tyr Gly Val

165 170 175Lys Thr Ala Ser Leu Gly Tyr Phe Lys Lys Pro Leu Asp Lys Leu Thr

180 185 190Leu Lys Glu Ile Thr Met Leu Val Ala Leu Pro Arg Ala Pro Set Phe

195 200 205Tyr Asp Pro Thr Lys Asn Leu Glu Phe Ser Leu Ser Arg Ala Asn Asp

210 215 220Ile Leu Arg Arg Leu Tyr Ser Leu Gly Trp Ile Ser Ser Asn Glu Leu225 230 235 240Lys Ser Ala Leu Asn Glu Val Pro Ile Val Tyr Asn Gln Thr Ser Thr

245 250 255Gln Asn Ile Ala Pro Tyr Val Val Asp Glu Val Leu Lys Gln Leu Asp

260 265 270Gln Leu Asp Gly Leu Lys Thr Gln Gly Tyr Thr Ile Lys Leu Thr Ile

275 280 285Asp Leu Asp Tyr Gln Arg Leu Ala Leu Glu Ser Leu Arg Phe Gly His

290 295 300Gln Lys Ile Leu Glu Lys Ile Ala Lys Glu Lys Pro Lys Thr Asn Ala305 310 315 320Ser Asn Asp Lys Asp Glu Asp Asn Leu Asn Ala Ser Met Ile Val Thr

325 330 335Glu Thr Ser Thr Gly Lys Ile Leu Ala Leu Val Gly Gly Ile Asp Tyr

340 345 350Lys Lys Ser Ala Phe Asn Arg Ala Thr Gln Ala Lys Arg Gln Phe Gly

355360 365Ser Ala Ile Lys Pro Phe Val Tyr Gln Ile Ala Phe Asp Asn Gly Tyr

370 375 380Ser Thr Thr Ser Lys Ile Pro Asp Thr Ala Arg Asn Phe Glu Asn Gly385 390 395 400Asn Tyr Ser Lys Asn Ser Val Gln Asn His Ala Trp His Pro Ser Asn

405 410 415Tyr Thr Arg Lys Phe Leu Gly Leu Val Thr Leu Gln Glu Ala Leu Ser

420 425 430His Ser Leu Asn Leu Ala Thr Ile Asn Leu Ser Asp Gln Leu Gly Phe

435 440 445Glu Lys Ile Tyr Gln Ser Leu Ser Asp Met Gly Phe Lys Asn Leu Pro

450 455 460Lys Asp Leu Ser Ile Val Leu Gly Ser Phe Ala Ile Ser Pro Ile Asp465 470 475 480Ala Ala Glu Lys Tyr Ser Leu Phe Ser Asn Tyr Gly Thr Met Leu Lys

485 490 495Pro Met Leu Ile Glu Ser Ile Thr Asn Gln Gln Asn Glu Val Lys Thr

500 505 510Phe Thr Pro Ile Glu Thr Lys Lys Ile Thr Ser Lys Glu Gln Ala Phe

515 520 525Leu Thr Leu Ser Ala Leu Met Asp Ala Val Glu Asn Gly Thr Gly Ser

530 535 540Leu Ala Arg Ile Lys Gly Leu Glu Ile Ala Gly Lys Thr Gly Thr Ser545 550 555 560Asn Asn Asn Ile Asp Ala Trp Phe Ile Gly Phe Thr Pro Thr Leu Gln

565 570 575Ser Val Ile Trp Phe Gly Arg Asp Asp Asn Thr Pro Ile Gly Lys Gly

580585 590Ala Thr Gly Gly Val Val Ser Ala Pro Val Tyr Ser Tyr Phe Met Arg

595 600 605Asn Ile Leu Ala Ile Glu Pro Ser Leu Lys ArG Lys Phe Asp Val Pro

610 615 620Lys Gly Leu Arg Lys Glu Ile Val Asp Lys Ile Pro Tyr Tyr Ser Ser625 630 635 640Pro Asn Ser Ile Thr Pro Thr Pro Lys Lys Thr Asp Asp Ser Glu Glu

645 650 655Arg Leu Leu Phe

660(2) SEQ ID NO:846 information

Sequence properties:

(A) length: 324 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...324

(xi) sequence representation: SEQ ID NO:846: Met Lys Tyr Leu Trp Leu Phe Leu Ile Tyr Ala Ile Gly Leu Phe Ala 151015 Thr Asp Lys Thr Leu Asp Ile Ile Lys Thr Ile Gln Lys Leu Pro Lys

20 25 30Ile Glu Val Arg Tyr Ser Ile Asp Asn Asp Ala Asn Tyr Ala Leu Lys

35 40 45Leu His Glu Val Leu Ala Asn Asp Leu Lys Thr Ser Gln His Phe Asp

50 55 60Val Ser Gln Asn Lys Glu Gln Gly Ala Ile Asn Tyr AlaGlu Leu Lys65 70 75 80Asp Lys Lys Val His Leu Val Ala Leu Val Ser Val Ala Val Glu Asn

85 90 95Gly Asn Lys Ile Ser Arg Leu Lys Leu Tyr Asp Val Asp Thr Gly Thr

100 105 110Leu Lys Lys Thr Phe Asp Tyr Pro Ile Val Ser Leu Asp Leu Tyr Pro

115 120 125Phe Ala Ala His Asn Met Ala Ile Val Val Asn Asp Tyr Leu Lys Ala 130 135 140Pro Ser Ile Ala Trp Met Lys Arg Leu Ile Val Phe Ser Lys Tyr Ile145 150 155 160Gly Pro Gly Ile Thr Asn Ile Ala Leu Ala Asp Tyr Thr Met Arg Tyr

165 170 175Gln Lys Glu Ile Ile Lys Asn Asn Arg Leu Asn Ile Phe Pro Lys Trp

180 185 190Ala Asn Ala Glu Gln Thr Glu Phe Tyr Tyr Thr Gln Tyr Gly Glu Lys

195 200 205Thr Pro Met Ile Leu Lys Tyr Asn Ile Gln Lys Ala Thr His Glu Asn

210 215 220Ile Ala Ser Ser Gln Gly Met Ala Val Val Ser Ser Val Ser Ser Asp225 230 235 240Gly Ser Lys Ile Leu Met Ser Leu Ala Pro Asp Gly Gln Pro Asp Val

245 250 255Tyr Leu Tyr Asp Thr His Lys Lys Thr Lys Thr Lys Ile Thr Arg Tyr

260 265 270Pro Gly Ile Asp Val Ser Gly Val Phe Leu Glu Asp Asp Lys Ser Met

275 280 285Ala Phe Val Ser Asp Arg Ser Gly Tyr Pro Asn Ile Tyr Met Lys Lys

290295300 Leu Gly Leu Lys Glu Ser Ala Glu Gln Leu Leu Tyr Glu Gly Arg Ser 305310315320 Asn Glu Ser Ile (2) SEQ ID NO:847 information

Sequence properties:

(A) length: 1288 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1288

(xi) sequence representation: SEQ ID NO 847: Met Glu Ile Gln Gln Thr His Arg Lys Ile Asn Arg Pro Leu Val Ser 151015 Leu Val Leu Ala Gly Ala Leu Ile Ser Ala Ile Pro Gln Glu Ser His

20 25 30Ala Ala Phe Phe Thr Thr Val Ile Ile Pro Ala Ile Val Gly Gly Ile

35 40 45Ala Thr Gly Thr Ala Val Gly Thr Val Ser Gly Leu Leu Ser Trp Gly

50 55 60Leu Lys Gln Ala Glu Glu Ala Asn Lys Thr Pro Asp Lys Pro Asp Lys65 70 75 80Val Trp Arg lle Gln Ala Gly Lys Gly Phe Asn Glu Phe Pro Asn Lys

85 90 95Glu Tyr Asp Leu Tyr Lys Ser Leu Leu Ser Ser Lys Ile Asp Gly Gly

100 105 110Trp Asp Trp Gly Asn Ala Ala Arg His Tyr Trp Val Lys Gly Gly Gln

115 120 125Trp Asn Lys Leu Glu Val Asp Met Lys Asp Ala Val Gly Thr Tyr Lys

130 135 140Leu Ser Gly Leu Arg Asn Phe Thr Gly Gly Asp Leu Asp Val Asn Met 145 150 155 160Gln Lys Ala Thr Leu Arg Leu Gly Gln Phe Asn Gly Asn Ser Phe Thr

165 170 175Ser Tyr Lys Asp Ser Ala Asp Arg Thr Thr Arg Val Asn Phe Asn Ala

180 185 190Lys Asn Ile Ser Ile Asp Asn Phe Val Glu Ile Asn Asn Arg Val Gly

195 200 205Ser Gly Ala Gly Arg Lys Ala Ser Ser Thr Val Leu Thr Leu Gln Ala

210 215 220Ser Glu Gly Ile Thr Ser Ser Lys Asn Ala Glu Ile Ser Leu Tyr Asp225 230 235 240Gly Ala Thr Leu Asn Leu Ala Ser Asn Ser Val Lys Leu Asn Gly Asn

245 250 255Val Trp Met Gly Arg Leu Gln Tyr Val Gly Ala Tyr Leu Ala Pro Ser

260 265 270Tyr Ser Thr Ile Asn Thr Ser Lys Val Gln Gly Glu Val Asp Phe Asn

275 280 285His Leu Thr Val Gly Asp Gln ASn Ala Ala Gln Ala Gly Ile Ile Ala

290 295 300Ser Asn Lys Thr His Ile Gly Thr Leu Asp Leu Trp Gln Ser Ala Gly305 310 315 320Leu Asn Ile Ile Ala Pro Pro Glu Gly Gly Tyr Lys Asp Lys Pro Asn

325 330 335Ser Thr Thr Ser Gln Ser Gly Thr Lys Asn Asp Lys Lys Glu Ile Ser

340 345350Gln Asn Asn Asn Ser Asn Thr Glu Val Ile Asn Pro Pro Asn Asn Thr

355 360 365Gln Lys Thr Glu Thr Glu Pro Thr Gln Val Ile Asp Gly Pro Phe Ala

370 375 380Gly Gly Lys Asp Thr Val Val Asn Ile Phe His Leu Asn Thr Lys Ala385 390 395 400Asp Gly Thr Ile Lys Val Gly Gly Phe Lys Ala Ser Leu Thr Thr Asn

405 410 415Ala Ala His Leu Asn Ile Gly Lys Gly Gly Val Asn Leu Ser Asn Gln

420 425 430Ala Ser Gly Arg Thr Leu Leu Val Glu Asn Leu Thr Gly Asn Ile Thr

435 440 445Val Asp Gly Pro Leu Arg Val Asn Asn Gln Val Gly Gly Tyr Ala Leu

450 455 460Ala Gly Ser Ser Ala Asn Phe Glu Phe Lys Ala Gly Val Asp Thr Lys465 470 475 480Asn Gly Thr Ala Thr Phe Asn Asn Asp Ile Ser Leu Gly Arg Phe Val

485 490 495Asn Leu Lys Val Asp Ala His Thr Ala Asn Phe Lys Gly Ile Asp Thr

500 505 510Gly Asn Gly Gly Phe Asn Thr Leu Asp Phe Ser Gly Val Thr Asp Lys

515 520 525Val Asn Ile Asn Lys Leu Ile Thr Ala Ser Thr Asn Val Ala Val Lys

530 535 540Asn Phe Asn Ile Asn Glu Leu Ile Val Lys Thr Asn Gly Ile Ser Val545 550 555 560Gly Glu Tyr Thr His Phe Ser Glu Asp Ile Gly Ser Gln Ser Arg Ile

565 570 575Asn Thr Val Arg Leu Glu Thr Gly Thr Arg Sel Ile Phe Ser Gly Gly

580 585 590Val Lys Phe Lys Ser Gly Glu Lys Leu Val Ile Asn Asp Phe Tyr Tyr595 600 605Ser Pro Trp Asn Tyr Phe Asp Ala Arg Asn Val Lys Asn Val Glu Ile

610 615 620Thr Arg Lys Phe Ala Ser Ser Thr Pro Glu Asn Pro Trp Gly Thr Ser625 630 635 640Lys Leu Met Phe Asn Asn Leu Thr Leu Gly Gln Asn Ala Val Met Asp

645 650 655Tyr Ser Gln Phe Ser Asn Leu Thr Ile Gln Gly Asp Phe Ile Asn Asn

660 665 670Gln Gly Thr Ile Asn Tyr Leu Val Arg Gly Gly Lys Val Ala Thr Leu

675 680 685Asn Val Gly Asn Ala Ala Ala Met Met Phe Asn Asn Asp Ile Asp Ser

690 695 700Ala Thr Gly Phe Tyr Lys Pro Leu Ile Lys Ile Asn Ser Ala Gln Asp705 710 715 720Leu Ile Lys Asn Thr Glu His Val Leu Leu Lys Ala Lys Ile Ile Gly

725 730 735Tyr Gly Asn Val Ser Thr Gly Thr Asn Gly Ile Ser Asn Val Asn Leu

740 745 750Glu Glu Gln Phe Lys Glu Arg Leu Ala Leu Tyr Asn Asn Asn Asn Arg

755 760 765Met Asp Thr Cys Val Val Arg Asn Thr Asp Asp Ile Lys Ala Cys Gly

770 775 780Met Ala Ile Gly Asn Gln Ser Met Val Asn Asn Pro Asp Asn Tyr Lys785 790 795 800Tyr Leu Ile Gly Lys Ala Trp Arg Asn Ile GlyIle Ser Lys Thr Ala

805 810 815Asn Gly Ser Lys Ile Ser Val Tyr Tyr Leu Gly Asn Ser Thr Pro Thr

820 825 830Glu Asn Gly Gly Asn Thr Thr Asn Leu Pro Thr Asn Thr Thr Asn Asn

835 840 845Ala His Ser Ala Asn Tyr Ala Leu Val Lys Asn Ala Pro Phe Ala His

850 855 860Ser Ala Thr Pro Asn Leu Val Ala Ile Asn Gln His Asp Phe Gly Thr865 870 875 880Ile Glu Ser Val Phe Glu Leu Ala Asn Arg Ser Lys Asp Ile Asp Thr

885 890 895Leu Tyr Thr His Ser Gly Ala Gln Gly Arg Asp Leu Leu Gln Thr Leu

900 905 910Leu Ile Asp Ser His Asp Ala Gly Tyr Ala Arg Gln Met Ile Asp Asn

915 920 925Thr Ser Thr Gly Glu Ile Thr Lys Gln Leu Asn Ala Ala Thr Asp Ala

930 935 940Leu Asn Asn Val Ala Ser Leu Glu His Lys Gln Ser Gly Leu Gln Thr945 950 955 960Leu Ser Leu Ser Asn Ala Met Ile Leu Asn Ser Arg Leu Val Asn Leu

965 970 975Ser Arg Lys His Thr Asn His Ile Asn Ser Phe Ala Gln Arg Leu Gln

980 985 990Ala Leu Lys Gly Gln Glu Phe Ala Ser Leu Glu Ser Ala Ala Glu Val

995 1000 1005Leu Tyr Gln Phe Ala Pro Lys Tyr Glu Lys Pro Thr Asn Val Trp Ala

1010 1015 1020Asn Ala Ile Gly Gly Ala Ser Leu Asn Ser GlySer Asn Ala Ser Leu1025 1030 1035 1040Tyr Gly Thr Ser Ala Gly Val Asp Ala Phe Leu Asn Gly Asn Val Glu

1045 1050 1055Ala Ile Val Gly Gly Phe Gly Ser Tyr Gly Tyr Ser Ser Phe Ser Asn

1050 1065 1070Gln Ala Asn Ser Leu Asn Ser Gly Ala Asn Asn Ala Asn Phe Gly Val

1075 1080 1085Tyr Ser Arg Phe Phe Ala Asn Gln His Glu Phe Asp Phe Glu Ala Gln

1090 1095 1100Gly Ala Leu Gly Ser Asp Gln Ser Ser Leu Asn Phe Lys Ser Thr Leu1105 1110 1115 1120Leu Gln Asp Leu Asn Gln Ser Tyr Asn Tyr Leu Ala Tyr Ser Ala Thr

1125 1130 1135Ala Arg Ala Ser Tyr Gly Tyr Asp Phe Ala Phe Phe Arg Asn Ala Leu

1140 1145 1150Val Leu Lys Pro Ser Val Gly Val Ser Tyr Asn His Leu Gly Ser Thr

1155 1160 1165Asn Phe Lys Ser Asn Ser Gln Sar Gln Val Ala Leu Lys Asn Gly Ala

1170 1175 1180Ser Ser Gln His Leu Phe Asn Ala Asn Ala Asn Val Glu Ala Arg Tyr1185 1190 1195 1200Tyr Tyr Gly Asp Thr Ser Tyr Phe Tyr Leu His Ala Gly Val Leu Gln

1205 1210 1215Glu Phe Ala His Phe Gly Ser Asn Asp Val Ala Ser Leu Asn Thr Phe

1220 1225 1230Lys Ile Asn Ala Ala Arg Ser Pro Leu Ser Thr Tyr Ala Arg Ala Met

1235 1240 1245Met Gly Gly Glu LeuGln Leu Ala Lys Glu Val Phe Leu Asn Leu Gly

1250 1255 1260Val Val Tyr Leu His Asn Leu Ile Ser Asn Ala Ser His Phe Ala Ser1265 1270 1275 1280Asn Leu Gly Met Arg Tyr Ser Phe

1285(2) SEQ ID NO:848 information

Sequence properties:

(A) length: 385 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...385

(xi) sequence representation: SEQ ID NO 848: Met Lys Asp Ser Phe Leu Phe Thr Ser Glu Ser Val Thr Glu Gly His 151015 Pro Asp Lys Met Ala Asp Gln Ile Ser Asp Ala Val Leu Asp Tyr Ile

20 25 30Ile Glu Arg Asp Lys Lys Ala Lys Val Ala Cys Glu Thr Leu Val Ser

35 40 45Asn Gly Phe Cys Met Ile Thr Gly Glu Leu Lys Thr Ser Val Tyr Ala

50 55 60Pro Met Gln Glu Ile Ala Arg Glu Val Val Lys Lys Ile Gly Tyr Thr65 70 75 80Asp Ala Leu Tyr Gly Phe Asp Tyr Arg Ser Ala Ala Val Leu Asn Gly

85 90 95Ile Gly Glu Gln Ser Pro Asp Ile Asn Gln Gly Val Asp Arg Glu Asp

100 105 110Gly Glu Ile Gly Ala Gly Asp Gln Gly Leu Met Phe Gly Tyr Ala Cys

115 120 125Lys Glu Thr Glu Thr Leu Met Pro Leu Pro Ile His Leu Ala His Gln

130 135 140Leu Ala Phe Ala Leu Ala Gln Lys Arg Lys Asp Asn Thr Leu Pro Phe145 150 155 160 Leu Arg Pro Asp Gly Lys Ser Gln Val Ser Val Arg Tyr Glu Asn Asn

165 170 175Lys Pro Val Ser Val Asp Thr Ile Val Ile Ser Thr Gln His Ser Pro

180 185 190Glu Val Ser Gln Lys His Leu Lys Glu Ala Val Ile Glu Glu Ile Val

195 200 205Tyr Lys Val Leu Pro Lys Glu Tyr Leu His Asp Asn Ile Lys Phe Phe

210 215 220Ile Asn Pro Thr Gly Lys Phe Val Ile Gly Gly Pro Gln Gly Asp Ala225 230 235 240Gly Leu Thr Gly Arg Lys Ile Ile Val Asp Thr Tyr Gly Gly Phe Cys

245 250 255Pro His Gly Gly Gly Ala Phe Ser Gly Lys Asp Pro Ser Lys Val Asp

260 265 270Arg Ser Ala Ala Tyr Ala Ala Arg Tyr Val Ala Lys Asn Leu Val Ala

275 280 285Ser Gly Val Cys Asp Lys Ala Thr Val Gln Leu Ala Tyr Ala Ile Gly

290 295 300Val Ile Glu Pro Val Ser Ile Tyr Val Asn Thr His Asn Thr Ser Lys305 310 315 320His Ser Ser Ala Glu Leu Glu Lys Cys Val Lys Ser Val Phe Lys Leu

325 330 335Thr Pro Lys Gly Ile Ile Glu Ser Leu Asp Leu Leu Arg Pro Ile Tyr

340 345 350Ser Leu Thr Ser Ala Tyr Gly His Phe Gly Arg Glu Leu Glu Glu Phe

355 360 365Thr Trp Glu Lys Thr Asn Lys Val Glu Glu Ile Lys Ala Phe Phe Lys

370375380 Arg385(2) SEQ ID NO:849 information

Sequence properties:

(A) length: 68 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...68

(xi) sequence representation: SEQ ID NO 849: Met Lys Phe Leu Asn Gly Leu Ala Gly Asn Leu Leu Ile Val Val Ile 151015 Leu Leu Cys Val Val Val Phe Phe Ala Leu Lys Ala Ile His Ile Gln

20 25 30Lys Glu Gln Ala Thr Asn Tyr Tyr Arg Tyr Lys Asp Ile Asn Ala Leu

35 40 45Glu Ala Lys Asn Thr Gln Asn His Ala Asn Tyr Glu Leu Val Asn Gln

505560 Gly Ser Lys Lys65(2) SEQ ID NO:850 information

Sequence properties:

(A) length: 502 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...502

(xi) sequence representation: SEQ ID NO 850: Leu Lys Ile Phe Leu Val Ile Leu Ser Val Phe Phe Phe Asn Gly Cys 151015 Phe Gly Leu Val Tyr Lys Thr Pro Ile Ser Asn Pro Pro Ile Ser Tyr

20 25 30Asp Pro Tyr Thr Thr Thr Ile Gly Ser Leu Tyr Ala Lys Asn Leu Lys

35 40 45Glu Asn Pro Lys His Ser Ala Ala Ile Leu Leu Glu Asp Gly Phe Asp

50 55 60Ala Leu Leu His Arg Val Gly Leu Ile Aru Met Ser Gln Lys Ser Ile65 70 75 80Asp Met Gln Thr Tyr Ile Tyr Lys Asn Asp Leu Ser Ser Gln Val Ile

85 90 95Ala Lys Glu Leu Leu Asn Ala Ala Asn Arg Gly Val Lys Val Arg Ile

l00 105 110Leu Leu Asp Asp Asn Gly Leu Asp Ser Asp Phe Ser Asp Ile Met Leu

115 120 125Leu Asn Phe His Lys Asn Ile Glu Val Lys Ile Phe Asn Pro Tyr Tyr

130 135 140Ile Arg Asn Lys Gly Leu Arg Tyr Phe Glu Met Leu Ala Asp Tyr Glu145 150 155 160Arg Ile Lys Lys Arg Me5 His Asn Lys Leu Phe Ile Val Asp Asn Phe

165 170 175Ala Val Ile Ile Gly Gly Arg Asn Ile Gly Asp Asn Tyr Phe Asp Asn

180 185 190Asp Leu Asp Thr Asn Phe Leu Asp Leu Asp Ala Leu Phe Phe Gly Gly

195 200 205Val Ala Ser Lys Ala Lys Glu Ser Phe Glu Asn Tyr Trp Arg Phe His

210 215 220Arg Ser Ile Pro Val Ser Leu Leu Arg Thr His Lys Arg Leu Lys Asn225 230 235 240Asn Val Lys Glu Ile Ala Lys Leu His Glu Lys Ile Pro Ile Ser Ala

245 250 255Glu Asp Ala Asn Glu Phe Glu Lys Lys Val Asn Asp Phe Ile Glu Arg

260 265 270Phe Gln Lys Tyr Gln Tyr Pro Ile Tyr Tyr Gly Asn Ala Ile Phe Leu

275 280 285Ala Asp Leu Pro Ala Lys Ile Asp Thr Pro Leu Tyr Ser Pro Ile Lys

290 295 300Ile Ala Phe Glu Lys Ala Leu Lys Asn Ala Lys Asp Ser Val Phe Ile305 310 315 320Ala Ser Ser Tyr Phe Ile Pro Gly Lys Lys Ile Met Lys Ile Phe Lys

325 330 335Asn Gln Ile Ser Lys Gly Ile Glu Leu Asn Ile Leu Thr Asn Ser Leu

340 345 350Ser Ser Thr Asp Ala Ile Val Val Tyr Gly Ala Trp Glu Arg Tyr Arg

355 360 365Asn Lys Leu Val Arg Met Gly Ala Asn Val Tyr Glu Ile Arg Asn Asp

370 375 380Phe Phe Asn Arg Gln Ile Lys Gly Arg Phe Ser Thr Lys His Ser Leu385390 395 400His Gly Lys Thr Ile Val Phe Asp Asp Ala Leu Thr Leu Leu Gly Ser

405 410 415Phe Asn Ile Asp Pro Arg Ser Ala Tyr Ile Asn Thr Glu Ser Ala Val

420 425 430Leu Phe Asp Asn Pro Ser Phe Ala Lys Arg Val Arg Leu Ser Leu Lys

435 440 445Asp His Ala Gln Gln Ser Trp His Leu Val Leu Tyr Arg His Arg Val

450 455 460Ile Trp Glu Ala Thr Glu Glu Gly Ile Leu Ile His Glu Lys Asn Ser465 470 475 480Pro Asp Thr Ser Phe Phe Leu Arg Leu Ile Lys Glu Trp Ser Lys Val

485 490 495Leu Pro Glu Arg Glu Leu

500(2) SEQ ID NO 851 information

Sequence properties:

(A) length: 177 amino acid residue

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...177

(xi) sequence representation: SEQ ID NO:851 Met Arg Phe Ser Tyr Ile Glu Pro Arg Ala Lys Tyr Leu Ile Ser Lys 151015 leu Ser Lys Ile Trp Val Phe Tyr Ile Phe Leu Ser Phe Val Leu Ile

2025 30Gly Gly Leu Val Trp Phe Met His Asn Ala Ile Lys Arg Ala Gln Asp

35 40 45Ala Ser Ser Leu Thr Ile Gln Glu Arg Leu Tyr Arg His Glu Ile

50 55 60Ser Arg Leu Gln Val Lys Thr Asp Glu Thr Leu Lys Leu Ile Lys Glu65 70 75 80Ala Lys Lys Arg Leu Asn Tyr Asn Asp Asp Ile Arg Asp Val Leu Gln

85 90 95Gly Leu Leu Asn Ile Val Pro Asp Leu Ile Thr Ile Asn Ser Ile Glu

100 105 110Ile Asp Gln Gln Ser Val Val Val Ser Gly Lys Thr Pro Ser Lys Glu

115 120 125Ala Phe Tyr Phe Leu Phe Gln Asn Lys Leu Asn Pro Met Phe Asp Tyr

130 135 140Ser Arg Ala Glu Phe Phe Pro Leu Ser Asp Gly Trp Phe Asn Phe Val145 150 155 160Ser Thr Asn Phe Ser Asn Ser Leu Leu Ile Lys Asn Pro Glu Ser Ile

165170175 Lys (2) SEQ ID NO:852 information

Sequence properties:

(A) length: 222 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...222

(xi) sequence representation: SEQ ID NO 852: Met Arg Lys Ile Leu Leu Met Gly Leu Ile Leu Gln Ala Leu Phe Gly 151015 Glu Glu Ala Ala Gln Glu Leu Leu Gln Cys Ser Ala Ile Phe Glu Ser

20 25 30Lys Lys Ala Glu Leu Lys Glu Asp Leu Arg Gln Leu Ser Glu Lys Glu

35 40 45Gln Ser Leu Arg Ile Leu Gln Thr Glu Asn Ala Arg Leu Leu Asp Glu

50 55 60Lys Ser Asp Leu Leu Asn Lys Lys Glu Lys Glu Ile Asp Glu Lys Leu65 70 75 80Lys Asn Leu Ala Ala Lys Glu Glu Ala Phe Lys Thr Leu Gln Thr Glu

85 90 95Glu Lys Lys Arg Leu Lys Asn Leu Ile Glu Glu Asn Glu Gly Ile Leu

100 105 110Arg Glu Ile Lys Gln Ala Lys Asp Ser Lys Ile Gly Glu Thr Tyr Ser

115 120 125Lys Met Lys Asp Ser Lys Ser Ala Leu Ile Leu Glu Asn Leu Pro Thr

130 135 140Gln Asn Ala Leu Glu Ile Leu Met Ala Leu Lys Pro Gln Glu Leu Gly145 150 155 160Lys Ile Leu Ala Lys Met Asp Pro Lys Lys Ala Ala Ala Leu Thr Glu

165 170 175Leu Trp Gln Lys Pro Pro Lys Glu Asn Lys Glu Asn Lys Glu Ser Gln

180 185 190Lys Thr Thr Asp Pro Thr Pro Pro Thr Pro Pro Thr Pro Pro Lys Glu

195 200 205Pro Thr Leu Lys Asp Pro Asn Val Lys Glu Pro Thr Gly Val

210215220 (2) information of SEQ ID NO 853

Sequence properties:

(A) length: 431 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...431

(xi) sequence representation: SEQ ID NO 853: Met Asn Ile Gln Thr Lys Lys Arg Phe Leu Ala Asn Leu Leu Leu Phe 151015 Ser Leu Phe Ser Cys Leu Lys Ala Glu Thr Leu Ser Glu Asp His Gln

20 25 30Ile Leu Leu Ser Ser Asp Ala Phe His Arg Gly Asp Phe Ala Thr Ala

35 40 45Gln Lys Gly Tyr Met Asn Leu Tyr Lys Gln Thr Asn Lys Val Val Tyr

50 55 60Ala Lys Glu Ala Ala Ile Ser Ala Ala Ser Leu Gly Asp Ile Lys Thr65 70 75 80Ala Met His Leu Ala Met Leu Tyr Gln Lys Ile Thr ASn Asn Arg Asn

85 90 95Asp Val Ser Ile Asn Lys Ile Leu Val Asp Gly Tyr Ala Gln Met GIy

100 105 110Gln Ile Asp Lys Ala Ile Glu Leu Leu His Lys Ile Arg Lys Glu Glu

115 120 125Lys Thr Ile Ala Thr Asp Asn Val Leu Gly Thr Leu Tyr Leu Thr Gln

130 135 140Lys Arg Leu Asp Lys Ala Phe Pro Leu Leu Asn Lys Phe Tyr Asn Gln145 150 155 160Val His Asp Glu Asp Ser Leu Glu Lys Leu Ile Thr Ile Tyr Phe Leu

165 170 175Gln Asn Arg Lys Lys Glu Gly Leu Asp Leu Leu Gln Ser His Ile Asp

180 185 190Arg Tyr Gly Cys Ser Glu Gln Leu Cys Gln Lys Ala Leu Asn Thr Phe

195 200 205Thr Gln Phe Asn Glu Leu Asp Leu Ala Lys Thr Thr Phe Ala Arg Leu

210 215 220Tyr Glu Lys Asn Pro Ile Val Gln Asn Ala Gln Phe Tyr Ile Gly Val225 230 235 240Leu Ile Leu Leu Lys Glu Phe Asp Lys Ala Gln Gln Ile Ala Glu Leu

245 250 255Phe Pro Phe Asp Arg Arg Leu Leu Leu Asp Leu Tyr Thr Ala Gln Lys

260 265 270Lys Phe Asp Gln Ala Ser Lys Gln Ala Ser Leu Ile Tyr Gln Glu Arg

275 280 285Lys Asp Pro Lys Phe Leu Gly Leu Glu Ala Ile Tyr His Tyr Glu Ser

290 295 300Leu Ser Ala Asn Lys Lys Lys Leu Thr Lys Glu Glu Met Leu Pro Ile305 310 315 320Ile Gln Lys Leu Glu Gln Ala Thr Lys Glu Arg Gln Ala Trp Leu Ala

325 330 335Lys Thr Lys Asp Lys Glu Asp Ala Gln Asp Ala Phe Phe Tyr Asn Phe

340 345 350Leu Gly Tyr Ser Leu Ile Asp Tyr Asp Met Asp Val Lys Arg Gly Met

355 360 365Asp LeuVal Arg Lys Ala Leu Ala Leu Asp Ser Asn Ser Val Leu Tyr

370 375 380Leu Asp Ser Leu Ala Trp Gly Tyr Tyr Lys Leu Gly Asn Cys Leu Glu385 390 395 400Ala Lys Lys Ile Phe Ser Ser Ile Ala Lys Glu Leu Ile Gln Asn Glu

405 410 415Pro Glu Leu Lys Glu His Asn Lys Ile Ile Gln Glu Cys Lys Lys

420425430 (2) information of SEQ ID NO 854

Sequence properties:

(A) length: 97 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...97

(xi) sequence representation: 854: Met Leu Tyr Ala Ser Lys Ala Arg Leu Phe Leu Gln Ile Lys Gly Lys15 l 015 Phe Met Leu Arg Ile Leu Ile Pro Leu Leu Ile Ile Val Trp Val Leu SEQ ID NO

20 25 30Trp Arg Leu Phe Leu Arg Gln Lys Pro His Lys Asp Asp His Arg Asp

35 40 45Asn His Ser Tyr Thr Gln Gln Thr Pro Lys Glu Leu Glu Asp His Met

50 55 60Ile Val Cys Ser Lys Cys Gln Thr Tyr Val Ser Ser Lys Asp Ala Ile65 70 75 80Tyr Ser Gly Ala Val Ala Tyr Cys Ser Glu Thr Cys Leu Lys Asp Lys

859095 Gly (2) SEQ ID NO:855 information

Sequence properties:

(A) length: 479 an amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...479

(xi) sequence representation: SEQ ID NO 855: Met Lys Asn Ser Ala Pro Leu Lys Asn Lys VaI Phe Cys Gly Leu Tyr 151015 Val Leu Ser Leu Ser Ala Ser Val Gln Ala Phe Asp Tyr Lys Ile Glu

20 25 30Val Leu Ala Glu Ser Phe Ser Lys Val Gly Phe Asn Lys Lys Lys Ile

35 40 45Asp Ile Ala Arg Gly Ile Tyr Pro Thr Glu Thr Phe Val Thr Ala Val

50 55 60Gly Gln Gly Ash Ile Tyr Ala Asp Phe Leu Ser Lys Ser Leu Lys Asp65 70 75 80Gln Gly His Val Leu Glu Gly Lys Val Gly Gly Thr Ile Gly Gly Ile

85 90 95Ala Tyr Asp Ser Thr Lys Phe Asn Gln Gly Gly Ser Val Ile Tyr Asn

100 105 110Tyr Ile Gly Tyr Trp Asp Gly Tyr Leu Gly Gly Lys Arg Ala Leu Leu

115 120 125Asp Gly Thr Ser Ile His Glu Cys Ala Leu Gly Ser Asp Gly Lys Val

130 135 140Ile Asp Ser Ile Ala Cys Gly Asn Ala Arg Ala Asn Lys Ile Arg Arg145 150 155 160Asn Tyr Leu Met Asn Asn Ala Phe Leu Glu Tyr Arg Tyr Lys Asp Ile

165 170 175Phe Ala Ala Lys Gly Gly Arg Tyr Gln Ser Asn Ala Pro Tyr Met Ser

180 185 190Ser Tyr Thr Gln Gly Phe Glu Ile Ser Ala Lys Ile Lys Asp Lys Asn

195 200 205Glu Gly Ser His Lys Leu Trp Trp Phe Ser Ser Trp Gly Arg Ala Phe

210 215 220Ala Tyr Gly Glu Trp Ile Tyr Asp Phe Tyr Ser Pro Arg Thr Val Ile225 230 235 240Lys Asn Gly Arg Thr Leu Asn Tyr Gly Ile His Leu Val Asp Tyr Thr

245 250 255Tyr Glu Arg Lys Gly Val Ser Val Ser Pro Phe Phe Gln Phe Ser Pro

260 265 270Gly Thr Tyr Tyr Ser Pro Gly Val Ala Val Gly Tyr Asp Ser Asn Pro

275 280 285Asn Phe Asn Gly Val Gly Phe Arg Ser Glu Thr Lys Ala Tyr Ile Leu

290 295 300Leu Pro Val His Ala Pro Leu Lys Arg Asp Thr Tyr Arg Tyr Ala Val305 310 315 320Lys Ala Gly Thr Ala Gly Gln Ser Leu Leu Ile Arg Gln Arg Phe Asp

325 330 335Tyr Asn Glu Phe Asn Phe Gly Gly Ala Phe Tyr Lys Val Trp Lys Asn

340 345 350Ala Asn Ala Tyr Ile Gly Thr Thr Gly Asn Pro Leu Gly Ile AspPhe

355 360 365Trp Thr Asn Ser Val Tyr Asp Ile Gly Gln Ala Leu Ser His Val Val

370 375 380Thr Ala Asp Ala Val Ser Gly Trp Val Phe Gly Gly Gly Val His Lys385 390 395 400Lys Trp Leu Trp Gly Thr Leu Trp Arg Trp Thr Ser Gly Ala Leu Ala

405 410 415Asn Glu Ala Ser Ala Ala Val Asn Val Gly Tyr Lys Ile Ser Lys Ser

420 425 430Leu Thr Ala Ser Val Lys Leu Glu Tyr Leu Gly Val Met Thr His Ser

435 440 445Gly Phe Thr Val Gly Ser Tyr Arg Pro Thr Pro Gly Ser Lys Ala Leu

450455460 Tyr Ser Asp Arg Ser His Leu Met Thr Thr Leu Ser Ala Lys Phe 465470475 (2) SEQ ID NO:856 message

Sequence properties:

(A) length: 479 an amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...479

(xi) sequence representation: SEQ ID NO 856: Met Lys Asn Ser Ala Pro Leu Lys Asn Lys Val Phe Cys Gly Leu Tyr 151015 Val Leu Ser Leu Ser Ala Ser Val Gln Ala Phe Asp Tyr Lys Ile Glu

20 25 30Val Leu Ala Glu Ser Phe Ser Lys Val Gly Phe Asn Lys Lys Lys Ile

35 40 45Asp Ile Ala Arg Gly Ile Tyr Pro Thr Glu Thr Phe Val Thr Ala Val

50 55 60Gly Gln Gly Asn Ile Tyr Ala Asp Phe Leu Ser Lys Ser Leu Lys Asp65 70 75 80Gln Gly His Val Leu Glu Gly Lys Val Gly Gly Thr Ile Gly Gly Ile

85 90 95Ala Tyr Asp Ser Thr Lys Phe Asn Gln Gly Gly Ser Val Ile Tyr Asn

100 105 110Tyr Ile Gly Tyr Trp Asp Gly Tyr Leu Gly Gly Lys Arg Ala Leu Leu

115 120 125Asp Gly Thr Ser Ile His Glu Cys Ala Leu Gly Ser Asp Gly Lys Val

130 135 140Ile Asp Ser Ile Ala Cys Gly Asn Ala Arg Ala Asn Lys Ile Arg Arg145 150 155 160Asn Tyr Leu Met Asn Asn Ala Phe Leu Glu Tyr Arg Tyr Lys Asp Ile

165 170 175Phe Ala Ala Lys Gly Gly Arg Tyr Gln Ser Asn Ala Pro Tyr Met Ser

180 185 190Ser Tyr Thr Gln Gly Phe Glu Ile Ser Ala Lys Ile Lys Asp Lys Asn

195 200 205Glu Gly Ser His Lys Leu Trp Trp Phe Ser Ser Trp Gly Arg Ala Phe

210 215 220Ala Tyr Gly Glu Trp Ile Tyr Asp Phe Tyr Ser Pro Arg Thr Val Ile225 230 235 240Lys Asn Gly Arg Thr Leu Asn Tyr Gly Ile His Leu Val Asp Tyr Thr

245 250 255Tyr Glu Arg Lys Gly Val Ser Val Ser Pro Phe Phe Gln Phe Ser Pro

260 265 270Gly Thr Tyr Tyr Ser Pro Gly Val Ala Val Gly Tyr Asp Ser Asn Pro

275 280 285Asn Phe Asn Gly Val Gly Phe Arg Ser Glu Thr Lys Ala Tyr Ile Leu

290 295 300Leu Pro Val His Ala Pro Leu Lys Arg Asp Thr Tyr Arg Tyr Ala Val305 310 315 320Lys Ala Gly Thr Ala Gly Gln Ser Leu Leu Ile Arg Gln Arg Phe Asp

325 330 335Tyr Asn Glu Phe Asn Phe Gly Gly Ala Phe Tyr Lys Val Trp Lys Asn

340 345 350Ala Asn Ala Tyr Ile Gly Thr Thr Gly Asn Pro Leu Gly Ile Asp Phe

355 360 365Trp Thr Asn Ser Val Tyr Asp Ile Gly Gln Ala Leu Ser His Val Val

370 375 380Thr Ala Asp Ala Val Ser Gly Trp Val Phe Gly Gly Gly Val His Lys385 390 395 400Lys Trp Leu Trp Gly Thr Leu Trp Arg Trp Thr Ser Gly Ala Leu Ala

405 410 415Asn Glu Ala Ser Ala Ala Val Asn Val Gly Tyr Lys Ile Ser Lys Ser

420 425 430Leu Thr Ala Ser Val Lys Leu Glu Tyr Leu Gly Val Met Thr His Ser

435 440 445Gly Phe Thr Val Gly Ser Tyr Arg Pro Thr Pro Gly Ser Lys Ala Leu

450455460 Tyr Ser Asp Arg Ser His Leu Met Thr Thr Leu Ser Ala Lys Phe 465470475 (2) SEQ ID NO:857 information

Sequence properties:

(A) length: 171 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...171

(xi) sequence representation: SEQ ID NO 857: Met Gly Leu Lys Asn Leu Ser Thr Leu Leu Val Phe Leu Phe Phe Cys 151015 Leu Gly Cys Val Ser Asn Phe Asn Glu Asp Thr Tyr Thr Leu Asp Leu

20 25 30Val Leu Glu Lys Lys Ile Gln Ala Ser Arg Lys Gly Glu Ile Thr Gln

35 40 45Asp Asn Val Pro Ile Ile Thr Ala Ile Ala Thr His Leu Asn Asp Val

50 55 60Asp Ser Gly Thr Tyr Tyr Asp His Glu Tyr Phe Leu Val Glu Ile Phe65 70 75 80Thr Gln Asn Asn Asp Trp Ile Asp Asp Gly Tyr Ile Ser Tyr Glu Leu

85 90 95Phe Gly Thr Lys Pro Thr Gly Ser Glu Pro Leu Trp Val Arg Glu Ile

100 105 110Thr Arg Asp Glu Phe Asp Gly Ile Leu Glu Thr Thr Asn Arg Trp Ser

115 120 125Arg Ala Phe Leu Ile Ala Phe Asp Lys Leu Asp Tyr Leu Ala Val Gln

130 135 140Glu Ala Lys Leu Glu Leu Asp Ala Tyr Ser Leu Gly Lys Ile Val Phe145 150155 160Asn Phe Ala Tyr Gln Val Pro Leu Pro Gln Phe

165170 (2) information of SEQ ID NO:858

Sequence properties:

(A) length: 84 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...84

(xi) sequence representation: SEQ ID NO:858: Val Asn Lys Lys His Arg Leu Ala Phe Leu Gly Leu Ile Val Gly Val 151015 Leu Phe Phe Phe Ser Ala Cys Gln His Arg Leu His Met Gly Tyr Tyr

20 25 30Ser Glu Val Thr Gly Asp Tyr Leu Phe Asn Tyr Asn Ser Thr Ile Val

35 40 45Val Ala Tyr Asp Arg Ser Asp Ala Met Thr Ser Tyr Tyr Ile Asn Val

505560 Ile Val Tyr Glu Leu Gln Lys Leu Gly Phe Tyr Asn Val Phe Thr Gln 65707580 Ala Asn Ser Arg (2) SEQ ID NO:859 information

Sequence properties:

(A) length: 252 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...252

(xi) sequence representation: SEQ ID NO 859: Met Gln Tyr Lys Lys Asn Lys Lys Arg Tyr Tyr His Leu Ala Leu Gly 151015 Ile Leu Phe Cys Asn Gly Leu Ser Leu Lys Ala Leu Glu Ile Ala Val

20 25 30Lys Pro Phe Gly Tyr Leu Gly Leu Leu Tyr Asn Gln Gly Thr Gln Lys

35 40 45Asn Pro His Ser Tyr Val Gly Ala Leu Ala Arg Leu Gly Val Asp Phe

50 55 60Ser Tyr Ser Asn Gly Trp Ser Phe Gly Ile Gly Ala Ile Gly Ala Trp65 70 75 80Asn Ile Tyr Asn Lys Gln Arg Leu Ala Asn Leu Tyr Ile Ser Leu Gly

85 90 95Asn Phe Phe Gly Asn Pro Asn Asn Val Lys Pro Tyr Leu Ser Ala Gly

100 105 110Asp Val Ser Asp Ala Tyr Leu Gln Tyr Ala Asn Gln Arg Phe Lys Ile

115 120 125Ala Leu Gly Arg Phe Asn Thr Asp Phe Val Asp Phe Asp Trp Ile Gly

130 135 140Gly Asn Ile Gln Gly Val Ser Val Ala Phe Lys Gln Asn Ser Met Arg145 150 155 160Tyr Phe Gly Ile Phe Met Asp Ser Met Leu Tyr Asn Gly His Gln Ile

165 170 175Asn Lys Glu Gln Gly Asn Arg Ile Ala Thr Ser Leu Asn Ala Leu Ala

180 185 190Ser Tyr Asp Pro Val Ser Lys Arg Leu Tyr Val Gly Gly Glu Val Phe

195 200 205Val Leu Gly Ala Glu Tyr Lys Asn Lys Asn Leu Ile Phe Val Pro Phe

210 215 220Ile Leu Thr Asp Thr Arg Leu Pro Leu Pro Thr Gln Asn Val Leu Val225 230 235 240Gln Val Gly Gly Lys Leu Glu Tyr Arg Arg Phe Phe

245631 (2) SEQ ID NO 860 information

Sequence properties:

(A) length: 231 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...231

(xi) sequence representation: SEQ ID NO 860: Met Val Gln Lys Ile Gly Ile Leu Gly Ala Met Arg Glu Glu Ile Thr 151015 Pro Ile Leu Glu Leu Phe Gly Val Asp Phe Glu Glu Ile Pro Leu Gly

20 25 30Gly Asn Val Phe His Lys Gly Val Tyr Hls Asn Lys Glu Ile Ile Val

35 40 45Ala Tyr Ser Lys Ile Gly Lys Val His Ser Thr Leu Thr Thr Thr Ser

50 55 60Met Ile Leu Ala Phe Gly Val Gln Lys Val Leu Phe Ser Gly Val Ala65 70 75 80sly Ser Leu Val Lys Asp Leu Lys Ile Asn Asp Leu Leu Val Ala Thr

8590 95Gln Leu Val Gln His Asp Val Asp Leu Ser Ala Phe Asp His Pro Leu

100 105 110Gly Phe Ile Pro Glu Ser Ala Ile Phe Ile Glu Thr Ser Gly Ser Leu

115 120 125Asn Ala Leu Ala Lys Lys Ile Ala Asn Glu Gln His Ile Ala Leu Lys

130 135 140Glu Gly Val Ile Ala Ser Gly Asp Gln Phe Val His Ser Lys Glu Arg145 150 155 160Lys Glu Phe Leu Val Ser Glu Phe Lys Ala Ser Ala Val Glu Met Glu

165 170 175Gly Ala Ser Val Ala Phe Val Cys Gln Lys Phe Gly Val Pro Cys Cys

180 185 190Val Leu Arg Ser Ile Ser Asp Asn Ala Asp Glu Lys Ala Gly Met Ser

195 200 205Phe Asp Glu Phe Leu Glu Lys Ser Ala His Thr Ser Ala Lys Phe Leu

210215220 Lys Ser Met Val Asp Glu Leu 225230 (2) SEQ ID NO:861 information

Sequence properties:

(A) length: 225 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...225

(xi) sequence representation: 86l of SEQ ID NO Met Arg Ala Thr Ala Ile Lys Ile Phe Ser Phe Ser Ser Ala Leu Ala 151015 Leu Leu Leu Gln Gly Cys Leu Ser Ile Asn Leu Lys Gln Met Leu Pro

20 25 30Glu Ile Arg Thr Tyr Asp Leu Asn Ala Ser Ser Phe Glu Met Thr Gln

35 40 45Cys Pro Lys Pro Leu Thr Glu Val Arg Leu Ile Ser Ile Leu Ser Ala

50 55 60Asp Leu Phe Asn Thr Lys Glu Ile Val Phe Lys Ala Gln Asp Gly Gln65 70 75 80Ile Thr His Gly Lys His Gln Lys Trp Ile Asp Leu Pro Arg Asn Met

85 90 95Leu Lys Thr Met Phe Met Gln Glu Ala Gln Lys Ala Cys Leu Gly Val

100 105 110Ala Leu Pro Pro Tyr Gly Ala Gly Ala Pro Thr Tyr Ala Val Arg Phe

115 120 125Thr Ile Leu Ssr Phe Ser Leu Leu Glu Lys Glu Asn Ser Thr Tyr Arg

130 135 140Ala Glu Phe Ala Leu Gly Tyr Asp Ile Ser Val Lys Gly Asp Ser His145 150 155 160Ser Gly Val Ile Ile Lys His Glu Asn Ile Ser Sar Leu Glu Asn Lys

165 170 175Thr Thr Lys Thr Ser Lys Asn Gly Ser Gln Asp Phe Gln Glu Ser Ala

180 185 190Ile Gln Ser Leu Gln His Val Ser Thr Gln Ala Met Gln Glu Ala Ile

195 200 205Ser Leu Ile Lys Lys Ala Val Glu Ala Gln Ser Val Ser Pro Leu Lys

210215220 Lys225(2) SEQ ID NO:862 information

Sequence properties:

(A) length: 271 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...271

(xi) sequence representation: SEQ ID NO 862: Leu Glu Arg His Val Asn Tyr Thr Leu Ile Gly Gly Leu Phe Phe Leu 151015 Cys Leu Val Cys Met Val Gly Phe Ile Leu Trp Leu Gly His Leu Gly

20 25 30Leu Asp Asp Gly Lys Tyr Tyr Glu Tyr Val Val Tyr Thr Asp Lys Asp

35 40 45Leu Gly Gly Ile Ala Thr Asn Ser Pro Ile Asn Tyr Lys Gly Ile Gln

50 55 60Val Gly Asn Val Ile Lys Val Gly Phe Ala Lys Asp Lys Val Gly Val65 70 75 80Val Arg Leu Asp Leu Met Ile Lys Ser Ser Val Lys Ile Arg Lys Asp

85 90 95Ser Lys Val Ala Val Ser Ser Arg Gly Phe Met Gly Leu Lys Phe Leu

100 105 110Ala Leu Glu Gln Ser His Asn Glu Glu Phe Tyr Gly Ser Gly Asp Lys

115 120 125Gly Glu Arg Ile Leu Ile Phe Lys Glu Gly Leu Met Asp Arg Leu Ser

130 135 140Gly Asp Ala Asn Gln Val Val Gln Glu Val Met Lys Ala Ile Arg Asn145 150155 160Val Asn Arg Ile Leu Asp Asp Glu Asn Val Glu Lys Phe Lys His Ile

165 170 175Leu Ala Ser Val Asp Asp Leu Ile Ala Asn Leu Asp Ser Arg Lys Thr

180 185 190Gln Phe Asp Ser Leu Ile Asn Asn Ala Asn Asn Leu Val Ser Asn Val

195 200 205Asn Asn Val Ala Leu Asp Val Asp Lys Arg Val Lys Gln Gly Gln Tyr

210 215 220Asp Phe Lys Ala Met Phe Thr Pro Leu Ile Met Gln Ala Gln Leu Ser225 230 235 240Leu Arg Asn Ile Asp Asn Phe Val Glu Lys Gly Ser Ala Leu Ile Asp

245 250 255Lys Phe Asp Ala Asn Pro Tyr Lys Thr Ile Phe Gly Glu Arg Lys

260265270 (2) SEQ ID NO 863 message

Sequence properties:

(A) length: 350 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 350

(xi) Sequence representation: 863, Met Lys Lys Thr Ile Leu Leu Ser Ala Leu Leu Ala Phe Ser Cys Ala 151015, His Ala Leu Ser Asp Met Asp Leu Ile Lys Lys Ala Lys Glu Ser Gln SEQ ID NO

2025 30Leu Glu Pro Met Pro Met Gly Lys Ala Leu Lys Glu Tyr Gln Ile Lys

35 40 45Lys Thr Arg Asp Val Gly Ile Gly Ala Lys Asn Ser Glu Ile Met Thr

50 55 60Ser Ala Gln Val Glu Leu Gly Lys Met Leu Tyr Phe Asp Pro Arg Ile65 70 75 80Ser Thr Ser Tyr Leu Val Ser Cys Asn Thr Cys His Asn Leu Gly Leu

85 90 95Gly Gly Val Asp Leu Ile Pro Ser Ala Ile Gly Ser Gln Trp Lys Lys

100 105 110Asn Pro His Leu Leu Ser Ser Pro Thr Val Tyr Asn Ser Val Phe Asn

115 120 125Asp Val Gln Phe Trp Asp Gly Arg Val Thr His Leu Asn Glu Gln Ala

130 135 140Gln Gly Pro Ile Gln Ser Ser Phe Glu Met Gly Ala Asp Pro Lys Val145 150 155 160Val Val Glu Lys Ile Asn Ser Ile Pro Gly Tyr Val Lys Leu Phe Arg

165 170 175Lys Ala Tyr Gly Ser Lys Val Lys Ile Asp Phe Lys Leu Ile Ala Asp

180 185 190Ser Ile Ala Met Phe Glu Ala Thr Leu Ile Thr Pro Ser Arg Tyr Asp

195 200 205Asp Phe Leu Arg Gly Asn Pro Lys Ala Leu Ser Lys Ala Glu Lys Glu

210 215 220Gly Leu Asp Leu Phe Ile Ser Lys Gly Cys Val Ala Cys His Asn Gly225 230 235 240Ile Asn Leu Gly Gly Thr Met Gln Pro Phe Gly Val Val Lys Pro Tyr

245250 255Lys Phe Ala Asn Val Gly Asp Phe Lys Gly Asp Lys Asn Gly Leu Val

260 265 270Lys Val Pro Thr Leu Arg Asn Ile Thr Glu Thr Met Pro Tyr Phe His

275 280 285Asn Gly Gln Phe Trp Asp Val Lys Asp Ala Ile Lys Glu Met Gly Ser

290 295 300Ile Gln Leu Gly Ile Glu Ile Ser Asp Ala Glu Ala Lys Lys Ile Glu305 310 315 320Thr Phe Phe Glu Ala Leu Lys Gly Lys Lys Pro Lys Ile Ile Tyr Pro

325 330 335Glu Leu Pro Val Met Thr Asp Lys Thr Pro Lys Pro Ser Phe

340345350 (2) SEQ ID NO:864 information

Sequence properties:

(A) length: 73 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...73

(xi) sequence representation: 864 SEQ ID NO: Met Met Asp Leu Glu Ser Leu Arg Gly Phe Ala Tyr Ala Phe Phe Thr 151015 Ile Leu Phe Thr Leu Phe Leu Tyr Ala Tyr Ile Phe Ser Met Tyr Arg

20 25 30Lys Gln Lys Lys Gly Ile Val Asp Tyr Glu Arg Tyr Gly Tyr Leu Ala

35 4045Leu Asn Asp Ala Leu Glu Asp Glu Leu Ile Glu Pro Arg His Lys Glu

505560 Val His Asp Lys Gly Ile Lys Glu Ser 6570 (2) SEQ ID NO:865 information

Sequence properties:

(A) length: 275 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...275

(xi) sequence representation: SEQ ID NO 865: Leu Leu Asp Val Lys Ala Asn Ser Pro Ala Tyr Gln Ala Val Leu Leu 151015 Ala Leu Asn Ala Ala Val Gly Leu Trp Gln Val Thr Ser Tyr Ala Phe

20 25 30Thr Ala Cys Gly Pro Gly Ser Asn Glu Asn Ala Asn Gly Gly Ile Gln

35 40 45Thr Phe Asn Asn Val Pro Gly Gln Asn Thr Thr Thr Ile Thr Cys Asn

50 55 60Ser Tyr Tyr Glu Pro Gly Mis Gly Gly Pro Ile Ser Thr Glu Asn Tyr65 70 75 80Ala Ile Ile Asn Lys Ala Tyr Gln Ile Ile Gln Lys Ala Leu Thr Ala

85 90 95Asn Gly Glu Gly Ile Pro Val Leu Ser Asn Thr Thr Thr Lys Leu Asp

100 105 110Phe Thr Ile Asn Gly Asp Lys Arg Thr Gly Gly Glu Pro Asn Lys Lys

115120 125Leu Val Tyr Pro Trp Ser His Gly Lys Pro Ile Ser Thr Ser Trp Asn

130 135 140Ala Thr Ile Thr Val Pro Thr Thr Glu Asn Ile Asn Thr Thr Asn Ser145 150 155 160Ala Gln Glu Leu Leu Lys Gln Ala Ser Ile Ile Ile Thr Thr Leu Asn

165 170 175Ser Ala Cys Pro Asn Phe Gln Asn Gly Gly Ser Gly Tyr Trp Ala Gly

180 185 190Ile Ser Gly Asn Gly Thr Met Cys Gly Met Phe Lys Asn Glu Ile Ser

195 200 205Ala Ile Gln Gly Met Ile Ala Asn Ala Gln Glu Ala Val Ala Gln Ala

210 215 220Lys Ile Val Ser Glu Asn Thr Gln Asn Gln Asn Ser Leu Asp Ala Glu225 230 235 240Asn His Ser Thr Pro Thr Gln Thr Leu Val Leu Leu Lys Ala Cys Ser

245 250 255Lys Thr Arg Ser Pro Ser Gly Asp Phe Lys Pro Ser Arg Thr Ser Gly

260 265 270Glu Lys Leu

275(2) SEQ ID NO:866 information

Sequence properties:

(A) length: 90 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...90

(xi) sequence representation: 866: Met Leu Thr Ile Glu Thr Ser Lys Lys Phe Asp Lys Asp Leu Lys Ile 151015 Leu Val Lys Asn Gly Phe Asp Leu Lys Leu Leu Tyr Lys Val Val Gly SEQ ID NO

20 25 30Asn Leu Ala Thr Glu Gln Pro Leu Glu Pro Lys Tyr Lys Asp His Pro

35 40 45Leu Lys Gly Ala Leu Lys Asp Phe Arg Glu Cys His Leu Lys Pro Asp

50 55 60Leu Leu Leu Val Tyr Gln Ile Lys Lys Gln Glu Asn Thr Leu Phe Leu65 70 75 80Val Arg Leu Gly Ser His Ser Glu Leu Phe

8590 (2) the SEQ ID NO 867 message

Sequence properties:

(A) length: 100 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...100

(xi) sequence representation: 867: Met Leu Glu Ile Glu Leu Lys Lys Lys Phe Thr Lys Asp Leu Lys Lys 151015 His Ile Leu Asn Gln Lys Ile Glu Leu Glu Val Phe Asp Leu Val Val SEQ ID NO

20 25 30Glu Asn Leu Arg Asn Gln Ile Pro Leu Asp Lys Arg Phe Lys Asp His

35 40 45Ala Leu Ser Gly Thr Tyr Lys Gly Cys Arg Glu Arg His Ile Lys Pro

50 55 60Asp Val Leu Leu Val Tyr Arg Val Lys Gly Asn Val Leu Thr Leu Val65 70 75 80Arg Leu Gly Ser His Ser Glu Leu Phe Cys Lys Pro Pro Thr Pro Leu

85 90 95Ile Thr Leu Lys

100(2) SEQ ID NO 868 message

Sequence properties:

(A) length: 89 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...89

(xi) sequence representation: SEQ ID NO. 868: Leu Val Val Ser Gly Ser Leu Gln Asn Ile Val Arg Ser Phe Leu Arg 151015 Arg Ile Ser Val Phe Phe Ile Ile Asp Phe Ile Asn Phe Ile Phe Val

20 25 30Ile Asp Gln Ile Ile His Phe Phe Gly Asp Phe Phe Ile Phe Phe Phe

35 40 45Met Leu Asn Leu Phe Tyr Ile Leu Ile Arg Leu Ile Asp Leu Ile Val

50 55 60Leu Ser Gly Phe Ser Val Val Leu Val Arg Leu Gly Arg Phe Phe Arg65 70 75 80Leu Ile Phe Ala Gly Ala Gln His Ala

85(2) the SEQ ID NO 869 message

Sequence properties:

(A) length: 479 an amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...479

(xi) sequence representation: 869: Met Lys Lys Ser Leu Cys Leu Ser Phe Phe Leu Thr Phe Ser Asn Pro 151015 Leu Gln Ala Leu Val Ile Glu Leu Leu Glu Glu Ile Lys Thr Ser Pro SEQ ID NO

20 25 30His Lys Gly Thr Phe Lys Ala Lys Val Leu Asp Ser Lys Glu Pro Arg

35 40 45Gln Val Leu Gly Val Tyr Asn Ile Ser Pro His Lys Lys Leu Thr Leu

50 55 60Thr Ile Thr His Ile Ser Thr Ala Ile Val Tyr Gln Pro Leu Asp Glu65 70 75 80Lys Leu Ser Leu Glu Thr Thr Leu Ser Pro Asn ArG Pro Thr Ile Pro

85 90 95Arg Asn Thr Gln Ile Val Phe Ser Ser Lys Glu Leu Lys Glu Pro His

100 105 110Ser Asn Pro Ile Pro Ser Leu Asn Ala Pro Met Gln Lys Pro Gln Asn

115 120 125Lys Pro Ser Ser Ser Gln Gln Ser Pro Gln Asn Phe Ser Tyr Pro Glu

130 135 140Ser Lys Leu Gly Ser Lys Asn Ser Lys Asn Ser Leu Leu Gln Pro Leu145 150 155 160Val Thr Pro Ser Lys Val Ser Pro Thr Asn Glu Val Lys Thr Pro Thr

165 170 175Asn Asp Ala Asn Pro Pro Leu Lys His Ser Ser Gln Asp Gln Glu Asn

180 185 190Asn Leu Phe Val Ala Pro Pro Thr Glu Lys Thr Leu Pro Asn Asn Thr

195 200 205Ser Ser Ala Asp Ala Ser Glu Aan Asn Glu Ser Asn Glu Asn Arg Asp

210 215 220Asn Val Glu Lys Gln Ala Ile Arg Asp Pro Asn Ile Lys Glu Phe Ala225 230 235 240Cys Gly Lys Trp Val Tyr Asp Asp Glu Asn Leu Gln Ala Tyr Arg Pro

245 250 255Ser Ile Leu Lys Arg Val Asp Lys Asp Lys Glu Ile Thr Thr Asp Ile

260 265 270Thr Pro Cys Asp Tyr Ser Thr Ala Glu Asn Lys Ser Gly Lys Ile Ile

275 280 285Thr Pro Tyr Thr Lys Ile Ser Val His Lys Thr Glu Pro Leu Glu Asp

290 295 300Pro Gln Thr Phe Glu Ala Lys Asn Asn Phe Ala Ile Leu Gln Ala Arg305 310 315 320Ser Ser Thr Glu Lys Cys Lys Arg Ala Arg Ala Arg Lys Asp Gly Thr

325 330 335Thr Arg Gln Cys Tyr Leu Ile Glu Glu Pro Leu Lys Gln Ala Trp Glu

340 345 350Ser Glu Tyr Glu Ile Thr Thr Gln Leu Val Lys Ala Ile Tyr Glu Arg

355 360 365Pro Lys Gln Asp Asp Gln Val Glu Pro Thr Phe Tyr Glu Thr Ser Glu

370 375 380Leu Ala Tyr Ser Ser Thr Arg Lys Ser Glu Ile Thr Arg Asn Glu Leu385 390 395 400Asn Leu Asn Glu Lys Phe Met Glu Phe Val Glu Val Tyr Glu Gly His

405 410 415Tyr Leu Asn Asp Ile Ile Lys Glu Ser Ser Glu Tyr Lys Glu Trp Val

420 425 430Lys Asn His Val Arg Phe Lys Glu Gly Val Cys Met Ala Leu Glu Ile

435 440 445Glu Glu Gln Pro Arg Ala Lys Ser Thr Pro Leu Ser Ile Glu Asn Ser

450455460 Arg Val Val Cys Val Lys Lys Gly Asn Tyr Leu Phe Asn Glu Val 465470475 (2) SEQ ID NO:870 information

Sequence properties:

(A) length: 479 an amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...479

(xi) sequence representation: 870: Met Lys Lys Ser Leu Cys Leu Ser Phe Phe Leu Thr Phe Ser Asn Pro 151015 Leu Gln Ala Leu Val Ile Glu Leu Leu Glu Glu Ile Lys Thr Ser Pro SEQ ID NO

20 25 30His Lys Gly Thr Phe Lys Ala Lys Val Leu Asp Ser Lys Glu Pro Arg

35 40 45Gln Val Leu Gly Val Tyr Asn Ile Ser Pro His Lys Lys Leu Thr Leu

50 55 60Thr Ile Thr His Ile Ser Thr Ala Ile Val Tyr Gln Pro Leu Asp Glu65 70 75 80Lys Leu Ser Leu Glu Thr Thr Leu Ser Pro Asn Arg Pro Thr Ile Pro

85 90 95Arg Asn Thr Gln Ile Val Phe Ser Ser Lys Glu Leu Lys Glu Pro His

100 105 110Ser Asn Pro Ile Pro Ser Leu Asn Ala Pro Meu Gln Lys Pro Gln Asn

115 120 125Lys Pro Ser Ser Ser Gln Gln Ser Pro Gln Asn Phe Ser Tyr Pro Glu

130 135 140Ser Lys Leu Gly Ser Lys Asn Ser Lys Asn Ser Leu Leu Gln Pro Leu145 150 155 160 Val Thr Pro Ser Lys Val Ser Pro Thr Asn Glu Val Lys Thr Pro Thr

165 170 175Asn Asp Ala Asn Pro Pro Leu Lys His Ser Ser Gln Asp Gln Glu Asn

180 185 190Asn Leu Phe Val Ala Pro Pro Thr Glu Lys Thr Leu Pro Asn Asn Thr

195 200 205Ser Ser Ala Asp Ala Ser Glu Asn Asn Glu Ser Asn Glu Asn Arg Asp

210 215 220Asn Val Glu Lys Gln Ala Ile Arg Asp Pro Asn Ile Lys Glu Phe Ala225 230 235 240Cys Gly Lys Trp Val Tyr Asp Asp Glu Asn Leu Gln Ala Tyr Arg Pro

245 250 255Ser I1e Leu Lys Arg Val Asp Lys Asp Lys Glu Ile Thr Thr Asp Ile

260 265 270Thr Pro Cys Asp Tyr Ser Thr Ala Glu Asn Lys Ser Gly Lys Ile Ile

275 280 285Thr Pro Tyr Thr Lys Ile Ser Val His Lys Thr Glu Pro Leu Glu Asp

290 295 300Pro Gln Thr Phe Glu Ala Lys Asn Asn Phe Ala Ile Leu Gln Ala Arg305 310 315 320Ser Ser Thr Glu Lys Cys Lys Arg Ala Arg Ala Arg Lys Asp Gly Thr

325 330 l35Thr Arg Gln Cys Tyr Leu Ile Glu Glu Pro Leu Lys Gln Ala Trp Glu

340 345 350Ser Glu Tyr Glu Ile Thr Thr Gln Leu Val Lys Ala Ile Tyr Glu Arg

355 360 365Pro Lys Gln Asp Asp Gln Val Glu Pro Thr Phe Tyr Glu Thr Ser Glu

370 375 380Leu Ala Tyr Ser Ser Thr Arg Lys Ser Glu Ile Thr Arg Asn Glu Leu385 390 395 400Asn Leu Asn Glu Lys Phe Met Glu Phe Val Glu Val Tyr Glu Gly His

405 410 415Tyr Leu Ash Asp Ile Ile Lys Glu Ser Ser Glu Tyr Lys Glu Trp Val

420 425 430Lys Asn His Val Arg Phe Lys Glu Gly Val Cys Met Ala Leu Glu Ile

435 440 445Glu Glu Gln Pro Arg Ala Lys Ser Thr Pro Leu Ser Ile Glu Asn Ser

450455460 Arg Val Val Cys Val Lys Lys Gly Asn Tyr Leu Phe Asn Glu Val 465470475 (2) SEQ ID NO:871 information

Sequence properties:

(A) length: 300 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...300

(xi) sequence representation: SEQ ID NO:871: Met Arg Lys Thr Ile Ser Ala Leu Phe Leu Ser Ala Cys Ile Gly Leu 151015 Ser Ser Val His Ala Ser Asn Ala Leu Ile Leu Gln Thr Asp Phe Ser

20 25 30Leu Lys Asp Gly Ala Val Ser Ala Met Lys Gly Val Ala Phe Ser Val

35 40 45Asp Ser Asn Leu Lys Ile Phe Asp Leu Thr His Glu Ile Pro Pro Tyr

50 55 60Asn Ile Trp Glu G1y Ala Tyr Arg Leu Tyr Gln Thr Ala Ser Tyr Trp65 70 75 80Pro Lys Gly Ser Val Phe Val Ser Val Val Asp Pro Gly Val Gly Thr

85 90 95Asn Arg Lys Ser Val Val Leu Lys Thr Lys Asn Gly Gln Tyr Phe Val

100 105 110Ser Pro Asp Asn Gly Thr Leu Thr Leu Val Ala Gln Thr Leu Gly Ile

1l5 120 125Asp Ser Val Arg Glu Ile Asp Glu Lys Ala Asn Arg Leu Lys Gly Ser

130 135 140Glu Lys Ser Tyr Thr Phe His Gly Arg Asp Val Tyr Ala Tyr Thr Gly145 150 155160Ala Arg Leu Ala Ser Gly Ala Ile Thr Phe Glu Gln Val Gly Pro Glu

165 170 175Leu Pro Ile Lys Val Val Glu Ile Pro Tyr Gln Lys Ala Lys Ala Thr

180 185 190Lys Gly Gly Val Lys Gly Asn Ile Pro Ile Leu Asp Ile Gln Tyr Gly

195 200 205Asn Val Trp Ser Asn Ile Ser Asp Lys Leu Leu Asn Gln Ala Gly Ile

210 215 220Lys Arg Asn Asp Thr Val Cys Val Thr Ile Phe Lys Asn Ser Lys Lys225 230 235 240Gln Tyr Glu Gly Lys Met Pro Tyr Val Ala Ser Phe Gly Asp Val Pro

245 250 255Glu Gly Gln Pro Leu Val Tyr Leu Asn Ser Leu Leu Asn Val Ser Val

260 265 270Ala Leu Asn Met Asp Asn Phe Ala Gln Lys His Gln Ile Lys Ser Gly

275 280 285Ala Asp Trp Asn Ile Asp Ile Lys Lys Cys Ala Lys

290295300 (2) information of SEQ ID NO:872

Sequence properties:

(A) length: 156 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...156

(xi) sequence representation: 872: Leu Thr Lys Lys Phe Met Ser Trp Met Val Val Ile Gly Ala Leu Ile 151015 Cys Val Leu Leu Gly Val Phe Ile Phe Phe Thr Ser Met Ser Val Lys SEQ ID NO

20 25 30Lys Ser Leu Thr Ala Tyr Leu Asn Ala Tyr Leu Glu Gln Arg Pro Asn

35 40 45Ile Glu Gly Met Gly Ile Ile Gly Val Pro Phe Lys Cys Glu Arg Phe

50 55 60Phe Lys Ile Ala Cys Val Ser Lys Glu Leu Arg Phe Leu Asp Pro Gln65 70 75 80Asn Ser Pro Ile Met Asp Phe Lys Asn Leu Lys Ile Lys Leu His Ser

85 90 95Leu Asp Lys Ser Ser Leu Thr Leu Ser Ile His Ser Gln Ile Gln Ser

100 105 110Pro Ile Leu Glu Gln Ser Ile Gln Gln Lys Ile Ser Gln Ile Pro Leu

115 120 125Lys Asn Leu Asn Ala Leu Leu Glu Lys Phe Lys Pro Thr Arg Leu Asn

130135140 Cys Ser Leu Thr Phe Asn Ala Leu Asp Glu Lys Thr 145150155 (2) SEQ ID NO:873 information

Sequence properties:

(A) length: 285 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _feature

(B) Position: 1...285

(xi) sequence representation: 873: Met Gln Asp Phe Ile Lys Ile Phe Ile Gln Glu Val Val Set Thr Leu 151015 Glu Gly Leu Val Gly Lys Ala Pro Ser Val Gly Leu Glu Lys Glu Val SEQ ID NO

20 25 30Ser Asn Asn Glu Glu Ala Ser Leu Ile Ser Thr Pro Tyr Ala Arg Val

35 40 45Lys Ile Ser Ala Ile Glu Lys Asn Glu Ser Pro Ile Glu Leu Leu Ala

50 55 60Pro Val Asp Leu Val Thr Ala Leu Ser Asp Leu Met Leu Gly Gly Glu65 70 75 80Gly Ala Ser Lys Glu Glu Met Asp Asn Asp Asp Leu Asp Ala Phe Lys

85 90 95Glu Met Ala Ser Asn Ile Phe Gly Ala Ile Ala Thr Ser Leu Lys Ser

100 105 110Gln Glu Leu Leu Pro Lys Leu Asn Phe Thr Thr Thr Asn Ala Glu Ile

115 120 125Ala Lys Glu Leu Pro Lys Lys Glu Asp Tyr Ala Lys Ala Met Val Phe

130 135 140Ser Phe Lys Met Glu Ala Ile Lys Glu Ser Gln Ile Val Leu Leu Ile145 150 155 160Thr Ser Ala Phe Glu Gly Gln Phe Glu Lys Thr His Lys Glu Glu Lys

165 170 175Glu Glu Thr Thr Lys Ser Ala Thr Glu Glu Thr Lys Tnr His Asp Ala

180 185 190Ser Leu Glu Asn Ile Glu Ile Arg Asn Ile Ser Met Leu Leu Asp Val

195 200 205Lys Leu Asn Val Lys Val Arg Ile Gly Gln Lys Lys Met Ile Leu Lys

210 215 220Asp Val Val Ser Met Asp Ile Gly Ser Val Val Glu Leu Asp Gln Leu225 230 235 240Val Asn Asp Pro Leu Glu Ile Leu Val Asp Asp Lys Val Ile Ala Lys

245 250 255Gly Glu Val Val Ile Val Asp Gly Asn Phe Gly Ile Gln Ile Thr Asp

260 265 270Ile Gly Thr Lys Lys Glu Arg Leu Glu Gln Leu Lys Asn

275280285 (2) SEQ ID NO:874 message

Sequence properties:

(A) length: 329 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...329

(xi) sequence representation: SEQ ID NO of 874: Met Thr Thr Lys Arg Val Asn Thr Ala Thr Asn Lys Ile Met Thr Leu 151015 Asn Thr Phe Leu Asp Thr Cys Phe Leu Phe Phe Ile Ser Ile Leu Phe

20 25 30Tyr Leu Ser Ile Pro Ile Tyr Pro Asn Lys Val Val Val Val Pro Gln

35 40 45Gly Ser Leu Lys Lys Val Phe Phe Ser Leu Lys Glu Gln Gly Val Asp

50 55 60Ile Asn Ala Leu Asp Leu Leu Leu Leu Arg Leu Met Gly Met Pro Lys6570 75 80Lys Gly Tyr Ile Asp Met Gly Asp Gly Ala Leu Arg Lys Gly Asp Pha

85 90 95Leu Val Arg Leu Ile Lys Ala Lys Thr Ala Gln Lys Ser Val Thr Leu

100 105 110Ile Pro Gly Glu Thr Arg Tyr Phe Phe Thr Gln Ile Leu Ser Glu Thr

115 120 125Tyr Gln Leu Glu Thr Ser Asp Leu Asn Glu Ala Tyr Glu Ser Ile Ala

130 135 140Pro Arg Leu Asn Gly Ala Val Ile Glu Asp Gly Val Ile Trp Pro Aspl45 150 155 160Thr Tyr His Leu Pro Leu Gly Glu Asp Ala Phe Lys Ile Met Gln Thr

165 170 175Leu Ile Gly Gln Ser Met Lys Lys His Glu Ala Leu Ser Lys Gln Trp

180 185 190Leu Gly Tyr Tyr His Lys Glu Glu Trp Phe Glu Lys Ile Ile Leu Ala

195 200 205Ser Ile Val Gln Lys Glu Ala Ala Asn Val Glu Glu Met Pro Leu Ile

210 215 220Ala Ser Val Ile Phe Asn Arg Leu Lys Lys Gly Met Pro Leu Gln Met225 230 235 240Asp Gly Ala Leu Asn Tyr Gln Glu Phe Ser His Ala Lys Val Thr Lys

245 250 255Glu Arg Ile Lys Thr Asp Asn Thr Pro Tyr Asn Thr Tyr Lys Phe Lys

260 265 270Gly Leu Pro Lys Asn Pro Val Gly Ser Val Ser Leu Glu Ala Val Arg

275 280 285Ala Val Val Phe Pro Lys Lys Thr Asp Phe Leu Tyr Phe Val Lys Met

290 295 300Pro Asp Lys Lys His Ala Phe Ser Ala Thr Tyr Lys Glu His Leu Lys305 310 315 320Asn Ile Asn Ile Ser Asn Asn His Phe

325(2) SEQ ID NO 875 information

Sequence properties:

(A) length: 146 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...146

(xi) sequence representation: 875 SEQ ID NO: Met Arg Leu Leu Phe Leu Leu Leu Ser Ala Thr Leu Met Leu Leu Ala 151015 Glu Glu Lys Ile Pro Leu Ser Asp Asp Ala Pro Ile Lys Leu Val His

20 25 30Trp Gln Asn Ala Leu Lys Glu Val Gln Pro Asp Ser Asn Ala Pro Ala

35 40 45Thr Pro Pro Ile Lys Ala Val Gln Thr Thr Leu Thr Phe Glu Thr Pro

50 55 60Phe Asn Lys Thr Pro Lys Ile Met Glu Val Glu Gly Gln Lys Val Ile65 70 75 80Val Leu Lys Asn Ala Gln Leu Asp Ser Lys Lys Thr Met Asp Phe Lys

85 90 95Glu Ala Ser Leu Asn Ala Leu Glu Met Phe Ser Tyr Gln Asn Asp Ile100 105 110Tyr Leu Leu Ser Lys Lys Ala Lys Ala Gly Leu Glu Ile Gln Ala Ser

115 120 125Ser Ser Lys Asp Lys Lys Gln Leu Ala Phe Phe Phe Tyr Pro Lys Val

130135140 Phe Ile145(2) information SEQ ID NO:876

Sequence properties:

(A) length: 660 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...660

(xi) sequence representation: 876: Met Leu Lys Lys Ile Phe Tyr Gly Phe Ile Val Leu Phe Leu Ile Ile 151015 Val Gly Leu Leu Ala Val Leu Val Ala Gln Val Trp Val Thr Thr Asp SEQ ID NO

20 25 30Lys Asp Ile Ala Lys Ile Lys Asp Tyr Arg Pro Ser Val Ala Ser Gln

35 40 45Ile Leu Asp Arg Lys Gly Arg Leu Ile Ala Asn Ile Tyr Asp Lys Glu

50 55 60Phe Arg Phe Tyr Ala Arg Phe Glu Glu Ile Pro Pro Arg Phe Val Glu65 70 75 80Ser Leu Leu Ala Val Glu Asp Thr Leu Phe Phe Glu His Gly Gly Ile

85 90 95Asn Leu Asp Ala Val Met Arg Ala Met Ile Lys Asn Ala Lys Ser Gly

100 105 110Arg Tyr Thr Glu Gly Gly Ser Thr Leu Thr Gln Gln Leu Val Lys Asn

115 120 125Met Val Leu Thr Arg Glu Lys Thr Leu Thr Arg Lys Leu Lys Glu Ala

130 135 140Ile Ile Ser Ile Arg Ile Glu Lys Val Leu Ser Lys Glu Glu Ile Leu145 150 155 160Glu Arg Tyr Leu Asn Gln Thr Phe Phe Gly His Gly Tyr Tyr Gly Val

165 170 175Lys Thr Ala Ser Leu Gly Tyr Phe Lys Lys Pro Leu Asp Lys Leu Thr

180 185 190Leu Lys Glu Ile Thr Met Leu Val Ala Leu Pro Arg Ala Pro Ser Phe

195 200 205Tyr Asp Pro Thr Lys Asn Leu Glu Phe Ser Leu Ser Arg Ala Asn Asp

210 215 220Ile Leu Arg Arg Leu Tyr Ser Leu Gly Trp Ile Ser Ser Asn Glu Leu225 230 235 240Lys Ser Ala Leu Asn Glu Val Pro Ile Val Tyr Asn Gln Thr Ser Thr

245 250 255Gln Asn Ile Ala Pro Tyr Val Val Asp Glu Val Leu Lys Gln Leu Asp

260 265 270Gln Leu Asp Gly Leu Lys Thr Gln Gly Tyr Thr Ile Lys Leu Thr Ile

275 280 285Asp Leu Asp Tyr Gln Arg Leu Ala Leu Glu Ser Leu Arg Phe Gly His

290 295 300Gln Lys Ile Leu Glu Lys Ile Ala Lys Glu Lys Pro Lys Thr Asn Ala305 310 315 320Ser Asn Asp Lys Asp Glu Asp Asn Leu Asn Ala Ser Met Ile Val Thr

325 330 335Glu Thr Ser Thr Gly Lys Ile Leu Ala Leu Val Gly Gly Ile Asp Tyr

340 345 350Lys Lys Ser Ala Phe Asn Arg Ala Thr Gln Ala Lys Arg Gln Phe Gly

355 360 365Ser Ala Ile Lys Pro Phe Val Tyr Gln Ile Ala Phe Asp Asn Gly Tyr

370 375 380Ser Thr Thr Ser Lys Ile Pro Asp Thr Ala Arg Asn Phe Glu Asn Gly385 390 395 400Asn Tyr Ser Lys Asn Ser Val Gln Asn His Ala Trp His Pro Ser Asn

405 410 415Tyr Thr Arg Lys Phe Leu Gly Leu Val Thr Leu Gln Glu Ala Leu Ser

420 425 430His Ser Leu Asn Leu Ala Thr Ile Asn Leu Ser Asp Gln Leu Gly Phe

435 440 445Glu Lys Ile Tyr Gln Ser Leu Ser Asp Met Gly Phe Lys Asn Leu Pro

450 455 460Lys Asp Leu Ser Ile Val Leu Gly Ser Phe Ala Ile Ser Pro Ile Asp465 470 475 480Ala Ala Glu Lys Tyr Ser Leu Phe Ser Asn Tyr Gly Thr Met Leu Lys

485 490 495Pro Met Leu Ile Glu Ser Ile Thr Asn Gln Gln Asn Glu Val Lys Thr

500 505 510Phe Thr Pro Ile Glu Thr Lys Lys Ile Thr Ser Lys Glu Gln Ala Phe

515 520 525Leu Thr Leu Ser Ala Leu Met Asp Ala Val Glu Asn Gly Thr Gly Ser

530 535 540Leu Ala Arg Ile Lys Gly Leu Glu Ile Ala Gly Lys Thr Gly Thr Ser545 550 555 560Asn Asn Asn Ile Asp Ala Trp Phe Ile Gly Phe Thr Pro Thr LeuGln

565 570 575Ser Val Ile Trp Phe Gly Arg Asp Asp Asn Thr Pro Ile Gly Lys Gly

580 585 590Ala Thr Gly Gly Val Val Ser Ala Pro Val Tyr Ser Tyr Phe Met Arg

595 600 605Asn Ile Leu Ala Ile Glu Pro Ser Leu Lys Arg Lys Phe Asp Val Pro

610 615 620Lys Gly Leu Arg Lys Glu Ile Val Asp Lys Ile Pro Tyr Tyr Ser Ser625 630 635 640Pro Asn Ser Ile Thr Pro Thr Pro Lys Lys Thr Asp Asp Ser Glu Glu

645 650 655Arg Leu Leu Phe

660(2) SEQ ID NO 877 message

Sequence properties:

(A) length: 113 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...113

(xi) sequence representation: 877: Met Ala Lys Met Asn Ala Pro Asp Gly Val Ala Val Trp Val Asn Glu 151015 Asp Arg Cys Lys Gly Cys Asp Ile Cys Val Ser Val Cys Pro Ala Gly SEQ ID NO

20 25 30Val Leu Gly Met Gly Ile Glu Lys Glu Arg Val Leu Gly Lys Val Ala

3540 45Lys Val Ala Tyr Pro Glu Ser Cys Ile Gly Cys Val Gln Cys Glu Leu

50 55 60His Cys Pro Asp Phe Ala Ile Tyr Val Ala Asp Arg Lys Asp Phe Lys65 70 75 80Phe Ala Lys Val Ser Lys Glu Ala Gln Glu Arg Ser Glu Lys Val Lys

85 90 95Ala Asn Lys Tyr Met Leu Leu Glu Glu Thr Ile Leu Glu Gly Arg Gly

100105110 Lys (2) SEQ ID NO:878 message

Sequence properties:

(A) length: 339 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...339

(xi) sequence representation: 878: Met Ile Phe Ile Asp Ala Cys Phe ArG Lys Glu Thr Pro Tyr Thr Pro 151015 Ile Trp Met Met Arg Gln Ala Gly Arg Tyr Leu Ser Glu Tyr Gln Glu SEQ ID NO

20 25 30Ser Arg Lys Lys Ala Gly Ser Phe Leu Glu Leu Cys Lys Asn Ser Asp

35 40 45Leu Ala Thr Glu Val Thr Leu Gln Pro Val Glu Ile Leu Gly Val Asp

50 55 60Ala Ala Ile Leu Phe Ser Asp Ile Leu Val Val Pro Leu Glu Met Gly65 70 7580Leu Asn Leu Glu Phe Ile Pro Lys Lys Gly Pro His Phe Leu Glu Thr

85 90 95Ile Thr Asp Leu Lys Ser Val Glu Ser Leu Lys Val Gly Val Tyr Lys

100 105 110Gln Leu Asn Tyr Val Tyr Asp Thr Ile Ser Gln Thr Arg Gln Lys Leu

115 120 125Ser Lys Glu Lys Ala Leu Ile Gly Phe Cys Gly Ser Pro Trp Thr Leu

130 135 140Ala Thr Tyr Met Ile Glu Gly Glu Gly Ser Lys Ser Tyr Ala Lys Ser145 150 155 160Lys Lys Met Leu Tyr Ser Glu Pro Glu Val Leu Lys Ala Leu Leu Glu

165 170 I75Lys Leu Ser Leu Glu Leu Ile Glu Tyr Leu Ser Leu Gln Ile Gln Ala

180 185 190Gly Val Asn Ala Val Met Ile Phe Asp Ser Trp Ala Ser Ala Leu Glu

195 200 205Lys Glu Ala Tyr Leu Glu Phe Ser Trp Asp Tlr Leu Lys Lys Ile Ser

210 215 220Lys Glu Leu Lys Lys Arg Tyr Ala His Ile Pro Val Ile Leu Phe Pro225 230 235 240Lys Gly Ile Gly Ala Tyr Leu Asp Ser Ile Asp Gly Glu Phe Asp Val

245 250 255Phe Gly Val Asp Trp Gly Thr Pro Leu Thr Ala Ala Lys Lys Ile Leu

260 265 270Gly Gly Lys Tyr Val Leu Gln Gly Asn Leu Glu Pro Thr Arg Leu Tyr

275 280 285Asp Lys Asn Ala Leu Glu Glu Gly Val Glu Lys Ile Leu Lys Val Met

290 295 300Gly Asn Gln Gly His Ile Phe Asn Leu Gly His Gly Met Leu Pro Asp305 310 315 320Leu Pro Arg Glu Asn Ala Lys Tyr Leu Val Gln Leu Val His Ala Lys

325330335 Thr Arg Arg (2) SEQ ID NO:879 message

Sequence properties:

(A) length: 192 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...192

(xi) sequence representation: 879: Val Leu Glu Lys Ser Phe Leu Lys Ser Lys Gln Leu Val Leu Cys Gly 151015 Leu Gly Val Leu Met Leu Gln Ala Cys Thr Cys Pro Asn Thr Ser Gln SEQ ID NO

20 25 30Arg Asn Ser Phe Leu Gln Asp Val Pro Tyr Trp Met Leu Gln Asn Arg

35 40 45Ser Gln Tyr Leu Thr Gln Gly Val Asp Ser Ser His Ile Val Asp Gly

50 55 60Lys Ala Thr Glu Glu Ile Glu Lys Ile Ala Thr Lys Arg Ala Thr Ile65 70 75 80Arg Val Ala Gln Asn Ile Val His Lys Leu Lys Glu Ala Tyr Leu Ser

85 90 95Lys Ser Asn Arg Ile Lys Gln Lys Ile Thr Asn Glu Met Phe Ile Gln

100 105110Men Thr Lys Pro Ile Phe Asp Ser Leu Met Asn Val Asp Arg Leu Gly

115 120 125Ile Tyr Ile Asn Pro Asn Asn Glu Glu Val Phe Ala Leu Val Arg Ala

130 135 140Arg Ser Phe Asp Lys Asp Ala Leu Ser Glu Gly Leu His Lys Met Ser145 150 155 160Leu Asp Asp Gln Ala Val Ser Ile Leu Val Ser Lys Val Glu Glu Ile

165 170 175Phe Lys Asp Ser Ile Asn Tyr Gly Asp Val Lys Val Pro Ile Ala Met

180185190 (2) SEQ ID NO 880 information

Sequence properties:

(A) length: 110 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...110

(xi) sequence representation: SEQ ID NO 880: Met Leu Arg Asn Gln Phe Arg Ile Val Phe Val Ser Cys Ile Val Ala 151015 Ser Ser Leu Gln Ala Gln Glu Asn Thr His Thr Leu Gly Lys Val Thr

20 25 30Thr Lys Gly Glu Arg Thr Phe Glu Tyr Asn Asn Lys Met Tyr Ile Asp

35 40 45Arg Lys Glu Leu Gln Gln Arg GLn Ser Asn Gln Ile Arg Asp Ile Phe

50 5560Arg Thr Arg Ala Asp Val Asn Val Ala Ser Gly Gly Leu Met Ala Gln55 70 75 80Lys Ile Tyr Val Arg Gly Ile Glu Ser Arg Leu Leu Arg Val Thr Ile

85 90 95Asp Gly Val Ala Gln Asn Gly Asn Ile Phe His His Asp Ala

100105110 (2) SEQ ID NO 881 information

Sequence properties:

(A) length: 89 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...89

(xi) sequence representation: SEQ ID NO 881 Val Met Lys Lys Ile Val Val Ser Leu Cys Val Ala Leu Gly Phe Leu 151015 Ser Ala Asp Pro Ala Gln Ala Asn Lys Ala Ile Ser Asp Ala Asp Leu

20 25 30Ile Glu Glu Ile Arg Asp Leu Lys Lys Ile Ile Ser Ala Gln Asn Thr

35 40 45Glu Ile Asn Gln Leu Arg Lys Val Gln Glu Val Leu Ser Gly Gln Leu

50 55 60Gly Asp Met Arg Lys Asp Ile Leu Ser Thr Arg Asp Tyr Cys Ile Ser65 70 75 80Leu Arg Pro Tyr Ile Tyr Asn Trp Arg

85(2) SEQ ID NO 882 information

Sequence properties:

(A) length: 158 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...158

(xi) sequence representation: 882 SEQ ID NO: Leu Asn Lys Phe Gly Trp Arg Ala Cys Phe Leu Thr Leu Phe Phe Ser 151015 Gly Tyr Ser Lys Lys Ala Pro Gly Thr Ile Gly Ser Leu Val Ala Leu

20 25 30Leu Leu Gly Leu Pro Ile Leu Ile Phe Ser Ala Asn Thr Leu Phe Leu

35 40 45Gly Ala Ile Phe Val Gly Leu Ile Ala Ile Thr Gln Ile Asp Lys Glu

50 55 60Glu Glu Glu Thr Lys Arg His Asp Ser Ser Tyr Ile Val Ile Asp Glu65 70 75 80Leu Va1 Gly Met Trp Leu Ala Met Ala Ile Ser Gly Leu Ser Leu Val

85 90 95Gly Val Ile Leu Ser Phe Ile Phe Phe Arg Ile Tyr Asp Ile Thr Lys

100 105 1l0Pro Ser Leu Ile Gly Lys Ile Asp Lys Glu Val Lys Gly Gly Leu Gly

115 120 125Val Val Ala Asp Asp Ala Leu Ala Gly Val Leu Ala Gly Leu Ser Thr

130135140 Leu Leu Ala Ile Asn Ile Leu Gly Phe Phe Asn Ile Lys Phe 145150155 (2) SEQ ID NO 883 information

Sequence properties:

(A) length: 133 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...133

(xi) sequence representation: 883: Met Glu Leu Ile Lys Lys Leu Glu Lys Glu Ser Glu Val Leu Lys Lys 151015 Asp Leu Gln Gln His Ser Asn Glu Leu Phe Lys Met Leu Ile Ile Asp SEQ ID NO

20 25 30Asn Glu Asp Leu Phe Lys Glu Gln Phe Glu Ile Met Phe Lys Ala Trp

35 40 45Val Glu Ile Val Lys Met Met Phe Glu Leu Thr Lys Lys Thr Lys Phe

50 55 60Asp Gly Glu Met Ile Gly Tyr Thr Glu Glu Leu Leu Thr Phe Leu Val65 70 75 80Arg Asp Phe Phe Asn Gly Ile Phe Lys Ser Lys Val Ile Pro Lys Met

85 90 95Pro Ile Phe Cys Gly Asp Val Lys Cys Glu Asp Phe Asn Ala Leu Arg

100 105 1l0Ser Leu Val Tyr Leu Ser Val Leu Glu Leu Glu Glu Thr Ile Asn Pro

115 120 125Asn Lys Ile Pro Phe

130(2) SEQ ID NO 884 message

Sequence properties:

(A) length: 133 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...133

(xi) sequence representation: 884: Met Glu Leu Ile Lys Lys Leu Glu Lys Glu Ser Glu Val Leu Lys Lys 151015 Asp Leu Gln Gln His Ser Asn Glu Leu Phe Lys Met Leu Ile Ile Asp SEQ ID NO

20 25 30Asn Glu Asp Leu Phe Lys Glu Gln Phe Glu I1e Met Phe Lys Ala Trp

35 40 45Val Glu Ile Val Lys Met Met Phe Glu Leu Thr Lys Lys Thr Lys Phe

50 55 60Asp Gly Glu Met Ile Gly Tyr Thr Glu Glu Leu Leu Thr Phe Leu Val65 70 75 80Arg Asp Phe Phe Asn Gly Ile Phe Lys Ser Lys Val Ile Pro Lys Met

85 90 95Pro Ile Phe Cys Gly Asp Val Lys Cys Glu Asp Phe Asn Ala Leu Arg

100 105 110Ser Leu Val Tyr Leu Ser Val Leu Glu Leu Glu Glu Thr Ile Asn Pro

115 120 125Asn Lys Ile Pro Phe

130(2) SEQ ID NO 885 message

Sequence properties:

(A) length: 125 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...125

(xi) sequence representation: 885: Met Lys Lys Leu Ala Ala Leu Phe Leu Val Ser Ala Leu Gly Val Met 151015 Ser Leu Asn Ala Trp Glu Gln Thr Leu Lys Ala Asn Asp Leu Glu Val SEQ ID NO

20 25 30Lys Ile Lys Ser Val Gly Asn Pro Ile Lys Gly Asp Asn Thr Phe Val

35 40 45Leu Ser Pro Thr Leu Lys Gly Lys Ala Leu Glu Lys Ala Ile Val Arg

50 55 60Val Gln Phe Met Met Pro Glu Met Pro Gly Met Pro Ala Met Lys Glu65 70 75 80Met Ala Gln Val Ser Glu Lys Asn Gly Leu Tyr Glu Ala Lys Thr Asn

85 90 95Leu Ser Met Asn Gly Thr Trp Gln Val Arg Val Asp Ile Lys Ser Lys

100 105 110Glu Gly Gln Val Tyr Arg Thr Lys Thr Ser Leu Asp Leu

115120125 (2) SEQ ID NO 886 message

Sequence properties:

(A) length: 341 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...341

(xi) sequence representation: 886: Met Lys Arg Leu Leu Leu Leu Ala Leu Ala Leu Phe Phe Ser Leu Ser 151015 Cys Thr Asn Ala Gln Glu Ile Lys Glu Thr Gln Glu Thr Lys Lys Thr SEQ ID NO

20 25 30Lys Glu Thr Lys Ser Gln Thr Arg Phe Asn Ile Ser Thr Thr Lys Val

35 40 45Ile Glu Lys Glu Phe Ser Gln Ser Arg Arg Tyr Tyr Ala Leu Leu Glu

50 55 60Pro Asn Glu Ala Leu Ile Phe Ser Gln Thr Leu Arg Phe Asp Gly Tyr65 70 75 80Val Glu Lys Leu Tyr Ala Asn Lys Thr Tyr Thr Pro Ile Lys Lys Gly

85 90 95Asp Arg Leu Leu Ser Val Tyr Ser Pro Glu Leu Ala Glv Val Gln Ser100 105 110Glu Leu Leu Ser Ser Leu Lys Phe Asn Gln Gln Val Gly Ala Ile Lys

115 120 125Glu Lys Leu Lys Leu Leu Gly Leu Glu Asn Phe Ser Ile Glu Lys Ile

130 135 140Ile Ser Ser His Lys Val Gln Asn Glu Ile Thr Ile Tyr Ser Arg Phe145 150 155 160Asn Gly Val Ile Phe Lys Lys Ser Pro Asp Leu Asn Glu Gly Ser Phe

165 170 175Ile Lys Lys Gly Gln Glu Leu Phe Lys Ile IleAsp Leu Ser Arg Leu

180 185 190Trp Ala Leu Val Lys Val Ash Gln Glu Asp Leu Glu Phe Leu Lys Asn

195 200 205Thr His Gln Ala Ile Leu Phe Val Glu Gly Val Lys Gly Lys Gln Ala

210 215 220Ile Thr Leu Glu Asn Ile Asn Pro Ile Ile Asn Ala Gln Asp Lys Met225 230 235 240Leu Glu Ala Arg Phe Asn Val Pro Asn Leu Lys Leu Leu Tyr Tyr Pro

245 250 255Asn Met Phe Ala Gln Val Glu Ile Phe His Lys Pro Gln Lys Met Lys

260 265 270Ile Leu Pro Lys Glu AIa Val Leu Ile Lys Gly Gly Lys Ala Ile Val

275 280 285Phe Lys Lys Asp Asp Phe Gly Leu Ser Pro Leu Glu Ile Lys Ala Val

290 295 300Arg Leu Ser Asp Gly Ser Tyr Glu Ile Leu Glu Gly Leu Lys Ala Gly305 310 315 320Glu Glu Val Ala Asn Asn Ala Leu Phe Val Leu Asp Ala Asp Ala Gln

325 330 335Asn Asn Gly Asp Tyr

340(2) SEQ ID NO 887 message

Sequence properties:

(A) length: 120 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...120

(xi) sequence representation: 887: Met Gly Val Ala Val Val Leu Phe Leu Thr Leu Ile Leu Leu Phe Leu 151015 Val Leu Arg Asp Phe Gly Leu Ala Ser Pro Lys Gln Lys Ile Leu Ala SEQ ID NO

20 25 30Phe Leu Ile Val Gly Ile Ile Gly Ala Ser Ile Ser Val Tyr Thr Tyr

35 40 45Lys Gln Asn Gln Gln Asn Gln Gln Glu Ile Ala Leu Gln Arg Ala Phe

50 55 60Leu Arg Gly Glu Thr Leu Leu Cys Lys Gly Ile Lys Val Asn Asn Gln65 70 75 80Thr Phe Asn Leu Val Ser Gly Thr Leu Ser Phe Leu Gly Lys Lys Gln

85 90 95Thr Pro Met Lys Asp Val Leu Val Asp Leu Asp Ser Cys Gln Thr Leu

100 105 I10Gln Lys Asp Pro Leu Ile Gln Pro

115120 (2) the information of SEQ ID NO 888

Sequence properties:

(A) length: 332 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...332

(xi) sequence representation: 888, Met Arg Phe Phe Ile Leu Phe Phe Met Gly Met Leu Gly Val Gly Phe 151015,151015, Gln Thr Glu Leu Asp Leu Lys Asp Leu Glu Lys Lys Pro Ala Gly SEQ ID NO

20 25 30Ile Val Arg Asp Tyr Tyr Leu Trp Arg Tyr Ile Ser Asp Lys Lys Thr

35 40 45Ser Leu Glu Asn Ala Lys Lys Ala Tyr Glu Leu Thr Gln Asn Lys Asn

50 55 60Ser Ala Leu Gln Lys Ala Met Gln Glu Lys Gly Val Glu Asn Ser Asp65 70 75 80Lys Ser Pro Asp Ala Lys Met Pro Glu Asp Ile Tyr Cys Lys Gln Ile

85 90 95Thr Leu Glu Ser Met Leu Glu Thr Thr Asp Ala Phe Gln Ala Ser Cys

100 105 110Ile Ala Ile Ala Leu Lys Ser Lys Ile Arg Asp Phe Asp Lys Ile Pro

115 120 125Ile Gln Thr Phe Lys Pro Leu Gln Glu Lys Ile Lys Glu Ala Tyr Pro

130 135 140Ile Leu Tyr Glu Glu Leu Glu Ile Leu Gln Ser Lys Asn Val Ser Ala145 150 155 160Ser Leu Phe Lys Ala Asn Ala Gln Val Phe Ser Ala Leu Phe Asn His165 170 175Leu Ser Tyr Glu Lys Lys Leu Gln Ile Phe Glu Lys His Ile Pro Ile

180 l85 190Lys Glu Leu Asn Arg Leu Leu Asp Glu Asp Tyr Pro Ala Phe Asn Arg

l95 200 205Leu Ile Tyr Gln Val Ile Leu Asp Pro Lys Leu Asp His Phe Lys Asp

210 215 220Ala Leu Ala Lys Ser Asn Ala Thr Gln Ser AsnAla Gln Thr Phe Phe225 230 235 240Ile Leu Gly Ile Asn Glu Ile Leu His Lys Lys Thr Ser Lys Ala Leu

245 250 255Lys Tyr Phe Glu Arg Ser Glu Ala Val Val Lys Asp Asp Asp Phe Ser

260 265 270Lys Asp Arg Ala Ile Phe Trp Gln Tyr Leu Ala Ser Lys Lys Lys Lys

275 280 285Thr Leu Glu His Leu Ser Gln Ser Pro Ala Leu Asn Leu Tyr Ser Leu

290 295 300Tyr Ala Ser Arg Lys Pro Gln Asn His Ala Gln Leu Ser His His Phe305 310 315 320Ser Tyr Pro Lys Phe Lys Pro Arg Glu Pro Ser Phe

325330 (2) information SEQ ID NO 889

Sequence properties:

(A) length: 157 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...157

(xi) sequence representation: 889: Val His Leu Ala His Tyr Leu Lys Arg Asn Phe Ser Phe Phe Pro Ser 151015 Val Asp Ile Val Asp Gly Gly Thr Met Ala Gln Gln Leu Ile Pro Leu SEQ ID NO

20 25 30Ile Thr Ser Tyr Glu Lys Val Leu Ile Leu Asp Cys Val Ser Ala Lys

3540 45Gly Val Glu Ile Gly Ser Val Tyr Ala Phe Asp Phe Lys Asp Ala Pro

50 55 60Lys Glu Ile Thr Trp Ala Gly Ser Ala His Glu Val Glu Met Leu His65 70 75 80Thr Leu Arg Leu Thr Glu Phe Leu Gly Asp Leu Pro Lys Thr Phe Ile

85 90 95Val Gly Leu Val Pro Phe Val Ile Gly Ser Glu Thr Thr Phe Lys Leu

100 105 110Ser Ser Glu Met Leu Asn Ala Leu Glu Thr Ala Leu Lys Ala Ile Glu

115 120 125Thr Gln Leu Asn Ala Trp Gly Val Lys Met Gln Arg Thr Asp HIs Ile

130135140 Ala Leu Asp Cys Ile Ala Glu Leu Ser Tyr Lys Gly Phe 145150155 (2) SEQ ID NO:890 information

Sequence properties:

(A) length: 307 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...307

(xi) sequence representation: SEQ ID NO 890: Met Lys Lys Val Leu Leu Leu Thr Leu Ser Leu Ser Leu Ser Phe Trp 151015 Leu His Ala Glu Arg Asn Gly Phe Tyr Leu Gly Leu Asn Phe Ala Glu

20 25 30Gly Ser Tyr Ile Gln Gly Gln Gly Ser Ile Gly Glu Lys Ala Ser Ala

35 40 45Glu Asn Ala Leu Asn Gln Ala Ile Ash Asn Ala Lys Asn Ser Leu Phe

50 55 60Pro Asn Thr Lys Ala Ile Arg Asp Val Gln Asn Ala Leu Asn Ala Val65 70 75 80Lys Asp Ser Asn Lys Ile Ala Asn Arg Phe Ala Gly Asn Gly Gly Ser

85 90 95Gly Gly Ile Phe Asn Glu Leu Ser Leu Gly Tyr Lys Tyr Phe Leu Gly

100 105 110Lys Lys Arg Ile Ile Gly Phe Arg His Ser Leu Phe Phe Gly Tyr Gln

115 120 125Leu Gly Gly Val Gly Ser Val Pro Gly Ser Gly Leu Ile Ala Phe Leu

130 135 140Pro Tyr Gly Phe Asn Thr Asp Leu Leu Ile Asn Trp Thr Asn Asp Lys145 150 155 160Arg Ala Ser Gln Glu Tyr Val Glu Arg Arg Val Lys Gly Leu Ser Ile

165 170 175Phe Tyr Lys Asp Met Thr Gly Arg Thr Leu Asp Ala Asp Thr Leu Lys

180 185 190Arg Ala Ser Arg His Ile Ile Arg Lys Ser Ser Gly Leu Val Ile Gly

195 200 205Met Glu Leu Gly Ala Ser Thr Trp Phe Ala Ser Asn Asn Leu Thr Pro

210 215 220Phe Asn Gln Val Lys Ser Arg Thr Ile Phe Gln Leu Gln Gly Lys Phe225 230 235 240Gly Val Arg Phe Ser Ser Asp Glu Tyr Asp Ile Asp Arg Tyr Gly Asp

245 250 255Glu Asn Tyr Leu Gly Gly Ser Ser Val Glu Leu Gly Val Lys Val Pro

260 265 270Ala Phe Lys Val Asn Tyr Tyr Ser Asp Asp Tyr Gly Asp Lys Leu Asp

275 280 285Tyr Lys Arg Val Val Ser Val Tyr Leu Asn Tyr Thr Tyr Asn Phe Lys

290295300 Asn Lys His305(2) SEQ ID NO:891 information

Sequence properties:

(A) length: 578 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...578

(xi) sequence representation: 891: Met Ser Lys Lys Ile Val Val Asp Pro Ile Thr Arg Ile Glu Gly His 151015 Leu Arg Ile Glu Val Ile Val Asp Asp Asp Asn Val Ile Thr Asp Ala SEQ ID NO

20 25 30Phe Ser Ser Ser Thr Leu Phe Arg Gly Leu Glu Thr Ile Ile Lys Gly

35 40 45Arg Asp Pro Arg Asp Ala Gly Phe Ile Ala Gln Arg Ile Cys Gly Val

50 55 60Cys Thr Tyr Ser His Tyr Lys Ala Gly Val Thr Ala Val Glu Asn Ala65 70 75 80Leu Gly Ile Thr Pro Pro Leu Asn Ala Gln Leu Val Arg Ser Leu Met

85 90 95Asn Met Ala Leu Leu Phe His Asp His Val Val His Phe Tyr ThrLeu

100 105 110His Gly Leu Asp Trp Cys Asp Ile Leu Ser Thr Leu Lys Ala Asp Pro

115 120 125Ile Gln Ala Ala Lys Leu Ser Phe Lys Tyr Ser Pro Tyr Pro Ile Asn

130 135 140Thr Gly Ala Gly Glu Leu Lys Ala Val Gln Lys Arg Leu Asn Asp Phe145 150 155 160Ala Lys Ser Gly Ser Leu Gly Pro Phe Ser Asn Gly Tyr Tyr Gly His

165 170 175Lys Thr Tyr Arg Leu Asn Pro Glu Gln Asn Leu Ile Val Leu Ser His

180 185 190Tyr Leu Lys Leu Leu Glu Ile Gln Arg Glu Ala Ala Lys Met Thr Ala

195 200 205Ile Phe Gly Ala Lys Gln Pro His Pro Gln Ser Leu Thr Val Gly Gly

210 215 220Val Thr Ser Val Met Asp Ile Leu Asp Pro Thr Arg Leu Ala Glu Trp225 230 235 240Lys Ser Lys Phe Glu Val Val Ala Asn Phe Ile Asn His Ala Tyr Tyr

245 250 255Pro Asp Leu Val Met Ala Gly Glu Met Phe Ala Asn Glu Pro Ser Val

260 265 270Ile Lys Gly Cys Gly Leu Arg Asn Phe Ile Ala Tyr Glu Glu Val Leu

275 280 285Leu Gly Lys Asp Lys Tyr Leu Leu Ser Ser Gly Val Val Leu Asp Gly

290 295 300Asp Ile Ser Lys Leu His Pro Ile Asp Glu Ser Leu Ile Lys Glu Glu305 310 315 320Val Thr His Ser Trp Tyr Gln Tyr Glu Asp Thr LysGlu Val Gln Leu

325 330 335His Pro Tyr Asp Gly Gln Thr Asn Pro His Tyr Thr Gly Leu Lys Asp

340 345 350Gly Glu Ser Val Gly Ile Glu Asn Lys Ile Ile Pro Ala Lys Val Leu

355 360 365Asp Thr Lys Asp Lys Tyr Ser Trp Ile Lys Ser Pro Arg Tyr Asp Ser

370 375 380Lys Pro Met Glu Val Gly Pro Leu Ser Ser Val Val Val Gly Leu Ala385 390 395 400Ala Lys Asn Pro Tyr Val Thr Glu Val Ala Thr Lys Phe Leu Lys Asp

405 410 415Thr Lys Leu Pro Leu Glu Ala Leu Phe Ser Thr Leu Gly Arg Thr Ala

420 425 430Ala Arg Cys Ile Glu Ala Lys Thr Ile Ala Asp Asn Gly Leu Leu Ala

435 440 445Phe Asp Ala Leu Val Glu Asn Leu Lys Ser Asp Gln Ser Thr Cys Ala

450 455 460Pro Tyr His Ile Asp Lys Asn Gln Glu Tyr Lys Gly Arg Tyr Ile Gly465 470 475 480Gln Val Pro Arg Gly Met Leu Ser His Trp Val Arg Ile Lys Asn Gly

485 490 495Val Val Glu Asn Tyr Gln Ala Val Val Pro Ser Thr Trp Asn Ala Gly

500 505 510Pro Arg Asp Ser Lys Asn Gln Arg Gly Ala Tyr Glu Met Ser Leu Ile

515 520 525Gly Thr Lys Ile Ala Asp Leu Thr Gln Pro Leu Glu Ile Ile Arg Thr

530 535 540Ile His Ser Phe Asp Pro Cys Ile Ala Cys SerVal His Val Met Asp545 550 555 560Phe Lys Gly Gln Ser Leu Asn Glu Phe Lys Val Glu Pro Asn Phe Ala

565570575 Lys Phe (2) SEQ ID NO:892 message

Sequence properties:

(A) length: 68 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...68

(xi) sequence representation: 892: Met Asn Ser Ser Asn Leu Lys Asn Trp Leu Phe Pro Thr Ile Cys Phe 151015 Phe Leu Phe Cys Tyr Ile Leu Ile Phe Leu Ile Phe Phe Met Phe Lys SEQ ID NO

20 25 30Asn Leu Gln Ser Gln Ser Phe Gly Ser Val Ala Glu Thr Gly Lys Lys

35 40 45Pro Ile Thr Thr Thr Lys Lys Phe Gly Lys Glu Leu Gln Lys Gln Ile

505560 Ser Lys Ile His65(2) SEQ ID NO 893 information

Sequence properties:

(A) length: 53 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...53

(xi) sequence representation: 893: Val Val Leu Pro Lys Glu Thr Leu Ser Ser Ile Ala Lys Arg Tyr Gln 151015 Val Ser Ile Ser Ser Ile Gln Leu Ala Asn Asn Leu Lys Asp Ser Asn SEQ ID NO

20 25 30Ile Phe Ile His Gln Arg Leu Ile Ile Pro Thr Asn Lys Lys Leu Leu

35 40 45Ala Thr Arg Glu Phe

50(2) information of SEQ ID NO 894

Sequence properties:

(A) length: 352 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...352

(xi) sequence representation: 894: leu Tyr Phe Leu Asn Gly Gly Tyr Asn Arg Leu His Lys Ser Tyr Glu 151015 Arg Ile Val Met Leu Ile Ala Arg Phe Lys Lys Ala Leu Ile Ser Tyr

20 25 30Ser Leu Gly Val Leu Leu Val Ser Ser Leu Leu Gly Val Ala Asn Ala

35 40 45Ser Asn Gln Glu Ile Gln Val Lys Asp Tyr Phe Gly Glu Gln Thr Ile

5055 60Lys Leu Pro Val Ser Lys Ile Ile Tyr Leu Gly Ser Phe Ala Glu Val65 70 75 80Pro Ala Met Phe Asn Thr Trp Asp Arg Val Val Gly Ile Ser Asp Tyr

85 90 95Ala Phe Lys Ser Asp Ile Val Lys Ala Thr Leu Lys Asp Pro Glu Arg

l00 105 110Ile Lys Pro Met Ser Ser Asp His Val Ala Ala Leu Asn Val Glu Leu

115 120 125Leu Lys Lys Leu Ser Pro Asp Leu Val Val Thr Phe Val Gly Asn Pro

130 135 140Lys Ala Val Glu His Ala Lys Lys Phe Gly Ile Ser Phe Leu Ser Phe145 150 155 160Gln Glu Lys Thr Ile Val Glu Val Met Glu Asp Ile Asp Ala Gln Ala

165 170 175Lys Ala Leu Glu Val Asp Ala Ser Lys Lys Leu Ala Lys Met Gln Glu

180 185 190Thr Leu Asp Phe Ile Lys Glu Arg Leu Lys Asn Val Lys Lys Lys Lys

195 200 205Gly Val Glu Leu Phe His Lys Ala Asn Lys Ile Ser Gly His Gln Ala

210 215 220Leu Asp Ser Asp Ile Leu Glu Lys Gly Gly Ile Asp Asn Phe Gly Leu225 230 235 240Lys Tyr Val Lys Phe Gly Aru Ala Asp Ile Ser Val Glu Lys Ile Val

245 250 255Lys Glu Asn Pro Glu Ile Ile Phe Ile Trp Trp Ile Ser Pro Leu Ser

260 265 270Pro Glu Asp Val Leu Asn Asn Pro Lys Phe Ser Thr Ile Lys Ala Ile

275 280 285Lys Asn Lys Gln Val Tyr Lys Leu Pro Thr Met Asp Ile Gly Gly Pro

290 295 300Arg Ala Pro Leu Ile Ser Leu Phe Ile Ala Leu Lys Ala His Pro Glu305 310 315 320Ala Phe Lys Gly Val Asp Ile Asn Ala Ile Ile Lys Asp Tyr Tyr Lys

325 330 335Val Val Phe Asp Leu Asn Asp Ala Glu Val Glu Pro Phe Leu Trp His

340345350 (2) information of SEQ ID NO:895

Sequence properties:

(A) length: 197 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...197

(xi) sequence representation: 895: Met Lys Cys Ser Ser Phe Thr Ser Asn Ser Val Leu Asn Phe Phe Val 151015 Val Leu Ser Phe Ile Thr Ile Gly Leu Val Phe Phe Phe Leu Arg Ser SEQ ID NO

20 25 30Gln Pro Thr Ser Val Val Ser Lys Glu Asn Ile Pro Lys Ile Glu Leu

35 40 45Glu Asn Phe Lys Ala Phe Gln Ile Asn Asp Lys Ile Leu Asp Leu Ser

50 55 60Ile Glu Gly Lys Lys Ala Leu Gln Tyr Asp Asp His Glu Ile Phe Phe65 70 75 80Asp Ser Lys Ile Lys Arg Tyr Asp Glu Asp Thr Ile Glu Ser Val Glu

85 90 95Ser Pro Glu Ala Lys Arg Gln Gln Asp Leu Tyr Phe Phe Pro Asn Gly

100 105 110ValThr Tyr Lys Arg Ser Asp Asp Ser Ser Phe Trp Ser Glu Thr Gly

115 120 125Ile Tyr Asn His Lys Glu Gln Asn Phe Lys Gly Lys Gly Arg Phe Ile

130 135 140Leu Thr Ser Lys Asp Ser Lys Val Glu Gly Leu Asp Ile Ser Tyr Ser145 150 155 160His Ala Leu Ala Ile Ile Glu Ala Gln Ser Ile Gln Ala Asn Leu Phe

165 170 175Leu Asp Glu Ile Lys Gln Ser Gln Lys Glu Lys Lys Lys Phe Pro Thr

180 185 190Phe Lys Gly Gly Phe

195(2) SEQ ID NO 896 message

Sequence properties:

(A) length: 185 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...185

(xi) sequence representation: 896: Met Arg Trp Trp Cys Phe Leu Val Cys Cys Leu Ser Val Leu Ser Val 151015 Met Asp Ala Lys Lys Leu Glu Asn Lys Gly Leu Lys Lys Glu Arg GluSEQ ID NO

20 25 30Leu Leu Glu Ile Thr Gly Asn Gln Phe Val Ala Asn Asp Lys Thr Lys

35 40 45Thr Ala Val Ile Gln Gly Asn Val Gln Ile Lys Lys Gly Lys Asp Arg

50 55 60Leu Phe Ala Asp Lys Val Ser Val Phe Leu Asn Asp Lys Arg Lys Pro65 70 75 80Glu Arg Tyr Glu Ala Thr Gly Asn Thr His Phe Asn Ile Phe Thr Glu

85 90 95Asp Asn Arg Glu Ile Ser Gly Ser Thr Asp Lys Leu Ile Tyr Asn Ala

100 105 110Leu Asn Gly Glu Tyr Lys Leu Leu Gln Asn Ala Val Val Arg Glu Val

115 120 125Gly Lys Ser Asn Val Ile Thr Gly Asp Glu Ile Ile Leu Asn Lys Thr

130 135 140Lys Gly Tyr Ala Asp Val Leu Gly Ser Ala Lys Arg Pro Ala Lys Phe145 150 155 160Val Phe Asp Met Glu Asp Ile Asn Glu Glu Asn Arg Lys Ala Lys Leu

165 170 175Lys Lys Lys Gly Ala Lys Glu Lys Pro

180185 (2) SEQ ID NO 897 information

Sequence properties:

(A) length: 211 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...211

(xi) sequence representation: 897: Leu Ile Gln Gln Asn Phe Lys Thr Leu Lys Glu Leu Tyr Met Leu Val 151015 Thr Lys Leu Ala Pro Asp Phe Lys Ala Pro Ala Val Leu Gly Asn Asn SEQ ID NO

20 25 30Glu Val Asp Glu His Phe Glu Leu Ser Lys Asn Leu Gly Lys Asn Gly

35 40 45Val Ile Leu Phe Phe Trp Pro Lys Asp Phe Thr Phe Val Cys Pro Thr

50 55 60Glu Ile Ile Ala Phe Asp Lys Arg Val Lys Asp Phe His Glu Lys Gly65 70 75 80Phe Asn Val Ile Gly Val Sar Ile Asp Ser Glu Gln Val His Phe Ala

85 90 95Trp Lys Asn Thr Pro Val Glu Lys Gly Gly Ile Gly Gln Val Ser Phe

100 105 110Pro Met Val Ala Asp Ile Thr Lys Ser Ile Ser Arg Asp Tyr Asp Val

115 120 125Leu Phe Glu Glu Ala Ile Ala Leu Arg Gly Ala Phe Leu Ile Asp Lys

130 135 140Ash Met Lys Val Arg His Ala Val Ile Asn Asp Leu Pro Leu Gly Arg145 150 155 160Asn Ala Asp Glu Met Leu Arg Met Val Asp Ala Leu Leu His Phe Glu

165 170 175Glu His Gly Glu Val Cys Pro Ala Gly Trp Arg Lys Gly Asp Lys Gly

180 185 190Met Lys Ala Thr His Gln Gly Val Ala Glu Tyr Leu Lys Glu Asn Ser

195200 205Ile Lys Leu

210(2) information of SEQ ID NO 898

Sequence properties:

(A) length: 196 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...196

(xi) sequence representation: 898: Val Pro Leu Trp Ile Met Val Val Gly Ala Ala Gly Ile Ala Leu Gly 151015: 151015 Leu Ser Leu Tyr Gly Pro Lys Leu Ile Lys Thr Val Gly Ser Glu Ile SEQ ID NO

20 25 30Thr Glu Leu Asp Lys Met Gln Ala Phe Cys Ile Ala Leu Ser Ala Val

35 40 45Ile Thr Val Leu Leu Ala Ser Gln Leu Gly Leu Pro Val Ser Ser Thr

50 55 60His Ile Val Val Gly Ala Val Phe Gly Val Gly Phe Leu Arg Glu Arg65 70 75 80Leu Arg Glu Gln Ser Arg Arg Arg Phe Ala Arg Ile Arg Asp Asn Ile

85 90 95Val Ala Ala His Phe Gly Glu Asp Leu Glu Glu Ile Glu Gly Phe Leu

100 105 ll0Glu Arg Phe Asp Lys Ala Asn Leu Lys Glu Lys Ser Leu Met Leu Glu

115 120 125Ser Leu Lys LysSer Lys Asn Thr Ala Ile Ala Leu Glu Leu Lys Lys

130 135 140Lys Glu Lys Lys Ser Leu Lys Lys Val Tyr Lys Glu Glu Val Ile Lys145 150 155 160Arg Ser Ile Leu Lys Lys Ile Val Thr Ala Trp Leu Val Thr Val Pro

165 170 175Val Ser Ala Leu Leu Gly Ala Leu Leu Phe Val Ala Leu Gly Phe Ile

180 185 190Glu Lys Tyr Phe

195(2) SEQ ID NO 899 message

Sequence properties:

(A) length: 174 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...174

(xi) sequence representation: 899: Met Ser Asn Ser Met Leu Asp Lys Asn Lys Ala Ile Leu Thr Gly Gly 151015 Gly Ala Leu Leu Leu Gly Leu Ile Val Leu Phe Tyr Leu Ala Tyr Arg SEQ ID NO

20 25 30Pro Lys Ala Glu Val Leu Gln Gly Phe Leu Glu Ala Arg Glu Tyr Ser

35 40 45Val Ser Ser Lys Val Pro Gly Arg Ile Glu Lys Val Phe Val Lys Lys

50 55 60Gly Asp Arg Ile Lys Lys Gly Asp Leu Val Phe Ser Ile Ser Ser Pro6570 75 80Glu Leu Glu Ala Lys Leu Ala Gln Ala Glu Ala G1y His Lys Ala Ala

85 90 95Lys Ala Val Ser Asp Glu Val Lys Arg Gly Ser Arg Asp Glu Thr Ile

100 105 110Asn Ser Ala Arg Asp Val Trp Gln Ala Ala Lys Ser Gln Ala Asn Leu

115 120 125Ala Lys Glu Thr Tyr Lys Arg Val Gln Asp Leu Tyr Asp Asn Gly Val

130 135 140Ala Ser Leu Gln Lys Arg Asp Glu Ala Tyr Ala Ala Met Lys Ala Pro145 150 155 160Asn Thr Thr Arg Ala Arg Leu Thr Lys Ser Ile Lys Trp Leu

165170 (2) SEQ ID NO 900 information

Sequence properties:

(A) length: 148 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...148

(xi) sequence representation: SEQ ID NO 900: Met Glu Phe Leu Ser Gly Tyr Phe Leu Trp Val Lys Ala Phe His Val 151015 Ile Ala Val Ile Ser Trp Met Ala Ala Leu Phe Tyr Leu Pro Arg Leu

20 25 30Phe Val Tyr His Ala Glu Asn Ala His Lys Lys Glu Phe Val Gly Val

35 40 45Val Gln Ile Gln Glu Lys Lys Leu Tyr Ser Phe Ile Ala Ser Pro Ala

50 55 60Met Gly Phe Thr Leu Ile Thr Gly Ile Leu Met Leu Leu Ile Ala Pro65 70 75 80Glu Met Phe Lys Ser Gly Gly Trp Leu His Ala Lys Leu Ala Leu Val

85 90 95Val Leu Leu Leu Ile Tyr His Phe Tyr Cys Lys Lys Cys Met Arg Glu

100 105 110Leu Glu Lys Asp Pro Thr Gly Lys Asn Ala Arg Phe Tyr Arg Val Phe

115 120 125Asn Glu Ile Pro Thr Ile Leu Met Ile Leu Ile Val Ile Leu Val Val

130135140 Val Lys Pro Phe145(2) SEQ ID NO 901 information

Sequence properties:

(A) length: 145 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...145

(xi) sequence representation: SEQ ID NO 901: Met Lys Pro Ile Phe Leu Leu lle Phe Leu Leu Leu Ala Ser Leu Ile 151013 Ala Arg Glu Lys Asp Ala Ser Ser Asn Leu Phe Asp Leu Ile Asp Lys

20 25 30Gly Ile Asn Arg Glu Gln Glu Leu Lys Glu Gln Glu Gln Lys Thr Arg

35 40 45Leu Lys Leu Ala Gln Ser Pro Leu Val Ala Leu Glu Ile Val Pro Gln

50 55 60Glu Thr Pro Tyr Leu Glu Trp Gln Gly Ala Arg Glu Ser Tyr Tyr Leu65 70 75 80Lys Val Ser Ala Val Val Glu Ser Val Val Ile Leu Lys Ile Asp Ile

85 90 95Asn Gln Gly Arg Ser Cys Ser Leu Tyr Pro Thr Pro Lys Ser Val Ser

100 105 110Leu Val Arg Asn Gln Ser Val Ala Tyr Glu Ile Leu Cys Glu Asn Gln

115 120 125Pro Leu Trp Ile Glu Val Ser Thr Asn Leu Gly Lys Arg Thr Phe Gln

130135140 Phe145(2) SEQ ID NO:902 information

Sequence properties:

(A) length: 257 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...257

(xi) sequence representation: 902: Met Ala Lys Lys Asn Lys Pro Thr Glu Cys Pro Ala Gly Glu Lys Trp 151015 Ala Val Pro Tyr Ala Asp Phe Leu Ser Leu Leu Leu Ala Leu Phe Ile SEQ ID NO

20 25 30Ala Leu Tyr Ala Ile Ser Ala Val Asn Lys Ser Lys Val Glu Ala Leu

35 40 45Lys Thr Glu Phe Ile Lys Ile Phe Asn Tyr Ala Pro Lys Pro Glu Ala

50 55 60Met Gln Pro Val Val Val Ile Pro Pro Asp Ser Gly Lys Glu Glu Glu65 70 75 80Gln Met Ala Ser Glu Ser Ser Lys Pro Ala Ser Gln Asn Thr Glu Thr

85 90 95Lys Ala Thr Ile Ala Arg Lys Gly Glu Gly Ser Val Leu Glu Gln Ile

100 105 110Asp Gln Gly Ser Val Leu Lys Leu Pro Ser Ser Leu Leu Phe Glu Asn

115 120 125Ala Thr Ser Asp Ala Ile Asn Gln Asp Met Met Leu Tyr Ile Glu Arg

130 135 140Ile Ala Lys Ile Ile Gln Lys Leu Pro Lys Arg Val His Ile Asn Val145 150 155 160Arg Gly Phe Thr Asp Asn Thr Pro Leu Asn Lys Thr Arg Phe Lys Ser

165 170 175His Tyr Glu Leu Ala Ala Asn Arg Ala Tyr Arg Val Met Lys Val Leu

180 185 190Ile Gln Tyr Gly Val Asp Pro Asn Gln Leu Ser Phe Ser Ser Tyr Gly

195 200 205Ser Thr Asn Pro Ile Ala Pro Asn Asp Ser Leu Glu Asn Arg Met Lys

210 215 220Asn Asn Arg Val Glu Ile Phe Phe Ser Thr Asp Ala Asn Asp Leu Ser225 230 235 240Lys Ile His Ser Ile Leu Asp Glu Glu Phe Asn Pro His Lys Gln Gln

245250255 Glu (2) SEQ ID NO:903 information

Sequence properties:

(A) length: 798 aminoacid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...798

(xi) sequence representation: 903: Met Arg Lys Val Ile Ile Met Asn Gly Tyr Leu Arg Val Lys Thr Pro 151015 Tyr Phe Leu Ala Ser Val Val Leu Thr Phe Trp Thr Phe Asn Ser Phe SEQ ID NO

20 25 30Met Ser Ala Lys Asp Lys His His Phe Leu Lys Lys Val Thr Thr Thr

35 40 45Glu Gln Lys Phe Ser Ser Ser Ala Pro Ile Ser Trp Gln Ser Glu Glu

50 55 60Val Arg Asn Ser Thr Ser Ser Arg Thr Val Ile Ser Asn Lys Glu Leu65 70 75 80Lys Lys Thr Gly Asn Leu Asn Ile Glu Asn Ala Leu Gln Asn Val Pro

85 90 95Gly Ile Gln Ile Arg Asp Ala Thr Gly Thr Gly Val Leu Pro Lys Ile

100 105 110Ser Val Arg Gly Phe Gly Gly Gly Gly Asn Gly His Ser Asn Thr Asn

115 120 125Met Ile Leu Val Asn Gly Ile Pro Ile Tyr Gly Ala Pro Tyr Ser Asn

130 135 140Ile Glu Leu Ala Ile Phe Pro Val Thr Phe Gln Ser Val Asp Arg Ile145 150 155160Asp Val Ile Lys Gly Gly Thr Ser Val Gln Tyr Gly Pro Asn Thr Phe

165 170 175Gly Gly Val Val Asn Val Ile Thr Lys Glu Ile Pro Lys Glu Trp Glu

180 185 190Asn Gln Ala Ala Glu Arg Ile Thr Phe Trp Gly Arg Ser Ser Asn Gly

195 200 205Asn Phe Val Asp Pro Lys Glu Lys Gly Lys Pro Leu Ala Gln Thr Leu

210 215 220Gly Asn Gln Met Leu Phe Asn Thr Tyr Gly Arg Thr Ala Gly Met Leu225 230 235 240Gly Lys Tyr Ile Gly Ile Ser Ala Gln Gly Asn Trp Ile Asn Gly Gln

245 250 255Gly Phe Arg Gln Asn Ser Pro Thr Lys Val Gln Asn Tyr Leu Leu Asp

260 265 270Ala Ile Tyr Lys Ile Asn Ala Thr Asn Thr Phe Lys Ala Tyr Tyr Gln

275 280 285Tyr Tyr Gln Tyr Asn Ser Tyr His Pro Gly Thr Leu Ser Ala Gln Asp

290 295 300Tyr Ala Tyr Asn Arg Phe Ile Asn Glu Arg Pro Asp Asn Gln Asp Gly305 310 315 320Gly Arg Ala Lys Arg Phe Gly Ile Val Tyr Gln Asn Tyr Phe Gly Asp

325 330 335Pro Asp Arg Lys Val Gly Gly Asp Phe Lys Phe Thr Tyr Phe Thr His

340 345 350Asp Met Ser Arg Asp Phe Gly Phe Ser Asn Gln Tyr Gln Ser Val Tyr

355 360 365Met Ser Gly Gln Asn Lys Ile Leu Pro Phe Lys Gly Lys Gly Glu Ile

370 375380Ser Ala Lys Asn Pro Asn Cys Gly Leu Tyr Ser Tyr Ser Asp Thr Asn385 390 395 400Ser Pro Cys Trp Gln Phe Phe Asp Asn Ile Arg Arg Ser Val Val Asn

405 410 415Ala Phe Glu Pro Lys Leu Asn Leu Ile Val Asn Thr Gly Lys Val Lys

420 425 430Gln Thr Phe Asn Met Gly Met Arg Phe Leu Thr Glu Asp Leu Tyr Arg

435 440 445Arg Ser Thr Thr Arg Lys Asn Pro Ser Met Pro Asn Asn Gly Ser Gly

450 455 460Phe Asp Ala Gly Thr Ser Leu Asn Asn Phe Asn Asn Tyr Thr Ala Val465 470 475 480Tyr Ala Ser Asp Glu Ile Asn Phe Asn Asn Gly Met Leu Thr Ile Thr

485 490 495Pro Gly Leu Arg Tyr Thr Phe Leu Asn Tyr Glu Lys Lys Asp Ala Pro

500 505 510Pro Phe Lys Val Gly Gln Thr Pro Lys Thr Thr Lys Glu Arg Tyr Asn

515 520 525Gln Trp Asn Pro Ala Val Asn Val Gly Tyr Lys Pro Ile Lys Glu Leu

530 535 540Leu Phe Tyr Phe Asn Tyr Gln Arg Ser Tyr Ile Pro Pro Gln Phe Ser545 550 555 560Asn Ile Gly Asn Phe Val Gly Thr Ser Thr Asp Tyr Phe Gln I1e Phe

565 570 575Asn Val Met Glu Gly Gly Ser Arg Tyr Tyr Phe Asn His Gln Val Ser

580 585 590Phe Asn Ala Asn Tyr Phe Val Ile Phe Ala Asn His Tyr Phe Thr Gly

595600 605Arg Tyr Gly Asp Asn Arg Glu Pro Val Asn Ala Arg Ser Gln Gly Val

610 615 620Glu Leu Glu Leu Tyr Tyr Thr Pro Ile Arg Gly Leu Asn Phe His Ala625 630 635 640Ala Tyr Thr Phe Ile Asp Ala Asn Ile Thr Ser His Thr Met Val Thr

645 650 655Asn Pro Ala Asn Pro Lys Gly Pro Lys Lys Asp Ile Phe Gly Lys Lys

660 665 670Leu Pro Phe Val Ser Pro His Gln Phe Ile Leu Asp Ala Ser Tyr Thr

675 680 685Tyr Ala Lys Thr Thr Ile Gly Leu Ser Ser Phe Phe Tyr Ser Arg Ala

690 695 700Tyr Ser Asp Val Leu Asn Thr Val Pro Phe Thr Glu Tyr Ala Pro Thr705 710 715 720Ile Lys Asn Gly Ala Ile Val Thr Lys Thr Ala Gly Met Thr Pro Tyr

725 730 735Tyr Trp Val Trp Asn Leu Gln Ile Ser Thr Thr Leu Trp Glu Arg Lys

740 745 750Asn Gln Ser Val Asn Ala Ser Leu Gln Ile Asn Asn Ile Phe Asn Met

755 760 765Lys Tyr Trp Phe Ser Gly Ile Gly Thr Ser Pro Asn Gly Lys Glu Ala

770775780 Ala Pro Pro Arg Ser Ile Thr Ala Tyr Val Ser Tyr Asn Phe 785790795 (2) SEQ ID NO:904 information

Sequence properties:

(A) length: 798 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...798

(xi) sequence representation: 904 SEQ ID NO Met Arg Lys Val Ile Ile Met Asn Gly Tyr Leu Arg Val Lys Thr Pro 151015 Tyr Phe Lau Ala Ser Val Val Leu Tnr Phe Trp Thr Phe Asn Ser Phe

20 25 30Met Ser Ala Lys Asp Lys His His Phe Leu Lys Lys Val Thr Thr Thr

35 40 45Glu Gln Lys Phe Ser Ser Ser Ala Pro Ile Ser Trp Gln Ser Glu Glu

50 55 60Val Arg Asn Ser Thr Ser Ser Arg Thr Val Ile Ser Asn Lys Glu Leu65 70 75 80Lys Lys Thr Gly Asn Leu Asn Ile Glu Asn Ala Leu Gln Asn Val Pro

85 90 95Gly Ile Gln Ile Arg Asp Ala Thr Gly Thr Gly Val Leu Pro Lys Ile

100 105 110Ser Val Arg Gly Phe Gly Gly Gly Gly Asn Gly His Ser Asn Thr Asn

115 120 125Met Ile Leu Val Asn Gly Ile Pro Ile Tyr Gly Ala Pro Tyr Ser Asn

130 135 140Ile Glu Leu Ala Ile Phe Pro Val Thr Phe Gln Ser Val Asp Arg Ile145 150 155 160Asp Val Ile Lys Gly Gly Thr Ser Val Gln Tyr Gly Pro Asn Thr Phe

165 170 175Gly Gly Val Val Asn Val Ile Thr Lys Glu Ile Pro Lys Glu Trp Glu

180 185 190Asn Gln Ala Ala Glu Arg Ile Thr Phe Trp Gly Arg Ser Ser Asn Gly

195 200 205Asn Phe Val Asp Pro Lys Glu Lys Gly Lys Pro Leu Ala G1n Thr Leu

210 215 220Gly Asn Gln Met Leu Phe Asn Thr Tyr Gly Arg Thr Ala Gly Met Leu225 230 235 240Gly Lys Tyr Ile Gly Ile Ser Ala Gln Gly Asn Trp Ile Asn Gly Gln

245 250 255Gly Phe Arg Gln Asn Ser Pro Thr Lys Val Gln Asn Tyr Leu Leu Asp

260 265 270Ala Ile Tyr Lys Ile Asn Ala Thr Asn Thr Phe Lys Ala Tyr Tyr Gln

275 280 285Tyr Tyr Gln Tyr Asn Ser Tyr His Pro Gly Thr Leu Ser Ala Gln Asp

290 295 300Tyr Ala Tyr Asn Arg Phe Ile Asn Glu Arg Pro Asp Asn Gln Asp Gly305 310 315 320Gly Arg Ala Lys Arg Phe Gly Ile Val Tyr Gln Asn Tyr Phe Gly Asp

325 330 335Pro Asp Arg Lys Val Gly Gly Asp Phe Lys Phe Thr Tyr Phe Thr His

340 345 350Asp Met Ser Arg Asp Phe Gly Phe Ser Asn Gln Tyr Gln Ser Val Tyr

355 360 365Met Ser Gly Gln Asn Lys Ile Leu Pro Phe Lys Gly Lys Gly Glu Ile

370 375 380Ser Ala Lys Asn Pro Asn Cys Gly Leu Tyr Ser Tyr Ser Asp Thr Asn385 390 395 400Ser Pro Cys Trp Gln Phe Phe Asp Asn Ile Arg Arg Ser Val Val Asn

405 410 415Ala Phe Glu Pro Lys Leu Asn Leu Ile Val Asn Thr Gly Lys Val Lys

420 425 430Gln Thr Phe Asn Met Gly Met Arg Phe Leu Thr Glu Asp Leu Tyr Arg

435 440 445Arg Ser Thr Thr Arg Lys Asn Pro Ser Met Pro Asn Asn Gly Ser Gly

450 455 460Phe Asp Ala Gly Thr Ser Leu Asn Asn Phe Asn Asn Tyr Thr Ala Val465 470 475 480Tyr Ala Ser Asp Glu Ile Asn Phe Asn Asn Gly Met Leu Thr Ile Thr

485 490 495Pro Gly Leu Arg Tyr Thr Phe Leu Asn Tyr Glu Lys Lys Asp Ala Pro

500 505 510Pro Phe Lys Val Gly Gln Thr Pro Lys Thr Thr Lys Glu Arg Tyr Asn

515 520 525Gln Trp Asn Pro Ala Val Asn Val Gly Tyr Lys Pro Ile Lys Glu Leu

530 535 540Leu Phe Tyr Phe Asn Tyr Gln Arg Ser Tyr Ile Pro Pro Gln Phe Ser545 550 555 560Asn Ile Gly Asn Phe Val Gly Thr Ser Thr Asp Tyr Phe Gln Ile Phe

565 570 575Asn Val Met Glu Gly Gly Ser Arg Tyr Tyr Phe Asn His Gln Val Ser

580 585 590Phe Asn Ala Asn Tyr Phe Val Ile Phe Ala Asn His Tyr Phe Thr Gly

595 600 605Arg Tyr Gly Asp Asn Arg Glu Pro Val Asn Ala Arg Ser Gln Gly Val

610 615 620Glu Leu Glu Leu Tyr Tyr Thr Pro Ile Arg Gly Leu Asn Phe His Ala625 630 635 640Ala Tyr Thr Phe Ile Asp Ala Asn Ile Thr Ser His Thr Met Val Thr

645 650 655Asn Pro Ala Asn Pro Lys Gly Pro Lys Lys Asp Ile Phe Gly Lys Lys

660 665 670Leu Pro Phe Val Ser Pro His Gln Phe Ile Leu Asp Ala Ser Tyr Thr

675 680 685Tyr Ala Lys Thr Thr Ile Gly Leu Ser Ser Phe Phe Tyr Ser Arg Ala

690 695 700Tyr Ser Asp Val Leu Asn Thr Val Pro Phe Thr Glu Tyr Ala Pro Thr705 710 715 720Ile Lys Asn Gly Ala Ile Val Thr Lys Thr Ala Gly Met Thr Pro Tyr

725 730 735Tyr Trp Val Trp Asn Leu Gln Ile Ser Thr Thr Leu Trp Glu Arg Lys

740 745 750 Asn Gln Ser Val Asn Ala Ser Leu Gln Ile Asn Asn Ile Phe Asn Met

755 760 765Lys Tyr Trp Phe Ser Gly Ile Gly Thr Ser Pro Asn Gly Lys Glu Ala

770775780 Ala Pro Pro Arg Ser Ile Thr Ala Tyr Val Ser Tyr Asn Phe 785790795 (2) SEQ ID NO:905 information

Sequence properties:

(A) length: 277 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...277

(xi) sequence representation: 905 SEQ ID NO: Met Lys Thr Asn Gly Leu Phe Lys Met Trp Gly Leu Phe Leu Val Leu 151015 Ile Ala Leu Val Phe Asn Ala Cys Ser Asp Ser His Lys Glu Lys Lys

20 25 30Asp Ala Leu Glu Val Ile Lys Gln Arg G1y Val Leu Lys Val Gly Val

35 40 45Phe Ser Asp Lys Pro Pro Phe Gly Ser Val Asp Ser Lys Gly Asn Tyr

50 55 60Gln Gly Tyr Asp Val Val Ile Ala Lys Arg Met Ala Leu Asp Leu Leu65 70 75 80Gly Asp Glu Asn Lys Ile Glu Phe Ile Pro Val Glu Ala Ser Ala Arg

85 90 95Val Glu Phe Leu Lys Ala Asn Lys Val Asp Ile Ile Met Ala Asn Phe

100 105 110Thr Arg Thr Lys Glu Arg Glu Lys Val Val Asp Phe Ala Asn Pro Tyr

115 120 125Met Lys Val Ala Leu Gly Val Ile Ser Lys Asp Gly Val Ile Lys Asn

130 135 140Ile Glu Glu Leu Lys Asp Lys Glu Leu Ile Val Asn Lys Gly Thr Thr145 150 155 160Ala Asp Phe Tyr Phe Thr Lys Asn Tyr Pro Asn Ile Lys Leu Leu Lys

165 170 175Phe Glu Gln Asn Thr Glu Thr Phe Leu Ala Leu Leu Asn Asn Lys Ala

180 185 190Ile Ala Leu Ala His Asp Asn Thr Leu Leu Leu Ala Trp Val Lys Gln

195 200 205His Pro Glu Phe LysLeu Gly Ile Thr Ser Leu Gly Asp Lys Asp Val

210 215 220Ile Ala Pro Ala Ile Lys Lys Gly Asn Pro Lys Leu Leu Glu Trp Leu225 230 235 240Asn Asn Glu Ile Asp Ser Leu Ile Ser Ser Asp Phe Leu Lys Glu Ala

245 250 255Tyr Gln Glu Thr Leu Glu Pro Ile Tyr Gly Asp Gly Ile Lys Pro Glu

260 265 270Glu Ile Ile Phe Glu

275(2) SEQ ID NO:906 information

Sequence properties:

(A) length: 207 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...207

(xi) sequence representation: 906: Leu Asp Asn Phe Ile Ser Gln Tyr Ala Gln Arg Leu Ile Val Thr Asn 151015 Leu Ser Gln Ala Ile Arg Ile Tyr Gly Tyr Glu Val Gly Gly Thr Phe SEQ ID NO

20 25 30Arg Tyr Lys Gly Val Ser Leu Asn Val Gly Ile Ser Arg Thr Trp Pro

35 40 45Thr Thr Arg Gly Tyr Leu Met Ala Asp Ser Tyr Glu Leu Ala Ala Ser

50 55 60Thr Gly Asn Val Phe Ile Ile Lys Leu Asp Tyr Thr Ile Pro LysThr65 70 75 80Gly Ile Asn Leu Ala Trp Leu Ser Arg Phe Val Thr Gly Leu Asp Tyr

85 90 95Cys Gly Phe Asp Ile Tyr Leu Pro Asp Tyr Gly Thr Ala Glu Lys Pro

100 105 110Lys Thr Pro Thr Asp Leu Ala Lys Cys Gly Ser Gln Leu Gly Leu Val

115 120 125His Met His Lys Pro Gly Tyr Gly Val Ser Asn Phe Tyr Ile Asn Trp

130 135 140Ser Pro Lys Thr Lys Ser His Trp Lys Gly Leu Leu Leu Ser Ala Val145 150 155 160Phe Asn Asn Val Phe Asn Lys Phe Tyr Val Asp Gln Thr Ser Pro Tyr

165 170 175Val Met Ser Pro Asp Met Pro Gly Thr Asp Ala Ile Lys Arg Ala Ile

180 185 190Ala Glu Pro Gly Phe Asn Ala Arg Phe Glu Val Ala Tyr Lys Trp

195200205 (2) SEQ ID NO 907 information

Sequence properties:

(A) length: 244 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...244

(xi) sequence representation: 907: Met Lys Lys Ala Gly Phe Leu Phe Leu Ala Ala Met Ala Ile Ile Val 151015 Val Ser Leu Asn Ala Lys Asp Pro Asn Val Leu Arg Lys Ile Val Phe SEQ ID NO

20 25 30Glu Lys Cys Leu Pro Asn Tyr Glu Lys Asn Gln Asn Pro Ser Pro Cys

35 40 45Ile Glu Val Lys Pro Asp Ala Gly Tyr Val Val Leu Lys Asp Ile Asn

50 55 60Gly Pro Leu Gln Tyr Leu Leu Met Pro Thr Thr His Ile Ser Gly Ile65 70 75 80Glu Asn Pro Leu Leu Leu Asp Pro Ser Thr Pro Asn Phe Phe Tyr Leu

85 90 95Ser Trp Gln Ala Arg Asp Phe Met Ser Lys Lys Tyr Gly Lys Pro Ile

100 105 110Pro Asp Tyr Ala Ile Ser Leu Thr Ile Asn Ser Lys Lys Gly Arg Ser

115 120 125Gln Asn His Phe His Ile His Ile Ser Cys Ile Ser Leu Asp Val Arg

130 135 140Lys Gln Leu Asp Asn Asn Leu Lys Asn Ile Asn Ser Arg Trp Ser Pro145 150 155 160Leu Ser Gly Gly Leu Asn Gly His Lys Tyr Leu Ala Arg Arg Val Thr

165 l70 175Glu Ser Glu Leu Ala Gln Lys Ser Pro Phe Val Met Leu Ala Lys Glu

180 185 190Val Pro Asn Ala His Lys Arg Met Gly Asp Tyr Gly Leu Ala Val Val

195 200 205Gln Gln Ser Asp Asn Ser Phe Val Leu Leu Ala Thr Gln Phe Asn Pro

210215220 Leu Thr Leu Asn Arg Ala Ser Ala Glu Glu Ile Gln Asp His Glu Cys 225230235240 Ala Ile Leu Arg (2) SEQ ID NO 908information

Sequence properties:

(A) length: 228 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...228

(xi) sequence representation: SEQ ID NO 908: Met Val Phe Asp Arg Thr Thr Ser Val Arg Glu Lys Lys Ala Ala Lys 151015 Ala Leu Gly Ile Val Gly Ile Val Phe Phe Ile Leu Phe Gly Ile Val

20 25 30Ile Ser Gly Val Ala Ser Gln Lys Glu Trp Val Gln Gln Leu Asp Leu

35 40 45Phe Phe Ile Asp Leu Ile Arg Asn Pro Ala Pro Ile Gln Gly Ser Thr

50 55 60Trp Leu Ser Phe Val Phe Phe Ser Thr Trp Phe Ala Gln Ser Lys Leu65 70 75 80Thr Thr Pro Ile Ala Leu Leu Ile Gly Leu Trp Phe Gly Phe Gln Lys

85 90 95Arg Ile Ala Leu Gly Val Trp Phe Phe Phe Ser Ile Leu Leu Gly Glu

100 105 110Phe Thr Leu Lys Ser Leu Lys Leu Leu Val Ala Arg Pro Arg Pro Val

115 120 125Thr Asn Gly Glu Leu Val Phe Ala His Gly Phe Ser Phe Pro Ser Gly

130 135140His Ala Leu Ala Ser Ala Leu Phe Tyr Gly Ser Leu Ala Leu Leu Leu145 150 155 160Cys Tyr Ser Asn Ala Asn Asn Arg Ile Lys Thr Ile Gly Ala Ile Ile

165 170 175Leu Leu Phe Trp Ile Phe Leu Met Ala Tyr Asp Arg Val Tyr Leu Gly

180 185 190Val His Tyr Pro Ser Asp Val Leu Gly Gly Phe Leu Leu Gly Ile Ala

195 200 205Trp Ser Cys Cys Ser Leu Ala Leu Tyr Leu Gly Phe Leu Lys Arg Pro

210215220 Tyr Lys Ala Ala225(2) SEQ ID NO:909 information

Sequence properties:

(A) length: 157 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...157

(xi) sequence representation: SEQ ID NO:909: Met Lys Lys Phe Gly Leu Gly Val Tyr Leu Leu Leu Leu Gly Ile Leu 151015 Gly Gly Ser Leu Ile Ile Leu Gly Ala Ile Val Ala Pro Ile Val Phe

20 25 30Lys Ala Ser Ser Ile Leu Pro Glu Leu Asn Leu Thr Pro Phe Glu Ser

35 40 45Gly Lys Leu Met Ala Gln Ile Phe Val Arg Pha Asn Tyr Val Leu Gly

50 55 60Ala Ile Gly Phe Val Val Leu Leu Tyr Glu Ile Ile Ser Phe Ile Tyr65 70 75 80Tyr Lys Arg Ser Leu Val Tyr Leu Ile Leu Gly Val Ala Ile Gly Ala

85 90 95Leu Cys Leu Leu Phe Val Phe Tyr Tyr Thr Pro Tyr Ile Leu Asn Ala

100 105 ll0Gln Lys Val Gly Glu Val Ala Leu Gln Ser Ala Glu Phe Ala Arg Ser

115 120 125His Ala Gln Ser Glu Trp Leu Phe Lys Glu Leu Phe Val Leu Val Cys

110135140 Ala Leu Phe Phe Trp Arg Leu Phe Gly Lys Asn Ala Leu 145150155 (2) SEQ ID NO 910 information

Sequence properties:

(A) length: 110 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...110

(xi) sequence representation: 910: Leu Ile Asn Leu Leu Pro His His Tyr His Lys Phe Pro Pro Asn Ile 151015 Asn Pro Ser Leu Ile Ser Leu Lys Asp Arg Phe Leu Pro His Glu Lys SEQ ID NO

20 25 30His Ser Gln Lys Val Lys Lys Glu Cys Val Asn Leu Phe Glu Val Leu

35 40 45Ser Pro Leu His Lys Ile Asp Glu Lys TyrLeu Phe His Leu Lys Ile

50 55 60Ala Gly Glu Leu Ala Ser Met Gly Lys Ile Leu Ser Val Tyr Leu Ala65 70 75 80His Lys His Ser Ala Tyr Phe Ile Leu Asn Ala Leu Ser Tyr Gly Phe

85 90 95Ser His Gln Asp Arg Ala Ile Ile Cys Leu Leu Gly Ala Ile

100105110 (2) SEQ ID NO:911 information

Sequence properties:

(A) length: 215 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...215

(xi) sequence representation: 911 Met Lys Ser Phe Leu Lys Leu Phe Ala Gln Pro Leu Leu Val Val Leu 151015 Ala Phe Met Leu Leu Tyr Ala Leu Ala His Ala Val Leu Gly Phe Tyr SEQ ID NO

20 25 30Val Lys Lys Asp Ser Ala Pro Met Ser Pro Asn Val Glu Lys Ser Glu

35 40 45Thr Glu Arg Gln Asn Ser Thr Phe Ser Pro Lys Glu Glu Ala Asn Ala

50 55 60Thr Thr Thr Ala Thr Glu Gln Asn Pro Thr Lys Asp Thr Val Pro Pro65 70 75 80Leu Asp Thr Ala Thr Gln Lys Gln Glu Ile Lys Gln Glu Ile Lys Gln

85 90 95Glu Ile Lys Gln Glu Ile Lys Gln Glu Ile Lys Gln Glu Ile Lys Gln

100 105 110Glu Ile Lys Gln Glu Thr Lys Gln Glu Gln Glu Lys Glu Asn Lys Pro

115 120 125Lys Gln Asn Ser Val Ser Pro Val Gln Asn Asp Gln Lys Thr Pro Thr

130 135 140Thr Pro Leu Met Gly Lys Lys Pro Leu Glu Tyr Lys Val Ala Val Ser145 150 155 160Gly Val Asn Val Arg Ala Phe Pro Ser Thr Lys Gly Lys Ile Ile Gly

165 170 175Ser Leu Ile Lys Asn Lys Ser Val Lys Val Leu Glu Ile Gln Asn Asp

180 185 190Trp Ala Glu Ile Glu Phe Ser His Glu Thr Lys Gly Tyr Val Phe Leu

195 200 205Lys Leu Leu Lys Lys Ala Glu

210215 (2) SEQ ID NO 912 information

Sequence properties:

(A) length: 79 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...79

(xi) sequence representation: SEQ ID NO 912: Met Trp Pro Val Ala Leu Lys Gln Pro Asn Arg Val Ser His HisPhe 151015 Tyr Ile Met Ala Met Leu Phe Ile Leu Phe Asp Val Glu Ile Val Phe

20 25 30Met Phe Pro Trp Ala Ile Asp Phe Lys Lys Leu Gly Leu Phe Gly Leu

35 40 45Val Glu Met Leu Gly Phe Val Phe Phe Leu Ala Ile Gly Phe Ile Tyr

505560 Ala Leu Lys Arg Asn Ala Leu Ser Trp Gln Lys Leu Glu Val Lys 657075 (2) SEQ ID NO:913 information

Sequence properties:

(A) length: 416 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...416

(xi) sequence representation: 913: Met Cys Gly Met Phe Lys Asn Glu Ile Ser Ala Ile Gln Gly Met Ile 151015 Ala Asn Ala Gln Glu Ala Val Ala Gln Ala Lys Ile Val Ser Glu Asn SEQ ID NO

20 25 30Thr Gln Asn Gln Asn Ser Leu Asp Ala Gly LysPro Phe Asn Pro Tyr

35 40 45Thr Asp Ala Ser Phe Ala Glu Ser Met Leu Lys Asn Ala Gln Ala Gln

50 55 60Ala Glu Ile Leu Asn Gln Ala Glu Gln Val Val Lys Asn Phe Glu Lys65 70 75 80Ile Pro Thr Ala Phe Val Asn Asp Ser Leu Gly Val Cys Tyr Glu Val

85 90 95Gln Gly Gly Glu Arg Arg Gly Thr Asn Pro Gly Gln Thr Thr Ser Asn

100 105 110Thr Trp Gly Ala Gly Cys Ala Tyr Val Gly Gln Thr Ile Thr Asn Leu

115 120 125Lys Asn Ser Ile Ala His Phe Gly Thr Gln Glu Gln Gln Ile Gln Gln

130 135 140Ala Glu Asn Ile Ala Asp Thr Leu Val Asn Phe Lys Ser Arg Tyr Ser145 150 l55 160Glu Leu Gly Asn Thr Tyr Asn Ser Ile Thr Thr Ala Leu Ser Asn Ile

165 170 175Pro Asn Ala Gln Ser Leu Gln Asn Ala Val Ser Lys Lys Asn Asn Pro

180 185 190Tyr Ser Pro Gln Gly Ile Asp Thr Asn Tyr Tyr Leu Asn Gln Asn Ser

195 200 205Tyr Asn Gln Ile Gln Thr Ile Asn Gln Glu Leu Gly Arg Asn Pro Phe

210 215 220Arg Lys Val Gly Ile Val Ser Ser Gln Thr Asn Asn GIy Ala Met Asn225 230 235 240Gly Ile Gly Ile Gln Val Gly Tyr Lys Gln Phe Phe Gly Gln Lys Arg

245 250 255Lys Trp Gly Ala Arg Tyr Tyr Gly Phe Phe Asp Tyr Asn His Ala Phe

260 265 270Ile Lys Ser Ser Phe Phe Asn Ser Ala Ser Asp Val Trp Thr Tyr Gly

275 280 285Phe Gly Ala Asp Ala Leu Tyr Asn Phe Ile Asn Asp Lys Ala Thr Asn

290 295 300Phe Leu Gly Lys Asn Asn Lys Leu Ser Val Gly Leu Phe Gly GlyIle305 310 315 320Ala Leu Ala Gly Thr Ser Trp Leu Asn Ser Glu Tyr Val Asn Leu Ala

325 330 335Thr Met Asn Asn Val Tyr Asn Ala Lys Met Asn Val Ala Asn Phe Gln

340 345 350Phe Leu Phe Asn Met Gly Val Arg Met Asn Leu Ala Arg Pro Lys Lys

355 360 365Lys Asp Ser Asp His Ala Ala Gln His Gly Ile Glu Leu Gly Leu Lys

370 375 380Ile Pro Thr Ile Asn Thr Asn Tyr Tyr Ser Phe Met Gly Ala Glu Leu385 390 395 400Lys Tyr Arg Arg Leu Tyr Ser Val Tyr Leu Asn Tyr Val Phe Ala Tyr

405410415 (2) SEQ ID NO 914 information

Sequence properties:

(A) length: 114 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...114

(xi) sequence representation: 914: Met Ala Thr Ile Gln Pro Phe Asn His Ser Thr Ile Gln Pro Phe Asn 151015 His Ser Thr Ile Gln Pro Phe Asn His Ssr Ile Ile Gln Ser Phe Asn SEQ ID NO

20 25 30His Ser Thr Ile Gln Ala Thr Leu Pro Tyr Phe Tyr Asn Tyr Leu Ser

35 40 45Phe Tyr Lys Asn Leu Phe Lys Asn Pro Leu Phe Phe Ile Ile Pro Pro

50 55 60Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro65 70 75 80Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro

85 90 95Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro

100105110 Phe Ile (2) information SEQ ID NO:915

Sequence properties:

(A) length: 126 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...126

(xi) sequence representation: SEQ ID NO 915: Leu Val Ser Glu Tyr Trp Leu Lys Phe Phe Thr Arg Ser Phe Ser Lys 151015 Ser Thr Met Leu Phe Lys Thr Leu Leu Arg Ser Phe Phe Thr Phe Pro

20 25 30Val Glu Leu Ser Glu Asn Ile Thr Leu Gly Ser Thr Val Val Leu Ile

35 40 45Val Ala Glu Ala Val Ser Ala Leu Asn Lys Lys Val Val Ala Ala Lys

50 55 60Lys Asn Lys Ile Arg Phe Thr Pro Asn Ser Tyr Ile His Asn Arg Asn6570 75 80Lys Asn Arg Arg Tyr Ser Ser Leu Ser Pro Leu Leu Lys Ser Ser Ser

85 90 95Ile Tyr Lys Asn Pro Pro Arg Ile Gln Ala Ile Leu Ile Ile Leu Lys

100 105 110Tyr Arg Leu Ser Lys Gly Ile Tyr His Leu Gly Met Ile Leu

115120125 (2) SEQ ID NO:916 information

Sequence properties:

(A) length: 286 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...286

(xi) sequence representation: 916 SEQ ID NO: Met Lys Lys Ser Val Ile Val Gly Ala Ile Ser Leu Ala Met Thr Ser 151015 Leu Leu Ser Ala Glu Thr Pro Lys Gln Glu Lys Ala Ile Lys Thr Ser

20 25 30Pro Thr Lys Lys Gly Glu Arg Asn Ala Ala Phe Ile Gly Ile Asp Tyr

35 40 45Gln Leu Gly Met Leu Ser Thr Thr Ala Gln Asn Cys Ser His Gly Asn

50 55 60Cys Asn Gly Asn Gln Ser Gly Ala Tyr Gly Ser Asn Thr Pro Asn Met65 70 75 80Pro Thr Ala Ser Asn Pro Thr Gly Gly Leu Thr His Gly Ala Leu Gly

85 90 95Thr Arg Gly Tyr Lys Gly Leu Ser Asn Gln Gln Tyr Ala Ile Asn Gly

100 105 110Phe Gly Phe Val Val Gly Tyr Lys His Phe Phe Lys Lys Ala Pro Gln

115 120 125Phe Gly Met Arg Tyr Tyr Gly Phe Phe Asp Phe Ala Ser Ser Tyr Tyr

130 135 140Lys Tyr Tyr Thr Tyr Asn Asp Tyr Gly Met Arg Asp Ala Arg Lys Gly145 150 155 160Ser Gln Ser Phe Met Phe Gly Tyr Gly Ala Gly Thr Asp Val Leu Phe

165 170 175Asn Pro Ala Ile Phe Asn Arg Glu Asn Leu His Leu Gly Phe Phe Leu

180 185 190Gly Val Ala Ile Gly Gly Thr Ser Trp Gly Pro Thr Asn Tyr Tyr Phe

195 200 205Lys Asp Leu Ala Glu Glu Tyr Arg Gly Ser Phe His Pro Ser Asn Phe

210 215 220Gln Val Leu Val Asn Gly Gly Ile Arg Leu Gly Thr Lys His Gln Gly225 230 235 240Phe Glu Ile Gly Leu Lys Ile Gln Thr Ile Arg Asn Asn Tyr Tyr Thr

245 250 255Ala Ser Ala Asp Asn Val Pro Glu Gly Thr Thr Tyr Arg Phe Thr Phe

260 265 270His Arg Pro Tyr Ala Phe Tyr Trp Arg Tyr Ile Val Ser Phe

275280285 (2) SEQ ID NO 917 information

Sequence properties:

(A) length: 285 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...285

(xi) sequence representation: SEQ ID NO 917 Val Lys Arg Ile Leu Phe Phe Leu Ala Ala Thr Thr Phe Leu Leu Arg 15l 015 Ala Glu Thr Ala Ser Ala Thr Ile Asn Thr Thr Val Asp Pro Asn Val

20 25 30Met Phe Ser Glu Ser Ser Thr Gly Asn Val Lys Lys Asp Arg Lys Arg

35 40 45Val Leu Lys Sar Met Val Asp Leu Glu Lys Glu Arg Val Lys Asn Phe

50 55 60Asn Gln Tyr Ser Glu Thr Lys Met Ser Lys Gly Asp Leu Ser Ala Phe65 70 75 80Gly Ala Phe Phe Lys Gly Ser Leu Glu Asp Cys Val Glu Gln Lys Ile

85 90 95Cys Tyr Tyr Glu His Arg Asn Gly Lys Val Ser Phe Val Val Asn Asp

100 105 110Arg Glu Lys Phe Tyr Lys His Val Leu Lys Asp Leu Gly Thr Glu Leu

115 120 125Ser Leu Pro Leu Phe Asn Trp Leu Tyr Lys Gly Ser Asp Phe Gly Ala

130 135 140Leu His Glu Gln Phe Gly Asp Met Tyr Asp Gly Tyr Ile Lys Tyr Leu145 150 155 160Ile Ser Met Val Arg Val Ser Gln Lys Glu Lys Ala Arg Lys Val Asp

165 170175Ala Ile Val Leu Lys Lys Met Glu Glu Gln Ala Glu Lys Asp Thr Lys

180 185 190Ala Ala Phe Gln Lys Arg Ser Ser Gly Glu Leu Glu Ser His Thr Asp

195 200 205Ser Pro Glu Phe Ile Ser Ser Ser Lys Thr Gln Asn Ser Ser Asn Pro

210 215 220Asp Leu Asp Pro Met Thr Asn Ala Asn Thr Leu Lys Glu Thr Ala Ser225 230 235 240Lys Glu Pro Glu Thr Ser Ser Lys Lys Glu Lys Lys Pro Lys Lys Lys

245 250 255Arg Arg Leu Ser Lys Lys Glu Lys Gln Gln Gln Ala Leu Gln Gln Glu

260 265 270Phe Glu Lys Gln Ile Ser Asp Ser Ser Lys Ser Glu Lys

275280285 (2) SEQ ID NO 918 information

Sequence properties:

(A) length: 75 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...75

(xi) sequence representation: 918 SEQ ID NO: Met Pro Lys Glu Asn Thr Thr His Glu Asp Ala Leu Ala Lys Cys Phe 151015 Ala Pro Ala Ile Phe Lys Ala lle Met Leu Asn Lys Leu Ile Leu Ala

20 25 30Val Val Ala Ala Pro Ile Ile Lys Met Leu Lys Leu Ser Lys Glu Ile

35 40 45Trp Trp Lys Lys Met Gly Lys Lys His Ala Ile Asp Phe Lys Met Arg

505560 Ile Lys Ile Leu Ala Ser Leu Ala Pro Ser Phe 657075 (2) SEQ ID NO:919 information

Sequence properties:

(A) length: 134 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...134

(xi) sequence representation: 919: Met Cys Gln Ile Gln Cys Leu Leu Ile Leu Leu Ser Ile Asn Ile Val 151015: 151015 Ser Ala Ile Ile Val Tyr Phe Phe Gln Ala Phe Gln Gly Val Leu Asn SEQ ID NO

20 25 30Phe Glu Gly Gly Phe Leu Gly Phe Phe Ile Val Ala Leu Ser Ser Tyr

35 40 45Tyr Gly Val Lys Lys Arg Leu Asp Leu Arg Lys Gln Asp Ser Lys Glu

50 55 60Lys Glu Glu Lys Gln Lys Phe Gln Lys Pne Ala Leu Gly Leu Glu Met65 70 75 80Ser Phe Asn Val Trp Arg Leu Gly Gly Tyr Gly Val Leu Leu Gly Ile

85 90 95Leu Gly Val Leu Leu Phe Leu His Leu Phe Asn Gly Leu Pro Phe Leu

l00105 110Ile Gly Val Phe Val Ser Ser Leu Ser Ser Ala Leu Leu Arg Phe Leu

115 120 125Asn Asn Asn Gly Lys Phe

130(2) SEQ ID NO 920 information

Sequence properties:

(A) length: 92 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...92

(xi) sequence representation: 920: Met Ala Cys Glu Phe Leu Lys Lys Pro Lys Tyr Tyr Lys Phe Ile Glu 151015 Gly Ala Asn Tyr Leu Ser Leu Gly Leu Ser Met Val Val Ala Ile Leu SEQ ID NO

20 25 30Met Gly Val Ala Ile Gly Tyr Gly Leu Lys Lys Leu Thr His Ile Ser

35 40 45Trp Leu Phe Trp Leu Gly Val Ile Trp Gly Val Leu Ala Ser Phe Leu

50 55 60Asn Val Tyr Lys Ala Tyr Lys Asn Met Gln Lys Asp Tyr Glu Glu Leu65 70 75 80Ala Lys Asp Pro Lys Tyr Thr Gln Asn Lys Thr Lys

8590 (2) SEQ ID NO:921 information

Sequence properties:

(A) length: 80 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...80

(xi) sequence representation: SEQ ID NO:921: Met Glu Asp Phe Leu Tyr Asn Thr Leu Tyr Phe Ile Glu Asp Tyr Lys 151015 Leu Val Val Ile Phe Ser Phe Ile Gly Leu Ile Ala Leu Phe Phe Leu

20 25 30Tyr Lys Phe Ile Lys Thr Gln Lys Lys Val Phe Lys Asp Lys Ala Asn

35 40 45Gln Pro Gln Lys Lys Lys Ser Phe Lys Glu Ile Ile Ile Asp Gly Leu

505560 Lys Glu Arg Val Lys Thr Phe Gly Phe Arg Leu Gln Ala Ile Leu Leu 65707580 (2) SEQ ID NO:922 information

Sequence properties:

(A) length: 363 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...363

(xi) sequence representation: 922: Met Ala Ile Asp Leu Ala Glu Val Thr Gly Ala Lys Ala Ala Gln Glu 151015Arg Lys Lys Glu Gln Pro Thr Ile Ala Asn Gly Leu Asp Lys Asn Ala SEQ ID NO

20 25 30Phe Met Lys Leu Phe Leu Glu Gln Leu Lys Asn Gln Asp Pro Thr Ala

35 40 45Pro Met Glu Thr Asp Lys Ile Ile Thr Gln Thr Ala Gln Leu Thr Gln

50 55 60Val Glu Met Gln Glu Glu Asn Lys Lys Thr Met Gln Glu Val Ala Ser65 70 75 80Ala Met Lys Ser Asn Lys Glu Thr Asn Glu Ser Leu Lys Asp Phe Gln

85 90 95Gly Ala Leu Lys Asp Thr Met Glu Asn Leu Asn Lys Gly Met Asp Asp

100 105 110Ser Leu Lys Ala Asn Asn Ala Leu Arg Glu Val Ser Ala Leu Asn Ser

115 120 125Val Ser Met Ile Gly Lys Ile Ala Glu Thr Asp Val Ser Gly Ala Asn

130 135 140Phe Asp Gly Asn Asn Lys Leu Ser Phe Ser Leu Phe Phe Asp Glu Lys145 150 155 160Ile Asp Ala Ser Lys Gly Val Pro Ala Ile Gln Ile Leu Asn Glu Asn

165 170 175Asn Glu Leu Val Lys Thr Ile Pro Leu Lys Asp Tyr Asn Gly Gln Lys

180 185 190Gly Tyr Ile Asn Phe Glu Trp Asp Gly Thr Asn Glu Lys Gly Glu Lys

195 200 205Val Pro Lys Gly Asn Tyr Lys Ile Lys Ala Glu Tyr Asn Leu Asp Ser

210 215 220Gln Ser Lys Gln Tyr Leu Gln Thr Arg Ile Gly Arg Gly Glu Val Glu225 230 235240Ser Val Ile Phe Asp Lys Gly Lys Pro Met Leu Arg Met Gly Glu Met

245 250 255Ile Leu Pro Ile Asp Ser Ala Ile Glu Phe Tyr Lys Pro Asp Gln Lys

260 265 270Pro Leu Asp Gln Lys Leu Ser Asp Gln Lys Pro Gln Lys Leu Ser Glu

275 280 285Gln Lys Ala Leu Glu Gln Lys Ile Ser Glu Gln Lys Pro Gln Glu Pro

290 295 300Leu Asp Gln Lys Leu Ser Asp Gln Lys Pro Gln Lys Pro Leu Glu Gln305 310 315 320Lys Ile Ser Glu Gln Lys Pro Leu Asp Gln Lys Leu Ser Asp Gln Lys

325 330 335Pro Gln Lys Pro Leu Glu Gln Lys Ile Ser Glu Gln Lys Pro Leu Asp

340 345 350Gln Lys Pro Gln Thr Pro Pro Lys Glu Thr Ala

355360 (2) SEQ ID NO 923 message

Sequence properties:

(A) length: 217 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...217

(xi) sequence representation: SEQ ID NO 923: Leu Lys His Leu Ala Pro Leu Ile His Ile Pro Phe Lys Ala Leu Trp 151015 Leu Gly Thr Ala Leu Ser Met Phe LeuSer Leu Asn Leu Asn Ala Glu

20 25 30Glu Asn Pro Thr Lys Thr Glu Pro Lys Pro Ala Lys Gly Val Lys Asn

35 40 45Lys Pro Lys Ser Pro Val Thr Asn Val Met Met Thr Asn Cys Asp Asn

50 55 60Leu Lys Asp Phe Asn Ala Lys Gln Lys Glu Val Leu Lys Ala Ala Tyr65 70 75 80Gln Phe Gly Ser Lys Glu Asn Leu Gly Tyr Glu Met Ala Gly Ile Ala

85 90 95Trp Lys Glu Ser Cys Ala Gly Thr Tyr Lys Ile Asn Phe Ser Asn Pro

100 105 110Ser Ala Gly Ile Tyr His Ala Tyr Ile Pro Ser Val Leu Lys Ser Tyr

115 120 125Gly His Asn Asn Ser Pro Phe Leu Arg Asn Val Met Gly Glu Leu Leu

130 135 140Ile Lys Asp Asp Ala Phe Ala Ser Glu Val Ala Leu Lys Glu Leu Leu145 150 155 160Tyr Trp Lys Thr Arg Tyr His Asp Asn Leu Lys Asp Met Ile Lys Ser

165 170 175Tyr Asn Lys Gly Ser Arg Trp Glu Lys Asn Glu Lys Ala Asn Ala Asp

180 185 190Ala Glu Lys Tyr Tyr Glu Glu Ile Gln Asp Arg Ile Arg Arg Leu Lys

195 200 205Glu Ser Lys Ile Phe Glu Leu Ala Val

210215 (2) SEQ ID NO 924 information

Sequence properties:

(A) length: 366 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...366

(xi) sequence representation: 924: Met Gln Phe Gln Lys Thr Leu Leu Ser Leu Ser Leu Leu Phe Leu Ser 151015 Tyr Cys Ile Ala Glu Glu Asn G1y Ala Tyr Ala Ser Val Gly Phe Glu

20 25 30Tyr Ser Ile Ser His Ala Val Glu His Asn Asn Pro Phe Leu Asn Gln

35 40 45Glu Arg Ile Gln Thr Ile Ser Asn Ala Gln Asn Lys Ile Tyr Lys Leu

50 55 60Asn Gln Val Lys Asn Glu Ile Thr Asn Met Pro Asn Thr Phe Asn Tyr65 70 75 80Ile Asn Asn Ala Leu Lys Asn Asn Ala Lys Leu Thr Pro Thr Glu Lys

85 90 95Gln Ala Glu Thr Tyr Tyr Leu Gln Ser Thr Leu Gln Asn Ile Glu Lys

100 105 110Ile Val Met Leu Ser Gly Gly Val Ala Ser Asn Pro Lys Leu Ala Gln

115 120 125Ala Leu Glu Lys Met Gln Glu Pro Ile Thr Asn Pro Leu Glu Leu Val

130 135 140Glu Asn Leu Lys Asn Leu Glu Leu Gln Phe Ser Gln Ser Gln Asn Ser 145 150 155 160Met Leu Ser Ser Leu Ser Ser Gln Ile Ala Gln Ile Ser Asn Ser Leu

165 170 175Asn Ala Leu Asp Pro Ser Ser Tyr Ser Lys Asn Val Ser Ser Met Tyr

180 185 190Gly Val Gly Leu Ser Val Gly Tyr Lys His Phe Phe Thr Lys Lys Lys

195 200 205Asn Gln Gly Phe Arg Tyr Tyr Leu Phe Tyr Asp Tyr Gly Tyr Thr Asn

210 215 220Phe Gly Phe Val Gly Asn Gly Phe Asp Gly Leu Gly Lys Met Asn Asn225 230 235 240His Leu Tyr Gly Leu Gly Ile Asp Tyr Leu Phe Asn Phe Ile Asp Asn

245 250 255Ala Gln Lys His Ser Ser Val Gly Phe Tyr Val Gly Phe Ala Leu Ala

260 265 270Gly Ser Ser Trp Val Gly Ser Gly Leu Gly Met Trp Val Ser Gln Met

275 280 285Asp Phe Ile Asn Asn Tyr Leu Thr Asp Tyr Arg Ala Lys Met His Thr

290 295 300Ser Phe Phe Gln Ile Pro Leu Asn Phe Gly Val Arg Val Asn Val Asp305 310 315 320Arg His Asn Gly Phe Glu Met Gly Leu Lys Ile Pro Leu Ala Val Ash

325 330 335Ser Phe Tyr Glu Thr His Gly Lys Gly Leu Asn Ala Ser Leu Phe Phe

340 345 350Lys Arg Leu Val Met Phe Asn Val Ser Tyr Val Tyr Ser Phe

355360365 (2) SEQ ID NO:925 information

Sequence properties:

(A) length: 366 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...366

(xi) sequence representation: 925: Met Gln Phe Gln Lys Thr Leu Leu Ser Leu Ser Leu Leu Phe Leu Ser 151015 Tyr Cys Ile Ala Glu Glu Asn Gly Ala Tyr Ala Ser Val Gly Phe Glu SEQ ID NO

20 25 30Tyr Ser Ile Ser His Ala Val Glu His Asn Asn Pro Phe Leu Asn Gln

35 40 45Glu Arg Ile Gln Thr Ile Ser Asn Ala Gln Asn Lys Ile Tyr Lys Leu

50 55 60Asn Gln Val Lys Asn Glu Ile Thr Asn Met Pro Asn Thr Phe Asn Tyr65 70 75 80Ile Asn Asn Ala Leu Lys Asn Asn Ala Lys Leu Thr Pro Thr Glu Lys

85 90 95Gln Ala Glu Thr Tyr Tyr Leu Gln Ser Thr Leu Gln Asn Ile Glu Lys

100 105 110Ile Val Met Leu Ser Gly Gly Val Ala Ser Asn Pro Lys Leu Ala Gln

115 120 125Ala Leu Glu Lys Met Gln Glu Pro Ile Thr Asn Pro Leu Glu Leu Val

130 135 140Glu Asn Leu Lys Asn Leu Glu Leu Gln Phe Ser Gln Ser Gln Asn Ser145 150 155 160Met Leu Ser Ser Leu Ser Ser Gln Ile Ala Gln Ile Ser Asn Ser Leu

155 170 175Asn Ala Leu Asp Pro Ser Ser Tyr Ser Lys Asn Val Ser Ser Met Tyr

180 185 190Gly Val Gly Leu Ser Val Gly Tyr Lys His Phe Phe Thr Lys Lys Lys

195 200 205Asn Gln Gly Phe Arg Tyr Tyr Leu Phe Tyr Asp Tyr Gly Tyr Thr Asn

210 215 220Phe Gly Phe Val Gly Asn Gly Phe Asp Gly Leu Gly Lys Met Asn Asn225 230 235 240His Leu Tyr Gly Leu Gly Ile Asp Tyr Leu Phe Asn Phe Ile Asp Asn

245 250 255Ala Gln Lys His Ser Ser Val Gly Phe Tyr Val Gly Phe Ala Leu Ala

260 265 270Gly Ser Ser Trp Val Gly Ser Gly Leu Gly Met Trp Val Ser Gln Met

275 280 285Asp Phe Ile Asn Asn Tyr Leu Thr Asp Tyr Arg Ala Lys Met His Thr

290 295 300Ser Phe Phe Gln Ile Pro Leu Asn Phe Gly Val Arg Val Asn Val Asp305 310 315 320Arg His Asn Gly Phe Glu Met Gly Leu Lys Ile Pro Leu Ala Val Asn

325 330 335Ser Phe Tyr Glu Thr His Gly Lys Gly Leu Asn Ala Ser Leu Phe Phe

340 345 350Lys Arg Leu Val Met Phe Asn Val Ser Tyr Val Tyr Ser Phe

355360365 (2) SEQ ID NO:926 information

Sequence properties:

(A) length: 174 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...174

(xi) sequence representation: SEQ ID NO:926: Leu Asn Thr Met Asn Ser Val Leu Glu Cys Lys Glu Leu Ala Leu Tyr 151015 Gly Gly Ser Phe Asp Pro Leu His Lys Ala His Leu Ala Ile Ile Glu

20 25 30Gln Thr Leu Glu Leu Leu Pro Phe Val Gln Leu Ile Val Leu Pro Ala

35 40 45Tyr Gln Asn Pro Phe Lys Lys Pro Cys Phe Leu Asp Ala Lys Thr Arg

50 55 60Phe Lys Glu Leu Glu Arg Ala Leu Lys Gly Met Pro Arg Val Leu Leu65 70 75 80Ser Asp Phe Glu Ile Lys Gln Glu Arg Ala Val Pro Thr Ile Glu Ser

85 90 95Val Leu His Phe Gln Lys Leu Tyr Arg Pro Lys Thr Leu Tyr Leu Val

100 105 110Ile Gly Ala Asp Cys Leu Arg His Leu Ser Ser Trp Thr Asn Ala Lys

115 120 125Glu Leu Leu Lys Arg Val Glu Leu Val Val Phe Glu Arg Ile Gly Tyr

130 135 140Glu Glu Ile Gln Phe Lys Gly Arg Tyr His Pro Leu Lys Gly Ile Asp145 150 155 160Ala Pro Ile Ser Ser Ser Ala Ile Arg Ala Ser Leu Gly Val

165170 (2) SEQ ID NO 927information

Sequence properties:

(A) length: 376 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...376

(xi) sequence representation: SEQ ID NO 927 Met Arg Phe Phe Cys Phe Phe Leu Phe Phe Leu Thr Phe Ser Asn Alal 51015 Gln Ile Met Met Thr Phe Asp Ser Gln Thr Asn Ala Lys Leu Ser Arg

20 25 30Ser Asn Glu Gln Leu Ser Asp Met Leu Tyr Lys Leu Asn Glu Ser Leu

35 40 45Arg Ile Tyr Gln Asn Val Leu Ser Asn Asn Gln Asp Gln Leu Lys Glu

50 55 60Ile Lys Lys Ala Asn Ser Thr Leu Thr Ser Gln Arg Arg Phe Phe Asn65 70 75 80Ala Ser Gln Ile Arg Leu Met Asp Thr Asp Ala Leu Leu Lys Gln Ser

85 90 95Ala Leu Glu Leu Glu Lys Leu Gln Ala Leu Glu Lys His Leu Lys Glu

100 105 110Ser Met Glu His Glu Arg Leu Ile Lys Glu Ser Gln Ala Leu Phe Leu

115 120 125Gln Glu His Cys Pro Tyr Leu Ser Gly Val Lys Asn Leu Glu Glu Ala

130 135 140Ser Asn Ala Leu Glu Val Gln Glu Lys Asn Asn Ala Leu Phe Leu Leu145 150 155 160Lys Glu Pro Lys Leu Phe His Leu Leu Ser Arg Leu Asp Leu Met Ser

165 170 175Ala Leu Asn Ala Leu Cys Asp Gln Val Leu Glu Asn Glu Ile Gln Asp

180 185 190Gln Gln Ser His Asn Lys Thr Leu Glu Tyr Asn Ala Leu Met Asn His

195 200 205Asp Phe Gln Ala Tyr Lys Ala Met Arg Leu Lys Lys Ile Lys Asn Lys

210 215 220Leu Gln Ser Gln Ile Gln Ala Lys Glu Asp Ala Leu Lys Thr Phe Leu225 230 235 240Pro Leu Glu Lys Arg Leu Glu Thr Leu Lys Ser Arg Phe Leu Cys Asp

245 250 255Lys Glu Asn Leu Lys Ser Cys Ala Asn Gln Leu Gln Gln Arg Tyr Gln

260 265 270Asn Ala Leu Ile Glu Arg Asp Lys Glu Leu Lys Asn Ala Lys Asn Asn

275 280 285Lys Glu Lys His Ala Leu Ile Leu Ala Asn Tyr Glu His Thr Leu Lys

290 295 300Thr Leu Asn Ile Glu Phe Leu Ser Glu Leu Ser Glu Gln Met Ala Phe305 310 315 320Leu Asn Glu Thr Met Ala Leu Asn Ala Gln Val Leu Ala Leu Leu Ala

325 330 335Gln Gln Gln Thr Lys Lys Pro Phe Asn Val Ser Asp Gly Leu Ser Gly

340 345 350Gly Lys Ala Leu Ile Lys Asn Ile Arg Leu Asp Pro His Gly Phe Pro

355 360365Ser Phe Lys Asn Phe Lys Gln Glu

370375 (2) SEQ ID NO 928 information

Sequence properties:

(A) length: 229 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...229

(xi) sequence representation: SEQ ID NO:928: Val Lys Gly Glu Lys Asn Ala Trp Tyr Leu Gly Ile Ser Tyr Gln Val 151015 Gly Gln Ala Ser Gln Ser Val Lys Asn Pro Pro Lys Ser Ser Glu Phe

20 25 30Asn Tyr Pro Lys Phe Pro Val Gly Lys Thr Asp Tyr Leu Ala Val Met

35 40 45Gln Gly Leu Gly Leu Thr Val Gly Tyr Lys Gln Phe Phe Gly Glu Lys

50 55 60Arg Trp Phe Gly Ala Arg Tyr Tyr Gly Phe Met Asp Tyr Gly His Ala65 70 75 80Val Phe Gly Ala Asn Ala Leu Thr Ser Asp Asn Gly Gly Val Cys Lys

85 90 95Leu Asn Glu Pro Cys Ala Thr Lys Val Gly Thr Met Gly Asn Leu Ser

100 105 110Asp Met Phe Thr Tyr Gly Val Gly Ile Asp Thr Leu Tyr Asn Val Ile

115 120 125Asn Lys Glu Asp Ala Ser Phe Gly Phe Phe Phe Gly Ala Gln Ile Ala

130 135 140Gly Asn Ser Trp Gly Asn Thr Thr Gly Ala Phe Leu Glu Thr Lys Ser145 150 155 160Pro Tyr Lys His Thr Ser Tyr Ser Leu Asp Pro Ala Ile Phe Gln Phe

165 170 175Leu Phe Asn Leu Gly Ile Arg Thr His Ile Gly Gln His Gln Glu Phe

l80 185 190Asp Phe Gly Val Lys Ile Pro Thr Ile Asn Val Tyr Tyr Phe Asn His

195 200 205Gly Asn Leu Ser Phe Thr Tyr Arg Arg Gln Tyr Ser Leu Tyr Val Gly

210215220 Tyr Arg Tyr Asn Phe225(2) SEQ ID NO:929 message

Sequence properties:

(A) length: 479 an amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...479

(xi) sequence representation: SEQ ID NO 929: Leu Lys Asn His Ser Phe Lys Lys Thr Ile Ala Leu Ser Leu Leu Ala 151015 Ser Met Ser Leu Cys Asn Ala Glu Glu Asp Gly Ala Phe Phe Val Ile

20 25 30Asp Tyr Gln Thr Ser Leu Ala Arg Gln Glu Leu Lys Asn Pro Gly Phe

35 40 45Thr GlnAla Gln Glu Leu Lys Gln Leu Ile Arg Asp Gly Ala Val Arg

50 55 60Leu Gln Thr Ser Ala Ile Pro Leu Ser Tyr Tyr Leu Asp Ile Leu Gly65 70 75 80Asn Lys Thr Lys Thr Leu Leu Ser Glu Ser Leu Lys Asn Asn Pro Gln

85 90 95Gln Pro Asn Gly Gln Pro Asn Gln Ala Leu Val Asn Leu Glu Gln Ser

100 105 110Leu Gly Ile Leu Gly Lys Leu Leu Asp Leu Ser Gln Gln Tyr Ala Ser

115 120 125Glu Gly Val Ile Lys Pro Leu Val Val Asp Val Gly Lys Glu Gln Ile

130 135 140Gly Ile Thr Asp Ser Met Leu Leu Val Ala Gln Asn Ile Val Leu Ala145 150 155 160Leu Gly Gln Val Asp Leu Ser Lys lle Gln Gln Asn Asn Gly Asn Gln

165 170 175Gln Leu Tyr Glu Asn Ile Met Lys Val Met Leu Leu Gly Thr Gly Gly

180 185 190Thr Asn Gly Ala Tyr Asn Gly Val Ser Val Gly Asp Ile Ala Thr Gly

195 200 205Met Gln Asn Phe Pro Ser Gln Thr Gly Leu Ile Gly Ala Asn Ser Thr

210 215 220Val Ser Glu Leu Asn Ala Leu Ile Lys Ser Gly Ile Ser Leu Asp Arg225 230 235 240Glu Thr Leu Gly Leu Gly Ser Phe Ile Glu Lys Asn Ile Cys Ser Gly

245 250 255Ala Ser Ser Cys Phe Ser Gly Asn Gln Leu Ile Tyr Lys Lys Gly Leu

260 265 270Asp Arg Thr Ile Asn Ile IleAsn Ala Val Leu Gly Gln Phe Glu Ser

275 280 285Ser Ala Ser Ser Leu Tyr Lys Ile Ser Tyr Ile Pro Asn Leu Phe Ser

290 295 300Leu Lys Asp Tyr Gln Ser Ala Ser Met Asn Gly Phe Gly Ala Lys Met305 310 315 320Gly Tyr Lys Gln Phe Phe Thr His Lys Lys Asn Ile Gly Leu Arg Tyr

325 330 335Tyr Gly Phe Leu Asp Tyr Gly Tyr Ala Asn Phe Gly Asp Thr Asn Leu

340 345 350Lys Val Gly Ala Asn Leu Val Thr Tyr G1y Val Gly Thr Asp Phe Leu

355 360 365Tyr Asn Val Tyr Glu Arg Ser Arg Arg Arg Glu Arg Thr Thr Ile Gly

370 375 380Leu Phe Phe Gly Ala Gln Ile Ala Gly Gln Thr Trp Ser Thr Asn Val385 390 395 400Thr Asn Leu Leu Ser Gly Gln Arg Pro Asp Val Lys Ser Ser Ser Phe

405 410 415Gln Phe Leu Phe Asp Leu Gly Val Arg Thr Asn Phe Ala Lys Thr Asn

420 425 430Phe Asn Lys His Arg Leu ASp Gln Gly Ile Glu Phe Gly Val Lys Ile

435 440 445Pro Val Ile Ala His Lys Tyr Phe Ala Thr Gln Gly Ser Ser Ala Ser

450455460 Tyr Met Arg Asn Phe Ser Phe Tyr Val Gly Tyr Ser Val Gly Phe 465470475 (2) SEQ ID NO:930 information

Sequence properties:

(A) length: 179 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...179

(xi) sequence representation: 930: Met Ala Ser Leu Ala Phe Val Gln Ala Phe Leu Glu Ser Phe Lys Gly 15l 015 Phe Leu Ser Gln Ala Thr Leu Ile Ser Val Leu Ile Ala Ser Val Leu SEQ ID NO

20 25 30Ile Leu Phe Cys Ala Ile Leu Leu Leu Leu Ala Leu Leu Leu Arg Asn

35 40 45Arg Trp Ala Ser Tyr Ile Thr Thr Ala Ala Phe Leu Gly Ala Phe Leu

50 55 60Ser Met Pro Phe Val Leu Asn Val Leu Leu Thr Gln Ala Ile Tyr Pro65 70 75 80Ile Glu Thr Arg Ile Leu His Ala Asn Pro Leu Ser Tyr Ser Asn Ala

85 90 95Phe Ser Leu Gln Val Gly Val Lys Asn Ile Ser Lys Phe Ser Leu Asn

100 105 110Lys Cys Val Leu Arg Leu Glu Val Leu Lys Asn Pro His Asn Phe Val

115 120 125Glu Glu Arg Ala Phe Lys Trp Phe Val Lys Lys Ser Tyr Glu Lys Thr

130 135 140Phe Lys Glu Lys Ile Leu Pro Glu Glu Ser Lys Val Phe Ser Phe Phe145 150 155 160Ile Asp Asp Tyr Pro Tyr Ser Lys Thr Ala Pro Tyr Gln Val Ser Leu

165170175 Phe Cys Leu (2) SEQ ID NO:931 information

Sequence properties:

(A) length: 129 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...129

(xi) sequence representation: SEQ ID NO. 931: Leu Gly Glu Leu Leu Gln Ala Ser Ala Pro Tyr Ala Ile Ala Pro Val 151015 Glu Leu Ile Val Val Phe Tyr Lys Asn Glu Tyr Lys Arg Lys Lys Gln

20 25 30Thr Ser Thr Met Ser Arg Glu Glu Phe Leu Leu Tyr Thr Asn Gly Leu

35 40 45Trp Asn Phe Ser Gly Glu Ser Lys Lys Arg Leu Lys His Pro Ala Pro

50 55 60Phe Pro Arg Glu Leu Pro Arg Arg Cys Ile Gln Leu Phe Ser Phe Leu65 70 75 80Glu Asp Thr Ile Phe Asp Pro Phe Ser Gly Ser Gly Thr Thr Ile Leu

85 90 95Glu Ala Asn Ala Leu Gly Arg Phe Ser Val Gly Leu Glu Ile Glu Lys

100 105 110Glu Tyr Cys Glu Leu Ser Lys Lys Arg Ile Leu Glu Ser Leu Ser Leu

115120125 Val (2) SEQ ID NO 932 information

Sequence properties:

(A) length: 327 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...327

(xi) sequence representation: 932: Val Leu Lys Gly Leu Lys Lys Ala Phe Lys Glu Arg Phe Cys Ser Gln 151015 Val Tyr Ile Ser Phe Asn Val Asp His Asn Leu Leu Ser Ala Gln Val SEQ ID NO

20 25 30Leu Arg Val Lys Asn His Arg Ile Lys Glu Lys Phe Phe Lys Thr Phe

35 40 45Glu Thr Lys Val Glu Thr Lys Asn Gly Glu Val Pro Ile Gln Ala Leu

50 55 60Lys Ile Ala Arg Thr Tyr Ser Gln Lys Tyr Pro Tyr Thr Tyr Phe Ser65 70 75 80Ala Met Ser Lys Ala Lys Glu Val Leu Cys Glu Lys Gln Ala Phe Glu

85 90 95Gln Ile Lys Gln Glu Asn Gln Asp Tyr Gln Ala Cys Glu Val Asn Gln

100 105 110Lys Tyr Cys Val Tyr Val Glu Ser Lys Asp Phe Leu Lys Asp Phe Lys

115 120 125Arg Phe Lys Ile Gln Asp Val Asp Phe Leu Phe Ser Pro Phe Ser Leu

130 135 140Ile Tyr Asp Phe Val Arg Asp Asn Leu Glu Asn Lys Pro Leu Leu Tyr145 150 155 160Leu Leu Leu Glu Arg Ser Arg Phe Tyr Phe Leu Ile Ala Asp Lys Lys

165 170 175Glu Ile Phe Leu Ala Lys Ser Val Phe Leu Glu Glu Gln Pro Glu Glu

180 185 190Phe Ile Glu Ser Lys Glu Glu Asp Ser Met Gly Met Asp Asn Glu Ala

195 200 205Val Asp Leu Phe Leu Ser Glu Ile Gln Glu Asp Ile Asp Ser Leu Glu

210 215 220Glu Ala Ile Gly Leu Asp Ser Ser Lys Asp Asn Ser Glu Lys Ile Thr225 230 235 240Glu Asp Ala Tyr Ser Leu Ile Glu Gly Met Thr Asn Ile Pro Leu Ile

245 250 255Ala Asp Val Leu Gln Glu Gly Leu Arg Gly Val Tyr His Ser Arg Glu

260 265 270Ile Asp Phe Val Glu Lys Val Val Val Leu Asp Ser Cys Gln Ile His

275 280 285His Lys Ala Leu Met His Leu Gln Glu Thr Leu Met Ile Glu Val Asp

290 295 300Arg Leu Asp Phe Ser Leu Val Glu Arg Leu Asn Val Leu Ala Arg Met305 310 315 320Glu Asn Glu Lys His Ala Phe

325(2) SEQ ID NO 933 information

Sequence properties:

(A) length: 431 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...431

(xi) sequence representation: SEQ ID NO 933 Met Asn Ile Gln Thr Lys Lys Arg Phe Leu Ala Asn Leu Leu Leu Phe 151015 Ser Leu Phe Ser Cys Leu Lys Ala Glu Thr Leu Ser Glu Asp His Gln

20 25 30Ile Leu Leu Ser Ser Asp Ala Phe His Arg Gly Asp Phe Ala Thr Ala

35 40 45Gln Lys Gly Tyr Met Asn Leu Tyr Lys Gln Thr Asn Lys Val Val Tyr

50 55 60Ala Lys Glu Ala Ala Ile Ser Ala Ala Ser Leu Gly Asp Ile Lys Thr65 70 75 80Ala Met His Leu Ala Me5 Leu Tyr Gln Lys Ile Thr Asn Asn Arg Asn

85 90 95Asp Val Ser Ile Asn Lys Ile Leu Val Asp Gly Tyr Ala Gln Met Gly

100 105 110Gln Ile Asp Lys Ala Ile Glu Leu Leu His Lys Ile Arg Lys Glu Glu

115 120 125Lys Thr Ile Ala Thr Asp Asn Val Leu Gly Thr Leu Tyr Leu Thr Gln

130 135 140Lys Arg Leu Asp Lys Ala Phe Pro Leu Leu Asn Lys Phe Tyr Asn Gln145 150 155 160Val His Asp Glu Asp Ser Leu Glu Lys Leu Ile Thr Ile Tyr Phe Leu

165 170 175Gln Asn Arg Lys Lys Glu Gly Leu Asp Leu Leu Gln Ser His Ile Asp

180 185 190Arg Tyr Gly Cys Ser Glu Gln Leu Cys Gln Lys Ala Leu Asn Thr Phe

195 200 205Thr Gln Phe Asn Glu Leu Asp Leu Ala Lys Thr Thr Phe Ala Arg Leu

210 215 220Tyr Glu Lys Asn Pro Ile Val Gln Asn Ala Gln Phe Tyr Ile Gly Val225 230 235 240Leu Ile Leu Leu Lys Glu Phe Asp Lys Ala Gln Gln Ile Ala Glu Leu

245 250 255Phe Pro Phe Asp Arg Arg Leu Leu Leu Asp Leu Tyr Thr Ala Gln Lys

260 265 270Lys Phe Asp Gln Ala Ser Lys Gln Ala Ser Leu Ile Tyr Gln Glu Arg

275 280 285Lys Asp Pro Lys Phe Leu Gly Leu Glu Ala Ile Tyr His Tyr Glu Ser

290 295 300Leu Ser Ala Asn Lys Lys Lys Leu Thr Lys Glu Glu Met Leu Pro Ile305 310 315 320Ile Gln Lys Leu Glu Gln Ala Thr Lys Glu Arg Gln Ala Trp Leu Ala

325 330 335Lys Thr Lys Asp Lys Glu Asp Ala Gln Asp Ala Phe Phe Tyr Asn Phe

340 345 350Leu Gly Tyr Ser Leu Ile Asp Tyr Asp Met Asp Val Lys Arg Gly Met

355 360 365Asp Leu Val Arg Lys Ala Leu Ala Leu Asp Ser Asn Ser Val Leu Tyr

370 375 380Leu Asp Ser Leu Ala Trp Gly Tyr Tyr Lys Leu GLy Asn Cys Leu Glu385 390 395 400Ala Lys Lys Ile Phe Ser Ser Ile Ala Lys Glu Leu Ile Gln Asn Glu

405 410 415Pro Glu Leu Lys Glu His Asn Lys Ile Ile Gln Glu Cys Lys Lys

420425430 (2) SEQ ID NO:934 information

Sequence properties:

(A) length: 414 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...414

(xi) sequence representation: SEQ ID NO 934: Leu Ile Gln Lys Asn Lys Ser Leu Ser Ile Phe Leu Ile Ser Asn Ser 151015 Val Val Phe Leu Gly Lys Ile Ile Leu His Lys Val Phe Ile Met Glu

20 25 30Ala Leu Glu Cys Leu Lys Arg Ile Glu Lys Glu Ser Ile Gln Thr Ile

35 40 45Tyr Ile Asp Pro Pro Tyr Asn Thr Lys Sar Ser Asn Phe Glu Tyr Glu

50 55 60Asp Ala His Ala Asp Tyr Glu Lys Trp Ile Glu Glu His Leu Ile Leu65 70 75 80Ala Lys Ala Val Leu Lys Gln Ser Gly Cys Ile Phe Ile Ser Met Asp

85 90 95Asp Asn Lys Met Ala Glu Val Lys Ile Ile Ala Asn Glu Ile Phe Gly

100 105 110Thr Arg Asn Phe Leu Gly Thr Phe Ile Thr Lys Gln Ala Thr Arg Ser

115 120 125Asn Ala Lys His Ile Asn Ile Thr His Glu Tyr Val Leu Ser Tyr Ala

130 135 140Lys Asn Lys Ala Phe Ala Pro Gly Phe Lys Ile Leu Arg Thr Leu Leu145 150 155 160Pro Ile Tyr Ala Lys Ala Leu Lys Asp Leu Met Arg Thr Ile Lys Asn

165 170 175Val Phe Lys Gln Lys Gly Gln Ala Gln Ala Gln Leu Ile Leu Lys Glu

180 185 190Gln Ile Lys Glu Leu Ser Gln Lys Glu His Phe Asn Phe Leu Lys Asn

195 200 205Tyr Asn Leu Val Asp Glu Lys Gly Glu Ile Tyr Phe Ala Lys Asp Leu

210 215 220Ser Thr Pro Ser Asn Pro Arg Ser Val Ala Ile Gln Glu Ile Asn Leu225 230 235 240Phe Leu Glu Pro Leu Lys Ser Arg Gly Trp Ser Ser Asp Glu Lys Leu

245 250 255Lys Glu Leu Tyr Tyr Gln Asn Arg Leu Ile Phe Lys Asn Asn Arg Pro

260 265 270Tyr Glu Lys Tyr Tyr Leu Lys Glu Ser Gln Asp Asn Cys Leu Ser Val

275 280 285Leu Asp Phe Tyr Ser Arg Gln Gly Thr Lys Asp Leu Glu Lys Leu Gly

290 295 300Leu Lys Gly Leu Phe Lys Thr Pro Lys Pro Val Ala Leu Ile Lys Tyr305 310 315 320Leu Leu Leu Cys Ser Thr Pro Lys Asp Ser Ile Ile Leu Asp Phe Phe

325 330 335Ala Gly Ser Gly Thr Thr Ala Gln Ala Val Ile Glu Val Asn Lys Asp

340 345 350Tyr Tyr Leu Asn Trp Ser Phe Tyr Leu Cys Gln Lys Glu Glu Lys Ile

355 360 365Lys Asn Asn Pro Gln Ala Val Ser Ile Leu Lys Asn Lys Gly Tyr Lys

370 375 380Asn Thr Ile Ser Asp Ile Met Leu Leu Arg Leu Glu Lys Ile Ile Lys385 390 395 400Arg Ser Glu Tyr Glu Ile Leu Lys Thr Lys Ser Ile Leu Phe

405410 (2) SEQ ID NO 935 message

Sequence properties:

(A) length: 166 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...166

(xi) sequence representation: SEQ ID NO 935: Leu Glu Ile Asp Lys Thr Glu Cys Ser Thr Leu Leu Ala Ser Ile Gln 151015 Lys Gln Gln Leu Val Ile Pro Val Val Gly Asn Phe Ser Ala Gly Lys

20 25 30Ser Thr Leu Leu Asn Arg Phe Leu Gly Ser Ser Val Leu Pro Thr Gly

35 40 45lle Thr Pro Glu Thr Ser Leu Ala Thr Glu Leu His Tyr Ser Ala Asn

50 55 60Glu Arg Ile Glu Ala Phe Ser Ser Asn Asp Glu Lys Thr Glu Ser Phe65 70 75 80Glu Leu Asn Glu Gln Ser Phe Glu Ala lle Lys Glu Asn Ala Ala Lys

85 9095Tyr Ser Tyr Leu Lys Val Tyr Leu Asn Asn Glu Ala Leu Lys Asp Ser

100 105 110Ala Pro Leu Val Phe Val Asp Met Pro Gly Phe Asp Ser Pro Ile Ser

115 120 125Ser His Thr His Ala Ile Leu Glu Tyr Leu Glu Arg Gly Val His Phe

130 135 140Val Ile Leu Thr Ser Val Glu Glu Gly Asn Leu Thr Lys Arg Met Val145 150 155 160Arg Glu Leu Lys Thr Phe

165(2) SEQ ID NO 936 information

Sequence properties:

(A) length: 251 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...251

(xi) sequence representation: SEQ ID NO 936: Met Lys Leu Pro Val Val Glu Ser Phe Phe Ser Leu Gln Gly Glu Gly 151015 Lys Arg Ile Gly Lys Pro Ser Leu Phe Leu Arg Leu Gly Gly Cys Asn

20 25 30Leu Ser Cys Lys Gly Phe Asn Cys Lys Thr Leu Phe Asn Asp Glu Ile

35 40 45Leu Thr Gly Cys Asp Ser Leu Tyr Ala Val His Pro Lys Phe Lys Thr

50 55 60Ser Trp Asp Tyr Tyr Asn Glu Pro LysPro Leu Ile Glu Arg Leu Val65 70 75 80Asn Leu Ala Pro Asn Tyr Lys Asp Phe Asp Phe Ile Leu Thr Gly Gly

85 90 95Glu Pro Ser Leu Tyr Phe Asn Asn Pro Ile Leu Leu Ser Val Leu Glu

100 105 110His Phe Tyr His Lys Lys Ile Pro Leu Phe Val Glu Ser Asn Gly Ser

115 120 125Ile Phe Phe Glu Phe Ser Pro Ile Leu Lys Glu Leu His Phe Thr Leu

130 135 140Ser Val Lys Leu Ser Phe Ser Leu Glu Gln Glu Ser Lys Arg Ile Asn145 150 155 160Leu Lys Ala Leu Gln Asn Ile Leu Asn Asn Ala Lys Ser Val His Phe

165 170 175Lys Phe Val Leu Glu Ser Gln Asn Ala Ala His Ser Ile Ala Glu Ile

180 185 190Gln Ser Leu Leu Lys Gln Leu Ser Leu Lys Asn Asn Glu Ile Phe Leu

195 200 205Met Pro Leu Gly Thr Thr Asn Asn Glu Leu Asp Lys Asn Leu Lys Thr

210 215 220Leu Ala Pro Leu Ala Ile Glu His Gly Phe Arg Leu Ser Asp Arg Leu225 230 235 240His Ile Arg Leu Trp Asp Asn Lys Lys Gly Phe

245631 (2) SEQ ID NO 937 information

Sequence properties:

(A) length: 381 amino acid sequence

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...381

(xi) sequence representation: 937: Met Asn Leu Asn Phe Met Pro Leu Leu His Ala Tyr Asn His Val Ser 151015 Ile Asp Phe His Phe Asn Ser Ser Ala Arg Asp Phe Cys Val His Glu SEQ ID NO

20 25 30Val Pro Leu Tyr Glu Phe Ser Asn Thr Gly Glu His Ala Val Ile Gln

35 40 45Val Arg Lys Ser Gly Leu Ser Thr Leu Glu Met Leu Gln Ile Phe Ser

50 55 60Gln Ile Leu Gly Val Lys Ile Ala Glu Leu Gly Tyr Ala Gly Leu Lys65 70 75 80Asp Lys Asn Ala Leu Thr Thr Gln Phe Ile Ser Leu Pro Lys Lys Tyr

85 90 95Ala Pro Leu Leu Glu Lys Asn Thr Ser Asn Phe Gln Glu Arg Asn Leu

100 105 110Lys Ile Leu Ser Leu Asn Tyr His His Asn Lye Ile Lys Leu Gly His

115 120 125Leu Lys Gly Asn Arg Phe Phe Met Arg Phe Lys Lys Met Thr Pro Leu

130 135 140Asn Ala Gln Lys Thr Glu Gln Val Leu Glu Gln Ile Ala Gln Phe Gly145 150 155 160Met Pro Asn Tyr Phe Gly Ser Gln Arg Phe Gly Lys Phe Asn Asp Asn

165 170 175His Lys Glu Gly Leu Lys Ile Leu Gln Asn Glu Thr Lys Phe Ala His

180 185 190Gln Lys Leu Asn Ala Phe Leu Ile Ser Ser Tyr Gln Ser Tyr Leu Phe

195 200 205Asn Ser Leu Leu Ser Lys Arg Leu Glu Ile Ser Lys Ile Ile Ser Ala

210 215 220Phe Ser Val Lys Glu Ser Leu Glu Phe Phe Lys Gln Lys Asn Leu Ser225 230 235 240Val His Ser Asn Ala Leu Lys Ala Leu Lys Asn Gln Ala His Pro Phe

245 250 255Lys Ile Leu Glu Gly Asp Val Met Arg His Tyr Pro Tyr Gly Lys Phe

260 265 270Phe Asp Ala Leu Glu Leu Glu Lys Glu Ser Glu Arg Phe Leu Asn Lys

275 280 285Glu Ala Val Pro Thr Gly Leu Leu Asp Gly Lys Lys Ala Leu Tyr Ala

290 295 300Lys Aan Leu Ser Leu Glu Ile Glu Lys Gly Phe Gln His Asn Leu Leu305 310 315 320Ser Gly His Ala Lys Thr Leu Gly Ser Arg Arg Phe Phe Trp Val Phe

325 330 335Val Glu Asn Ile Thr Ser Gln Tyr Ile Lys Glu Lys Ala Gln Phe Glu

340 345 350Leu Glu Phe Tyr Leu Pro Lys Gly Ser Tyr Ala Ser Ala Leu Leu Lys

355 360 365Glu Ile Lys His Glu Lys Gly Glu Asn Asn Asp Glu Phe

370375380 (2) SEQ ID NO 938 information

Sequence properties:

(A) length: 697 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...697

(xi) sequence representation: SEQ ID NO 938: Leu Gln Asn Phe Val Phe Asn Lys Lys Trp Leu Ile Tyr Ser Ser Leu 151015 Leu Pro Leu Phe Phe Leu Asn Pro Leu Met Ala Glu Asp Asp Gly Phe

20 25 30Phe Met Gly Val Ser Tyr Gln Thr Ser Leu Ala Val Gln Arg Val Asp

35 40 45Asn Ser Gly Leu Asn Ala Ser Gln Asp Ala Ser Thr Tyr Ile ArgGln

50 55 60Asn Ala Ile Ala Leu Glu Ser Ala Ala Val Pro Leu Ala Tyr Tyr Leu65 70 75 80Glu Ala Met Gly Gln Gln Thr Arg Val Leu Met Gln Met Leu Cys Pro

85 90 95Asp Pro Ser Lys Arg Cys Leu Leu Tyr Ala Gly Gly Tyr Gln Asn Gly

100 105 110Gln Asn Asn Asn Gly Asp Thr Gly Asn Asn Pro Pro Arg Gly Asn Val

115 120 125Asn Ala Thr Phe Asp Met Gln Ser Leu Val Asn Asn Leu Asn Lys Leu

130 135 140Thr Gln Leu Ile Gly Glu Thr Leu Ile Arg Asn Pro Glu Asn Leu Pro145 150 155 160Asn Ser Lys Val Phe Asn Val Lys Phe Gly Asn Gln Ser Thr Val Ile

165170 175Ala Leu Pro Glu Gly Leu Ala Asn Thr Met Asp Ala Leu Asn Asn Asp

180 185 190Ile Thr Asn Ala Leu Thr Thr Leu Trp Tyr Asn Gln Thr Leu Thr Asn

195 200 205Lys Ser Phe Ser Thr Pro Ser Asn Thr Ser Val Asn Phe Ser Pro Gln

210 215 220Val Leu Gln His Leu Leu Gln Asp Gly Leu Ala Thr Ala Asn Asn Asn225 230 235 240Gln Thr Ile Cys Ser Thr Gln Asn Gln Cys Thr Ala Thr Asn Glu Ala

245 250 255Lys Ser Ile Ala Gln Asn Ala Gln Asn Ile Phe Gln Ala Leu Met Gln

260 265 270Aia Gly Ile Leu Gly Gly Leu Ala Asn Glu Lys Gln Phe Gly Phe Thr

275 280 285Tyr Asn Lys Ala Pro Asn Gly Ser Asp Ser Gln Gln Gly Tyr Gln Ser

290 295 300Phe Ser Gly Pro Gly Tyr Tyr Thr Lys Asn Asp Asn Thr Thr Gln Ala305 310 315 320Pro Leu Lys Ala Leu Pro Ala Gly Ala Thr Ile Gly Ser Gly Asn Gly

325 330 335Gln Tyr Thr Tyr His Pro Ser Ser Ala Val Tyr Tyr Leu Ala Asp Ser

340 345 350Ile Ile Ala Asn Gly Ile Thr Ala Ser Met Ile Phe Ser Gly Met Gln

355 360 365Asn Phe Ala Asn Lys Ala Ala Lys Leu Ile Gly Thr Ser Ser Tyr Asn

370 375 380Gln Met Gln Asp Val Ile Asn Tyr Gly Glu Ser Leu Leu Ser Asn Thr385 390395 400Val Ala Tyr Gly Asp Phe Ile Thr Asn Trp Val Ala Pro Tyr Leu Asp

405 410 415Leu Asn Asn Lys Gly Leu Asn Phe Leu Pro Asn Tyr Gly Gly Gln Leu

420 425 430Asn Gly Ala Asn Asn Gln Thr Pro Gln Leu Thr Pro Gln Gln Ala Gln

435 440 445Gln Glu Gln Lys Val Ile Met Asn Gln Leu Glu Gln Ala Thr Asn Ala

450 455 460Pro Thr Pro Ala Gln Ile Asn Arg Ile Leu Ala Asn Pro Tyr Ser Pro465 470 475 480Thr Ala Lys Thr Leu Met Ala Tyr Gly Leu Tyr Arg Ser Lys Ala Val

485 490 495Ile Gly Gly Val Ile Asp Glu Met Gln Thr Lys Val Asn Gln Val Tyr

500 505 510Gln Met Gly Phe Ala Arg Asn Phe Leu Glu His Asn Ser Asn Ser Asn

515 520 525Asn Met Asn Gly Phe Gly Val Lys Met Gly Tyr Lys Gln Phe Phe Gly

530 535 540Lys Lys Arg Met Phe Gly Leu Arg Tyr Tyr Gly Phe Tyr Asp Phe Gly545 550 555 560Tyr Ala Gln Phe Gly Thr Glu Ser Ser Leu Val Lys Ala Thr Leu Ser

565 570 575Ser Tyr Gly Ala Gly Thr Asp Phe Leu Tyr Asn Val Phe Thr Arg Lys

580 585 590Arg Gly Thr Glu Ala Ile Asp Ile Gly Phe Phe Ala Gly Ile Gln Leu

595 600 605Ala Gly Gln Thr Trp Lys Thr Asn Phe Leu Asp Gln Val Asp Gly Asn

610615 620His Leu Lys Pro Lys Asp Thr Ser Phe Gln Phe Leu Phe Asp Leu Gly625 630 635 640Ile Arg Thr Asn Phe Ser Lys Ile Ala His Gln Lys Arg Ser Arg Phe

645 650 655Ser Gln Gly Ile Glu Phe Gly Leu Lys Ile Pro Val Leu Tyr His Thr

660 665 670Tyr Tyr Gln Ser Glu Gly Val Thr Ala Lys Tyr Arg Arg Ala Phe Ser

675 680 685Phe Tyr Val Gly Tyr Asn Ile Gly Phe

690695 (2) SEQ ID NO 939 information

Sequence properties:

(A) length: 697 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...697

(xi) sequence representation: 939: Leu Gln Asn Phe Val Phe Asn Lys Lys Trp Leu Ile Tyr Ser Ser Leu 151015 Leu Pro Leu Phe Phe Leu Asn Pro Leu Met Ala Glu Asp Asp Gly Phe SEQ ID NO

10 25 30Phe Met Gly Val Ser Tyr Gln Thr Ser Leu Ala Val Gln Arg Val Asp

35 40 45Asn Ser Gly Leu Asn Ala Ser Gln Asp Ala Ser Thr Tyr Ile Arg Gln

5055 60Asn Ala Ile Ala Leu Glu Ser Ala Ala Val Pro Leu Ala Tyr Tyr Leu65 70 75 80Glu Ala Met Gly Gln Gln Thr Arg Val Leu Met Gln Met Leu Cys Pro

85 90 95Asp Pro Ser Lys Arg Cys Leu Leu Tyr Ala Gly Gly Tyr Gln Asn Gly

100 105 110Gln Asn Asn Asn Gly Asp Thr Gly Asn Asn Pro Pro Arg Gly Asn Val

115 120 125Asn Ala Thr Phe Asp Met Gln Ser Leu Val Asn Asn Leu Asn Lys Leu

130 135 140Thr Gln Leu Ile Gly Glu Thr Leu Ile Arg Asn Pro Glu Asn Leu Pro145 150 155 160Asn Ser Lys Val Phe Asn Val Lys Phe Gly Asn Gln Ser Thr Val Ile

165 170 175Ala Leu Pro Glu Gly Leu A1a Asn Thr Met Asp Ala Leu Asn Asn Asp

180 185 190Ile Thr Asn Ala Leu Thr Thr Leu Trp Tyr Asn Gln Thr Leu Thr Asn

195 200 205Lys Ser Phe Ser Thr Pro Ser Asn Thr Ser Val Asn Phe Ser Pro Gln

210 215 220Val Leu Gln His Leu Leu Gln Asp Gly Leu Ala Thr Ala Asn Asn Asn225 230 235 240Gln Thr Ile Cys Ser Thr Gln Asn Gln Cys Thr Ala Thr Asn Glu Ala

245 250 255Lys Ser Ile Ala Gln Asn Ala Gln Asn Ile Phe Gln Ala Leu Met Gln

260 265 270Ala Gly Ile Leu Gly Gly Leu Ala Asn Glu Lys Gln Phe Gly Phe Thr

275280 285Tyr Asn Lys Ala Pro Asn Gly Ser Asp Ser Gln Gln Gly Tyr Gln Ser

290 295 300Phe Ser Gly Pro Gly Tyr Tyr Thr Lys Asn Asp Asn Thr Thr Gln Ala305 310 315 320Pro Leu Lys Ala Leu Pro Ala Gly Ala Thr Ile Gly Ser Gly Asn Gly

325 330 335Gln Tyr Thr Tyr His Pro Ser Ser Ala Val Tyr Tyr Leu Ala Asp Ser

340 345 350Ile Ile Ala Asn Gly Ile Thr Ala Ser Met Ile Phe Ser Gly Met Gln

355 360 365Asn Phe Ala Asn Lys Ala Ala Lys Leu Ile Gly Thr Ser Ser Tyr Asn

370 375 380Gln Met Gln Asp Val Ile Asn Tyr Gly Glu Ser Leu Leu Ser Asn Thr385 390 395 400Val Ala Tyr Gly Asp Phe Ile Thr Asn Trp Val Ala Pro Tyr Leu Asp

405 410 415Leu Asn Asn Lys Gly Leu Asn Phe Leu Pro Asn Tyr Gly Gly Gln Leu

420 425 430Asn Gly Ala Asn Asn Gln Thr Pro Gln Leu Thr Pro Gln Gln Ala Gln

435 440 445Gln Glu Gln Lys Val Ile Met Asn Gln Leu Glu Gln Ala Thr Asn Ala

450 455 460Pro Thr Pro Ala Gln Ile Asn Arg Ile Leu Ala Asn Pro Tyr Ser Pro465 470 475 480Thr Ala Lys Thr Leu Met Ala Tyr Gly Leu Tyr Arg Ser Lys Ala Val

485 490 495Ile Gly Gly Val Ile Asp Glu Met Gln Thr Lys Val Asn Gln Val Tyr

500 5C5510Gln Met Gly Phe Ala Arg Asn Phe Leu Glu His Asn Ser Asn Ser Asn

515 520 525Asn Met Asn Gly Phe Gly Val Lys Met Gly Tyr Lys Gln Phe Phe Gly

530 535 540Lys Lys Arg Met Phe Gly Leu Arg Tyr Tyr Gly Phe Tyr Asp Phe Gly545 550 555 560Tyr Ala Gln Phe Gly Thr Glu Ser Ser Leu Val Lys Ala Thr Leu Ser

565 570 575Ser Tyr Gly Ala Gly Thr Asp Phe Leu Tyr Asn Val Phe Thr Arg Lys

580 585 590Arg Gly Thr Glu Ala Ile Asp Ile Gly Phe Phe Ala Gly Ile Gln Leu

595 600 605Ala Gly Gln Thr Trp Lys Thr Asn Phe Leu Asp Gln Val Asp Gly Asn

610 615 620His Leu Lys Pro Lys Asp Thr Ser Phe Gln Phe Leu Phe Asp Leu Gly625 630 635 640Ile Arg Thr Asn Phe Ser Lys Ile Ala His Gln Lys Arg Ser Arg Phe

645 650 655Ser Gln Gly Ile Glu Phe Gly Leu Lys Ile Pro Val Leu Tyr His Thr

660 665 670Tyr Tyr Gln Ser Glu Gly Val Thr Ala Lys Tyr Arg Arg Ala Phe Ser

675 680 685Phe Tyr Val Gly Tyr Asn Ile Gly Phe

690695 (2) information of SEQ ID NO:940

Sequence properties:

(A) length: 1237 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1237

(xi) sequence representation: 940 SEQ ID NO: Met Ile Lys Lys Ala Lys Lys Phe Ile Pro Leu Phe Leu Ile Gly Ser 151015 Leu Leu Ala Glu Asp Asn Gly Trp Tyr Met Ser Val Gly Tyr Gln Ile

20 25 30Gly Gly Thr Gln Gln Phe Ile Asn Asn Lys Gln Leu Leu Glu Asn Gln

35 40 45Asn Ile Ile Asn Ser Ile Thr Gln Ser Ala Ile Asn Ile Ala Gly Pro

50 55 60Thr Thr Gly Leu Ile Thr Leu Ser Ser Gln Ser Val Ile Asp Ala Leu65 70 75 80Gly Tyr Gly Val Ser Asn Thr Val Gly Asn Gln Leu Glu Gly Ile Ser

85 90 95Ash Ile Leu Asn Gln Ile Gly Lys Arg Lys Asp Phe Tyr Ser Ser Arg

100 105 110Gln Ile Ser Ser Ile Ser Gln Gln Ile Ile Gly Leu Lys Gly Ser Ser

115 120 125Asp Pro Leu Lys Ala His Ser Ser Gln Ile Thr Ala Lys Leu Leu Ser

130 135 140Asn Thr Gln Ser Ala Phe Asp Gln Gly Ile Ala Leu Ser Ser Asn Ile145 150 155 160Ile Ser Ala Val Asn Ser Leu Asn Pro Ser Asn Asn Ser Gln Glu Val

165 170 175Lys Ala Gln Leu Gln Asn Thr Ala Gln Ser MetThr Glu Leu Leu Gln

180 185 190Gln Ile Glu His Ser Ile Thr Lys Thr Thr Ser Thr Thr Tyr Ala Gln

195 200 205Ser Leu Leu Ser Asn Leu Thr Asp Ala Val Asn Ala Ser Ser Asn Asn

210 215 220Thr Thr Tyr Val Ser Ala Leu Val Asn Ala Leu Asn Thr Leu Gly Val225 230 235 240Gly Val Phe Pro Thr Thr Thr Ser Thr His Val Val Leu Asn Pro Pro

245 250 255Gly Gln Val Val Phe Tyr Pro Thr Asn Ser Leu Leu Gly Ser Thr Ser

260 265 270Ser Asn Ser Asn Asn Gln Gln Gln Tyr Asn Asn Thr Leu Leu Met Asn

275 280 285Thr Leu Gln Gly Glu Leu Ser Thr Asn Asn Gln Asn Asn Pro Asn Gly

290 295 300Cys Ala Asn Gln Ile Gln Cys Leu Glu Gln Phe Ile Gln Asn Leu Thr305 310 315 320Pro Leu Ala Ala Thr Pro Thr Ser Thr Asn Gln Ala Asn Gln Gln Val

325 330 335Gln Ala Ile Ala Gln Lys Leu Gln Ser Val Ala Ile Asn Ala Leu Asp

340 345 350Asn Asn Ala Ile Asn Asn Thr Thr Tyr Asn Leu Asn Asn Leu His Asn

355 360 365Ala Leu Asn Phe Gln Ala Tyr Gln Ser Thr Ile Glu Gln Tyr Asn Asn

370 375 380Ala Leu Lys Gln Ile Ser Trp Ile Ser Phe Ser Glu Pro Lys Asn Leu385 390 395 400Leu Lys Asn Thr Ser Asn Asn Tyr Gln Ile GlyThr Val Thr Asn Asp

405 410 415Gln Gly Gln Asn Ile Ser Ala Tyr Asp Cys Thr Ser Ala Thr Gly Ser

420 425 430Leu Ser Ser Asp Ala Ser Ser Gly Ile Ser Cys Ser Ala Thr Ser Ser

435 440 445Thr Asn Asn Thr Asn Ser Phe Asp Asn Ser Leu Val Ala Thr Ser Lys

450 455 460Val Gln Thr Ile Asn Gly Lys Glu Gln Ile Gly Val Asn Ser Phe Asn465 470 475 480Leu Val Ser Gln Val Trp Ser Val Tyr Asn Ser Leu Lys Thr Ser Glu

485 490 495Glu Asn Leu Gln Lys Asn Ala Lys Ile Leu Cys Asn Asn Gly Ser Gln

500 505 510Ser Gly Thr Ser Pro Cys Asn Ser Ser Ser Gly Gly Leu Ser Ile Ser

515 520 525Gly Asn Ala Gln Leu Gln Asn Ile Leu Ser Pro Thr Asn Gly Thr Thr

530 535 540Thr Asn Thr Glh Ala Lys Ser Asn Ala Ser Lys Leu Lys Ala Met Val545 550 555 560Met Val Asn Asn Glu Glu Glu Ala Lys Thr Thr Asn Phe Asn Gln Ser

565 570 575Ser Gly Pro Thr Thr Gln Ser Ser Asn Ser Thr Val Met Gly Ala Leu

580 585 590Asn Thr Va1 Leu Gln Asn Val Ser Asn Phe Gln Gln Ser Ile Gln Sar

595 600 605Ala Phe Gln Asn Gln Glu Asn Asn Ile Gln Ala Trp Ala Asn Ala Leu

610 615 620Tyr Asn Thr Ser Asn Pro Asn Gly Asn Gln Ser Gln Asn Leu Thr Thr625 630 635 640Asn Asn Asn Gln Asp Leu Arg Ile Gln Leu Arg Ala Asn Phe Tyr Gln

645 650 655 Leu Ile Ash Thr Ile Asn Gln Gln Val Pro Thr Asp Met Asn Ala Leu

660 665 670Ile Asn Gln Ser Gln Gln Thr Gln Gln Thr Ser Gly Ser Ala Ser Thr

675 680 685Thr Asn Asn Ala Cys Ala Ser Gly Met Gly Ser Ser Gly Asn Trp Cys

690 695 700Tyr Gln Gln Trp Ser Asp Ser Lys Ala Tyr Tyr Ser Gly Leu Gln Ser705 710 715 720Ala Leu Gly Tyr Gln Thr Gln Ala Thr Thr Gln Asn Gly Ser Ser Gly

725 730 735Gly Ser Asn Ile Thr Tyr Asn Val Gln Gln Ile Thr Leu Thr Ser Gly

740 745 750Gly Leu Leu Asn Gln Ile Ile Thr Asn Leu Lys Ser Val Asn Gly Gly

755 760 765Ser Asn Gly Gly Ser Ser Gly Asn Gly Thr Ser Gln Ile Asn Thr Ala

770 775 780Tyr Gln Met Leu Thr Asp Ala Ser Asp Gly Lys Leu Gly Thr Tyr Asn785 790 795 800Ser Ser Asn Ser Ser Asn Ser Ser Asn Ser Gly Asn Asn Asn Gly Tyr

805 810 815Thr Pro Cys Asn Ser Thr Asn Gly Ser Asn Gly Thr Ser Gly Ser Asn

820 825 830Cys Tyr Glu Pro Asn Lys Gln Gln Asn Ala Thr Thr Ala Thr Thr Thr

835 840 845Thr Asp Ser Asn Leu Gln Lys Val Tyr Asn Asp Ala Gln Lys Ile Ala

850 855 860Asn Ile Ile Ala Ser Ser Gly Asn Asn Lys Gly Val Glu Asn Gly Leu865 870 875 880Lys Gln Phe Phe Glu Ala Leu Lys Ser Asn Ser Ser Ser Leu Ser Asn

885 890 895Leu Cys Gly Asn Gly Ser Ser Gly Ser Ser Ser Thr Cys Ser Gly Gly

900 905 910Leu Ile Asn Leu Leu Gly Ala Ile Pro Thr Asn Gly Val Ser Asp Thr

915 920 925Asn Asn Leu Ile Asn Leu Leu Thr Glu Phe Ile Lys Thr Ala Gly Phe

930 935 940Ile Gln Asn Asn Asp Ser ASn Val Ser Thr Ser Leu Thr Ser Ala Phe945 950 955 960Gln Ala Ile Thr Ser Ala Ile Ser Gln Gly Phe Gln Ala Leu Gln Asn

965 970 975Asp Ile Ser Pro Asn Ala Ile Leu Thr Leu Leu Gln Glu Ile Thr Ser

980 985 990Asn Thr Thr Thr Ile Gln Ser Phe Ser Gln Thr Leu Arg Gln Leu Leu

995 1000 1005Gly Asp Lys Thr Phe Phe Met Val Gln Gln Lys Leu Ile Asp Ala Met

1010 1015 1020Ile Asn Ala Arg Asn Gln Val Gln Asn Ala Gln Asn Gln Ala Asn Asn1025 1030 1035 1040Tyr Gly Ser Gln Pro Val Leu Ser Gln Tyr Ala Ala Gly Lys Ser Thr

1045 1050 1055Gln His Gly Met Ser Asn Gly Leu Gly Val Gly Ile Gly Tyr Lys Tyr

1060 1065 1070Phe Phe Gly Lys Ala Arg Lys Leu Gly LeuArg His Tyr Phe Phe Phe

1075 1080 1085Asp Tyr G1y Phe Ser Glu Ile Gly Leu Ala Asn Gln Ser Val Lys Ala

1090 1095 1100Asn Ile Phe Ala Tyr Gly Val Gly Thr Asp Phe Leu Trp Asn Leu Phe1105 1110 1115 l120Arg Arg Thr Tyr Asn Thr Lys Ala Leu Asn Phe Gly Leu Phe Ala Gly

1125 1130 1135Val Gln Leu Gly Gly Ala Thr Trp Leu Ser Ser Leu Arg Gln Gln Ile

1140 1145 1150Ile Asp Asn Trp Gly Asn Ala Asn Asp Ile His Ser Thr Asn Phe Gln

1155 1160 1165Val Ala Leu Asn Phe Gly Val Arg Thr Asn Phe Ala Glu Phe Lys Arg

1170 1175 1180Phe Ala Lys Lys Phe His Asn Gln Gly Val Ile Ser Gln Lys Ser Val1185 1190 1195 1200Glu Phe Gly Ile Lys Val Pro Leu Ile Asn Gln Ala Tyr Leu Asn Ser

1205 1210 1215Ala Gly Ala Asp Val Ser Tyr Arg Arg Leu Tyr Thr Phe Tyr Ile Asn

1220 1225 1230Tyr Ile Met Gly Phe

1235(2) SEQ ID NO 941 information

Sequence properties:

(A) length: 171 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1.. 17l

(xi) sequence representation: SEQ ID NO 941: Met Glu Lys Leu Pro Lys Lys Arg Val Ser Lys Thr Lys Ser Gln Lys 151015 Leu Ile His Ser Leu Thr Thr Gln Lys Asn Arg Ala Phe Leu Gln Lys

20 25 30Thr Ser Ala Asn Glu Met Leu Leu Glu Leu Glu Lys Gly Ala Phe Lys

35 40 45Lys Asn Glu Ala Tyr Phe Ile Ser Asp Glu Glu Asp Lys Asn Tyr Val

50 55 60Leu Val Pro Asp Asn Val Ile Ser Leu Leu Ala Glu Asn Ala Arg Lys65 70 75 80Ala Phe Glu Ala Arg Leu Arg Ala Glu Leu Glu Arg Asp Ile Ile Thr

85 90 95Gln Ala Pro Ile Asp Phe Glu Asp Val Arg Glu Val Ser Leu Gln Leu

100 105 110Leu Glu Asn Leu Arg Gln Lys Asp Gly Asn Leu Pro Asn Ile Asn Thr

115 120 125Leu Asn Phe Val Lys Gln Ile Lys Lys Glu His Pro Asn Leu Phe Phe

130 135 140Asn Phe Asp Asn Met Phe Lys Gln Pro Pro Phe Asn Glu Asn Asn Phe145 150 155 160Glu Asn Phe Asp Asn Ser Asp Glu Glu Asn Phe

165170 (2) information of SEQ ID NO 942

Sequence properties:

(A) length: 435 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...435

(xi) sequence representation: 942: Met Lys Lys Ile Leu Ile Thr Leu Ile Thr Leu Leu Leu Gly Val Phe 151015 Met Gly Leu Gln Ala Ser Ala Leu Thr His Gln Glu Ile Asn Gln Ala

20 25 30Lys Val Pro Val Ile Tyr Glu Glu Asn His Leu Leu Pro Met Gly Phe

35 40 45Ile His Leu Ala Phe Arg Gly Gly Gly Ser Leu Ser Asp Lys Asn Gln

50 55 60Leu Gly Leu Ala Lys Leu Phe Ala Gln Val Leu Asn Glu Gly Thr Lys65 70 75 80Glu Leu Gly Ala Val Gly Phe Ala Gln Leu Leu Glu Gln Lys Ala Ile

85 90 95Ser Leu Asn Val Asp Thr Ser Ala Glu Asp Leu Gln Ile Thr Leu Glu

100 105 110Phe Leu Lys Glu Tyr Glu Asp Glu Ala Ile Met Arg Leu Lys Glu Leu

115 120 125Leu Lys Ser Pro Asn Phe Thr Gln Asn Ala Leu Glu Lys Val Lys Thr

130 135 140Arg Met Leu Ala Gln Leu Leu Gln Lys Glu Ser Asp Phe Asp Tyr Leu145 150 155 160Ala Lys Leu Thr Leu Lys Gln Glu Leu Phe Ala Asn Thr Pro Leu Ala

165 170 175Asn Ala Ala Leu Gly Thr Lys Glu Ser Leu Gln Lys Ile Lys Leu Asp

180 185 190Asp Leu Lys Gln Gln Phe Ala Lys Val Phe Glu Leu Asn Lys Leu Val

195 200 205Val Val Leu Gly Gly Asp Leu Lys Val Asn Gln Thr Leu Asn Arg Leu

210 215 220Asn Asn Ala Leu Asn Phe Leu Pro Gln Gly Lys Ala Tyr Glu Glu Pro225 230 235 240Tyr Phe Glu Ala Ser Asp Lys Lys Ser Glu Lys Val Leu Tyr Lys Asp

245 250 255Thr Glu Gln Ala Phe Val Tyr Phe Gly Val Pro Phe Lys Ile Lys Asp

260 265 270Leu Lys Gln Asp Leu Ala Lys Ser Lys Val Met Met Phe Val Leu Gly

275 280 285 G1y G1y Phe Gly Ser Arg Leu Met Glu Lys Ile Arg Val Gln Glu Gly

290 295 300Leu Ala Tyr Ser Val Tyr Ile Arg Ser Asn Phe Ser Lys Val Ala His305 310 315 320Phe Ala Ser Gly Tyr Leu Gln Thr Lys Leu Ser Thr Gln Ala Lys Ser

325 330 335Val Ala Leu Val Lys Lys Ile Ile Lys Glu Phe Ile Glu Lys Gly Met

340 345 350Thr Gln Gln Glu Leu Asp Asp Ala Lys Lys Phe Leu Leu Gly Ser Glu

355 360 365Pro Leu Arg Asn Glu Thr Ile Ser Ser Arg Leu Asn Thr Thr Tyr Asn

370 375 380Tyr Phe Tyr Leu Gly Leu Pro Leu Asp Phe Asn Gln Thr Leu Leu Asn385 390 395 400Gln Ile Gln Lys Met Ser Leu Lys Glu Ile Asn Asp Phe Ile Lys Glu

405 410 415His Thr Glu Ile Asn Asp Leu Thr Phe Ala Ile Val Ser Asn Lys Lys

420 425 430Lys Asp Lys

435(2) SEQ ID NO 943 message

Sequence properties:

(A) length: 614 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...614

(xi) sequence representation: SEQ ID NO 943 Leu Ala Ser Pro Lys Glu Thr Pro Lys Glu Ala Gln Lys Asn Glu Ala 151015 Gln Asn Glu Thr Ser Gln Ser Asn Gln Thr Pro Lys Glu Met Lys Val

20 25 30Lys Ser Ile Ser Tyr Val Gly Leu Ser Tyr Met Ser Asp Met Leu Ala

35 40 45Asn Glu Ile Ala Lys Ile Arg Val Gly Asp Met Val Asp Ser Lys Lys

50 55 60Ile Asp Thr Ala Val Leu Ala Leu Phe Asn Gln Gly Tyr Phe Lys Asp65 70 75 80Val Tyr Ala Thr Phe Glu Asn Gly Ile Leu Glu Phe His Phe Asp Glu

85 90 95Lys Ala Arg Ile Ala Gly Val Glu Ile Lys Gly Tyr Gly Thr Glu Lys

100 105 110Glu Lys Asp Gly Leu Lys Ser Gln Met Gly Ile Lys Lys Gly Asp Thr

115 120 125Phe Asp Glu Gln Lys Leu Glu His Ala Lys Thr Ala Leu Lys Thr Ala

130 135 140Leu Glu Gly Gln Gly Tyr Tyr Gly Ser Val Val Glu Val Arg Thr Glu145 150 155 160Lys Val Ser Glu Gly Ala Leu Leu Ile Val Phe Asp Val Asn Arg Gly

165 170 175Asp Ser Ile Tyr Ile Lys Gln Ser Ile Tyr Glu Gly Ser Asp Lys Leu

180 185 190Lys Arg Arg Val Ile Glu Ser Leu Ser Ala Asn Lys Gln Arg Asp Phe

195 200 205Met Gly Trp Met Trp Gly Leu Asn Asp Gly Lys Leu Arg Leu Asp Gln

210 215 220Leu Glu Tyr Asp Ser Leu Arg Ile Gln Asp Val Tyr Met Arg Arg Gly225 230 235 240Tyr Leu Asp Ala His Ile Ser Ser Pro Phe Leu Lys Thr Asp Phe Ser

245 250 255Thr His Asp Ala Lys Leu His Tyr Lys Val Lys Glu Gly Ile Gln Tyr

260 265 270Arg Ile Ser Asp Ile Leu Ile Glu Ile Asp Asn Pro Val Val Pro Leu

275 280 285Lys Thr Leu Glu Lys Ala Leu Lys Val Lys Arg Lys Asp Val Phe Asn

290 295 300Ile Glu His Leu Arg Ala Asp Ala Gln Ile Leu Lys Thr Glu Ile Ala305 310 315 320Asp Lys Gly yr Ala Phe Ala Val Val Lys Pro Asp Leu Asp Lys Asp

325 330 335Glu Lys Asn Gly Leu Val Lys Val Ile Tyr Arg Ile Glu Val Gly Asp

340 345 350Met Val His Ile Asn Asp Val Ile Ile Ser Gly Asn Gln Arg Thr Ser

355 360 365Asp Arg Ile Ile Arg Arg Glu Leu Leu Leu Gly Pro Lys Asp Lys Tyr

370 375 380Asn Leu Thr Lys Leu Arg Asn Ser Glu Asn Ser Leu Arg Arg Leu Gly385 390 395 400Phe Phe Ser Lys Val Lys Ile Glu Glu Lys Arg Val Asn Ser Ser Leu

405 410 415Met Asp Leu Leu Val Ser Val Glu Glu Gly Arg Thr Gly Gln Leu Gln

420 425 430Phe Gly Leu Gly Tyr Gly Ser Tyr Gly Gly Leu Met Leu Asn Gly Ser

435 440 445Val Ser Glu Arg Asn Leu Phe Gly Thr Gly Gln Ser Met Ser Leu Tyr

450 455 460Ala Asn Ile Ala Thr Gly Gly Gly Arg Sar Tyr Pro Gly Met Pro Lys465 470 475 480Gly Ala Gly Arg Met Phe Ala Gly Asn Leu Ser Leu Thr Asn Pro Arg

485 490 495Ile Phe Asp Ser Trp Tyr Ser Ser Thr Ile Asn Leu Tyr Ala Asp Tyr

500 505 510Arg Ile Ser Tyr Gln Tyr Ile Gln Gln Gly Gly Gly Phe Gly Val Asn

515 520 525Val Gly Arg Met Leu Gly Asn Arg Thr His Val Ser Leu Gly Tyr Asn

530 535 540Leu Asn Val Thr Lys Leu Leu Gly Phe Ser Ser Pro Leu Tyr AsnArg545 550 555 560Tyr Tyr Ser Ser Val Asn Glu Val Ala Ser Pro Arg Gln Cys Ser Thr

565 570 575Pro Ala Ser Val Ile Ile Asn Arg Leu Ser Gly Gly Arg Thr Pro Leu

580 585 590Val Pro Glu Ser Cys Ser Ser Pro Gly Ala Ile Thr Ile Phe Thr Arg

595 600 605Asn Lys Arg Tyr Leu Gly

610(2) SEQ ID NO 944 information

Sequence properties:

(A) length: 376 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...376

(xi) Sequence representation: SEQ ID NO 944: Leu Cys Glu Gly Pro Asn Val Met Ser Gly Trp Lys Pro His Ile Lys 151015 His Gly Val Tyr Arg Asn Trp Asn Asn Trp Arg Asn Asn Tyr Thr Ala

20 25 30Val Tyr Leu Ser Asp Arg Ile Glu Ala Trp Asp Gly Arg Phe Phe Ile35 40 45Val Pro G1y Leu Arg Tyr Ala Phe Val Gln Tyr Asn Asn Glu Asn Ala

50 55 60Ser Asn Trp Met Gln Ile Pro Glu Lys Asp Leu Arg Lys Ile Lys His65 70 75 80Met Asn Asn Trp Met Pro Ser Thr Asn Ile Gly Phe Ile Pro Val Gln

85 90 95Gly Asp His Asn Val Leu Thr Tyr Phe Asn Tyr Gln Arg Ser Phe Val

100 105 110Pro Pro Gln Leu Asp Val Leu Ser Tyr Gly Gly Ala Glu Tyr Phe Thr

115 120 125Gln His Phe Asp Thr Val Glu Ala Gly Ala Arg Tyr Thr Tyr Lys Asp

130 135 140Lys Phe Ser Phe Asn Ala Asp Tyr Phe Arg Ile Trp Ala Arg Asp Phe145 150 155 160Ala Thr Gly Gln Tyr Ser Val Tyr Thr Ser Gly Pro Met Lys Gly Asn

165 170 175Val Arg Pro Ile Asn Gly Tyr Ser Gln Gly Val Glu Leu Glu Leu Tyr

180 185 190Tyr Arg Pro Ile Arg Gly Leu Gln Phe His Ala Ala Phe Asn Tyr Ile

195 200 205Asp Thr Arg Val Thr Ser His Gly Pro Leu Thr Asp Leu Asn Gly Asp

210 215 220Val Leu Lys Gly Thr Ser Tyr Asn Lys His Phe Pro Phe Val Ser Pro225 230 235 240Phe Gln Phe Ile Phe Asp Ala Arg Tyr Asn Trp Arg Lys Thr Thr Ile

245 250 255Gly lle Ser Ser Tyr Phe Tyr Ser Arg Ala Tyr Ser Gly Ile Ser Asn

260 265 270Ser Ala Ala Gly Gly Tyr Tyr Gly Met Gln Tyr Tyr Ser Gly Gly Asn

275 280 285Asn Tyr Glu Ser Val Leu Asn Ser Gly Tyr Gln Cys Glu Ala Trp Cys

290 295 300Met Thr GlnHis Glu Gly Leu Leu Pro Trp Tyr Trp Val Trp Asn Ile305 310 315 320Gln Val Ser Gln lle Phe Trp Glu Asn Gly Arg His Arg Val Thr Gly

325 330 335Ser Leu Gln Ile Asn Asn Ile Phe Asn Met Lys Tyr Tyr Phe Thr Gly

340 345 350Ile Gly Ser Ser Pro Ala Gly Leu Gln Pro Ala Pro Gly Arg Ser Val

355 360 365Thr Ala Tyr Leu Asn Tyr Thr Phe

370375 (2) SEQ ID NO 945 information

Sequence properties:

(A) length: 621 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...621

(xi) sequence representation: 945 SEQ ID NO: Leu His Ala Glu Asp Asn Gly Phe Phe Val Ser Ala Gly Tyr Gln Ile 151015 Gly Glu Ala Val Gln Met Val Lys Asn Thr Gly Glu Leu Lys Asn Leu

20 25 30Asn Asp Lys Tyr Glu Gln Leu Ser Gln Ser Leu Ala Gln Leu Ala Ser

35 40 45Leu Lys Lys Ser Ile Gln Thr Ala Asn Asn Ile Gln Ala Val Asn Asn

50 55 60Ala Leu Ser Aap Leu Lys Ser Phe Ala SerAsn Asn His Thr Asn Lys65 70 75 80Glu Thr Ser Pro Ile Tyr Asn Thr Ala Gln Ala Val Ile Thr Ser Val

85 90 95Leu Ala Phe Trp Ser Leu Tyr Ala Gly Asn Ala Leu Ser Phe His Val

100 105 110Thr Gly Leu Asn Asp Gly Ser Asn Ser Pro Leu Gly Arg Ile His Arg

115 120 125Asp Gly Asn Cys Thr Gly Leu Gln Gln Cys Phe Met Ser Lys Glu Thr

130 135 140 Tyr Asp Lys Met Lys Thr Leu Ala Glu Asn Leu Gln Lys Ala Gln Gly 145 150 155 160Asn Leu Cys Ala Leu Ser Glu Cys Ser Ser Asn Gln Ser Asn Gly Gly

165 170 175Lys Thr Ser Met Thr Thr Ala Leu Gln Thr Ala Gln Gln Leu Met Asp

180 185 190Leu Ile Glu Gln Thr Lys Val Ser Met Val Trp Lys Asn Ile Val Ile

195 200 205Ala Gly Val Thr Asn Lys Pro Asn Gly Ala Gly Ala Ile Thr Ser Thr

210 215 220Gly His Val Thr Asp Tyr Ala Val Phe Asn Asn Ile Lys Ala Met Leu225 230 235 240Pro Ile Leu Gln Gln Ala Leu Thr Leu Ser Gln Ser Asn His Thr Leu

245 250 255Ser Thr Gln Leu Gln Ala Arg Ala Met Gly Ser Gln Thr Asn Arg Glu

250 265 270Phe Ala Lys Asp Ile Tyr Ala Leu Ala Gln Asn Gln Lys Gln Ile Leu

275 280 285Ser Asn Ala Ser Ser Ile Phe Asn Leu Phe Asn Ser IlePro Lys Asp

290 295 300Gln Leu Lys Tyr Leu Glu Asn Ala Tyr Leu Lys Val Pro His Leu Gly305 310 315 320Lys Thr Pro Thr Asn Pro Tyr Arg Gln Asn Val Asn Leu Asn Lys Glu

325 330 335Ile Asn Ala Val Gln Asp Asn Val Ala Asn Tyr Gly Asn Arg Leu Asp

340 345 350Ser Ala Leu Ser Val Ala Lys Asp Val Tyr Asn Leu Lys Ser Asn Gln

355 360 365Thr Glu Ile Val Thr Thr Tyr Asn Asp Ala Lys Asn Leu Ser Glu Glu

370 375 380Ile Ser Lys Leu Pro Tyr Asn Gln Val Asn Val Thr Asn Ile Val Met385 390 395 400Ser Pro Lys Asp Ser Thr Ala Gly Gln Tyr Gln Ile Asn Pro Glu Gln

405 410 415Gln Ser Asn Leu Asn Gln Ala Leu Ala Ala Met Ser Asn Asn Pro Phe

420 425 430Lys Lys Val Gly Met Ile Ser Ser Gln Asn Asn Asn Gly Ala Leu Asn

435 440 445Gly Leu Gly Val Gln Val Gly Tyr Lys Gln Phe Phe Gly Glu Ser Lys

450 455 460Arg Trp Gly Leu Arg Tyr Tyr Gly Phe Phe Asp Tyr Asn His Gly Tyr465 470 475 480Ile Lys Ser Ser Phe Phe Asn Ser Ser Ser Asp Ile Trp Thr Tyr Gly

485 490 495Gly Gly Ser Asp Leu Leu Val Asn Phe Ile Asn Asp Ser Ile Thr Arg

500 505 510Lys Asn Asn Lys Leu Ser Val Gly Leu Phe GlyG1y Ile Gln Leu Ala

515 S20 525Gly Thr Thr Trp Leu Asn Ser Gln Tyr Met Asn Leu Thr Ala Phe Asn

530 535 540Asn Pro Tyr Ser Ala Lys Val Asn Ala Ser Asn Phe Gln Phe Leu Phe545 550 555 560Asn Leu Gly Leu Arg Thr Asn Leu Ala Thr Ala Lys Lye Lys Asp Ser

565 570 575Glu Arg Ser Ala Gln His Gly Val Glu Leu Gly Ile Lys Ile Pro Thr

580 585 590Ile Asn Thr Asn Tyr Tyr Ser Phe Leu Gly Thr Lys Leu Glu Tyr Arg

595 600 605Arg Leu Tyr Ser Val Tyr Leu Asn Tyr Val Phe Ala Tyr

610615620 (2) SEQ ID NO 946 information

Sequence properties:

(A) length: 163 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...163

(xi) sequence representation: 946: Met Met Arg Glu Ile Leu Thr Asn Arg Phe Phe Pro Ser Leu Phe Lys 151015 Lys Arg Leu Asp Phe Ser Asn Arg Val Val Leu Gly Leu Gly Ser Asn SEQ ID NO

20 25 30Leu Lys Asn Pro Leu Lys Ile Leu Lys Ser Cys Phe Leu Tyr Phe Lys

35 40 45Asn His Ser Lys Ile Gly Lys Ile Phe Ser Ser Pro Ile Tyr Ile Asn

50 55 60Pro Pro Phe Gly Tyr Thr Asn Gln Pro Asn Phe Tyr Asn Ala Thr Ile65 70 75 80Ile Leu Lys Thr Ser Leu Gly Leu Arg His Phe Phe Ala Leu Val Phe

85 90 95Tyr Ile Glu Arg Arg Phe Gly Arg Ala Arg Lys Arg Asp Phe Lys Asp

100 105 110Ala Pro Arg Thr Leu Asp Ile Asp Ile Ile Ala Phe Asn Gln Val Ile

115 120 125Leu Arg Gln Asn Asp Leu Thr Leu Pro His Pro Lys Trp Ser Glu Arg

130135140 Asp Ser Val Leu Val Pro Leu Thr Leu Gln Gln Ile Leu Phe Lys Arg 145150155160 Glu Glu Trp (2) SEQ ID NO:947 message

Sequence properties:

(A) length: 285 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...285

(xi) sequence representation: SEQ ID NO 947 Met Gln Asp Phe Ile Lys Ile Phe Ile Gln Glu Val Val Ser Thr Leu 151015 Glu Gly Leu Val Gly Lys Ala Pro Ser Val Gly Leu Glu Lys Glu Val

2025 30Ser Asn Asn Glu Glu Ala Ser Leu Ile Ser Thr Pro Tyr Ala Arg Val

35 40 45Lys lle Ser Ala Ile Glu Lys Asn Glu Ser Pro Ile Glu Leu Leu Ala

50 55 60Pro Val Asp Leu Val Thr Ala Leu Ser Asp Leu Met Leu Gly Gly Glu65 70 75 80Gly Ala Ser Lys Glu Glu Met Asp Asn Asp Asp Leu Asp Ala Phe Lys

85 90 95Glu Met Ala Ser Asn Ile Phe Gly Ala Ile Ala Thr Ser Leu Lys Ser

100 105 110Gln Glu Leu Leu Pro Lys Leu Asn Phe Thr Thr Thr Asn Ala Glu Ile

115 120 125Ala Lys Glu Leu Pro Lys Lys Glu Asp Tyr Ala Lys Ala Met Val Phe

130 135 140Ser Phe Lys Met Glu Ala Ile Lys Glu Ser Gln Ile Val Leu Leu Ile145 150 155 160Thr Ser Ala Phe Glu Gly Gln Phe Glu Lys Thr His Lys Glu Glu Lys

165 170 175Glu Glu Thr Thr Lys Ser Ala Thr Glu Glu Thr Lys Thr His Asp Ala

180 185 190Ser Leu Glu Asn Ile Glu Ile Arg Asn Ile Ser Met Leu Leu Asp Val

195 200 205Lys Leu Asn Val Lys Val Arg Ile Gly Gln Lys Lys Met Ile Leu Lys

210 215 220Asp Val Val Ser Met Asp Ile Gly Ser Val Val Glu Leu Asp Gln Leu225 230 235 240Val Asn Asp Pro Leu Glu Ile Leu Val Asp Asp Lys Val I1e Ala Lys

245 250 255Gly Glu Val Val Ile Val Asp Gly Asn Phe Gly Ile Gln Ile Thr Asp

260 265 270Ile Gly Thr Lys Lys Glu ArG Leu Glu Gln Leu Lys Asn

275280285 (2) SEQ ID NO 948 information

Sequence properties:

(A) length: 170 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...170

(xi) sequence representation: SEQ ID NO 948 Met Lys Ile Leu Val Ile Gln Gly Pro Asn Leu Asn Met Leu Gly His 151015 Arg Asp Pro Arg Leu Tyr Gly Met Val Thr Leu Asp Gln Ile His Glu

20 25 30Ile Met Gln Thr Phe Val Lys Gln Gly Asn Leu Asp Val Glu Leu Glu

35 40 45Phe Phe Gln Thr Asn Phe Glu Gly Glu Ile Ile Asp Lys Ile Gln Glu

50 55 60Ser Val Gly Ser Asp Tyr Glu Gly Ile Ile Ile Asn Pro Gly Ala Phe65 70 75 80Ser His Thr Ser Ile Ala Ile Ala Asp Ala Ile Met Leu Ala Gly Lys

85 90 95Pro Val Ile Glu Val His Leu Thr Asn Ile Gln Ala Arg Glu Glu Phe

100 105 110Arg Lys Asn Ser Tyr Thr Gly Ala Ala Cys Gly Gly Val Ile Met Gly

115 120 125Phe Gly Pro Leu Gly Tyr Asn Met Ala Leu Met Ala Met Val Asn Ile

130 135 140Leu Ala Glu Met Lys Ala Phe Gln Glu Ala Gln Lys Asn Asn Pro Asn145 150 155 160Asn Pro Asn Asn Pro Ile Asn Asn Gln Lys

165170 (2) information SEQ ID NO:949

Sequence properties:

(A) length: 357 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...357

(xi) sequence representation: SEQ ID NO 949 Met Arg Gly Leu Glu Arg Glu Ser His Phe Thr Leu Asn Glu Asn Ala 151015 Met Phe Phe Glu Cys Ala Tyr Sar Cys Asp Asn Ala Leu Phe Leu Gln

20 25 30Leu Asp Asp Arg Ser Phe Phe Ile Thr Asp Ser Arg Tyr Thr Gln Glu

35 40 45Ala Lys Glu Ser Leu Gln Pro Lys Lys Gly Val Leu Val Glu Val Ile

50 55 60Glu Ser Ser Asp Leu Val Gln Ser Ala Ile Asp Leu Ile Thr Lys Ser65 70 75 80Ser Val Lys Lys Leu Phe Phe Asp Pro Asn Gln Val Asn Leu Gln Thr

85 90 95Tyr Lys Arg Leu Asp Ser Ala Val Gly Asn Lys Val Val Leu Glu Gly

100 105 110Val Pro Ser Tyr His Arg Gln Lys Arg Ile Ile Lys Asn Glu His Glu

115 120 125Ile Gln Leu Leu Lys Lys Ser Gln Ala Leu Asn Val Glu Ala Phe Glu

130 135 140Asn Phe Ala Glu Tyr Val Lys Lys Ile Phe Asp Glu Lys Glu Ser Leu145 150 155 160Ser Glu ArG Tyr Leu Gln His Lys Val Lys Asp Phe Leu Thr Lys Glu

165 170 175Gly Val Tyr Asp Leu Ser Phe Glu Pro Ile Leu Ala Leu Asn Ala Asn

180 185 190Ala Ser Lys Pro His Ala Leu Pro Ser Ala Lys Asp Phe Leu Lys Ala

195 200 205Asp His Ser Ile Leu Leu Asp Met Gly Ila Lys Tyr Glu Arg Tyr Cys

210 215 220Ser Asp Arg Thr Arg Thr Ala Phe Phe Asp Pro Lys Asp Phe Val Phe225 230 225 240Lys Arg Glu Gln Ser Phe Lys Asp Lys Glu Arg Gln Lys Ile Tyr Asp

245 250 255Ile Val Lys Glu Ala Gln Glu Lys Ala Ile Ser Gly Ile Arg Ala Gly

260 265 270Met Thr Gly Lys Glu Ala Asp Ser Leu Ala Arg Gly Val Ile Ser Asp

275 280 185Tyr Gly Tyr Gly Gln Tyr Phe Thr His Ser Thr Gly His Gly Ile Asp

290 295 300Leu Asp Ile His Glu Leu Pro Tyr Ile Ser Ser Arg Ser Glu Thr Ile3C5310 315 320Leu Glu Glu Gly Met Val Phe Ser Val Glu Pro Gly Ile Tyr Ile Pro

325 330 335Gly Phe Pne Gly Val Arg Ile Glu Asp Leu Val Val lle Lys Asn Ser

240 345 350Arg Ala Glu Leu Leu

355(2) SEQ ID NO:950 information

Sequence properties:

(A) length: 385 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...385

(xi) sequence representation: SEQ ID NO 950: Met Lys Asp Ser Phe Leu Phe Thr Ser Glu Ser Val Thr Glu Gly His 151015 Pro Asp Lys Met Ala Asp Gln Ile Ser Asp Ala Val Leu Asp Tyr Ile

20 25 30Ile Glu Arg Asp Lys Lys Ala Lys Val Ala Cys Glu Thr Leu Val Ser

35 40 45Asn Gly Phe Cys Met Ile Thr Gly Glu Leu Lys Thr Ser Val Tyr Ala

50 55 60Pro Met Gln Glu Ile Ala Arg Glu Val Val Lys Lys Ile Gly Tyr Thr65 70 75 80Asp Ala Leu Tyr Gly Phe Asp Tyr Arg Ser Ala Ala Val Leu Asn Gly

85 9095Ile Gly Glu Gln Ser Pro Asp Ile Asn Gln Gly Val Asp Arg Glu Asp

100 105 110Gly Glu Ile Gly Ala Gly Asp Gln Gly Leu Met Phe Gly Tyr Ala Cys

115 120 125Lys Glu Thr Glu Thr Leu Met Pro Leu Pro Ile His Leu Ala His Gln

130 135 140Leu Ala Phe Ala Leu Ala Gln Lys Arg Lys Asp Asn Thr Leu Pro Phe145 150 155 160Leu Arg Pro Asp Gly Lys Ser Gln Val Ser Val Arg Tyr Glu Asn Asn

165 170 175Lys Pro Val Ser Val Asp Thr Ile Val Ile Ser Thr Gln His Ser Pro

180 185 190Glu Val Ser Gln Lys His Leu Lys Glu Ala Val Ile Glu Glu Ile Val

195 200 205Tyr Lys Val Leu Pro Lys Glu Tyr Leu His Asp Asn Ile Lys Pne Phe

210 215 220Ile Asn Pro Thr Gly Lys Phe Val Ile Gly Gly Pro Gln Gly Asp Ala225 230 235 240Gly Leu Thr Gly Arg Lys Ile Ile Val Asp Thr Tyr Gly Gly Phe Cys

245 250 255Pro His Gly Gly Gly Ala Phe Ser Gly Lys Asp Pro Ser Lys Val Asp

260 265 270Arg Ser Ala Ala Tyr Ala Ala Arg Tyr Val Ala Lys Asn Leu Val Ala

275 280 285Ser Gly Val Cys Asp Lys Ala Thr Val Gln Leu Ala Tyr Ala Ile Gly

290 295 300Val Ile Glu Pro Val Ser Ile Tyr Val Asn Thr His Asn Thr Ser Lys305 310 315 320His Ser Ser Ala Glu Leu Glu Lys Cys Val Lys Ser Val Phe Lys Leu

325 330 335Thr Pro Lys Gly Ile Ile Glu Ser Leu Asp Leu Leu Arg Pro Ile Tyr

340 345 350Ser Leu Thr Ser Ala Tyr Gly His Phe G1y Arg Glu Leu Glu Glu Phe

355 360 365Thr Trp Glu Lys Thr Asn Lys Val Glu Glu Ile Lys Ala Phe Phe Lys

370375380 Arg385(2) SEQ ID NO:951 information

Sequence properties:

(A) length: 218 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...218

(xi) sequence representation: SEQ ID NO 951: Val Leu Asp Ser Phe Glu Ile Leu Lys Ala Leu Lys Ser Leu Asp Leu 151015 Leu Lys Asn Ala Pro Ala Trp Trp Trp Pro Asn Ala Leu Lys Phe Glu

20 25 30Ala Leu Leu Gly Ala Val Leu Thr Gln Asn Thr Lys Phe Glu Ala Val

35 40 45Leu Lys Ser Leu Glu Asn Leu Lys Asn Ala Phe Ile Leu Glu Asn Asp

50 55 60Asp Glu Ile Ash Leu Lys Lys Ile Ala Tyr Ile Glu Phe Ser Lys Leu65 70 75 80Ala Glu Cys Val Arg Pro Ser Gly Phe Tyr Asn Gln Lys Ala Lys Arg

85 90 95Leu Ile Asp Leu Ser Lys Asn Ile Leu Lys Asp Phe Gln Ser Phe Glu

100 105 110Asn Phe Lys Gln Glu Val Thr Lys Glu Trp Leu Leu Asp Gln Lys Gly

115 120 125Ile Gly Lys Glu Ser Ala Asp Ala Ile Leu Cys Tyr Val Cys Ala Lys

130 135 140Glu Val Met Val Val Asp Lys Tyr Ser Tyr Leu Phe Leu Lys Lys Leu145 150 155 160Gly Ile Glu Ile Glu Asp Tyr Asp Glu Leu Gln His Phe Phe Glu Lys

165 170 175Gly Val Gln Glu Asn Leu Asn Ser Ala Leu Ala Leu Tyr Glu Asn Thr

180 185 190Ile Ser Leu Ala Gln Leu Tyr Ala Arg Pne His Gly Lys Ile Val Glu

195 200 205Phe Ser Lys Gln Lys Leu Glu Leu Lys Leu

210215 (2) SEQ ID NO 952 information

Sequence properties:

(A) length: 132 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...132

(xi) sequence representation: SEQ ID NO 952: Met Lys Gln Leu Phe Leu Ile Ile Gly Ala Pro Gly Ser Gly Lys Thr 151015 Thr Asp Ala Glu Leu Ile Ala Lys Asn Asn Ser Glu Thr Ile Ala His

20 25 30Phe Ser Thr Gly Asp Leu Leu Arg Ala Glu Ser Ala Lys Lys Thr Glu

35 40 45Arg Gly Leu Leu I1e Glu Lyg Phe Thr Ser Gln Gly Glu Leu Val Pro

50 55 60Leu Glu Ile Val Val Glu Thr Ile Leu Ser Ala Ile Lys Ser Ser Ser65 70 75 80Lys Gly Ile Ile Leu Ile Asp Gly Tyr Pro Arg Ser Val Glu Gln Met

85 90 95Gln Ala Leu Asp Lys Glu Leu Asn Ala Pro Asn Glu Val Ile Leu Lys

100 105 110Ser Val Ile Glu Val Glu Val Ser Glu Asn Thr Ala Lys Glu Arg Val

115 120 125Leu Gly Gln Phe

130(2) SEQ ID NO 953 message

Sequence properties:

(A) length: 153 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...153

(xi) sequence representation: SEQ ID NO 953: Met His Tyr Ser Tyr Glu Ala Phe Leu Lys Asp Ser Leu Glu Leu Ala 151015 Lys Gln Val Glu Arg Leu Cys Gly Ile Pro Glu Ala Leu Val Cys Val

20 25 30Met Arg Gly Gly Met Thr Leu Val His Phe Leu Ser Leu His Trp Asn

35 40 45Leu Arg Glu Val Tyr Gly Ile Asn Ala Ile Ser Tyr Asp Thr Thr Lys

50 55 60Arg Gln ASn Ala Leu Lys Ile Glu Asn Thr Pro Thr Ile Lys Asp His65 70 75 80Leu Lys Thr Ile Leu Val Val Asp Glu Ile Val Asp Ser Gly Asn Ser

85 90 95Leu Glu Ala Val Leu Lys Val Leu Gln Asp Lys His Pro Asp Lys Lys

100 105 110Phe Tyr Ser Ala Ser Leu Phe Gln Lys Thr Ser Ala Lys Tyr Lys Ala

115 120 125Asp Ala Phe Leu Lys Asp Ala Pro Glu Trp Ile Asp Phe Phe Trp Glu

130135140 Val Asp Leu Lys Asn Leu Lys Ser His 145150 (2) SEQ ID NO:954 information

Sequence properties:

(A) length: 235 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...235

(xi) sequence representation: 954: Leu Ser Glu Pro Ile Asp Arg Phe Thr Arg Ile Arg Trp Leu Phe Lys 151015 Asn Asp Phe Glu Lys Ile Arg Gln Gln Arg Val Leu Ile Cys Gly Val SEQ ID NO

20 25 30Gly Gly Val Gly Gly Phe Ala Leu Asp Ser Leu Tyr Arg Val G1y Ile

35 40 45Gly Gln Ile Thr Ile Ile Asp Lys Asp Met Phe Asp Val Thr Asn Gln

50 55 60Asn Arg Gln Ile Gly Ser Glu Arg Ile Gly Glu Ser Lys Val Leu Val65 70 75 80Leu Gln Asp Leu Tyr Lys Gly Ile Gln Ala Leu Asn Cys Arg Ile Asp

85 90 95Glu Ala Phe Leu Asn Ser Phe Asn Phe Arg Asp Tyr Asp Tyr Ile Leu

100 105 110Asp Cys Met Asp Asp Leu Pro Ile Lys Thr Ser Leu Ala Ile Lys Cys

115 120 125Gln Asn Phe Ala Tyr Gly Lys Phe Ile Ser Ser Met Gly Ser Ala Lys

130 135 140Arg Leu Asn Pro Lys His Ile Gln VaL Gly Ser Val Trp Glu Ser Tyr145 150 155 160Gly Asp Lys Phe Gly Arg Lys Phe Arg Asp Phe Leu Lys Lys Arg Arg

165 170 175Phe Lys Gly Asp Phe Lys Val Val Phe Ser Pro Glu Val Pro His Cys

180 185 190Ile Glu Leu Gly Ser Phe Asn Ala Val Thr Ala Ser Phe Gly Leu Gln

195 200 205Ile Ala Ser Glu Val Val Gln Asp Ile Ile Lys Asn Glu Arg Gln Trp

2102 l 5220 Asn Glu Arg Leu Arg Arg Arg Ile Gly Arg Phe 225230235 (2) SEQ ID NO:955 information

Sequence properties:

(A) length: 439 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...439

(xi) sequence representation: SEQ ID NO 955: Met Gln Val Lys Glu Asn Lys Gln Leu Cys Leu Ile Ser Leu Gly Cys 151015 Ser Lys Asn Leu Val Asp Ser Glu Val Met Leu Gly Lys Leu Tyr Asn 202530 Tyr Thr Leu Thr Asn Asp Ala Lys Lys Ala Asp Val Ile Leu Ile Asn

35 40 45Thr Cys Gly Phe Ile Glu Ser Ala Lys Gln Glu Ser Ile Gln Thr Ile

50 55 60Leu Asn Ala Ala Lys Asp Lys Lys Glu Gly Ala Ile Leu Ile Ala Ser65 70 75 80Gly Cys Leu Ser Glu Arg Tyr Lys Asp Glu Ile Lys Glu Leu Ile Pro

85 90 95Glu Val Asp Ile Phe Thr Gly Val G1y Asp Tyr Asp Lys Ile Asp Ile

100 105 110Leu Ile Ala Lys Lys Gln Asn Gln Phe Ser Glu Gln Val Phe Leu Ser

115 120 125Glu His Tyr Asn Ala Arg Ile Ile Thr Gly Ser Ser Val His Ala Tyr

130 135 140Val Lys Ile Ser Glu Gly Cys Asn Gln Lys Cys Ser Phe Cys Ala Ile145150 155 160Pro Ser Phe Lys Gly Lys Leu Gln Ser Arg Glu Leu Asp Ser Ile Leu

165 170 175Lys Glu Val Glu Asp Leu Ala Leu Lys Gly Tyr Lys Asp Met Thr Phe

180 185 190Ile Ala Gln Asp Ser Ser Ser Phe Leu Tyr Asp Lys Gly Gln Lys Asp

195 200 205Gly Leu Ile Gln Leu Ile Arg Ala Ile Asp Lys Gln Gln Ala Leu Lys

210 215 220Ser Ala Arg Ile Leu Tyr Leu Tyr Pro Ser Ser Thr Thr Leu Glu Leu225 230 235 240Ile Gly Ala Ile Glu Asp Ser Pro Ile Phe Gln Asn Tyr Phe Asp Met

245 250 255Pro Ile Gln His Ile Ser Asp Ser Met Leu Lys Lys Met Arg Arg Asn

260 265 270Ser Ser Gln Ala His His Leu Lys Leu Leu Asn Ala Met Lys Gln Val

275 280 285Lys Glu ser Phe Ile Arg Ser Thr Ile Ile Val Gly His Pro Glu Glu

290 295 300Asn Glu Ser Glu Phe Glu Glu Leu Ser Ala Phe Leu Asp Glu Phe Arg 305 310 315 320Phe Asp Arg Leu Asn Ile Phe Ala Phe Ser Ala Glu Glu Asn Thr His

325 330 335Ala Tyr Ser Leu Glu Lys Val Pro Lys Lys Ile Ile Asn Ala Arg Ile

340 345 350Lys Ala Leu Asn Lys Ile Ala Leu Lys His Gln Asn His Ser Phe Lys

355 360 365Ala Leu Leu Asn Lys Pro Ile Lys Ala Leu Val Glu His Lys GluGly

370 375 380Glu Tyr Phe Tyr Lys Ala Arg Asp Leu Arg Trp Ala Pro Glu Val Asp385 390 395 400Gly Glu Ile Leu Ile Asn Asp Ser Glu Leu Thr Thr Pro Leu Lys Pro

405 410 415Gly His Tyr Thr Ile Val Pro Ser Ala Phe Lys Asp Asn Ile Leu Leu

420 425 430Ala Lys Val Leu Ser Pro Phe

435(2) SEQ ID NO 956 information

Sequence properties:

(A) length: 667 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...667

(xi) sequence representation: SEQ ID NO:956: Lys Lys Pro Phe Tyr Ser Leu Ser Leu Ala Ser Ser Leu Leu Asn Ala 151015 Glu Asp Asn Gly Phe Phe Ile Ser Ala Gly Tyr Gln Ile Gly Glu Ala

20 25 30Ala Gln Met Val Lys Asn Thr Gly Glu Leu Lys Lys Leu Ser Asp Thr

35 40 45Tyr Glu Asn Leu Ser Asn Leu Leu Thr Asn Phe Asn Asn Leu Asn Gln

50 55 60Ala Val Thr Asn Ala Ser Ser Pro Ser Glu Ile Asn Ala Ala Ile Asp65 7075 80Asn Leu Lys Ala Asn Thr Gln Gly Leu Ile Gly Glu Lys Thr Asn Ser

85 90 95Pro Ala Tyr Gln Ala Val Tyr Leu Ala Leu Asn Ala Ala Val Gly Leu

100 105 110Trp Asn Val Ile Ala Tyr Asn Val Gln Cys Gly Pro Gly Asn Ser Gly

115 120 125Gln Gln Ser Val Thr Phe Glu Gly Gln Pro Gly His Asn Ser Ser Ser

130 135 140Ile Asn Cys Asn Leu Thr Gly Tyr Asn Asn Gly Val Ser Gly Pro Leu145 150 155 160Ser Ile Glu Asn Phe Lys Lys Leu Asn Gln Ala Tyr Gln Thr Ile Gln

165 170 175Gln Ala Leu Lys Gln Asp Ser Gly Phe Pro Val Leu Asp Ser Ala Gly

180 185 190Lys Gln Val Thr Ile Thr Ile Thr Thr Gln Thr Asn Gly Ala Asn Lys

195 200 205Ser Glu Thr Thr Thr Thr Thr Thr Thr Thr Asn Asp Ala Gln Thr Leu

210 215 220Leu Gln Glu Ala Ser Lys Met Ile Ser Val Leu Thr Thr Asn Cys Pro225 230 235 240Trp Val Asn His Asn Gln Gly Gln Asn Gly Gly Ala Pro Trp Gly Leu

245 250 255Asp Thr Ala Gly Asn Val Cys Gln Val Phe Ala Thr Glu Phe Ser Ala

260 265 270Val Thr Ser Met Ile Lys Asn Ala Gln Glu Ile Val Thr Gln Ala Gln

275 280 285Ser Leu Asn Gln Gln Asn Asn Gln Asn Ala Pro Gln Asp Phe Asn Pro

290295 300Tyr Thr Ser Ala Asp Arg Ala Phe Ala Gln Asn Met Leu Asn His Ala305 310 315 320Gln Ala Gln Ala Lys Ile Leu Glu Leu Ala Asp Gln Met Lys Lys Asp

325 330 335Leu Asn Thr Ile Pro Ser Gln Phe Ile Thr Asn Tyr Leu Ala Ala Cys

340 345 350His Asn Gly Gly Gly Thr Leu Pro Asp Ala Gly Val Thr Asn Asn Thr

355 360 365Trp Gly Ala Gly Cys Ala Tyr Val Giu Glu Thr Ile Thr Ala Leu Asn

370 375 380Asn Ser Leu Ala His Phe Gly Thr Gln Ala Glu Gln Ile Lys Gln Ser385 390 395 400Glu Leu Leu Ala Arg Thr Ile Leu Asp Phe Arg Gly Ser Leu Ser Asn

405 410 415Leu Asn Asn Thr Tyr Asn Ser Ile Thr Thr Thr Ala Ser Asn Thr Pro

420 425 430Asn Ser Pro Phe Leu Lys Asn Leu Ile Ser Gln Ser Thr Asn Pro Asn

435 440 445Asn Pro Gly Gly Leu Gln Ala Val Tyr Gln Val Asn Gln Ser Ala Tyr

450 455 460Ser Gln Leu Leu Ser Ala Thr Gln Glu Leu Gly His Asn Pro Phe Arg465 470 475 480Arg Val Gly Leu Ile Ser Ser Gln Thr Asn Asn Gly Ala Met Asn Gly

485 490 495Ile Gly Val Gln Val Gly Tyr Lys Gln Phe Phe Gly Glu Lys Arg Arg

500 505 510Trp Gly Leu Arg Tyr Tyr Gly Phe Phe Asp Tyr Asn His Ala Tyr Ile

515520 525Lys Ser Ser Phe Phe Asn Ser Ala Ser Asp Val Phe Thr Tyr Gly Val

530 535 540Gly Thr Asp Val Leu Tyr Asn Phe Ile Asn Asp Lys Thr Thr Lys Asn545 550 555 560Ser Lys Ile Ser Phe Gly Val Phe Gly Gly Ile Ala Leu Ala Gly Thr

565 570 575Ser Trp Leu Asn Ser Gln Tyr Val Asn Leu Ala Thr Phe Asn Asn Phe

580 585 590Tyr Ser Ala Lys Met Asn Val Ala Asn Phe Gln Phe Leu Phe Asn Leu

595 600 605Gly Leu Arg Met Asn Leu Ala Lys Asn Lys Lys Lys Ala Ser Asp His

610 615 620Ala Ala Gln His Gly Val Glu Leu Gly Val Lys Ile Pro Thr Ile Asn625 630 635 640Thr Asn Tyr Tyr Ser Leu Leu Gly Thr Gln Leu Gln Tyr Arg Arg Leu

645 650 655Tyr Ser Val Tyr Leu Asn Tyr Val Phe Ala Tyr

660665 (2) information of SEQ ID NO:957

Sequence properties:

(A) length: 87 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...87

(xi) sequence representation: SEQ ID NO 957: Met Phe Ile Leu Phe Lys Phe Gly Arg Val Leu Gly Lys Ala Tyr Ser 151015 Leu Tyr Leu Tyr Ile Tyr Glu Ser Leu lle Cys Gln Ala Phe Gly Leu

20 25 30Ser Leu Ser Cys Asn Asn Ser Met Leu Phe Ser Thr Phe Leu Ile Asn

35 40 45Leu Pro Leu Pro His Asn Glu Ser Leu Cys Cys Cys Arg Asp Ile Leu

50 55 60Ala Tyr Ser Asn Ser Ser Ser Leu Lys Thr Tyr Ser Leu Glu Ser Asn65 70 75 80Phe Ser Phe Asn Ser Leu Phe

85(2) SEQ ID NO 958 message

Sequence properties:

(A) length: 134 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...134

(xi) sequence representation: SEQ ID NO:958: Met Phe Met Ala Ser Ile Arg Thr Leu Thr His Met Thr Asn Ala Asp 151015 Gly Thr Ile Thr Cys Gly Asp Thr Thr Pro Ala Ser Cys Asn Val Gly

20 25 30Ile Asn Pro Asn Ser Val Tyr Thr Thr Gly Lys Leu Asn Ala Lys Val

35 40 45Asn His Thr Ile Phe Gln Phe Leu Val Asn Val Gly Ile ArgThr Asn

50 55 60Ile Phe Glu His His Gly Ile Glu Phe Gly Ile Lys Ile Pro Thr Leu65 70 75 80Pro Asn Tyr Phe Phe Lys Gly Ser Thr Thr Ile Arg Ala Lys Lys Gln

85 90 95Gly Pro Leu Glu Asn Gly Asn Pro Thr Thr Ile Thr Gly Ala Glu Thr

100 105 110Asn Phe Ser Leu Thr Gln Thr Leu Arg Arg Gln Tyr Ser Met Tyr Leu

115 120 125Arg Tyr Val Tyr Thr Phe

130(2) SEQ ID NO 959 message

Sequence properties:

(A) length: 278 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...278

(xi) sequence representation: SEQ ID NO 959: Leu Asn Lys Leu Leu Lys Lys Gly Phe Leu Ala Phe Phe Leu Ser Val 151015 Tyr Leu Arg Ala Asp Asp Leu Val Thr Tyr Thr Ile Ala Lys Glu Glu

20 25 30Asp Leu Gly Tyr Gln Arg Phe Leu Ala Lys Lys Cys Leu Arg Gly Lys

35 40 45Thr His Pro Pro Cys Phe Thr Ala Ser Lys Lys Pro Lys Arg Lys Pro

50 5560Phe Asn Ile Asp Lys Ser Ser His Tyr Tyr Gly Thr Ser Val Val Gln65 70 75 80Met Ser Trp Leu Gln Ser Arg Glu Lys Phe Glu Asn His Ser Lys Tyr

85 90 95Arg Asn Ile Pro Phe Ala Glu Val Ser Leu Ile Tyr Gly Tyr Lys Gln

100 105 110Phe Phe Pro Lys Lys Glu His Tyr Gly Phe Arg Phe Tyr Val Ser Leu

115 120 125Asp Tyr Ala Tyr Gly Phe Phe Leu Lys Asn Lys Gly Ala Leu Gly Asp

130 135 140Ser Leu Arg Ala Ser Ser Gln Ile Pro Lys Ser Tyr Arg Glu Lys Leu145 150 155 160Gln Arg Lys Glu Thr Phe Ile Asn Ala Ile Phe Tyr Gly Val Gly Ala

165 170 175Asp Phe Leu Tyr Lys Arg Ala Phe Gly Thr Leu Ile Leu Gly Val Asn

180 185 190Phe Val Gly Glu Thr Trp Phe Tyr Glu Thr Lys Ile Phe Lys Gln Trp

195 200 205Ala Lys Asp Ser Leu Asn Thr Tyr Arg Pro Asn Met Phe Gln Val Met

210 215 220Leu Asn Val Gly Tyr Arg Tyr Arg Phe Ser Arg Tyr Lys Asn Trp Ala225 230 235 240Ile Glu Phe Gly Ala Arg Ile Pro Phe Leu Ile Asn Asp Tyr Phe Lys

245 250 255Thr Pro Leu Tyr Thr Leu His Phe Lys Arg Asn Ile Ser Val Tyr Leu

260 265 270Thr Ser Thr Tyr Asp Phe

275(2) SEQ ID NO:960 information

Sequence properties:

(A) length: 499 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...499

(xi) sequence representation: SEQ ID NO 960: Met Lys Leu Lys Lys ArG Lys Val Ala Ala Thr Leu Leu Lys Arg Leu 151015 Thr Leu Pro Leu Leu Phe Thr Thr Gly Ser Leu Gly Ala Val Thr Tyr

20 25 30Glu Val His Gly Asp Phe Ile Asn Phe Ser Lys Val Gly Phe Asn Arg

35 40 45Ser Pro Ile Asn Pro Val Lys Gly Ile Tyr Pro Thr Glu Thr Phe Val

50 55 60Asn Leu Thr Gly Lys Leu Glu Gly Ser Val His Leu Gly Arg Gly Trp65 70 75 80Thr Val Asn Val Gly Gly Val Leu Gly Gly Gln Val Tyr Asp Asn Thr

85 90 95Arg Tyr Asp Arg Trp Ala Lys Asp Phe Thr Pro Pro Ser Tyr Trp Asp

100 105 110Lys Thr Ser Cys Gly Thr Asp Ser Leu Ser Leu Cys Met Asn Ala Thr

115 120 125Lys Met Trp Gln Gln Gln Gly Pro Gly Gly Ile Ile Asp Pro Arg Gly130 135 140Ile Gly Tyr Met Tyr Met Gly Glu Trp Asn Gly Leu Phe Pro Asn Tyr145 150 155 160Tyr Pro Ala Asn Ala Tyr Leu Pro Gly His Ser Arg Arg Tyr Glu Val

165 170 175Tyr Lys Ala Asn Leu Thr Tyr Asp Ser Asp Arg Val His Met Val Met

180 185 190Gly Arg Phe Asp Val Thr Glu Gln Glu Gln Met Asp Trp Ile Tyr Gln

195 200 205Leu Phe Gln Gly Phe Tyr Gly Thr Phe Lys Leu Thr Lys Asn Met Lys

210 215 220Phe Leu Leu Phe Ser Ser Trp Gly Arg Gly Ile Ala Asp Gly Gln Trp225 230 235 240Leu Phe Pro Ile Tyr Arg Glu Lys Pro Trp Gly Ile His Lys Ala Gly

245 250 255Ile Ile Tyr Arg Pro Thr Lys Asn Leu Met Ile His Pro Tyr Val Tyr

260 265 270Leu Ile Pro Met Val Gly Thr Leu Pro Gly Ala Lys Ile Glu Tyr Asp

275 280 285Thr Asn Pro Glu Phe Ser Gly Arg Gly lle Arg Asn Lys Thr Thr Phe

290 295 300Tyr Val Leu Tyr Asp Tyr Arg Trp Asn Asn Ala Glu Tyr Gly Arg Tyr305 310 315 320Ala Pro Ala Arg Tyr Asn Thr Trp Asp Pro Phe Leu Asp Asn Gly Lys

325 330 335Trp Arg Gly Leu Gln Gly Pro Gly Gly Ala Thr Leu Tyr Leu His His

340 345 350His Ile Asp Ile Asn Asn Tyr Phe Val Val Gly Gly Ala Tyr Leu Asn

355 360 365Ile Gly Asn Pro Asn Met Asn Leu Gly Thr Trp Gly Asn Pro Val Ala

370 375 380Leu Asp Gly Ile Glu Gln Trp Val Gly Gly Ile Tyr Ser Leu Gly Phe385 390 395 400Ala Gly Ile Asp Asn Ile Thr Asp Ala Asp Ala Phe Thr Glu Tyr Val

405 410 415Lys Gly Gly Gly Lys His Gly Lys Phe Ser Trp Ser Val Tyr Gln Arg

420 425 430Phe Thr Thr Ala Pro Arg Ala Leu Glu Tyr Gly Ile Gly Met Tyr Leu

435 440 445Asp Tyr Gln Phe Ser Lys His Val Lys Ala Gly Leu Lys Leu Val Trp

450 455 460Leu Glu Phe Gln Ile Arg Ala Gly Tyr Asn Pro Gly Thr Gly Phe Leu465 470 475 480Gly Pro Asn Gly Gln Pro Leu Asn Leu Asn Asn Gly Leu Phe Glu Ser

485490495 Ser Ala Phe (2) SEQ ID NO:961 information

Sequence properties:

(A) length: 68 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...68

(xi) sequence representation: SEQ ID NO 961: Leu Lys Glu Lys Phe Asp Phe Phe Lys Gly Lys Asn Phe Lys Ile Val 151015 Tyr Cys Ile Gly Glu Asp Leu Thr Thr Arg Glu Lys Gly Phe Arg Ala

20 25 30Val Lys Glu Phe Leu Ser Glu Gln Leu Glu Asn Ile Asp Leu Asn Tyr

35 40 45Ser Asn Leu Ile Val Ala Tyr Glu Pro Ile Trp Ala Ile Gly Thr Lys

505560 Lys Ala Arg Phe65(2) SEQ ID NO:962 information

Sequence properties:

(A) length: 263 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...263

(xi) sequence representation: 962: Met Ser Lys Ser Ala Ile Phe Val Leu Ser Gly Phe Leu Ala Phe Leu 151015 Leu Tyr Ala Leu Leu Leu Tyr Gly Leu Leu Leu Glu Arg His Asn Lys SEQ ID NO

20 25 30Glu Ala Glu Lys Ile Leu Leu Asp Leu Asn Lys Lys Asp Glu Gln Ala

35 40 45Ile Asp Leu Asn Leu Glu Asp Leu Pro Ser Glu Lys Lys Asn Glu Lys

50 55 60Ile Glu Lys Val Thr Glu Lys Gln Gly Asp Phe Leu Glu Pro Lys Glu65 70 75 80Glu Pro Lys Glu Glu Pro Glu Glu Ser Leu Glu Asp Ile Phe Ser Ser

85 90 95Leu Asn Asp Phe Gln Glu Lys Thr Asp Lys Asn Ala Gln Lys Asp Glu

100 105 110Gln Lys Asn Glu Gln Glu Glu Gln Arg Arg Leu Arg Glu Gln Gln Arg

115 120 125Leu Lys Gln Asn Gln Glu Asn Gln Glu Me5 Leu Lys Gly Leu Gln Gln

130 135 140Asn Leu Asn Gln Phe Thr Gln Lys Leu Glu Ser Val Lys Asn Lys Thr145 150 155 160Leu Asp Leu Gln Ile Pro Lys Gln Asp Gly Val Asp Glu Lys Ala Tyr

165 170 175Gln Glu Trp Tyr Ala Gln Ile Tyr Gln Ile Leu Tyr Lys Gly Trp Arg

180 185 190Gly Val Phe Tyr His Lys Ala Ser Val Ser Val Leu Ile Met Ile Thr

195 200 205Lys Asp Gly Glu Phe Asp Tyr Thr Ile Leu Ser Tyr Ser Asp Phe Lys

210 215 220Asp Tyr Asn Lys Ser Val Met Thr Leu Leu Asp Asp Leu Lys Lys Val225 230 235 240Asp Phe Pro Pro Tyr Pro Gly Gly Asn Met Ile Ser Ile Lys Val Asn

245 250 255Phe Thr Thr Lys Glu Glu Gln

260(2) SEQ ID NO 963 information

Sequence properties:

(A) length: 785 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...785

(xi) sequence representation: SEQ ID NO 963 Met Glu Gln Pro Val Ile Lys Glu Gly Thr Leu Ala Leu Ile Asp Thr 151015 Phe Ala Tyr Leu Phe Arg Ser Tyr Tyr Met Ser Ala Lys Asn Lys Pro

20 25 30Leu Thr Asn Asp Lys Gly Phe Pro Thr GLy Leu Leu Thr Gly Leu Val

35 40 45Gly Met Val Lys Lys Phe Tyr Lys Asp Arg Lys Asn Met Pro Phe Ile

50 55 60Val Phe Ala Leu Glu Ser Gln Thr Lys Thr Lys Arg Ala Glu Lys Leu65 70 75 80Gly Glu Tyr Lys Gln Asn Arg Lys Asp Ala Pro Lys Glu Met Leu Leu

85 90 95Gln Ile Pro Ile Ala Leu Glu Trp Leu Gln Lys Met G1y Phe Thr Cys

100 105 110Val Glu Val Gly Gly Phe Glu Ala Asp Asp Val Ile Ala Ser Leu Ala

115 120 125Thr Leu Ser Pro Tyr Lys Thr Arg Ile Tyr Ser Lys Asp Lys Asp Phe

130 135 140 Asn Gln Leu Leu Ser Asp Lys Ile Ala Leu Phe Asp Gly Lys Thr Glu145 150 155 160Phe Leu Ala Lys Asp Cys Val Glu Lys Tyr Gly Ile Leu Pro Ser Gln

165 170 175Phe Thr Asp Tyr Gln Gly Ile Val Gly Asp Ser Ser Asp Asn Tyr Lys

180 185 190Gly Val Lys Gly Ile Gly Ser Lys Asn Ala Lys Glu Leu Leu Gln Arg

195 200 205Leu Gly Ser Leu Glu Lys Ile Tyr Glu Asn Leu Asp Leu Ala Lys Asn

210 215 220Leu Leu Ser Pro Lys Met Tyr Gln Ala Leu Ile Gln Asp Lys Gly Ser225 230 235 240Ala Phe Leu Ser Lys Glu Leu Ala Thr Leu Glu Arg Gly Cys Ile Lys

245 250 255Glu Phe Asp Phe Leu Ser Cys Ala Phe Pro Ser Glu Asn Pro Leu Leu

260 265 270Lys Ile Lys Asp Glu Leu Lys Glu Tyr Gly Phe Ile Ser Thr Leu Arg

275 280 285Asp Leu Glu Asn Ser Pro Phe Ile Val Glu Asn Val Pro Ile Leu Asn

290 295 300Ser Thr Pro Ile Leu Asp Asn Thr Pro Ala Leu Asp Asn Ala Pro Lys305 310 315 320Lys Ser Arg Met Ile Val Leu Glu Ser Ala Glu Pro Leu Ser Met Phe

325 330 335Leu Glu Lys Leu Glu Asn Pro Asn Ala Arg Val Phe Met Arg Leu Val

340 345 350Leu Asp Lys Asp Lys Lys Ile Leu Ala Leu Ala Phe Leu Leu Gln Asp

355 360 365Gln Gly Tyr Phe Leu Pro Leu Glu Glu Ala Leu Phe Ser Pro Phe Ser

370 375 380Leu Glu Phe Leu Gln Asn Ala Phe Ser Gln Met Leu Gln His Ala Cys385 390 395 400Ile Ile Gly His Asp Leu Lys Pro Leu Leu Ser Phe Leu Lys Ala Lys

405 410 415Tyr Gln Val Pro Leu Glu Asn Ile Arg Ile Gln Asp Thr Gln Ile Leu

420 425430Ala Phe Leu Lys Asn Pro Glu Lys Val Gly Phe Asp Glu Val Leu Lys

435 440 445Glu Tyr Leu Lys Glu Asp Leu Ile Pro His Glu Lys Ile Lys Asp Phe

450 455 460Lys Thr Lys Ser Lys Ala Glu Lys Ser Glu Leu Leu Ser Met Glu Leu465 470 475 480Asn Ala Leu Lys Arg Leu Cys Glu Tyr Phe Glu Lys Gly Gly Leu Glu

485 490 495Glu Asp Leu Leu Thr Leu Ala Arg Asp Ile Glu Thr Pro Phe Val Lys

500 505 510Val Leu Met Gly Met Glu Phe Gln Gly Phe Lys Ile Asp Ala Pro Tyr

515 S20 525Phe Lys Arg Leu Glu Gln Glu Phe Lys Asn Glu Leu Asn Val Leu Glu

530 535 540Arg Gln Ile Leu Asp Leu Ile Gly Val Asp Phe Asn Leu Asn Ser Pro545 550 555 560Lys Gln Leu Gly Glu Val Leu Tyr Asp Lys Leu Gly Leu Pro Lys Asn

565 570 575Lys Ser His Ser Thr Asp Glu Lys Asn Leu Leu Lys Ile Leu Asp Lys

580 585 590His Pro Ser Ile Pro Leu Ile Leu Glu Tyr Arg Glu Leu Asn Lys Leu

595 600 605Phe Asn Thr Tyr Thr Thr Pro Leu Leu Arg Leu Lys Asp Lys Asp Asp

610 615 620Lys Ile His Thr Thr Phe Ile Gln Thr Gly Thr Ala Thr Gly Arg Leu625 630 635 640Ser Ser His Ser Pro Asn Leu Gln Asn Ile Pro Val Arg Ser Pro Lys

645 650655Gly Leu Leu Ile Arg Lys Gly Phe Ile Ala Ser Ser Lys Glu Tyr Cys

660 665 670Leu Leu Gly Val Asp Tyr Ser Gln Ile Glu Leu Arg Leu Leu Ala His

675 680 685Phe Ser Gln Asp Lys Asp Leu Met Glu Ala Phe Leu Lys Gly Arg Asp

690 695 700Ile His Leu Glu Thr Ser Lys Ala Leu Phe Gly Glu Asp Leu Ala Lys705 710 715 720Glu Lys Arg Ser Ile Ala Lys Ser Ile Asn Phe Gly Leu Val Tyr Gly

725 730 735Met Gly Ser Lys Lys Leu Ser Glu Thr Leu Ser Ile Pro Leu Ser Glu

740 745 750Ala Lys Ser Tyr Ile Glu Ala Tyr Phe Lys Arg Phe Pro Ser Ile Lys

755 760 765Asp Tyr Leu Asn Gly Met Arg Glu Glu Ile Leu Lys Thr Ser Lys Ala

770775780 Phe785(2) SEQ ID NO:964 information

Sequence properties:

(A) length: 55 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...55

(xi) sequence representation: SEQ ID NO 964: Val Ser Glu Ser Glu Lys Gln Glu Ile Glu Asn Lys Ile Glu Glu Arg 151015 Lys Arg Ala Lys Glu Gln Lys Asp Phe Leu Lys Ala Asp Ser Ile Arg

20 25 30Glu Glu Leu Leu Gln Gln Lys Ile Ala Leu Met Asp Thr Pro Gln Gly

35 40 45Thr Ile Trp Glu Lys Leu Phe

5055 (2) SEQ ID NO 965 message

Sequence properties:

(A) length: 571 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...571

(xi) sequence representation: SEQ ID NO:965: Leu Pro Ser Val Gln Ile Trp Gly Ser Tyr Thr Asn Ser Phe Lys Gln 151015 Thr Phe Ser Ala Ser Asn Ser Asn Leu Val Ile Gly Tyr Asn Ala Thr

20 25 30Trp Thr Asp Pro Asn Val Ser Ser Ser Asp Thr Val Ala Phe Gly Asp

35 40 45Pro Ser Gly Ser Ala Leu Asn Gly His Cys Gly Pro Trp Pro Tyr Tyr

50 55 60Gln Cys Thr G1y Thr Thr Asn Gly Thr Tyr Ser Ala Tyr His Val Tyr65 70 75 80Ile Thr Ala Asn Leu Arg Ser Gly Asn Arg Ile Gly Thr Gly Gly Ala

85 90 95Ala Asn Leu Ile PheAsn Gly Val Asp Ser Ile Asn Ile Ala Asn Ala

100 105 110Thr Ile Thr Gln His Asn Ala Gly Ala Tyr Ser Ser Ser Met Thr Phe

115 120 125Ser Thr Gln Asn Met Asp Asn Ser Gln Asn Leu Asn Gly Leu Asn Ser

130 135 140Asn Gly Lys Leu Leu Val Tyr Gly Thr Thr Phe Thr Asn Gln Ala Lys145 150 155 160Asp Gly Lys Phe Ile Phe Asn Ala Gly Gln Ala Thr Phe Glu Asn Thr

165 170 175Asn Phe Asn Gly Gly Ser Tyr Gln Phe Ser Gly Asp Ser Leu Asn Phe

180 185 190Ser Asn Asn Asn Gln Phe Asn Ser Gly Ser Phe Glu Ile Gly Ala Lys

195 200 205Asn Thr Ile Phe Asn Asn Ala Asn Phe Asn Asn Ser Thr Ser Phe Asn

210 215 220Phe Asn Asn Ser Ser Ala Thr Thr Ser Phe Val Gly Asp Phe Thr Asn225 230 235 240Ala Asn Ser Asn Leu Gln Ile Ala Gly Asn Ala Val Phe Gly Asn Ser

245 250 255Thr Asn Gly Ser Gln Asn Thr Ala Asn Phe Asn Asn Thr Gly Ser Val

260 265 270Asn Ile Ala Gly Asn Ala Thr Phe Asp Asn Val Val Phe Asn Ser Pro

275 280 285Thr Asn Thr Ser Val Lys Gly Lys Val Thr Leu Asn Asn Ile Thr Leu

290 295 300Lys Asn Leu Asn Ala Pro Leu Ser Phe Gly Asp Gly Thr Ile Val Phe305 310 315 320Ser Ala His Ser Val Ile Asn Ile Gly Glu Ala Ile Thr Asn Gly Asn

325 330 335Pro Ile Thr Leu Val Ser Ser Ser Lys Ala Ile Glu Tyr Asn Asp Ala

340 345 350Phe Ser Lys Asn Leu Trp Gln Leu Ile Asn Tyr Gln Gly His Gly Ala

355 360 365Ser Ser Glu Lys Leu Val Ser Ser Ala Gly Asn Gly Val Tyr Asp Val

370 375 380Val Tyr Ser Leu Asn Asn Gln Thr Tyr Asn Phe Gln Glu Val Phe Ser385 390 395 400Pro Asn Ser Ile Ser Ile Arg Arg Leu Gly Val Gly Met Val Phe Asp

405 410 415Tyr Val Asp Met Glu Lys Ser Asp Arg Leu Tyr Tyr Gln Asn Ala Leu

420 425 430Gly Phe Met Thr Tyr Met Pro Asn Ser Tyr Asn Asn Asn Leu Gly Asn435 440 445Leu Asn Asn Thr Ile Tyr Tyr Tyr Asp Asn Ser Ile Asp Phe Tyr Ala

450 455 460Ser Gly Lys Thr Leu Phe Thr Lys Ala Glu Phe Ser Gln Thr Phe Thr455 470 475 480Gly Gln Asn Ser Ala Ile Val Phe Gly Ala Lys Asn Ile Trp Thr Ser

485 490 495Val Ser Asp Ala Pro Gln Ser Asn Val Ile Ile Arg Pne Gly Asp Asn

500 505 510Lys Gly Ala Gly Ser Asn Asp Ala Ser Gly His Cys Trp Asn Leu Gln

515 520 525Cys Ile Gly Phe Ile Thr Gly His Tyr Glu Ala Gln Lys Ile Tyr Ile

530 535 540Thr Gly Ser Ile Glu Ser Gly Asn Arg Ile Ser Ser Gly Gly Ala Arg545 550 555 560Ala Leu Ile Leu Thr Gly Phe Lys Ala Phe Phe

565570 (2) information SEQ ID NO 966

Sequence properties:

(A) length: 368 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...368

(xi) sequence representation: SEQ ID NO 966: Met Val Val Leu Gly Ser Thr Gly Ser Ile Gly Lys Asn Ala Leu Lys 151015 Ile Ala Lys Lys Phe Gly Val Lys Ile Glu Ala Leu Ser Cys Gly Lys

20 25 30Asn Ile Ala Leu Ile Asn Glu Gln Ile Lys Val Phe Lys Pro Lys Lys

35 40 45Val Ala Ile Leu Asp Pro Asn Asp Leu Asn Asn Leu Glu Pro Leu Gly

50 55 60Ala Glu Val Phe Val Gly Leu Asp Gly Ile Asp Ala Met Ile Glu Glu65 70 75 80Cys Val Ser Asn Leu Val Ile Asn Ala Ile Val Gly Val Ala Gly Leu

85 90 95Lys Ala Ser Phe Lys Ser Leu Gln Arg Asn Lys Lys Leu Ala Leu Ala

100 105 110Asn Lys Glu Ser Leu Val Ser Ala Gly His Leu Leu Asp Ile Ser Gln

115120 125Ile Thr Pro Val Asp Ser Glu His Phe Gly Leu Trp Ala Leu Leu Gln

130 135 140Asn Lys Thr Leu Lys Pro Lys Ser Leu Ile Ile Ser Ala Ser Gly Gly145 150 155 160Ala Phe Arg Asp Thr Pro Leu Asp Leu Ile Ala Ile Gln Asn Ala Gln

165 170 175Asn Ala Leu Lys His Pro Asn Trp Ser Met Gly Asp Lys Ile Thr Ile

180 185 190Asp Ser Ala Ser Met Val Asn Lys Leu Phe Glu Ile Leu Glu Thr Tyr

195 200 205Trp Leu Phe Gly Ala Ser Leu Lys Ile Asp Ala Leu Ile Glu Arg Ser

210 215 220Ser Ile Val His Ala Leu Val Glu Phe Glu Asp Asn Ser Val Ile Ala225 230 235 240His Leu Ala Ser Ala Asp Met Gln Leu Pro Ile Ser Tyr Ala Ile Asn

245 250 255Pro Lys Leu Ala Ser Leu Ser Ala Ser Ile Lys Pro Leu Asp Leu Tyr

260 265 270Ala Leu Ser Ala Ile Lys Phe Glu Pro Ile Ser Val Glu Arg Tyr Thr

275 280 285Leu Trp Arg Tyr Lys Asp Leu Leu Leu Glu Asn Pro Lys Leu Gly Val

290 295 300Val Leu Asn Ala Ser Asn Glu Val Ala Met Lys Lys Phe Leu Asn Gln305 310 315 320Glu Ile Ala Phe Gly Gly Phe Ile Gln Ile Ile Ser Gln Ala Leu Glu

325 330 335Leu Tyr Ala Lys Lys Ser Phe Lys Leu Ser Ser Leu Asp Glu Val Leu

340345 350Ala Leu Asp Lys Glu Val Arg Glu Arg Phe Gly Ser Val Ala Arg Val

355360365 (2) information of SEQ ID NO:967

Sequence properties:

(A) length: 86 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...86

(xi) sequence representation: SEQ ID NO 967: Met Lys Thr Thr Glu Asn Thr Asp Glu Thr His Leu Arg Glu Thr Lys 151015 Asn Lys Leu Gly Arg Lys Pro Lys Ala Asp Ala Asn Lys Lys Thr Arg

20 25 30Ala Val Ser Leu Tyr Phe Sar Asp Glu Gln Tyr Gln Lys Leu Glu Lys

35 40 45Met Ala Asn Glu Glu Glu Glu Ser Val Gly Ser Tyr Ile Lys Arg Tyr

50 55 60Ile Leu Lys Ala Leu Arg Lys Ile Glu Gln Gly Gly Gly Phe Ile Ala65 70 75 80Phe Asn Leu Phe Leu Ile

85(2) SEQ ID NO 968 message

Sequence properties:

(A) length: 803 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...803

(xi) sequence representation: SEQ ID NO 968 Leu Trp Leu Lys Ser Lys Phe Phe Leu Leu Met Gly Val Gly Leu Leu 151015 Ser His Ser Leu Asn Ala Leu Ser Leu Thr Leu Thr Gln Gly Lys Glu

20 25 30Glu Gly Glu Asp Phe Ser Val Leu Thr Leu Arg Asn Asp Lys Ala Phe

35 40 45Ser Cys Ser Tyr Ala Asn Glu Lys Pro Pro Ser Gly Ile Glu Ala Ser

50 55 60Leu Ser Ile Ile His Ala Lys Arg Pro Ile Glu Cys Val Ile Asp Ser65 70 75 80Ile Pro Lys Glu Gly Phe Thr Pro Leu Glu Asn Ala Phe Phe Asn Ile

85 90 95Thr Tyr Ser Met Arg Gln Gln Gln Phe Ile Leu His Ile Lys Pro Lys

100 105 110Val Met Arg Arg Leu Thr Leu Phe Ser Phe Asp Arg Asp Tyr Lys Lys

115 120 125Ala Ile Pro Leu Phe Val Glu Asn Asp Ala Lys Ala Lys Met Trp Gln

130 135 140Ile Ile Gly Tyr Asp Gln Lys Ile Pro Phe Leu Ser Glu Lys Asp Asn145 150 155 160Ala Gln Lys Gly Leu Asn Phe Pro Ile Ile Ile Lys Asp Ala Gln Thr

165 170 175Pro Ile Ile Gln Glu Leu Asp Val Asn Asn Lys Pro Leu Leu Thr Thr

180 185 190Lys Gly Tyr Asp Leu Asn Ala Tyr Leu Glu Ala Lys Lys Gln Met Asp

195 200 205Ser Gln Ala Tyr Phe Asp Ala Leu Arg Thr Ile Ser Arg Ala Phe Lys

210 215 220Asn Tyr Pro Gln Thr Ile Phe Lys Lys Asp Leu Tyr Leu Leu Glu Ile225 230 235 240Ile Ala Leu Gly Lys Leu Gly Ile Lys Lys Ser Leu Leu Ile Asp Ile

245 250 255Gly Thr Gln Trp Ile Lys Asn Tyr Pro Thr Asp Pro Asn Ile Pro Glu

260 265 270Ala Leu Tyr Tyr Val Ala Lys Ala Leu Asp Glu Asn Asn Asn Tyr Lys

275 280 285Gln Ala Val Arg Tyr Tyr Lys Arg Ile Leu Leu Glu Tyr Lys Asn Ser

290 295 300Arg Tyr Ala Pro Leu Ala Gln Met Arg Leu Ala Ile Glu Ala Ala Glu305 310 315 320Gly Ser Asp Leu Ser Asn Ala Asn Met Leu Phe Lys Glu Ala Phe Ser

325 330 335Asu Ala Lys Asp Lys Glu Ser Ala Ser Glu Ile Ala Leu Asn Trp Ala

340 345 350Glu Ala Glu Ile Asn Tyr Gln Asn Phe Asn Asn Ala Lys Tyr Leu Ile

355 360 365Asp Lys Val Val Gln Ser Asn Pro Asp Tyr Leu Ser Met His Ser Glu

370 375 380Leu Ala Leu Glu Leu Leu Lys Leu Leu Lys Lys Asn Gln Met Asn Glu385 390 395 400Ser Ala Ile Glu Ile Ala His Leu Leu Leu Asn Gln Asp Asp Asp Leu

405 410 415Lys Ala Lys Glu Gln Ala Leu Tyr Asp Leu Gly Ala Leu Tyr Ala Arg

420 425 430Ile Lys Asp Phe Lys Asn Ala His Leu Tyr Asn Leu Gln Tyr Leu Gln

435 440 445Asp His Ala Glu Leu Glu Arg Ala Ser Val Val Arg Ala Arg Asp Glu

450 455 460Lys Ala Leu Phe Ser Met Glu Gly Asn Thr Gln Glu Lys Ile Ala His465 470 475 480Tyr Asp Lys Ile Ile Gln Asn Phe Pro Asn Ser Asn Glu Ala Gln Lys

485 490 495Ala Leu Glu Leu Lys Ala Gln Leu Leu Phe Asp Asn Lys His Tyr Ala

500 505 510Glu Val Leu Gly Met Gln Lys Asn Leu Pro Lys Asp Ser Pro Leu Ile

515 520 525Gln Lys Thr Leu Asn Ile Leu Ala Lys Thr Pro Leu Glu Asp His Arg

530 535 540Cys Lys Glu Ala Leu Lys Tyr Leu Ser Gln Ile Thr Ala Phe Ala Phe545 550 555 560Asn Pro Gln Glu Glu Ile Gln Ala Phe Asp Cys Leu Tyr Phe Ala Ser

565 570 575Leu Lys Glu Lys Ala Gln Ile Ile Ala Leu Asn Ala Leu Lys Ala Ala

580 585 590Lys Thr Pro Ser Glu Lys Leu Thr Trp Leu Tyr Arg Leu Gly Arg Asn

595 600 605Tyr Tyr Arg Leu Gly Asp Phe Lys Asn Ser Thr Leu Ala Ser Lys Asp

610 615 620Ala Leu Ile Leu Ala Gln Ser Leu Asn Lys Lys Glu Phe Tyr Asp Ile625 630 635 640Ala Phe Val Leu Phe Ser Asp Tyr Met Gln Asn Asn Glu Lys Gly Leu

645 650 655Ala Leu Asn Leu Tyr Ala Phe Leu Glu Lys His Phe Lys Asp Asp Lys

660 665 670Arg Met Ala Leu Val Tyr Phe Lys Leu Leu Glu Asn Glu Lys Asp Pro

675 680 685Lys Ser Val Lys Ile Tyr Ala Thr Ser Leu Leu Lys Leu Gln Asp Ala

690 695 700Tyr Lys Asp Tyr Ser Tyr Thr Pro Phe Gly Glu Phe Ala Leu Ile Asp705 710 715 720Ala Tyr Arg Thr Thr Lys Asp Tyr Ser Lys Ala Leu Glu Thr Leu Asp

725 730 735Lys Leu Leu Asn Arg Arg Leu Ser Leu Glu Asp His Gln Lys Ala Leu

740 745 750Tyr Leu Gln Ser Ser Leu Leu Asp Leu Thr Asn Gln Lys Ala Lys Ser

755 760 765Lys Ala Ser Leu Glu Lys Cys Val Gln Leu Lys Gln Lys Asp Gln Thr

770775780 Asn Ala Trp Gln Asn Leu Cys Glu Gln Gly Leu Asn Leu Phe Lys Asn 785790795800 Lys Glu Ser (2) SEQ ID NO:969 information

Sequence properties:

(A) length: 265 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...265

(xi) sequence representation: SEQ ID NO 969: Met Ile Leu Arg Ala Ser Val Leu Ser Ala Leu Leu Leu Val Gly Leu 151015 Gly Ala Ala Pro Lys His Ser Val Ser Ala Ser Asp Lys Arg Met Gln

20 25 30Asp Asn Leu Val Ser Val Ile Glu Lys Gln Thr Asn Lys Lys Val Arg

35 40 45Ile Leu Glu Ile Lys Pro Leu Lys Ser Ser Gln Asp Leu Lys Met Val

50 55 60Val Ile Glu Asp Pro Asp Thr Lys Tyr Asn Ile Pro Leu Val Val Ser65 70 75 80Lys Asp Gly Asn Ser Val Ile Gly Leu Ser Asn Ile Phe Phe Ser Asn

85 90 95Lys Ser Asp Asp Val Lys Leu Val Ala Glu Thr Asn Gln Lys Ile Gln

100 105 110Ala Leu Asn Ala Thr Gln Gln Asn Ser Ala Lys Leu Asn Ala Ile Phe

115 120 125Asn Glu Ile Pro Ala Asp Tyr Ala Ile Glu Leu Pro Ser Thr Asn Ala

150 135 140Glu Asn Lys Asp Lys Ile Leu Tyr Ile Val Ser Asp Pro Met Cys Pro145 150 155 160His Cys Gln Lys Glu Leu Thr Lys Leu Arg Asp His Leu Lys Glu Asn

165 170 175Thr Val Arg Met Val Val Val Gly Trp Leu Gly Val Asn Ser Ala Lys

180 185 190Lys Ala Ala Leu Ile Gln Glu Glu Met Ala Lys Ala Arg Ala Arg Gly

195200 205Ala Ser Val Glu Asp Lys Ile Ser Ile Leu Glu Lys Ile Tyr Ser Thr

210 215 220Gln Tyr Asp Ile Asn Ala Gln Lys Glu Pro Glu Asp Leu Arg Thr Lys225 230 235 240Val Glu Asn Thr Thr Lys Lys Ile Phe Glu Ser Gly Val Ile Lys Gly

245 250 255Val Pro Phe Leu Tyr His Tyr Lys Ala

260265 (2) SEQ ID NO:970 message

Sequence properties:

(A) length: 227 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...227

(xi) sequence representation: SEQ ID NO:970: Leu Asp Phe Lys Ala Ile Glu His Gly Glu Glu Thr Leu Lys Asn Glu 151015 Thr Leu Arg Ala Leu Ser Asp Phe Ala Lys Ser Ser Asp Thr His Ile

20 25 30Val Ala Cys Ser Ile Glu Lys Asn Asn Lys Lys Leu Tyr Asp Ser Ala

35 40 45Tyr Ile Ile Pro Pro Lys Gly Lys Ile Val Gly Lys His Arg Lys Ile

50 55 60Tyr Leu Trp Gly Asp Glu Lys Ser Arg Phe Lys Arg Gly Lys Lys Tyr65 70 75 80Glu Val Phe Thr Leu Asp Phe Gly Asp Phe Ser Ala Lys Val Gly Leu

85 90 95Gln Ile Cys Tyr Glu Thr Gly Phe Gly Val Gly Ala Asn Leu Leu Val

100 105 110Leu Gln Gly Ala Glu Val Leu Ile Tyr Pro Ser Ala Phe Gly Lys Ala

115 120 125Arg Ala Tyr Asn Trp Asp Leu Leu Ser Lys Ala Arg Ala Leu Glu Asn

130 135 140Gly Cys Phe Val Cys Ala Cys Asn His Ser Gly Glu Glu Thr Asn Ala145 150 155 160Lys Leu Lys Gln Thr Leu Glu Phe Ala Gly Asp Ser Arg Ile Ile Ala

165 170 175Pro Asn Gly Lys Ile Ile Ala Gln Ala Thr Lys Leu Asn Glu Val Ile

180 185 190Ile Ala Glu Met Asp Leu Asn Glu Val Ala Leu Gln Arg Gln Lys Ile

195 200 205Pro Tyr Leu Gln Asp Phe Asp Thr Lys Leu Thr Lys Lys Gly Phe Gly

210215220 Lys Leu Thr225(2) SEQ ID NO:971 information

Sequence properties:

(A) length: 293 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...293

(xi) sequence representation: 971: Met Ala Lys Glu Ile Leu Val Ala Tyr Gly Val Asp Ile Asp Ala Val 151015 Ala Gly Trp Leu Gly Ser Tyr Gly Gly Glu Asp Ser Pro Asp Asp Ile SEQ ID NO

20 25 30Ser Arg Gly Leu Phe Ala Gly Glu Val Gly Ile Pro Arg Leu Leu Lys

35 40 45Leu Phe Lys Lys Tyr His Leu Pro Ala Thr Trp Phe Ala Pro Gly His

50 55 60Ser Ile Glu Thr Phe Pro Glu Pro Met Lys Met Ile Val Asp Ala Gly65 70 75 80His Glu Val G1y Ala His Gly Tyr Ser His Glu Asn Pro Ile Ala Met

85 90 95Thr Ala Lys Gln Glu Glu Asp Val Leu Leu Lys Ser Val Glu Leu Ile

100 105 110Lys Asp Leu Thr Gly Lys Ala Pro Thr Gly Tyr Val Ala Pro Trp Trp

115 120 l25Glu Phe Ser Asn Ila Thr Asn Glu Leu Leu Leu Lys His Gly Phe Lys

130 135 140Tyr Asp His Ser Leu Met His Asn Asp Phe Thr Pro Tyr Phe Val Arg145 150 155 160Val Gly Asp Ser Trp Ser Lys Ile Asp Tyr Ser Leu Glu Ala Lys Asp

153 170 175Trp Met Lys Pro Leu Ile Arg Gly Val Glu Thr Asn Leu Val Glu Ile

180 155 190Pro Ala Asn TrP Tyr Leu Asp Asp Leu Pro Pro Met Met Phe Ile Lys

195 200 205Lys Ser Pro Asn Ser Phe Gly Phe Val Ser Pro Arg Asp Ile Gly Gln

210 215 220Met Trp Ile Asp Gln Phe Asp Trp Val Tyr Arg Glu Met Asp Tyr Ala225 230 235 240Val Phe Ser Met Thr Ile His Pro Asp Val Ser Ala Arg Pro Gln Val

245 250 255Leu Leu Met His Glu Lys Ile Ile Glu His Ile Asn Gln His Glu Gly

260 265 270Val Arg Trp Val Thr Phe Asn Glu Ile Ala Asp Asp Phe Leu Lys Arg

275 280 285Asn Pro Arg Lys Lys

290(2) SEQ ID NO 972 information

Sequence properties:

(A) length: 136 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...136

(xi) sequence representation: SEQ ID NO:972: Val Cys Gly Val Leu Ser Leu Gln Ala Arg Leu Ser Phe Glu Asn Cys 151015 Ser Lys Pro Leu Asp Cys Ser Leu Phe Ala Thr Thr Cys Thr Pro Gln

20 25 30Asn Pro Ile Gly Ser Cys Met Val Ser Ser Gln Gly Gly Val Cys Gly

35 40 45Val Leu Ser Leu Gln Ala Arg Leu Ser Phe Glu Asn Cys Ser Lys Pro

50 55 60Leu Asp Cys Ser Leu Phe Ala Thr Thr Cys Thr Pro Gln Asn Pro Ile65 70 75 80Gly Ser Cys Met Val Ser Ser Gln Gly Gly Val Arg Gly Val Leu Ser

85 90 95Leu Gln Ala Arg Leu Ser Phe Lys Asn Cys Phe Leu Val Lys Ser Leu

100 105 110Lys Pro Ser Gln Leu Thr Leu Met Leu Thr Gly Phe Leu Gly Gly Phe

115 120 125Ser Phe Leu Thr Thr Gly Phe Trp

130135 (2) SEQ ID NO 973 information

Sequence properties:

(A) length: 360 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...360

(xi) sequence representation: 973: Met Asn Gly Phe Cys Ala Arg Leu Arg Ala Ile Thr Phe Asn Glu Arg 151015 Leu Lys Met Lys Ile Ala Val Lsu Leu Ser Gly Gly Val Asp Ser Ser SEQ ID NO

20 25 30Tyr Ser Ala Tyr Ser Leu Lys Glu Gln Gly His Glu Leu Val Gly Ile

35 40 45Tyr Leu Lys Leu His Ala Ser Glu Lys Lys His Asp Leu Tyr Ile Lys

50 55 60Asn Ala Gln Lys Ala Cys Glu Phe Leu Gly Ile Pro Leu Glu Val Leu6570 75 80Asp Phe Gln Lys Asp Phe Lys Ser Ala Val Tyr Asp Glu Phe Ile Asn

85 90 95Ala Tyr Glu Glu Gly Gln Thr Pro Asn Pro Cys Ala Leu Cys Asn Pro

100 105 110Leu Met Lys Phe Gly Leu Ala Leu Asp His Ala Leu Lys Leu Gly Cys

115 120 125Glu Lys Ile Ala Thr Gly His Tyr Ala Arg Val Lys Glu Ile Asp Lys

130 135 140Val Ser Tyr Ile Gln Glu Ala Leu Asp Lys Thr Lys Asp Gln Ser Tyr145 150 155 160Phe Leu Tyr Ala Leu Glu His Glu Val Ile Ala Lys Leu Val Phe Pro

165 170 175Leu Gly Asp Leu Leu Lys Lys Asp Ile Lys Pro Leu Ala Leu Asn Ala

180 185 190MeC Pro Phe Leu Gly Thr Leu Glu Thr Tyr Lys Glu Ser Gln Glu Ile

195 200 205Cys Phe Val Glu Lys Ser Tyr Ile Asp Thr Leu Lys Lys His Val Glu

210 215 220Val Glu Lys Glu Gly Val Val Lys Asn Leu Gln Gly Glu Val Ile Gly225 230 235 240Thr His Lys Gly Tyr Met Gln Tyr Thr Ile Gly Lys Arg Lys Gly Phe

245 250 255Ser Val Lys Gly Ala Leu Glu Pro His Phe Val Val Gly Ile Asp Ala

260 265 270Lys Lys Asn Glu Leu Ile Val Gly Lys Lys Glu Asp Leu Ala Thr His

275 280 285Ser Leu Lys Ala Lys Asn Lys Ser Leu Thr Lys Asp Phe Lys Asp Gly

290 295 300Glu Tyr Phe Ile Lys Ala Arg Tyr Arg Ser Val Pro Thr Lys Ala Phe305 510 315 320Val Ser Leu Lys Asp Gly Met Ile Glu Val Glu Phe Lys Glu Pro Phe

325 330 335Tyr Gly Val Ala Lys Gly Gln Ala Leu Val Val Tyr Lys Asp Asp Ile

340 345 350Leu Leu Gly Gly Gly Val Ile Val

335360 (2) SEQ ID NO 974 information

Sequence properties:

(A) length: 357 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...357

(xi) sequence representation: 974: Met Lys Ala Ser Ile Tyr Asp Phe Thr Leu Asp Glu Leu Ser Gln Leu 151015 Leu Lys Pro Ser Phe Arg Ala Lys Gln Lau Tyr Leu Trp Leu Tyr Ala SEQ ID NO

20 25 30Lys Tyr Lys Thr Ser Phe Lys Asp Met Gln Asn Asn Phe Ser Lys Asp

35 40 45Phe Ile Ala Tyr Leu Glu Gln Glu Phe Thr Leu Arg Thr Ile Glu Ile

50 55 60Ala His Val Arg Glu Ser Val Asp Gly Ser Lys Lys Tyr Leu Phe Lys65 70 75 80SerLeu Arg Asp Asn His Thr Phe Glu Ala Val Leu Leu Lys Met Lys

85 90 95Asp Lys Lys Ile Asp Glu Glu Thr Asn Ala Val Leu Glu Gly Glu Lys

100 105 l10Tyr Thr Val Cys Val Ser Cys Gln Ile Gly Cys Gln Val Gly Cys Ser

115 120 125Phe Cys Phe Thr Gln Lys Gly Gly Phe Val Arg Asp Leu Lys Ala Ser

130 135 140Glu Ile Ile Gln Gln Ala Leu Leu Ile Lys Glu Ala Asn Asn Leu Pro145 150 155 160Ile Glu Lys Ala Leu Asn Ile Val Phe Met Gly Met Gly Glu Pro Leu

165 170 175Asn Asn Leu Asp Glu Val Cys Lys Ala Val Glu Ile Phe Asn Thr Gly

180 185 190Met Gln Ile Ser Pro Lys Arg Ile Thr Ile Ser Thr Ser Gly Val Ala

195 200 205Asp Lys Ile Pro Ile Leu Ala Gly Lys Asn Leu Gly Val Gln Leu Ala

210 215 220Ile Ser Leu His Ala Val Asp Asp Lys Thr Arg Ser Ser Leu Met Pro225 230 235 240Leu Asn Lys Lys Tyr Asn Ile Glu Cys Val Leu Asn Glu Val Arg Lys

245 250 255Trp Pro Leu Glu Gln Arg Lys Arg Val Met Phe Glu Tyr Leu Leu Ile

260 265 270Lys Asp Leu Asn Asp Ser Leu Asp Cys Ala Lys Lys Leu Leu Lys Leu

275 280 285Leu Asn Gly Ile Lys Ser Lys Val Asn Leu Ile Leu Phe Asn Pro His

290 295 300Glu Gly Ser Lys Phe Glu Arg Pro Ser Leu Glu Ser Ala Arg Met Phe305 310 315 320Ala Asp Phe Leu Asn Ala Lys Gly Leu Leu Cys Thr Ile Arg Glu Ser

325 330 335Lys Ala Leu Asp Ile Glu Ala Ala Cys Gly Gln Leu Arg Glu Lys Lys

340 345 350Leu Gln Gln Lys Ile

355(2) SEQ ID NO 975 information

Sequence properties:

(A) length: 468 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...468

(xi) sequence representation: 975: Met Ala Glu Trp Lys Thr Asp Thr Glu Glu Val Lys Lys Val Val Gly 15I 015 Arg Cys Arg Glu Phe Lys Arg Ser Leu Gln Glu Glu Lys Cys Ser Pro SEQ ID NO

20 25 30Phe Ile Lys Asp Leu Asp Ser Tyr Ala Leu Lys Ile Ile Val Glu Arg

35 40 45Arg Lys Thr Glu Met Gln Leu Glu Lys Ala Ile Gly Glu Lsu Lys Lys

50 55 60Ala Lys Ser Asn Glu Asp Asp Ala Lys Val Ala Leu Arg Val Leu Gln65 70 75 80Gly Ala Ser Val Val Ser Trp Ile Trp Pro Pro Ala Arg Ile Ala Ala

85 90 95Thr Ala Ala Ile Val Ala Ala Glu Ala Val Leu Lys Phe Met Lys Glu

100 105 110Asp Thr Glu Lys Cys Lys Arg Asn Val Glu Leu Leu Glu Arg Met Leu

115 120 125Glu Ile Tyr Ser Asn Gln Ala Lys Ala Ser Ala Asn Leu Met Asn Gln

130 135 140Ala Trp Glu Gly Ile Lys Lys Arg Leu His Phe Tyr Thr Asp Lys His145 150 155 160Gln Glu Phe Ile Arg Arg Leu Lys Gln Ala Ser Asp Ala Ile Asp Asn

165 170 175Glu Tyr Asn Phe Pro Thr Pro Gly Val Leu Leu Glu Tyr Asp Phe Glu

180 185 190Arg Pro Ala Ile Ser Tyr Thr Pro Lys Lys Ser Val Phe Asn Glu Arg

195 200 205Leu Lys Asp Leu Arg Glu Asn Phe Ser Ala Ser Leu Tyr Ala Asp Leu

210 215 220883Lys Asp Lys Ile His His Asn Ala Leu Ser Asn Asp Asp Leu Glu Arg225 230 235 240Met Ile Ala Phe Arg Glu Gln Glu Phe Glu Lys Ser Leu Glu Asp Trp

245 250 255Met Gly Ala Tyr Ser Tyr Asp Glu Asn Pro Asn Asp Glu Leu Asp Arg

260 265 270Met Ala Ile Ser Lys Glu Gln Glu Leu Glu Lys Ser Leu Glu Asp Leu

275 280 285Met Pro Ser Val Leu Gly Val Pro Ser Tyr Asn Glu Ser Leu Thr Leu

290 295 300Ala Lys Asn Arg Cys Val Lys Asn Phe Lys Glu Ala Leu Glu Gly Phe305 310 315 320Thr Glu Lys Ile Lys Glu Ser Pro Asn Asp Ser Asn Ala Ile Asn Glu

325 330 335Ala Phe Asp Asn Leu Glu Thr Glu Leu Glu Arg Ala Thr Glu Asn Leu

340 345 350Ser Gln Lys Ile Asp Pro Val Leu Glu Arg Asn Glu Asn Tyr Thr Gln

355 360 365Lys Ala Leu Glu Tyr Arg Glu Phe Leu Glu Ser Arg Lys Glu Ser Phe

370 375 380Ile Val Asp Glu Lys Asn Pro Tyr Pro Glu Glu Val Ser Phe Ash Glu385 390 395 400Trp Arg Trp Ala Glu Phe Asp Ser Val Phe Ser Ala Ile Val Pro Leu

405 410 415Glu Asp Leu Asn Lys Thr Ala Cys Ala His His Ala Leu Lys Ala Leu

420 425 430Gln Ala Thr Leu Lys Thr Thr Ile Trp Ala Leu Met Arg Gln Ser Trp

435 440 445Asn Arg Ser Gln Lys Asp Ser Ser Leu Gly Gly Ile Cys Gly Ile Leu

450455460 Thr Arg Met Phe465(2) SEQ ID NO:976 information

Sequence properties:

(A) length: 268 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...268

(xi) sequence representation: 976: Met Lys Gln Ser Leu ArG Glu Gln Lys Leu Leu Lys Ile Leu Glu Asn 151015 Asp Val Leu Thr Ile Leu Asp Ser Phe Ser Asn Tyr Leu Phe Glu Leu SEQ ID NO

20 25 30Arg Glu Glu Leu Asp Phe Ile Glu Glu Glu Met Glu Gly Glu Ile Thr

35 40 45Glu Gln Asn Leu Thr Ala Leu Tyr Asp Phe Ser Asn Phe Leu Glu Asp

50 55 60His Val Asn Val Phe Tyr Glu Asn Val Leu Asn Ile Asp Asp Val Lys65 70 75 80Thr Glu His Leu Tyr Ser Gly Leu Ile Asp Ser Leu Asn Ala Asn Leu

85 90 95His Phe Val Lys Ser Phe Leu Ser Asn Gln Asp Leu Asp Phe Arg Phe

100 105 110Phe Lys Glu Ile Asn Asp Gly Gln Asp Pro Gln Lys Thr Leu Ser Arg

115 120 125Leu Ile Pro Leu Gln Ser Gly Lys Asn Asp Ala Ser Ser Phe Lys Ala

130 135 140Asn Asn Ser Phe Val Ser Leu Val Tyr Val Tyr Ala Tyr Phe Met Leu145 150 155 160Glu Thr Ile Ar9 Gln Ser Tyr Arg Ile Leu Arg Leu Leu Glu Lys Pro

165 170 175Ile Asn Asn Asn Ile Ser Glu Asp Met Gln Ser Asp Ile Glu Asn Phe

180 185 190Phe Val Gln Ala Asn Phe Leu Glu Tyr Tyr Val GLn Asn Lys Ile Tyr

195 200205Pro Thr ASn His Ala Tyr Asp Phe Thr His Leu Ile Met Asp Ser Ile

210 215 220Ile Pro Asn Trp Ile Gln Ile Asp Met Ser Val Glu Ala Lys Lys Lys225 230 235 240Glu Leu Phe Glu Lys Tyr Phe Gln Asn Ile Asp Glu Val Thr Asn Lys

245 250 255Met Leu Asp Gln Glu Asn Gln Asn Lys Asn Ser Asp

260265 (2) SEQ ID NO 977 information

Sequence properties:

(A) length: 258 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...258

(xi) sequence representation: 977: Leu Leu Ser Asn Lys Thr Leu Pro Lys Arg Phe Ala Thr Tyr Ser Leu 151015 Gln Glu Val Gly Val Ile Phe Leu Thr Thr Gln Ile Leu Ser Ile Met SEQ ID NO

20 25 30Arg Lys Thr Arg Cys Ser Lys Thr Leu Phe Phe Ile Thr Arg Gly Arg

35 40 45Glu Ser Phe Arg Tyr Gln Leu Cys Asp His Tyr Lys Gln Lys Arg His

50 55 60Gln Phe Asp Glu Asp Phe Arg Ser Leu Leu Lys Ala Leu Lys Ile Ala65 70 75 80Leu Val Glu Lys Tyr Pro Leu Lys Lys Gly Ala Lys Ile Gln Gly Glu

85 90 95His Cys Phe Glu Tyr Glu Ala Asp Asp Ile Ile Ser Phe Tyr Lys Lys

100 105 l10Lys Asp Pro Asn Asn Tyr Val Ile Ala Ser Met Asp Lys Asp Ile Leu

115 120 125Tyr Ser Asn Arg Gly Ser His Phe Asn Leu Lys Thr Asn Ala Phe Phe

130 135 140Asn Val Ser Gln Lys Glu Ala His Phe Phe Ala Tyr Tyr Gln Cys Val145 150 155 160Val Gly Asp Lys Gly Asp Asn Ile Lys Gly Val Lys Gly Ile Gly Gly

165 170 175Phe Asn Tyr Lys Asp Phe Leu Asn Glu Asp Ala Lys Glu His Glu Leu

180 185 190Trp Glu Gln Ile Ile Gln Ala Phe Lys Ile Lys Glu Asp Leu Ser Asp

195 200 205Ser Glu Ala Lys Glu Lys Ala Leu Leu Asn Met Ar9 Leu Val Asn Met

210 215 220His Gln Met Thr His His Gly Val Ile Lys Leu Trp Glu Pro Glu Phe225 230 235 240Lys Lys Ala Phe Phe Pro Lys Lys Pro Gln Ar9 Pro Asp Phe Lys Arg

245250255 Ile Ser (2) SEQ ID NO:978 information

Sequence properties:

(A) length: 256 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...256

(xi) sequence representation: 978: Leu Cys Leu Lys Leu Leu Ile Trp Asn Phe Lys Glu His Ser Leu Lys 151015 Val Asn Phe Phe Ala Thr Cys Leu Gly Ala Ala Ile Tyr Ser Asn Ala SEQ ID NO

20 25 30Ser Leu Asn Ala Ile Lys Leu Leu Arg Lys Glu Asn Leu Glu Val Val

35 40 45Phe Lys Lys Asp Gln Thr Cys Cys Gly Gln Pro Ser Tyr Asn Ser Gly

50 55 60Tyr Tyr Glu Glu Thr Lys Lys Val Val Leu Tyr Asn Ile Lys Leu Tyr65 70 75 80Ser Asn Asn Asp Tyr Pro lle Ile Leu Pro Ser Gly Ser Cys Thr Gly

85 90 95Met Met Arg His Asp Tyr Leu Glu Leu Phe Glu Gly His Ala Glu Phe

100 105 110Asn Met Val Lys Asp Phe Cys Ser Arg Val Tyr Glu Leu Ser Glu Phe

115 120 125Leu Asp Lys Lys Leu Gln Val Lys Tyr Glu Asp Lys Gly Glu Pro Leu

130 135 140Lys Ile Thr Trp His Ser Asn Cys His Ala Leu Arg Val Ala Lys Val145 150 155 160Ile Asp Ser Ala Lys Asn Leu Ile Arg Gln Leu Lys Asn Val Glu Leu

165 170 175Ile Glu Leu Glu Lys Glu Glu Glu Cys Cys Gly Phe Gly Gly Thr Phe

180 185 190Ser Val Lys Glu Pro Glu Ile Ser Ala Val Met Val Lys Glu Lys Ile

195 200 205Lys Asp Ile Glu Ser Arg His Val Asp Val Ile Val Ser Ala Asp Ala

210 215 220Gly Cys Leu Met Asn Ile Ser Thr Ala Met Gln Lys Met Gly Ser Leu225 230 235 240Thr Lys Pro Met His Phe Tyr Asp Phe Leu Ala Ser Arg Leu Gly Leu

2456250255 (2) SEQ ID NO 979 information

Sequence properties:

(A) length: 469 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...469

(xi) sequence representation: 979: Leu Lys Ile Phe Val Leu Leu Met Ser Val Ile Leu Gly Ile Ser Leu 151015 Thr Gly Cys Ile Gly Tyr Arg Met Asp Leu Glu His Phe Asn Thr Leu SEQ ID NO

20 25 30Tyr Tyr Glu Glu Ser Pro Lys Lys Ala Tyr Glu Tyr Ser Lys Gln Phe

35 40 45Thr Lys Lys Lys Lys Asn Ala Leu Leu Trp Asp Lau Gln Asn Gly Leu

50 55 60Ser Ala Leu Tyr Ala Arg Asp Tyr Lys Thr Ser Leu Gly Val Leu Asp65 70 75 80Gln Ala Glu Gln Arg Phe Asp Lys Thr Gln Ser Ala Phe Thr Arg Gly

85 90 95Ala Gly Tyr Val Gly Ala Thr Met Ile Asn Asp Asn Val Arg Ala Tyr

100 105 110Gly Gly Asn Ile Tyr Glu Gly Val Leu Ile Asn Tyr Tyr Lys Ala Ile

115 120 125Asp Tyr Met Leu Leu Asn Asp Ser Ala Lys Ala Arg Val Gln Phe Asn

130 135 140Arg Ala Asn Glu Arg Gln Arg Arg Ala Lys Glu Phe Tyr Tyr Glu Glu145 150 155 160Val Gln Lys Ala Ile Lys Glu Ile Asp Ser Ser Lys Lys His Asn Ile

165 170 175Asn Met Glu Arg Ser Arg Ala Glu Val Ser Glu Ile Leu Asn Asn Thr

180 185 190Tyr Ser Asn Leu Asp Lys Tyr Glu Ala Tyr Gln Gly Leu Leu Asn Pro

195 200 205Ala Val Ser Tyr Leu Ser Gly Leu Phe Tyr Ala Leu Asn Gly Asp Lys

210 215 220Asn Lys Gly Leu Gly Tyr Leu Asn Glu Ala Tyr Gly Ile Ser Gln Ser225 230 235 240Pro Phe Val Ala Gln Asp Leu Val Phe Phe Lys Asn Pro Asn Arg Ser

245 250 255His Phe Thr Trp Ile Ile Ile Glu Asp Gly Lys Glu Pro Gln Lys Ser

260 265 270Glu Phe Lys Ile Asp Val Pro Ile Phe Met Ile Asp Ser Val Tyr Ash

275 280 285Val Ser Val Ala Leu Pro Lys Leu Glu Lys Gly Glu Ala Phe Tyr Gln

290 295 300Asn Phe Thr Leu Lys Asp Gly GluLys Val Thr Pro Phe Asp Thr Leu305 310 315 320Ala Ser Ile Asp Ala Val Val Ala Ser Glu Phe Arg Lys Gln Leu Pro

325 330 335Tyr Ile Ile Thr Arg Ala Ile Leu Ser Ala Thr Phe Lys Val Gly Met

340 345 350Gln Ala Val Ala Asn Tyr Tyr Leu Gly Phe Val Gly Gly Leu Val Thr

355 360 365Ser Leu Tyr Ser Gly Val Ser Thr Phe Ala Asp Thr Arg Asn Thr Ser

370 375 380Ile Phe Ala His Lys Ile Tyr Leu MeL Arg Ile Lys Asn Lys Ala Phe385 390 395 400Glu Ser Tyr Glu Val Arg Ala Asp Ser Ile Asp Ala Phe Ser Phe Ser

405 410 415Leu Lys Pro Cys Lys Arg Ser Leu Glu Ser Pro Lys Ile Ile Asp Ala

420 425 430Arg Glu Leu Leu Ser Gly Phe Val Thr Ala Pro Gln Val Phe Cys Ser

435 440 445Asn Arg His Asn Ile Leu Tyr Val Arg Ser Phe Lys Asn Gly Phe Val

450455460 Leu Ser His Leu Lys465(2) SEQ ID NO:980 information

Sequence properties:

(A) length: 350 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...350

(xi) sequence representation: SEQ ID NO 980: Met Lys Gln Ile Lys Ala Leu Ala Leu Phe Ser Gly Gly Leu Asp Ser 151015 Leu Leu Ser Met Lys Leu Leu Ile Asp Gln Gly Ile Glu Val Thr Ala

20 25 30Leu His Phe Asn Ile Gly Phe Gly Gly Asn Lys Asp Lys Arg Glu Tyr

35 40 45Phe Glu Asn Ala Thr Ala Gln Ile Gly Ala Lys Leu Leu Val Cys Asp

50 55 60Ile Arg Glu Gln Phe Phe Asn Asp Val Leu Phe Lys Pro Lys Tyr Gly65 70 75 80Tyr Gly Lys Tyr Phe Asn Pro Cys Ile Asp Cys His Ala Asn Met Phe

85 90 95Arg Asn Ala Phe Tyr Lys Met Leu Glu Leu Asp Ala Asp Phe Val Leu

100 105 110Ser Gly Glu Val Leu Gly Gln Arg Pro Lys Ser Gln Arg Lys Glu Ala

115 120 125Leu Asn Gln Val Arg Lys Leu Val Arg Glu Val Gly Glu Glu Ala Arg

130 135 140Phe Asp Leu Ile Leu Asp Arg Thr Gln Ala Ser Gly Glu Lys Pro Gln145 150 155 160Phe Leu Asp Glu Leu Leu Leu Arg Pro Met Ser Ala Lys Leu Leu Glu

165 170 175Pro Thr Phe Met Glu Lys Lys Gly Trp Val Asp Arg Glu Lys Leu Leu

180 185 190Asp Val Ser Gly Arg Gly Arg Ala Arg Gln Leu Gln Met Ile Lys Asp

195 200 205Tyr Gly Leu Lys Tyr TyrGlu Lys Pro Gly Gly Gly Cys Leu Leu Thr

210 215 220Asp Ile Gln Val Ser Asn Lys Ile Lys Asn Leu Lys Glu Tyr Arg Glu225 230 235 240Met Val Phe Glu Asp Gly Val Ile Val Lys Asn Gly Arg Tyr Phe Val

245 250 255Leu Pro His Asn Ala Arg Leu Val Val Ala Arg Asn Glu Glu Glu Asn

260 265 270His Lys Leu Asp Ile Glu His Pro Leu Met Asp Lys Ile Glu Leu Leu

275 280 285Gly Cys Lys Gly Pro Leu Ser Leu Val Asp Lys Asn Ala Ser Gln Glu

290 295 300Asp Lys Glu Leu Ala Gly Arg Ile Ala Leu Gly Tyr Ala Lys Thr Leu305 310 315 320Lys Asn Gln Ala Tyr Leu Ile Gln Ile Gly Asn Glu Lys Arg Glu Leu

325 330 335Tyr Pro Leu Asp Lys Glu Asn Ala Arg Glu Tyr Leu Phe Ala

340345350 (2) SEQ ID NO:981 information

Sequence properties:

(A) length: 405 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...405

(xi) sequence representation: SEQ ID NO:981: Met Lys Lys Tyr Ser Ala Ile Pro Thr Pro Cys Tyr Ala Leu Glu Ser 151015 Glu Arg Leu Glu Lys Asn Ala Lys I1e Leu Glu Ile Val Arg Gln Gln

20 25 30Ser Gly Ala Lys Val Leu Leu Ala Leu Lys Gly Tyr Ala Phe Trp Arg

35 40 45Glu Phe Gly Ile Leu Arg Gln Lys Leu Asn Gly Cys Cys Ala Ser Gly

50 55 60Leu Tyr Glu Ala Lys Leu Ala Phe Glu Glu Phe Gly Gly Arg Glu Ser65 70 75 80His Lys Glu Ile Cys Val Tyr Ser Pro Ala Phe Lys Glu Ala Glu Met

85 90 95Ser Ala Ile Leu Pro Leu Ala Thr Ser Ile Ile Phe Asn Ser Phe His

100 105 110Gln Tyr Ala Thr Tyr Lys Asp Arg Ile Leu Asp Lys Asn Lys Gln Leu

115 120 125Glu Asn Leu Gly Leu Ser Pro Ile Lys Met Gly Leu Arg Ile Asn Pro

130 135 140Leu Tyr Ser Glu Val Thr Pro Ala Ile Tyr Asn Pro Cys Ser Lys Met145 150 155 160Ser Arg Leu Gly Ile Thr Pro Ser Gly Phe Glu Lys Gly Val Lys Glu

165 170 175His Gly Leu Glu Gly Val Ser Gly Leu His Phe His Thr His Cys Glu

180 185 190Gln Asn Ala Asp Ala Leu Cys Arg Thr Leu Glu His Val Glu Arg His

195 200 205Phe Lys Pro Tyr Leu Glu Asn Met Ala Trp Val Asn Phe G1y Gly Gly

210 215 220His His Ile Thr Arg Ser Asp Tyr Asp Val Asn Leu Leu Ile Gln Thr225 230 235 240Ile Lys Asp Phe Lys Glu Arg Tyr His Asn Thr Glu Val Ile Leu Glu

245 250 255Pro Gly Glu Ala Ile Gly Trp Gln Cys Gly Phe Leu Ile Ala Ser Val

260 265 270Ile Asp Ile Val Gln Asn Asp Gln Glu Ile Ala Ile Leu Asp Ala Ser

275 280 285Phe Ser Ala His Met Pro Asp Cys Leu Glu Met Pro Tyr Arg Pro Ser

290 295 300Ile Leu Lys Val Ser Val Glu Asn Asp Glu Glu Ile Ile Glu Val Glu305 310 315 320Lys Gly Glu Asn Gln Gly Ala Phe Ser Tyr Phe Leu Gly Gly Pro Thr

325 330 335Cys Leu Ala Gly Asp Phe Met Gly Ser Phe Ser Phe Glu Thr Pro Leu

340 345 350Lys Arg Gly Asp Lys Ile Val Phe Gln Asp Met Leu His Tyr Thr Ile

355 360 365Val Lys Asn Asn Ser Phe Asn Gly Val Pro Leu Pro Ser Leu Ala Lys

370 375 380Ile Asp Ser Gln Gly Phe Lys Ile Leu Lys Ser Phe Ser Tyr Glu Asp385 390 395 400Tyr Lys Asn Arg Asn

405(2) SEQ ID NO 982 information

Sequence properties:

(A) length: 321 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...321

(xi) sequence representation: SEQ ID NO:982: Met Ala Asp Ser Leu Ala Gly Ile Asp Gln Val Thr Ser Leu His Lys 151015 Asn Asn Glu Leu Gln Leu Leu Cys Phe Arg Leu Gly Lys Asn Lys Asp

20 25 30Leu Tyr Ala Val Asn Val Phe Lys Ile Arg Glu Val Val Lys Tyr His

35 40 45Gly Asn Leu Thr Ile Ile Ser His Glu Asn Asn Ser Leu Val Glu Gly

50 55 60Leu Ile Ile Ile Arg Glu Leu Thr Ile Pro Leu Ile Asp Met Lys Lys65 70 75 80Trp Phe Tyr Tyr Asp Ser Gln Asn Lys Ser Lys Asp Leu Arg Pro Tyr

85 90 95Arg Ile Glu Lys Glu Lys Gly Glu Asp Asp Ile Val Met Ile Cys Glu

100 105 110Phe Ser Arg Trp Thr Ile Gly Val Arg Ile Tyr Glu Ala Asp Arg Ile

115 120 125Leu Ser Lys Lys Trp Thr Glu Met Glu Gln Ser Ala Gly Leu Gly Gly

130 135 140Ser Ala Gly Asn Asn Lys Leu Val Ser Arg Thr Arg Tyr Phe Asp Gly145 150 155 160Arg Leu Val Gln Val Val Asp Ile Glu Lys Met Leu Ile Asp Val Phe

165 170 175Pro Trp Ile Glu Asp Glu Lys His Asn Asp Leu Glu Thr Leu Ser Lys

180 185190Ile His Ser Asn Gln Cys Val Leu Leu Ala Asp Asp Ser Pro Ser Val

195 200 205Leu Lys Thr Met Gln Met Ile Leu Asp Lys Leu Gly Val Lys His Ile

210 215 220Asp Phe Ile Asn Gly Lys Thr Leu Leu Glu His Leu Phe Asn Pro Thr225 230 235 240Thr Asp Val Ser Asn Ile Gly Leu Ile Ile Thr Asp Leu Glu Met Pro

245 250 255Glu Ala Ser Gly Phe Glu Val Ile Lys Gln Val Lys Asn Asn Pro Leu

260 265 270Thr Ser Lys Ile Pro Ile Val Val Asn Ser Ser Met Ser Gly Ser Ser

275 280 285Asn Glu Asp Met Ala Arg Ser Leu Lys Ala Asp Asp Phe Ile Ser Lys

290295300 Ser Asn Pro Lys Asp Ile Gln Arg Val Val Lys Gln Phe Leu Glu Leu 305310315320 Ala (2) SEQ ID NO:983 information

Sequence properties:

(A) length: 735 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...735

(xi) sequence representation: SEQ ID NO 983: ATGCAATTTC AAAAAACCTT ATCTTCCTTA TCTTTATTTT TATCTTTATC TTTATTCTTA 60TCTTTTAGTA TCGCTGAAGA AAATGGGGCG TATGCGAGCG TGGGTTTTGA ATATTCCATT 120AGTCATGCCG TTGAGCACAA TAATCCCTTT TTAAATCAAG AACGCATCCA AACGATTTCT 180AACGCTCAAA ACCAAATCTA TAAACTCAAT CAAATTGAAA ATGAAATCAC AAACATGCAA 240AACACCTTTA ACTACACCAA CAACGCTTTG AAAAACAATG CTAAATTAAC CCCCACTGAA 300ATGCAAGCCG AACAATACTA CCTCCAATCC ACCCTTCAAA ACATTGAAAA AATAGTCATG 360CTTAGCGGTG GCGTTGCGTC TAACCCTAAA CTAGTCCAAG CGTTAGAAAA AATGCAAGAA 420CCCATTACTA ACCCTTTAGA ATTGGTAGAA AACTTAAAAA ATTTAGAATT ACAATTCAGC 480CAATCTCAAA ACAGCATGCT TTCTTCTTTG TCTTCTCAGA TCGCTCAAAT TTCAAATTCT 540TTGAACGCGC TTGATCCCAG CTCTTATTCT AAAAACGTTT CAAGCATGTA TGGGGTAGGT 600TTGAGCGTAG GGTATAAGCA TTTCTTTACC AAGAAAAAAA ATCAAGGGTT TCGTTATTAC 660TTATTCTATG ACTATGGTTA CACTAATTTT GGTTTTGTGG GTAATGGCTT TGATGGTTTA 720GGCAAAATGA ATAAC 735(2) SEQ ID NO 984 information

Sequence properties:

(A) length: 1899 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1899

(xi) sequence representation: SEQ ID NO 984: ATGAAACCAA CGAACGAACC TAAAAAACCT TTTTTTCAAA GTCCCATTGT TCTTGCGGTT 60CTTGGAGGGA TTTTACTCAT TTTTTTCCTA CGCTCTTTCA ATTCTGATGG CAGTTTTTCG 120GACAATTTCT TAGCTTCTAG CACTAAAAAT GTGAGCTACCATGAAATCAA ACAGCTCATC 180AGCAATAATG AAGTGGAAAA TGTGAGTATC GGTCAAACTT TGATCAAAGC CAGCCATAAA 240GAGGGCAATA ATCGTGTGAT TTATATCGCT AAACGAGTGC CTGATCTAAC CTTAGTGCCT 300TTGTTAGACG AGAAAAAAAT CAATTATTCT GGTTTTAGCG AATCTAACTT TTTTACCGAC 360ATGTTAGGGT GGCTCATGCC TATTTTAGTG ATTTTAGGGC TATGGATGTT TATGGCAAAC 420CGCATGCAAA AAAATATGGG TGGGGGTATT TTTGGCATGG GGAGCGCGAA AAAACTCATT 480AACGCTGAAA AACCCAATGT GCGTTTTAAT GACATGGCGG GCAATGAAGA AGCCAAAGAA 540GAAGTAGTAG AAATCGTGGA TTTCTTAAAA TACCCCGAAC GATACGCCAA TTTAGGGGCT 600AAAATCCCTA AAGGTGTGCT GTTAGTAGGG CCTCCAGGAA CCGGTAAAAC CCTTTTAGCA 660AAGGCGGTGG CTGGCGAAGC GCATGTGCCG TTTTTCTCTA TGGGAGGGAG CAGTTTCATT 720GAAATGTTTG TGGGCTTAGG GGCAAGCAGG GTTAGGGATT TGTTTGAAAC CGCTAAAAAA 780CAAGCCCCTA GCATCATTTT TATTGATGAA ATTGATGCCA TAGGCAAGAG CAGAGCGGCT 840GGAGGCATGA TAAGTGGGAA TGATGAGAGA GAGCAAACCC TAAACCAGCT CTTAGCCGAA 900 63900 900ATGGATGGTT TTGGGAGCGA AAACGCACCT GTCATTGTTT TAGCCGCAAC GAACCGCCCT 960GAAATCTTGG ATCCGGCTTT AATGCGTCCA GGGCGCTTTG ACAGGCAGGT TTTAGTGGAT 1020AAGCCTGATT TTAATGGCAG GGTGGAAATC TTAAAAGTGC ATATTAAAGG CGTGAAACTC 1080GCTAATGATG TGAATTTGCA AGAAGTCGCC AAACTCACCG CAGGGCTTGC AGGGGCGGAT 1140TTGGCGAATA TCATCAATGA AGCCGCGCTT TTAGCGGGAC GAAACAACCA AAAAGAAGTC 1200AAACAACAGC ATTTAAAAGA AGCGGTTGAA AGAGGGATTG CTGGGCTAGA AAAGAAAAGC 1260AGGCGTATCA GTCCTAAAGA AAAGAAAATC GTCGCCTACC ATGAAAGCGG GCATGCCGTG 1320ATTTCTGAAA TGACTAAAGG GAGCACTAGG GTGAATAAAG TCTCTATCAT TCCAAGGGGC 1380ATGGCGGCTT TAGGCTACAC CCTTAACACG CCTGAAGAAA ACAAATACTT GATGCAAAAA 1440CACGAACTCA TCGCTGAAAT TGATGTGCTT TTAGGCGGGA GGGCGGCTGA AGAAGTCTTT 1500TTAGAAGAAA TTTCTACCGG TGCGAGCAAC GATTTAGAAA GAGCGACTGA TATTATTAAA 1560GGCATGGTGA GTTACTACGG CATGAGCAGT GTCAGCGGGC TTATGGTGTT AGAAAAGCAA 1620CGGAACGCCT TTTTAGGAGG CGGTTATGGG AGCAGTAGGG AATTTACCGA AAAAACCGCA 1680GAAGAAATGG ATCTTTTCAT TAAAAACCTA CTAGAAGAGC GCTATCAGCA TGTCAAACAA 1740ACCTTAAGCG ACTATAGAGA GGCGATTGAA ATCATGGTCA AAGAATTGTT TGACAAAGAA 1800GTCATTACAG GCGAAAGGGT GCGTGAAATC ATCAGCGAAT ACGAAGCCGC CAACAATTTA 1860GAAAGCCGTT TGATCCCTTT AGAAGAGCAA GCGAGTTAA 1899(2) SEQ ID NO:985information

Sequence properties:

(A) length: 3867 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...3867

(xi) sequence representation: SEQ ID NO 985: ATGGAAATAC AACAAACACA CCGCAAAATC AATCGCCCTT TAGTTTCTCT CGTTTTAGCA 60GGAGCGTTGA TTAGCGCCAT ACCGCAAGAG AGTCATGCCG CCTTTTTCAC GACCGTGATC 120ATTCCAGCCA TTGTTGGGGG TATCGCCACA GGCACTGCTG TAGGAACGGT CTCAGGGCTT l80CTTAGTTGGG GACTCAAACA AGCCGAAGAA GCGAATAAAA CCCCAGATAA ACCCGATAAA 240GTTTGGCGCA TTCAAGCAGG AAAAGGCTTT AATGAATTTC CTAACAAGGA ATACGACTTA 300TACAAATCCC TTTTATCCAG TAAGATTGAT GGAGGTTGGG ACTGGGGGAA CGCCGCTAGG 360CATTATTGGG TCAAAGGCGG GCAATGGAAC AAGCTTGAAG TGGATATGAA AGACGCTGTA 420GGGACTTATA AACTATCAGG GCTTAGAAAC TTTACTGGTG GGGATTTAGA CGTGAATATG 480CAAAAAGCCA CTTTGCGTTT GGGCCAATTC AATGGCAATT CTTTCACAAG CTATAAGGAT 540AGCGCTGATC GCACCACGAG AGTGAATTTC AACGCTAAAA ATATTTCAAT TGATAATTTT 600GTAGAAATCA ATAATCGTGT GGGTTCTGGA GCCGGGAGAA AAGCCAGCTC TACGGTTTTG 660ACTTTGCAAG CTTCAGAAGG GATCACTAGC AGTAAAAATG CGGAAATTTC TCTTTATGAT 720GGCGCCACGC TCAATTTGGC TTCAAACAGC GTTAAATTAA ATGGTAATGT GTGGATGGGC 780CGTTTGCAAT ACGTGGGAGC GTATTTAGCC CCTTCATACA GCACGATCAA CACTTCAAAA 840GTTCAAGGGG AAGTGGATTT TAACCATCTC ACTGTGGGGG ATCAAAACGC CGCTCAAGCG 900GGCATTATCG CTAGCAATAA GACTCATATT GGCACACTGGATTTGTGGCA AAGCGCCGGG 960TTAAATATCA TTGCCCCTCC AGAAGGTGGC TACAAGGATA AACCTAATAG TACCACTTCT 1020CAAAGTGGCA CTAAAAACGA CAAGAAAGAG ATCAGTCAAA ATAACAATAG CAACACAGAG 1080GTCATTAACC CACCCAATAA CACGCAAAAA ACAGAAACTG AACCCACGCA AGTCATTGAT 1140GGGCCTTTTG CTGGCGGCAA AGACACGGTT GTCAATATTT TCCACTTAAA CACTAAAGCC 1200GATGGCACGA TTAAAGTGGG AGGGTTTAAA GCTTCTCTTA CCACGAATGC GGCTCATTTG 1260AATATCGGCA AAGGCGGTGT CAATCTGTCC AATCAAGCGA GCGGGCGCAC CCTTTTAGTG 1320GAAAATCTAA CCGGGAATAT CACCGTTGAT GGGCCTTTAA GAGTGAATAA TCAAGTGGGT 1380GGCTATGCTT TGGCAGGATC AAGCGCGAAT TTTGAGTTTA AGGCTGGTGT GGATACTAAA 1440AACGGCACAG CCACTTTCAA TAACGATATT AGTTTGGGAA GATTTGTGAA TTTAAAGGTG 1500GATGCTCATA CAGCTAATTT TAAAGGTATT GATACGGGTA ATGGTGGTTT CAACACCTTA 1560GATTTTAGTG GTGTTACAGA CAAAGTCAAT ATCAACAAGC TCATCACAGC TTCCACTAAT 1620GTGGCCGTTA AAAACTTCAA CATTAATGAA TTGATTGTTA AAACCAATGG GATAAGTGTG 1680GGGGAATACA CTCATTTTAG CGAAGATATA GGCAGTCAAT CGCGTATCAA TACCGTGCGT 1740TTGGAAACTG GCACTAGGTC AATCTTTTCT GGGGGTGTCA AATTTAAAAG CGGTGAAAAA 1800CTAGTTATCA ATGATTTTTA CTATAGCCCT TGGAATTATT TTGACGCTAG GAATGTTAAA 1860AATGTTGAAA TCACCAGAAA ATTCGCTTCT TCAACCCCAG AAAACCCTTG GGGCACATCA 1920AAGCTCATGT TTAATAATCT AACCTTGGGT CAAAATGCGG TCATGGACTA TAGTCAATTT 1980TCAAATTTAA CCATTCAGGG GGATTTTATC AACAATCAAG GCACTATCAA CTATCTGGTC 2040CGAGGCGGGA AAGTGGCAAC CTTAAATGTA GGCAATGCAG CAGCTATGAT GTTTAATAAT 2100GATATAGACA GCGCGACCGG ATTTTACAAA CCGCTCATCA AGATTAACAG CGCTCAAGAT 2160CTCATTAAAA ATACAGAGCA TGTTTTATTG AAAGCGAAAA TCATTGGTTA TGGTAATGTT 2220TCTACAGGTA CCAATGGCAT TAGTAATGTT AATCTAGAAG AGCAATTCAA AGAGCGCCTA 2280GCCCTTTATA ACAATAATAA CCGCATGGAT ACTTGTGTGG TGCGAAATAC TGATGACATT 2340AAAGCATGCG GTATGGCTAT CGGCAATCAA AGCATGGTGA ACAACCCTGA CAATTACAAG 00 2400TATCTTATCG GTAAGGCATG GAGAAATATA GGCATCAGTA AAACGGCTAA CGGCTCTAAA 2460 2520TTACCCACAA ACACCACTAA TAATGCGCAT TCTGCTAACT ACGCTCTCGT GAAGAACGCT 2580CCTTTCGCTC ACAGCGCCAC TCCTAATTTA GTCGCTATCA ATCAGCATGA TTTTGGCACT 2640ATTGAGAGCG TGTTTGAATT GGCTAACCGC TCTAAAGATA TTGACACGCT CTATACTCAT 2700TCAGGCGCGC AAGGCAGGGA TCTCTTGCAA ACTTTATTGA TTGATAGCCATGATGCGGGT 2760TATGCCAGAC AAATGATTGA TAACACAAGC ACCGGTGAAA TCACCAAGCA ATTGAATGCG 2820GCCACTGACG CTTTAAACAA CGTAGCCAGT TTAGAGCATA AACAAAGCGG CTTACAAACC 2880TTGAGCTTGA GTAATGCGAT GATTTTAAAT TCTCGTTTAG TCAATCTCTC TAGGAAGCAC 2940ACCAACCATA TTAACTCGTT CGCTCAACGC TTACAAGCTT TAAAAGGCCA AGAATTCGCT TCTTTAGAGA GCGCGGCAGA AGTGTTGTAT CAATTTGCCC CTAAATATGA AAAACCTACC 3060AATGTTTGGG CTAACGCTAT TGGGGGAGCG AGCTTGAATA GCGGCTCTAA CGCTTCATTG 3120TATGGCACAA GCGCCGGCGT AGACGCTTTC CTTAACGGGA ATGTGGAAGC CATTGTGGGC 3180GGTTTTGGAA GCTATGGTTA TAGCTCCTTT AGCAATCAAG CGAACTCTCT TAACTCTGGG 3240GCCAATAACG CTAATTTTGG CGTGTATAGC CGTTTTTTTG CCAACCAGCA TGAATTTGAC 3300TTTGAAGCTC AAGGGGCGCT AGGGAGCGAT CAATCAAGCT TGAATTTCAA AAGCACTCTA 3360TTACAAGATT TGAATCAAAG CTATAATTAC TTAGCCTATA GCGCCACAGC AAGAGCGAGT 3420TATGGTTATG ACTTCGCGTT TTTTAGGAAC GCTTTAGTGT TAAAACCAAG CGTGGGCGTG 3480AGCTATAACC ATTTAGGTTC AACCAACTTT AAAAGCAATA GCCAATCACA AGTGGCTTTA AAAAATGGCG CGAGCAGTCA GCATTTATTC AACGCTAACG CTAACGTGGA AGCGCGTTAT 3600 3660TTTGGATCGA ATGATGTGGC GTCTTTAAAC ACCTTTAAAA TCAATGCCGC TCGCAGTCCT 3720TTAAGCACCT ATGCAAGAGC GATGATGGGT GGGGAATTGC AATTGGCTAA AGAAGTGTTT 3780TTGAATTTGG GCGTGGTTTA TTTGCACAAT TTGATTTCCA ACGCAAGCCA TTTCGCTTCC 3840AATTTAGGAA TGAGGTATAG TTTCTAA 3867(2) SEQ ID NO:986 information.

Sequence properties:

(A) length: 4455 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...4455

(xi) sequence representation: 986: GGGGCGGTCT CTTTACGAGG GCAGTTTAAT TTAAGCAATA ATTCTTCTTT AGATTTTCAA 60GGCTCTAGCG CTATCACCTC TAACACGGCG TTTAATTTCT ATGATAACGC TTTTTCTCAA 120AGCCCCATCA CTTTCCATCA AGCCCTTGAC ATTAAAGTGC CCTTGAGTTT GGGAGGCAAC 180CTCTTAAACC CTAACAACAG TAGCGTGCTG AATTTAAAAA ACAGCCAGCT TGTTTTTAGC 240GATCAAGGGA GCTTGAATAT CGCTAACATT GATTTACTAA GCGATCTGAA TGGTAATAAA 300AATCGTGTGT ATAACATCAT TCAAGCGGAC ATGAATGGTA ATTGGTATGA GCGTATCAAC 360TTCTTTGGCA TGCGCATTAA TGATGGGATT TATGACGCTA AAAACCAAAC TTATAGTTTC 420ACTAACCCTC TCAATAACGC CCTAAAAATC ACCGAGAGCT TTAAAAATAA CCAACTGAGC 480GTTACGCTCT CTCAAATCCC GGGCATTAAA AACACGCTCT ATAACATTGG CTCTGAAATC 540TTTAACTACC AAAAGGTTTA TAACAACGCT AATGGCGTGT ATTCTTATAG CGATGACGCA 600CAAGGCGTGT TTTATCTCAC GAGCAGCGTG AAAGGCTATT ACAACCCCAA CCAATCCTAT 660CAAGCCAGCG GCAGCAATAA CACCACGAAA AATAACAATC TAACCTCTGA ATCTTCTGTC 720ATTTCGCAAA CCTATAACGC GCAAGGCAAC CCTATCAGCG CGTTACACGT CTATAACAAG 780GGCTATAATT TCAGTAATAT CAAAGCGTTA GGGCAAATGG CGCTCAAACT CTACCCTGAA 840ATCAAAAAGA TATTAGGGAA TGATTTTTCG CTTTCAAGTT TGAGCAATTT AAAAGGCGAT 900GCGCTAAACC AGCTTACCAA GCTCATCACG CCTAGCGATT GGAAAAACAT TAACGAGTTG 960ATTGATAACG CAAACAATTC GGTCGTGCAA AATTTCAATA ACGGCACTTT GATTATAGGA 1020GCGACTAAAA TAGGGCAAAC AGACACCAAT AGTGCGGTGG TTTTTGGGGG CTTGGGCTAT 1080CAAAAGCCTT GCGATTACAC TGATATTGTG TGCCAAAAAT TTAGAGGCAC TTATTTGGGG 1140CAGCTTTTGG AGTCCATCTC GGCTGATTTG GGCTATATTG ACACGACTTT TAACGCTAAA 1200GAAATTTATC TTACCGGCAC TTTAGGGAGC GGGAACGCAT GGGGGACTGG GGGGAGTGCG 1260AGCGTAACTT TTAACAGCCA AACTTCGCTC ATTCTCAACC AAGCGAATAT CGTAAGCTCG 1320CAAACCGATG GGATTTTTAG CATGCTGGGT CAAGAGGGCA TCAATAAGGT TTTCAATCAA 1380 581440 TTAGGGAATT TGATAGTAAA TACGCTAGGG AGTGATAGCG TGATTGGGGG GTATTTAACG 1500CCTGAGCAAA AAAATCAAAC CCTAAGCCAG CTTTTGGGGC AGAATAATTT TGATAACCTC 1560ATGAACGATA GCGGTTTGAA CACGGCGATT AAGGATTTGA TCAGACAAAA ATTAGGCTTT 1620TGGACCGGGC TAGTGGGGGG ATTAGCCGGA CTGGGGGGCA TTGATTTGCA AAACCCTGAA 1680AAGCTTATAG GCAGCATGTC CATCAATGAT TTATTGAGTA AAAAGGGGTT GTTCAATCAG 1740ATCACCGGCT TTATTTCCGC TAACGATATA GGGCAAGTCA TAAGCGTGAT GCTGCAAGAT 1800ATTGTCAAGC CGAGCGACGC TTTAAAAAAC GATGTAGCCG CTTTGGGCAA GCAAATGATT 1860GGCGAATTTT TAGGCCAAGA CACGCTCAAT TCTTTAGAAA GCTTGCTGCA AAACCAGCAG ATTAAAAGCG TTTTAGACAA AGTCTTAGCG GCTAAAGGAT TAGGGTCTAT TTATGAACAA 1980GGTTTGGGGG ATTTGATCCC TAATCTTGGT AAAAAGGGGA TTTTCGCTCC CTATGGCTTG 2040AGTCAAGTGT GGCAAAAAGG GGATTTTAGT TTCAACGCGC AAGGCAATGT TTTTGTGCAA 2100AATTCCACTT TCTCTAACGC TAATGGAGGC ACGCTCAGTT TTAACGCAGG AAATTCGCTC 2160ATTTTTGCCG GAAACAACCA CATCGCTTTC ACTAACCATT CTGGAACGCT CAATTTGTTG 2220TCTAATCAAG TTTCTAACAT TAACGTCACC ATGCTTAACG CTAGCAACGG CCTTAAGATT 2280AACGCCACTA ATAACAATGT TTCCGTGTCT CAAGGCAATC TGTTTATCAA CGCTAGCTGC 2340 2400AACGCTTCTT CTAGTAATGC GTCAAACAAC GCGCCAATCG CCTTAAATAA TAACGATGAA 2460AGCTTGGTGG TTACGGCGAA TGGTTTCAAT TTTTCAGGCA ATATTTACGC TAACGGGGTG 2520GTTGATTTTT CAAAAATTAA AGGCTCTGCA AACGTTAAAA ACCTGTATCT TTACAATAAC 2580GCTCAATTCC AAGCCAACAA CCTCACGATT TCCAACCAAG CGGTATTAGA GAAAAACGCT 2640AGCTTTGTAA CGAATAACTT AAACATTCAA GGAGCGTTTA ACAACAACGC CACGCAAAAA 2700ATAGAGGTGC TTCAAAATTT AGTGATCGCT TCAAACGCTT CTTTAAGCAC CGGGATTTAT 2760GGGTTAGAAG TAGGGGGGGC ATTGAATAAT TTGGGAGCGA TCCATTTTAA TTTAGAAAAT 2820TCTCAAACGC CTGTAAATCC GCTCATTCAA GTAGGGGGGA TCATTAATCT CAACACCACC 2880CAAACGCCTT TTATGAATGT CAGCGTGGCT AATGGCGGAA CTTACACTTT ATTAAAAAGC 2940AGCCGTTATA TTGATTACAA TATCAACCCT AACAGCTTGC AATCGTATTT GAAGCTCTAT 3000ACCTTAATCA ATATCAACGG AAACCACATA GAGGAAAAAA ACGGCGTATT GACTTATTTG 3060GGCCAACGGG TTTTATTACA AGATAAGGGG TTATTATTGA GTGTAGCACT ACCTAACTCA 3120AACAACGCCT CTCAAAACAA CATTTTAAGC CTTTCTGTCC TTCACAACCA GATTAAAATG 3180TCTTATGGTA ATAAAGTGAT GGACTTTACC CCTCCCACCT TACAGGATTA CATTGTGGGC 3240ATTCAAGGAC AAAGCGCACT CAATCAAATT GAAGCTGTTG GGGGGAATAA CGCTATCAAG 3300TGGCTTTCAA CATTGATGAT GGAGACTAAA GAAAACCCGC TTTTTGCGCC GATTTATTTA 3360GAAAACCACT CTTTAAATGA AATCTTAGGC GTAACAAAAG ATCTTCAAAA CACCGCAAGC 3420TTGATTTCTA ACCCTAATTT TAGAAATAAC GCTACCAGCC TTTTAGAAAT GGCGAGTTAC 3480ACCCAACAAA CCAGCCGTTT GACAAAACTC TCTGATTTTA GGGCTAGAGA GGGAGAGTCC 3540AATTTTTCAG AGCGCTTGTT AGAGCTTAAA AACAAGCGTT TTAGCGATCC TAACCCTAGT 3600GAGGTTTTTG TCAAATACTC TCAACTCAGC AAACACCCCA ATAACCTTTG GATTCAAGGG 3660GTGGGAGGAG CGAGCTTTAT TTCTGGGGGC AATGGCACGC TTTATGGCTT GAATGTGGGC 3720TATGACCGAT TGGTTAAAAG CGTGATCCTT GGGGGTTATG TGGCTTATGG CTATAGCGGT 3780TTTAACGGGA ACATCATGCA TTCTTTGGCT AATAATGTGG ATGTGGGGAT GTATGCGAGG 3840GCTTTTTTGA AAAGAAACGA ATTCACTTTG AGCGCGAATG AAACTTATGG AGGCAATGCG 3900AGTCATATCA ATTCTTCTAA TTCCTTGCTC TCTGTGTTGA ACCAACGCTA CAACTACAAC 3960ACCTGGACAA CGAGCGTGAA TGGGAATTAC GGCTATGATT TCATGTTCAA ACAAAAAAGC 4020GTGGTGCTAA AACCTCAAGT GGGCTTGAGC TATCATTTCA TAGGCTTGAG CGGGATGAAA 4080GGTAAAATGC AAAATCCAGC TTACCAACAA TTCGTCATGC ATTCAAACCC TTCTAACGAA 4140TCGGTTTTAA CGCTCAACAT GGGGTTAGAG AGCCGTAAAT ATTTTGGTAA AAATTCCTAT 4200TATTTTGTAA CGGCGAGGTT GGGTAGGGAT CTTTTGATCA AAGCTAAAGG CGACAATGTG 4260GTGCGTTTTG TGGGTGAAAA CACTTTATTG TACCGCAAGG GGGAAATTTT TAACACTTTT 4320GCGAGCGTGA TCACAGGAGG CGAAATGCAT TTGTGGCGTT TGATGTATGT GAATGCGGGG 4380GTGGGGCTTA AAATGGGCTT GCAATACCAA GATCTTAATA TCACTGGGAA TGTGGGCATG 4440CGAGTGGCGT TTTAG 4455(2) SEQ ID NO:987 information

Sequence properties:

(A) length: 903 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...903

(xi) sequence representation: SEQ ID NO 987: ATGAGAAAAA CGATTTCAGC GTTGTTTTTA TCAGCGTGTA TAGGGTTATC GTCTGTTCAT 60GCGAGTAACG CTTTGATTTT ACAAACAGAT TTTAGCCTAA AAGATGGGGC CGTCTCGGCG 120ATGAAAGGCG TCGCTTTCAG CGTTGATTCT AATCTTAAAA TCTTTGATTT AACGCACGAA 180ATCCCCCCGT ATAACATTTG GGAAGGCGCT TACCGCTTGT ATCAGACCGC TAGTTATTGG 240CCAAAAGGCT CGGTATTTGT GAGCGTAGTG GATCCGGGCG TAGGCACTAA TCGTAAATCG 300GTGGTATTGA AAACTAAAAA CGGCCAGTAT TTCGTCTCTC CAGATAACGG CACGCTGACT 360TTGGTAGCGC AAACTTTGGG GATTGATAGC GTGCGTGAAA TTGATGAAAA AGCCAACCGC 420TTGAAAGGTT CTGAAAAATC CTATACTTTC CATGGCCGTG ATGTGTATGC TTACACTGGG 480GCGCGCTTGG CTTCTGGGGC GATCACATTC GAGCAGGTCG GGCCAGAGCT TCCTATAAAA 540GTTGTTGAAA TTCCTTACCA AAAAGCGAAA GCCACAAAAG GGGGAGTGAA AGGCAATATC 600CCGATTTTGG ATATTCAATA TGGCAATGTT TGGAGCAATA TCAGCGATAA ACTGCTCAAT 660CAAGCAGGGA TCAAACGAAA CGATACAGTG TGTGTAACTA TTTTTAAAAA TTCCAAGAAA 720CAATACGAAG GGAAAATGCC GTATGTCGCG AGCTTTGGCG ATGTGCCAGA AGGCCAGCCG 780TTGGTCTATT TAAACAGCTT GTTGAATGTT TCCGTGGCGT TGAATATGGA TAATTTCGCG 840CAAAAACATC AAATTAAATC TGGTGCTGAC TGGAATATTG ATATAAAGAA GTGCGCTAAA 900TAA 903(2) SEQ ID NO 988 information

Sequence properties:

(A) length: 1581 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1581

(xi) sequence representation: SEQ ID NO 988: ATGAAACTTT TTAACCCTCG TTTAATCGTT TTTATATTCG CGCTTCTTTT AGGGGTAGGG 60TTTTCTGTGC CTTCTTTGCT AGAAACTAAA GGCCCTAAAA TCACTTTAGG TTTGGATTTA 120AGGGGGGGGT TGAACATGCT TTTAGGGGTG CAAACCGATG AGGCTTTAAA AAACAAGTAT 180TTAAGCCTAG CGTCTGCTTT AGAATACAAC GCTAAAAAGC AAAATATCTT GCTTAAAGAC 240ATTAAATCCA GTTTAGAGGG GATCAGTTTT GAGCTTTTAG ATGAAGATGA GGCGAAAAAA 300TTAGACGCGC TTTTATTGGA ATTGCAAGGT CATAGCCAGT TTGAAATCAA AAAAGAAGCG 360GAGTTTTATA GCGTGAAACT CACCCCTTTA GAGCAAGAGG AATTGCGTAA AAACACGATC 420TTGCAAGTGA TAGGGATCAT TCGTAACCGC TTGGATCAAT TTGGTTTGGC AGAGCCTGTA 480GTCATTCAGC AAGGCCGAGA AGAAATTTCG GTGCAATTGC CCGGCATTAA GACTTTAGAA 540GAAGAGCGGC GCGCTAAAGA CTTGATTTCT AAATCCGCTC ATTTGCAGAT GATGGCAGTG 600GATGAAGAAC ACAATAAAGA TGCGATGAAT ATGACGGATT TAGAGGCTCA AAAATTAGGC 660AGCGTGTTGT TGTCTGATGC GGAAATGGGG GGTAAAATCT TACTCAAAGC GATCCCTATT 720TTAGATGGCG AAATGCTTAC AGATGCGAAA GTGGTGTATG ATCAAAATAA CCAGCCGGTG 780GTGAGCTTCA CGCTAGATGC GCAAGGGGCT AAGATTTTTG GGGATTTTTC AGGCGCGAAT 840GTGGGCAAAC GCATGGCGAT CGTTTTAGAC AATAAGGTCT ATTCAGCCCC GGTGATTAGG 900 63900 900GAACGCATTG GTGGGGGGAG CGGGCAGATT AACGGGAATT TTAGCGTGGC TCAAGCGAGC 960GATTTAGCGA TCGCTTTAAG GAGTGGGGCG ATGAACGCGC CCATTCAGGT TTTAGAAAAA 1020AGGATTGTAG GTCCGAGTTT AGGGAAAGAC AGCATTAAAA CTTCCATTAT CGCTCTAGTT 1080GGAGGCTTTA TTTTAGTGAT GGGCTTTATG GCACTTTATT ACTCCATGGC TGGGGTGATC 1140GCTTGCATGG CGTTAGTGGT CAATCTTTTT TTGATCGTGG CGGTCATGGC GATTTTTGGA 1200GCGACGCTGA CTTTACCGGG AATGGCAGGG ATTGTTTTAA CCGTGGGGAT TGCCGTGGAT 1260GCTAATATCA TTATCAACGA ACGCATTAGA GAAGTTTTAA GAGAAGGAGA GGGTGTTGTT 1320AAGGCGATCC ATTTAGGCTA TATCAATGCG AGCCGGGCGA TTTTTGACTC CAATATCACT 1380TCCTTGATCG CTTCGGTGTT GCTATACGCT TATGGCACAG GAGCGATTAA AGGCTTTGCC 1440CTCACCACAG GCATTGGGAT TTTAGCCTCT ATCATCACCG CTATTATAGG CACGCAAGGG 1500ATTTATCAAG CCCTTTTACC TAAATTAGCC CAAACGAAAA GCCTTTACTT TTGGTTTGGC 1560GTGAAAAATA AAAGAGCTTA G1581 (2) information of SEQ ID NO:989

Sequence properties:

(A) length: 2382 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(iv) original source:

(A) an organism: helicobacter pylori

(iv) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2382

(xi) sequence representation: SEQ ID NO 989: ATAATGAATG GTTATTTGAG GGTAAAAACC CCGTATTTTT TAGCGTCGGT CGTTTTGACT 60TTTTGGACTT TTAATTCTTT TATGAGCGCG AAAGATAAGC ACCATTTTTT AAAAAAAGTT 120ACAACCACCG AGCAAAAATT CAGTTCTAGT GCCCCAATTT CATGGCAAAG CGAAGAGGTG 180CGTAATTCCA CAAGCTCTCG CACGGTGATT TCCAACAAAG AACTCAAAAA AACGGGGAAT 240TTGAATATTG AAAACGCCTT GCAAAATGTG CCAGGGATTC AAATCAGAGA CGCTACAGGC 300ACGGGCGTGC TGCCTAAAAT TTCGGTGCGC GGTTTTGGTG GGGGCGGTAA CGGGCATAGC 360AACACCAACA TGATTTTAGT CAATGGTATC CCCATTTATG GCGCGCCGTA TTCCAATATT 420GAACTGGCGA TTTTCCCTGT AACTTTCCAG TCAGTGGATA GGATTGATGT GATTAAGGGG 480GGAACGAGCG TCCAATACGG CCCTAACACT TTTGGAGGCG TGGTGAATGT CATCACTAAA 540GAAATCCCCA AAGAGTGGGA AAATCAAGCG GCTGAAAGGA TCACTTTTTG GGGGCGCTCC 600TCTAATGGGA ATTTTGTCGA TCCCAAAGAA AAAGGCAAGC CCTTAGCCCA AACTTTAGGA 660AACCAAATGC TGTTTAACAC TTATGGGCGA ACGGCTGGGA TGTTGGGTAA ATATATAGGC 720ATTAGCGCTC AAGGCAATTG GATTAATGGG CAAGGTTTCA GGCAAAATAG CCCTACAAAG 780GTGCAAAACT ACTTGTTGGA TGCGATTTAT AAGATCAATG CGACCAATAC TTTTAAAGCT 840TATTACCAGT ATTATCAATA CAACTCTTAC CATCCAGGCA CTTTGAGCGC GCAAGATTAC 900 63900 900GCCTATAACC GCTTCATCAA TGAGCGCCCT GACAATCAAG ATGGAGGGCG AGCCAAGCGC 960TTTGGGATCG TGTATCAAAA CTACTTTGGC GATCCGGATA GGAAAGTGGG GGGCGATTTT 1020AAATTCACTT ATTTCACGCA TGACATGAGT AGGGATTTTG GGTTTTCCAA CCAATACCAA 1080AGCGTGTATA TGAGCGGTCA AAATAAGATT TTACCCTTTA AAGGCAAGGG AGAAATCAGC 1140GCAAAAAACC CTAATTGCGG TCTGTATTCT TATAGCGACA CGAATAGCCC TTGCTGGCAA 1200TTTTTTGACA ATATCCGCCG ATCCGTGGTG AATGCCTTTG AGCCAAAACT CAATCTTATC 1260GTCAATACTG GTAAAGTCAA ACAAACTTTT AACATGGGAA TGCGCTTTTT AACTGAAGAT 1320TTATACCGCC GATCCACCAC CAGGAAAAAC CCTAGCATGC CTAATAATGG GAGTGGGTTT 1380GATGCAGGAA CTTCACTCAA TAATTTCAAC AATTATACCG CTGTGTATGC CAGCGATGAA 1440ATCAATTTCA ATAACGGCAT GCTAACGATC ACGCCGGGCT TGAGATACAC TTTTTTAAAT 1500TACGAAAAAA AAGACGCTCC TCCCTTTAAG GTGGGTCAAA CCCCAAAAAC CACGAAAGAG 1560CGTTATAACC AATGGAATCC GGCAGTCAAT GTCGGCTATA AACCCATTAA AGAATTATTG 1620TTTTATTTCA ATTACCAAAG AAGCTACATT CCGCCCCAAT TCAGCAATAT CGGTAATTTT 1680GTAGGCACAA GCACGGATTA TTTTCAAATC TTTAATGTCA TGGAAGGCGG CTCAAGATAT 1740TATTTTAACC ATCAAGTGAG TTTTAACGCG AACTATTTTG TGATTTTTGC GAATCATTAT 1800TTTACCGGGC GCTATGGGGA CAACAGAGAG CCGGTCAATG CGAGATCGCA AGGCGTGGAG 1860CTGGAACTCT ACTACACGCC TATTAGGGGG CTTAATTTCC ATGCGGCTTA CACTTTTATA 1920GACGCTAATA TCACAAGCCA CACGATGGTT ACTAACCCTG CTAATCCTAA AGGGCCTAAA 1980AAAGATATTT TTGGCAAAAA GCTCCCTTTT GTCAGCCCGC ACCAATTCAT TTTAGACGCG 2040AGTTACACTT ACGCTAAAAC CACGATTGGG TTAAGCTCTT TCTTTTATAG CCGCGCTTAT 2100AGCGATGTGT TAAACACCGT GCCTTTTACA GAATACGCGC CCACGATTAA AAATGGGGCT 2160ATCGTTACCA AAACAGCGGG CATGACGCCG TACTATTGGG TGTGGAATTT GCAAATTTCT 2220ACCACTTTGT GGGAACGCAA AAATCAAAGC GTGAATGCGA GCTTGCAAAT CAATAACATT 2280TTTAACATGA AATATTGGTT TAGCGGGATA GGCACTAGCC CTAACGGGAA AGAAGCTGCG 2340CCTCCCAGGA GCATCACAGC GTATGTGAGT TATAATTTTT AA 2382(2) SEQ ID NO 990 information

Sequence properties:

(A) length: 1002 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1002

(xi) sequence representation: SEQ ID NO 990: ATGCTAATCG CTCGCTTTAA AAAAGCTTTA ATTTCCTATT CTTTAGGGGT TCTTCTTGTT 60TCATCGTTAT TAGGCGTGGC TAACGCTTCT AATCAAGAGA TCCAAGTCAA GGATTATTTT 120GGGGAGCAAA CCATAAAGCT TCCTGTTTCT AAAATAATCT ACTTGGGCAG CTTTGCAGAA 180GTGCCTGCCA TGTTCAATAC TTGGGATAGG GTCGTGGGCA TTTCGGATTA CGCTTTTAAA 240TCTGATATTG TTAAAGCCAC TCTCAAAGAT CCTGAACGCA TTAAACCCAT GAGCAGTGAT 300CATGTGGCGG CGTTGAATGT GGAATTATTA AAAAAGCTTA GCCCTGATCT TGTGGTAACC 360TTTGTGGGTA ACCCTAAAGC GGTAGAGCAT GCGAAAAAAT TTGGGATTTC ATTCCTTTCT 420TTCCAAGAAA AAACCATTGT AGAGGTCATG GAAGATATTG ACGCTCAAGC TAAGGCCTTA 480GAAGTTGACG CTTCTAAAAA ATTGGCTAAA ATGCAAGAAA CTTTGGATTT TATCAAAGAG 540CGTTTGAAAA ATGTCAAAAA GAAAAAGGGG GTGGAGCTTT TCCATAAAGC CAATAAAATC 600AGCGGCCATC AAGCCCTTGA TTCAGATATT TTAGAAAAAG GGGGCATAGA CAATTTTGGC 660TTGAAATACG TCAAGTTTGG GCGCGCTGAC ATTAGTGTGG AAAAAATCGT TAAAGAAAAC 720CCTGAGATTA TTTTTATTTG GTGGATAAGC CCGCTTAGCC CTGAAGACGT GTTGAACAAC 780CCTAAATTTT CCACTATCAA AGCCATTAAA AACAAGCAAG TCTATAAGCT CCCCACAATG 840GATATTGGCG GACCTAGAGC CCCACTCATT AGTCTTTTTA TCGCTTTAAA AGCCCACCCT 900GAAGCGTTTA AGGGCGTGGA TATTAATGCG ATAATCAAAG ATTACTATAA AGTGGTCTTT 960GATTTGAATG ACGCGGAAGT TGAACCCTTT TTGTGGCACT GA 1002(2) SEQ ID NO 991 information 991

Sequence properties:

(A) length: 1203 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1203

(xi) sequence representation: SEQ ID NO:991: ATGTATAAAT TAGGAATATT TTTATTAGCC ACCTTACTAT CAGCTAACAC GCAAAAAGTG 60AGCGATATTG CTAAAGACAT CCAACATAAA GAAACCCTTT TGAAAAAAAC CCATCAAGAA 120AAAAACCAAC TGAACAGTCG TTTGAGTTCT TTAGGCGAAG CGATCCGCTC TAAAGAGCTT 180CAAAAGGTTG AGATTGAACG CCAAATGGTC GCCTTAAAAA AGAGTCTTGA AAAAAATCGT 240AACGAAAGTT TGGTGCAAGA AAAAGTCCTA ACCAACTACC GCAAGTCTTT AGATCATTTG 300CAAAAACAAC GATCGTTTTT ACAAAAGAGA GTGTTTGATA CGCTTTTAGA GGATTTTCTT 360TTCTCACAAG CCCTAAAGGG GCAGAATTTA GCCTCTTCTA ATGATGTGAT TTTGCAAGTG 420GCGTTTGAAA ACTTGCACCA AAGCACCCTG TCTAAAATGT CGCAACTGAG CCAAGAAGAA 480AAGAAGCTCA ATGTGCAAGC TTTAGAAGTC AAAAGCAGCA TTCAAAAAAT CTCCTCTGTC 540ATAGATGAGC AAAAAACTCG TGAATCAACC TTAAAATCCT TGCAAACCGA ACAAAATAAG 600CTCATTTTGA GCATGCAAAA AGATTATGCG ATCTATAACC AACGGCTATC CCTTTTAGAA 660AAAGAACGCC AGAATTTAAA CGCTCTTTTA AAACGCTTGA ATATCATCAA ACAAAATAGG 720GAAAATGAAG AGAGGGTCAG TTTGAAAAAA TCTTCTCAAG CTTTAGAAGT CAAACAAGTG 780GCTAGCTCTT ATCAAAATAT CAACACCACG AGCTATAACG GGCCAAAAAC GATCGCTCCC 840TTGAACGATT ACGAAGTGGT GCAAAAATTT GGCCCCTATA TTGACCCGGT TTATAATTTA 900AAAATTTTTA GCGAGTCTAT CACGCTAGTG TCAAAAACCC CAAACGCTTT GGTGCGTAAT 960GTTTTAGACG GGAAAATCGT GTTCGCTAAA GAAATCAACA TGCTTAAAAA AGTCGTTATC 1020ATTGAGCATA AAAACGGGAT CCGCACGATT TATTCTCAAT TGGATAAAAT CGCCCCCACC 1080ATTAAAAGCG GCATGCGGAT CCAAAAAGGC TATGTTTTAG GACGCATTGA TCAACGCTTG 1140GGCTTTGAAG TTACCATGAG AGAAAAGCAC ATTAACCCCT TAGAACTCAT CGCGCGCAAT 1200TAA 1203(2) SEQ ID NO:992 of the user.

Sequence properties:

(A) length: 1650 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: microsfecture

(B) Position: 1...1650

(xi) sequence representation: SEQ ID NO 992: ATGGATAAAA ACAACAATAA TAATCTCCGC TTGATTTTAG CGATCGCTCT GTCTTTCTTG 60 TTTATCGCTC TTTATAGCTA TTTTTTCCAA GAACCAAACA AAACAACAAC CGAAACCACA 120AAGCAAGAAA CAACCAACAA CCACACAGCA ACAAGCCCCA CCGCGTCCAA TACCATCACC 180CAAGATTTTA GCGTTACCCA AACCATCCCT CAAGAGAGTT TGTTAAGCAC GATTTCTTTT 240GAACATGCCA AAATTGAAAT TGATTCTTTA GGGCGCATCA AACAGGTTTA TCTCAAAGAT 300 AAAAAGTATC TAACCCCTAA AGAAAAGGGC TTTTTAGAGC ATGTGAGCCA TCTTTTTAGC 360TCCAAAGAAA ACTCGCAACC CTCCCTAAAA GAGCTCCCCC TTTTAGCAGC CGATAAACTC 420AAGCCTTTAG AAGTGCGTTT TTTAGACCCC ACGCTCAATA ATAAAGCGTT CAACACCCCT 480TATAGCGCCT CAAAAACCAC CCTTGGGCCT AACGAACAGC TCGTTTTAAC CCAAGATTTA 540GGCACTCTTA GCATCATTAA AACCCTGACT TTTTATGATG ATTTGCATTA TGATTTAAAA 600ATCGCATTCA AATCGCCCAA TAACCTTATC CCTAGCTATG TGATCACCAA TGGTTACAGG 660CCGGTGGCTG ATTTAGACAG CTACACCTTT TCAGGCGTGC TTTTAGAAAA CACCGACAAA 720AAAATTGAAA AAATTGAAGA TAAAGACGCT AAAGAAATCA AACGCTTTTC TAACACCCTC 780TTTTTATCCA GCGTGGATAG GTATTTCACT ACTTTGCTTT TCACTAAAGA TCCTCAAGGT 840TTTGAAGCCT TAATTGATTC AGAAATAGGG ACTAAAAACC CCTTAGGGTT CATTTCCCTT 900AAAAACGAAG CGAATTTGCA TGGCTATATT GGCCCTAAAG ATTACCGCTC TTTGAAAGCG 960ATTTCACCCA TGCTCACTGA TGTGATAGAG TATGGCTTGA TCACTTTCTT TGCCAAAGGC 1020GTGTTTGTTT TACTGGATTA TTTGTATCAA TTTGTGGGCA ATTGGGGTTG GGCTATCATT 1080CTTTTAACGA TTATCGTGCG CATTATCCTC TACCCCTTAA GCTATAAGGG CATGGTGAGC 1140ATGCAAAAGC TCAAAGAATT AGCCCCTAAA ATGAAAGAAC TCCAAGAAAA ATACAAGGGC 1200GAACCCCAAA AGTTACAAGC CCACATGATG CAGCTTTACA AAAAACATGG GGCTAACCCG 1260CTAGGGGGTT GTTTGCCCTT AATCTTACAA ATCCCAGTAT TTTTTGCGAT TTATAGAGTG 1320CTTTATAACG CTGTGGAATT GAAAAGCTCA GAGTGGGTTT TATGGATCCA TGATTTATCC 1380ATCATGGATC CGTATTTCAT TTTACCGCTT CTTATGGGAG CGTCTATGTA TTGGCACCAG 1440AGCGTTACGC CAAACACCAT GACCGATCCC ATGCAAGCAA AGATTTTTAA ACTCTTGCCC 1500CTATTATTCA CGATCTTTCT AATCACTTTC CCTGCAGGGT TAGTCTTGTA TTGGACCACA 1560CACAACATCC TTTCGGTGTT GCAGCAACTC ATCATTAATA AAGTCTTAGA GAATAAAAAA 1620CGCGCGCACG CTCAAAACAT AAAGGAATAA 1650(2) SEQ ID NO 993 information

Sequence properties:

(A) length: 1440 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1440

(xi) sequence representation: SEQ ID NO 993: ATGAAAAAAT CCCTTTGTTT GTCTTTCTTT CTGACCTTCT CTAACCCTCT TCAAGCCCTT 60GTCATTGAGC TTTTAGAAGA GATTAAAACT TCGCCGCATA AAGGCACTTT TAAGGCTAAA 120GTCCTTGATT CTAAAGAACC AAGACAAGTT TTAGGCGTTT ATAATATCTC CCCACACAAA 180AAACTCACGC TCACTATCAC TCACATATCC ACGGCAATCG TCTATCAACC CCTTGATGAA 240AAACTTTCTT TAGAAACGAC CTTAAGCCCT AACCGCCCTA CTATCCCTAG AAACACCCAA 300ATCGTTTTTT CTTCAAAAGA ATTGAAAGAA CCGCACTCAA ACCCAATACC TTCTTTAAAC 360GCGCCCATGC AAAAACCACA AAATAAACCC AGCTCATCGC AACAATCTCC TCAAAACTTT 420TCTTACCCAG AGTCCAAACT AGGCTCTAAA AACTCTAAAA ACAGCCTTTT ACAGCCTTTA 480GTAACTCCTA GCAAAGTAAG CCCCACTAAC GAAGTTAAAA CGCCAACAAA CGACGCTAAT 540CCCCCTTTAA AGCATTCTTC ACAAGATCAA GAAAACAACC TCTTTGTAGC GCCACCCACT 600GAAAAAACGC TCCCTAACAA CACCTCTAGT GCTGATGCGA GTGAAAACAA TGAAAGCAAC 660GAAAATAGGG ATAATGTGGA AAAACAAGCG ATTAGAGATC CTAATATCAA AGAATTCGCA 720TGCGGGAAGT GGGTTTATGA TGATGAAAAT TTACAAGCCT ATCGCCCAAG CATTTTAAAA 780CGCGTTGATA AAGACAAAGA GATTACAACA GACATTACCC CTTGCGATTA CAGCACCGCT 840GAAAATAAAA GCGGTAAAAT CATTACCCCC TATACTAAAA TCTCTGTTCA TAAAACAGAG 900CCTTTAGAAG ACCCTCAAAC TTTTGAAGCT AAAAATAATT TCGCCATTCT CCAAGCCAGA 960AGCTCTACAG AAAAGTGTAA AAGGGCTAGA GCGAGAAAAG ACGGCACGAC CAGGCAATGC 1020TATCTGATAG AAGAGCCTTT AAAACAAGCG TGGGAGAGCG AGTATGAAAT CACCACGCAA 1080TTAGTGAAAG CCATATATGA ACGCCCCAAA CAAGACGATC AAGTAGAGCC GACTTTTTAT 1140GAAACCAGCG AATTGGCTTA TTCTTCCACA CGAAAAAGCG AAATAACGCG TAATGAATTG 1200AATTTGAATG AAAAATTCAT GGAATTTGTG GAAGTGTATG AGGGGCATTA TTTAAACGAT 1260ATAATCAAAG AGAGCAGCGA ATACAAAGAA TGGGTTAAAA ACCATGTGCG CTTTAAAGAA 1320GGGGTGTGCA TGGCCTTAGA AATAGAAGAG CAACCACGAG CCAAAAGCAC GCCTTTGAGT 1380ATTGAAAACT CTCGTGTTGT GTGTGTCAAA AAGGGGAATT ATTTATTCAA TGAAGTTTAA 1440(2) SEQ ID NO 994 information

Sequence properties:

(A) length: 810 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...810

(xi) sequence representation: SEQ ID NO 994: GTGAAAGTTT ATCCGCAAGT TTTAAGCATT GCTGGTAGCG ATAGCGGTGG GGGCGCTGGG 60ATACAGGCCG ATTTGAAAGC GTTTCAAACT TTTGGCGTGT TTGGGACAAG CGTGATCACT 120TGCATCACCG CTCAAAACAC ACAGGGCGTG CATGGGGTGT ATCCATTGAG TGTAGAGAGC 180GTGAAAGCGC AAATCCTAGC TATTAGAGAT GATTTTTCGA TCAAGGCGTT CAAAATGGGG 240GCGTTATGCA ACGCTCAAAT CATTGAATGC GTAGCGAACG CTTTAGAAAC TTGTGATTTT 300GGGTTGTGCG TTTTAGATCC GGTGATGGTG GCAAAGAATG GGGCTTTGCT TTTAGAAGAG 360GAGGCGATTT TAAGCTTAAA AAAACGCCTT TTACCTAAAA CCAATTTACT AACCCCTAAC 420CTCCCTGAAG TCTATGCGCT CACAGGCGTT CAAGCGCGAG ACGATAAAAG CGCTTCAAAA 480GCGATGGGTG TTTTAAGGGA TTTAGGCGTT AAAAACGCTG TGATTAAAGG GGGGCATACA 540GAACATTTTC AAGGGGAATT TAGCAACGAT TGGGTGTTTT TAGAAGACGC TGAATTTATC 600TTAAGCGCCA AGCGATTCAA CACCAAAAAC ACGCATGGCA CGGGTTGTAC TTTGTCTAGC 660TTGATTGTGG GCTTACTCGC TCAAGGGCTG GATTTAAAAA ACGCTATCAC AAAGGCTAAA 720GAGCTTTTAA CTATCATCAT TCAAAACCCC TTAAACATTG GGCATGGGCA TGGGCCTTTG 780AATTTGTGGA GCATCAAAAA GCATGTTTGA 810(2) SEQ ID NO 995 information

Sequence properties:

(A) length: 1197 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1197

(xi) sequence representation: SEQ ID NO:995: TTGGGGGCTA TCATGGATAC TTTTTTAACA AGTATCTTGG TCCTGCTTAT GCGGGGACTT 60CTCAATCAGC GAGCTATCAT GCAAGGCCTT ATGTGGTGGA TACCGCTTTT TTACGATACG 120ATTACCAAAG ATGTTTTTGG GTTTAAGGCG GGGCGCTATG AAGCGAATAT TGATTTCATG 180AGCGGTTCGA ATCAAGGGTG GGAAGTGTAT TATCAGCCCT ATAAGACTGA GACGCAAAGG 240TTAAGGTTTT GGTGGTGGAG TTCTTTTGGG AGAGGTTTGG CGTTTAACTC TTGGATTTAT 300GAGTTTTTTG CGACCGTGCC TTATTTGAAA AAGGGAGGCA ACCCTAGTAA CAGCAACGAT 360TTCATCAATT ATGGCTGGCA TGGGATCACC ACGACTTATT CTTATAAAGG TTTAGACGCT 420CAATTTTTTT ATTATTTTGC ACCTAAAACT TATAACGCTC CCGGTTTTAA GCTAGTCTAT 480GACACGAATA GGAATTTTGA AAACGTAGGC TTTCGCTCTC AAAGCATGAT CATGACGACC 540TTCCCTTTAT ATTATAGGGG GTGGTATAAC CCAGAGACAA ACACTTATAG CTTAGAAGAC 600AGCACGCCTC ATGGCTCTTT GTTAGGGAGG AATGGCGTTA CTTTAAATAT CCGCCAGGTT 660TTTTGGTGGG ATAATTTCAA CTGGTCCATT GGCTTTTATA ACACCTTTGG CAATTCAGAC 720GCTTTTTTAG GCTCTCACAC CATGCCAAGG GGGAATAACA CTTCCTATAT CAGTAATGAA 780ATCTCAGTAA CGACTAGGCA TGCCGGAATG ATCGGCTATG ATTTTTGGGA TAATACGGCT 840TATGATGGGC TGGCTGATGC GATCACTAAC GCGAACACTT TCACTTTTTA CACTTCGGTT 900GGAGGGATCC ATAAGCGTTT TGCATGGCAT GTTTTTGGGC GCGTCTCTCA TGCGAATAAA 960AATGCGTTAG GGCAAGTGGG GAGGGCTAAT GAATATTCCT TGCAATTCAA TGCGAGCTAT 1020GCGTTCACTG AATCGGTTCT CCTTAACTTT AGGATCACTT ATTATGGGGC TAGGATCAAT 1080AAAGGGTATC AAGCAGGGTA TTTTGGAGCG CCCAAATTCA ATAACCCGGA TGGCGATTTT 1140AGCGCTAATT ACCAAGACAG AAGTTACATG ATGACCAACC TCACGCTGAA GTTTTGA 1197(2) SEQ ID NO:996 of the user.

Sequence properties:

(A) length: 1335 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1335

(xi) sequence representation: SEQ ID NO 996: TTGAGTAACG CTTTCTCCCA ATACCTTTAT TCGCTTTTAG GGGCGTATCC CACGAAACTC 60AATGGTAACG ACGTGTCTGC GAACGCTCTT TTAAGTGGTG CGGTAGGCAG TGGGACTTGC 120GCGGCTGCAG GGACGGCTGG TGGCACAACT CTTAACACTC AAAGCGCTTG CACCGCTGCG 180GGCTATTACT GGCTCCCTAG CTTGACTGAT AGGATTTTAA GCACGATCGG CAGCCAGACT 240AACTACGGCA CGAACACCAA TTTCCCCAAC ATGCAACAAC AGCTCACCTA CTTGAATGCG 300GGGAATGTGT TTTTTAATGC GATGAATAAG GCTTTAGAGA AGAATGGGAC TGCTACTGCT 360AATAGCACTA GTAGCACTAG CGGTGCGACT GGTTCAGATG GTCAAACTTA CTCTCAACAA 420GCTATTCAAT ACCTTCAAGG CCAACAAAAT ATCTTAAATA ACGCAGCGAA CTTGCTCAAG 480CAAGATGAAT TGCTCCTAGA AGCTTTCAAC TCTGCCGTAG CTGCTAACAT TGGGAATAAG 540GAATTCAATT CAGCCGCTTT TACAGGTTTG GTGCAAGGCA TTATTGATCA ATCTCAATTG 600GTTTATAACG AGCTCACTAA AAACACCATT AGCGGGAGCG CGGTTAATAA CGCTGGGATA 660AACTCCAACC AAGCTAACGC TGTGCAAGGG CGTGCTAGTC AGCTCCCTAA CGCTCTTTAT 720AACGTGCAAG TAACTTTGGA TAAAATCAAC GCGCTCAACA ATCAGGTGAG AAGCATGCCT 780TACTTGCCCC AATTCAGAGC CGGGAACAGC CGTGCAACGA ATATTTTAAA CGGGTTTTAC 840ACTAAAGTGG GCTATAAGCA ATTCTTCGGG AAGAAAAGGA ATATCGGTTT GCGCTATTAT 900GGTTTCTTTT CTTATAACGG AGCGAGCGTG GGCTTTAGAT CCACTCAAAA TAATGTAGGG 960TTATACACTT ATGGGGTGGG GACTGATGTG TTGTATAACA TCTTTAGCCG CTCCTATCAA 1020AACCGCTCTG TGGATATGGG CTTTTTTAGC GGTATCCAAT TAGCCGGTGA GACCTTCCAA 1080TCCACGCTCA GAGATGACCC CAATGTGAAA TTGCATGGGA AAATCAATAA CACGCACTTC 1140CAGTTCCTCT TTGACTTCGG TATGAGAATG AACTTCGGTA AGTTGGACGG GAAATCCAAC 1200CGCCACAACC AGCACACGGT GGAATTTGGC GTAGTAGTGC CTACGATTTA TAACACTTAT 1260TACAAATCAG CAGGGACTAC CGTGAAGTAT TTCCGTCCTT ATAGCGTTTATTGGTCTTAT 1320GCGTATTCAT TCTAA 1335(2) SEQ ID NO 997 message

Sequence properties:

(A) length: 402 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...402

(xi) sequence representation: SEQ ID NO 997: ATGGAGTTAA TTAAGAAATT GGAAAAAGAA AGCGAAGTTT TAAAGAAAGA TTTACAACAA 60CATTCAAACG AGCTTTTTAA AATGTTGATT ATTGATAATG AAGATTTGTT TAAAGAGCAA 120TTTGAGATTA TGTTTAAAGC ATGGGTTGAA ATCGTAAAAA TGATGTTTGA ATTAACCAAA 180AAAACCAAAT TTGATGGCGA AATGATTGGC TACACAGAAG AACTTTTAAC CTTTTTAGTT 240AGAGATTTTT TTAATGGGAT TTTTAAATCC AAAGTAATAC CTAAAATGCC TATTTTTTGC 300GGTGATGTTA AATGCGAAGA TTTTAATGCC CTAAGAAGTT TAGTTTATCT TTCTGTGCTT 360GAGTTGGAAG AAACGATAAA TCCTAATAAA ATCCCATTTT AA 402(2) information of SEQ ID NO 998

Sequence properties:

(A) length: 2091 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: isfree of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2091

(xi) sequence representation: SEQ ID NO 998: ATGAAAATCA AAAAATCCCT CTTTGCTCTC TCTTTCTCTC TCATGGCTTC ATTATCAAGG 60GCTGAAGATG ACGGATTTTA CATGAGTGTG GGCTATCAAA TCGGTGAAGC GGTCCAAAAA 120GTGAAAAACA CTGGAGCATT ACAAAATCTT GCAGACAGAT ACGATAACTT GAGCAACCTT 180TTAAACCAAT ACAATTACTT AAATTCCTTA GTCAATCTAG CCAGCACGCC TAGCGCGATT 240ACCGGTGCGA TTGACAATCT AAGCTCAAGC GCGATCAATC TCACTAGCGC TACCACCACT 300TCTCCGGCCT ATCAAGCTGT GGCTTTAGCG CTCAATGCGG CTGTGGGCAT GTGGCAAGTC 360ATAGCCTTTG GCATCAGCTG TGGCCCTGGC CCCAATCTTG GCCCAGAACA TTTAGAAAAT 420GGGGGCGTTC GATCGTTTGA CAACACGCCA AACTACAGCT ACAACACCGG TAGCGGAACG 480ACCACCACCA CTTGTAATGG AGCCAGTAAT GTAGGGCCCA ATGGTATCCT ATCTAGCAGC 540GAATACCAGG TTCTCAATAC CGCTTATCAA ACTATCCAAA CCGCTTTAAA CCAAAACCAA 600GGAGGCGGGA TGCCTGCCTT GAATAGCTCC AAAAATATGG TAGTCAATAT CAATCAAACT 660TTCACAAAAA ACCCTACCAC AGAATACACT TACCCCGATG GGAATGGCAA TTATTATTCA 720GGCGGTTCAT CAATCCCAAT CCAGCTAAAG ATTAGTAGCG TCAATGACGC TGAAAACCTT 780TTGCAACAAG CCGCTACTAT CATCAATGTC CTTACCACCC AAAACCCGCA TGTGAATGGT 840GGCGGTGGGG CATGGGGGTT TGGCGGTAAG ACCGGGAATG TGATGGATAT TTTTGGCGAT 900AGTTTTAACG CTATTAACGA AATGATCAAA AACGCTCAAG CCGTTTTAGA AAAAACCCAA 960CAGCTTAACG CTAATGAAAA CACCCAAATC ACGCAACCAG ACAATTTCAA CCCCTACACT 1020TCTAAAGACA CGCAGTTCGC TCAAGAAATG CTCAATAGAG CTAACGCTCA AGCAGAGATT 1080TTGAGCTTAG CCCAACAAGT AGCGGACAAT TTCCACAGCA TTCAAGGGCC TATCCAACAA 1140GATCTAGAAG AATGCACCGC AGGATCAGCT GGTGTGATTA ACGACAACAC TTATGGTTCA 1200GGTTGCGCGT TTGTGAAAGA GACTCTCAAT TCCTTAGAGC AACACACCGC TTATTATGGC 1260AACCAGGTCA ATCAGGATAG GGCTTTGTCT CAAACCATTT TGAATTTTAA AGAAGCCCTT 1320AGCACTTTAG GGAACGACTC AAAAGCGATC AATAGCGGTA TCTCTAACTT GCCTAACGCT 1380AAGTCCCTTC AAAACATGAC GCATGCCACT CAAAACCCTA ATTCCCCAGA AGGTTTGCTC 1440ACTTATTCTT TGGATACCAG CAAATACAAC CAGCTCCAAA CTGTTGCGCA AGAATTAGGC 1500AAAAACCCCT TTAGGCGCAT CGGCGTGATT AACTATCAAA ACAATAACGG GGCGATGAAC 1560GGCATCGGCG TGCAAGCGGG CTATAAGCAA TTCTTTGGCA AAAAAAGGAA TTGGGGGTTA 1620AGGTATTATG GTTTCTTTGA TTATAACCAT GCTTATATCA AATCTAATTT TTTTAACTCG 1680GCTTCTGATG TGTGGACTTA TGGGGTGGGT ATGGACGCGC TTTATAACTT CATCAACGAT 1740AAAAACACCA ACTTTTTAGG CAAAAATAAC AAGCTTTCTG TGGGGCTTTT TGGTGGCTTT 1800GCGTTAGCCG GGACTTCGTG GCTTAATTCC CAACAAGTGA ATTTGACCAT GATGAATGGC 1860ATTTATAACG CTAATGTCAG CGCTTCTAAC TTCCAATTTT TGTTTGATTT AGGCTTGAGA 1920ATGAACCTCG CTAGGCCCAA GAAAAAAGAC AGCGATCATG CCGCTCAGCA TGGCATGGAA 1980TTGGGCGTGA AAATCCCCAC CATTAACACG GATTATTATT CTTTCATGGG GGCTGAACTC 2040AAATACAGAA GGCTCTATAG CGTGTATCTC AATTATGTGT TTGCTTACTA G2091 (2) SEQ ID NO 999 information

Sequence properties:

(A) length: 1116 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1116

(xi) sequence representation: SEQ ID NO:999: ATGCAATTTC AAAAAACCTT ATCTTCCTTA TCTTTATTTT TATCTTTATC TTTATTCTTA 60TCTTTTAGTA TCGCTGAAGA AAATGGGGCG TATGCGAGCG TGGGTTTTGA ATATTCCATC 120AGTCATGCCG TTGAACACAA TAACCCTTTT TTGAATCAAG AACGCATCCA AACGATTTCT 180AACGCTCAAA ACAAAATCTA TAAACTCAAT CAAGTCAAAA ATGAAATCAC AAACATGCCC 240AACACCTTTA ACTACATCAA CAACGCTTTA AAAAACAATG CTAAATTAAC CCCTACTGAA 300AAGCAAGCCG AAACCTACTA CCTGCAATCT ACCCTTCAAA ACATTGAAAA AATAGTCATG 360CTTAGCGGGG GCGTTGCGTC TAACCCTAAA TTAGCCCAAG CGTTAGAAAA AATGCAAGAA 420CCCATTACTA ACCCTTTAGA ATTGGTAGAA AACTTAAAAA ATTTAGAATT ACAATTCAGC 480CAATCTCAAA ACAGCATGCT TTCTTCTTTG TCTTCTCAGA TCGCTCAAAT TTCAAATTCT 540TTGAACGCGC TTGATCCCAG CTCTTATTCT AAAAACGTTT CAAGCATGTA TGGGGTAGGT 600TTGAGCGTAG GGTATAAGCA TTTCTTTACC AAGAAAAAAA ATCAAGGGTT TCGTTATTAC 660TTATTCTATG ACTATGGTTA CACTAATTTT GGTTTTGTGG GTAATGGCTT TGATGGTTTA 720GGCAAAATGA ATAACCACCT CTATGGGCTT GGCATAGATT ATCTTTTCAA TTTCATTGAT 780AATGCGCAAA AACATTCGAG CGTGGGGTTT TATGTAGGCT TTGCTTTAGC GGGGAGTTCG 840TGGGTAGGGA GTGGTTTAGG CATGTGGGTG AGTCAAATGG ATTTCATCAA CAACTATTTG 900ACGGATTATC GGGCTAAAAT GCACACGAGT TTTTTTCCAA TCCCTTTGAA TTTTGGGGTT 960CGTGTGAATG TGGATAGGCA CAATGGCTTT GAAATGGGCT TAAAGATCCC TTTAGCGGTC 1020AATTCCTTTT ATGAAACGCA TGGCAAAGGG TTAAACGCTT CCCTCTTTTT CAAACGCCTT 1080GTCATGTTTA ACGTGAGTTA TGTTTATAGT TTTTAG 1116(2) SEQ ID NO:1000 information.

Sequence properties:

(A) length: 1455 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1455

(xi) sequence representation: 1000: ATGGCTAAAA TCACAACCGT GATTGACATA GGCTCTAATT CAGTGCGTTT GGCTGTCTTT 60AAAAAGACGA GCCAGTTTGG GTTTTACTTG CTTTTTGAGA CTAAGTCCAA GGTTAGGATT 120TCAGAGGGCT GTTATGCGTT TAAAGGGGTT TTACAAGAAA TCCCCATGCA ACGAGCCGTT 180AAAGCCTTGA GCGAATTTAA AGAAATCGCC CTCAAATACA AAAGCAAAAA AATCCTGTGC 240GTGGCGACCT CAGCGGTGCG CGATGCCCCT AATCGGTTAG AGTTTGTAGC GAGGGTGAAA 300AAGGCTTGCG GTTTGCAAAT CAAAATCATT GATGGGCAAA AAGAAGCGCT CTATGGTGGG 360ATCGCGTGCG CGAATTTGCT GCATAAAAAT TCAGGGATCA CGATAGACAT TGGAGGGGGT 420AGCACCGAGT GCGCGTTGAT TGAGAAAGGT AAGATTAAGG ACTTAATCTC GCTTGATGTC 480GGGACGATTC GCATTAAAGA AATGTTTCTA GACAAAGACT TAGATGTCAA ATTGGCTAAA 540GCCTTTATCC AAAAAGAGGT CTCTAAACTG CCTTTTAAGC ATAAAAACGC CTTTGGGGTG 600GGGGGGACGA TCAGAGCCTT GAGTAAGGTG CTGATGAAAC GCTTTGATTA CCCTATAGAT 660TCTTTGCATG GCTATGAAAT AGATGCGCAT AAAAATTTAG CGTTCATTGA AAAAATCGTC 720ATGCTCAAAG AAGACAAATT ACGGCTTTTA GGGGTGAATG AAGAGCGTTT GGATAGCATT 780AGGAGCGGGG CGTTGATTTT ATCAGTCGTG TTAGAGCATT TGAAAACTTC CTTGATGATC 840ACTAGCGGGG TAGGGGTGAG AGAGGGCGTG TTTTTGAGCG ATTTATTGCG CCACCATTAC 900CATAAATTCC CCCCCAATAT CAACCCCTCT CTCATCTCTC TAAAAGATCG CTTTTTACCC 960CATGAAAAGC ACAGCCAAAA GGTCAAAAAA GAATGCGTGA AATTGTTTGA AGTTTTATCG 1020CCTTTGCATA AAATAGATGA AAAATACCTT TTCCATTTAA AGATTGCGGG GGAATTGGCG 1080AGCATGGGTA AGATTTTAAG TGTATATTTA GCCCACAAGC ACAGCGCGTA TTTCATTTTA 1140AACGCTTTGA GTTACGGCTT TAGCCACCAG GATAGGGCGA TCATTTGCTT ATTGGCGCAA 1200TTTAGCCATA AAAAAATCCC TAAAGACAAC GCTATCGCCC ACATGAGTGC GATGATGCCA 1260AGCCTTTTGA CCTTGCAGTG GCTGAGTTTT ATCCTTTCTT TAGCCGAAAA TTTGTGCCTG 1320ACAGACAGCC ATCATTTAAA ATACACGCTA GAAAAAAACA AGCTTGTGAT CCATTCTAAT 1380GATGCGCTTT ACTTGGCTAA AGAAATGCTC CCCAAACTCA TTAAGCCCAT TCCTTTGACG 1440ATAGAGTTTG CTTGA 1455(2) SEQ ID NO 1001 information

Sequence properties:

(A) length: 762 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...762

(xi) sequence representation: SEQ ID NO:1001: AAACAGGTTA AATCTCGCAT GAAAGAAAAG CCGTTCAATA GCGAGCAGAT GGCTTTTTTA 60GAAGAGCTTT TAAGCCACCA AGAAAAGCAT TTAGAGAGCA AGCTTTCTGG TTTTTCGGTG 120AATGATTTGG ACATGCAAAG CGTGTTTCGG CTAGAAAGGA ACCGCTTGAA AATCGCTTAC 180AGGCTTTTAG GTTTGATGAG CTTTATCGCG CTTGTCTTAG CGATCGTTTT AATCAGTATC 240CTGCCCTTAC AAAAAACCGA ACACCATTTC GTGGATTTTT TAAACCAGGA CAAGCATTAC 300GCCATTATCC AAAGAGCGGA TAAAAGCATT TCCAGTAATG AAGCGTTGGC TCGTTCGCTC 360ATTGGGGCGT ATGTGTTAAA CCGAGAGAGC ATTAATCGCA TTGACGATAA ATCCCGCTAT 420GAACTGGTGC GCTTGCAAAG CAGCTCTAAA GTGTGGCAAC GCTTTGAAGA TTTGATTAAA 480GCCCAAAACA GCATCTATGT GCAAAGCCAT TTAGAAAGAG AAGTCCATAT CGTCAATATT 540GCGATCTATC AGCAAGACAA TAACCCCATT GCGAGCGTGT CCATTGCGGC TAAACTTTTG 600AATGAAAACA AGCTCGTGTA TGAAAAGCGT TATAAAATCG TATTGAGCTA TTTGTTTGAC 660ACCCCGGATT TTGATTACGC TTCCATGCCT AAAAACCCTA CCGGCTTTAA AATCACTCGC 720TACAGCATCA CTGAAATCGC GCCGACTAAT AGGAATGATT GA 762(2) SEQ ID NO:1002 information

Sequence properties:

(A) length: 1440 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1440

(xi) sequence representation: SEQ ID NO 1002: ATGAAAAAAT CCCTTTGTTT GTCTTTCTTT CTGACCTTCT CTAACCCTCT TCAAGCCCTT 60GTCATTGAGC TTTTAGAAGA GATTAAAACT TCGCCGCATA AAGGCACTTT TAAGGCTAAA 120GTCCTTGATT CTAAAGAACC AAGACAAGTT TTAGGCGTTT ATAATATCTC CCCACACAAA 180AAACTCACGC TCACTATCAC TCACATATCC ACGGCAATCG TCTATCAACC CCTTGATGAA 240AAACTTTCTT TAGAAACGAC CTTAAGCCCT AACCGCCCTA CTATCCCTAG AAACACCCAA 300ATCGTTTTTT CTTCAAAAGA ATTGAAAGAA CCGCACTCAA ACCCAATACC TTCTTTAAAC 360GCGCCCATGC AAAAACCACA AAATAAACCC AGCTCATCGC AACAATCTCC TCAAAACTTT 420TCTTACCCAG AGTCCAAACT AGGCTCTAAA AACTCTAAAA ACAGCCTTTT ACAGCCTTTA 480GTAACTCCTA GCAAAGTAAG CCCCACTAAC GAAGTTAAAA CGCCAACAAA CGACGCTAAT 540CCCCCTTTAA AGCATTCTTC ACAAGATCAA GAAAACAACC TCTTTGTAGC GCCACCCACT 600GAAAAAACGC TCCCTAACAA CACCTCTAGT GCTGATGCGA GTGAAAACAA TGAAAGCAAC 660GAAAATAGGG ATAATGTGGA AAAACAAGCG ATTAGAGATC CTAATATCAA AGAATTCGCA 720TGCGGGAAGT GGGTTTATGA TGATGAAAAT TTACAAGCCT ATCGCCCAAG CATTTTAAAA 780CGCGTTGATA AAGACAAAGA GATTACAACA GACATTACCG CTTGCGATTA CAGCACCGCT 840GAAAATAAAA GCGGTAAAAT CATTACCCCC TATACTAAAA TCTCTGTTCA TAAAACAGAG 900CCTTTAGAAG ACCCTCAAAC TTTTGAAGCT AAAAATAATT TCGCCATTCT CCAAGCCAGA 960AGCTCTACAG AAAAGTGTAA AAGGGCTAGA GCGAGAAAAG ACGGCACGAC CAGGCAATGC 1020TATCTGATAG AAGAGCCTTT AAAACAAGCG TGGGAGAGCG AGTATGAAAT CACCACGCAA 1080TTAGTGAAAG CCATATATGA ACGCCCCAAA CAAGACGATC AAGTAGAGCC GACTTTTTAT 1140GAAACCAGCG AATTGGCTTA TTCTTCCACA CGAAAAAGCG AAATAACGCG TAATGAATTG 1200AATTTGAATG AAAAATTCAT GGAATTTGTG GAAGTGTATG AGGGGCATTA TTTAAACGAT 1260ATAATCAAAG AGAGCAGCGA ATACAAAGAA TGGGTTAAAA ACCATGTGCG CTTTAAAGAA 1320GGGGTGTGCA TGGCCTTAGA AATAGAAGAG CAACCACGAG CCAAAAGCAC GCCTTTGAGT 1380ATTGAAAACT CTCGTGTTGT GTGTGTCAAA AAGGGGAATT ATTTATTCAA TGAAGTTTAA 1440(2) SEQ ID NO 1003 information

Sequence properties:

(A) length: 1704 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1704

(xi) sequence representation: SEQ ID NO 1003: ATGATTTTTG GGGATTTTAA ATATCAAAAA AGCGTTAAAA AACTCACAGC CACTAACCTT 60AACGAGCTTA AAAACGCCCT GGATTTTATC TCTCAAAATA GGGGGAAGGG GTATTTTGTG 120GGGTATCTTT TGTATGAAGC GCGCTTAGCG TTTTTAGATG AAAATTTTCA AAGCCAAACC 180CCTTTTTTGT ATTTTGAACA ATTTTTAGAA AGAAAAAAAT ACCCTTTAGA GCCTTTAAAA 240GAGCATGCGT TTTACCCTAA AATCCACAGC TCTTTAGATC AAAAAACTTA TTTCAAGCAG 300TTTAAGGCCG TTAAAGAGCA TCTCAAAAAC GGCGATACCT ATCAAGTGAA TTTGACAATG 360GATTTATTGT TAAACACTAA AGCCAAACCA AAGCGCGTTT TTAAGGAAGT GATACACAAC 420CAAAACACGC CTTTTAAGGC TTTTATAGAA AATGAGTTTG GGAGCGTTTT AAGCTTTTCG 480CCGGAATTGT TTTTTGAATT AGAGTTTTTA GACACAGCGA TTAAGATTAT CACAAAACCC 540ATGAAAGGCA CGATCGCTCG CTCAAACAAC CCCTTGATAG ATGAAAAAAA CCGATTGTTT 600TTGCAAAATG ATGACAAAAA TAGAAGCGAA AATGTGATGA TCGTGGATTT ATTGCGTAAC 660GATTTGAGCC GCTTGGCCTT AAAAAATAGC GTGAAAGTCA ATCAATTGTT TGAAATCATC 720AGTTTGCCGA GCGTGTATCA AATGATAAGC GAGATTGAAG CTCAATTGCC CCTAAAAACA 780AGCTTGTTTG AGATTTTTAA GGCGTTGTTC CCTTGCGGCT CTGTGACCGG ATGCCCTAAA 840ATCAAAACCA TGCAAATCAT TGAAAGTTTA GAAAAACGCC CTAGGGGGGT GTATTGTGGG 900GCGATAGGCA TGGTTGGAGG AAAAAAAGCC CTTTTTAGCG TGCCTATCCG CACTTTAGAA 960AAAAGAGCGC ATGAAGATTT TTTGCATTTA GGGGTAGGGA GTGGGGTAAC TTATAAAAGT 1020AAAGCTTCAA AGGAATATGA AGAGAGCTTT TTAAAATCCT TTTTTGTGAT GCCCAAAATA 1080GAATTTGAGA TCGTGGAAAC GATGAGAGTT ATCAAAAGGG ATCAAAAATT AGAGATTAAC 1140AATAAAAACG CCCATAAAGA ACGCTTAATG CATAGCGCCC AATATTTTAA CTTTAAATAC 1200GATGAAAATC TTTTAGACTT TGAATTAGAA AAAGAAGGGG TTTTAAGGGT TTTACTCAAT 1260AAAAGGGGCA AGCTCATTAA AGAATACAGA ACCTTAGAGC CTTTAAAAAG CCTAGAAATC 1320CGTTTGAGTG AAGCCCCCAT TGACAAACAC GATGATTTTT TATACCATAA GACCGCTTAT 1380GCCCCTTTTT ATCAAAACGC TCGAGCGCTC ATTAAAAAAG GCGTTATTTT TGATGAAATC 1440TTTTATAACC AGGATTTGGA ACTCACTGAG GGCGCTAGGA GTAATCTTAT TTTAGAAATC 1500CACAACAGGC TTTTAACCCC TTATTTCAGC GTGGGCGCAT TAACCGGGAC GGGCGTTGTG 1560GGGTTGTTAA AAAAAGGTCT TGTTGAGCAT GCCCCTTTAA AATTACAAGA CTTGCAAAGA 1620GCGGCTAAAA TCTATTGTAT TAACGCGCTA TACGGCTTAG TGGAGGTGGG AATAATAGGT 1680TACCCAATGG AGCAAAAAAG TTAA 1704(2) SEQ ID NO 1004 information

Sequence properties:

(A) length: 1125 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1125

(xi) sequence representation: SEQ ID NO:1004: ATGAAAATCA GTGTTAGTAA AAACGATTTA GAAAACACTT TGCGCTACTT GCAAGCTTTT 60TTGGATAAAA AGGACGCTTC CTCTATCGCT TCACACATCC ATTTAGAAGT CATTAAAGAA 120AAGCTCTTTT TAAAAGCCAG CGATTCAGAT ATTGGACTAA AAAGCTATAT TTCTACGCAA 180TCTACCGATA AAGAGGGCGT AGGCACGATC AACGGGAAGA AGTTTTTAGA TATTATCTCA 240TGTTTGAAAG ACTCTAATAT TGTTTTAGAG ACTAAAGATG ACAGCTTGGT GATCAAACAA 300AATAAAAGCT CTTTCAAACT CCCCATGTTT GACGCTGATG AGTTCCCTGA ATTCCCTGTT 360ATTGATCCAA AAGTGAGTTT AGAAATCAAT GCCCCCTTTT TGGTGGATGC GTTTAAAAAG 420ATCGCTCCTG TGATTGAGCA AACTAGCCAT AAAAGGGAAT TAGCCGGTGT TTTAATGCAA 480TTCAATCAAA AACACCAAAC CCTTTCAGTG GTAGGCACGG ATACCAAGCG GCTCTCTTAC 540ACGCAGTTAG AAAAAATCTC TATCCATTCC ACCGAAGAAG ACATCTCTTG CATTTTGCCT 600AAAAGGGCTT TATTGGAAAT CCTTAAACTT TTTTATGAAA ATTTCAGTTT TAAAAGCGAC 660GGCATGTTAG CGGTGGTTGA AAACGAAACG CACGCTTTTT TCACCAAGCT CATTGATGGG 720AATTACCCTG ATTATCAAAA AATCCTCCCT AAAGAATACA CTTCTTCTTT CACTTTAGGC 780AAGGAAGAAT TTAAAGAGGG CATTAAGTTG TGCAGTTCTT TAAGCTCCAC CATTAAGCTC 840ACTTTAGAAA AAAACAACGC TTTGTTTGAA TCTTTGGATT CTGAGCATAG CGAAACCGCC 900AAAACCTCTG TTGAGATTGA AAAAGGTTTG GATATTGAAA AAGCCTTTCA TTTGGGCGTG 960AACGCAAAAT TTTTCCTTGA AGCCTTAAAC GCTTTAGGGA CAACGCAATT TGTTTTAAAA 1020TGCAATGAGC CTTCTTCGCC TTTTTTGATT CAAGAACCTC TTGATGAAAA GCAAAGCCAC 1080TTGAACGCTA AAATTTCCAC TTTGATGATG CCAATCACAC TATAA 1125(2) SEQ ID NO:1005 information.

Sequence properties:

(A) length: 1107 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1107

(xi) sequence representation: SEQ ID NO:1005: ATGGTTGTTT TAGGAAGCAC CGGCTCTATC GGGAAAAACG CCCTTAAAAT CGCAAAAAAA 60TTTGGTGTAA AAATAGAAGC CTTAAGCTGT GGGAAAAATA TCGCTTTAAT CAATGAACAA 120ATCAAAGTTT TCAAACCCAA AAAAGTAGCG ATCTTAGATC CTAACGATTT GAATAATTTA 180GAGCCTTTGG GCGCGGAAGT GTTTGTGGGG TTAGACGGCA TTGATGCGAT GATAGAGGAG 240TGCGTTTCCA ATTTAGTCAT TAACGCCATT GTGGGCGTAG CCGGATTGAA AGCGAGCTTT 300AAAAGCTTAC AAAGGAACAA AAAACTAGCC CTAGCGAATA AAGAAAGTTT AGTGAGCGCG 360GGGCATTTAT TAGACATTTC ACAAATCACG CCCGTTGATA GCGAGCATTT TGGTTTGTGG 420GCGTTGTTGC AAAACAAGAC TTTAAAGCCT AAATCTTTAA TCATTAGCGC GAGTGGGGGG 480GCTTTTAGGG ACACGCCCTT AGATCTTATC GCTATTCAAA ATGCGCAAAA CGCGCTCAAG 540CACCCTAATT GGAGCATGGG GGATAAAATC ACCATTGATT CAGCGAGCAT GGTCAATAAA 600CTTTTTGAAA TTTTAGAAAC CTATTGGCTT TTTGGTGCGT CTTTAAAGAT TGACGCGCTG 660ATTGAAAGAA GTTCTATCGT GCATGCTTTG GTGGAGTTTG AAGACAACTC TGTCATTGCG 720CATTTAGCGA GTGCGGACAT GCAATTACCC ATAAGCTATG CCATTAACCC TAAATTAGCT 780TCTTTGAGTG CTTCCATTAA ACCCTTAGAT TTATACGCTT TAAGCGCGAT TAAATTCGAA 840CCCATTAGCG TGGAGCGCTA CACTTTGTGG CGTTATAAAG ATTTGTTGTT GGAAAACCCA 900AAGCTTGGCG TGGTGCTGAA TGCGAGCAAT GAAGTGGCGA TGAAGAAGTT CTTGAATCAA 960GAAATCGCTT TTGGTGGCTT TATCCAAATC ATCTCTCAAG CTTTAGAATT GTATGCTAAA 1020AAATCTTTCA AGCTCTCTAG TTTAGATGAA GTGCTAGCGT TAGATAAGGA AGTTAGGGAG 1080CGTTTTGGAA GTGTAGCGAG AGTGTAG 1107(2) SEQ ID NO:1006 information.

Sequence properties:

(A) length: 1254 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1254

(xi) sequence representation: SEQ ID NO 1006: ATGAAATATT TATGGCTTTT TTTAATATAC GCTATAGGGC TTTTTGCAAC AGATAAAACG 60CTAGATATTA TTAAAACCAT TCAAAAACTT CCTAAGATTG AAGTGCGCTA CTCCATAGAT 120AACGATGCCA ATTACGCTTT AAAATTGCAT GAAGTCTTAG CGAACGATTT AAAGACTAGC 180CAGCATTTTG ATGTTTCTCA AAACAAAGAG CAAGGTGCTA TCAATTACGC AGAACTCAAG 240GATAAAAAAG TCCATCTTGT AGCGCTTGTG AGCGTGGCGG TAGAAAACGG CAATAAAATT 300TCACGATTAA AACTTTATGA TGTGGATACA GGAACGCTCA AAAAGACTTT TGACTACCCC 360ATTGTAAGTT TAGATCTATA CCCTTTTGCA GCGCACAACA TGGCCATTGT GGTGAATGAT 420TATTTAAAAG CCCCTTCTAT CGCTTGGATG AAGCGCCTGA TTGTTTTTTC TAAATACATT 480GGACCAGGAA TCACAAACAT CGCACTAGCG GATTATACGA TGCGTTATCA AAAAGAAATC 540ATCAAAAACA ACCGACTCAA TATTTTCCCC AAATGGGCGA ACGCTGAGCA AACGGAGTTT 600TATTACACGC AGTATGGCGA AAAAACGCCC ATGATTTTAA AATACAACAT TCAAAAAGCC 660ACTCATGAGA ATATCGCTAG CTCTCAAGGA ATGGCTGTGG TCTCTAGCGT GAGTTCTGAT 720GGCTCTAAAA TTTTAATGTC TTTAGCCCCT GATGGCCAAC CGGATGTTTA TTTGTATGAC 780ACGCATAAAA AAACTAAAAC CAAAATAACG CGCTATCCGG GGATAGATGT TTCAGGCGTG 840TTTTTAGAAG ATGACAAGTC TATGGCTTTT GTTTCAGATA GATCCGGTTA TCCTAACATC 900TATATGAAGA AATTGGGGTT AAAAGAGAGC GCGGAGCAAC TCCTTTATGA AGGAAGAAGC 960AATGAATCCA TTGACGCCTA TAAGGATAGT ATCGTGTATG TGAGCCGAGA AAACCTTAAT 1020GAATTTGGCA AAACGGTGTT TAATTTGAAT TTGATCGCTC TAAACAGCAA GTATATCCGC 1080AGGCTTACCG TGAATGGCTC TAACCAGATG CCTAGGTTTT CTATGGATGG GAGAAATATC 1140ATGTATATCA AAAAGACATC TCAAGAATAC GCCATGGGGC TTATTTTGCT AGACTATAAT 1200CAGAGTTTTT TATTCCCTTT AAAGAATGTG AAAATACAAG CCTTTGATTG GTAA 1254(2) SEQ ID NO 1007 information

Sequence properties:

(A) length: 660 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...660

(xi) sequence representation: SEQ ID NO:1007: GTGAATAAAA AGCACCGCTT GGCTTTTTTA GGGCTAATTG TTGGGGTTCT ATTCTTCTTT 60AGCGCGTGCC AACACCGCCT GCACATGGGG TATTATTCAG AAGTTACAGG GGATTATTTG 120TTCAATTATA ATTCCACTAT CGTGGTGGCT TATGACAGAA GCGATGCGAT GACTTCTTAT 180TATATCAATG TGATTGTTTA TGAATTGCAA AAATTAGGCT TTTATAATGT CTTCACGCAA 240GCGGAATTCC CGCTAGATAA AGCAAAAAAT GTGATCTATG TGCGTATTGT CCGTAATATC 300TCGGCTGTGC CGTTTTATCA ATACAATTAC CAACTGATCG ATCAAGTCAA TAAGCCTTGT 360TATTTTCTTG GGGGGCAGTT TTATTGCTCC CAAACCCCTA CGGATTACTA CGCTATCAAT 420GGCTTTAGCG AGCAAATTTT GATGAGCGCT AATTCGCATT TTATTTTGGA TTGGTATGAT 480GTGGTGCTGC AAAAACGGGT TTTATATGTG GATGGGAGCG TGAGCGGGAG GACTTGTGGC 540TATCAGATGC TTTATAGAGA TTTGATTAAA AGCACGATCA AACGCATTGA TTTTAACCGC 600CCTGAACGCT ACTACTACAA TTTAAGACTG CCCCTTTATC AGCCATGTTA TAGGCAATGA 660(2) SEQ ID NO:1008 information

Sequence properties:

(A) length: 1251 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1251

(xi) sequence representation: SEQ ID NO 1008 ATGCAATATA AGAAAAATAA GAAAAGATAT TATCATTTAG CGTTAGGGAT CCTTTTTTGT 60AATGGTCTGT CTTTGAAAGC TTTAGAAATT GCCGTCAAAC CCTTTGGCTA TCTGGGGCTA 120TTGTATAATC AAGGGACGCA AAAAAACCCT CACAGCTATG TGGGGGCTTT AGCGCGTCTT 180GGGGTGGATT TTTCTTATAG CAATGGGTGG TCGTTTGGTA TTGGGGCTAT TGGGGCTTGG 240AATATTTATA ACAAACAGCG TTTGGCTAAC CTTTACATCA GTCTAGGGAA TTTTTTTGGT 300AACCCTAACA ACGTTAAGCC TTATTTGAGC GCCGGCGATG TTTCTGATGC GTATCTTCAA 360TACGCTAACC AGCGTTTTAA AATCGCTTTA GGGCGTTTTA ATACCGATTT TGTGGATTTT 420GATTGGATAG GGGGCAATAT TCAAGGGGTC TCTGTGGCTT TCAAGCAAAA TTCCATGCGT 480TATTTTGGGA TTTTTATGGA TAGCATGCTT TATAATGGGC ATCAAATCAA TAAAGAGCAA 540GGGAATCGGA TCGCCACTTC CCTAAACGCT CTAGCGTCTT ATGATCCTGT GTCTAAACGC 600TTGTATGTAG GGGGGGAAGT GTTTGTTTTG GGCGCAGAAT ACAAAAATAA AAATTTGATA 660TTCGTTCCTT TTATTTTAAC GGACACCCGC TTGCCTTTGC CCACCCAAAA TGTTTTAGTG 720CAAGTGGGGG GTAAGTTGGA GTATGACGCT TCTTTAGCTA AGGGTTTCAC TTCGCGCACT 780CTAGTGCATG GCATGTATCA ATACGGCAAC ACCGATATTA CTACAAGCGC TAAAAATGCC 840GGCTTGTTTT TGATCGATCA AACTTTCAAA TATAAAATTT TTAATTTTGG AACGGGTTTT 900TATATCGTTC CGGCAAGGAA CAATAAGGGC TATCTATGGA CTTTTAATGA CAGGACTAAA 960TTCTATGGCC GTGGGATCAA CGCGCCCGGC GTACCAGCGA TTTATTTTGC TAACTCCAGC 1020ATTTCAGGCT ATGTTTTTTT AGGGCTTAAG ACTAAAAGGG TGCGTTTAGA TGCGATGGTG 1080GCTTTTGGGG ATTATCAAGA ATATTCTTTG ATGAGCAGTT TTAGGGTTTG GACTTATAGG 1140GATTTGTCTT TTGATATGGG TGGGGGGTAT GTGTATGCTT ATAATTCTAA AGCCACGAGA 1200AAAAGCCTTG GAGATAGCTC TTTTGTCTTT TTTGGGAAGT TTTTGTTTTA A1251 (2) SEQ ID NO 1009 information

Sequence properties:

(A) length: 2007 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2007

(xi) sequence representation: SEQ ID NO 1009: ATGGTGAAAA ACACCAAAGG CATTCAACAG CTTTCAGAGA ATTATGAAAA GTTGAACAAT 60CTTTTAAATA ATTACAACAC CCTAAACACT CTTGTAAAGC TGTCCTCCGA TCCGAGTGCT 120GTCAACGACG CAAGGGATAA TCTAGGCTCA AGCACTAGGA ATTTGCTAGA TGTCAAAGCC 180AATTCCCCCG CCTATCAAGC GGTGCTTTTA GCATTGAACG CTGCAGTGGG CTTGTGGCAA 240GTTACAAGCT ATGCCTTTAC CGCTTGTGGT CCTGGTAGCA ATGAGAACGC GAATGGAGGT 300ATCCAAACCT TTAATAATGT GCCAGGACAA AACACGACGA CCATCACTTG TAATTCGTAT 360TATGAGCCAG GACATGGCGG GCCAATATCC ACTAAAAATT ATGCGATCAT CAACAAGGCT 420TATCAAATCA TTCAAAAGGC TTTGACAGCC AATGGAGAAG GGATCCCAGT TTTAAGCAAC 480ACCACTACAA AACTTGATTT CACTATCAAT GGAGACAAAA GAACGGGTGG CGAACCAAAT 540AAAAAATTAG TATACCCATG GAGTCATGGG AAAGCTATTT CAACCTCGTG GAATGCAACC 600ATAACAGCAC CAACAACAGA AAATATCAAT ACAACCAATA GCGCTCAAGA GCTTTTAAAA 660CAAGCGAGCA TCATTATCAC TACCCTGAAT AGTGCATGCC CAAACTTCCA AAATGGTGGT 720AGCGGTTATT GGGCAGGGAT AAGTGGCAAT GGGACAATGT GTGGGATGTT TAAGAATGAA 780ATCAGCGCTA TCCAAGGCAT GATCGCTAAC GCGCAAGAAG CTGTCGCGCA AGCCAAAATC 840GTTAGTGAAA ACACGCAAAA TCAAAACAGC CTAGACGCTG GAAAACCATT CAACCCCTAC 900ACAGACGCTA GTTTTGCTGA AAGCATGCTC AAAAACGCGC AAGCCCAAGC GGAGATTTTA 960AACCAAGCCG AACAAGTGGT GAAAAACTTT GAAAAAATCC CTACAGCCTT TGTAAATGAC 1020TCTTTAGGGG TGTGTTATGA AGTGCAAGGA GGTGAGCGTC GTGGCACCAATCCGGGTCAG 1080ACGACTTCTA ACACTTGGGG GGCAGGCTGT GCGTATGTAG GACAAACGAT AACAAATCTT 1140AAAAACAGCA TCGCCCATTT TGGCACTCAA GAGCAGCAGA TACAGCAAGC CGAAAACATC 1200GCTGACACTC TGGTGAATTT CAAATCTAGA TACAGCGAAT TGGGCAACAC TTATAACAGC 1260ATCACCACTG CGCTCTCTAA TATCCCTAAC GCGCAAAGCT TGCAAAATGC GGTGAGTAAA 1320AAGAATAACC CCTATAGCCC GCAAGGCATA GACACCAATT ACTACCTCAA TCAAAACTCT 1380TACAACCAAA TCCAAACCAT CAACCAAGAA CTCGGGCGTA ACCCCTTTAG GAAAGTGGGG 1440ATTGTTAGTT CTCAAACCAA TAATGGCGCG ATGAATGGGA TCGGTATTCA GGTGGGTTAC 1500AAACAATTCT TTGGCCAAAA AAGAAAATGG GGCGCTAGGT ATTACGGCTT TTTTGATTAC 1560AACCATGCGT TCATTAAATC CAGCTTCTTC AACTCGGCTT CTGACGTGTG GACTTATGGC 1620TTTGGAGCGG ACGCTCTTTA TAATTTCATC AACGATAAAG CCACCAATTT CTTAGGCAAA 1680AACAACAAGC TTTCTGTGGG GCTTTTTGGG GGTATTGCAT TAGCCGGGAC TTCATGGCTT 1740AATTCTGAGT ATGTGAATTT AGCCACCATG AATAACGTCT ATAACGCTAA AATGAACGTG 1800GCGAATTTCC AATTCTTATT CAACATGGGA GTGAGGATGA ATTTAGCCAG GCCTAAGAAA 1860AAAGACAGCG ATCATGCGGC TCAGCATGGG ATTGAGTTAG GGCTTAAAAT CCCCACCATC 1920AACACGAACT ACTACTCCTT TATGGGGGCT GAACTCAAAT ACCGAAGGCT CTATAGCGTG 1980TATTTGAATT ACGTGTTCGC TTACTAA 2007(2) SEQ ID NO 1010 information

Sequence properties:

(A) length: 1029 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1029

(xi) sequence representation: SEQ ID NO 1010: TTGACTAAAA AATTCATGTC TTGGATGGTG GTTATCGGGG CTTTAATTTG CGTGCTTTTA 60GGGGTGTTTA TCTTCTTCAC TAGCATGTCG GTTAAAAAAT CTTTAACCGC TTATCTTAAC 120GCTTATTTAG AGCAACGCCC AAATATCGAG GGCATGGGGA TTATAGGAGT TCCTTTTAAA 180TGCGAAGGGT TTTTTAAAAT CGCATGCGTT TCTAAAGAAC TTCGTTTTTT AGATCCTCAA 240AACTCCCCTA TTATGGATTT TAAAAATTTA AAGATCAAGC TCCATTCTTT AGATAAAAGC 300TCTCTTACCC TTTCTATCCA TTCTCAAATC CAATCCCCTA TTTTAGAACA ATCCATTCAG 360CAAAAAATCA GCCAAATCCC CTTAAAAAAC TTGAATGCCT TATTGGAAAA ATTCAAACCC 420ACGCGCTTGA ATTGCTCTTT AACATTCAAC GCTTTAGATG AAAAAACCTT AAACGATAAT 480TTAAAATGCG ATTTGACTAA TGCAGAGAAT ATCCTTGCTT ACACTTTTTT TCAAGAAGGT 540TTAATGGAGG CGCAAGAAAA TCTCTCCCTT AAAAATATTT TTAAAACCTT GAGTTCTAAA 600GACGCTAAAG CCATAGAAGA GTTGCAAGAC AAACTGCGTT TTTTAGCGCC AAAGTTGAGT 660GTTTCTATCC AAGCACGCCA TTTTAAAAAC GTTTTAGAGT CCTTTTACCA ACAAAATAAA 720GAGAGTTTGG GCTTTTTTTC CCCTTATTTT AGTTTGCGTT CTCAAACCCC TAGCGTCTCT 780TATGAAAGCG CGTTAGCTTC TTTAGAAAAC TATTTTATGG CCTTGTTCCA ATCCCATTTT 840AAAGACGATA CCGCGCTCCA ACAGAATTTT AAAGGATTGT TGCAAGCCTT TGTTTCTATG 900GCTAAAGACA AACGATCTCA AATCGTTCTT AACGCCCAAG CTAAAGACAA CACCAAGCTG 960ACTTTTAACG CCTTGTTAGA AAGCCTAAGC GTGAATTTCT TTCAATCTTA CAAAATAAGC 1020CATGAGTGA 1029(2) SEQ ID NO 1011 information

Sequence properties:

(A) length: 882 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _feature

(B) Position: 1...882

(xi) sequence representation: 1011: ATGAGATTGT TGTTCTTGTT ACTGAGCGCT ACTTTGATGT TACTGGCTGA AGAAAAAATA 60CCTTTAAGCG ATGACGCCCC CATTAAATTG GTTCATTGGC AAAATGCGCT AAAAGAAGTC 120CAACCCGATT CAAACGCTCC GGCAACGCCA CCTATAAAGG CCGTGCAAAC CACGCTCACT 180TTTGAAACGC CTTTTAATAA AACGCCTAAA ATCATGGAGG TTGAAGGGCA AAAAGTCATC 240GTGTTAAAAA ACGCTCAATT GGATTCTAAA AAAACGATGG ATTTTAAAGA AGCCTCTTTG 300AATGCCTTAG AAATGTTTTC CTACCAAAAT GACATCTACC TCTTGTCTAA AAAAGCTAAA 360GCGGGATTAG AAATCCAAGC TTCAAGCAGC AAGGATAAAA AGCAACTCCG CTTTCTTTTT 420TTACCCAAAG GTTTTCATTT AGCCCCACCG CCTAGCCTGA AAGAAAAATC TCAGCATGCC 480AATCTCGCAA GCCAAGATGA AAAAGAGCGA GCCAAAAGCC CCTCAAACGC TCTAGAGTTA 540AAACCCCCAC TGGATTTAAG CCATGCTTAC AAGGGGTTAG CGGTTATTGC TGTCTTACTC 600 AATCTCGCAA GCCAAGATGA AAAAGAGCGA GCCAAAAGCC CCTCAAACGC TCTAGAGTTA 600TTAATATTGT ATGTAATCAA AAAAAAAATT GTTCCTACAC CAGGGTCTTT TTTAAAAAAA 660GATTTGAAGC TAGACATTAG CGTTTTGGGT CGTGTTGATG CGAACCATAA AATCATCTCA 720ATAGAAACCA ATAAGGAGCG TTACTTGGTC TTACTAAGCG ACAAATACGG CCTGCTTTTA 780GACAAAATAA GCCCAAAAAC ATCTAAAGAA GAACTGATTA AAGAAGCTGA AAATAAGATA 840AAGAATTCAA AATTAGGAAA TTTATATGCC GGAAAATTCT AA 882(2) SEQ ID NO 1012 information

Sequence properties:

(A) length: 861 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...861

(xi) sequence representation: SEQ ID NO 1012: ATGCTTAGAA ATCAATTTCG TATCGTGTTT GTCTCTTGTA TTGTCGCTAG CAGTTTGCAA 60GCTCAAGAAA ATACCCACAC TTTGGGTAAG GTAACCACTA AGGGTGAAAG GACTTTTGAA 120TACAACAATA AAATGTATAT TGACAGGAAA GAGCTCCAAC AACGCCAAAG CAACCAAATC 180CGTGATATTT TTAGGACTAG GGCGGATGTG AATGTGGCCA GTGGGGGCTT AATGGCGCAA 240AAAATCTATG TTAGGGGGAT TGAGAGCCGT CTCTTAAGGG TAACGATAGA TGGCGTCGCT 300CAAAATGGTA ACATTTTCCA CCATGACGCT AACACCGTGA TCGATCCCAA CATGATTAAA 360GAAGTGGAAG TGATTAAGGG GGCAGCGAAC GCTTCAGCAG GTCCAGGCGC GGTTGCGGGT 420AAATTGTCTT TCACCACGAT TGACGCTAAC GACTTTTTAA GAAAGAATCA AACTTATGGC 480GCTAAAGCGG AAGCAGCCTT TTACACTAAC TTTGGATACC GCATGAACGC CACTGCAGCC 540TATCGGGGGA AAAACTGGGA CATCCTAGCC TATTACAACC ATCAAAATAT TTTTTACTAC 600AGAGACGGGA ATAACGCTTT TAGGAGTCTC TTCCACCCTA ACTACGATTT ACAAGATCCA 660AGCAATAGCG AAATGAGCGT AGGGACTCCT AGTGAAGTCA ATAGCGTTTT AGCTAAAATT 720AATGGCTATA TCAACGAAAC CGATAGCATT AGCGTGAGCT ACAACCTCAC ACGAGACAAT 780TCTACAAGGC TTTTACGCCC TAACACCACT TCAGCCCTCT CCAAAGCCAA TGACCAGGAA 840GCCAGCCAGC CCCCTTTGTG A861 (2) information of SEQ ID NO 1013

Sequence properties:

(A) length: 1026 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1026

(xi) sequence representation: SEQ ID NO 1013: ATGAAACGGC TTTTATTGTT AGCCTTGGCC CTCTTTTTTA GCCTCTCATG CACTAACGCT 60CAAGAAATTA AAGAAACTCA AGAGACTAAA AAAACTAAAG AAACTAAAAG CCAAACCCGT 120TTTAACATTT CCACCACTAA GGTCATAGAA AAAGAATTTT CTCAAAGCCG GCGCTATTAC 180GCGCTTTTAG AGCCTAATGA AGCGCTGATT TTTTCTCAAA CCCTGCGTTT TGATGGCTAT 240GTGGAAAAGC TTTATGCGAA TAAAACCTAT ACCCCCATTA AAAAGGGCGA TAGGCTATTG 300AGCGTGTATT CCCCTGAATT AGCGGGCGTT CAAAGCGAGC TGTTATCGTC ATTGAAATTC 360AACCAGCAAG TGGGAGCGAT TAAAGAAAAA TTAAAACTAC TAGGGCTAGA AAACTTTAGC 420ATTGAAAAAA TCATCAGCAG CCATAAAGTC CAAAATGAAA TCACTATTTA CTCTCGTTTC 480AACGGCGTTA TTTTTAAAAA AAGCCCGGAT CTCAATGAGG GGAGTTTCAT TAAAAAAGGG 540CAAGAGCTTT TCAAAATCAT AGATTTAAGC CGATTGTGGG CGCTTGTTAA AGTCAATCAA 600GAGGATTTAG AATTTTTAAA AAACACGCAT CAAGCGATTT TGTTCGTAGA GGGGGTTAAA 660GGCAAGCAAG CAATCACGCT TGAAAACATC AACCCCATCA TAAATGCGCA AGATAAAATG 720CTAGAAGCGC GCTTCAATGT GCCTAATCTT AAATTGCTTT ATTACCCTAA CATGTTCGCT 780CAAGTAGAAA TCTTTCACAA ACCCCAAAAA ATGAAGATCT TGCCTAAAGA AGCGGTTTTG 840ATTAAGGGGG GGAAAGCTAT CGTGTTTAAA AAAGATGATT TTGGCTTAAG CCCGTTAGAA 900ATTAAAGCCG TCCGCTTGAG CGATGGGAGT TATGAAATTT TAGAGGGTTT AAAAGCGGGC 960GAAGAAGTCG CTAATAACGC TTTATTCGTG CTAGACGCTG ACGCTCAAAA CAATGGGGAT 1020TAT TGA 1026(2) SEQ ID NO 1014 information

Sequence properties:

(A) length: 1392 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1392

(xi) sequence representation: SEQ ID NO 1014: ATGGCTTTTT GCGCTCGCCA AAAGCCTCTA AAGGAAATCA TGCGTTTTTT TATTTTATTT 60TTTATGGGTA TGCTTGGCGT TGGTTTTTCT CAAACCGAGT TGGATTTAAA GGATTTAGAA 120AAAAAGCCCG CCGGGATCGT TAGGGATTAT TATTTATGGC GTTATATTAG CGATAAAAAA 180ACGAGTTTAG AAAACGCTAA AAAAGCCTAT GAATTGACTC AAAATAAAAA CAGCGCCCTA 240CAAAAAGCCA TGCAAGAAAA AGGCGTAGAA AATTCAGATA AAAGCCCTGA TGCCAAAATG 300CCTGAAGATA TTTATTGCAA GCAAATTACC TTAGAAAGCA TGTTAGAAAC AACAGACGCT 360TTCCAAGCGA GTTGTATCGC TATCGCTTTA AAATCAAAAA TCAGAGATTT TGATAAAATC 420CCCATTCAAA CCTTTAAACC TTTACAAGAA AAAATCAAAG AGGCTTACCC CATTCTTTAT 480GAAGAATTAG AAATCTTGCA AAGTAAGAAC GTGAGCGCTT CTTTGTTTAA GGCTAACGCG 540CAAGTGTTTA GCGCGCTCTT TAATCATTTG AGTTATGAAA AAAAGCTCCA AATTTTTGAA 600AAGCATATCC CGATTAAAGA GTTAAACCGC CTTTTAGATG AAGATTACCC GGCGTTTAAC 660CGCTTGATCT ATCAAGTCAT CTTAGATCCT AAATTGGATC ATTTTAAAGA CGCTCTCGCT 720AAAAGTAACG CCACCCAAAG CAACGCGCAA ACCTTTTTTA TTCTAGGAAT CAATGAAATC 780TTGCACAAAA AAACTTCTAA AGCGCTCAAG TATTTTGAAC GCTCAGAAGC GGTTGTCAAG 840GACGATGATT TTTCAAAAGA CAGAGCGATT TTTTGGCAGT ATTTAGCCTC TAAAAAGAAA 900AAAACTTTGG AGCACCTTTC ACAAAGCCCA GCCCTAAACC TCTATAGTCT TTATGCGAGC 960CGCAAACTCA AAACCACGCC CAGTTATCGC ATCATTTCTC ATATCCAAAA TTTAAGCCAA 1020GAGAACCCTC CTTTTAACAC TTACGATCCT TTTTCGTGGC AAATTTTTAA GGAAAAAACT 1080TTGAGTTTGA AAGATGAGGG CGCGTTTAAT GCGATGCTAA AAAGCCTGTA TTATGAAAAA 1140AGCGCTCCTG AATTGACTTA CCTTTTAAGC CAACGCAATA AAGACAAGAT TTATTATTAT 1200TTATCCCCTT ATGAGGGCAT TATTGAGTGG CAAAATACAG ATGAAAGGGC TATGGCGTAT 1260GCGATCGCTA GGCAAGAAAG CTTTTTGCTC CCGGCTTTAA TCTCTCGCTC CTTCGCTCTA 1320GGGCTTATGC AGATCATGCC TTTTAATGTA GGGCCTTTCG CTAAAGCCTT GGCATGGATA 1380ATGTTGATCT AA 1392 (SEQ ID NO:1015 information)

Sequence properties:

(A) length: 1125 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1125

(xi) sequence representation: SEQ ID NO:1015: ATGCCAAAAA GAATGAAGTG TTTTAGTCAA AAATGGTTGG TTTTTTTTGT TACCCATTGG 60CTTTTGTTGG CTTCTTTAAG TCATGCGAAG ATGGCTTTTG AATCCAATAT TGACACCAAA 120GCGTTAGAGG CTTTTGGGGT CAATGCGAGC TTTTTATCCC AAATGCCAGG CGCTTTAAAA 180AAGGTGAATA AGGAAGACGA ATGGAAAAAG TTAGTCAAAA GATTTGACGT GAATTACCAA 240TTCATCCCTA TCATTAAAAA CATGCTCATA GGAGCGAGCG TGCCGCAAGA ATTTTTGTTT 300TTAGCCATGG CCGAGTCTAA GTTTTCATCA AGGGCTTATA GCAGGAAAAA AGCGGTAGGG 360ATTTGGCAAT TCATGCCAAG CACGGCCAAA GAGTTAGGGC TTAAGGTCAA TCATTACATT 420GATGAAAGAA GAGATCCCAT TAAAAGCACT CAAGCGGCGA TCGCTTATTT GAAACGGCTC 480TACAAGCAAA CCGGTGAGTG GTATTTGGTC GCTATGGCGT ATAATTACGG CTTACGCAAG 540GTTCAAAACG CTATTAAAGC CGCCGGCACT TCAGACATTA AAGTCTTGCT AGATGAAGAT 600AAAAAATACC TCCCTAAAGA AACACGAGAG TATATCCGCT CCATTCTAAG CCTGGCGTTG 660AAATTCAACA GCCTAGACAA TCTCAAAGAT AAAGAGTATT TGCTCAATCG TGGGGCGAGG 720GTGAGTTTAG TGGGCGTCCC GTTTAAAAGA CACACTTCTT TAGTCCAGGT GGCCAAAAAT 780TTGAATTTGA GTTTAGAAAC CTTAAAATCT TACAACCACC AATTCCGCTA TAACATTCTG 840CCCTCTAAAG ACCCCACCTA CACCATTTAT ATCCCTTATG AAAAACTCGC CCTTTTCAAA 900CAACGCCAAC TCAAACAAAA TAAAAACGCT CAAGCTAATC CTAAAAGCCC TTTCATCACC 960CATGTGGTCT TGCCTAAAGA AACCTTATCT TCTATCGCTA AACGCTATCA AGTCAGCATT 1020TCCAGTATCC AATTAGCCAA TAACCTCAAA GATTCTAATA TCTTTATCCA CCAGCGCTTA 1080ATCATCCCCA CTAACAAAAA ATTACTCGCT ACAAGGGAAT TTTAA 1125(2) SEQ ID NO:1016 information.

Sequence properties:

(A) length: 1002 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: microsfecture

(B) Position: 1...1002

(xi) sequence representation: SEQ ID NO:1016: ATGCTAATCG CTCGCTTTAA AAAAGCTTTA ATTTCCTATT CTTTAGGGGT TCTTCTTGTT 60: 60TCATCGTTAT TAGGCGTGGC TAACGCTTCT AATCAAGAGA TCCAAGTCAA GGATTATTTT 120GGGGAGCAAA CCATAAAGCT TCCTGTTTCT AAAATAATCT ACTTGGGCAG CTTTGCAGAA 180GTGCCTGCCA TGTTCAATAC TTGGGATAGG GTCGTGGGCA TTTCGGATTA CGCTTTTAAA 240TCTGATATTG TTAAAGCCAC TCTCAAAGAT CCTGAACGCA TTAAACCCAT GAGCAGTGAT 300CATGTGGCGG CGTTGAATGT GGAATTATTA AAAAAGCTTA GCCCTGATCT TGTGGTAACC 360TTTGTGGGTA ACCCTAAAGC GGTAGAGCAT GCGAAAAAAT TTGGGATTTC ATTCCTTTCT 420TTCCAAGAAA AAACCATTGT AGAGGTCATG GAAGATATTG ACGCTCAAGC TAAGGCCTTA 480GAAGTTGACG CTTCTAAAAA ATTGGCTAAA ATGCAAGAAA CTTTGGATTT TATCAAAGAG 540CGTTTGAAAA ATGTCAAAAA GAAAAAGGGG GTGGAGCTTT TCCATAAAGC CAATAAAATC 600AGCGGCCATC AAGCCCTTGA TTCAGATATT TTAGAAAAAG GGGGCATAGA CAATTTTGGC 660TTGAAATACG TCAAGTTTGG GCGCGCTGAC ATTAGTGTGG AAAAAATCGT TAAAGAAAAC 720CCTGAGATTA TTTTTATTTG GTGGATAAGC CCGCTTAGCC CTGAAGACGT GTTGAACAAC 780CCTAAATTTT CCACTATCAA AGCCATTAAA AACAAGCAAG TCTATAAGCT CCCCACAATG 840GATATTGGCG GACCTAGAGC CCCACTCATT AGTCTTTTTA TCGCTTTAAA AGCCCACCCT 900GAAGCGTTTA AGGGCGTGGA TATTAATGCG ATAATCAAAG ATTACTATAA AGTGGTCTTT 960GATTTGAATG ACGCGGAAGT TGAACCCTTT TTGTGGCACT GA 1002(2) SEQ ID NO:1017 information

Sequence properties:

(A) length: 1602 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1602

(xi) sequence representation: SEQ ID NO 1017: ATGGAAATTA GAAACATCAA AGAGTTTGAA AAAGCTTCCA AAAAACTCCA AAAAGACACT 60TTAAAGATCG CTCTCGCTCT TTTGTTCCTC ATTGGCGCCG CTTTGCTCGC TCTCATTTTT 120GGGCAGGCTA ATTCTAAGGG ATTGTTGCTC ATCTTTGCGG CCGTGATTGG GGGGTATATG 180GCGATGAATA TTGGCGCGAA CGATGTGTCT AATAATGTCG GCCCTGCCGT AGGCTCTAAA 240GCCATTAGCA TGGGTGGGGC GATTTTGATC GCTGCGGTTT GTGAAATGCT AGGAGCGATC 300ATTGCTGGGG GGGAAGTGGT TTCTACGATT AAGGGCCGTA TCGTTTCGCC TGAATTTATT 360AACGATGCGC ATGTTTTCAT TAATGTCATG TTGGCTAGCC TTTTGAGTGG GGCGTTATGG 420TTGCATGTAG CCACTTTAAT AGGCGCTCCC GTTTCCACTT CGCACTCCGT AGTGGGAGGG 480ATTATGGGGG CTGGAATGGC AGCAGCTGGA ATGTCTGCTA TCAATTGGCA TTTTTTATCC 540GGCATTGTGG CTAGTTGGGT AATCTCGCCT TTAATGGGGG CTTTGATAGC CATGTTTTTT 600TTAATGCTCA TTAAAAAGAC TATCGCTTAT AAAGAAGATA AAAAGAGCGC GGCTTTAAAG 660GTCGTGCCTT ATTTGGTGGC GTTGATGAGC TTAGCCTTTA GCTGGTATTT GATCGTGAAG 720GTTTTAAAAC GCCTCTATGC GGTGGGTTTT GAAATCCAGC TCGCTTGCGG TTGTGTCCTT 780GCGCTTTTGATTTTTATCCT TTTTAAAAGA TTTGTGTTAA AAAAAGCCCC GCAATTAGAA 840AATAGCCACG AAAGCGTCAA TGAGCTTTTT AATGTCCCTT TGATTTTTGC CGCCGCGCTT 900TTAAGCTTTG CGCATGGGGC TAATGATGTA GCTAACGCTA TCGGTCCTTT AGCCGCAATC 960AGTCAAACTT TAGAAGATGC GAGCAGCCCT ATGGGGAGTA CTTTAAACTC TGTGCCGTTG 1020TGGATTATGG TAGTAGGGGC AGCTGGGATC GCTTTAGGCT TGAGCTTGTA TGGGCCAAAG 1080CTCATTAAAA CGGTGGGGTC TGAAATCACA GAATTAGACA AAATGCAAGC TTTTTGCATC 1140GCGCTTTCAG CGGTCATCAC CGTGCTTTTA GCCTCTCAAT TAGGCTTACC GGTAAGCTCT 1200ACGCATATTG TGGTGGGCGC GGTGTTTGGG GTGGGCTTTT TAAGGGAGCG TTTGAGGGAG 1260CAATCCAGAA GGCGTTTTGC TAGAATCAGA GACAACATTG TAGCGGCGCA CTTTGGGGAA 1320GATTTAGAAG AAATTGAAGG CTTTTTAGAG CGCTTTGATA AAGCCAATTT GAAAGAAAAA 1380TCGCTCATGC TAGAGAGCTT GAAAAAAAGC AAGAACACCG CTATCGCTTT GGAATTGAAA 1440AAGAAAGAAA AAAAGTCGCT TAAAAAAGTG TATAAAGAAG AAGTGATCAA ACGCTCCATT 1500TTGAAAAAGA TTGTTACCGC TTGGTTGGTA ACCGTGCCGG TTTCTGCGCT TTTAGGGGCG 1560CTTCTTTTTG TAGCTCTTGG TTTTATAGAA AAGTATTTCT AG 1602(2) SEQ ID NO 1018 information

Sequence properties:

(A) length: 990 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...990

(xi) sequence representation: SEQ ID NO 1018: ATGTCAAATA GCATGTTGGA TAAAAATAAA GCGATTCTTA CAGGGGGTGG GGCTTTATTG 60TTAGGGCTAA TCGTGCTTTT TTATTTGGCT TATCGCCCTA AGGCTGAAGT GTTGCAAGGG 120TTTTTAGAGG CTAGGGAATA CAGCGTGAGC TCTAAAGTCC CTGGCCGCAT TGAAAAGGTG 180TTTGTTAAAA AAGGCGATCG CATTAAAAAG GGCGATTTAG TTTTTAGCAT TTCTAGCCCT 240GAATTAGAAG CCAAGCTCGC TCAAGCTGAA GCCGGGCATA AAGCCGCTAA AGCCGTTAGC 300GATGAAGTGA AAAGAGGCTC AAGAGATGAA ACGATCAATT CTGCGAGGGA CGTTTGGCAA 360GCGGCAAAAT CCCAAGCGAA TTTGGCTAAA GAGACTTATA AGCGCGTTCA AGATTTGTAT 420GACAATGGCG TGGCGAGTTT GCAAAAGCGC GATGAAGCCT ATGCGGCTTA TGAAAGCACC 480AAATACAACG AGAGCGCGGC TTACCAAAAG TATAAAATGG CTTTAGGGGG GGCGAGTTCT 540GAAAGCAAGA TTGCCGCTAA GGCTAAAGAG AGCGCGGCTT TAGGGCAAGT GAATGAAGTG 600GAATCCTACT TAAAAGACGT CAAAGCCCTA GCCCCTATTG ATGGGGAAGT GAGTAACGTG 660CTTTTAAGCG GTGGCGAGCT TAGCCCTAAG GGCTTTCCTG TGGTGCTCAT GATAGATTTA 720AAGGATAGTT GGTTAAAAAT CAGCGTGCCT GAAAAGTATT TGAACGAGTT TAAAGTGGGT 780AAGGAATTTG AAGGCTATAT CCCAGCGTTG AAAAGAAGCG CGAAATTCAG GGTCAAATAT 840TTGAGCGTGA TGGGGGATTT TGCGACCTGG AAAGCGACGA ATAATTCCAA CACTTACGAC 900ATGAAAAGCT ATGAAGTGGA GGCCATACCC TTAGAAGAGT TGGAAAACTT TAGGGTGGGG 960ATGAGCGTGT TGGTTACCAT TAAACCTTAA 990(2) SEQ ID NO 1019 information

Sequence properties:

(A) length: 879 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...879

(xi) sequence representation: SEQ ID NO 1019: AGACTGGAAT CACCGCTACA CTCAGGCTTT AGCCCTAGCG CGGCCCTTGT GATCAGCCCC 60ATTGAGCCTT TATCTCTAAA AATCACTTAT TCTCAAGTTA CAAGGGGGGT TATGCCAGGA 120GATGGCGTGT ACATGCGTCA AAACGATTTA CGATACGCTA AAAATATCAA GCCTGAAGTG 180GGCTCTAACG CTGAATTTAA TATTGACTAT TCAAGCCAGT ATTTTAGCGG GAGGGCTGCG 240GCGTTCTATC AAGCTTTGGA TAATTTCATC TCACAATACG CGCAACGCTT GATCGTAACC 300AATTTGAGTC AAGCGATTCG CATTTATGGC TATGAAGTGG GTGGGACTTT TAGATACAAG 360GGCGTGAGTT TGAATGTGGG GATCTCGCGC ACTTGGCCCA CCACTAGGGG GTATTTAATG 420GCGGACAGCT ATGAGCTTGC CGCAAGCACC GGTAATGTTT TTATCATTAA ATTGGATTAC 480ACCATTCCAA AAACAGGGAT CAATCTTGCA TGGCTTAGCC GCTTTGTTAC CGGTTTGGAT 540TATTGCGGGT TTGATATTTA CTTGCCTGAT TATGGGACAG CTGAAAAACC CAAAACCCCT 600ACCGATTTAG CCAAATGCGG ATCCCAATTG GGGTTAGTGC ATATGCACAA ACCGGGCTAT 660GGCGTGAGTA ATTTTTATAT CAATTGGAGC CCTAAAACCA AAAGCCACTG GAAGGGTTTG 720CTGCTTTCAG CCGTGTTTAA TAATGTTTTC AACAAATTCT ATGTGGATCA AACAAGCCCC 780TATGTCATGA GCCCGGATAT GCCAGGCACT GACGCTATTA AAAGAGCGAT CGCAGAGCCT 840GGGTTTAATG CGCGTTTTGA AGTGGCTTAC AAATGGTAG 879(2) SEQ ID NO 1020 information

Sequence properties:

(A) length: 1455 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1455

(xi) sequence representation: 1020: ATGGCTAAAA TCACAACCGT GATTGACATA GGCTCTAATT CAGTGCGTTT GGCTGTCTTT 60AAAAAGACGA GCCAGTTTGG GTTTTACTTG CTTTTTGAGA CTAAGTCCAA GGTTAGGATT 120TCAGAGGGCT GTTATGCGTT TAAAGGGGTT TTACAAGAAA TCCCCATGCA ACGAGCCGTT 180AAAGCCTTGA GCGAATTTAA AGAAATCGCC CTCAAATACA AAAGCAAAAA AATCCTGTGC 240GTGGCGACCT CAGCGGTGCG CGATGCCCCT AATCGGTTAG AGTTTGTAGC GAGGGTGAAA 300AAGGCTTGCG GTTTGCAAAT CAAAATCATT GATGGGCAAA AAGAAGCGCT CTATGGTGGG 360ATCGCGTGCG CGAATTTGCT GCATAAAAAT TCAGGGATCA CGATAGACAT TGGAGGGGGT 420AGCACCGAGT GCGCGTTGAT TGAGAAAGGT AAGATTAAGG ACTTAATCTC GCTTGATGTC 480GGGACGATTC GCATTAAAGA AATGTTTCTA GACAAAGACT TAGATGTCAA ATTGGCTAAA 540GCCTTTATCC AAAAAGAGGT CTCTAAACTG CCTTTTAAGC ATAAAAACGC CTTTGGGGTG 600GGGGGGACGA TCAGAGCCTT GAGTAAGGTG CTGATGAAAC GCTTTGATTA CCCTATAGAT 660TCTTTGCATG GCTATGAAAT AGATGCGCAT AAAAATTTAG CGTTCATTGA AAAAATCGTC 720ATGCTCAAAG AAGACAAATT ACGGCTTTTA GGGGTGAATG AAGAGCGTTT GGATAGCATT 780AGGAGCGGGG CGTTGATTTT ATCAGTCGTG TTAGAGCATT TGAAAACTTC CTTGATGATC 840ACTAGCGGGG TAGGGGTGAG AGAGGGCGTG TTTTTGAGCG ATTTATTGCG CCACCATTAC 900CATAAATTCC CCCCCAATAT CAACCCCTCT CTCATCTCTC TAAAAGATCG CTTTTTACCC 960CATGAAAAGC ACAGCCAAAA GGTCAAAAAA GAATGCGTGA AATTGTTTGA AGTTTTATCG 1020CCTTTGCATA AAATAGATGA AAAATACCTT TTCCATTTAA AGATTGCGGG GGAATTGGCG 1080AGCATGGGTA AGATTTTAAG TGTATATTTA GCCCACAAGC ACAGCGCGTA TTTCATTTTA 1140AACGCTTTGA GTTACGGCTT TAGCCACCAG GATAGGGCGA TCATTTGCTT ATTGGCGCAA 1200TTTAGCCATA AAAAAATCCC TAAAGACAAC GCTATCGCCC ACATGAGTGC GATGATGCCA 1260AGCCTTTTGA CCTTGCAGTG GCTGAGTTTT ATCCTTTCTT TAGCCGAAAA TTTGTGCCTG 1320ACAGACAGCC ATCATTTAAA ATACACGCTA GAAAAAAACA AGCTTGTGAT CCATTCTAAT 1380GATGCGCTTT ACTTGGCTAA AGAAATGCTC CCCAAACTCA TTAAGCCCAT TCCTTTGACG 1440ATAGAGTTTG CTTGA 1455(2) SEQ ID NO 1021 information

Sequence properties:

(A) length: 669 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...669

(xi) sequence representation: SEQ ID NO 1021, ATGGTAGGAA TGAAAACTGA GATGAAATCT TTTTTAAAAC TTTTTGCACA GCCTTTGTTG 60GTGGTTTTAG CGTTCATGTT GTTGTATGCT TTAGCGCATG CTGTGCTTGG TTTTTACGTG 120AAAAAAGACA GCGCTCCAAT GAGTCCAAAT GTAGAAAAAA GCGAGACAGA GCGCCAAAAC 180AGCACGTTTT CGCCTAAAGA AGAAGCCAAC GCAACCACAA CCGCCACAGA ACAAAACCCC 240ACCAAAGACA CAGTGCCACC TTTAGACACA GCCACACAAA AACAAGAGAT TAAACAAGAG 300ATTAAACAAG AGATTAAACA AGAGATTAAA CAAGAGATTA AACAAGAGAT TAAACAAGAG 360ATTAAACAAG AAACTAAACA AGAGCAAGAA AAAGAAAATA AGCCTAAACA AAACAGTGTC 420TCGCCCGTTC AAAACGATCA AAAAACCCCC ACAACCCCCT TAATGGGAAA AAAACCTCTA 480GAGTATAAAG TCGCAGTCAG TGGCGTGAAC GTGCGCGCTT TTCCTAGCAC AAAAGGCAAA 540ATCATTGGCT CGCTTATAAA AAATAAAAGC GTGAAGGTTT TAGAAATCCA AAACGATTGG 600GCTGAAATTG AATTTTCTCA CGAAACAAAG GGATATGTGT TTTTAAAACT TTTAAAAAAG 660GCTGAATGA 669(2) information SEQ ID NO 1022

Sequence properties:

(A) length: 408 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...408

(xi) sequence representation: SEQ ID NO 1022: GAGCCTGATG CAACAAGCCG CAGAACATTG AATCACCCCT ATTTTGGCGT TTTTGTTTTG 60TTGGTATTCA CCTTTTGGGT GTTTAACTTA ACCTTAAGGA TTCAAAGGTT TTTAAGCCGT 120AAAATGGCTC AAAAAAAGGG CGAAAAGCTC AAGCTCGCTC CCTATGAATG TGGGCCTGTG 180GCTCTCAAGC AGCCTAATAG GGTGTCCCAT CATTTTTATA TCATGGCCAT GCTTTTTATT 240TTATTTGATG TAGAAATCGT TTTCATGTTC CCTTGGGCGA TTGATTTTAA AAAGTTAGGC 300TTGTTTGGGC TCGTTGAAAT GCTAGGCTTT GTCTTCTTTT TGGCAATCGG TTTTATTTAC 360GCTTTAAAGC GAAACGCTTT GAGCTGGCAA AAATTAGAGG TGAAATAA 408(2) SEQ ID NO 1023 information

Sequence properties:

(A) length: 1908 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1908

(xi) sequence representation: SEQ ID NO 1023 CTGTCCTCCG ATCCGAGTGC TGTCAACGAC GCAAGGGATA ATCTAGGCTC AAGCACTAGG 60AATTTGCTAG ATGTCAAAGC CAATTCCCCC GCCTATCAAG CGGTGCTTTT AGCATTGAAC 120GCTGCAGTGG GCTTGTGGCA AGTTACAAGC TATGCCTTTA CCGCTTGTGG TCCTGGTAGC 180AATGAGAACG CGAATGGAGG TATCCAAACC TTTAATAATG TGCCAGGACA AAACACGACG 240ACCATCACTT GTAATTCGTA TTATGAGCCA GGACATGGCG GGCCAATATC CACTAAAAAT 300TATGCGATCA TCAACAAGGC TTATCAAATC ATTCAAAAGG CTTTGACAGC CAATGGAGAA 360GGGATCCCAG TTTTAAGCAA CACCACTACA AAACTTGATT TCACTATCAA TGGAGACAAA 420AGAACGGGTG GCGAACCAAA TAAAAAATTA GTATACCCAT GGAGTCATGG GAAAGCTATT 480TCAACCTCGT GGAATGCAAC CATAACAGCA CCAACAACAG AAAATATCAA TACAACCAAT 540AGCGCTCAAG AGCTTTTAAA ACAAGCGAGC ATCATTATCA CTACCCTGAA TAGTGCATGC 600CCAAACTTCC AAAATGGTGG TAGCGGTTAT TGGGCAGGGA TAAGTGGCAA TGGGACAATG 660TGTGGGATGT TTAAGAATGA AATCAGCGCT ATCCAAGGCA TGATCGCTAA CGCGCAAGAA 720GCTGTCGCGC AAGCCAAAAT CGTTAGTGAA AACACGCAAA ATCAAAACAG CCTAGACGCT 780GGAAAACCAT TCAACCCCTA CACAGACGCT AGTTTTGCTG AAAGCATGCT CAAAAACGCG 840CAAGCCCAAG CGGAGATTTT AAACCAAGCC GAACAAGTGG TGAAAAACTT TGAAAAAATC 900 63900 900CCTACAGCCT TTGTAAATGA CTCTTTAGGG GTGTGTTATG AAGTGCAAGG AGGTGAGCGT 960CGTGGCACCA ATCCGGGTCA GACGACTTCT AACACTTGGG GGGCAGGCTG TGCGTATGTA 1020GGACAAACGA TAACAAATCT TAAAAACAGC ATCGCCCATT TTGGCACTCA AGAGCAGCAG 1080ATACAGCAAG CCGAAAACAT CGCTGACACT CTGGTGAATT TCAAATCTAG ATACAGCGAA 1140TTGGGCAACA CTTATAACAG CATCACCACT GCGCTCTCTA ATATCCCTAA CGCGCAAAGC 1200TTGCAAAATG CGGTGAGTAA AAAGAATAAC CCCTATAGCC CGCAAGGCAT AGACACCAAT 1260TACTACCTCA ATCAAAACTC TTACAACCAA ATCCAAACCA TCAACCAAGA ACTCGGGCGT 1320AACCCCTTTA GGAAAGTGGG GATTGTTAGT TCTCAAACCA ATAATGGCGC GATGAATGGG 1380ATCGGTATTC AGGTGGGTTA CAAACAATTC TTTGGCCAAA AAAGAAAATG GGGCGCTAGG 1440TATTACGGCT TTTTTGATTA CAACCATGCG TTCATTAAAT CCAGCTTCTT CAACTCGGCT 1500TCTGACGTGT GGACTTATGG CTTTGGAGCG GACGCTCTTT ATAATTTCAT CAACGATAAA 1560GCCACCAATT TCTTAGGCAA AAACAACAAG CTTTCTGTGG GGCTTTTTGG GGGTATTGCA 1620TTAGCCGGGA CTTCATGGCT TAATTCTGAG TATGTGAATT TAGCCACCAT GAATAACGTC 1680TATAACGCTA AAATGAACGT GGCGAATTTC CAATTCTTAT TCAACATGGG AGTGAGGATG 1740AATTTAGCCA GGCCTAAGAA AAAAGACAGC GATCATGCGG CTCAGCATGG GATTGAGTTA l800GGGCTTAAAA TCCCCACCAT CAACACGAAC TACTACTCCT TTATGCGGGC TGAACTCAAA 1860TACCGAAGGC TCTATAGCGT GTATTTGAAT TACGTGTTCG CTTACTAA 1908(2) SEQ ID NO 1024 information

Sequence properties:

(A) length: 525 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...525

(xi) sequence representation: SEQ ID NO 1024: ATCAAACGCA TCATTAAATC AAACGCATCA TTAAATCAAT TAAATACCAC TAGATACAAT 60ACCCCAAGTC ATCTTTTTTT CAAAAAAGGG GTAGGAATGG CAACCATTCA ACCATTCAAC 120CATTCAACCA TTCAACCATT CAACCATTCA ACCATTCAAC CATTCAATCA TTCAATCATT 180CAATCATTCA ATCATTCAAC CATTCAAGCA ACGCTACCTT ATTTTTATAA CTATTTATCT 240TTTTACAAAA ACCTATTTAA AAATCCCCTA TTTTTTATTA TTCCCCCTTT TATTAACCCT 300TTTATTAACC CTTTTATTAA CCCTTTTATT AACCCTTTTA TTAACCCTTT TATTAACCCT 360TTTATTAACC CTTTTATTAA CCCTTTTATT AACCCTTTTA TTAACCCTTT TATTAACCCT 420TTTATTAACC CTTTTATTAA CCCTTTTATT AACCCTTTTA TTAACCCTTT TATTTCCCCT 480TCATTAACCC ACGCTACAAC ATTTTCAAAC CATTTGATTC CATAA 525(2) SEQ ID NO 1025 information

Sequence properties:

(A) length: 2247 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2247

(xi) sequence representation: SEQ ID NO 1025: ATGGAAGACT TTTTGTATAA CACCTTATAT TTCATAGAGG ATTATAAGTT GGTTGTTATT 60TTTAGTTTCA TAGGGTTAAT AGCGTTATTT TTCCTCTACA AATTCATAAA AACTCAAAAA 120AAGGTTTTTA AAGATAAAGC TAACCAGCCT CAAAAGAAAA AAAGCTTTAA AGAAATCATT 180ATAGATGGGC TGAAAGAAAG GGTTAAAACC TTTGGCTTTT GGTTGCAAGC TATACTATTA 240CTATCCTATT CTTTTATCAC ATCACGGTTA TTTTTCTTGA TTCTCTTAGG TAATTTTTAT 300GATGATAATA GATTGCCTGA GAGCGATGAT GATCTTTTTG ATATATGGGT CTATGCGATA 360CAAGATTTTC CTGCATACTA TTTTAAGGCA CTCACTTTTA GCTCGCTCAA GATTTATGGG 420TTCAATATAT CCTTAGTCGT ATATAGTTCT ATTTTATGCT CTTATATATT CATTACCTTT 480TTTGTGTGGT TCTTAAAATA CTTAACTCGG ACTAGGGACA TAGGAGCGAA TAAAAAAGTT 540GATGATCTCT TTGGTAGCGC GAGTTGGGAA ACTGAAGAGA AAATGATCAA AGCCAAGCTT 600ATCACACCCA ACAATAAAAA ACGCGCCTTT GACAAACGAG AGGTTATTGT AGGCAGGCGT 660GGCTTAGGGG ATTTTATCGC TTACGCAGGA CAGGCGTTTA TTGGCTTGAT TGCTCCTACT 720AGGAGCGGTA AGGGTGTGGG TTTCATCATG CCCAATATGA TCAATTACCC TCAAAATATC 780GTTGTGTTTG ATCCTAAGGC TGACACTATG GAAACTTGCG GGAAAATCAG AGAAAAACGC 840TTCAACCAAA AAGTGTTCAT CTATGAACCT TTCTCCTTAA AAACACACCG ATTTAATCCT 900TTCGCTTATG TGGATTTTGG TAATGATGTG GTTTTGACTG AAGACATACT CTCTCAAATT 960GACACACGCC TAAAAGGGCA TGGCATGGTG GCTAGTGGAG GGGATTTTTC CACTCAAATC 1020TTTGGATTGG CTAAGTTGGT GTTCCCTGAA AGACCTAATG AAAAAGATCC TTTTTTTAGC 1080AATCAGGCGC GAAACCTTTT TGTCATCAAT TGCAATATTT ATAGGGATCT CATGTGGACT 1140AAAAAGGGGC TTGAGTTTGT CAAAAGAAAA AAAATCATCA TGCCTGAAAC CCCCACGATG 1200TTTTTCATAG GTTCTATGGC AAGCGGTATC AACTTGATTG ATGAAGACAC AAACATGGAA 1260AAAGTCGTGT CTTTAATGGA ATTTTTTGGA GGTGAAGAAG ATAAGAGTGG CGACAATCTA 1320AGAGCGCTTA GTCCTGCCAC TAGAAACATG TGGAATAACT TCAAGACAAT GGGTGGCCCT 1380AAAGAAACTT ACAGCTCGGT TCAAGGGGTC TATACATCAG CGTTTGCGCC TTACAATAAC 1440GCCATGATCA GGAATTTCAC GAGCGCTAAT GATTTTGATT TCAGGCGTTT AAGGATCGAT 1500GCAGTGAGTA TTGGTGTGAT CGCTAATCCT AAAGAAAGCA CTATTGTTGG ACCGATATTA 1560GAGCTGTTTT TCAACGTGAT GATTTATAGC AATTTGATTC TGCCAATCCA TGATCCACAA 1620TGCAAAAGAA GCTGCTTGAT GCTCATGGAT GAATTTACGC TCTGTGGCTA TTTAGAGACC 1680TTTGTTAAAG CGGTAGGGAT CATGGCAGAA TACAACATGC GCCCCGCTTT TGTGTTTCAA 1740AGTAAGGCGC AATTAGAAAA CGACCCCCCA CTTGGTTATG GTAGGAATGG CGCTAAGACT 1800ATTTTAGACA ACCTTTCTTT GAATATGTAT TATGGGATCA ACAACGATAA CTACTATGAA 1860CATTTTGAAA AGCTTTCTAA AGTGTTAGGG AAATACACAA GGCAAGATGT GAGCCGGAGC 1920ATTGATGATA ATACGGGTAA GACCAACACT TCTATCAGCA ACAAGGAGCG GTTTTTGATG 1980ACCCCTGATG AATTGATGAC TATGGGCGAT GAGCTTATCA TTTTAGAAAA CACGCTCAAA 2040CCCATCAAGT GCCACAAGGC GCTTTACTAT GATGATCCCT TCTTCACCGA TGAGCTCATT 2100AAGGTGAGTC CAAGCTTGAG CAAGAAATAC AAATTGGGGA AAGTGCCTAA TCAAGCAACA 2160TTTTATGATG ACTTGCAAGC CGCTAAAACC AGAGGCGAAT TGAGCTATGA TAAATCTTTA 2220GTGCCTGTGG GTTCAAGCGA ACTGTGA 2247(2) SEQ ID NO 1026 information

Sequence properties:

(A) length: 1215 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1215

(xi) sequence representation: SEQ ID NO:1026: CTGAATGCAA AATCTCAATC CTCCCTAAAA AACAAAATCA CTCTTAAGAA TAAGCTAAAT 60CATGCTAGAA TTATACTTGA ATTTATTCCT AGTTTAATTT ATTTCTTAAT ACAAAAGGTG 120AGCGTTTTGA AACATTTAGC CCCACTCATT CATATCCCTT TTAAAGCCTT ATGGCTAGGC 180ACAGCCTTAA GCATGTTCTT AAGTTTGAAT TTGAACGCTG AAGAAAACCC TACTAAAACA 240GAGCCTAAGC CCGCTAAAGG GGTTAAAAAC AAGCCCAAAT CGCCTGTTAC TAATGTCATG 300ATGACCAATT GCGATAACCT TAAAGACTTT AACGCTAAGC AAAAAGAAGT TTTAAAAGCC 360GCTTATCAAT TCGGATCTAA AGAAAATTTA GGCTATGAAA TGGCGGGCAT TGCGTGGAAA 420GAATCATGCG CAGGGACTTA TAAAATCAAT TTTTCGGATC CGAGTGCGGG CATTTACCAT 480GCGTATATCC CTAGCGTTTT AAAAAGCTAT GGGCATAATA ATAGCCCCTT TTTGCGTAAC 540GTGATGGGGG AATTGCTCAT TAAAGACGAT GCGTTTGCTT CTGAAGTGGC CCTAAAAGAA 600TTGCTCTATT GGAAAACGCG CTACCATGAC AACCTAAAAG ACATGATCAA GTCTTACAAT 660AAGGGCAGTC GTTGGGAAAA AAACGAGAAA GCTAACGCTG ATGCTGAAAA ATATTATGAA 720GAGATACAAG ATAGAATCAG GCGTTTGAAA GAATCTAAAA TCTTTGACTC GCAGTCTAGT 780AATGACCAAG AATTGCAAAA AAGCGCTAAT AGCAATTTGG ATCTAGACCC TATCGGCAAC 840GCCATGCCCC AAACTTTAGC TCAAACAGAG ACCCAAAAAT CTCAAATAGA AAAATCTCAA 900ATAGAGGAAG CTCAAACGCA AAAATCTCAA GAAATGAAAG AGGCAGCTAG CGAGCAAGCC 960ATTAAGAAGC CGCTAGAAAA AGAAAAAGAT AAACCCATGT ATTTGGCTCA AATCAATAGT 1020GCTGATTTCG CGCCCGCTAA AAAAAGCCCA AAAAAACCGG CTAAAGCGAG TCCAAAACGC 1080TCCTCTAAAA ATAATATCAG CGTTAAAAGC AACACCAAAA CCGCTTCCAA AAATAAAGAA 1140GTGTGCAAAA ATTGCTCTCC AGGGCAAAGG AATGCGATTT TAGCTAACCA TATCACCCTC 1200ATGCAAGAGC TTTAA 1215(2) SEQ ID NO:1027 information.

Sequence properties:

(A) length: 813 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...813

(xi) sequence representation: SEQ ID NO 1027: ATGAAAAAGT TTGTAGTGTT TAAAACGCTC TGTTTATCGG TAGTGTTAGG TAATAGTCTT 60GTGGCAGCAG AAGGTAGCAC AGAAGTGCAA AAGCAATTGG AAAAGCCAAA AGATTATAAA 120GCAGTGAAAG GCGAGAAAAA CGCTTGGTAT CTGGGGATTA GCTATCAAGT CGGTCAGGCT 180TCACAAAGCG TTAAAAACCC CCCCAAAAGC AGTGAATTTA ACTATCCTAA GTTCCCTGTG 240GGTAAAACCG ACTATCTGGC CGTTATGCAA GGCTTAGGGC TTACTGTGGG TTATAAGCAG 300TTTTTCGGGG AGAAAAGATG GTTTGGTGCG CGCTATTACG GCTTTATGGA TTATGGGCAT 360GCCGTGTTTG GAGCGAACGC TTTGACATCA GATAATGGTG GGGTGTGCAA ACTCAATGAG 420CCATGCGCGA CCAAAGTAGG GACTATGGGC AATCTGTCTG ACATGTTCAC TTATGGTGTG 480GGTATTGACA CTTTATACAA TGTCATTAAT AAGGAAGACG CGAGTTTTGG TTTCTTTTTT 540GGGGCTCAAA TCGCGGGTAA CTCTTGGGGT AATACGACAG GGGCCTTTTT GGAAACTAAA 600AGCCCTTATA AGCACACCTC CTATAGCCTT GATCCGGCGA TTTTCCAGTT CCTTTTTAAT 660TTAGGGATTC GCACCCATAT TGGTCAGCAT CAAGAATTTG ACTTTGGCGT GAAGATTCCT 720ACTATCAATG TTTATTATTT TAACCATGGG AACTTGAGCT TCACTTACCG CCGTCAATAC 780AGCCTTTATG TAGGGTATCG TTACAATTTC TGA 813(2) SEQ ID NO 1028 information

Sequence properties:

(A) length: 759 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...759

(xi) sequence representation: SEQ ID NO 1028: ATGAAACCTT ATTTCAGTTT GGAGAAATTG GATTTATACC ATGGCGATGC GAGCGTTTTA 60: 60GAGACTTTTG AAAAAGGTTT TTATGATTTG TGCGTTACTT CACCGCCCTA TAATTTGAGT 120ATTGAATACC AAGGGAGTAA TGATTTTAGG GCTTATGACG ATTATTTGAA TTGGTGTAAA 180AATTGGCTTA AAAATTGTTA TTTTTGGGGT AAGGAACAGG CGAGGTTGTG TTTGAATGTC 240CCTTTGGATA CGAATAAGCA TGGCAAGCAA AGTTTGGGGG CTGATATTAC TATAGTGGCT 300AAAGAATGCG GTTGGAAATA CCAAAATACG ATTATTTGGA ATGAAAGCAA TATCTCAAGA 360CGCACCGCTT GGGGGAGTTG GCTGCAAGCT AGCGCACCTT ATGCGATCGC TCCTGTGGAG 420TTGATCGTTG TTTTTTATAA AAACGAATAC AAACGAAAAA AACAAACTTC TACGATGAGT 480AGAGAGGAAT TTTTACTCTA CACGAACGGG CTTTGGAATT TTAGCGGTGA ATCCAAAAAG 540CGCCTAAAGC ACCCAGCCCC ATTCCCAAGG GAATTACCCA GGCGTTGCAT CCAATTGTTT 600TCTTTTTTGG AAGACACGAT TTTTGATCCC TTTAGCGGCT CTGGCACGAC TATTTTAGAG 660GCCAACGCTT TAGGGCGTTT TAGCGTGGGT TTAGAGATTG AAAAAGAATA TTGCGAGTTG 720TCTAAAAAGC GTATTTTAGA GAGTTTGTCG TTAGTGTGA 759(2) SEQ ID NO 1029 information

Sequence properties:

(A) length: 2778 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2778

(xi) sequence representation: SEQ ID NO 1029: TTAGTTATAA TATCGCTACT AACAACACTC AAGCTAAAAT CCATTAAGGA AATCAGTATT 60AAAAAATTTA TTCTATCTTC TCTTGTTTTC GCATGTATCA ATACCGGCGT TGAAGCTTTA 120GAAAATGACG GCTCTAAACC AAACGATTTG GCTTCTCCAA AAGAAACCCC AAAAGAGGCT 180CAAAAAAATG AAGCTCAAAA CGAAACCTCT CAATCCAATC AAACGCCTAA AGAAATGAAA 240GTCAAGTCCA TTTCTTATGT CGGGCTTTCT TACATGTCTG ACATGCTCGC TAATGAAATT 300GCAAAGATTC GCGTGGGCGA TATGGTGGAT TCTAAAAAAA TAGACACCGC TGTTTTAGCT 360TTGTTCAACC AAGGGTATTT TAAAGACGTT TATGCCACTT TTGAAAACGG CATTTTAGAG 420TTTCATTTTG ATGAAAAAGC CAGGATTGCC GGGGTAGAAA TCAAGGGTTA TGGGACTGAA 480AAGGAAAAAG ACGGCTTAAA ATCCCAAATG GGGATCAAAA AGGGCGACAC CTTTGATGAG 540CAAAAATTAG AGCATGCTAA AACGGCTTTA AAAACGGCTT TAGAGGGGCA GGGCTATTAT 600GGGAGCGTGG TGGAGGTGCG CACAGAAAAG GTCAGTGAGG GAGCGTTATT GATCGTGTTT 660GATGTGAATA GGGGGGACAG TATTTATATC AAACAATCCA TTTATGAGGG AAGCGATAAA 720TTAAAACGCC GTGTGATTGA ATCTTTGAGC GCGAACAAGC AGCGCGATTT CATGGGCTGG 780ATGTGGGGCT TGAATGACGG GAAATTGCGC TTAGATCAAT TAGAATACGA TTCTTTGCGT 840ATCCAAGATG TGTATATGCG TAGGGGTTAC TTAGACGCTC ATATTTCTTC GCCTTTTTTG 900AAAACGGATT TTTCCACCCA TGACGCTAAG CTCCATTATA AGGTCAAAGA GGGGATCCAA 960TACAGGATTT CAGATATTTT AATAGAGATT GACAACCCGG TAGTCCCCTT AAAAACCTTA 1020GAAAAAgcGC TTAAAGTTAA AAGGAAAGAT GTCTTTAATA TTGAGCATTT AAGAGCGGAT 1080GCGCAAATTT TAAAAACCGA AATCGCCGAT AAGGGCTATG CGTTTGCGGT GGTGAAGCCA 1140GACTTGGATA AAGACGAAAA AAACGGGCTT GTGAAAGTCA TTTATCGTAT TGAAGTGGGC 1200GATATGGTGC ATATCAATGA TGTCATCATT TCAGGGAACC AGCGCACGAG CGATAGGATC 1260ATTAGGAGGG AATTGTTACT AGGGCCTAAA GATAAATACA ACTTGACCAA ACTGAGAAAT 1320TCCGAAAATT CTTTGAGGCG TTTAGGGTTT TTCTCTAAAG TCAAGATTGA AGAAAAAAGG 1380GTCAATAGCT CATTGATGGA TTTGTTAGTG AGCGTAGAAG AGGGGCGCAC CGGGCAGTTG 1440CAATTCGGGT TGGGCTATGG CTCTTATGGA GGGCTCATGC TTAATGGGAG CGTGAGCGAA 1500AGGAATCTTT TTGGCACAGG GCAAAGCATG AGCTTGTATG CTAACATTGC CACAGGGGGG 1560GGTAGATCTT ATCCGGGCAT GCCAAAAGGG GCGGGGCGTA TGTTTGCCGG GAATTTGAGC 1620TTGACTAATC CAAGGATTTT TGACAGCTGG TATAGCTCTA CGATCAATCT TTATGCGGAT 1680TACAGGATAA GCTACCAATA CATCCAACAA GGCGGGGGCT TTGGGGTGAA TGTCGGGCGC 1740ATGCTGGGTA ATAGAACCCA TGTGAGCTTA GGGTATAACT TGAATGTTAC CAAACTCCTT 1800GGTTTCAGCA GCCCCTTATA CAACCGCTAC TATTCCTCTG TTAATGAAGT GGCCTCTCCA 1860AGGCAATGTT CCACACCCGC ATCGGTGATT ATCAACCGCT TATCAGGCGG TAGAACTCCA 1920TTGGTTCCTG AAAGCTGTTC TAGTCCTGGA GCGATCACCA CTTCACCAGA AATAAAAGGT 1980ATTTGGGATA GGGATTACCA CACGCCTATC ACCAGTTCTT TCACCCTTGA TGTGAGCTAT 2040GACAACACCG ATGATTATTA TTTCCCTAGA AATGGGGTTA TCTTTAGTTC CTATGCGACA 2100ATGTCTGGTT TGCCAAGCTC TGGCACGCTC AATTCTTGGA ACGGGTTAGG CGGGAATGTC 2160CGTAACACCA AAGTTTATGG TAAATTCGCC GCTTACCACC ATTTGCAAAA ATATTTATTG 2220ATAGATTTGA TCGCTCGTTT TAAAACGCAA GGGGGCTATA TCTTTAGGTA TAACACCGAT 2280GATTACTTGC CCTTAAACTC CACTTTCTAC ATGGGGGGCG TAACCACGGT GAGAGGCTTT 2340AGGAACGGCT CAATCACACC TAAAGATGAG TTTGGCTTGT GGCTTGGAGG CGATGGGATT 00 2400TTTACCGCTT CTACTGAATT GAGCTATGGG GTGTTAAAAG CGGCTAAAAT GCGTTTAGCG 2460 2520AACGCTCCCA CCACGACGGC GAATTTTAAA GATTATGGCG TTGTAGGGGC TGGGTTTGAA 2580AGGGCGACTT GGAGGGCTTC TACAGGCTTA CAGATTGAAT GGATTTCGCC CATGGGGCCT 2640TTGGTGTTGA TTTTCCCTAT AGCGTTTTTC AACCAATGGG GCGATGGCAA TGGCAAAAAA 2700TGTAAAGGGC TGTGCTTTAA CCCTAACATG AACGATTACA CGCAACATTT TGAATTTTCT 2760ATGGGAACAA GGTTTTAA 2778(2) SEQ ID NO 1030 information

Sequence properties:

(A) length: 576 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...576

(xi) sequence representation: SEQ ID NO1030: ATGAAACAAC TATTTTTGAT TATTGGAGCC CCAGGGAGTG GTAAAACCAC TGACGCAGAG 60CTTATCGCTA AGAATAACAG CGAAACAATC GCTCATTTTT CTACTGGGGA TTTACTCAGG 120GCTGAGAGCG CTAAAAAGAC TGAGCGAGGC TTATTGATTG AGAAATTCAC TTCTCAAGGC 180GAATTAGTGC CTTTAGAAAT TGTGGTAGAA ACGATCCTTT CAGCGATTAA AAGCTCTAGT 240AAAGGGATCA TTTTAATTGA TGGCTATCCC AGGAGCGTGG AGCAAATGCA AGCTTTGGAT 300AAGGAATTGA ACGCTCAAAA TGAAGTGATC TTAAAAAGCG TGATTGAAGT AGAAGTGAGC 360GAAAACACCG CTAAAGAAAG GGTTTTAGGG CGCTCTAGGG GGGCTGATGA TAATGAAAGG 420GTGTTTCATA ACCGCATGCG GGTGTTTTTA GATCCGTTGG TTGAAATCCA AAACTTCTAC 480AAGGCCAAGC ATTTGCATAA AATTATCAAT GGTGAAAGAA GCATTGAAGA AATCGTGAAT 540GAAATGCAAA AATATATTTT GTCTTTTGCA AATTAA 576(2) SEQ ID NO 1031 information

Sequence properties:

(A) length: 1023 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1023

(xi) sequence representation: SEQ ID NO 1031: TTGAGTTCGT TATGGCTGAC AAACCCCTTA AATGCCCATG AAAAGAATGG CGCGTTTGTG 60GGGATTAGCT TGGAAGTGGG TAGGGTCGAT CAAAAGACCA ACGCTTATAG AAACGGCGAG 120TTGTTTCAAG TGCCTTTTCG CGATGTTTCG GCTAATGATG ATGGCAAAGT CCCTGATGGG 180CAGACCGGTG GCTGTCAGCC AGCTTCAGGG ACTCCAGGAA CGCCAGGCTA TACTAAAGCT 240AATTGCGTGG TCAATTGGAC TTCTCGCACC ATGCTTAGCA CCAATAAGGA CATTCCTGGC 300CGTAACCAGC CGATGTATGG GCTAGGCGTG ATGACAGGGT ATAAGCATTT TGTGGGTAAA 360AAAAGGTGGT TTGGGCTGCG TTATTATGGC TTTTTTGATT ACGGGCATAC CAATTTCTCT 420AACTCTAGGG CCGCTAACGC CATATCGCCC TTTTATTTGA GCGATCAAAA AGCGGACATG 480TATACTTATG GTTTTGGCAC AGACATGCTT TTTAACGTTA TAGACAAGCC TAAAGCCACG 540GCCGGGTTTT TTGTGGGCGT GAATTTTGCG GGTAACACTT GGACTAATAA TCGTGTGGGG 600TATTTTAAGG ACGGGTATGT TTATGGCGTC AATACGGACG CTGACGCTTA CATGACTAAC 660GCTGATGGCA CGATCACATG CGGAGACACG ACGCCGGCGA GTTGTAATGT GGGGATTAAC 720CCTAACAGCG TCTATACCAC AGGAAAATTA AACGCTAAAG TGAATCACAC GATTTTCCAA 780TTTTTAGTGA ATGTGGGCAT TAGAACCAAT ATTTTTGAAC ACCATGGCAT TGAGTTTGGT 840ATCAAAATCC CCACGCTCCC TAATTACTTT TTCAAAGGTT CTACTACTAT AAGAGCGAAA 900AAACAAGGCC CACTAGAGAA TGGGAACCCG ACTACTATCA CCGGAGCAGA AACCAATTTC 960AGCTTAACCC AAACCTTACG CCGTCAGTAT TCTATGTATT TGCGTTATGT TTATACTTTT 1020TAA 1023(2) SEQ ID NO 1032 information

Sequence properties:

(A) length: 1587 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1587

(xi) sequence representation: SEQ ID NO:1032: ATGAAATTAA AAAAACGAAA AGTTGCGGCT ACATTGCTAA AGCGTTTGAC CTTGCCACTA 60TTGTTCACTA CGGGTTCATT AGGGGCGGTT ACTTATGAAG TGCATGGGGA TTTTATCAAC 120TTCTCCAAAG TGGGTTTTAA CCGTTCGCCT ATTAACCCTG TTAAAGGTAT CTATCCTACA 180GAAACTTTTG TTAACCTTAC GGGTAAGCTA GAGGGGTCTG TGCATTTAGG TAGGGGATGG 240ACCGTGAATG TAGGCGGTGT TTTGGGCGGA CAAGTTTATG ATAACACTAG GTATGATAGG 300TGGGCAAAGG ATTTTACCCC CCCAAGCTAT TGGGATAAAA CTTCTTGCGG CACTGATTCT 360TTGAGCCTTT GTATGAATGC GACTAAAATG TGGCAACAGC AAGGGCCAGG TGGTATCATT 420GACCCTAGGG GTATTGGCTA TATGTATATG GGTGAGTGGA ACGGCTTGTT CCCTAATTAC 480TATCCGGCTA ACGCCTACTT GCCCGGGCAT TCAAGGCGCT ATGAAGTTTA TAAAGCGAAT 540CTTACCTATG ACAGCGACAG AGTCCATATG GTAATGGGGC GCTTTGATGT TACCGAGCAG 600 TATCCGGCTA ACGCCTACTT GCCCGGGCAT TCAAGGCGCT ATGAAGTTTA TAAAGCGAAT 540 600GAGCAAATGG ATTGGATTTA CCAATTGTTC CAAGGTTTTT ATGGGACTTT CAAGCTTACT 660AAGAACATGA AATTCTTGCT CTTTAGCTCT TGGGGTCGTG GTATCGCTGA TGGTCAATGG 720TTGTTCCCTA TCTATCGTGA AAAGCCTTGG GGTATTCATA AGGCGGGTAT TATTTATCGC 780CCTACAAAGA ATCTAATGAT CCACCCTTAT GTGTATCTCA TCCCAATGGT AGGTACATTG 840CCCGGTGCTA AAATAGAATA CGATACCAAT CCTGAGTTTA GCGGTAGAGG TATAAGGAAT 900AAAACGACTT TCTATGTGTT GTATGACTAT CGTTGGAATA ACGCTGAATA CGGCCGTTAC 960GCACCCGCTC GTTATAACAC TTGGGATCCG TTCTTGGATA ATGGTAAGTG GCGTGGCTTG 1020CAAGGTCCTG GTGGTGCGAC GCTCTATTTG CACCACCACA TAGACATTAA CAACTACTTT 1080GTGGTTGGTG GTGCTTACCT CAACATCGGT AACCCTAACA TGAACTTAGG TACTTGGGGT 1140AACCCTGTGG CTCTTGATGG TATCGAACAA TGGGTCGGTG GCATCTACAG CTTAGGCTTT 1200GCGGGGATTG ACAACATTAC CGATGCTGAT GCGTTCACTG AGTATGTTAA AGGTGGAGGT 1260AAGCATGGTA AGTTCAGTTG GAGCGTTTAT CAGCGCTTCA CTACCGCACC AAGGGCTTTG 1320GAATATGGTA TTGGTATGTA TCTAGACTAT CAGTTCAGCA AGCATGTTAA AGCGGGTCTC 1380AAACTCGTGT GGTTAGAGTT CCAAATCCGT GCGGGTTACA ACCCTGGAAC CGGTTTCCTT 1440GGGCCAAACG GTCAGCCCCT CAACTTGAAT AATGGTTTGT TTGAATCTTC GGCGTTCGCG 1500CAAGGCCCTC AAAACATGGG TGGTATCGCA AAAAGCATTA CTCAAGACAG AAGCCATTTG 1560ATGACACACA TCAGTTATAG TTTCTAA 1587(2) SEQ ID NO 1033 information

Sequence properties:

(A) length: 705 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...705

(xi) sequence representation: SEQ ID NO 1033: ATGACAAAAA TTGCCATGGC TAATTTCAAA TCCGCTATGC CTGTTTTTAA AAGCCATGCG 60TATTTAAAAG AATTGGAAAA AACTTTAAAG CCGCAGCATT TTGATAGGGT GTTTGTATTC 120CCTGATTTTT TGGGGTTATT GCCTAACGCG TTTTTGCATT TCACTTTAGG AGCGCAAAAC 180GCTTACCCTA GAGATTGTGG GGCTTTTACC GGTGAAATCA CTTCCAAACA TTTAGAAGAA 240CTGAAAATCC ACACGCTTTT AATAGGGCAT AGCGAGAGGC GAGTGCTTTT AAAGGAAAGC 300CCTAGCTTTT TGAAAGAAAA ATTTGATTTT TTTAAAGGTA AAAATTTTAA AATTGTCTAT 360TGTATTGGCG AAGATTTAAC GACCAGAGAA AAGGGTTTTA GGGCTGTAAA GGAATTTTTA 420AGCGAGCAAT TAGAAAATAT TGATCTTAAT TATTCCAATT TAATTGTGGC TTATGAGCCT 480ATTTGGGCGA TTGGCACTAA AAAAAGCGCG TCTTTAGAAG ATATTTACCT CACGCATGGT 540TTTTTAAAGC AAATCTTAAA TCAAAAAACG CCCTTATTGT ATGGGGGGAG CGTGAATGCG 600CAAAACGCTA AAGAAATTTT AGGGATTGAT AGCGTGGATG GCTTATTGAT TGGGAGCGCG 660TCTTTGGAAT TAGAAAATTT TAAAACAATC ATTTCATTTT TATAA 705(2) SEQ ID NO 1034 information

Sequence properties:

(A) length: 1398 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1398

(xi) sequence representation: SEQ ID NO:1034: ATGTTCATTT ATGATACCAA ATTAAAACAA AAAGTCCCTT TTGAGCCTTT AGTCCACAAT 60AAGGCGAATA TTTATGTGTG TGGGCCTACG GTGTATGATG ACGCTCATTT AGGGCATGCC 120AGGAGCGCGA TTGCTTTTGA TTTGTTGAGG CGCACGCTTG AATTGAGCGG CTATGAAGTG 180GTGCTAGTAA GGAATTTCAC GGATATTGAC GATAAGATTA TCAATAAAGC CTTCAAAGAA 240AACAAAAGCA TTCAAGAATT AAGCAGCATT TACATTGAAT CTTACACGAG GGATCTAAAC 300GCTTTGAACG TGAAACAACC CAGCCTAGAG CCTAAAGCGA GCGAGTATTT AGACGCTATG 360GTGCGCATGA TTGAAACGCT TTTAGAAAAA AATTTCGCTT ATAGAGTTTC TAATGGGGAT 420ATTTATTTAG ACACGAGCAA GGACAAAGAT TACGGCTCTT TGAGCATGCA TAATAGCAGC 480GTGGAATTTA GCCGTATCGG TTTGGTGCAA GAAAAACGGC TTGAGCAGGA TTTTGTGTTA 540TGGAAAAGCT ATAAGGGGGA TAATGATGTG GGCTTTGATA GCCCTTTAGG CAAAGGGCGC 600CCTGGCTGGC ACATAGAATG CTCTAGCATG GTTTTTGAAA CTTTAGCGCT CGCTAACGCC 660CCTTATCAAA TTGATATTCA TGCTGGCGGA ACGGATTTGT TATTCCCCCA CCATGAAAAT 720GAAGCGTGCC AAACCCGTTG TGCCTTTGGC GTGGAGATCG CTAAATACTG GATGCACAAT 780GGCTTTGTGA ATATCAATAA CGAAAAAATG TCTAAAAGTT TAGGGAATAG CTTTTTCATT 840AAAGACGCCC TCAAAAACTA TGATGGCGAG ATTTTGCGTA ATTACTTACT AGGGGTGCAT 900TACCGCTCTG TTTTGAATTT CAATGAAGAA GACTTGTTAA TGAGTAAAAA ACGCTTGGAT 960AAAATCTATC GTTTGAAACA GCGCGTTTTA GGGACTTTAG GAGGAATAAA TCCAAACTTT 1020AAAAAAGAAA TTTTAGAATG CATGCAAGAT GATTTAAACG TTTCTAAAGC GTTGAGCGTT 1080TTAGAAAGCA TGCTTTCTTC TACGAATGAA AAACTGGATC AAAACCCTAA AAACAAGGCT 1140TTGAAAGGCG AAATTTTAGC GAATCTGAAA TTCATAGAAG AACTGCTTGG TATTGGGTTT 1200AAAGACCCTA GCGCGTATTT CCAATTAGGC GTGAGCGAGA GCGAAAAACA AGAAATTGAA 1260AACAAGATAG AAGAAAGAAA ACGTGCCAAA GAACAAAAAG ATTTTTTAAA AGCCGATAGC 1320ATCAGAGAAG AGCTTTTACA ACAAAAAATC GCTTTGATGG ACACCCCACA AGGCACGATT 1380TGGGAGAAGC TTTTTTAA 1398(2) SEQ ID NO 1035 information

Sequence properties:

(A) length: 3642 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...3642

(xi) sequence representation: 1035: ATGAAACAAT TTAAAAAGAA ACCAAAAAAG ATAAAACGAT CGCATCAAAA TCAAAAAACA 60ATCTTAAAGC GTCCTTTATG GCTTATGCCT TTACTGATTG GCGGGTTTGC TAGTGGGGTG 120TATGCGGATG GAACAGACAT TTTGGGGCTT AGTTGGGGGG AAAAAAGCCA AAAGGTATGC 180GTGCATCGTC CATGGTATGC TATATGGAGT TGCGATAAAT GGGAGGAAAA AACACAACAA 240TTTACAGGAA ACCAACTCAT CACAAAAACT TGGGCAGGGG GTAATGCGGC TAACTACTAC 300CACTCTCAAA ACAACCAAGA CATCACAGCC AATTTAAAAA ATGATAACGG CACTTATTTT 360TTAAGCGGTC TGTATAACTA CACCGGAGGG GAATATAATG GGGGGAATTT AGACATTGAA 420TTAGGCAGTA ACGCTACTTT TAATCTAGGT GCGAGTAGTG GGAATAGCTT CACTTCTTGG 480TATCCTAATG GGCATACTGA TGTTACTTTT AGCGCTGGGA CTATCAATGT GAATAACAGC 540GTAGAAGTGG GCAATCGTGT GGGATCGGGA GCTGGCACGC ACACCGGCAC AGCCACTTTA 600AACTTGAACG CTAATAAGGT TACTATCAAT TCCAATATCA GCGCGTATAA AACTTCGCAA 660GTGAATGTAG GCAATGCTAA CAGCGTTATT ACCATTAATT CGGTTTCTTT AAATGGGGAT 720ACTTGCAGTT CTTTAGCTAG GGTGGGCGTA GGGGCTAATT GCTCCACTTC TGGGCCTAGC 780TATTCTTTTA AAGGGACGAC TAACGCTACT AACACGACTT TTAGCAATTC AAGCGGCAGT 840TTCACTTTTG AAGAGAACGC CACTTTTAGC GGGGCGAAAT TAAATGGGGG GGCATTCACT 900TTCAATAAAA AGTTTAACGC TACCAATAAT ACCGCTTTTA ATAGCGGTAG TTTTACTTTT 960AAAGGCACAA GCTCTTTTAA TGGTGCGAAT TTTAGTAACG CTTCCTATAC TTTTAATAAT 1020CAAGCCACTT TCCAAAACAG CTCCTTTAAT GGGGGGACTT TTACTTTTAA TGACCAGACC 1080AATCAAAGCA CCCAGCACCC CCAAATTCAA AACAGCTCTT TTAGCGGCAG TGCTACCACT 1140CTTAAGGGTT TTGCGACTTT TGAGCAAGCC TTTAACAATT CAAACCACCA ACTAACGATA 1200CAAAACGCTT CCTTTAATAA CGCTACTTTC AACAATACCG GTAAAATCAC TATAGAAAAA 1260GATGCGAGCT TTAATAACAC TTCGTTCAAC ACTCCTGTTG ATACAAACAA CATGACTATT 1320AGTGGTGGCG TTACTTTAAG CGGTAAAAAT GACTTGAAAA ATGGTGCAAC CCTTGATTTT 1380GGGAGTTCTA AAATCACTCT CACTCAAGGG ACGACTTTCA ACCTCACAAG TTTAGGCAGT 1440GAGAAGAGCG TAACGATTTT AAATTCTAGA GGTGGGATCA CTTACAATCA TCTTTTAAAC 1500CATGCGATCA ATAGCTTGAC AAACGCCCTA AAAACGAACG AAAGCTCTTC AAAACCGCAA 1560AGTTTCGCTC AAGGTTTGTG GGATATGATC ACTTACAATG GGGTTACCGG GCAGCTTTTG 1620AATGAAAACG CTGCAACATC TAAACCCACT GACTCTTCGC CCTCTAAATC CTCTACAAAC 1680TCTACGCAAG TCTATCAAGT GGGTTACAAA ATAGGGGATA CTATCTACAA ACTGCAAGAA 1740ACTTTCAGCC ACAATTCCAT TATTATTCAG GCTTTAGAGA GCGGGACTTA CACGCCACCC 1800CCTCTCATTA ACGGCTCCAA ATTTGACTTA TCCGCTTCAA ATTATATCAA TGCTGACATG 1860CCTTGGTATA ACCATAAATA TTATATTCCT AAATCCCAAA ATTTTACAGA GAGCGGGACT 1920TATTACTTGC CGAGCGTTCA AATATGGGGG AGCTACACTA ACTCGTTTAA ACAAACCTTT 1980AGCGCAAGTA ATAGCAATCT GGTGATTGGG TATAACGCAA CATGGACTGA TCACAATGTT 2040TCTTCTAGCG ACACGGTGGC TTTTGGGGAC ACTTCAGGGA GCGCTCTTAA TGGGCATTGC 2100GGGCCTTGGC CCTATTACCA ATGCACAGGC ACGACTAACG GCACTTATAG CGCTTATCAT 2160GTCTATATCA CAGCGAATCT GCGTTCTGGC AATCGTATAG GCACCGGTGG GGCAGCCAAT 2220CTAATCTTTA ATGGGGTAGA TAGTATCAAT ATCGCTAACG CTACCATCAC GCAACATAAC 2280GCCGGGGCTT ATTCAAGCTC TATGACTTTT TCCACGCAAA ACATGGACAA TTCGCAGAAT 2340TTGAATGGCC TAAATTCTAA CGGCAAGCTT TTGGTGTATG GCACAACTTT CACTAACCAA 00 2400GCCAAAGACG GGAAATTCAT TTTCAATGCA GGGCAAGCGA CTTTTGAAAA CACCAACTTT 2460 2520AATAGCGGTT CGTTTGAGAT TGGCGCAAAA AATACTATTT TTAATAACGC TAATTTTAAC 2580AACAGCACTT CTTTTAATTT CAATAATTCT AGCGCGACCA CTTCGTTTGT GGGGGATTTC 2640ACTAACGCTA ATTCAAATTT GCAAATCGCT GGGAACGCTG TTTTTGGGAA CTCTACTAAT 2700GGCTCTCAAA ATACCGCTAA TTTTAATAAT ACCGGCTCTG TTAATATTGC AGGGAATGCA 2760ACCTTTGATA ACGTGGTATT TAACAGCCCT ACGAACACGA GCGTGAAAGGGAAAGTTACT 2820CTCAATAACA TCACTTTAAA AAACTTGAAC GCTCCTTTGT CTTTTGGCGA TGGGACGATT 2880GTTTTTAGCG CTCATTCGGT GATTAATATT GGTCAAGCTA TCACAAATGG CAACCCTATC 2940ACCCTTGTAA GCTCTTCTAA AGCAATTGAA TACAACGACG CTTTCAGTAA AAATCTATGG 3000CAGCTCATCA ACTACCAAGG GCATGGGGCT AGCAGTGAAA AGCTCGTTTC TAGTGCGGGT 3060AATGGCGTCT ATGATGTGGT GTATTCTTTC AACAACCAAA CCTACAATTT CCAAGAGGTT 3120TTTTCACCCA ACAGCATTTC TATCCGGCGT TTGGGCGTTG GCATGGTGTT TGATTATGTG 3180GATATGGAAA AATCGGATCG TTTGTATTAT CAAAACGCTC TCGGTTTTAT GACCTACATG 3240CCTAATAGCT ATAACAATAA TTTAGGGAAT TTAAACAACA CCATTTACTA TTACGACAAC 3300AGCATTGACT TTTATGCGAG CGGGAAAACT CTATTCACTA AAGCGGAATT TTCTCAAACG 3360TTCACTGGGC AAAACAGCGC GATCGTTTTT GGGGCTAAAA ATATATGGAC GAGCGTAAGC 3420GATGCGCCGC AATCTAATGT GATCATTCGC TTTGGGGACA ATAAGGGAGC AGGGAGTAAT 3480GATGCGAGTG GGCATTGCTG GAATTTGCAA TGCATAGGCT TTATCACAGG GCATTATGAA 3540GCGCAAAAGA TTTACATCAC CGGCAGTATT GAAAGCGGGA ACCGCATTTC TAGCGGTGGG 3600GCGCGAGCCT TAATTTTAAC GGGCTTCAAG GCATTCTTTT AA (2) SEQ ID NO 1036 information

Sequence properties:

(A) length: 1503 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1503

(xi) sequence representation: SEQ ID NO 1036 ATGGCTGAAT GGAAAACGGA CACAGAAGAA GTCAAAAAGG TTGTTGGAAG ATGCAGGGAA 60TTTAAAAGATCCCTGCAAGA AGAAAAATGC AGTCCATTTA TCAAAGACCT TGATAGTTAC 120GCGCTAAAAA TCATAGTGGA GCGCAGAAAA ACTGAAATGC AATTGGAAAA AGCCATAGGA 180GAATTAAAAA AAGCCAAAAG CAATGAAGAT GACGCTAAAG TTGCTTTAAG AGTCTTGCAA 240GGTGCTTCTG TCGTCTCGTG GATTTGGCCT CCTGCTAGAA TAGCTGCTAC GGCAGCCATT 300GTAGCCGCTG AAGCTGTTTT GAAATTTATG AAAGAAGACA CAGAAAAATG CAAAAGGAAT 360GTGGAGCTAT TAGAACGAAT GCTTGAAATC TACTCGAATC AAGCCAAAGC GAGCGCGAAT 420CTTATGAATC AAGCTTGGGA GGGCATTAAA AAGAGGTTGC ATTTTTATAC TGATAAGCAC 480CAGGAATTTA TCAGGCGTTT GAAACAAGCG AGCGATGCGA TAGATAACGA ATACAACTTT 540CCAACTCCAG GCGTTTTATT GGAATACGAT TTTGAACGGC CTGCTATCTC TTATACCCCT 600AAAAAAAGCG TTTTTAATGA GCGCTTGAAG GATTTGAGGG AAAATTTTAG CGCTTCTTTA 660TACGCTGATT TGAAAGACAA GATCCATCAT AACGCCTTGT CTAACGATGA TTTAGAACGC 720ATGATAGCTT TTAGAGAGCA AGAATTTGAA AAGAGTTTAG AGGATTGGAT GGGTGCATAT 780TCTTATGATG AAAACCCTAA CGATGAATTA GATCGCATGG CAATATCTAA AGAGCAGGAG 840TTGGAAAAGA GTTTAGAGGA TTTGATGCCA AGCGTTTTAG GCGTGCCTTC TTATAACGAA 900AGCTTGACTT TAGCCAAAAA TCGTTGCGTT AAAAACTTTA AGGAAGCTTT AGAAGGTTTT 960ACAGAAAAAA TCAAAGAATC CCCTAACGAT TCAAACGCTA TCAATGAAGC CTTTGATAAT 1020TTAGAAACAG AGTTAGAGCG CGCTACAGAA AATTTGAGTC AAAAAATCGA TCCCGTTTTA 1080GAACGGAATG AAAATTATAC GCAAAAAGCG TTGGAGTATA GGGAGTTTTT AGAAAGCCGT 1140AAAGAGAGCT TTATTGTAGA TGAAAAAAAC CCCTATCCGG AAGAAGTCAG CTTTAATGAA 1200TGGCGTTGGG CGGAATTTGA TAGCGTTTTT AGCGCCATTG TGCCTTTAGA AGATTTAAAT 1260AAAACCGCAT GCGCTCATCA TGCCCTAAAG GCTTTACAAG CTACGCTTAA AGACAACGAT 1320TTGGGCTTTG ATGCGACAGA GTTGGAACAG ATCGCAAAAG GATTCATCCC TAGGGGGTAT 1380TTGTGGCATT TTGACGCGAA TGTTTTAGGG AATTTAGCGC TGGTGAGAGA AGAGTTATTA 1440TTAGGCGTGA AACACACGAA AGGATATTCA CTATGGACAG AATTTCTACA GAAACAGAAT 1500TGA 1503(2) SEQ ID NO 1037 information

Sequence properties:

(A) length: 245 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(iv) original source:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...245

(xi) sequence representation: SEQ ID NO 1037: Met Gln Phe Gln Lys Thr Leu Ser Ser Leu Ser Leu Phe Leu Ser Leu 151015 Ser Leu Phe Leu Ser Phe Ser Ile Ala Glu Glu Asn Gly Ala Tyr Ala

20 25 30Ser Val Gly Phe Glu Tyr Ser Ile Ser His Ala Val Glu His Asn Asn

35 40 45Pro Phe Leu Asn Gln Glu Arg Ile Gln Thr Ile Ser Asn Ala Gln Asn

50 55 60Gln Ile Tyr Lys Leu Asn Gln Ile Glu Asn Glu Ile Thr Asn Met Gln65 70 75 80Asn Thr Phe Asn Tyr Thr Asn Asn Ala Leu Lys Asn Asn Ala Lys Leu

85 90 95Thr Pro Thr Glu Met Gln Ala Glu Gln Tyr Tyr Leu Gln Ser Thr Leu

100 105 110Gln Asn Ile Glu Lys Ile Val Met Leu Ser Gly Gly Val Ala Ser Asn

115 120 125Pro Lys Leu Val Gln Ala Leu Glu Lys Met Gln Glu Pro Ile Thr Asn

130 135 140Pro Leu Glu Leu Val Glu Asn Leu Lys Asn Leu Glu Leu Gln Phe Ser145 150 155 160Gln Ser Gln Asn Ser Met Leu Ser Ser Leu Ser Ser Gln Ile Ala Gln

165 170 175Ile Ser Asn Ser Leu Asn Ala Leu Asp Pro Ser Ser Tyr Ser Lys Asn

180 185 190Val Ser Ser Met Tyr Gly Val Gly Leu Ser Val Gly Tyr Lys His Phe

195 200 205Phe Thr Lys Lys Lys Asn Gln Gly Phe Arg Tyr Tyr Leu Phe Tyr Asp

210 215 220Tyr Gly Tyr Thr Asn Phe Gly Phe Val Gly Asn Gly Phe Asp Gly Leu225 230 235 240Gly Lys Met Asn Asn

245(2) SEQ ID NO 1038 message

Sequence properties:

(A) length: 632 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...632

(xi) sequence representation: 1038 SEQ ID NO: Met Lys Pro Thr Asn Glu Pro Lys Lys Pro Phe Phe Gln Ser Pro Ile 151015 Val Leu Ala Val Leu Gly Gly Ile Leu Leu Ile Phe Phe Leu Arg Ser

20 25 30Phe Asn Ser Asp Gly Ser Phe Ser Asp Asn Phe Leu Ala Ser Ser Thr

35 40 45Lys Asn Val Ser Tyr His Glu Ile Lys Gln Leu Ile Ser Asn Asn Glu

50 55 60Val Glu Asn Val Ser Ile Gly Gln Thr Leu Ile Lys Ala Ser His Lys65 70 7580Glu Gly Asn Asn Arg Val Ile Tyr Ile Ala Lys Arg Val Pro Asp Leu

85 90 95Thr Leu Val Pro Leu Leu Asp Glu Lys Lys Ile Asn Tyr Ser Gly Phe

100 105 110Ser Glu Ser Asn Phe Phe Thr Asp Met Leu Gly Trp Leu Met Pro Ile

115 120 125Leu Val Ile Leu Gly Leu Trp Met Phe Met Ala Asn Arg Met Gln Lys

130 135 140Asn Met Gly Gly Gly Ile Phe Gly Met Gly Ser Ala Lys Lys Leu Ile145 150 155 160Asn Ala Glu Lys Pro Asn Val Arg Phe Asn Asp Met Ala Gly Asn Glu

165 170 175Glu Ala Lys Glu Glu Val Val Glu Ile Val Asp Phe Leu Lys Tyr Pro

180 185 190Glu Arg Tyr Ala Asn Leu Gly Ala Lys Ile Pro Lys Gly Val Leu Leu

195 200 205Val Gly Pro Pro Gly Thr Gly Lys Thr Leu Leu Ala Lys Ala Val Ala

210 215 220Gly Glu Ala His Val Pro Phe Phe Ser Met Gly Gly Ser Ser Phe Ile225 230 235 240Glu Met Phe Val Gly Leu Gly Ala Ser Arg Val Arg Asp Leu Phe Glu

245 250 255Thr Ala Lys Lys Gln Ala Pro Ser Ile Ile Phe Ile Asp Glu Ile Asp

260 265 270Ala Ile Gly Lys Ser Arg Ala Ala Gly Gly Met Ile Ser Gly Asn Asp

275 280 285Glu Arg Glu Gln Thr Leu Asn Gln Leu Leu Ala Glu Met Asp Gly Phe

290 295300Gly Ser Glu Asn Ala Pro Val Ile Val Leu Ala Ala Thr Asn Arg Pro305 310 315 320Glu Ile Leu Asp Pro Ala Leu Met Arg Pro Gly Arg Phe Asp Arg Gln

325 330 335Val Leu Val Asp Lys Pro Asp Phe Asn Gly Arg Val Glu Ile Leu Lys

340 345 350Val His Ile Lys Gly Val Lys Leu Ala Asn Asp Val Asn Leu Gln Glu

355 360 365Val Ala Lys Leu Thr Ala Gly Leu Ala Gly Ala Asp Leu Ala Asn Ile

370 375 380Ile Asn Glu Ala Ala Leu Leu Ala Gly Arg Asn Asn Gln Lys Glu Val385 390 395 400Lys Gln Gln His Leu Lys Glu Ala Val Glu Arg Gly Ile Ala Gly Leu

405 410 415Glu Lys Lys Ser Arg Arg Ile Ser Pro Lys Glu Lys Lys Ile Val Ala

420 425 430Tyr His Glu Ser Gly His Ala Val Ile Ser Glu Met Thr Lys Gly Ser

435 440 445Thr Arg Val Asn Lys Val Ser Ile Ile Pro Arg Gly Met Ala Ala Leu

450 455 460Gly Tyr Thr Leu Asn Thr Pro Glu Glu Asn Lys Tyr Leu Met Gln Lys465 470 475 480His Glu Leu Ile Ala Glu Ile Asp Val Leu Leu Gly Gly Arg Ala Ala

485 490 495Glu Glu Val Phe Leu Glu Glu Ile Ser Thr Gly Ala Ser Asn Asp Leu

500 505 510Glu Arg Ala Thr Asp Ile Ile Lys Gly Met Val Ser Tyr Tyr Gly Met

515 520 525Ser Ser Val Ser Gly Leu Met Val Leu Glu Lys Gln Arg Asn Ala Phe

530 535 540Leu Gly Gly Gly Tyr Gly Ser Ser Arg Glu Phe Ser Glu Lys Thr Ala545 550 555 560Glu Glu Met Asp Leu Phe Ile Lys Asn Leu Leu Glu Glu Arg Tyr Gln

565 570 575His Val Lys Gln Thr Leu Ser Asp Tyr Arg Glu Ala Ile Glu Ile Met

580 585 590Val Lys Glu Leu Phe Asp Lys Glu Val Ile Thr Gly Glu Arg Val Arg

595 600 505Glu Ile I1e Ser Glu Tyr Glu Ala Ala Asn Asn Leu Glu Ser Arg Leu

610615620 Ile Pro Leu Glu Glu Gln Ala Ser 625630 (2) SEQ ID NO:1039 message

Sequence properties:

(A) length: 1288 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1288

(xi) sequence representation: SEQ ID NO 1039: Met Glu Ile Gln Gln Thr His Arg Lys Ile Asn Arg Pro Leu Val Ser 151015 Leu Val Leu Ala Gly Ala Leu Ile Ser Ala Ile Pro Gln Glu Ser His

20 25 30Ala Ala Phe Phe Thr Thr Val Ile Ile Pro Ala Ile Val Gly Gly Ile

35 40 45Ala Thr Gly Thr Ala Val Gly Thr Val Ser Gly Leu Leu Ser Trp Gly

50 55 60Leu Lys Gln Ala Glu Glu Ala Asn Lys Thr Pro Asp Lys Pro Asp Lys65 70 75 80Val Trp Arg lle Gln Ala Gly Lys Gly Phe Asn Glu Phe Pro Asn Lys

85 90 95Glu Tyr Asp Leu Tyr Lys Ser Leu Leu Ser Ser Lys Ile Asp Gly Gly

100 105 110Trp Asp Trp GLy Asn Ala Ala Arg His Tyr Trp Val Lys Gly Gly Gln

115 120 125Trp Asn Lys Leu Glu Val Asp Met Lys Asp Ala Val Gly Thr Tyr Lys 130 135 140Leu Ser Gly Leu Arg Asn Phe Thr Gly Gly Asp Leu Asp Val Asn Met145 150 155 160Gln Lys Ala Thr Leu Arg Leu Gly Gln Phe Asn Gly Asn Ser Phe Thr

165 170 175Ser Tyr Lys Asp Ser Ala Asp Arg Thr Thr Arg Val Asn Phe Asn Ala

180 185 190Lys Asn Ile Ser Ile Asp Asn Phe Val Glu Ile Asn Asn Arg Val Gly

195 200 205Ser Gly Ala Gly Arg Lys Ala Ser Ser Thr Val Leu Thr Leu Gln Ala

210 215 220Ser Glu Gly Ile Thr Ser Ser Lys Asn Ala Glu Ile Ser Leu Tyr Asp225 230 235 240Gly Ala Thr Leu Asn Leu Ala Ser Asn Ser Val Lys Leu Asn Gly Asn

245 250 255Val Trp Met Gly Arg Leu Gln Tyr Val Gly Ala Tyr Leu Ala Pro Ser

260 265270Tyr Ser Thr Ile Asn Thr Ser Lys Val Gln Gly Glu Val Asp Phe Asn

275 280 285His Leu Thr Val Gly Asp Gln Asn Ala Ala Gln Ala Gly Ile Ile Ala

290 295 300Ser Asn Lys Thr His Ile Gly Thr Leu Asp Leu Trp Gln Ser Ala Gly305 310 315 320Leu Asn Ile Ile Ala Pro Pro Glu Gly Gly Tyr Lys Asp Lys Pro Asn

325 330 335Ser Thr Thr Ser Gln Ser Gly Thr Lys Asn Asp Lys Lys Glu Ile Ser

340 345 350Gln Asn Asn Asn Ser Asn Thr Glu Val Ile Asn Pro Pro Asn Asn Thr

355 360 365Gln Lys Thr Glu Thr Glu Pro Thr Gln Val Ile Asp Gly Pro Phe Ala

370 375 380Gly Gly Lys Asp Thr Val Val Asn Ile Phe His Leu Asn Thr Lys Ala385 390 395 400Asp Gly Thr Ile Lys Val Gly Gly Phe Lys Ala Ser Leu Thr Thr Asn

405 410 415Ala Ala His Leu Asn Ile Gly Lys Gly Gly Val Asn Leu Ser Asn Gln

420 425 430Ala Ser Gly Arg Thr Leu Leu Val Glu Asn Leu Thr Gly Asn Ile Thr

435 440 445Val Asp Gly Pro Leu Arg Val Asn Asn Gln Val Gly Gly Tyr Ala Leu 450 455 460Ala Gly Ser Ser Ala Asn Phe Glu Phe Lys Ala Gly Val Asp Thr Lys465 470 475 480Asn Gly Thr Ala Thr Phe Asn Asn Asp Ile Ser Leu Gly Arg Phe Val

485 490 495Asn Leu Lys Val Asp Ala His Thr Ala Asn Phe Lys Gly Ile Asp Thr

500 505 510Gly Asn Gly Gly Phe Asn Thr Leu Asp Phe Ser Gly Val Thr Asp Lys

515 520 525Val Asn Ile Asn Lys Leu Ile Thr Ala Ser Thr Asn Val Ala Val Lys

530 535 540Asn Phe Asn Ile Asn Glu Leu Ile Val Lys Thr Asn Gly Ile Ser Val545 550 555 560Gly Glu Tyr Thr His Phe Ser Glu Asp Ile Gly Ser Gln Ser Arg Ile

565 570 575Asn Thr Val Arg Leu Glu Thr Gly Thr Arg Ser Ile Phe Ser Gly Gly

580 585 590Val Lys Phe Lys Ser Gly Glu Lys Leu Val Ile Asn Asp Phe Tyr Tyr

595 600 605Ser Pro Trp Asn Tyr Phe Asp Ala Arg Asn Val Lys Asn Val Glu Ile

610 615 620Thr Arg Lys Phe Ala Ser Ser Thr Pro Glu Asn Pro Trp Gly Thr Ser625 630 635 640Lys Leu Met Phe Asn Asn Leu Thr Leu Gly Gln Asn Ala Val Met Asp

645 650 655Tyr Ser Gln Phe Ser Asn Leu Thr Ile Gln Gly Asp Phe Ile Asn Asn

660 665 670Gln Gly Thr Ile Asn Tyr Leu Val Arg Gly Gly Lys Val Ala Thr Leu

675 680 685Asn Val Gly Asn Ala Ala Ala Met Met Phe Asn Asn Asp Ile Asp Ser

690 695 700Ala Thr Gly Phe Tyr Lys Pro Leu Ile Lys Ile Asn Ser Ala Gln Asp705 710 715 720Leu Ile Lys Asn Thr Glu His Val Leu Leu LysAla Lys Ile Ile Gly

725 730 735Tyr Gly Asn Val Ser Thr Gly Thr Asn Gly Ile Ser Asn Val Asn Leu

740 745 750Glu Glu Gln Phe Lys Glu Arg Leu Ala Leu Tyr Asn Asn Asn Asn Arg

755 760 765Met Asp Thr Cys Val Val Arg Asn Thr Asp Asp Ile Lys Ala Cys Gly

770 775 780Met Ala Ile Gly Asn Gln Ser Met Val Asn Asn Pro Asp Asn Tyr Lys785 790 795 800Tyr Leu Ile Gly Lys Ala Trp Arg Asn Ile Gly Ile Ser Lys Thr Ala

805 810 815Asn Gly Ser Lys Ile Ser Val Tyr Tyr Leu Gly Asn Ser Thr Pro Thr

820 825 830Glu Asn Gly Gly Asn Thr Thr Asn Leu Pro Thr Asn Thr Thr Asn Asn

835 840 845Ala His Ser Ala Asn Tyr Ala Leu Val Lys Asn Ala Pro Phe Ala His

850 855 860Ser Ala Thr Pro Asn Leu Val Ala Ile Asn Gln His Asp Phe Gly Thr865 870 875 880Ile Glu Ser Val Phe Glu Leu Ala Asn Arg Ser Lys Asp Ile Asp Thr

885 890 895Leu Tyr Thr His Ser Gly Ala Gln Gly Arg Asp Leu Leu Gln Thr Leu

900 905 910Leu Ile Asp Ser His Asp Ala Gly Tyr Ala Arg Gln Met Ile Asp Asn

915 920 925Thr Ser Thr Gly Glu Ile Thr Lys Gln Leu Asn Ala Ala Thr Asp Ala

930 935 940Leu Asn AsnVal Ala Ser Leu Glu His Lys Gln Ser Gly Leu Gln Thr945 950 955 960Leu Ser Leu Ser Asn Ala Met Ile Leu Asn Ser Arg Leu Val Asn Leu

965 970 975Ser Arg Lys His Thr Asn His Ile Asn Ser Phe Ala Gln Arg Leu Gln

980 985 990Ala Leu Lys Gly Gln Glu Phe Ala Ser Leu Glu Ser Ala Ala Glu Val

995 1000 1005Leu Tyr Gln Phe Ala Pro Lys Tyr Glu Lys Pro Thr Asn Val Trp Ala

1010 1015 1020Asn Ala Ile Gly Gly Ala Ser Leu Asn Ser Gly Ser Asn Ala Ser Leu1025 1030 1035 1040Tyr Gly Thr Ser Ala Gly Val Asp Ala Phe Leu Asn Gly Asn Val Glu

1045 1050 1055Ala Ile Val Gly Gly Phe Gly Ser Tyr Gly Tyr Ser Ser Phe Ser Asn

1060 1065 1070Gln Ala Asn Ser Leu Asn Ser Gly Ala Asn Asn Ala Asn Phe Gly Val

1075 1080 1085Tyr Ser Arg Phe Phe Ala Asn Gln His Glu Phe Asp Phe Glu Ala Gln

1090 1095 1100Gly Ala Leu Gly Ser Asp Gln Ser Ser Leu Asn Phe Lys Ser Thr Leu1105 1110 1115 1120Leu Gln Asp Leu Asn Gln Ser Tyr Asn Tyr Leu Ala Tyr Ser Ala Thr

1125 1130 1135Ala Arg Ala Ser Tyr Gly Tyr Asp Phe Ala Phe Phe Arg Asn Ala Leu

1140 1145 1150Val Leu Lys Pro Ser Val Gly Val Ser Tyr Asn His Leu Gly Ser Thr

1155 1160 1165Asn Phe Lys Ser Asn Ser Gln Ser Gln Val Ala Leu Lys Asn Gly Ala

1170 1175 1180Ser Ser Gln His Leu Phe Asn Ala Asn Ala Asn Val Glu Ala Arg Tyr1185 1190 1195 1200Tyr Tyr Gly Asp Thr Ser Tyr Phe Tyr Leu His Ala Gly Val Leu Gln

1205 1210 1215Glu Phe Ala His Phe Gly Ser Asn Asp Val Ala Ser Leu Asn Thr Phe

1220 1225 1230Lys Ile Asn Ala Ala Arg Ser Pro Leu Ser Thr Tyr Ala Arg Ala Met

1235 1240 1245Met Gly Gly Glu Leu Gln Leu Ala Lys Glu Val Phe Leu Asn Leu Gly

1250 1255 1260Val Val Tyr Leu His Asn Leu Ile Ser Asn Ala Ser His Phe Ala Ser1265 1270 1275 1280Asn Leu Gly Met Arg Tyr Ser Phe

1285(2) SEQ ID NO 1040 information

Sequence properties:

(A) length: 1484 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1484

(xi) sequence representation: 1040: Gly Ala Val Ser Leu Arg Gly Gln Phe Asn Leu Ser Asn Asn Ser Ser 151015 Leu Asp Phe Gln Gly Ser Ser Ala Ile Thr Ser Asn Thr Ala Phe Asn SEQ ID NO

20 25 30Phe Tyr Asp Asn Ala Phe Ser Gln Ser Pro Ile Thr Phe His Gln Ala

35 40 45Leu Asp Ile Lys Val Pro Leu Ser Leu Gly Gly Asn Leu Leu Asn Pro

50 55 60Asn Asn Ser Ser Val Leu Asn Leu Lys Asn Ser Gln Leu Val Phe Ser65 70 75 80Asp Gln Gly Ser Leu Asn Ile Ala Asn Ile Asp Leu Leu Ser Asp Leu

85 90 95Asn Gly Asn Lys Asn Arg Val Tyr Asn Ile Ile Gln Ala Asp Met Asn

100 105 110Gly Asn Trp Tyr Glu Arg Ile Asn Phe Phe Gly Met Arg Ile Asn Asp

115 120 125Gly Ile Tyr Asp Ala Lys Asn Gln Thr Tyr Ser Phe Thr Asn Pro Leu

130 135 140Asn Asn Ala Leu Lys lle Thr Glu Ser Phe Lys Asn Asn Gln Leu Ser145 150 155 160Val Thr Leu Ser Gln Ile Pro Gly Ile Lys Asn Thr Leu Tyr Asn Ile

165 170 175Gly Ser Glu Ile Phe Asn Tyr Gln Lys Val Tyr Asn Asn Ala Asn Gly

180 185 190Val Tyr Ser Tyr Ser Asp Asp Ala Gln Gly Val Phe Tyr Leu Thr Ser

195 200 205Ser Val Lys Gly Tyr Tyr Asn Pro Asn Gln Ser Tyr Gln Ala Ser Gly

210 215 220Ser Asn Asn Thr Thr Lys Asn Asn Asn Leu Thr Ser Glu Ser Ser Val225 230 235 240Ile Ser Gln Thr Tyr Asn Ala Gln Gly Asn Pro Ile Ser Ala Leu His

245 250 255Val Tyr Asn Lys Gly Tyr Asn Phe Ser Asn Ile Lys Ala Leu Gly Gln

260 265 270Met Ala Leu Lys Leu Tyr Pro Glu Ile Lys Lys Ile Leu Gly Asn Asp

275 280 285Phe Ser Leu Ser Ser Leu Ser Asn Leu Lys Gly Asp Ala Leu Asn Gln

290 295 300Leu Thr Lys Leu Ile Thr Pro Ser Asp Trp Lys Asn Ile Asn Glu Leu305 310 315 320Ile Asp Asn Ala Asn Asn Ser Val Val Gln Asn Phe Asn Asn Gly Thr

325 330 335Leu Ile Ile Gly Ala Thr Lys Ile Gly Gln Thr Asp Thr Asn Ser Ala

340 345 350Val Val Phe Gly Gly Leu Gly Tyr Gln Lys Pro Cys Asp Tyr Thr Asp

355 360 365Ile Val Cys Gln Lys Phe Arg Gly Thr Tyr Leu Gly Gln Leu Leu Glu

370 375 380Ser Ile Ser Ala Asp Leu Gly Tyr Ile Asp Thr Thr Phe Asn Ala Lys385 390 395 400Glu Ile Tyr Leu Thr Gly Thr Leu Gly Ser Gly Asn Ala Trp Gly Thr

405 410 415Gly Gly Ser Ala Ser Val Thr Phe Asn Ser Gln Thr Ser Leu Ile Leu

420 425 430Asn Gln Ala Asn Ile Val Ser Ser Gln Thr Asp Gly Ile Phe Ser Met

435 440 445Leu Gly Gln Glu Gly Ile Asn Lys Val Phe Asn Gln Ala Gly Leu Ala

450 455 460Asn Ile Leu Gly Glu Val AlaMet Gln Ser Ile Asn Lys Ala Gly Gly465 470 475 480Leu Gly Asn Leu Ile Val Asn Thr Leu Gly Ser Asp Ser Val Ile Gly

485 490 495Gly Tyr Leu Thr Pro Glu Gln Lys Asn Gln Thr Leu Ser Gln Leu Leu

500 505 510Gly Gln Asn Asn Phe Asp Asn Leu Met Asn Asp Ser Gly Leu Asn Thr

515 520 525Ala Ile Lys Asp Leu Ile Arg Gln Lys Leu Gly Phe Trp Thr Gly Leu

530 535 540Val Gly Gly Leu Ala Gly Leu Gly Gly Ile Asp Leu Gln Asn Pro Glu545 550 555 560Lys Leu Ile Gly Ser Met Ser Ile Asn Asp Leu Leu Ser Lys Lys Gly

565 570 575Leu Phe Asn Gln Ile Thr Gly Phe Ile Ser Ala Asn Asp Ile Gly Gln

580 585 590Val Ile Ser Val Met Leu Gln Asp Ile Val Lys Pro Ser Asp Ala Leu

595 600 605Lys Asn Asp Val Ala Ala Leu Gly Lys Gln Met Ile Gly Glu Phe Leu

610 615 620Gly Gln Asp Thr Leu Asn Ser Leu Glu Ser Leu Leu Gln Asn Gln Gln625 630 635 640Ile Lys Ser Val Leu Asp Lys Val Leu Ala Ala Lys Gly Leu Gly Ser

645 650 655Ile Tyr Glu Gln Gly Leu Gly Asp Leu Ile Pro Asn Leu Gly Lys Lys

660 665 670Gly Ile Phe Ala Pro Tyr Gly Leu Ser Gln Val Trp Gln Lys Gly Asp

675 680 685Phe Ser Phe Asn Ala Gln Gly Asn Val Phe Val Gln Asn Ser Thr Phe

690 695 700Ser Asn Ala Asn Gly Gly Thr Leu Ser Phe Asn Ala Gly Asn Ser Leu705 710 715 720Ile Phe Ala Gly Asn Asn His Ile Ala Phe Thr Asn His Ser Gly Thr

725 730 735Leu Asn Leu Leu Ser Asn Gln Val Ser Asn Ile Asn Val Thr Met Leu

740 745 750Asn Ala Ser Asn Gly Leu Lys Ile Asn Ala Thr Asn Asn Asn Val Ser

755 760 765Val Ser Gln Gly Asn Leu Phe Ile Asn Ala Ser Cys Val Gln Gln Ser

770 775 780Asp Pro Thr Thr Ala Ser Ala Thr Asn Pro Cys Thr Thr Ala Gln Asn785 790 795 800Asn Ala Ser Ser Ser Asn Ala Ser Asn Asn Ala Pro Ile Ala Leu Asn

805 810 815Asn Asn Asp Glu Ser Leu Val Val Thr Ala Asn Gly Phe Asn Phe Ser

820 825 830Gly Asn Ile Tyr Ala Asn Gly Val Val Asp Phe Ser Lys Ile Lys Gly

835 840 845Ser Ala Asn Val Lys Asn Leu Tyr Leu Tyr Asn Asn Ala Gln Phe Gln

850 855 860Ala Asn Asn Leu Thr Ile Ser Asn Gln Ala Val Leu Glu Lys Asn Ala865 870 875 880Ser Phe Val Thr Asn Asn Leu Asn Ile Gln Gly Ala Phe Asn Asn Asn

885 890 895Ala Thr Gln Lys Ile Glu Val Leu Gln Asn Leu Val Ile Ala Ser Asn

900 905 910Ala Ser Leu Ser Thr Gly Ile Tyr Gly Leu Glu Val Gly Gly Ala Leu

915 920 925Asn Asn Leu Gly Ala Ile His Phe Asn Leu Glu Asn Ser Gln Thr Pro

930 935 940Val Asn Pro Leu Ile Gln Val Gly Gly Ile Ile Asn Leu Asn Thr Thr945 950 955 960Gln Thr Pro Phe Met Asn Val Ser Val Ala Asn Gly Gly Thr Tyr Thr

965 970 975Leu Leu Lys Ser Ser Arg Tyr Ile Asp Tyr Asn Ile Asn Pro Asn Ser

980 985 990Leu Gln Ser Tyr Leu Lys Leu Tyr Thr Leu Ile Asn Ile Asn Gly Asn

995 1000 1005His Ile Glu Glu Lys Asn Gly Val Leu Thr Tyr Leu Gly Gln Arg Val

1010 1015 1020Leu Leu Gln Asp Lys Gly Leu Leu Leu Ser Val Ala Leu Pro Asn Ser1025 1030 1035 1040Asn Asn Ala Ser Gln Asn Asn Ile Leu Ser Leu Ser Val Leu His Asn

1045 1050 1055Gln Ile Lys Met Ser Tyr Gly Asn Lys Val Met Asp Phe Thr Pro Pro

1060 1065 1070Thr Leu Gln Asp Tyr Ile Val Gly Ile Gln Gly Gln Ser Ala Leu Asn

1075 1080 1085Gln Ile Glu Ala Val Gly Gly Asn Asn Ala Ile Lys Trp Leu Ser Thr

1090 1095 1100Leu Met Met Glu Thr Lys Glu Asn Pro Leu Phe Ala Pro Ile Tyr Leu1105 1110 1115 1120Glu Asn His Ser Leu Asn Glu Ile Leu Gly Val Thr Lys Asp Leu Gln

1125 1130 1135Asn Thr Ala Ser Leu Ile Ser Asn Pro Asn Phe Arg Asn Asn Ala Thr

1140 1145 1150Ser Leu Leu Glu Met Ala Ser Tyr Thr Gln Gln Thr Ser Arg Leu Thr

1155 1160 1165Lys Leu Ser Asp Phe Arg Ala Arg Glu Gly Glu Ser Asn Phe Ser Glu

1170 1175 1l80Arg Leu Leu Glu Leu Lys Asn Lys Arg Phe Ser Asp Pro Asn Pro Ser1185 1190 1195 1200Glu Val Phe Val Lys Tyr Ser Gln Leu Ser Lys His Pro Asn Asn Leu

1205 1210 1215Trp Ile Gln Gly Val Gly Gly Ala Ser Phe Ile Ser Gly Gly Asn Gly

1220 1225 1230Thr Leu Tyr Gly Leu Asn Val Gly Tyr Asp Arg Leu Val Lys Ser Val

1235 1240 1245Ile Leu Gly Gly Tyr Val Ala Tyr Gly Tyr Ser Gly Phe Asn Gly Asn

1250 1255 1260Ile Met His Ser Leu Ala Asn Asn Val Asp Val Gly Met Tyr Ala Arg1265 1270 1275 1280Ala Phe Leu Lys Arg Asn Glu Phe Thr Leu Ser Ala Asn Glu Thr Tyr

1285 1290 1295Gly Gly Asn Ala Ser His Ile Asn Ser Ser Asn Ser Leu Leu Ser Val

1300 1305 1310Leu Asn Gln Arg Tyr Asn Tyr Asn Thr Trp Thr Thr Ser Val Asn Gly

1315 1320 1325Asn Tyr Gly Tyr Asp Phe Met Phe Lys Gln Lys Ser Val Val Leu Lys

1330 1335 1340Pro Gln Val Gly Leu Ser Tyr His Phe Ile Gly Leu Ser Gly Met Lys1345 1350 1355 1360Gly Lys Met Gln Asn Pro Ala Tyr Gln Gln PheVal Met His Ser Asn

1365 1370 1375Pro Ser Asn Glu Ser Val Leu Thr Leu Asn Met Gly Leu Glu Ser Arg

1380 1385 1390Lys Tyr Phe Gly Lys Asn Ser Tyr Tyr Phe Val Thr Ala Arg Leu Gly

1395 1400 1405Arg Asp Leu Leu Ile Lys Ala Lys Gly Asp Asn Val Val Arg Phe Val

1410 1415 1420Gly Glu Asn Thr Leu Leu Tyr Arg Lys Gly Glu Ile Phe Asn Thr Phe1425 1430 1435 1440Ala Ser Val Ile Thr Gly Gly Glu Met His Leu Trp Arg Leu Met Tyr

1445 1450 1455Val Asn Ala Gly Val Gly Leu Lys Met Gly Leu Gln Tyr Gln Asp Leu

1460 1465 1470Asn Ile Thr Gly Asn Val Gly Met Arg Val Ala Phe

14751480 (2) SEQ ID NO 1041 message

Sequence properties:

(A) length: 300 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...300

(xi) sequence representation: SEQ ID NO 1041 Mer Arg Lys Thr Ile Ser Ala Leu Phe Leu Ser Ala Cys Ile Gly Leu 151015 Ser Ser Val His Ala Ser Asn Ala Leu Ile Leu Gln Thr Asp Phe Ser

20 25 30Leu Lys Asp Gly Ala Val Ser Ala Met Lys Gly Val Ala Phe Ser Val

35 40 45Asp Ser Asn Leu Lys Ile Phe Asp Leu Thr His Glu Ile Pro Pro Tyr

50 55 60Asn Ile Trp Glu Gly Ala Tyr Arg Leu Tyr Gln Thr Ala Ser Tyr Trp65 70 75 80Pro Lys Gly Ser Val Phe Val Ser Val Val Asp Pro Gly Val Gly Thr

85 90 95Asn Arg Lys Ser Val Val Leu Lys Thr Lys Asn Gly Gln Tyr Phe Val

100 105 110Ser Pro Asp Asn Gly Thr Leu Thr Leu Val Ala Gln Thr Leu Gly Ile

115 120 125Asp Ser Val Arg Glu Ile Asp Glu Lys Ala Asn Arg Leu Lys Gly Ser 130 135 140Glu Lys Ser Tyr Thr Phe His Gly Arg Asp Val Tyr Ala Tyr Thr Gly145 150 155 160Ala Arg Leu Ala Ser Gly Ala Ile Thr Phe Glu Gln Val Gly Pro Glu

165 170 175Leu Pro Ile Lys Val Val Glu Ile Pro Tyr Gln Lys Ala Lys Ala Thr

180 185 190Lys Gly Gly Val Lys Gly Asn Ile Pro Ile Leu Asp Ile Gln Tyr Gly

195 200 205Asn Val Trp Ser Asn Ile Ser Asp Lys Leu Leu Asn Gln Ala Gly Ile

210 215 220Lys Arg Asn Asp Thr Val Cys Val Thr Ile Phe Lys Asn Ser Lys Lys225 230 235 240Gln Tyr Glu Gly Lys Met Pro Tyr Val Ala Ser Phe Gly Asp Val Pro

245 250 255Glu Gly Gln Pro Leu Val Tyr Leu Asn Ser Leu Leu Asn Val Ser Val

260 265 270Ala Leu Asn Met Asp Asn Phe Ala Gln Lys His Gln Ile Lys Ser Gly

275 280 285Ala Asp Trp Asn Ile Asp Ile Lys Lys Cys Ala Lys

290295300 (2) SEQ ID NO:1042 information

Sequence properties:

(A) length: 526 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...526

(xi) sequence representation: 1042: Met Lys Leu Phe Asn Pro Arg Leu Ile Val Phe Ile Phe Ala Leu Leu 151015 Leu Gly Val Gly Phe Ser Val Pro Ser Leu Leu Glu Thr Lys Gly Pro SEQ ID NO

20 25 30Lys Ile Thr Leu Gly Leu Asp Leu Arg Gly Gly Leu Asn Met Leu Leu

35 40 45Gly Val Gln Thr Asp Glu Ala Leu Lys Asn Lys Tyr Leu Ser Leu Ala

50 55 60Ser Ala Leu Glu Tyr Asn Ala Lys Lys Gln Asn Ile Leu Leu Lys Asp65 70 75 80Ile Lys Ser Ser Leu Glu Gly Ile Ser Phe Glu Leu Leu Asp Glu Asp

85 90 95Glu Ala Lys Lys Leu Asp Ala Leu Leu Leu Glu Leu Gln Gly His Ser

100 105 110Gln Phe Glu Ile Lys Lys Glu Ala Glu Phe Tyr Ser Val Lys Leu Thr

115 120 125Pro Leu Glu Gln Glu Glu Leu Arg Lys Asn Thr Ile Leu Gln Val Ile

130 135 140Gly Ile Ile Arg Asn Arg Leu Asp Gln Phe Gly Leu Ala Glu Pro Val145 150 155 160Val Ile Gln Gln Gly Arg Glu Glu Ile Ser Val Gln Leu Pro Gly Ile

165 170 175Lys Thr Leu Glu Glu Glu Arg Arg Ala Lys Asp Leu Ile Ser Lys Ser

180 185 190Ala His Leu Gln Met Met Ala Val Asp Glu Glu His Asn Lys Asp Ala

195 200 205Met Asn Met Thr Asp Leu Glu Ala Gln Lys Leu Gly Ser Val Leu Leu

210 215 220Ser Asp Ala Glu Met Gly Gly Lys Ile Leu Leu Lys Ala Ile Pro Ile225 230 235 240Leu Asp Gly Glu Met Leu Thr Asp Ala Lys Val Val Tyr Asp Gln Asn

245 250 255Asn Gln Pro Val Val Ser Phe Thr Leu Asp Ala Gln Gly Ala Lys Ile

260 265 270Phe G1y Asp Phe Ser Gly Ala Asn Val Gly Lys Arg Met Ala Ile Val

275 280 285Leu Asp Asn Lys Val Tyr Ser Ala Pro Val Ile Arg Glu Arg Ile Gly

290 295 300Gly Gly Ser Gly Gln Ile Asn Gly Asn Phe Ser Val Ala Gln Ala Ser305310 315 320Asp Leu Ala Ile Ala Leu Arg Ser Gly Ala Met Asn Ala Pro Ile Gln

325 330 335Val Leu Glu Lys Arg Ile Val Gly Pro Ser Leu Gly Lys Asp Ser Ile

340 345 350Lys Thr Ser Ile Ile Ala Leu Val Gly Gly Phe Ile Leu Val Met Gly

355 360 365Phe Met Ala Leu Tyr Tyr Ser Met Ala Gly Val Ile Ala Cys Met Ala

370 375 380Leu Val Val Asn Leu Phe Leu Ile Val Ala Val Met Ala Ile Phe Gly385 390 395 400Ala Thr Leu Thr Leu Pro Gly Met Ala Gly Ile Val Leu Thr Val Gly

405 410 415Ile Ala Val Asp Ala Asn Ile Ile Ile Asn Glu Arg Ile Arg Glu Val

420 425 430Leu Arg Glu Gly Glu Gly Val Val Lys Ala Ile His Leu Gly Tyr Ile

435 440 445Asn Ala Ser Arg Ala Ile Phe Asp Ser Asn Ile Thr Ser Leu Ile Ala

450 455 460Ser Val Leu Leu Tyr Ala Tyr Gly Thr Gly Ala Ile Lys Gly Phe Ala465 470 475 480Leu Thr Thr Gly Ile Gly Ile Leu Ala Ser Ile Ile Thr Ala Ile Ile

485 490 495Gly Thr Gln Gly Ile Tyr Gln Ala Leu Leu Pro Lys Leu Ala Gln Thr

500 505 510Lys Ser Leu Tyr Phe Trp Phe Gly Val Lys Asn Lys Arg Ala

515520525 (2) information SEQ ID NO 1043

Sequence properties:

(A) length:793 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...793

(xi) sequence representation: SEQ ID NO 1043 Ile Met Asn Gly Tyr Leu Arg Val Lys Thr Pro Tyr Phe Leu Ala Ser 151015 Val Val Leu Thr Phe Trp Thr Phe Asn Ser Phe Met Ser Ala Lys Asp

20 25 30Lys His His Phe Leu Lys Lys Val Thr Thr Thr Glu Gln Lys Phe Ser

35 40 45Ser Ser Ala Pro Ile Ser Trp Gln Ser Glu Glu Val Arg Asn Ser Thr

50 55 60Ser Ser Arg Thr Val Ile Ser Asn Lys Glu Leu Lys Lys Thr Gly Asn65 70 75 80Leu Asn Ile Glu Asn Ala Leu Gln Asn Val Pro Gly Ile Gln Ile Arg

85 90 95Asp Ala Thr Gly Thr Gly Val Leu Pro Lys Ile Ser Val Arg Gly Phe

100 105 110Gly Gly Gly Gly Asn Gly His Ser Asn Thr Asn Met Ile Leu Val Asn

115 120 125Gly Ile Pro Ile Tyr Gly Ala Pro Tyr Ser Asn Ile Glu Leu Ala Ile

130 135 140Phe Pro Val Thr Phe Gln Ser Val Asp Arg Ile Asp Val Ile Lys Gly145 150 155 160Gly Thr Ser Val Gln Tyr Gly Pro Asn Thr Phe Gly Gly Val Val Asn

165 170 175Val Ile Thr Lys Glu Ile Pro Lys Glu Trp Glu Asn Gln Ala Ala Glu

180 185 190Arg Ile Thr Phe Trp Gly Arg Ser Ser Asn Gly Asn Phe Val Asp Pro

195 200 205Lys Glu Lys Gly Lys Pro Leu Ala Gln Thr Leu Gly Asn Gln Met Leu

210 215 220Phe Asn Thr Tyr Gly Arg Thr Ala Gly Met Leu Gly Lys Tyr Ile Gly225 230 235 240Ile Ser Ala Gln Gly Asn Trp Ile Asn Gly Gln Gly Phe Arg Gln Asn

245 250 255Ser Pro Thr Lys Val Gln Asn Tyr Leu Leu Asp Ala Ile Tyr Lys Ile

260 265 270Asn Ala Thr Asn Thr Phe Lys Ala Tyr Tyr Gln Tyr Tyr Gln Tyr Asn

275 280 285Ser Tyr His Pro Gly Thr Leu Ser Ala Gln Asp Tyr Ala Tyr Asn Arg

290 295 300Phe Ile Asn Glu Arg Pro Asp Asn Gln Asp Gly Gly Arg Ala Lys Arg305 310 315 320Phe Gly Ile Val Tyr Gln Asn Tyr Phe Gly Asp Pro Asp Arg Lys Val

325 330 335Gly Gly Asp Phe Lys Phe Thr Tyr Phe Thr His Asp Met Ser Arg Asp

340 345 350Phe Gly Phe Ser Asn Gln Tyr Gln Ser Val Tyr Met Ser Gly Gln Asn

355 360 365Lys Ile Leu Pro Phe Lys Gly Lys Gly Glu Ile Ser Ala Lys Asn Pro

370375 380Asn Cys Gly Leu Tyr Ser Tyr Ser Asp Thr Asn Ser Pro Cys Trp Gln385 390 395 400Phe Phe Asp Asn Ile Arg Arg Ser Val Val Asn Ala Phe Glu Pro Lys

405 410 415Leu Asn Leu Ile Val Asn Thr Gly Lys Val Lys Gln Thr Phe Asn Met

420 425 430Gly Met Arg Phe Leu Thr Glu Asp Leu Tyr Arg Arg Ser Thr Thr Arg

435 440 445Lys Asn Pro Ser Met Pro Asn Asn Gly Ser Gly Phe Asp Ala Gly Thr

450 455 460Ser Leu Asn Asn Phe Asn Asn Tyr Thr Ala Val Tyr Ala Ser Asp Glu465 470 475 480Ile Asn Phe Asn Asn Gly Met Leu Thr Ile Thr Pro Gly Leu Arg Tyr

485 490 495Thr Phe Leu Asn Tyr Glu Lys Lys Asp Ala Pro Pro Phe Lys Val Gly

500 505 510Gln Thr Pro Lys Thr Thr Lys Glu Arg Tyr Asn Gln Trp Asn Pro Ala

515 520 525Val Asn Val Gly Tyr Lys Pro Ile Lys Glu Leu Leu Phe Tyr Phe Asn

530 535 540Tyr Gln Arg Ser Tyr Ile Pro Pro Gln Phe Ser Asn Ile Gly Asn Phe545 550 555 560Val Gly Thr Ser Thr Asp Tyr Phe Gln Ile Phe Asn Val Met Glu Gly

565 570 575Gly Ser Arg Tyr Tyr Phe Asn His Gln Val Ser Phe Asn Ala Asn Tyr

580 585 590Phe Val Ile Phe Ala Asn His Tyr Phe Thr Gly Arg Tyr Gly Asp Asn

595 600 605Arg Glu Pro Val Asn Ala Arg Ser Gln Gly Val Glu Leu Glu Leu Tyr

610 615 620Tyr Thr Pro Ile Arg Gly Leu Asn Phe His Ala Ala Tyr Thr Phe Ile625 630 635 640Asp Ala Asn Ile Thr Ser His Thr Met Val Thr Asn Pro Ala Asn Pro

645 650 655Lys Gly Pro Lys Lys Asp Ile Phe Gly Lys Lys Leu Pro Phe Val Ser

660 665 670Pro His Gln Phe Ile Leu Asp Ala Sar Tyr Thr Tyr Ala Lys Thr Thr

675 680 685Ile Gly Leu Ser Ser Phe Phe Tyr Ser Arg Ala Tyr Ser Asp Val Leu

690 695 700Asn Thr Val Pro Phe Thr Glu Tyr Ala Pro Thr Ile Lys Asn Gly Ala705 710 715 720Ile Val Thr Lys Thr Ala Gly Met Thr Pro Tyr Tyr Trp Val Trp Asn

725 730 735Leu Gln Ile Ser Thr Thr Leu Trp Glu Arg Lys Asn Gln Ser Val Asn

740 745 750Ala Ser Leu Gln Ile Asn Asn Ile Phe Asn Met Lys Tyr Trp Phe Ser

755 760 765Gly Ile Gly Thr Ser Pro Asn Gly Lys Glu Ala Ala Pro Pro Arg Ser

770775780 Ile Thr Ala Tyr Val Ser Tyr Asn Phe 785790 (2) SEQ ID NO:1044 information

Sequence properties:

(A) length: 333 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...333

(xi) sequence representation: SEQ ID NO:1044: Met Leu Ile Ala Arg Phe Lys Lys Ala Leu Ile Ser Tyr Ser Leu Gly 151015 Val Leu Leu Val Ser Ser Leu Leu Gly Val Ala Asn Ala Ser Asn Gln

20 25 30Glu Ile Gln Val Lys Asp Tyr Phe Gly Glu Gln Thr Ile Lys Leu Pro

35 40 45Val Ser Lys Ile Ile Tyr Leu Gly Ser Phe Ala Glu Val Pro Ala Met

50 55 60Phe Asn Thr Trp Asp Arg Val Val Gly Ile Ser Asp Tyr Ala Phe Lys65 70 75 80Ser Asp Ile Val Lys Ala Thr Leu Lys Asp Pro Glu Arg Ile Lys Pro

85 90 95Met Ser Ser Asp His Val Ala Ala Leu Asn Val Glu Leu Leu Lys Lys

100 105 110Leu Ser Pro Asp Leu Val Val Thr Phe Val Gly Asn Pro Lys Ala Val

115 120 125Glu His Ala Lys Lys Phe Gly Ile Ser Phe Leu Ser Phe Gln Glu Lys

130 135 140Thr Ile Val Glu Val Met Glu Asp Ile Asp Ala Gln Ala Lys Ala Leu145 150 155 160Glu Val Asp Ala Ser Lys Lys Leu Ala Lys Mer Gln Glu Thr Leu Asp

165 170 175Phe Ile Lys Glu Arg Leu Lys Asn Val Lys Lys Lys Lys Gly Val Glu

180 185 190Leu Phe His Lys Ala Asn Lys Ile Ser Gly His Gln Ala Leu Asp Ser

195 200 205Asp Ile Leu Glu Lys Gly Gly Ile Asp Asn Phe Gly Leu Lys Tyr Val

210 215 220Lys Phe Gly Arg Ala Asp Ile Ser Val Glu Lys Ile Val Lys Glu Asn225 230 235 240Pro Glu Ile Ile Phe Ile Trp Trp Ile Ser Pro Leu Ser Pro Glu Asp

245 250 255Val Leu Asn Asn Pro Lys Phe Ser Thr Ile Lys Ala Ile Lys Asn Lys

260 265 270Gln Val Tyr Lys Leu Pro Thr Met Asp Ile Gly Gly Pro Arg Ala Pro

275 280 285Leu Ile Ser Leu Phe Ile Ala Leu Lys Ala His Pro Glu Ala Phe Lys

290 295 300Gly Val Asp Ile Asn Ala Ile Ile Lys Asp Tyr Tyr Lys Val Val Phe305 310 315 320Asp Leu Asn Asp Ala Glu Val Glu Pro Phe Leu Trp His

325330 (2) SEQ ID NO 1045 information

Sequence properties:

(A) length: 400 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...400

(xi) sequence representation: SEQ ID NO 1045: Met Tyr Lys Leu Gly Ile Phe Leu Leu Ala Thr Leu Leu Ser Ala Asn 151015 Thr Gln Lys Val Ser Asp Ile Ala Lys Asp Ile Gln His Lys Glu Thr

20 25 30Leu Leu Lys Lys Thr His Glu Glu Lys Asn Gln Leu Asn Ser Arg Leu

35 40 45Ser Ser Leu Gly Glu Ala Ile ArG Ser Lys Glu Leu Gln Lys Val Glu

50 55 60Ile Glu Arg Gln Met Val Ala Leu Lys Lys Ser Leu Glu Lys Asn Arg65 70 75 80Asn Glu Ser Leu Val Gln Glu Lys Val Leu Thr Asn Tyr Arg Lys Ser

85 90 95Leu Asp His Leu Gln Lys Gln Arg Ser Phe Leu Gln Lys Arg Val Phe

100 105 110Asp Thr Leu Leu Glu Asp Phe Leu Phe Ser Gln Ala Leu Lys Gly Gln

115 120 125Asn Leu Ala Ser Ser Asn Asp Val Ile Leu Gln Val Ala Phe Glu Asn

130 135 140Leu His Gln Ser Thr Leu Ser Lys Met Ser Gln Leu Ser Gln Glu Glu145 150 155 160Lys Lys Leu Asn Val Gln Ala Leu Glu Val Lys Ser Ser Ile Gln Lys

165 170 175Ile Ser Ser Val Ile Asp Glu Gln Lys Thr Arg Glu Ser Thr Leu Lys

180 185 190Ser Leu Gln Thr Glu Gln Asn Lys Leu Ile Leu Ser Met Gln Lys Asp

195 200 205Tyr Ala Ile Tyr Asn Gln Arg Leu Ser Leu Leu Glu Lys Glu Arg Gln

210 215 220Asn Leu Asn Ala Leu Leu Lys Arg Leu Asn Ile Ile Lys Gln Asn Arg225 230 235 240Glu Asn Glu Glu Arg Val Ser Leu Lys Lys Ser Ser Gln Ala Leu Glu

245 250 255Val Lys Gln Val Ala Ser Ser Tyr Gln Asn Ile Asn Thr Thr Ser Tyr

260 265 270Asn Gly Pro Lys Thr Ile Ala Pro Leu Asn Asp Tyr Glu Val Val Gln

275 280 285Lys Phe Gly Pro Tyr Ile Asp Pro Val Tyr Asn Leu Lys Ile Phe Ser

290 295 300Glu Ser Ile Thr Leu Val Ser Lys Thr Pro Asn Ala Leu Val Arg Asn305 310 315 320Val Leu Asp Gly Lys Ile Val Phe Ala Lys Glu Ile Asn Met Leu Lys

325 330 335Lys Val Val Ile Ile Glu His Lys Asn Gly Ile Arg Thr Ile Tyr Ser

340 345 350Gln Leu Asp Lys Ile Ala Pro Thr Ile Lys Ser Gly Met Arg Ile Gln

355 360 365Lys Gly Tyr Val Leu Gly Arg Ile Asp Gln Arg Leu Gly Phe Glu Val

370375380 Thr Met Arg Glu Lys His Ile Asn Pro Leu Glu Leu Ile Ala Arg Asn 385390395400 (2) information SEQ ID NO:1046

Sequence properties:

(A) length: 549 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...549

(xi) sequence representation: SEQ ID NO 1046: Met Asp Lys Asn Asn Asn Asn Asn Leu Arg Leu Ile Leu Ala Ile Ala 151015 Leu Ser Phe Leu Phe Ile Ala Leu Tyr Ser Tyr Phe Phe Gln Glu Pro

20 25 30Asn Lys Thr Thr Thr Glu Thr Thr Lys Gln Glu Thr Thr Asn Asn His

35 40 45Thr Ala Thr Ser Pro Thr Ala Ser Asn Thr Ile Thr Gln Asp Phe Ser

50 55 60Val Thr Gln Thr Ile Pro Gln Glu Ser Leu Leu Ser Thr Ile Ser Phe65 70 75 80Glu His Ala Lys Ile Glu Ile Asp Ser Leu Gly Arg Ile Lys Gln Val

85 90 95Tyr Leu Lys Asp Lys Lys Tyr Leu Thr Pro Lys Glu Lys Gly Phe Leu

l00 105 110Glu His Val Ser His Leu Phe Ser Ser Lys Glu Asn Ser Gln Pro Ser

115 120 125Leu Lys Glu Leu Pro Leu Leu Ala Ala Asp Lys Leu Lys Pro Leu Glu

130 135 140Val Arg Phe Leu Asp Pro Thr Leu Asn Asn Lys Ala Phe Asn Thr Pro145 150 155 160Tyr Ser Ala Ser Lys Thr Thr Leu Gly Pro Asn Glu Gln Leu Val Leu

165 170 175Thr Gln Asp Leu Gly Thr Leu Ser Ile Ile Lys Thr Leu Thr Phe Tyr

180 185 190Asp Asp Leu His Tyr Asp Leu Lys Ile Ala Phe Lys Ser Pro Asn Asn

195 200 205Leu Ile Pro Ser Tyr Val Ile Thr Asn Gly Tyr Arg Pro Val Ala Asp

210 215 220Leu Asp Ser Tyr Thr Phe Ser Gly Val Leu Leu Glu Asn Thr Asp Lys225 230 235 240Lys Ile Glu Lys Ile Glu Asp Lys Asp Ala Lys Glu Ile Lys Arg Phe

245 250 255Ser Asn Thr Leu Phe Leu Ser Ser Val Asp Arg Tyr Phe Thr Thr Leu

260 265 270Leu Phe Thr Lys Asp Pro Gln Gly Phe Glu Ala Leu Ile Asp Ser Glu

275 280 285Ile Gly Thr Lys Asn Pro Leu Gly Phe Ile Ser Leu Lys Asn Glu Ala

290 295 300Asn Leu His Gly Tyr Ile Gly Pro Lys Asp Tyr Arg Ser Leu Lys Ala305 310 315 320Ile Ser Pro Met Leu Thr Asp Val Ile Glu Tyr Gly Leu Ile Thr Phe

325 330 335Phe Ala Lys Gly Val Phe Val Leu Leu Asp Tyr Leu Tyr Gln Phe Val

340 345 350Gly Ash Trp Gly Trp Ala Ile Ile Leu Leu Thr Ile Ile Val Arg Ile

355 360 365Ile Leu Tyr Pro Leu Ser Tyr Lys Gly Met Val Ser Met Gln Lys Leu

370 375 380Lys Glu Leu Ala Pro Lys Met Lys Glu Leu Gln Glu Lys Tyr Lys Gly385 390 395 400Glu Pro Gln Lys Leu Gln Ala His Met Met Gln Leu Tyr Lys Lys His

405 410 415Gly Ala Asn Pro Leu Gly Gly Cys Leu Pro Leu Ile Leu Gln Ile Pro

420 425 430Val Phe Phe Ala Ile Tyr ArG Val Leu Tyr Asn Ala Val Glu Leu Lys

435 440 445Ser Ser Glu Trp Val Leu Trp Ile His Asp Leu Ser Ile Met Asp Pro

450 455 460Tyr Phe Ile Leu Pro Leu Leu Met Gly Ala Ser Met Tyr Trp His Gln465 470 475 480Ser Val Thr Pro Asn Thr Met Thr Asp Pro Met Gln Ala Lys Ile Phe

485 490 495Lys Leu Leu Pro Leu Leu Phe Thr Ile Phe Leu Ile Thr Phe Pro Ala

500 505 510Gly Leu Val Leu Tyr Trp Thr Thr His Asn Ile Leu Ser Val Leu Gln

515 520 525Gln Leu Ile Ile Asn Lys Val Leu Glu Asn Lys Lys Arg Ala His Ala

530535540 Gln Asn Ile Lys Glu545(2) SEQ ID NO 1047 message

Sequence properties:

(A) length: 479 an amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 479

(xi) sequence representation: SEQ ID NO 1047: Met Lys Lys Ser Leu Cys Leu Ser Phe Phe Leu Thr Phe Ser Asn Pro 151015 Leu Gln Ala Leu Val Ile Glu Leu Leu Glu Glu Ile Lys Thr Ser Pro

20 25 30His Lys Gly Thr Phe Lys Ala Lys Val Leu Asp Ser Lys Glu Pro Arg

35 40 45Gln Val Leu Gly Val Tyr Asn Ile Ser Pro His Lys Lys Leu Thr Leu

50 55 60Thr Ile Thr His Ile Ser Thr Ala I1e Val Tyr Gln Pro Leu Asp Glu65 70 75 80Lys Leu Ser Leu Glu Thr Thr Leu Ser Pro Asn Arg Pro Thr Ile Pro

85 90 95Arg Asn Thr Gln Ile Val Phe Ser Ser Lys Glu Leu Lys Glu Pro His

100 105 110Ser Asn Pro Ile Pro Ser Leu Asn Ala Pro Met Gln Lys Pro Gln Asn

115 120 125Lys Pro Ser Ser Ser Gln Gln Ser Pro Gln Asn Phe Ser Tyr Pro Glu

130 135 140Ser Lys Leu Gly Ser Lys Asn Ser Lys Asn Ser Leu Leu Gln Pro Leu145 150 155 160Val Thr Pro Ser Lys Val Ser Pro Thr Asn Glu Val Lys Thr Pro Thr

165 170 175Asn Asp Ala Asn Pro Pro Leu Lys His Ser Ser Gln Asp Gln Glu Asn

180 185 190Asn Leu Phe Val Ala Pro Pro Thr Glu Lys Thr Leu Pro Asn Asn Thr

195 200 205Ser Ser Ala Asp Ala Ser Glu Asn Asn Glu Ser Asn Glu Asn Arg Asp

210 215 220Asn Val Glu Lys Gln Ala Ile Arg Asp Pro Asn Ile Lys Glu Phe Ala225 230 235 240Cys Gly Lys Trp Val Tyr AspAsp Glu Asn Leu Gln Ala Tyr Arg Pro

245 250 255Ser Ile Leu Lys Arg Val Asp Lys Asp Lys Glu Ile Thr Thr Asp Ile

260 265 270Thr Pro Cys Asp Tyr Ser Thr Ala Glu Asn Lys Ser Gly Lys Ile Ile

275 280 285Thr Pro Tyr Thr Lys Ile Ser Val His Lys Thr Glu Pro Leu Glu Asp

290 295 300Pro Gln Thr Phe Glu Ala Lys Asn Asn Phe Ala Ile Leu Gln Ala Arg305 310 315 320Ser Ser Thr Glu Lys Cys Lys Arg Ala Arg Ala Arg Lys Asp Gly Thr

325 330 335Thr Arg Gln Cys Tyr Leu Ile Glu Glu Pro Leu Lys Gln Ala Trp Glu

340 345 350Ser Glu Tyr Glu Ile Thr Thr Gln Leu Val Lys Ala Ile Tyr Glu Arg

355 360 365Pro Lys Gln Asp Asp Gln Val Glu Pro Thr Phe Tyr Glu Thr Ser Glu

370 375 380Leu Ala Tyr Ser Ser Thr Arg Lys Ser Glu Ile Thr Arg Asn Glu Leu385 390 395 400Asn Leu Asn Glu Lys Phe Met Glu Phe Val Glu Val Tyr Glu Gly His

405 410 415Tyr Leu Asn Asp Ile Ile Lys Glu Ser Ser Glu Tyr Lys Glu Trp Val

420 425 430Lys Asn His Val Arg Phe Lys Glu Gly Val Cys Met Ala Leu Glu Ile

435 440 445Glu Glu Gln Pro Arg Ala Lys Ser Thr Pro Leu Ser Ile Glu Asn Ser

450455460 Arg Val Val Cys Val Lys Lys GlyAsn Tyr Leu Phe Asn Glu Val 465470475 (2) SEQ ID NO 1048 information

Sequence properties:

(A) length: 269 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...269

(xi) sequence representation: SEQ ID NO 1048: Val Lys Val Tyr Pro Gln Val Leu Ser Ile Ala Gly Ser Asp Ser Gly 151015 Gly Gly Ala Gly Ile Gln Ala Asp Leu Lys Ala Phe Gln Thr Phe Gly

20 25 30Val Phe Gly Thr Ser Val Ile Thr Cys Ile Thr Ala Gln Asn Thr Gln

35 40 45Gly Val His Gly Val Tyr Pro Leu Ser Val Glu Ser Val Lys Ala Gln

50 55 60Ile Leu Ala Ile Arg Asp Asp Phe Ser Ile Lys Ala Phe Lys Met Gly65 70 75 80Ala Leu Cys Asn Ala Gln Ile Ile Glu Cys Val Ala Asn Ala Leu Glu

85 90 95Thr Cys Asp Phe Gly Leu Cys Val Leu Asp Pro Val Met Val Ala Lys

100 105 110Asn Gly Ala Leu Leu Leu Glu Glu Glu Ala Ile Leu Ser Leu Lys Lys

115 120 125Ar9 Leu Leu Pro Lys Thr Asn Leu Leu Thr Pro Asn Leu Pro Glu Val

130 135 140Tyr Ala Leu Thr Gly Val Gln Ala Arg Asp Asp Lys Ser Ala Ser Lys145 150 155 160Ala Met Gly Val Leu Arg Asp Leu Gly Val Lys Asn Ala Val Ile Lys

165 170 175Gly Gly His Thr Glu His Phe Gln Gly Glu Phe Ser Asn Asp Trp Val

180 185 190Phe Leu Glu Asp Ala Glu Phe Ile Leu Ser Ala Lys Arg Phe Asn Thr

195 200 205Lys Asn Thr His Gly Thr Gly Cys Thr Leu Ser Ser Leu Ile Val Gly

210 215 220Leu Leu Ala Gln Gly Leu Asp Leu Lys Asn Ala Ile Thr Lys Ala Lys225 230 235 240Glu Leu Leu Thr Ile Ile Ile Gln Asn Pro Leu Asn Ile Gly His Gly

245 250 255His Gly Pro Leu Asn Leu Trp Ser Ile Lys Lys His Val

260265 (2) SEQ ID NO 1049 information

Sequence properties:

(A) length: 398 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...398

(xi) sequence representation: SEQ ID NO 1049: Leu Gly Ala Ile Met Asp Thr Phe Leu Thr Ser Ile LeuVal Leu Leu 151015 Met Arg Gly Leu Leu Asn Gln Arg Ala Ile Met Gln Gly Leu Met Trp

20 25 30Trp Ile Pro Leu Phe Tyr Asp Thr Ile Thr Lys Asp Val Phe Gly Phe

35 40 45Lys Ala Gly Arg Tyr Glu Ala Asn Ile Asp Phe Met Ser Gly Ser Asn

50 55 60Gln Gly Trp Glu Val Tyr Tyr Gln Pro Tyr Lys Thr Glu Thr Gln Arg65 70 75 80Leu Arg Phe Trp Trp Trp Ser Ser Phe Gly Arg Gly Leu Ala Phe Asn

85 90 95Ser Trp Ile Tyr Glu Phe Phe Ala Thr Val Pro Tyr Leu Lys Lys Gly

100 105 110Gly Asn Pro Ser Asn Ser Asn Asp Phe Ile Asn Tyr Gly Trp His Gly

115 120 125Ile Thr Thr Thr Tyr Ser Tyr Lys Gly Leu Asp Ala Gln Phe Phe Tyr

130 135 140Tyr Phe Ala Pro Lys Thr Tyr Asn Ala Pro Gly Phe Lys Leu Val Tyr145 150 155 160Asp Thr Asn Arg Asn Phe Glu Asn Val Gly Phe Arg Ser Gln Ser Met

165 170 175Ile Met Thr Thr Phe Pro Leu Tyr Tyr Arg Gly Trp Tyr Asn Pro Glu

180 185 190Thr Asn Thr Tyr Ser Leu Glu Asp Ser Thr Pro His Gly Ser Leu Leu

195 200 205Gly Arg Asn Gly Val Thr Leu Ash Ile Arg Gln Val Phe Trp Trp Asp

210 215 220Asn Phe Asn Trp Ser Ile Gly Phe Tyr Asn Thr Phe Gly Asn Ser Asp225 230 235240Ala Phe Leu Gly Ser His Thr Met Pro Arg Gly Asn Asn Thr Ser Tyr

245 250 255Ile Ser Asn Glu Ile Ser Val Thr Thr Arg His Ala Gly Met Ile Gly

260 265 270Tyr Asp Phe Trp Asp Asn Thr Ala Tyr Asp Gly Leu Ala Asp Ala Ile

275 280 285Thr Asn Ala Asn Thr Phe Thr Phe Tyr Thr Ser Val Gly Gly Ile His

290 295 300Lys Arg Phe Ala Trp His Val Phe Gly Arg Val Ser His Ala Asn Lys305 310 315 320Asn Ala Leu Gly Gln Val Gly Arg Ala Asn Glu Tyr Ser Leu Gln Phe

325 330 335Asn Ala Ser Tyr Ala Phe Thr Glu Ser Val Leu Leu Asn Phe Arg Ile

340 345 350Thr Tyr Tyr Gly Ala Arg Ile Asn Lys Gly Tyr Gln Ala Gly Tyr Phe

355 360 365Gly Ala Pro Lys Phe Asn Asn Pro Asp Gly Asp Phe Ser Ala Asn Tyr

370375380 Gln Asp Arg Ser Tyr Met Met Thr Asn Leu Thr Leu Lys Phe 385390395 (2) SEQ ID NO:1050 information

Sequence properties:

(A) length: 444 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...444

(xi) sequence representation: 1050: Leu Ser Asn Ala Phe Ser Gln Tyr Leu Tyr Ser Leu Leu Gly Ala Tyr 151015 Pro Thr Lys Leu Asn Gly Asn Asp Val Ser Ala Asn Ala Leu Leu Ser SEQ ID NO

20 25 30Gly Ala Val Gly Ser Gly Thr Cys Ala Ala Ala Gly Thr Ala Gly Gly

35 40 45Thr Thr Leu Asn Thr Gln Ser Ala Cys Thr Ala Ala Gly Tyr Tyr Trp

50 55 60Leu Pro Ser Leu Thr Asp Arg Ile Leu Ser Thr Ile Gly Ser Gln Thr65 70 75 80Asn Tyr Gly Thr Asn Thr Asn Phe Pro Asn Met Gln Gln Gln Leu Thr

85 90 95Tyr Leu Asn Ala Gly Asn Val Phe Phe Asn Ala Met Asn Lys Ala Leu

100 105 110Glu Lys Asn Gly Thr Ala Thr Ala Asn Ser Thr Ser Ser Thr Ser Gly

115 120 125Ala Thr Gly Ser Asp Gly Gln Thr Tyr Ser Gln Gln Ala Ile Gln Tyr

130 135 140Leu Gln Gly Gln Gln Asn Ile Leu Asn Asn Ala Ala Asn Leu Leu Lys145 150 155 160Gln Asp Glu Leu Leu Leu Glu Ala Phe Asn Ser Ala Val Ala Ala Asn

165 170 175Ile Gly Asn Lys Glu Phe Asn Ser Ala Ala Phe Thr Gly Leu Val Gln

180 185 190Gly Ile Ile Asp Gln Ser Gln Leu Val Tyr Asn Glu Leu Thr Lys Asn

195 200 205Thr Ile Ser Gly Ser Ala Val Asn Asn Ala Gly Ile Asn Ser Asn Gln

210 215 220Ala Asn Ala Val Gln Gly Arg Ala Ser Gln Leu Pro Asn Ala Leu Tyr225 230 235 240Asn Val Gln Val Thr Leu Asp Lys Ile Asn Ala Leu Asn Asn Gln Val

245 250 255Arg Ser Met Pro Tyr Leu Pro Gln Phe Arg Ala Gly Asn Ser Arg Ala

260 265 270Thr Asn Ile Leu Asn Gly Phe Tyr Thr Lys Val Gly Tyr Lys Gln Phe

275 280 285Phe Gly Lys Lys Arg Asn Ile Gly Leu Arg Tyr Tyr Gly Phe Phe Ser

290 295 300Tyr Asn Gly Ala Ser Val Gly Phe Arg Ser Thr Gln Asn Asn Val Gly305 310 315 320Leu Tyr Thr Tyr Gly Val Gly Thr Asp Val Leu Tyr Asn Ile Phe Ser

325 330 335Arg Ser Tyr Gln Asn Arg Ser Val Asp Met Gly Phe Phe Ser Gly Ile

340 345 350Gln Leu Ala Gly Glu Thr Phe Gln Ser Thr Leu Arg Asp Asp Pro Asn

355 360 365Val Lys Leu His Gly Lys Ile Asn Asn Thr His Phe Gln Phe Leu Phe

370 375 380Asp Phe Gly Met Arg Met Asn Phe Gly Lys Leu Asp Gly Lys Ser Asn385 390 395 400Arg His Asn Gln His Thr Val Glu Phe Gly Val Val Val Pro Thr Ile

405 410 415Tyr Asn Thr Tyr Tyr Lys Ser Ala Gly Thr Thr Val Lys Tyr Phe Arg

420 425 430Pro Tyr Ser Val Tyr Trp Ser Tyr Gly Tyr Ser Phe

435440 (2) SEQ ID NO 1051 message

Sequence properties:

(A) length: 133 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...133

(xi) sequence representation: SEQ ID NO:1051: Met Glu Leu Ile Lys Lys Leu Glu Lys Glu Ser Glu Val Leu Lys Lys 151015 Asp Leu Gln Gln His Ser Asn Glu Leu Phe Lys Met Leu Ile Ile Asp

20 25 30Asn Glu Asp Leu Phe Lys Glu Gln Phe Glu Ile Met Phe Lys Ala Trp

35 40 45Val Glu Ile Val Lys Met Met Phe Glu Leu Thr Lys Lys Thr Lys Phe

50 55 60Asp Gly Glu Met Ile Gly Tyr Thr Glu Glu Leu Leu Thr Phe Leu Val65 70 75 80Arg Asp Phe Phe Asn Gly Ile Phe Lys Ser Lys Val Ile Pro Lys Met

85 90 95Pro Ile Phe Cys Gly Asp Val Lys Cys Glu Asp Phe Asn Ala Leu Arg

100 105 110Ser Leu Val Tyr Leu Ser Val Leu Glu Leu Glu Glu Thr Ile Ash Pro

115 120 125Asn Lys Ile Pro Phe

130(2) SEQ ID NO 1052 information

Sequence properties:

(A) length: 696 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...696

(xi) sequence representation: 1052: Met Lys Ile Lys Lys Ser Leu Phe Ala Leu Ser Phe Ser Leu Met Ala 151015 Ser Leu Ser Arg Ala Glu Asp Asp Gly Phe Tyr Met Ser Val Gly Tyr SEQ ID NO

20 25 30Gln Ile Gly Glu Ala Val Gln Lys Val Lys Asn Thr Gly Ala Leu Gln

35 40 45Asn Leu Ala Asp Arg Tyr Asp Asn Leu Ser Asn Leu Leu Asn Gln Tyr

50 55 60Asn Tyr Leu Asn Ser Leu Val Asn Leu Ala Ser Thr Pro Ser Ala Ile65 70 75 80Thr Gly Ala Ile Asp Asn Leu Ser Ser Ser Ala Ile Asn Leu Thr Ser

85 90 95Ala Thr Thr Thr Ser Pro Ala Tyr Gln Ala Val Ala Leu Ala Leu Asn

100 105 110Ala Ala Val Gly Met Trp Gln Val Ile Ala Phe Gly Ile Ser Cys Gly

115 120 125Pro Gly Pro Ash Leu Gly Pro Glu His Leu Glu Asn Gly Gly Val Arg

130 135140Ser Phe Asp Asn Thr Pro Asn Tyr Ser Tyr Asn Thr Gly Ser Gly Thr145 150 l55 160Thr Thr Thr Thr Cys Asn Gly Ala Ser Asn Val Gly Pro Asn Gly Ile

165 170 175Leu Ser Ser Ser Glu Tyr Gln Val Leu Asn Thr Ala Tyr Gln Thr Ile

180 185 190Gln Thr Ala Leu Ash Gln Asn Gln Gly Gly Gly Met Pro Ala Leu Asn

195 200 205Ser Ser Lys Asn Met Val Val Asn Ile Asn Gln Thr Phe Thr Lys Asn

210 215 220Pro Thr Thr Glu Tyr Thr Tyr Pro Asp Gly Asn Gly Asn Tyr Tyr Ser225 230 235 240Gly Gly Ser Ser Ile Pro Ile Gln Leu Lys Ile Ser Ser Val Asn Asp

245 250 255Ala Glu Asn Leu Leu Gln Gln Ala Ala Thr Ile Ile Asn Val Leu Thr

260 265 270Thr Gln Asn Pro His Val Asn Gly Gly Gly Gly Ala Trp Gly Phe Gly

275 280 285Gly Lys Thr Gly Asn Val Met Asp Ile Phe Gly Asp Ser Phe Asn Ala

290 295 300Ile Asn Glu Met Ile Lys Asn Ala Gln Ala Val Leu Glu Lys Thr Gln305 310 315 320Gln Leu Asn Ala Asn Glu Asn Thr Gln Ile Thr Gln Pro Asp Asn Phe

325 330 335Asn Pro Tyr Thr Ser Lys Asp Thr Gln Phe Ala Gln Glu Met Leu Asn

340 345 350Arg Ala Asn Ala Gln Ala Glu Ile Leu Ser Leu Ala Gln Gln Val Ala

355360 365Asp Asn Phe His Ser Ile Gln Gly Pro Ile Gln Gln Asp Leu Glu Glu

370 375 380Cys Thr Ala Gly Ser Ala Gly Val Ile Asn Asp Asn Thr Tyr Gly Ser385 390 395 400Gly Cys Ala Phe Val Lys Glu TPr Leu Asn Ser Leu Glu Gln His Thr

405 410 415Ala Tyr Tyr Gly Asn Gln Val Asn Gln Asp Arg Ala Leu Ser Gln Thr

420 425 430Ile Leu Asn Phe Lys Glu Ala Leu Ser Thr Leu Gly Asn Asp Ser Lys

435 440 445Ala Ile Asn Ser Gly Ile Ser Asn Leu Pro Asn Ala Lys Ser Leu Gln

450 455 460Asn Met Thr His Ala Thr Gln Asn Pro Asn Ser Pro Glu Gly Leu Leu465 470 475 480Thr Tyr Ser Leu Asp Thr Ser Lys Tyr Asn Gln Leu Gln Thr Val Ala

485 490 495Gln Glu Leu Gly Lys Asn Pro Phe Arg Arg Ile Gly Val Ile Asn Tyr

500 505 510Gln Asn Asn Asn Gly Ala Met Asn Gly Ile Gly Val Gln Ala Gly Tyr

515 520 525Lys Gln Phe Phe Gly Lys Lys Arg Asn Trp Gly Leu Arg Tyr Tyr Gly

530 535 540Phe Phe Asp Tyr Asn His Ala Tyr Ile Lys Ser Asn Phe Phe Asn Ser545 550 555 560Ala Ser Asp Val Trp Thr Tyr Gly Val Gly Met Asp Ala Leu Tyr Asn

565 570 575Phe Ile Asn Asp Lys Asn Thr Asn Phe Leu Gly Lys Asn Asn Lys Leu

580 585590Ser Val Gly Leu Phe Gly Gly Phe Ala Leu Ala Gly Thr Ser Trp Leu

595 600 605Asn Ser Gln Gln Val Asn Leu Thr Met Met Asn Gly Ile Tyr Asn Ala

610 615 620Asn Val Ser Ala Ser Asn Phe Gln Phe Leu Phe Asp Leu Gly Leu Arg625 630 635 640Met Asn Leu Ala Arg Pro Lys Lys Lys Asp Ser Asp His Ala Ala Gln

645 650 655His Gly Met Glu Leu Gly Val Lys Ile Pro Thr Ile Asn Thr Asp Tyr

660 665 670Tyr Ser Phe Met Gly Ala Glu Leu Lys Tyr Arg Arg Leu Tyr Ser Val

675 680 685Tyr Leu Asn Tyr Val Phe Ala Tyr

690695 (2) SEQ ID NO:1053 information

Sequence properties:

(A) length: 371 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...371

(xi) sequence representation: SEQ ID NO 1053: Met Gln Phe Gln Lys Thr Leu Ser Ser Leu Ser Leu Phe Leu Ser Leu 151015 Ser Leu Phe Leu Ser Phe Ser Ile Ala Glu Glu Asn Gly Ala Tyr Ala

20 25 30Ser ValGly Phe Glu Tyr Ser Ile Ser His Ala Val Glu His Asn Asn

35 40 45Pro Phe Leu Asn Gln Glu Arg Ile Gln Thr Ile Ser Asn Ala Gln Asn

50 55 60Lys Ile Tyr Lys Leu Asn Gln Val Lys Asn Glu Ile Thr Asn Met Pro65 70 75 80Asn Thr Phe Asn Tyr Ile Asn Asn Ala Leu Lys Asn Asn Ala Lys Leu

85 90 95Thr Pro Thr Glu Lys Gln Ala Glu Thr Tyr Tyr Leu Gln Ser Thr Leu

100 105 110Gln Asn Ile Glu Lys Ile Val Met Leu Ser Gly Gly Val Ala Ser Asn

115 120 125Pro Lys Leu Ala Gln Ala Leu Glu Lys Met Gln Glu Pro Ile Thr Asn

130 135 140Pro Leu Glu Leu Val Glu Asn Leu Lys Asn Leu Glu Leu Gln Phe Ser145 150 155 160Gln Ser Gln Asn Ser Met Leu Ser Ser Leu Ser Ser Gln Ile Ala Gln

165 170 175Ile Ser Asn Ser Leu Asn Ala Leu Asp Pro Ser Ser Tyr Ser Lys Asn

180 185 190Val Ser Ser Met Tyr Gly Val Gly Leu Ser Val Gly Tyr Lys His Phe

195 200 205Phe Thr Lys Lys Lys Asn Gln Gly Phe Arg Tyr Tyr Leu Phe Tyr Asp

210 215 220Tyr Gly Tyr Thr Asn Phe Gly Phe Val Gly Asn Gly Phe Asp Gly Leu225 230 235 240Gly Lys Met Asn Asn His Leu Tyr Gly Leu Gly Ile Asp Tyr Leu Phe

245 250 255Asn PheIle Asp Asn Ala Gln Lys His Ser Ser Val Gly Phe Tyr Val

260 265 270Gly Phe Ala Leu Ala Gly Ser Ser Trp Val Gly Ser Gly Leu Gly Met

275 280 285Trp Val Ser Gln Met Asp Phe Ile Asn Asn Tyr Leu Thr Asp Tyr Arg

290 295 300Ala Lys Met His Thr Ser Phe Phe Gln Ile Pro Leu Asn Phe Gly Val305 310 315 320Arg Val Asn Val Asp Arg His Asn Gly Phe Glu Met Gly Leu Lys Ile

325 330 335Pro Leu Ala Val Asn Ser Phe Tyr Glu Thr His Gly Lys Gly Leu Asn

340 345 350Ala Ser Leu Phe Phe Lys Arg Leu Val Met Phe Asn Val Ser Tyr Val

355 360 365Tyr Ser Phe

370(2) SEQ ID NO 1054 message

Sequence properties:

(A) length: 484 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...484

(xi) sequence representation: SEQ ID NO 1054: Met Ala Lys Ile Thr Thr Val Ile Asp Ile Gly Ser Asn Ser Val Arg 151015 Leu Ala Val Phe Lys Lys Thr Ser Gln Phe Gly Phe Tyr Leu Leu Phe

20 25 30Glu Thr Lys Ser Lys Val Arg Ile Ser Glu Gly Cys Tyr Ala Phe Lys

35 40 45Gly Val Leu Gln Glu Ile Pro Met Gln Arg Ala Val Lys Ala Leu Ser

50 55 60Glu Phe Lys Glu Ile Ala Leu Lys Tyr Lys Ser Lys Lys Ile Leu Cys65 70 75 80Val Ala Thr Ser Ala Val Arg Asp Ala Pro Asn Arg Leu Glu Phe Val

85 90 95Ala Arg Val Lys Lys Ala Cys Gly Leu Gln Ile Lys Ile Ile Asp Gly

100 105 110Gln Lys Glu Ala Leu Tyr Gly Gly Ile Ala Cys Ala Asn Leu Leu His

l15 120 125Lys Asn Ser Gly Ile Thr Ile Asp Ile Gly Gly Gly Ser Thr Glu Cys 130 135 140Ala Leu Ile Glu Lys Gly Lys Ile Lys Asp Leu Ile Ser Leu Asp Val145 150 155 160Gly Thr Ile Arg Ile Lys Glu Met Phe Leu Asp Lys Asp Leu Asp Val

165 170 175Lys Leu Ala Lys Ala Phe Ile Gln Lys Glu Val Ser Lys Leu Pro Phe

180 185 190Lys His Lys Asn Ala Phe Gly Val Gly Gly Thr Ile Arg Ala Leu Ser

195 200 205Lys Val Leu Met Lys Arg Phe Asp Tyr Pro Ile Asp Ser Leu His Gly

210 215 220Tyr Glu Ile Asp Ala His Lys Asn Leu Ala Phe Ile Glu Lys Ile Val225 230 235 240Met Leu Lys Glu Asp Lys Leu Arg Leu Leu Gly Val Asn Glu Glu Arg

245250 255Leu Asp Ser Ile Arg Ser Gly Ala Leu Ile Leu Ser Val Val Leu Glu

260 265 270His Leu Lys Thr Ser Leu Met Ile Thr Ser Gly Val Gly Val Arg Glu

275 280 285Gly Val Phe Leu Ser Asp Leu Leu Arg His His Tyr His Lys Phe Pro

290 295 300Pro Asn Ile Asn Pro Ser Leu Ile Ser Leu Lys Asp Arg Phe Leu Pro305 310 315 320His Glu Lys His Ser Gln Lys Val Lys Lys Glu Cys Val Lys Leu Phe

325 330 335Glu Val Leu Ser Pro Leu His Lys Ile Asp Glu Lys Tyr Leu Phe His

340 345 350Leu Lys Ile Ala Gly Glu Leu Ala Ser Met Gly Lys Ile Leu Ser Val

355 360 365Tyr Leu Ala His Lys His Ser Ala Tyr Phe Ile Leu Asn Ala Leu Ser

370 375 380Tyr Gly Phe Ser His Gln Asp Arg Ala Ile Ile Cys Leu Leu Ala Gln385 390 395 400Phe Ser His Lys Lys Ile Pro Lys Asp Asn Ala Ile Ala His Met Ser

405 410 415Ala Met Met Pro Ser Leu Leu Thr Leu Gln Trp Leu Ser Phe Ile Leu

420 425 430Ser Leu Ala Glu Asn Leu Cys Leu Thr Asp Ser His His Leu Lys Tyr

435 440 445Thr Leu Glu Lys Asn Lys Leu Val Ile His Ser Asn Asp Ala Leu Tyr

450455460 Leu Ala Lys Glu Met Leu Pro Lys Leu Ile Lys Pro Ile Pro Leu Thr 465470475480 Ile Glu Phe Ala (2) SEQ ID NO:1055 information

Sequence properties:

(A) length: 253 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...253

(xi) sequence representation: SEQ ID NO 1055: Lys Gln Val Lys Ser Arg Met Lys Glu Lys Pro Phe Asn Ser Glu Gln 151015 Met Ala Phe Leu Glu Glu Leu Leu Ser His Gln Glu Lys His Leu Glu

20 25 30Ser Lys Leu Ser Gly Phe Ser Val Asn Asp Leu Asp Met Gln Ser Val

35 40 45Phe Arg Leu Glu Arg Asn Arg Leu Lys Ile Ala Tyr Arg Leu Leu Gly

50 55 60Leu Met Ser Phe Ile Ala Leu Val Leu Ala Ile Val Leu Ile Ser Ile65 70 75 80Leu Pro Leu Gln Lys Thr Glu His His Phe Val Asp Phe Leu Asn Gln

85 90 95Asp Lys His Tyr Ala Ile Ile Gln Arg Ala Asp Lys Ser Ile Ser Ser

100 105 110Asn Glu Ala Leu Ala Arg Ser Leu Ile Gly Ala Tyr Val Leu Asn Arg

115 120 125Glu Ser Ile Asn Arg Ile Asp Asp Lys Ser Arg Tyr Glu Leu Val Arg

130 135 140Leu Gln Ser Ser Ser Lys Val Trp Gln Arg Phe Glu Asp Leu Ile Lys145 150 155 160Ala Gln Asn Ser Ile Tyr Val Gln Ser His Leu Glu Arg Glu Val His

165 170 175Ile Val Asn Ile Ala Ile Tyr Gln Gln Aap Ash Asn Pro Ile Ala Ser

180 185 190Val Ser Ile Ala Ala Lys Leu Leu Asn Glu Asn Lys Leu Val Tyr Glu

195 200 205Lys Arg Tyr Lys Ile Val Leu Ser Tyr Leu Phe Asp Thr Pro Asp Phe

210 215 220Asp Tyr Ala Ser Met Pro Lys Asn Pro Thr Gly Phe Lys Ile Thr Arg225 230 235 240Tyr Ser Ile Thr Glu Ile Ala Pro Thr Asn Arg Asn Asp

245620 (2) SEQ ID NO 1056 information

(i) Sequence Properties:

(A) length: 479 an amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...479

(xi) sequence representation: SEQ ID NO 1056: Met Lys Lys Ser Leu Cys Leu Ser Phe Phe Leu Thr Phe Ser Asn Pro 151015 Leu Gln Ala Leu Val Ile Glu Leu Leu Glu Glu Ile Lys Thr Ser Pro

20 25 30His Lys Gly Thr Phe Lys Ala Lys Val LeuAsp Ser Lys Glu Pro Arg

35 40 45Gln Val Leu Gly Val Tyr Asn Ile Ser Pro His Lys Lys Leu Thr Leu

50 55 60Thr Ile Thr His Ile Ser Thr Ala Ile Val Tyr Gln Pro Leu Asp Glu65 70 75 80Lys Leu Ser Leu Glu Thr Thr Leu Ser Pro Asn Arg Pro Thr Ile Pro

85 90 95Arg Asn Thr Gln Ile Val Phe Ser Ser Lys Glu Leu Lys Glu Pro His

100 105 110Ser Asn Pro Ile Pro Ser Leu Asn Ala Pro Met Gln Lys Pro Gln Asn

115 120 125Lys Pro Ser Ser Ser Gln Gln Ser Pro Gln Asn Phe Ser Tyr Pro Glu

130 135 140Ser Lys Leu Gly Ser Lys Asn Ser Lys Asn Ser Leu Leu Gln Pro Leu145 150 155 160Val Thr Pro Ser Lys Val Ser Pro Thr Asn Glu Val Lys Thr Pro Thr

165 170 175Asn Asp Ala Asn Pro Pro Leu Lye His Ser Ser Gln Asp Gln Glu Asn

180 185 190Asn Leu Phe Val Ala Pro Pro Thr Glu Lys Thr Leu Pro Asn Asn Thr

195 200 205Ser Ser Ala Asp Ala Ser Glu Asn Asn Glu Ser Asn Glu Asn Arg Asp

210 215 220Asn Val Glu Lys Gln Ala Ile Arg Asp Pro Asn Ile Lys Glu Phe Ala225 230 235 240Cys Gly Lys Trp Val Tyr Asp Asp Glu Asn Leu Gln Ala Tyr Arg Pro

245 250 255Ser Ile Leu Lys Arg Val Asp Lys Asp Lys Glu Ile Thr Thr Asp Ile

260 265 270Thr Pro Cys Asp Tyr Ser Thr Ala Glu Asn Lys Ser Gly Lys Ile Ile

275 280 285Thr Pro Tyr Thr Lys Ile Ser Val His Lys Thr Glu Pro Leu Glu Asp

290 295 300Pro Gln Thr Phe Glu Ala Lys Asn Asn Phe Ala Ile Leu Gln Ala Arg305 310 315 320Ser Ser Thr Glu Lys Cys Lys Arg Ala Arg Ala Arg Lys Asp Gly Thr

325 330 335Thr Arg Gln Cys Tyr Leu Ile Glu Glu Pro Leu Lys Gln Ala Trp Glu

340 345 350Ser Glu Tyr Glu Ile Thr Thr Gln Leu Val Lys Ala Ile Tyr Glu Arg

355 360 365Pro Lys Gln Asp Asp Gln Val Glu Pro Thr Phe Tyr Glu Thr Ser Glu

370 375 380Leu Ala Tyr Ser Ser Thr Arg Lys Ser Glu Ile Thr Arg Asn Gru Leu385 390 395 400Asn Leu Asn Glu Lys Phe Met Glu Phe Val Glu Val Tyr Glu Gly His

405 410 415Tyr Leu Asn Asp Ile Ile Lys Glu Ser Ser Glu Tyr Lys Glu Trp Val

420 425 430Lys Asn His Val Arg Phe Lys Glu Gly Val Cys Met Ala Leu Glu Ile

435 440 445Glu Glu Gln Pro Arg Ala Lys Ser Thr Pro Leu Ser Ile Glu Asn Ser

450455460 Arg Val Val Cys Val Lys Lys Gly Asn Tyr Leu Phe Asn Glu Val 465470475 (2) SEQ ID NO:1057 information

Sequence properties:

(A) length: 567 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...567

(xi) sequence representation: SEQ ID NO 1057: Met Ile Phe Gly Asp Phe Lys Tyr Gln Lys Ser Val Lys Lys Leu Thr 151015 Ala Thr Asn Leu Asn Glu Leu Lys Asn Ala Leu Asp Phe Ile Ser Gln

20 25 30Asn Arg Gly Lys Gly Tyr Phe Val Gly Tyr Leu Leu Tyr Glu Ala Arg

35 40 45Leu Ala Phe Leu Asp Glu Asn Phe Gln Ser Gln Thr Pro Phe Leu Tyr

50 55 60Phe Glu Gln Phe Leu Glu Arg Lys Lys Tyr Pro Leu Glu Pro Leu Lys65 70 75 80Glu His Ala Phe Tyr Pro Lys Ile His Ser Ser Leu Asp Gln Lys Thr

85 90 95Tyr Phe Lys Gln Phe Lys Ala Val Lys Glu His Leu Lys Asn Gly Asp

100 105 110Thr Tyr Gln Val Asn Leu Thr Met Asp Leu Leu Leu Asn Thr Lys Ala

115 120 125Lys Pro Lys Arg Val Phe Lys Glu Val Ile His Asn Gln Asn Thr Pro 130 135 140Phe Lys Ala Phe Ile Glu Asn Glu Phe Gly Ser Val Leu Ser Phe Ser145 150 155 160Pro Glu Leu Phe Phe Glu Leu Glu PheLeu Asp Thr Ala Ile Lys Ile

165 170 175Ile Thr Lys Pro Met Lys Gly Thr Ile Ala Arg Ser Asn Asn Pro Leu

180 185 190Ile Asp Glu Lys Asn Arg Leu Phe Leu Gln Asn Asp Asp Lys Asn Arg

195 200 205Ser Glu Asn Val Met Ile Val Asp Leu Leu Arg Asn Asp Leu Ser Arg

210 215 220Leu Ala Leu Lys Asn Ser Val Lys Val Asn Gln Leu Phe Glu Ile Ile225 230 235 240Ser Leu Pro Ser Val Tyr Gln Met Ile Ser Glu Ile Glu Ala Gln Leu

245 250 255Pro Leu Lys Thr Ser Leu Phe Glu Ile Phe Lys Ala Leu Phe Pro Cys

260 265 270Gly Ser Val Thr Gly Cys Pro Lys Ile Lys Thr Met Gln Ile Ile Glu

275 280 285Ser Leu Glu Lys Arg Pro Arg Gly Val Tyr Cys Gly Ala Ile Gly Met

290 295 300Val Gly Gly Lys Lys Ala Leu Phe Ser Val Pro Ile Arg Thr Leu Glu305 310 315 320Lys Arg Ala His Glu Asp Phe Leu His Leu Gly Val Gly Ser Gly Val

325 330 335Thr Tyr Lys Ser Lys Ala Ser Lys Glu Tyr Glu Glu Ser Phe Leu Lys

340 345 350Ser Phe Phe Val Met Pro Lys Ile Glu Phe Glu Ile Val Glu Thr Met

355 360 365Arg Val Ile Lys Arg Asp Gln Lys Leu Glu Ile Asn Asn Lys Asn Ala

370 375 380His Lys Glu Arg Leu Met His Ser AlaGln Tyr Phe Asn Phe Lys Tyr385 390 395 400Asp Glu Asn Leu Leu Asp Phe Glu Leu Glu Lys Glu Gly Val Leu Arg

405 410 415Val Leu Leu Asn Lys Arg Gly Lys Leu Ile Lys Glu Tyr Arg Thr Leu

420 425 430Glu Pro Leu Lys Ser Leu Glu Ile Arg Leu Ser Glu Ala Pro Ile Asp

435 440 445Lys His Asp Asp Phe Leu Tyr His Lys Thr Ala Tyr Ala Pro Phe Tyr

450 455 460Gln Asn Ala Arg Ala Leu Ile Lys Lys Gly Val Ile Phe Asp Glu Ile465 470 475 480Phe Tyr Asn Gln Asp Leu Glu Leu Thr Glu Gly Ala Arg Ser Asn Leu

485 490 495Ile Leu Glu Ile His Asn Arg Leu Leu Thr Pro Tyr Phe Ser Val Gly

500 505 510Ala Leu Thr Gly Thr Gly Val Val Gly Leu Leu Lys Lys Gly Leu Val

515 520 525Glu His Ala Pro Leu Lys Leu Gln Asp Leu Gln Arg Ala Ala Lys Ile

530 535 540Tyr Cys Ile Asn Ala Leu Tyr Gly Leu Val Glu Val Gly Ile Ile Gly545 550 555 560Tyr Pro Met Glu Gln Lys Ser

565(2) SEQ ID NO:1058 message

Sequence properties:

(A) length: 374 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...374

(xi) sequence representation: SEQ ID NO:1058: Met Lys Ile Ser Val Ser Lys Asn Asp Leu Glu Asn Thr Leu Arg Tyr 151015: 151015 Leu Gln Ala Phe Leu Asp Lys Lys Asp Ala Ser Ser Ile Ala Ser His

20 25 30Ile His Leu Glu Val Ile Lys Glu Lys Leu Phe Leu Lys Ala Ser Asp

35 40 45Ser Asp Ile Gly Leu Lys Ser Tyr Ile Ser Thr Gln Ser Thr Asp Lys

50 55 60Glu Gly Val Gly Thr Ile Asn Gly Lys Lys Phe Leu Asp Ile Ile Ser65 70 75 80Cys Leu Lys Asp Ser Asn Ile Val Leu Glu Thr Lys Asp Asp Ser Leu

85 90 95Val Ile Lys Gln Asn Lys Ser Ser Phe Lys Leu Pro Met Phe Asp Ala

100 105 110Asp Glu Phe Pro Glu Phe Pro Val Ile Asp Pro Lys Val Ser Leu Glu

115 120 125Ile Asn Ala Pro Phe Leu Val Asp Ala Phe Lys Lys Ile Ala Pro Val

130 135 140Ile Glu Gln Thr Ser His Lys Arg Glu Leu Ala Gly Val Leu Met Gln145 150 155 160Phe Asn Gln Lys His Gln Thr Leu Ser Val Val Gly Thr Asp Thr Lys

165 170 175Arg Leu Ser Tyr Thr Gln Leu Glu Lys Ile Ser Ile His Ser Thr Glu

180185 190Glu Asp Ile Ser Cys Ile Leu Pro Lys Arg Ala Leu Leu Glu Ile Leu

195 200 205Lys Leu Phe Tyr Glu Asn Phe Ser Phe Lys Ser Asp Gly Met Leu Ala

210 215 220Val Val Glu Asn Glu Thr His Ala Phe Phe Thr Lys Leu Ile Asp Gly225 230 235 240Asn Tyr Pro Asp Tyr Gln Lys Ile Leu Pro Lys Glu Tyr Thr Ser Ser

245 250 255Phe Thr Leu Gly Lys Glu Glu Phe Lys Glu Gly Ile Lys Leu Cys Ser

260 265 270Ser Leu Ser Ser Thr Ile Lys Leu Thr Leu Glu Lys Asn Asn Ala Leu

275 280 285Phe Glu Ser Leu Asp Ser Glu His Ser Glu Thr Ala Lys Thr Ser Val

290 295 300Glu Ile Glu Lys Gly Leu Asp Ile Glu Lys Ala Phe His Leu Gly Val305 310 315 320Asn Ala Lys Phe Phe Leu Glu Ala Leu Asn Ala Leu Gly Thr Thr Gln

325 330 335Phe Val Leu Lys Cys Asn Glu Pro Ser Ser Pro Phe Leu Ile Gln Glu

340 345 350Pro Leu Asp Glu Lys Gln Ser His Leu Asn Ala Lys Ile Ser Thr Leu

355360365 Met Met Pro Ile Thr Leu 370(2) SEQ ID NO 1059 information

Sequence properties:

(A) length: 368 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...368

(xi) sequence representation: SEQ ID NO 1059: Met Val Val Leu Gly Ser Thr Gly Ser Ile Gly Lys Asn Ala Leu Lys 151015 Ile Ala Lys Lys Phe Gly Val Lys Ile Glu Ala Leu Ser Cys Gly Lys

20 25 30Asn Ile Ala Leu Ile Asn Glu Gln Ile Lys Val Phe Lys Pro Lys Lys

35 40 45Val Ala Ile Leu Asp Pro Asn Asp Leu Asn Asn Leu Glu Pro Leu Gly

50 55 60Ala Glu Val Phe Val Gly Leu Asp Gly Ile Asp Ala Met Ile Glu Glu65 70 75 80Cys Val Ser Asn Leu Val Ile Asn Ala Ile Val Gly Val Ala Gly Leu

85 90 95Lys Ala Ser Phe Lys Ser Leu Gln Arg Asn Lys Lys Leu Ala Leu Ala

100 105 110Asn Lys Glu Ser Leu Val Ser Ala Gly His Leu Leu Asp Ile Ser Gln

115 120 125Ile Thr Pro Val Asp Ser Glu Hls Phe Gly Leu Trp Ala Leu Leu Gln

130 135 140Asn Lys Thr Leu Lys Pro Lys Ser Leu Ile Ile Ser Ala Ser Gly Gly145 150 155 160Ala Phe Arg Asp Thr Pro Leu Asp Leu Ile Ala Ile Gln Asn Ala Gln

165 170 175Asn Ala Leu Lys His Pro Asn Trp Ser Met Gly Asp Lys Ile Thr Ile

180 185 190Asp Ser Ala Ser Met Val Asn Lys Leu Phe Glu Ile Leu Glu Thr Tyr

195 200 205Trp Leu Phe Gly Ala Ser Leu Lys Ile Asp Ala Leu Ile Glu Arg Ser

210 215 220Ser Ile Val His Ala Leu Val Glu Phe Glu Asp Asn Ser Val Ile Ala225 230 235 240His Leu Ala Ser Ala Asp Met Gln Leu Pro Ile Ser Tyr Ala Ile Asn

245 250 255Pro Lys Leu Ala Ser Leu Ser Ala Ser Ile Lys Pro Leu Asp Leu Tyr

260 265 270Ala Leu Ser Ala Ile Lys Phe Glu Pro Ile Ser Val Glu Arg Tyr Thr

275 280 285Leu Trp Arg Tyr Lys Asp Leu Leu Leu Glu Asn Pro Lys Leu Gly Val

290 295 300Val Leu Asn Ala Ser Asn Glu Val Ala Met Lys Lys Phe Leu Asn Gln305 310 315 320Glu Ile Ala Phe Gly Gly Phe Ile Gln Ile Ile Ser Gln Ala Leu Glu

325 330 335Leu Tyr Ala Lys Lys Ser Phe Lys Leu Ser Ser Leu Asp Glu Val Leu

340 345 350Ala Leu Asp Lys Glu Val Arg Glu Arg Phe Gly Ser Val Ala Arg Val

355360365 (2) SEQ ID NO:1060 information

Sequence properties:

(A) length: 417 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...417

(xi) sequence representation: 1060: Met Lys Tyr Leu Trp Leu Phe Leu Ile Tyr Ala Ile Gly Leu Phe Ala 151015 Thr Asp Lys Thr Leu Asp Ile Ile Lys Thr Ile Gln Lys Leu Pro Lys SEQ ID NO

20 25 30Ile Glu Val Arg Tyr Ser Ile Asp Asn Asp Ala Asn Tyr Ala Leu Lys

35 40 45Leu His Glu Val Leu Ala Asn Asp Leu Lys Thr Ser Gln His Phe Asp

50 55 60Val Ser Gln Asn Lys Glu Gln Gly Ala Ile Asn Tyr Ala Glu Leu Lys65 70 75 80Asp Lys Lys Val His Leu Val Ala Leu Val Ser Val Ala Val Glu Asn

85 90 95Gly Asn Lys Ile Ser Arg Leu Lys Leu Tyr Asp Val Asp Thr Gly Thr

100 105 110Leu Lys Lys Thr Phe Asp Tyr Pro Ile Val Ser Leu Asp Leu Tyr Pro

115 120 125Phe Ala Ala His Asn Met Ala Ile Val Val Asn Asp Tyr Leu Lys Ala

130 135 140Pro Ser Ile Ala Trp Met Lys Arg Leu Ile Val Phe Ser Lys Tyr Ile145 150 155 160Gly Pro Gly Ile Thr Asn Ile Ala Leu Ala Asp Tyr Thr Met Arg Tyr

165 170 175Gln Lys Glu Ile Ile Lys Asn Asn Arg Leu Asn Ile Phe Pro Lys Trp

180 185 190Ala Asn Ala Glu Gln Thr Glu Phe Tyr Tyr Thr Gln Tyr Gly Glu Lys

195 200 205Thr Pro Met Ile Leu Lys Tyr Asn Ile Gln Lys Ala Thr His Glu Asn

210 215 220Ile Ala Ser Ser Gln Gly Met Ala Val Val Ser Ser Val Ser Ser Asp225 230 235 240Gly Ser Lys Ile Leu Met Ser Leu Ala Pro Asp Gly Gln Pro Asp Val

245 250 255Tyr Leu Tyr Asp Thr His Lys Lys Thr Lys Thr Lys Ile Thr Arg Tyr

260 265 270Pro Gly Ile Asp Val Ser Gly Val Phe Leu Glu Asp Asp Lys Ser Met

275 280 285Ala Phe Val Ser Asp Arg Ser Gly Tyr Pro Asn Ile Tyr Met Lys Lys

290 295 300Leu Gly Leu Lys Glu Ser Ala Glu Gln Leu Leu Tyr Glu Gly Arg Ser305 310 315 320Asn Glu Ser Ile Asp Ala Tyr Lys Asp Ser Ile Val Tyr Val Ser Arg

325 330 335Glu Asn Leu Asn Glu Phe Gly Lys Thr Val Phe Asn Leu Asn Leu Ile

340 345 350Ala Leu Asn Ser Lys Tyr Ile Arg Arg Leu Thr Val Asn Gly Ser Asn

355 360 365Gln Met Pro Arg Phe Ser Met Asp Gly Arg Asn Ile Met Tyr Ile Lys

370 375 380Lys Thr Ser Gln Glu Tyr Ala Met Gly Leu Ile Leu Leu Asp Tyr Asn385 390 395 400Gln Ser Phe Leu Phe Pro Leu Lys Asn Val Lys Ile Gln Ala Phe Asp

405410415 Trp (2) SEQ ID NO 1061 information

Sequence properties:

(A) length: 219 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...219

(xi) sequence representation: SEQ ID NO 1061: Val Asn Lys Lys His Arg Leu Ala Phe Leu Gly Leu Ile Val Gly Val 151015 Leu Phe Phe Phe Ser Ala Cys Gln His Arg Leu His Met Gly Tyr Tyr

20 25 30Ser Glu Val Thr Gly Asp Tyr Leu Phe Asn Tyr Asn Ser Thr Ile Val

35 40 45Val Ala Tyr Asp Arg Ser Asp Ala Met Thr Ser Tyr Tyr Ile Asn Val

50 55 60Ile Val Tyr Glu Leu Gln Lys Leu Gly Phe Tyr Asn Val Phe Thr Gln65 70 75 80Ala Glu Phe Pro Leu Asp Lys Ala Lys Asn Val Ile Tyr Val Arg Ile

85 90 95Val Arg Asn Ile Ser Ala Val Pro Phe Tyr Gln Tyr Asn Tyr Gln Leu

100 105 110Ile Asp Gln Val Asn Lys Pro Cys Tyr Phe Leu Gly Gly Gln Phe Tyr

115 120 125Cys Ser Gln Thr Pro Thr Asp Tyr Tyr Ala Ile Asn Gly Phe Ser Glu

130135 140Gln Ile Leu Met Ser Ala Asn Ser His Phe Ile Leu Asp Trp Tyr Asp145 150 155 160Val Val Leu Gln Lys Arg Val Leu Tyr Val Asp Gly Ser Val Ser Gly

165 170 175Arg Thr Cys Gly Tyr Gln Met Leu Tyr Arg Asp Leu Ile Lys Ser Thr

180 185 190Ile Lys Arg Ile Asp Phe Asn Arg Pro Glu Arg Tyr Tyr Tyr Asn Leu

195 200 205Arg Leu Pro Leu Tyr Gln Pro Cys Tyr Arg Gln

210215 (2) SEQ ID NO 1062 message

Sequence properties:

(A) length: 416 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: l. 416

(xi) sequence representation: SEQ ID NO 1062: Met Gln Tyr Lys Lys Asn Lys Lys Arg Tyr Tyr His Leu Ala Leu Gly 151015 Ile Leu Phe Cys Asn Gly Leu Ser Leu Lys Ala Leu Glu Ile Ala Val

20 25 30Lys Pro Phe Gly Tyr Leu Gly Leu Leu Tyr Asn Gln Gly Thr Gln Lys

35 40 45Asn Pro His Ser Tyr Val Gly Ala Leu Ala Arg Leu Gly Val Asp Phe 50 55 60Ser Tyr Ser Asn Gly Trp Ser Phe Gly Ile Gly Ala Ile Gly Ala Trp65 70 75 80Asn Ile Tyr Asn Lys Gln Arg Leu Ala Asn Leu Tyr Ile Ser Leu Gly

85 90 95Asn Phe Phe Gly Asn Pro Asn Asn Val Lys Pro Tyr Leu Ser Ala Gly

100 105 110Asp Val Ser Asp Ala Tyr Leu Gln Tyr Ala Asn Gln Arg Phe Lys Ile

115 120 125Ala Leu Gly Arg Phe Asn Thr Asp Phe Val Asp Phe Asp Trp Ile Gly

130 135 140Gly Asn Ile Gln Gly Val Ser Val Ala Phe Lys Gln Asn Ser Met Arg145 150 155 160Tyr Phe Gly Ile Phe Met Asp Ser Met Leu Tyr Asn Gly His Gln Ile

165 170 175Asn Lys Glu Gln Gly Asn Arg Ile Ala Thr Ser Leu Asn Ala Leu Ala

180 185 190Ser Tyr Asp Pro Val Ser Lys Arg Leu Tyr Val Gly Gly Glu Val Phe

195 200 205Val Leu Gly Ala Glu Tyr Lys Asn Lys Asn Leu Ile Phe Val Pro Phe

210 215 220Ile Leu Thr Asp Thr Arg Leu Pro Leu Pro Thr Gln Asn Val Leu Val225 230 235 240Gln Val Gly Gly Lys Leu Glu Tyr Asp Ala Ser Leu Ala Lys Gly Phe

245 250 255Thr Ser Arg Thr Leu Val His Gly Met Tyr Gln Tyr Gly Asn Thr Asp

260 265 270Ile Thr Thr Ser Ala Lys Asn Ala Gly Leu Phe Leu Ile Asp Gln Thr

275 280 285Phe Lys Tyr Lys Ile Phe Asn Phe Gly Thr Gly Phe Tyr Ile Val Pro

290 295 300Ala Arg Asn Asn Lys Gly Tyr Leu Trp Thr Phe Asn Asp Arg Thr Lys305 310 215 320Phe Tyr Gly Arg Gly Ile Asn Ala Pro Gly Val Pro Ala Ile Tyr Phe

325 330 335Ala Asn Ser Ser Ile Ser Gly Tyr Val Phe Leu Gly Leu Lys Thr Lys

340 345 350Arg Val Arg Leu Asp Ala Met Val Ala Phe Gly Asp Tyr Gln Glu Tyr

355 360 365Ser Leu Met Ser Ser Phe Arg Val Trp Thr Tyr Arg Asp Leu Ser Phe

370 375 380Asp Met Gly Gly Gly Tyr Val Tyr Ala Tyr Asn Ser Lys Ala Thr Arg385 390 395 400Lys Ser Leu Gly Asp Ser Ser Phe Val Phe Phe Gly Lys Phe Leu Phe

405410415 (2) SEQ ID NO 1063 information

Sequence properties:

(A) length: 668 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...668

(xi) sequence representation: SEQ ID NO 1063 Mer Val Lys Asn Thr Lys Gly Ile Gln Gln Leu Ser Glu Asn Tyr Glu 151015 Lys Leu Asn Asn Leu Leu Asn Asn Tyr Asn Thr Leu Asn Thr LeuVal

20 25 30Lys Leu Ser Ser Asp Pro Ser Ala Val Asn Asp Ala Arg Asp Asn Leu

35 40 45Gly Ser Ser Thr Arg Asn Leu Leu Asp Val Lys Ala Asn Ser Pro Ala

50 55 60Tyr Gln Ala Val Leu Leu Ala Leu Asn Ala Ala Val Gly Leu Trp Gln65 70 75 80Val Thr Ser Tyr Ala Phe Thr Ala Cys Gly Pro Gly Ser Asn Glu Asn

85 90 95Ala Asn Gly Gly Ile Gln Thr Phe Asn Asn Val Pro Gly Gln Asn Thr

100 105 110Thr Thr Ile Thr Cys Asn Ser Tyr Tyr Glu Pro Gly His Gly Gly Pro

115 120 125Ile Ser Thr Lys Asn Tyr Ala Ile Ile Asn Lys Ala Tyr Gln Ile Ile

130 135 140Gln Lys Ala Leu Thr Ala Asn Gly Glu Gly Ile Pro Val Leu Ser Asn145 150 155 160Thr Thr Thr Lys Leu Asp Phe Thr Ile Asn Gly Asp Lys Arg Thr Gly

165 170 175Gly Glu Pro Asn Lys Lys Leu Val Tyr Pro Trp Ser His G1y Lys Ala

180 185 190Ile Ser Thr Ser Trp Asn Ala Thr Ile Thr Ala Pro Thr Thr Glu Asn

195 200 205Ile Asn Thr Thr Asn Ser Ala Gln Glu Leu Leu Lys Gln Ala Ser Ile

210 215 220Ile Ile Thr Thr Leu Asn Ser Ala Cys Pro Asn Phe Gln Asn Gly Gly225 230 235 240Ser Gly Tyr Trp Ala Gly Ile Ser Gly Asn Gly Thr Met Cys Gly Met

245 250 255Phe Lys Asn Glu Ile Ser Ala Ile Gln Gly Met Ile Ala Asn Ala Gln

260 265 270Glu Ala Val Ala Gln Ala Lys Ile Val Ser Glu Asn Thr Gln Asn Gln

275 280 285Asn Ser Leu Asp Ala Gly Lys Pro Phe Asn Pro Tyr Thr Asp Ala Ser

290 295 300Phe Ala Glu Ser Met Leu Lys Asn Ala Gln Ala Gln Ala Glu Ile Leu305 310 315 320Asn Gln Ala Glu Gln Val Val Lys Asn Phe Glu Lys Ile Pro Thr Ala

325 330 335Phe Val Asn Asp Ser Leu Gly Val Cys Tyr Glu Val Gln Gly Gly Glu

340 345 350Arg Arg Gly Thr Asn Pro Gly Gln Thr Thr Ser Asn Thr Trp Gly Ala

355 360 365Gly Cys Ala Tyr Val Gly Gln Thr Ile Thr Asn Leu Lys Asn Ser Ile

370 375 380Ala His Phe Gly Thr Gln Glu Gln Gln Ile Gln Gln Ala Glu Asn Ile385 390 395 400Ala Asp Thr Leu Val Asn Phe Lys Ser Arg Tyr Ser Glu Leu Gly Asn

405 410 415Thr Tyr Asn Ser Ile Thr Thr Ala Leu Ser Asn Ile Pro Asn Ala Gln

420 425 430Ser Leu Gln Asn Ala Val Ser Lys Lys Asn Asn Pro Tyr Ser Pro Gln

435 440 445Gly Ile Asp Thr Asn Tyr Tyr Leu Asn Gln Asn Ser Tyr Asn Gln Ile

450 455 460Gln Thr Ile Asn Gln Glu Leu Gly Arg Asn Pro Phe Arg Lys ValGly465 470 475 480Ile Val Ser Ser Gln Thr Asn Asn Gly Ala Met Asn Gly Ile Gly Ile

485 490 495Gln Val Gly Tyr Lys Gln Phe Phe Gly Gln Lys Arg Lys Trp Gly Ala

500 505 510Arg Tyr Tyr Gly Phe Phe Asp Tyr Asn His Ala Phe Ile Lys Ser Ser

515 520 525Phe Phe Asn Ser Ala Ser Asp Val Trp Thr Tyr Gly Phe Gly Ala Asp

530 535 540Ala Leu Tyr Asn Phe Ile Asn Asp Lys Ala Thr Asn Phe Leu Gly Lys545 550 555 560Asn Asn Lys Leu Ser Val Gly Leu Phe Gly Gly Ile Ala Leu Ala Gly

565 570 575Thr Ser Trp Leu Asn Ser Glu Tyr Val Asn Leu Ala Thr Met Asn Asn

580 585 590Val Tyr Asn Ala Lys Met Asn Val Ala Asn Phe Gln Phe Leu Phe Asn

595 600 605Met Gly Val Arg Met Asn Leu Ala Arg Pro Lys Lys Lys Asp Ser Asp

610 615 620His Ala Ala Gln His Gly Ile Glu Leu Gly Leu Lys Ile Pro Thr Ile625 630 635 640Asn Thr Asn Tyr Tyr Ser Phe Met Gly Ala Glu Leu Lys Tyr Arg Arg

645 650 655Leu Tyr Ser Val Tyr Leu Asn Tyr Val Phe Ala Tyr

660665 (2) SEQ ID NO 1064 information

Sequence properties:

(A) length: 342 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...342

(xi) sequence representation: SEQ ID NO 1064: Leu Thr Lys Lys Phe Met Ser Trp Met Val Val Ile Gly Ala Leu Ile 151015 Cys Val Leu Leu Gly Val Phe Ile Phe Phe Thr Ser Met Ser Val Lys

20 25 30Lys Ser Leu Thr Ala Tyr Leu Asn Ala Tyr Leu Glu Gln Arg Pro Asn

35 40 45Ile Glu Gly Met Gly Ile Ile Gly Val Pro Phe Lys Cys Glu Gly Phe

50 55 60Phe Lys Ile Ala Cys Val Ser Lys Glu Leu Arg Phe Leu Asp Pro Gln65 70 75 80Asn Ser Pro Ile Met Asp Phe Lys Asn Leu Lys Ile Lys Leu His Ser

85 90 95Leu Asp Lys Ser Ser Leu Thr Leu Ser Ile His Ser Gln Ile Gln Ser

100 105 110Pro Ile Leu Glu Gln Ser Ile Gln Gln Lys Ile Ser Gln Ile Pro Leu

115 120 125Lys Asn Leu Asn Ala Leu Leu Glu Lys Phe Lys Pro Thr Arg Leu Asn

130 135 140Cys Ser Leu Thr Phe Asn Ala Leu Asp Glu Lys Thr Leu Asn Asp Asn145 150 155 160Leu Lys Cys Asp Leu Thr Asn Ala Glu Asn Ile Leu Ala Tyr Thr Phe

165170 175Phe Gln Glu Gly Leu Met Glu Ala Gln Glu Asn Leu Ser Leu Lys Asn

180 185 190Ile Phe Lys Thr Leu Ser Ser Lys Asp Ala Lys Ala Ile GLu Glu Leu

195 200 205Gln Asp Lys Leu Arg Phe Leu Ala Pro Lys Leu Ser Val Ser Ile Gln

210 215 220Ala Arg His Phe Lys Asn Val Leu Glu Ser Phe Tyr Gln Gln Asn Lys225 230 235 240Glu Ser Leu Gly Phe Phe Ser Pro Tyr Phe Ser Leu Arg Ser Gln Thr

245 250 255Pro Ser Val Ser Tyr Glu Ser Ala Leu Ala Ser Leu Glu Asn Tyr Phe

260 265 270Met Ala Leu Phe Gln Ser His Phe Lys Asp Asp Thr Ala Leu Gln Gln

275 280 285Asn Phe Lys Gly Leu Leu Gln Ala Phe Val Ser Met Ala Lys Asp Lys

290 295 300Arg Ser Gln Ile Val Leu Asn Ala Gln Ala Lys Asp Asn Thr Lys Leu305 310 315 320Thr Phe Asn Ala Leu Leu Glu Ser Leu Ser Val Asn Phe Phe Gln Ser

325 330 335Tyr Lys Ile Ser His Glu

340(2) SEQ ID NO 1065 information

Sequence properties:

(A) length: 293 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...293

(xi) sequence representation: SEQ ID NO:1065: Met Arg Leu Leu Phe Leu Leu Leu Ser Ala Thr Leu Met Leu Leu Ala 151015 Glu Glu Lys Ile Pro Leu Ser Asp Asp Ala Pro Ile Lys Leu Val His

20 25 30Trp Gln Asn Ala Leu Lys Glu Val Gln Pro Asp Ser Asn Ala Pro Ala

35 40 45Thr Pro Pro Ile Lys Ala Val Gln Thr Thr Leu Thr Phe Glu Thr Pro

50 55 60Phe Asn Lys Thr Pro Lys Ile Met Glu Val Glu Gly Gln Lys Val Ile65 70 75 80Val Leu Lys Asn Ala Gln Leu Asp Ser Lys Lys Thr Met Asp Phe Lys

85 90 95Glu Ala Ser Leu Asn Ala Leu Glu Met Phe Ser Tyr Gln Asn Asp Ile

100 105 110Tyr Leu Leu Ser Lys Lys Ala Lys Ala Gly Leu Glu Ile Gln Ala Ser

115 120 125Ser Ser Lys Asp Lys Lys Gln Leu Arg Phe Leu Phe Leu Pro Lys Gly

130 135 140Phe His Leu Ala Pro Pro Pro Ser Leu Lys Glu Lys Ser Gln His Ala145 150 155 160Asn Leu Ala Ser Gln Asp Glu Lys Glu Arg Ala Lys Ser Pro Ser Asn

165 170 175Ala Leu Glu Leu Lys Pro Pro Leu Asp Leu Ser His Ala Tyr Lys Gly

180 185 190LeuAla Val Ile Ala Val Leu Leu Leu Ile Leu Tyr Val Ile Lys Lys

195 200 205Lys Ile Val Pro Thr Pro Gly Ser Phe Leu Lys Lys Asp Leu Lys Leu

210 215 220Asp Ile Ser Val Leu Gly Arg Val Asp Ala Asn His Lys Ile Ile Ser225 230 235 240Ile Glu Thr Asn Lys Glu Arg Tyr Leu Val Leu Leu Ser Asp Lys Tyr

245 250 255Gly Leu Leu Leu Asp Lys Ile Ser Pro Lys Thr Ser Lys Glu Glu Leu

260 265 270Ile Lys Glu Ala Glu Asn Lys Ile Lys Asn Ser Lys Leu Gly Asn Leu

275 280 285Tyr Ala Gly Lys Phe

290(2) SEQ ID NO 1066 information

Sequence properties:

(A) length: 286 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...286

(xi) sequence representation: SEQ ID NO 1066: Met Leu Arg Asn Gln Phe Arg Ile Val Phe Val Ser Cys Ile Val Ala 151015 Ser Ser Leu Gln Ala Gln Glu Asn Thr His Thr Leu Gly Lys Val Thr

20 25 30Thr Lys Gly Glu Arg Thr Phe Glu Tyr Asn Asn LysMet Tyr Ile Asp

35 40 45Arg Lys Glu Leu Gln Gln Arg Gln Ser Asn Gln Ile Arg Asp Ile Phe

50 55 60Arg Thr Arg Ala Asp Val Asn Val Ala Ser G1y Gly Leu Met Ala Gln65 70 75 80Lys Ile Tyr Val Arg Gly Ile Glu Ser Arg Leu Leu Arg Val Thr Ile

85 90 95Asp Gly Val Ala Gln Asn Gly Asn Ile Phe His His Asp Ala Asn Thr

100 105 110Val Ile Asp Pro Asn Met Ile Lys Glu Val Glu Val Ile Lys Gly Ala

115 120 125Ala Asn Ala Ser Ala Gly Pro Gly Ala Val Ala G1y Lys Leu Ser Phe

130 135 140Thr Thr Ile Asp Ala Asn Asp Phe Leu Arg Lys Asn Gln Thr Tyr Gly145 150 155 160Ala Lys Ala Glu Ala Ala Phe Tyr Thr Asn Phe G1y Tyr Arg Met Asn

165 170 175Ala Thr Ala Ala Tyr Arg Gly Lys Asn Trp Asp Ile Leu Ala Tyr Tyr

180 185 190Asn His Gln Asn Ile Phe Tyr Tyr Arg Asp Gly Asn Asn Ala Phe Arg

195 200 205Ser Leu Phe His Pro Asn Tyr Asp Leu Gln Asp Pro Ser Asn Ser Glu

210 215 220Met Ser Val Gly Thr Pro Ser Glu Val Asn Ser Val Leu Ala Lys Ile225 230 235 240Asn Gly Tyr Ile Asn Glu Thr Asp Ser Ile Ser Val Ser Tyr Asn Leu

245 250 255Thr Arg Asp Asn Ser Thr Arg Leu Leu Arg Pro Asn Thr Thr Ser Ala

260 265 270Leu Ser Lys Ala Asn Asp Gln Glu Ala Ser Gln Pro Pro Leu

275280285 (2) SEQ ID NO 1067 information

Sequence properties:

(A) length: 341 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...341

(xi) sequence representation: SEQ ID NO 1067: Met Lys Arg Leu Leu Leu Leu Ala Leu Ala Leu Phe Phe Ser Leu Ser 151015 Cys Thr Asn Ala Gln Glu Ile Lys Glu Thr Gln Glu Thr Lys Lys Thr

20 25 30Lys Glu Thr Lys Ser Gln Thr Arg Phe Asn Ile Ser Thr Thr Lys Val

35 40 45Ile Glu Lys Glu Phe Ser Gln Ser Arg Arg Tyr Tyr Ala Leu Leu Glu

50 55 60Pro Asn Glu Ala Leu Ile Phe Ser Gln Thr Leu Arg Phe Asp Gly Tyr65 70 75 80Val Glu Lys Leu Tyr Ala Asn Lys Thr Tyr Thr Pro Ile Lys Lys Gly

85 90 95Asp Arg Leu Leu Ser Val Tyr Ser Pro Glu Leu Ala Gly Val Gln Ser

100 105 110Glu Leu Leu Ser Ser Leu Lys Phe Asn Gln Gln Val Gly Ala Ile Lys

115 120 125Glu Lys Leu Lys Leu Leu Gly Leu Glu Asn Phe Ser Ile Glu Lys Ile

130 135 140Ile Ser Ser His Lys Val Gln Asn Glu Ile Thr Ile Tyr Ser Arg Phe145 150 155 160Asn Gly Val Ile Phe Lys Lys Ser Pro Asp Leu Asn Glu Gly Ser Phe

165 170 175Ile Lys Lys Gly Gln Glu Leu Phe Lys Ile Ile Asp Leu Ser Arg Leu

180 185 190Trp Ala Leu Val Lys Val Asn Gln Glu Asp Leu Glu Phe Leu Lys Asn

195 200 205Thr His Gln Ala Ile Leu Phe Val Glu Gly Val Lys Gly Lys Gln Ala

210 215 220Ile Thr Leu Glu Asn Ile Asn Pro Ile Ile Asn Ala Gln Asp Lys Met225 230 235 240Leu Glu Ala Arg Phe Asn Val Pro Asn Leu Lys Leu Leu Tyr Tyr Pro

245 250 255Asn Met Phe Ala Gln Val Glu Ile Phe His Lys Pro Gln Lys Met Lys

260 265 270Ile Leu Pro Lys Glu Ala Val Leu Ile Lys Gly Gly Lys Ala Ile Val

275 280 285Phe Lys Lys Asp Asp Phe Gly Leu Ser Pro Leu Glu Ile Lys Ala Val

290 295 300Arg Leu Ser Asp Gly Ser Tyr Glu Ile Leu Glu Gly Leu Lys Ala Gly305 310 315 320Glu Glu Val Ala Asn Asn Ala Leu Phe Val Leu Asp Ala Asp Ala Gln

325 330 335Asn Asn Gly Asp Tyr

340(2) SEQID NO 1068 message

Sequence properties:

(A) length: 463 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...463

(xi) sequence representation: SEQ ID NO 1068 Met Ala Phe Cys Ala Arg Gln Lys Pro Leu Lys Glu Ile Met Arg Phe 151015 Phe Ile Leu Phe Phe Met Gly Met Leu Gly Val Gly Phe Ser Gln Thr

20 25 30Glu Leu Asp Leu Lys Asp Leu Glu Lys Lys Pro Ala Gly Ile Val Arg

35 40 45Asp Tyr Tyr Leu Trp Arg Tyr Ile Ser Asp Lys Lys Thr Sar Leu Glu

50 55 60Asn Ala Lys Lys Ala Tyr Glu Leu Thr Gln Asn Lys Asn Ser Ala Leu65 70 75 80Gln Lys Ala Met Gln Glu Lys Gly Val Glu Asn Ser Asp Lys Ser Pro

85 90 95Asp Ala Lys Met Pro Glu Asp Ile Tyr Cys Lys Gln Ile Thr Leu Glu

100 105 110Ser Met Leu Glu Thr Thr Asp Ala Phe Gln Ala Ser Cys Ile Ala Ile

115 120 125Ala Leu Lys Ser Lys Ile Arg Asp Phe Asp Lys Ile Pro Ile Gln Thr

130 135 140Phe Lys Pro Leu Gln Glu Lys Ile Lys Glu Ala Tyr Pro Ile Leu Tyr145 150 155 160Glu Glu Leu Glu Ile Leu Gln Ser Lys Asn Val Ser Ala Ser Leu Phe

165 170 175Lys Ala Asn Ala Gln Val Phe Ser Ala Leu Phe Ash His Leu Ser Tyr

180 185 190Glu Lys Lys Leu Gln Ile Phe Glu Lys His Ile Pro Ile Lys Glu Leu

195 200 205Asn Arg Leu Leu Asp Glu Asp Tyr Pro Ala Phe Asn Arg Leu Ile Tyr

210 215 220Gln Val Ile Leu Asp Pro Lys Leu Asp His Phe Lys Asp Ala Leu Ala225 230 235 240Lys Ser Asn Ala Thr Gln Ser Asn Ala Gln Thr Phe Phe Ile Leu Gly

245 250 255Ile Asn Glu Ile Leu His Lys Lys Thr Ser Lys Ala Leu Lys Tyr Phe

260 265 270Glu Arg Ser Glu Ala Val Val Lys Asp Asp Asp Phe Ser Lys Asp Arg

275 280 285Ala Ile Phe Trp Gln Tyr Leu Ala Ser Lys Lys Lys Lys Thr Leu Glu

290 295 300His Leu Ser Gln Ser Pro Ala Leu Asn Leu Tyr Ser Leu Tyr Ala Ser305 310 315 320Arg Lys Leu Lys Thr Thr Pro Ser Tyr Arg Ile Ile Ser His Ile Gln

325 330 335Asn Leu Ser Gln Glu Asn Pro Pro Phe Asn Thr Tyr Asp Pro Phe Ser

340 345 350Trp Gln Ile Phe Lys Glu Lys Thr Leu Ser Leu Lys Asp Glu Gly Ala

355 360365Phe Asn Ala Met Leu Lys Ser Leu Tyr Tyr Glu Lys Ser Ala Pro Glu

370 375 380Leu Thr Tyr Leu Leu Ser Gln Arg Asn Lys Asp Lys Ile Tyr Tyr Tyr385 390 395 400Leu Ser Pro Tyr Glu Gly Ile Ile Glu Trp Gln Asn Thr Asp Glu Arg

405 410 415Ala Met Ala Tyr Ala Ile Ala Arg Gln Glu Ser Phe Leu Leu Pro Ala

420 425 430Leu Ile Ser Arg Ser Phe Ala Leu Gly Leu Met Gln Ile Met Pro Phe

435 440 445Asn Val Gly Pro Phe Ala Lys Ala Leu Ala Trp Ile Met Leu Ile

450455460 (2) SEQ ID NO 1069 information

Sequence properties:

(A) length: 374 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...374

(xi) sequence representation: SEQ ID NO. 1069: Met Pro Lys Arg Met Lys Cys Phe Ser Gln Lys Trp Leu Val Phe Phe 151015 Val Thr His Trp Leu Leu Leu Ala Ser Leu Ser His Ala Lys Met Ala

20 25 30Phe Glu Ser Asn Ile Asp Thr Lys Ala Leu Glu Ala Phe Gly Val Asn

35 40 45Ala Ser Phe Leu Ser Gln Met Pro Gly Ala Leu Lys Lys Val Asn Lys

50 55 60Glu Glu Glu Trp Lys Lys Leu Val Lys Arg Phe Asp Val Asn Tyr Gln65 70 75 80Phe Ile Pro Ile Ile Lys Asn Met Leu Ile Gly Ala Ser Val Pro Gln

85 90 95Glu Phe Leu Phe Leu Ala Met Ala Glu Ser Lys Phe Ser Ser Arg Ala

100 105 110Tyr Ser Arg Lys Lys Ala Val Gly Ile Trp Gln Phe Met Pro Ser Thr

115 120 125Ala Lys Glu Leu Gly Leu Lys Val Asn His Tyr Ile Asp Glu Arg Arg

130 135 140Asp Pro Ile Lys Ser Thr Gln Ala Ala Ile Ala Tyr Leu Lys Arg Leu145 150 155 160Tyr Lys Gln Thr Gly Glu Trp Tyr Leu Val Ala Met Ala Tyr Asn Tyr

165 170 175Gly Leu Arg Lys Val Gln Asn Ala Ile Lys Ala Ala Gly Thr Ser Asp

180 185 190Ile Lys Val Leu Leu Asp Glu Asp Lys Lys Tyr Leu Pro Lys Glu Thr

195 200 205Arg Glu Tyr Ile Arg Ser Ile Leu Ser Leu Ala Leu Lys Phe Asn Ser

210 215 220Leu Asp Asn Leu Lys Asp Lys Glu Tyr Leu Leu Asn Arg Gly Ala Arg225 230 255 240Val Ser Leu Val Gly Val Pro Phe Lys Arg His Thr Ser Leu Val Gln

245 250 255Val Ala Lys Asn Leu Asn Leu Ser Leu Glu Thr Leu Lys Ser Tyr Asn

260 265 270His Gln PheArg Tyr Asn Ile Leu Pro Ser Lys Asp Pro Thr Tyr Thr

275 280 285Ile Tyr Ile Pro Tyr Glu Lys Leu Ala Leu Phe Lys Gln Arg Gln Leu

290 295 300Lys Gln Asn Lys Asn Ala Gln Ala Asn Pro Lys Ser Pro Phe Ile Thr305 310 315 320His Val Val Leu Pro Lys Glu Thr Leu Ser Ser Ile Ala Lys Arg Tyr

325 330 335Gln Val Ser Ile Ser Ser Ile Gln Leu Ala Asn Asn Leu Lys Asp Ser

340 345 350Asn Ile Phe Ile His Gln Arg Leu Ile Ile Pro Thr Asn Lys Lys Leu

355 360 365Leu Ala Thr Arg Glu Phe

370(2) SEQ ID NO 1070 information

Sequence properties:

(A) length: 333 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...333

(xi) sequence representation: SEQ ID NO 1070: Met Leu Ile Ala Arg Phe Lys Lys Ala Leu Ile Ser Tyr Ser Leu Gly 151015 Val Leu Leu Val Ser Ser Leu Leu Gly Val Ala Asn Ala Ser Asn Gln

20 25 30Glu Ile Gln Val Lys Asp Tyr Phe Gly Glu GlnThr Ile Lys Leu Pro

35 40 45Val Ser Lys Ile Ile Tyr Leu Gly Ser Phe Ala Glu Val Pro Ala Met

50 55 60Phe Asn Thr Trp Asp Arg Val Val Gly Ile Ser Asp Tyr Ala Phe Lys65 70 75 80Ser Asp Ile Val Lys Ala Thr Leu Lys Asp Pro Glu Arg Ile Lys Pro

85 90 95Met Ser Ser Asp His Val Ala Ala Leu Asn Val Glu Leu Leu Lys Lys

100 105 110Leu Ser Pro Asp Leu Val Val Thr Phe Val Gly Asn Pro Lys Ala Val

115 120 125Glu His Ala Lys Lys Phe Gly Ile Ser Phe Leu Ser Phe Gln Glu Lys

130 135 140Thr Ile Val Glu Val Met Glu Asp Ile Asp Ala Gln Ala Lys Ala Leu145 150 155 160Glu Val Asp Ala Ser Lys Lys Leu Ala Lys Met Gln Glu Thr Leu Asp

165 170 175Phe Ile Lys Glu Arg Leu Lys Asn Val Lys Lys Lys Lys Gly Val Glu

180 185 190Leu Phe His Lys Ala Asn Lys Ile Ser Gly His Gln Ala Leu Asp Ser

195 200 205Asp Ile Leu Glu Lys Gly Gly Ile Asp Asn Phe Gly Leu Lys Tyr Val

210 215 220Lys Phe Gly Arg Ala Asp Ile Ser Val Glu Lys Ile Val Lys Glu Asn225 230 235 240Pro Glu Ile Ile Phe Ile Trp Trp Ile Ser Pro Leu Ser Pro Glu Asp

245 250 255Val Leu Asn Asn Pro Lys Phe Ser Thr Ile Lys Ala Ile Lys Asn Lys

260 265 270Gln Val Tyr Lys Leu Pro Thr Met Asp Ile Gly Gly Pro Arg Ala Pro

275 280 285Leu Ile Ser Leu Phe Ile Ala Leu Lys Ala His Pro Glu Ala Phe Lys

290 295 300Gly Val Asp Ile Asn Ala Ile Ile Lys Asp Tyr Tyr Lys Val Val Phe305 310 315 320Asp Leu Asn Asp Ala Glu Val Glu Pro Phe Leu Trp His

325330 (2) SEQ ID NO 1071 information

Sequence properties:

(A) length: 533 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...533

(xi) sequence representation: SEQ ID NO 1071: Met Glu Ile Arg Asn Ile Lys Glu Phe Glu Lys Ala Ser Lys Lys Leu 151015 Gln Lys Asp Thr Leu Lys Ile Ala Leu Ala Leu Leu Phe Leu Ile Gly

20 25 30Ala Ala Leu Leu Ala Leu Ile Phe Gly Gln Ala Asn Ser Lys Gly Leu

35 40 45Leu Leu Ile Phe Ala Ala Val Ile Gly Gly Tyr Met Ala Met Asn Ile

50 55 60Gly Ala Asn Asp Val Ser Asn Asn Val Gly Pro Ala Val Gly Ser Lys65 7075 80Ala Ile Ser Met Gly Gly Ala Ile Leu Ile Ala Ala Val Cys Glu Met

85 90 95Leu Gly Ala Ile Ile Ala Gly Gly Glu Val Val Ser Thr Ile Lys Gly

100 105 110Arg Ile Val Ser Pro Glu Phe Ile Asn Asp Ala His Val Phe Ile Asn

115 120 125Val Met Leu Ala Ser Leu Leu Ser Gly Ala Leu Trp Leu His Val Ala

130 135 140Thr Leu Ile Gly Ala Pro Val Ser Thr Ser His Ser Val Val Gly Gly145 150 155 160Ile Met Gly Ala Gly Met Ala Ala Ala Gly Met Ser Ala Ile Asn Trp

165 170 175His Phe Leu Ser Gly Ile Val Ala Ser Trp Val Ile Ser Pro Leu Met

180 185 190Gly Ala Leu Ile Ala Met Phe Phe Leu Met Leu Ile Lys Lys Thr Ile

195 200 205Ala Tyr Lys Glu Asp Lys Lys Ser Ala Ala Leu Lys Val Val Pro Tyr

210 215 220Leu Val Ala Leu Met Ser Leu Ala Phe Ser Trp Tyr Leu Ile Val Lys225 230 235 240Val Leu Lys Arg Leu Tyr Ala Val Gly Phe Glu Ile Gln Leu Ala Cys

245 250 255Gly Cys Val Leu Ala Leu Leu Ile Phe Ile Leu Phe Lys Arg Phe Val

260 265 270Leu Lys Lys Ala Pro Gln Leu Glu Asn Ser His Glu Ser Val Asn Glu

275 280 285Leu Phe Asn Val Pro Leu Ile Phe Ala Ala Ala Leu Leu Ser Phe Ala

290 295 300His Gly Ala Asn Asp Val Ala Asn Ala Ile Gly Pro Leu Ala Ala Ile305 310 315 320Ser Gln Thr Leu Glu Asp Ala Ser Ser Pro Met Gly Ser Thr Leu Asn

325 330 335Ser Val Pro Leu Trp Ile Met Val Val Gly Ala Ala Gly Ile Ala Leu

340 345 350Gly Leu Ser Leu Tyr Gly Pro Lys Leu Ile Lys Thr Val Gly Ser Glu

355 360 365Ile Thr Glu Leu Asp Lys Met Gln Ala Phe Cys Ile Ala Leu Ser Ala

370 375 380Val Ile Thr Val Leu Leu Ala Ser Gln Leu Gly Leu Pro Val Ser Ser385 390 395 400Thr His Ile Val Val Gly Ala Val Phe Gly Val Gly Phe Leu Arg Glu

405 410 415Arg Leu Arg Glu Gln Ser Arg Arg Arg Phe Ala Arg Ile Arg Asp Asn

420 425 430Ile Val Ala Ala His Phe Gly Glu Asp Leu Glu Glu Ile Glu Gly Phe

435 440 445Leu Glu Arg Phe Asp Lys Ala Asn Leu Lys Glu Lys Ser Leu Met Leu

450 455 460Glu Ser Leu Lys Lys Ser Lys Asn Thr Ala Ile Ala Leu Glu Leu Lys465 470 475 480Lys Lys Glu Lys Lys Ser Leu Lys Lys Val Tyr Lys Glu Glu Val Ile

485 490 495Lys Arg Ser Ile Leu Lys Lys Ile Val Thr Ala Trp Leu Val Thr Val

500 505 510Pro Val Ser Ala Leu Leu Gly Ala Leu Leu Phe Val Ala Leu Gly Phe

515 520 525Ile Glu Lys Tyr Phe

530(2) SEQ ID NO 1072 message

Sequence properties:

(A) length: 329 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...329

(xi) sequence representation: SEQ ID NO 1072: Met Ser Asn Ser Met Leu Asp Lys Asn Lys Ala Ile Leu Thr Gly Gly 151015 Gly Ala Leu Leu Leu Gly Leu Ile Val Leu Phe Tyr Leu Ala Tyr Arg

20 25 30Pro Lys Ala Glu Val Leu Gln Gly Phe Leu Glu Ala Arg Glu Tyr Ser

35 40 45Val Ser Ser Lys Val Pro Gly Arg Ile Glu Lys Val Phe Val Lys Lys

50 55 60Gly Asp Arg Ile Lys Lys Gly Asp Leu Val Phe Ser Ile Ser Ser Pro65 70 75 80Glu Leu Glu Ala Lys Leu Ala Gln Ala Glu Ala Gly His Lys Ala Ala

85 90 95Lys Ala Val Ser Asp Glu Val Lys Arg Gly Ser Arg Asp Glu Thr Ile

100 105 110Asn Ser Ala Arg Asp Val Trp Gln Ala Ala Lys Ser Gln Ala Asn Leu

115 120125Ala Lys Glu Thr Tyr Lys Arg Val Gln Asp Leu Tyr Asp Asn Gly Val

130 135 140Ala Ser Leu Gln Lys Arg Asp Glu Ala Tyr Ala Ala Tyr Glu Ser Thr145 150 155 160Lys Tyr Asn Glu Ser Ala Ala Tyr Gln Lys Tyr Lys Met Ala Leu Gly

165 170 175Gly Ala Ser Ser Glu Ser Lys Ile Ala Ala Lys Ala Lys Glu Ser Ala

180 185 190Ala Leu Gly Gln Val Asn Glu Val Glu Ser Tyr Leu Lys Asp Val Lys

195 200 205Ala Leu Ala Pro Ile Asp Gly Glu Val Ser Asn Val Leu Leu Ser Gly

210 215 220Gly Glu Leu Ser Pro Lys Gly Phe Pro Val Val Leu Met Ile Asp Leu225 230 235 240Lys Asp Ser Trp Leu Lys Ile Ser Val Pro Glu Lys Tyr Leu Asn Glu

245 250 255Phe Lys Val Gly Lys Glu Phe Glu Gly Tyr Ile Pro Ala Leu Lys Arg

260 265 270Ser Ala Lys Phe Arg Val Lys Tyr Leu Ser Val Met Gly Asp Phe Ala

275 290 285Thr Trp Lys Ala Thr Asn Asn Ser Asn Thr Tyr Asp Met Lys Ser Tyr

290 295 300Glu Val Glu Ala Ile Pro Leu Glu Glu Leu Glu Asn Phe Arg Val Gly305 310 315 320Met Ser Val Leu Val Thr Ile Lys Pro

325(2) SEQ ID NO 1073 information

Sequence properties:

(A) length: 292 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...292

(xi) sequence representation: SEQ ID NO 1073: Arg Leu Glu Ser Pro Leu His Ser Gly Phe Ser Pro Ser Ala Ala Leu 151015 Val Ile Ser Pro Ile Glu Pro Leu Ser Leu Lys Ile Thr Tyr Ser Gln

20 25 30Val Thr Arg Gly Val Met Pro Gly Asp Gly Val Tyr Met Arg Gln Asn

35 40 45Asp Leu Arg Tyr Ala Lys Asn Ile Lys Pro Glu Val Gly Ser Asn Ala

50 55 60Glu Phe Asn Ile Asp Tyr Ser Ser Gln Tyr Phe Ser Gly Arg Ala Ala65 70 75 80Ala Phe Tyr Gln Ala Leu Asp Asn Phe Ile Ser Gln Tyr Ala Gln Arg

85 90 95Leu Ile Val Thr Asn Leu Ser Gln Ala Ile Arg Ile Tyr Gly Tyr Glu

100 105 110Val Gly Gly Thr Phe Arg Tyr Lys Gly Val Ser Leu Asn Val Gly Ile

115 120 125Ser Arg Thr Trp Pro Thr Thr Arg Gly Tyr Leu Met Ala Asp Ser Tyr

130 135 140Glu Leu Ala Ala Ser Thr Gly Asn Val Phe Ile Ile Lys Leu Asp Tyr145 150 155 160Thr Ile Pro Lys Thr Gly Ile Asn Leu Ala Trp Leu Ser Arg Phe Val

165 170 175Thr Gly Leu Asp Tyr Cys Gly Phe Asp Ile Tyr Leu Pro Asp Tyr Gly

180 185 190Thr Ala Glu Lys Pro Lys Thr Pro Thr Asp Leu Ala Lys Cys Gly Ser

195 200 205Gln Leu Gly Leu Val His Met His Lys Pro Gly Tyr Gly Val Ser Asn

210 215 220Phe Tyr Ile Asn Trp Ser Pro Lys Thr Lys Ser His Trp Lys Gly Leu225 230 235 240Leu Leu Ser Ala Val Phe Asn Asn Val Phe Asn Lys Phe Tyr Val Asp

245 250 255Gln Thr Ser Pro Tyr Val Met Ser Pro Asp Met Pro Gly Thr Asp Ala

260 265 270Ile Lys Arg Ala Ile Ala Glu Pro Gly Phe Asn Ala Arg Phe Glu Val

275 280 285Ala Tyr Lys Trp

290(2) SEQ ID NO 1074 message

Sequence properties:

(A) length: 484 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...484

(xi) sequence representation: SEQ ID NO 1074: Met Ala Lys Ile Thr Thr Val Ile Asp Ile Gly Ser AsnSer Val Arg 151015 Leu Ala Val Phe Lys Lys Thr Ser Gln Phe Gly Phe Tyr Leu Leu Phe

20 25 30Glu Thr Lys Ser Lys Val Arg Ile Ser Glu Gly Cys Tyr Ala Phe Lys

35 40 45Gly Val Leu Gln Glu Ile Pro Mer Gln Arg Ala Val Lys Ala Leu Ser

50 55 60Glu Phe Lys Glu Ile Ala Leu Lys Tyr Lys Ser Lys Lys Ile Leu Cys65 70 75 80Val Ala Thr Ser Ala Val Arg Asp Ala Pro Asn Arg Leu Glu Phe Val

85 90 95Ala Arg Val Lys Lys Ala Cys Gly Leu Gln Ile Lys Ile Ile Asp Gly

100 105 110Gln Lys Glu Ala Leu Tyr Gly Gly Ile Ala Cys Ala Asn Leu Leu His

115 120 125Lys Asn Ser Gly Ile Thr Ile Asp Ile Gly Gly Gly Ser Thr Glu Cys

130 135 140Ala Leu Ile Glu Lys Gly Lys Ile Lys Asp Leu Ile Ser Leu Asp Val145 150 155 160Gly Thr Ile Arg Ile Lys Glu Met Phe Leu Asp Lys Asp Leu Asp Val

165 170 175Lys Leu Ala Lys Ala Phe Ile Gln Lys Glu Val Ser Lys Leu Pro Phe

180 185 190Lys His Lys Asn Ala Phe Gly Val Gly Gly Thr Ile Arg Ala Leu Ser

195 200 205Lys Val Leu Met Lys Arg Phe Asp Tyr Pro Ile Asp Ser Leu His Gly

210 215 220Tyr Glu Ile Asp Ala His Lys Asn Leu Ala Phe Ile Glu Lys Ile Val225 230 235240Met Leu Lys Glu Asp Lys Leu Arg Leu Leu Gly Val Asn Glu Glu Arg

245 250 255Leu Asp Ser Ile Arg Ser Gly Ala Leu Ile Leu Ser Val Val Leu Glu

260 265 270His Leu Lys Thr Ser Leu Met Ile Thr Ser Gly Val Gly Val Arg Glu

275 280 285Gly Val Phe Leu Ser Asp Leu Leu Arg His His Tyr His Lys Phe Pro

290 295 300Pro Asn Ile Asn Pro Ser Leu Ile Ser Leu Lys Asp Arg Phe Leu Pro305 310 315 320His Glu Lys His Ser Gln Lys Val Lys Lys Glu Cys Val Lys Leu Phe

325 330 335Glu Val Leu Ser Pro Leu His Lys Ile Asp Glu Lys Tyr Leu Phe His

340 345 350Leu Lys Ile Ala Gly Glu Leu Ala Ser Met Gly Lys Ile Leu Ser Val

355 360 365Tyr Leu Ala His Lys His Ser Ala Tyr Phe Ile Leu Asn Ala Leu Ser

370 375 380Tyr Gly Phe Ser His Gln Asp Arg Ala Ile Ile Cys Leu Leu Ala Gln385 390 395 400Phe Ser His Lys Lys Ile Pro Lys Asp Asn Ala Ile Ala His Met Ser

405 410 415Ala Met Met Pro Ser Leu Leu Thr Leu Gln Trp Leu Ser Phe Ile Leu

420 425 430Ser Leu Ala Glu Asn Leu Cys Leu Thr Asp Ser His His Leu Lys Tyr

435 440 445Thr Leu Glu Lys Asn Lys Leu Val Ile His Ser Asn Asp Ala Leu Tyr

450455460 Leu Ala Lys GluMet Leu Pro Lys Leu Ile Lys Pro Ile Pro Leu Thr 465470475480 Ile Glu Phe Ala (2) SEQ ID NO:1075 information

Sequence properties:

(A) length: 222 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...222

(xi) sequence representation: SEQ ID NO 1075: Met Val Gly Met Lys Thr Glu Met Lys Ser Phe Leu Lys Leu Phe Ala 151015 Gln Pro Leu Leu Val Val Leu Ala Phe Met Leu Leu Tyr Ala Leu Ala

20 25 30His Ala Val Leu Gly Phe Tyr Val Lys Lys Asp Ser Ala Pro Met Ser

35 40 45Pro Asn Val Glu Lys Ser Glu Thr Glu Arg Gln Asn Ser Thr Phe Ser

50 55 60Pro Lys Glu Glu Ala Asn Ala Thr Thr Thr Ala Thr Glu Gln Asn Pro65 70 75 80Thr Lys Asp Thr Val Pro Pro Leu Asp Thr Ala Thr Gln Lys Gln Glu

85 90 95Ile Lys Gln Glu Ile Lys Gln Glu Ile Lys Gln Glu Ile Lys Gln Glu

100 105 110Ile Lys Gln Glu Ile Lys Gln Glu Ile Lys Gln Glu Thr Lys Gln Glu

115 120 125Gln Glu Lys Glu Asn Lys Pro Lys Gln Asn Ser Val Ser Pro Val Gln

130 135 140Asn Asp Gln Lys Thr Pro Thr Thr Pro Leu Met Gly Lys Lys Pro Leu145 150 155 160Glu Tyr Lys Val Ala Val Ser Gly Val Asn Val Arg Ala Phe Pro Ser

165 170 175Thr Lys Gly Lys Ile Ile Gly Ser Leu Ile Lys Asn Lys Ser Val Lys

180 185 190Val Leu Glu Ile Gln Asn Asp Trp Ala Glu Ile Glu Phe Ser His Glu

195 200 205Thr Lys Gly Tyr Val Phe Leu Lys Leu Leu Lys Lys Ala Glu

210215220 (2) SEQ ID NO 1076 information

Sequence properties:

(A) length: 135 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...135

(xi) sequence representation: SEQ ID NO 1076: Glu Pro Asp Ala Thr Ser Arg Arg Thr Leu Asn His Pro Tyr Phe Gly 151015 Val Phe Val Leu Leu Val Phe Thr Phe Trp Val Phe Asn Leu Thr Leu

20 25 30Arg Ile Gln Arg Phe Leu Ser Arg Lys Met Ala Gln Lys Lys Gly Glu

35 40 45Lys Leu Lys Leu Ala Pro Tyr Glu Cys Gly Pro Val Ala Leu Lys Gln

50 55 60Pro Asn Arg Val Ser His His Phe Tyr Ile Met Ala Met Leu Phe Ile65 70 75 80Leu Phe Asp Val Glu Ile Val Phe Met Phe Pro Trp Ala Ile Asp Phe

85 90 95Lys Lys Leu Gly Leu Phe Gly Leu Val Glu Met Leu Gly Phe Val Phe

100 105 110Phe Leu Ala Ile Gly Phe Ile Tyr Ala Leu Lys Arg Asn Ala Leu Ser

115 120 125Trp Gln Lys Leu Glu Val Lys

130135 (2) SEQ ID NO 1077 message

Sequence properties:

(A) length: 635 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...635

(xi) sequence representation: SEQ ID NO 1077: Leu Ser Ser Asp Pro Ser Ala Val Asn Asp Ala Arg Asp Asn Leu Gly 151015 Ser Ser Thr Arg Asn Leu Leu Asp Val Lys Ala Asn Ser Pro Ala Tyr

20 25 30Gln Ala Val Leu Leu Ala Leu Asn Ala Ala Val Gly Leu Trp Gln Val

35 40 45Thr Ser Tyr Ala Phe Thr Ala Cys Gly Pro Gly Ser Asn Glu AsnAla

50 55 60Asn Gly Gly Ile Gln Thr Phe Asn Asn Val Pro Gly Gln Asn Thr Thr65 70 75 80Thr Ile Thr Cys Asn Ser Tyr Tyr Glu Pro Gly His Gly Gly Pro Ile

85 90 95Ser Thr Lys Asn Tyr Ala Ile Ile Asn Lys Ala Tyr Gln Ile Ile Gln

100 105 110Lys Ala Leu Thr Ala Asn Gly Glu Gly Ile Pro Val Leu Ser Asn Thr

115 120 125Thr Thr Lys Leu Asp Phe Thr Ile Asn Gly Asp Lys Arg Thr Gly Gly

130 135 140Glu Pro Asn Lys Lys Leu Val Tyr Pro Trp Ser His Gly Lys Ala Ile145 150 155 160Ser Thr Ser Trp Asn Ala Thr Ile Thr Ala Pro Thr Thr Glu Asn Ile

165 170 175Asn Thr Thr Asn Ser Ala Gln Glu Leu Leu Lys Gln Ala Ser Ile Ile

180 185 190Ile Thr Thr Leu Asn Ser Ala Cys Pro Asn Phe Gln Asn Gly Gly Ser

195 200 205Gly Tyr Trp Ala Gly Ile Ser Gly Asn Gly Thr Met Cys Gly Met Phe

210 215 220Lys Asn Glu Ile Ser Ala Ile Gln Gly Met Ile Ala Asn Ala Gln Glu225 230 235 240Ala Val Ala Gln Ala Lys Ile Val Ser Glu Asn Thr Gln Asn Gln Asn

245 250 255Ser Leu Asp Ala Gly Lys Pro Phe Asn Pro Tyr Thr Asp Ala Ser Phe

260 265 270Ala Glu Ser Met Leu Lys Asn Ala Gln Ala Gln Ala Glu Ile Leu Asn

275 280 285Gln Ala Glu Gln Val Val Lys Asn Phe Glu Lys Ile Pro Thr Ala Phe

290 295 300Val Asn Asp Ser Leu Gly Val Cys Tyr Glu Val Gln Gly Gly Glu Arg305 310 315 320Arg Gly Thr Asn Pro Gly Gln Thr Thr Ser Asn Thr Trp Gly Ala Gly

325 330 335Cys Ala Tyr Val Gly Gln Thr Ile Thr Asn Leu Lys Asn Ser Ile Ala

340 345 350His Phe Gly Thr Gln Glu Gln Gln Ile Gln Gln Ala Glu Asn Ile Ala

355 360 365Asp Thr Leu Val Asn Phe Lys Ser Arg Tyr Ser Glu Leu Gly Asn Thr

370 375 380Tyr Asn Ser Ile Thr Thr Ala Leu Ser Asn Ile Pro Asn Ala Gln Ser385 390 395 400Leu Gln Asn Ala Val Ser Lys Lys Asn Asn Pro Tyr Ser Pro Gln Gly

405 410 415Ile Asp Thr Asn Tyr Tyr Leu Asn Gln Asn Ser Tyr Asn Gln Ile Gln

420 425 430Thr Ile Asn Gln Glu Leu Gly Arg Asn Pro Phe Arg Lys Val Gly Ile

435 440 445Val Ser Ser Gln Thr Asn Asn Gly Ala Met Asn Gly Ile Gly Ile Gln

450 455 460Val Gly Tyr Lys Gln Phe Phe Gly Gln Lys Arg Lys Trp Gly Ala Arg465 470 475 480Tyr Tyr Gly Phe Phe Asp Tyr Asn His Ala Phe Ile Lys Ser Ser Phe

485 490 495Phe Asn Ser Ala Ser Asp Val Trp Thr Tyr Gly Phe Gly Ala Asp Ala

500 505 510Leu Tyr Asn Phe Ile Asn Asp Lys Ala Thr Asn Phe Leu Gly Lys Asn

515 520 525Asn Lys Leu Ser Val Gly Leu Phe Gly Gly Ile Ala Leu Ala Gly Thr

530 535 540Ser Trp Leu Asn Ser Glu Tyr Val Asn Leu Ala Thr Met Asn Asn Val545 550 555 560Tyr Asn Ala Lys Met Asn Val Ala Asn Phe Gln Phe Leu Phe Asn Met

565 570 575Gly Val Arg Met Asn Leu Ala Arg Pro Lys Lys Lys Asp Ser Asp His

580 585 590Ala Ala Gln His Gly Ile Glu Leu Gly Leu Lys Ile Pro Thr Ile Asn

595 600 605Thr Asn Tyr Tyr Ser Phe Met Gly Ala Glu Leu Lys Tyr Arg Arg Leu

610615620 Tyr Ser Val Tyr Leu Asn Tyr Val Phe Ala Tyr 625630635 62560635 (2) SEQ ID NO:1078 message

Sequence properties:

(A) length: 174 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...174

(xi) sequence representation: SEQ ID NO 1078: Ile Lys Arg Ile Ile Lys Ser Asn Ala Ser Leu Asn Gln Leu Asn Thr 151015 Thr Arg Tyr Asn Thr Pro Ser His Leu Phe Phe Lys Lys Gly Val Gly

20 25 30Met Ala Thr Ile Gln Pro Phe Asn His Ser Thr Ile Gln Pro Phe Asn

35 40 45His Ser Thr Ile Gln Pro Phe Asn His Ser Ile Ile Gln Ser Phe Asn

50 55 60His Ser Thr Ile Gln Ala Thr Leu Pro Tyr Phe Tyr Asn Tyr Leu Ser65 70 75 80Phe Tyr Lys Asn Leu Phe Lys Asn Pro Leu Phe Phe Ile Ile Pro Pro

85 90 95Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro

100 105 110Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro

115 120 125Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro Phe Ile Asn Pro

130 135 140Phe Ile Asn Pro Phs Ile Asn Pro Phe Ile Asn Pro Phe Ile Ser Pro145 150 155 160Ser Leu Thr His Ala Thr Thr Phe Ser Asn His Leu Ile Pro

165170 (2) SEQ ID NO 1079 information

Sequence properties:

(A) length: 748 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _feature

(B) Position: 1...748

(xi) sequence representation: SEQ ID NO 1079: Met Glu Asp Phe Leu Tyr Asn Thr Leu Tyr Phe Ile Glu Asp Tyr Lys 151015 Leu Val Val Ile Phe Ser Phe Ile Gly Leu Ile Ala Leu Phe Phe Leu

20 25 30Tyr Lys Phe Ile Lys Thr Gln Lys Lys Val Phe Lys Asp Lys Ala Asn

35 40 45Gln Pro Gln Lys Lys Lys Ser Phe Lys Glu Ile Ile Ile Asp Gly Leu

50 55 60Lys Glu Arg Val Lys Thr Phe Gly Phe Trp Leu Gln Ala Ile Leu Leu65 70 75 80Leu Ser Tyr Ser Phe Ile Thr Ser Gly Leu Phe Phe Leu Ile Leu Leu

85 90 95Gly Asn Phe Tyr Asp Asp Asn Arg Leu Pro Glu Ser Asp Asp Asp Leu

100 105 110Phe Asp Ile Trp Val Tyr Ala Ile Gln Asp Phe Pro Ala Tyr Tyr Phe

115 120 125Lys Ala Leu Thr Phe Ser Ser Leu Lys Ile Tyr Gly Phe Asn Ile Ser

130 135 140Leu Val Val Tyr Ser Ser Ile Leu Cys Ser Tyr Ile Phe Ile Thr Phe145 150 155 160Phe Val Trp Phe Leu Lys Tyr Leu Thr Arg Thr Arg Asp Ile Gly Ala

165 170 175Asn Lys Lys Val Asp Asp Leu Phe Gly Ser Ala Ser Trp Glu Thr Glu

180 185 190Glu Lys Met Ile Lys Ala Lys Leu Ile Thr Pro Asn Asn Lys Lys Arg

195 200 205Ala Phe Asp Lys Arg Glu Val Ile Val Gly Arg Arg Gly Leu Gly Asp

210 215 220Phe Ile Ala Tyr Ala Gly Gln Ala Phe Ile Gly Leu Ile Ala Pro Thr225 230 235 240Arg Ser Gly Lys Gly Val Gly Phe Ile Met Pro Asn Met Ile Asn Tyr

245 250 255Pro Gln Asn Ile Val Val Phe Asp Pro Lys Ala Asp Thr Met Glu Thr

260 265 270Cys Gly Lys Ile Arg Glu Lys Arg Phe Asn Gln Lys Val Phe Ile Tyr

275 280 285Glu Pro Phe Ser Leu Lys Thr His Arg Phe Asn Pro Phe Ala Tyr Val 290 295 300Asp Phe Gly Asn Asp Val Val Leu Thr Glu Asp Ile Leu Ser Gln Ile305 310 315 320Asp Thr Arg Leu Lys Gly His Gly Met Val Ala Ser Gly Gly Asp Phe

325 330 335Ser Thr Gln Ile Phe Gly Leu Ala Lys Leu Val Phe Pro Glu Arg Pro

340 345 350Asn Glu Lys Asp Pro Phe Phe Ser Asn Gln Ala Arg Asn Leu Phe Val

355 360 365Ile Asn Cys Asn Ile Tyr Arg Asp Leu Met Trp Thr Lys Lys Gly Leu

370 375 380Glu Phe Val Lys Arg Lys Lys Ile Ile Met Pro Glu Thr Pro Thr Met385 390 395 400Phe Phe Ile Gly Ser Met Ala Ser Gly Ile Asn Leu Ile Asp Glu Asp

405 410 4l5Thr Asn Met Glu Lys Val Val Ser Leu Met Glu Phe Phe Gly Gly Glu

420 425 430Glu Asp Lys Ser Gly Asp Asn Leu Arg Ala Leu Ser Pro Ala Thr Arg

435 440 445Asn Met Trp Asn Asn Phe Lys Thr Met Gly Gly Ala Lys Glu Thr Tyr

450 455 460Ser Ser Val Gln Gly Val Tyr Thr Ser Ala Phe Ala Pro Tyr Asn Asn465 470 475 480Ala Met Ile Arg Asn Phe Thr Ser Ala Asn Asp Phe Asp Phe Arg Arg

485 490 495Leu Arg Ile Asp Ala Val Ser Ile Gly Val Ile Ala Asn Pro Lys Glu

500 505 510Ser Thr Ile Val Gly Pro Ile Leu Glu Leu Phe Phe Asn Val Met Ile

515 520 525Tyr Ser Asn Leu Ile Leu Pro Ile His Asp Pro Gln Cys Lys Arg Ser

530 535 540Cys Leu Met Leu Met Asp Glu Phe Thr Leu Cys Gly Tyr Leu Glu Thr545 550 555 560Phe Val Lys Ala Val Gly Ile Met Ala Glu Tyr Asn Met Arg Pro Ala

565 570 575Phe Val Phe Gln Ser Lys Ala Gln Leu Glu Asn Asp Pro Pro Leu Gly

580 585 590Tyr Gly Arg Asn Gly Ala Lys Thr Ile Leu Asp Asn Leu Ser Leu Asn

595 600 605Met Tyr Tyr Gly Ile Asn Asn Asp Asn Tyr Tyr Glu Hls Phe Glu Lye

610 615 620Leu Ser Lys Val Leu Gly Lys Tyr Thr Arg Gln Asp Val Ser Arg Ser625 630 635 640Ile Asp Asp Asn Thr Gly Lys Thr Asn Thr Ser Ile Ser Asn Lys Glu

645 650 655Arg Phe Leu Met Thr Pro Asp Glu Leu Met Thr Met Gly Asp Glu Leu

660665 670Ile Ile Leu Glu Asn Thr Leu Lys Pro Ile Lys Cys His Lys Ala Leu

675 680 685Tyr Tyr Asp Asp Pro Phe Phe Thr Asp Glu Leu Ile Lys Val Ser Pro

690 695 700Ser Leu Ser Lys Lys Tyr Lys Leu Gly Lys Val Pro Asn Gln Ala Thr705 710 715 720Phe Tyr Asp Asp Leu Gln Ala Ala Lys Thr Arg Gly Glu Leu Ser Tyr

725 730 735Asp Lys Ser Leu Val Pro Val Gly Ser Ser Glu Leu

740745 (2) SEQ ID NO 1080 information

Sequence properties:

(A) length: 404 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...404

(xi) sequence representation: SEQ ID NO of 1080: Leu Asn Ala Lys Ser Gln Ser Ser Leu Lys Asn Lys Ile Thr Leu Lys 151015 Asn Lys Leu Asn His Ala Arg Ile Ile Leu Glu Phe Ile Pro Ser Leu

20 25 30Ile Tyr Phe Leu Ile Gln Lys Val Ser Val Leu Lys His Leu Ala Pro

35 40 45Leu Ile His Ile Pro Phe Lys Ala Leu Trp Leu Gly Thr Ala Leu Ser

50 5560Met Phe Leu Ser Leu Asn Leu Asn Ala Glu Glu Asn Pro Thr Lys Thr65 70 75 80Glu Pro Lys Pro Ala Lys Gly Val Lys Asn Lys Pro Lys Ser Pro Val

85 90 95Thr Asn Val Met Met Thr Asn Cys Asp Asn Leu Lys Asp Phe Asn Ala

100 105 110Lys Gln Lys Glu Val Leu Lys Ala Ala Tyr Gln Phe Gly Ser Lys Glu

115 120 125Asn Leu Gly Tyr Glu Met Ala Gly Ile Ala Trp Lys Glu Ser Cys Ala

130 135 140Gly Thr Tyr Lys Ile Asn Phe Ser Asp Pro Ser Ala Gly Ile Tyr His145 150 155 160Ala Tyr Ile Pro Ser Val Leu Lys Ser Tyr Gly His Asn Asn Ser Pro

165 170 175Phe Leu Arg Asn Val Met Gly Glu Leu Leu Ile Lys Asp Asp Ala Phe

180 185 190Ala Ser Glu Val Ala Leu Lys Glu Leu Leu Tyr Trp Lys Thr Arg Tyr

195 200 205His Asp Asn Leu Lys Asp Met Ile Lys Ser Tyr Asn Lys Gly Ser Arg

210 215 220Trp Glu Lys Asn Glu Lys Ala Asn Ala Asp Ala Glu Lys Tyr Tyr Glu225 230 235 240Glu Ile Gln Asp Arg Ile Arg Arg Leu Lys Glu Ser Lys Ile Phe Asp

245 250 255Ser Gln Ser Ser Asn Asp Gln Glu Leu Gln Lys Ser Ala Asn Ser Asn

260 265 270Leu Asp Leu Asp Pro Ile Gly Asn Ala Met Pro Gln Thr Leu Ala Gln

275 280285Thr Glu Thr Gln Lys Ser Gln Ile Glu Lys Ser Gln Ile Glu Glu Ala

290 295 300Gln Thr Gln Lys Ser Gln Glu Met Lys Glu Ala Ala Ser Glu Gln Ala305 310 315 320Ile Lys Lys Pro Leu Glu Lys Glu Lys Asp Lys Pro Met Tyr Leu Ala

325 330 335Gln Ile Asn Ser Ala Asp Phe Ala Pro Ala Lys Lys Ser Pro Lys Lys

340 345 350Pro Ala Lys Ala Ser Pro Lys Arg Ser Ser Lys Asn Asn Ile Ser Val

355 360 365Lys Ser Asn Thr Lys Thr Ala Ser Lys Asn Lys Glu Val Cys Lys Asn

370375380 Cys Ser Pro Gly Gln Arg Asn Ala Ile Leu Ala Asn His Ile Thr Leu 385390395400 Met Gln Glu Leu (2) SEQ ID NO 1081 information

Sequence properties:

(A) length: 270 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...270

(xi) sequence representation: SEQ ID NO 1081: Met Lys Lys Phe Val Val Phe Lys Thr Leu Cys Leu Ser Val Val Leu 151015 Gly Asn Ser Leu Val Ala Ala Glu Gly Ser Thr Glu Val Gln Lys Gln

20 25 30Leu Glu Lys Pro Lys Asp Tyr Lys Ala Val Lys Gly Glu Lys Asn Ala

35 40 45Trp Tyr Leu G1y Ile Ser Tyr Gln Val Gly Gln Ala Ser Gln Ser Val

50 55 60Lys Asn Pro Pro Lys Ser Ser Glu Phe Ash Tyr Pro Lys Phe Pro Val65 70 75 80Gly Lys Thr Asp Tyr Leu Ala Val Met Gln Gly Leu Gly Leu Thr Val

85 90 95Gly Tyr Lys Gln Phe Phe Gly Glu Lys Arg Trp Phe Gly Ala Arg Tyr

100 105 110Tyr Gly Phe Met Asp Tyr Gly His Ala Val Phe Gly Ala Asn Ala Leu

115 120 125Thr Ser Asp Asn Gly Gly Val Cys Lys Leu Asn Glu Pro Cys Ala Thr

130 135 140Lys Val Gly Thr Met Gly Asn Leu Ser Asp Met Phe Thr Tyr Gly Val

150 155 160Gly Ile Asp Thr Leu Tyr Asn Val Ile Asn Lys Glu Asp Ala Ser Phe

165 170 175Gly Phe Phe Phe Gly Ala Gln Ile Ala Gly Asn Ser Trp Gly Asn Thr

180 185 190Thr Gly Ala Phe Leu Glu Thr Lys Ser Pro Tyr Lys His Thr Ser Tyr

195 200 205Ser Leu Asp Pro Ala Ile Phe Gln Phe Leu Phe Asn Leu Gly Ile Arg

210 215 220Thr His Ile Gly Gln His Gln Glu Phe Asp Phe Gly Val Lys Ile Pro225 230 235 240Thr Ile Asn Val Tyr Tyr Phe Asn His Gly Asn Leu Ser Phe Thr Tyr

245 250 255Arg Arg Gln Tyr Ser Leu Tyr Val Gly Tyr Arg Tyr Asn Phe

260265270 (2) SEQ ID NO 1082 message

Sequence properties:

(A) length: 252 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(ii) original source:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...252

(xi) sequence representation: SEQ ID NO 1082: Met Lys Pro Tyr Phe Ser Leu Glu Lys Leu Asp Leu Tyr His Gly Asp 151015 Ala Ser Val Leu Glu Thr Phe Glu Lys Gly Phe Tyr Asp Leu Cys Val

20 25 30Thr Ser Pro Pro Tyr Asn Leu Ser Ile Glu Tyr Gln Gly Ser Asn Asp

35 40 45Phe Arg Ala Tyr Asp Asp Tyr Leu Asn Trp Cys Lys Asn Trp Leu Lys

50 55 60Asn Cys Tyr Phe Trp Gly Lys Glu Gln Ala Arg Leu Cys Leu Asn Val65 70 75 80Pro Leu Asp Thr Asn Lys His Gly Lys Gln Ser Leu Gly Ala Asp Ile

85 90 95Thr Ile Val Ala Lys Glu Cys Gly Trp Lys Tyr Gln Asn Thr Ile Ile

100 105 110Trp Asn Glu Ser Asn Ile Ser Arg Arg Thr Ala Trp Gly Ser Trp Leu

115 120 125Gln Ala Ser Ala Pro Tyr Ala Ile Ala Pro Val Glu Leu Ile Val Val

130 135 140Phe Tyr Lys Asn Glu Tyr Lys Arg Lys Lys Gln Thr Ser Thr Met Ser145 150 155 160Arg Glu Glu Phe Leu Leu Tyr Thr Asn Gly Leu Trp Asn Phe Ser Gly

165 170 175Glu Ser Lys Lys Arg Leu Lys His Pro Ala Pro Phe Pro Arg Glu Leu

180 185 190Pro Arg Arg Cys Ile Gln Leu Phe Ser Phe Leu Glu Asp Thr Ile Phe

195 200 205Asp Pro Phe Ser Gly Ser Gly Thr Thr Ile Leu Glu Ala Asn Ala Leu

210 215 220Gly Arg Phe Ser Val Gly Leu Glu Ile Glu Lys Glu Tyr Cys Glu Leu225 230 235 240Ser Lys Lys Arg Ile Leu Glu Ser Leu Ser Leu Val

245620 (2) SEQ ID NO 1083 message

Sequence properties:

(A) length: 925 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...925

(xi) sequence representation: SEQ ID NO 1083: Leu Val Ile Ile Ser Leu Leu Thr Thr Leu Lys Leu Lys Ser Ile Lys 151015 Glu Ile Ser Ile Lys Lys Phe Ile Leu Ser Ser Leu Val Phe Ala Cys

20 25 30Ile Asn Thr Gly Val Glu Ala Leu Glu Asn Asp Gly Ser Lys Pro Asn

35 40 45Asp Leu Ala Ser Pro Lys Glu Thr Pro Lys Glu Ala Gln Lys Asn Glu

50 55 60Ala Gln Asn Glu Thr Ser Gln Ser Asn Gln Thr Pro Lys Glu Met Lys65 70 75 80Val Lys Ser Ile Ser Tyr Val Gly Leu Ser Tyr Met Ser Asp Met Leu

85 90 95Ala Asn Glu Ile Ala Lys Ile Arg Val Gly Asp Met Val Asp Ser Lys

100 105 110Lys Ile Asp Thr Ala Val Leu Ala Leu Phe Asn Gln Gly Tyr Phe Lys

115 120 125Asp Val Tyr Ala Thr Phe Glu Asn Gly Ile Leu Glu Phe His Phe Asp

130 135 140Glu Lys Ala Arg Ile Ala Gly Val Glu Ile Lys Gly Tyr Gly Thr Glu145 150 155 160Lys Glu Lys Asp Gly Leu Lys Ser Gln Met Gly Ile Lys Lys Gly Asp

165 170 175Thr Phe Asp Glu Gln Lys Leu Glu His Ala Lys Thr Ala Leu Lys Thr

180 185 190Ala Leu Glu Gly Gln Gly Tyr Tyr Gly Ser Val Val Glu Val Arg Thr

195 200 205Glu Lys Val Ser Glu Gly Ala Leu Leu Ile Val Phe Asp Val Asn Arg

210 215 220Gly Asp Ser Ile Tyr Ile Lys Gln Ser Ile Tyr Glu Gly Ser Asp Lys225 230 235 240Leu Lys Arg Arg Val Ile Glu Ser Leu Ser Ala Asn Lys Gln Arg Asp

245 250 255Phe Met Gly Trp Met Trp Gly Leu Asn Asp Gly Lys Leu Arg Leu Asp

260 265 270Gln Leu Glu Tyr Asp Ser Leu Arg Ile Gln Asp Val Tyr Met Arg Arg

275 280 285Gly Tyr Leu Asp Ala His Ile Ser Ser Pro Phe Leu Lys Thr Asp Phe

290 295 300Ser Thr His Asp Ala Lys Leu His Tyr Lys Val Lys Glu Gly Ile Gln305 310 315 320Tyr Arg Ile Ser Asp Ile Leu Ile Glu Ile Asp Asn Pro Val Val Pro

325 330 335Leu Lys Thr Leu Glu Lys Ala Leu Lys Val Lys Arg Lys Asp Val Phe

340 345 350Asn Ile Glu His Leu Arg Ala Asp Ala Gln Ile Leu Lys Thr Glu Ile

355 360 365Ala Asp Lys Gly Tyr Ala Phe Ala Val Val Lys Pro Asp Leu Asp Lys 370 375 380Asp Glu Lys Asn Gly Leu Val Lys Val Ile Tyr Arg Ile Glu Val Gly385 390 395 400Asp Met Val His Ile Asn Asp Val Ile Ile Ser Gly Asn Gln Arg Thr

405 410 415Ser Asp Arg Ile Ile Arg Arg Glu Leu Leu Leu Gly Pro Lys Asp Lys

420 425 430Tyr Asn Leu Thr Lys Leu Arg Asn Ser Glu Asn Ser Leu Arg Arg Leu

435 440 445Gly Phe Phe Ser Lys Val Lys Ile Glu Glu Lys Arg Val Asn Ser Ser

450 455 460Leu Met Asp Leu Leu Val Ser Val Glu Glu Gly Arg Thr Gly Gln Leu465 470475 480Gln Phe Gly Leu Gly Tyr Gly Ser Tyr Gly Gly Leu Met Leu Asn Gly

485 490 495Ser Val Ser Glu Arg Asn Leu Phe Gly Thr Gly Gln Ser Met Ser Leu

500 505 510Tyr Ala Asn Ile Ala Thr Gly Gly Gly Arg Ser Tyr Pro Gly Met Pro

515 520 525Lys Gly Ala Gly Arg Met Phe Ala Gly Asn Leu Ser Leu Thr Asn Pro

530 535 540Arg Ile Phe Asp Ser Trp Tyr Ser Ser Thr Ile Asn Leu Tyr Ala Asp545 550 555 560Tyr Arg Ile Ser Tyr Gln Tyr Ile Gln Gln Gly Gly Gly Phe Gly Val

565 570 575Asn Val Gly Arg Met Leu Gly Asn Arg Thr His Val Ser Leu Gly Tyr

580 585 590Asn Leu Asn Val Thr Lys Leu Leu Gly Phe Ser Ser Pro Leu Tyr Asn

595 600 605Arg Tyr Tyr Ser Ser Val Asn Glu Val Ala Ser Pro Arg Gln Cys Ser

610 615 620Thr Pro Ala Ser Val Ile Ile Asn Arg Leu Ser Gly Gly Arg Thr Pro625 630 635 640Leu Val Pro Glu Ser Cys Ser Ser Pro Gly Ala Ile Thr Thr Ser Pro

645 650 655Glu Ile Lys Gly Ile Trp Asp Arg Asp Tyr His Thr Pro Ile Thr Ser

660 665 670Ser Phe Thr Leu Asp Val Ser Tyr Asp Asn Thr Asp Asp Tyr Tyr Phe

675 680 685Pro Arg Asn Gly Val Ile Phe Ser Ser Tyr Ala Thr Met Ser Gly Leu

690695 700Pro Ser Ser Gly Thr Leu Asn Ser Trp Asn Gly Leu Gly Gly Asn Val705 710 715 720Arg Asn Thr Lys Val Tyr Gly Lys Phe Ala Ala Tyr His His Leu Gln

725 730 735

Lys Tyr Leu Leu Ile Asp Leu Ile Ala Arg Phe Lys Thr Gln Gly Gly

740 745 750Tyr Ile Phe Arg Tyr Asn Thr Asp Asp Tyr Leu Pro Leu Asn Ser Thr

755 760 765Phe Tyr Met Gly Gly Val Thr Thr Val Arg Gly Phe Arg Asn Gly Ser

770 775 780Ile Thr Pro Lys Asp Glu Phe Gly Leu Trp Leu Gly Gly Asp Gly Ile785 790 795 800Phe Thr Ala Ser Thr Glu Leu Ser Tyr Gly Val Leu Lys Ala Ala Lys

805 810 815Met Arg Leu Ala Trp Phe Phe Asp Phe Gly Phe Leu Thr Phe Lys Thr

820 825 830Pro Thr Arg Gly Ser Phe Phe Tyr Asn Ala Pro Thr Thr Thr Ala Asn

835 840 845Phe Lys Asp Tyr Gly Val Val Gly Ala Gly Phe Glu Arg Ala Thr Trp 850 855 860Arg Ala Ser Thr Gly Leu Gln Ile Glu Trp Ile Ser Pro Met Gly Pro865 870 875 880Leu Val Leu Ile Phe Pro Ile Ala Phe Phe Asn Gln Trp Gly Asp Gly

885 890 895Asn Gly Lys Lys Cys Lys Gly Leu Cys Phe Asn Pro Asn Met Asn Asp

900 905 910Tyr Thr Gln His Phe Glu Phe Ser Met Gly Thr Arg Phe

915920925 (2) SEQ ID NO 1084 message

Sequence properties:

(A) length: 191 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...191

(xi) sequence representation: SEQ ID NO 1084: Met Lys Gln Leu Phe Leu Ile Ile Gly Ala Pro Gly Ser Gly Lys Thr 151015 Thr Asp Ala Glu Leu Ile Ala Lys Asn Asn Ser Glu Thr Ile Ala His

20 25 30Phe Ser Thr Gly Asp Leu Leu Arg Ala Glu Ser Ala Lys Lys Thr Glu

35 40 45Arg Gly Leu Leu Ile Glu Lys Phe Thr Ser Gln Gly Glu Leu Val Pro

50 55 60Leu Glu Ile Val Val Glu Thr Ile Leu Ser Ala Ile Lys Ser Ser Ser65 70 75 80Lys Gly Ile Ile Leu Ile Asp Gly Tyr Pro Arg Ser Val Glu Gln Met

85 90 95Gln Ala Leu Asp Lys Glu Leu Asn Ala Gln Asn Glu Val Ile Leu Lys

100 105 110Ser Val Ile Glu Val Glu Val Ser Glu Asn Thr Ala Lys Glu Arg Val

115 120 125Leu Gly Arg Ser Arg Gly Ala Asp Asp Asn Glu Arg Val Phe His Asn

130 135 140Arg Met Arg Val Phe Leu Asp Pro Leu Val Glu Ile Gln Asn Phe Tyr145 150 155 160Lys Ala Lys His Leu His Lys Ile Ile Asn Gly Glu Arg Ser Ile Glu

165 170 175Glu Ile Val Asn Glu Met Gln Lys Tyr Ile Leu Ser Phe Ala Asn

180185190 (2) SEQ ID NO 1085 message

Sequence properties:

(A) length: 340 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...340

(xi) sequence representation: SEQ ID NO 1085: Leu Ser Ser Leu Trp Leu Thr Ash Pro Leu Asn Ala His Glu Lys Asn 151015 Gly Ala Phe Val Gly Ile Ser Leu Glu Val Gly Arg Val Asp Gln Lys

20 25 30Thr Asn Ala Tyr Arg Asn Gly Glu Leu Phe Gln Val Pro Phe Gly Asp

35 40 45Val Ser Ala Asn Asp Asp Gly Lys Val Pro Asp Gly Gln Thr Gly Gly 50 55 60Cys Gln Pro Ala Ser Gly Thr Pro Gly Thr Pro Gly Tyr Thr Lys Ala65 70 75 80Asn Cys Val Val Asn Trp Thr Ser Arg Thr Met Leu Ser Thr Asn Lys

85 90 95Asp Ile Pro Gly Arg Asn Gln Pro Met Tyr Gly Leu Gly Val Met Thr

100 105 110Gly Tyr Lys His Phe Val Gly Lys Lys Arg Trp Phe Gly Leu Arg Tyr

115 120 125Tyr Gly Phe Phe Asp Tyr Gly His Thr Asn Phe Ser Asn Ser Arg Ala

130 135 140Ala Asn Ala Ile Ser Pro Phe Tyr Leu Ser Asp Gln Lys Ala Asp Met145 150 155 160Tyr Thr Tyr Gly Phe Gly Thr Asp Met Leu Phe Asn Val Ile Asp Lys

165 170 175Pro Lys Ala Thr Ala Gly Phe Phe Val Gly Val Asn Phe Ala Gly Asn

180 185 190Thr Trp Thr Asn Asn Arg Val Gly Tyr Phe Lys Asp Gly Tyr Val Tyr

195 200 205Gly Val Asn Thr Asp Ala Asp Ala Tyr Met Thr Asn Ala Asp Gly Thr

210 215 220Ile Thr Cys Gly Asp Thr Thr Pro Ala Ser Cys Asn Val Gly Ile Asn225 230 235 240Pro Asn Ser Val Tyr Thr Thr Gly Lys Leu Asn Ala Lys Val Asn His

245 250 255Thr Ile Phe Gln Phe Leu Val Asn Val Gly Ile Arg Thr Asn Ile Phe

260 265 270Glu His His Gly Ile Glu Phe Gly Ile Lys Ile Pro Thr Leu Pro Asn

275 280 285Tyr Phe Phe Lys Gly Ser Thr Thr Ile Arg Ala Lys Lys Gln Gly Pro

290 295 300Leu Glu Asn Gly Asn Pro Thr Thr Ile Thr Gly Ala Glu Thr Asn Phe305 310 315 320Ser Leu Thr Gln Thr Leu Arg Arg Gln TyrSer Met Tyr Leu Arg Tyr

325 330 335Val Tyr Thr Phe

340(2) SEQ ID NO 1086 message

Sequence properties:

(A) length: 528 amino acid residue

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...528

(xi) sequence representation: SEQ ID NO 1086: Met Lys Leu Lys Lys Arg Lys Val Ala Ala Thr Leu Leu Lys Arg Leu 151015 Thr Leu Pro Leu Leu Phe Thr Thr Gly Ser Leu Gly Ala Val Thr Tyr

20 25 30Glu Val His Gly Asp Phe Ile Asn Phe Ser Lys Val Gly Phe Asn Arg

35 40 45Ser Pro Ile Asn Pro Val Lys Gly Ile Tyr Pro Thr Glu Thr Phe Val

50 55 60Ash Leu Thr Gly Lys Leu Glu Gly Ser Val His Leu Gly Arg Gly Trp65 70 75 80Thr Val Asn Val Gly Gly Val Leu Gly Gly Gln Val Tyr Asp Asn Thr

85 90 95Arg Tyr Asp Arg Trp Ala Lys Asp Phe Thr Pro Pro Ser Tyr Trp Asp

100 105 l10Lys Thr Ser Cys Gly Thr Asp Ser Leu Ser Leu Cys Met Asn Ala Thr

115 120 125Lys Met Trp Gln Gln Gln Gly Pro Gly Gly Ile Ile Asp Pro Arg Gly 130 135 140Ile Gly Tyr Met Tyr Met Gly Glu Trp Asn Gly Leu Phe Pro Asn Tyr145 150 155 160Tyr Pro Ala Asn Ala Tyr Leu Pro Gly His Ser Arg Arg Tyr Glu Val

165 170 175

Tyr Lys Ala Asn Leu Thr Tyr Asp Ser Asp Arg Val His Met Val Met

180 185 190Gly Arg Phe Asp Val Thr Glu Gln Glu Gln Met Asp Trp Ile Tyr Gln

195 200 205Leu Phe Gln Gly Phe Tyr Gly Thr Phe Lys Leu Thr Lys Asn Met Lys

210 215 220Phe Leu Leu Phe Ser Ser Trp Gly Arg Gly Ile Ala Asp Gly Gln Trp225 230 235 240Leu Phe Pro Ile Tyr Arg Glu Lys Pro Trp Gly Ile His Lys Ala Gly

245 250 255Ile Ile Tyr Arg Pro Thr Lys Asn Leu Met Ile His Pro Tyr Val Tyr

260 265 270Leu Ile Pro Met Val Gly Thr Leu Pro Gly Ala Lys Ile Glu Tyr Asp

275 280 285Thr Asn Pro Glu Phe Ser Gly Arg Gly Ile Arg Asn Lys Thr Thr Phe

290 295 300Tyr Val teu Tyr Asp Tyr Arg Trp Asn Asn Ala Glu Tyr Gly Arg Tyr305 310 315 320Ala Pro Ala Arg Tyr Asn Thr Trp Asp Pro Phe Leu Asp Asn Gly Lys

325 330 335Trp Arg Gly Leu Gln Gly Pro Gly Gly Ala Thr Leu Tyr Leu His His

340 345 350His Ile Asp Ile Asn Asn Tyr Phe Val Val Gly Gly Ala Tyr Leu Asn

355 360 365Ile Gly Asn Pro Asn Met Asn Leu Gly Thr Trp Gly Asn Pro Val Ala

370 375 380Leu Asp Gly Ile Glu Gln Trp Val Gly Gly Ile Tyr Ser Leu Gly Phe385 390 395 400Ala Gly Ile Asp Asn Ile Thr Asp Ala Asp Ala Phe Thr Glu Tyr Val

405 410 415Lys Gly Gly Gly Lys His Gly Lys Phe Ser Trp Ser Val Tyr Gln Arg

420 425 430Phe Thr Thr Ala Pro Arg Ala Leu Glu Tyr Gly Ile Gly Met Tyr Leu

435 440 445Asp Tyr Gln Phe Ser Lys His Val Lys Ala Gly Leu Lys Leu Val Trp

450 455 460Leu Glu Phe Gln Ile Arg Ala Gly Tyr Asn Pro Gly Thr Gly Phe Leu465 470 475 480Gly Pro Asn Gly Gln Pro Leu Asn Leu Asn Asn Gly Leu Phe Glu Ser

485 490 495Ser Ala Phe Ala Gln Gly Pro Gln Asn Met Gly Gly Ile Ala Lys Ser

500 505 510Ile Thr Gln Asp Arg Ser His Leu Met Thr His Ile Ser Tyr Ser Phe

515520525 (2) information SEQ ID NO 1087

Sequence properties:

(A) length: 234 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...234

(xi) sequence representation: SEQ ID NO 1087: Met Thr Lys Ile Ala Met Ala Asn Phe Lys Ser Ala Met Pro Val Phe 151015 Lys Ser His Ala Tyr Leu Lys Glu Leu Glu Lys Thr Leu Lys Pro Gln

20 25 30His Phe Asp Arg Val Phe Val Phe Pro Asp Phe Leu Gly Leu Leu Pro

35 40 45Asn Ala Phe Leu His Phe Thr Leu Gly Ala Gln Asn Ala Tyr Pro Arg

50 55 60Asp Cys Gly Ala Phe Thr Gly Glu Ile Thr Ser Lys His Leu Glu Glu65 70 75 80Leu Lys Ile His Thr Leu Leu Ile Gly His Ser Glu Arg Arg Val Leu

85 90 95Leu Lys Glu Ser Pro Ser Phe Leu Lys Glu Lys Phe Asp Phe Phe Lys

100 105 110Gly Lys Asn Phe Lys Ile Val Tyr Cys Ile Gly Glu Asp Leu Thr Thr

115 120 125Arg Glu Lys Gly Phe Arg Ala Val Lys Glu Phe Leu Ser Glu Gln Leu

130 135 140Glu Asn Ile Asp Leu Asn Tyr Ser Asn Leu Ile Val Ala Tyr Glu Pro145 150 155 160Ile Trp Ala Ile Gly Thr Lys Lys Ser Ala Ser Leu Glu Asp Ile Tyr

165 170 175Leu Thr His Gly Phe Leu Lys Gln Ile Leu Asn Gln Lys Thr Pro Leu

180 185 190Leu Tyr Gly Gly Ser Val Asn Ala Gln Asn Ala Lys Glu Ile Leu Gly

195 200 205Ile Asp Ser Val Asp Gly Leu Leu Ile Gly Ser Ala Ser Leu Glu Leu

210215220 Glu Asn Phe Lys Thr Ile Ile Ser Phe Leu 225230 (2) SEQ ID NO:1088 information

Sequence properties:

(A) length: 465 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...465

(xi) sequence representation: SEQ ID NO 1088: Met Phe Ile Tyr Asp Thr Lys Leu Lys Gln Lys Val Pro Phe Glu Pro 151015 Leu Val His Asn Lys Ala Asn Ile Tyr Val Cys Gly Pro Thr Val Tyr

20 25 30Asp Asp Ala His Leu Gly His Ala Arg Ser Ala Ile Ala Phe Asp Leu

35 40 45Leu Arg Arg Thr Leu Glu Leu Ser Gly Tyr Glu Val Val Leu Val Arg

50 55 60Asn Phe Thr Asp Ile Asp Asp Lys Ile Ile Asn Lys Ala Phe Lys Glu65 70 75 80Asn Lys Ser Ile Gln Glu Leu Ser Ser Ile Tyr Ile Glu Ser Tyr Thr

85 90 95Arg Asp Leu Asn Ala Leu Asn Val Lys Gln Pro Ser Leu Glu Pro Lys

100 105 110Ala Ser Glu Tyr Leu Asp Ala Met Val Arg Met Ile Glu Thr Leu Leu

115 120 125Glu Lys Asn Phe Ala Tyr Arg Val Ser Asn Gly Asp Ile Tyr Leu Asp

130 135 140Thr Ser Lys Asp Lys Asp Tyr Gly Ser Leu Ser Met His Ash Ser Ser145 150 155 160Val Glu Phe Ser Arg Ile Gly Leu Val Gln Glu Lys Arg Leu Glu Gln

165 170 175Asp Phe Val Leu Trp Lys Ser Tyr Lys Gly Asp Asn Asp Val Gly Phe

180 185 190Asp Ser Pro Leu Gly Lys Gly Arg Pro Gly Trp His Ile Glu Cys Ser

195 200 205Ser Met Val Phe Glu Thr Leu Ala Leu Ala Asn Ala Pro Tyr Gln Ile

210 215 220Asp Ile His Ala Gly Gly Thr Asp Leu Leu Phe Pro His His Glu Asn225 230 235 240Glu Ala Cys Gln Thr Arg Cys Ala Phe Gly Val Glu Ile Ala Lys Tyr

245 250 255Trp Met His Asn Gly Phe Val Asn Ile Asn Asn Glu Lys Met Ser Lys

260 265 270Ser Leu Gly Asn Ser Phe Phe Ile Lys Asp Ala Leu Lys Asn Tyr Asp

275 280 285Gly Glu Ile Leu Arg Asn Tyr Leu Leu Gly Val His Tyr Arg Ser Val

290 295 300Leu Asn Phe Asn Glu Glu Asp Leu Leu Met Ser Lys Lys Arg Leu Asp305 310 315 320Lys Ile Tyr Arg Leu Lys Gln Arg Val Leu Gly Thr Leu Gly Gly Ile

325 330 335Asn Pro Asn Phe Lys Lys Glu Ile Leu Glu Cys Met Gln Asp Asp Leu

340 345 350Asn Val Ser Lys Ala Leu Ser Val Leu Glu Ser Met Leu Ser Ser Thr

355 360 365Asn Glu Lys Leu Asp Gln Asn Pro Lys Asn Lys Ala Leu Lys Gly Glu

370 375 380Ile Leu Ala Asn Leu Lys Phe Ile Glu Glu Leu Leu Gly Ile Gly Phe385 390 395 400Lys Asp Pro Ser Ala Tyr Phe Gln Leu Gly Val Ser Glu Ser Glu Lys

405 410 415Gln Glu Ile Glu Asn Lys Ile Glu Glu Arg Lys Arg Ala Lys Glu Gln

420 425 430Lys Asp Phe Leu Lys Ala Asp Ser Ile Arg Glu Glu Leu Leu Gln Gln

435 440 445Lys Ile Ala Leu Met Asp Thr Pro Gln Gly Thr Ils Trp Glu Lys Leu

450455460 Phe465(2) SEQ ID NO:1089 information

Sequence properties:

(A) length: 1213 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1213

(xi) sequence representation: SEQ ID NO 1089: Met Lys Gln Phe Lys Lys Lys Pro Lys Lys Ile Lys Arg Ser His Gln 151015 Asn Gln Lys Thr Ile Leu Lys Arg Pro Leu Trp Leu Met Pro Leu Leu

20 25 30Ile Gly Gly Phe Ala Ser Gly Val Tyr Ala Asp Gly Thr Asp Ile Leu

35 40 45Gly Leu Ser Trp Gly Glu Lys Ser Gln Lys Val Cys Val His Arg Pro

50 55 60Trp Tyr Ala Ile Trp Ser Cys Asp Lys Trp Glu Glu Lys Thr Gln Gln65 70 75 80Phe Thr Gly Asn Gln Leu Ile Thr Lys Thr Trp Ala Gly Gly Asn Ala

85 90 95Ala Asn Tyr Tyr His Ser Gln Asn Asn Gln Asp Ile Thr Ala Asn Leu

100 105 110Lys Asn Asp Asn Gly Thr Tyr Phe Leu Ser Gly Leu Tyr Asn Tyr Thr

115 120 125Gly Gly Glu Tyr Asn Gly Gly Asn Leu Asp Ile Glu Leu Gly Ser Asn

130 135 140Ala Thr Phe Asn Leu Gly Ala Ser Ser Gly Asn Ser Phe Thr Ser Trp145 150 155 160Tyr Pro Asn Gly His Thr Asp Val Thr Phe Ser Ala Gly Thr Ile Asn

165 170 175Val Asn Asn Ser Val Glu Val Gly Asn Arg Val Gly Ser Gly Ala Gly

180 185 190Thr His Thr Gly Thr Ala Thr Leu Asn Leu Asn Ala Asn Lys Val Thr

195 200 205Ile Asn Ser Asn Ile Ser Ala Tyr Lys Thr Ser Gln Val Asn Val Gly

210 215 220Asn Ala Asn Ser ValIle Thr Ile Asn Ser Val Ser Leu Asn Gly Asp225 230 235 240Thr Cys Ser Ser Leu Ala Arg Val Gly Val Gly Ala Asn Cys Ser Thr

245 250 255Ser Gly Pro Ser Tyr Ser Phe Lys Gly Thr Thr Asn Ala Thr Asn Thr

260 265 270Thr Phe Ser Asn Ser Ser Gly Ser Phe Thr Phe Glu Glu Asn Ala Thr

275 280 285Phe Ser Gly Ala Lys Leu Asn Gly Gly Ala Phe Thr Phe Asn Lys Lys

290 295 300Phe Asn Ala Thr Asn Asn Thr Ala Phe Asn Ser Gly Ser Phe Thr Phe305 310 315 320Lys Gly Thr Ser Ser Phe Asn Gly Ala Asn Phe Ser Asn Ala Ser Tyr

325 330 335Thr Phe Asn Asn Gln Ala Thr Phe Gln Asn Ser Ser Phe Asn Gly Gly

340 345 350Thr Phe Thr Phe Asn Asp Gln Thr Asn Gln Ser Thr Gln His Pro Gln

355 360 365Ile Gln Asn Ser Ser Phe Ser Gly Ser Ala Thr Thr Leu Lys Gly Phe

370 375 380Ala Thr Phe Glu Gln Ala Phe Asn Asn Ser Asn His Gln Leu Thr Ile385 390 395 400Gln Ash Ala Ser Phe Asn Asn Ala Thr Phe Asn Asn Thr Gly Lys Ile

405 410 415Thr Ile Glu Lys Asp Ala Ser Phe Asn Asn Thr Ser Phe Asn Thr Pro

420 425 430Val Asp Thr Asn Asn Met Thr Ile Ser Gly Gly Val Thr Leu Ser Gly

435 440 445Lys AsnAsp Leu Lys Asn Gly Ala Thr Leu Asp Phe Gly Ser Ser Lys

450 455 460Ile Thr Leu Thr Gln Gly Thr Thr Phe Asn Leu Thr Ser Leu Gly Ser465 470 475 480Glu Lys Ser Val Thr Ile Leu Asn Ser Arg Gly Gly Ile Thr Tyr Asn

485 490 495His Leu Leu Asn His Ala Ile Asn Ser Leu Thr Asn Ala Leu Lys Thr

500 505 510Asn Glu Ser Ser Ser Lys Pro Gln Ser Phe Ala Gln Gly Leu Trp Asp

515 520 525Met Ile Thr Tyr Asn Gly Val Thr Gly Gln Leu Leu Asn Glu Asn Ala

530 535 540Ala Thr Ser Lys Pro Thr Asp Ser Ser Pro Ser Lys Ser Ser Thr Asn545 550 555 560Ser Thr Gln Val Tyr Gln Val Gly Tyr Lys Ile Gly Asp Thr Ile Tyr

565 570 575Lys Leu Gln Glu Thr Phe Ser His Asn Ser Ile Ile Ile Gln Ala Leu

580 585 590Glu Ser Gly Thr Tyr Thr Pro Pro Pro Val Ile Asn Gly Ser Lys Phe

595 600 605Asp Leu Ser Ala Ser Asn Tyr Ile Asn Ala Asp Met Pro Trp Tyr Asn

610 615 620His Lys Tyr Tyr Ile Pro Lys Ser Gln Asn Phe Thr Glu Ser Gly Thr625 630 635 640Tyr Tyr Leu Pro Ser Val Gln Ile Trp Gly Ser Tyr Thr Asn Ser Phe

645 650 655Lys Gln Thr Phe Ser Ala Ser Asn Ser Asn Leu Val Ile Gly Tyr Asn

660 665 670Ala Thr Trp Thr Asp His Asn Val Ser Ser Ser Asp Thr Val Ala Phe

675 680 685Gly Asp Thr Ser Gly Ser Ala Leu Asn Gly His Cys Gly Pro Trp Pro

690 695 700Tyr Tyr Glp Cys Thr Gly Thr Thr Asn Gly Thr Tyr Ser Ala Tyr His705 710 715 720Val Tyr Ile Thr Ala Asn Leu Arg Ser Gly Asn Arg Ile Gly Thr Gly

725 730 735Gly Ala Ala Asn Leu Ile Phe Asn Gly Val Asp Ser Ile Asn Ile Ala

740 745 750Asn Ala Thr Ile Thr Gln His Asn Ala Gly Ala Tyr Ser Ser Ser Met

755 760 765Thr Phe Ser Thr Gln Asn Met Asp Asn Ser Gln Asn Leu Asn Gly Leu

770 775 780Asn Ser Asn Gly Lys Leu Leu Val Tyr Gly Thr Thr Phe Thr Asn Gln785 790 795 800Ala Lys Asp G1y Lys Phe Ile Phe Asn Ala Gly Gln Ala Thr Phe Glu

805 810 815Asn Thr Asn Phe Asn Gly Gly Ser Tyr Gln Phe Ser Gly Asp Ser Leu

820 825 830Asn Phe Ser Asn Asn Asn Gln Phe Asn Ser Gly Ser Phe Glu Ile Gly

835 840 845Ala Lys Asn Thr Ile Phe Asn Asn Ala Asn Phe Asn Asn Ser Thr Ser

850 855 860Phe Asn Phe Asn Asn Ser Ser Ala Thr Thr Ser Phe Val Gly Asp Phe865 870 875 880Thr Asn Ala Asn Ser Asn Leu Gln Ile Ala Gly Asn Ala Val Phe Gly

885 890 895Asn Ser Thr Asn Gly Ser Gln Asn Thr Ala Asn Phe Asn Asn Thr Gly

900 905 910Ser Val Asn Ile Ala Gly Asn Ala Thr Phe Asp Asn Val Val Phe Asn

915 920 925Ser Pro Thr Asn Thr Ser Val Lys Gly Lys Val Thr Leu Asn Asn Ile

930 935 940Thr Leu Lys Asn Leu Asn Ala Pro Leu Ser Phe Gly Asp Gly Thr Ile945 950 955 960Val Phe Ser Ala His Ser Val Ile Asn Ile Gly Glu Ala Ile Thr Asn

965 970 975Gly Asn Pro Ile Thr Leu Val Ser Ser Ser Lys Ala Ile Glu Tyr Asn

980 985 990Asp Ala Phe Ser Lys Asn Leu Trp Gln Leu Ile Asn Tyr Gln Gly His

995 1000 1005Gly Ala Ser Ser Glu Lys Leu Val Ser Ser Ala Gly Asn Gly Val Tyr

1010 1015 1020Asp Val Val Tyr Ser Phe Asn Asn Gln Thr Tyr Asn Phe Gln Glu Val1025 1030 1035 1040Phe Ser Pro Asn Ser Ile Ser Ile Arg Arg Leu Gly Val Gly Met Val

1045 1050 1055Phe Asp Tyr Val Asp Met Glu Lys Ser Asp Arg Leu Tyr Tyr Gln Asn

1060 1065 1070Ala Leu Gly Phe Met Thr Tyr Met Pro Asn Ser Tyr Asn Asn Asn Leu

1075 1080 1085Gly Asn Leu Asn Asn Thr Ile Tyr Tyr Tyr Asp Asn Ser Ile Asp Phe 1090 1095 1100Tyr Ala Ser Gly Lys Thr Leu Phe Thr Lys Ala Glu Phe Ser Gln Thr1105 1110 1115 1120Phe Thr Gly Gln Asn Ser Ala Ile Val Phe Gly Ala Lys Asn Ile Trp

1125 1130 1135Thr Ser Val Ser Asp Ala Pro Gln Ser Asn Val Ile Ile Arg Phe Gly

1140 1145 1150Asp Asn Lys Gly Ala Gly Ser Asn Asp Ala Ser Gly His Cys Trp Asn

1155 1160 1165Leu Gln Cys Ile Gly Phe Ile Thr Gly His Tyr Glu Ala Gln Lys Ile

1170 1175 1180Tyr Ile Thr Gly Ser Ile Glu Ser Gly Asn Arg Ile Ser Ser Gly Gly1185 1190 1195 1200Ala Arg Ala Leu Ile Leu Thr Gly Phe Lys Ala Phe Phe

12051210 (2) SEQ ID NO 1090 information

Sequence properties:

(A) length: 500 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...500

(xi) sequence representation: 1090: Met Ala Glu Trp Lys Thr Asp Thr Glu Glu Val Lys Lys Val Val Gly 151015 Arg Cys Arg Glu Phe Lys Arg Ser Leu Gln Glu Glu Lys Cys Ser Pro SEQ ID NO

20 25 30Phe Ile Lys Asp Leu Asp Ser Tyr Ala Leu Lys Ile Ile Val Glu Arg

35 40 45Arg Lys Thr Glu Met Gln Leu Glu Lys Ala Ile Gly Glu Leu Lys Lys

50 55 60Ala Lys Ser Asn Glu Asp Asp Ala Lys Val Ala Leu Arg Val Leu Gln65 70 75 80Gly Ala Ser Val Val Ser Trp Ile Trp Pro Pro Ala Arg Ile Ala Ala

85 90 95Thr Ala Ala Ile Val Ala Ala Glu Ala Val Leu Lys Phe Met Lys Glu

100 105 110Asp Thr Glu Lys Cys Lys Arg Asn Val Glu Leu Leu Glu Arg Met Leu

115 120 125Glu Ile Tyr Ser Asn Gln Ala Lys Ala Ser Ala Asn Leu Met Asn Gln

130 135 140Ala Trp Glu Gly Ile Lys Lys Arg Leu His Phe Tyr Thr Asp Lys His145 150 155 160Gln Glu Phe Ile Arg Arg Leu Lys Gln Ala Ser Asp Ala Ile Asp Asn

165 170 175Glu Tyr Asn Phe Pro Thr Pro Gly Val Leu Leu Glu Tyr Asp Phe Glu

180 185 190Arg Pro Ala Ile Ser Tyr Thr Pro Lys Lys Ser Val Phe Asn Glu Arg

195 200 205

Leu Lys Asp Leu Arg Glu Asn Phe Ser Ala Ser Leu Tyr Ala Asp Leu

210 215 220Lys Asp Lys Ile His His Asn Ala Leu Ser Asn Asp Asp Leu Glu Arg225 230 235 240Met Ile Ala Phe Arg Glu Gln Glu Phe Glu Lys Ser Leu Glu Asp Trp

245 250 255Met Gly Ala Tyr Ser Tyr Asp Glu Asn Pro Asn Asp Glu Leu Asp Arg

260265 270Met Ala Ile Ser Lys Glu Gln Glu Leu Glu Lys Ser Leu Glu Asp Leu

275 280 285Met Pro Ser Val Leu Gly Val Pro Ser Tyr Asn Glu Ser Leu Thr Leu

290 295 300Ala Lys Asn Arg Cys Val Lys Asn Phe Lys Glu Ala Leu Glu Gly Phe305 310 315 320Thr Glu Lys Ile Lys Glu Ser Pro Asn Asp Ser Asn Ala Ile Asn Glu

325 330 335Ala Phe Asp Asn Leu Glu Thr Glu Leu Glu Arg Ala Thr Glu Asn Leu

340 345 350Ser Gln Lys Ile Asp Pro Val Leu Glu Arg Asn Glu Asn Tyr Thr Gln

355 360 365Lys Ala Leu Glu Tyr Arg Glu Phe Leu Glu Ser Arg Lys Glu Ser Phe

370 375 380Ile Val Asp Glu Lys Asn Pro Tyr Pro Glu Glu Val Ser Phe Asn Glu385 390 395 400Trp Arg Trp Ala Glu Phe Asp Ser Val Phe Ser Ala Ile Val Pro Leu

405 410 415Glu Asp Leu Asn Lys Thr Ala Cys Ala His His Ala Leu Lys Ala Leu

420 425 430Gln Ala Thr Leu Lys Asp Asn Asp Leu Gly Phe Asp Ala Thr Glu Leu

435 440 445Glu Gln Ile Ala Lys Gly Phe Ile Pro Arg Gly Tyr Leu Trp His Phe

450 455 460Asp Ala Asn Val Leu Gly Asn Leu Ala Leu Val Arg Glu Glu Leu Leu465 470 475 480Leu Gly Val Lys His Thr Lys Gly Tyr Ser Leu Trp Thr Glu Phe Leu

485 490495Gln Lys Gln Asn

500(2) SEQ ID NO 1091 message

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(vi) antisense strand: is free of

(ix) original source:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1091: TTAACCATGG TGAAAAGCGA TA 22(2) SEQ ID NO 1092 information

Sequence properties:

(A) length: 23 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...23

(xi) sequence representation: 1092: TAGAATTCGC ATAACGATCA ATC 23(2) SEQ ID NO 1093 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: 1093: TTAACCATGG TGAAAAGCGA TA 22(2) SEQ ID NO 1094 information

Sequence properties:

(A) length: 23 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...23

(xi) sequence representation: SEQ ID NO 1094: TAGAATTCGC ATAACGATCA ATC 23(2) SEQ ID NO 1095 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: 1095: ATATCCATGG TGAGTTTGAT GA 22(2) SEQ ID NO 1096 information

Sequence properties:

(A) length: 25 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...25

(xi) sequence representation: 1096: ATGAATTCAA TTTTTTATTT TGCCA 25(2) SEQ ID NO 1097 information

Sequence properties:

(A) length: 23 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...23

(xi) sequence representation: 1097: AATTCCATGG CTATCCAAAT CCG 23(2) SEQ ID NO 1098 information

Sequence properties:

(A) length: 25 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...25

(xi) sequence representation: 1098: ATGAATTCGC CAAAATCGTA GTATT 25(2) SEQ ID NO 1099 information

Sequence properties:

(A) length: 24 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...24

(xi) sequence representation: 1099: GATACCATGG AATTTATGAA AAAG 24(2) SEQ ID NO 1100 message

Sequence properties:

(A) length: 25 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...25

(xi) sequence representation: SEQ ID NO 1100: TGAATTCGAA AAAGTGTAGT TATAC 25(2) SEQ ID NO 1101 information

Sequence properties:

(A) length: 19 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...19

(xi) sequence representation: SEQ ID NO 1101: CCCTTCATTT TAGAAATCG 19(2) SEQ ID NO 1102 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1102: ATTTCAACCA ATTCAATGCG 20(2) SEQ ID NO 1103 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1103: GCCCCTTTTG ATTTGAAGCT 20(2) SEQ ID NO 1104 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1104: TCGCTCCAAG ATACCAAGAA GT 22(2) SEQ ID NO 1105 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1105: CTTGAATTAG GGGCAAAGAT CG 22(2) SEQ ID NO 1106 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1106: ATGCGTTTTT ACCCAAAGAA GT 22(2) SEQ ID NO 1107 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO:1107: ATAACGCCAC TTCCTTATTG GT 22(2) SEQ ID NO:1108 information

Sequence properties:

(A) length: 19 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(ii) original source:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...19

(xi) sequence representation: SEQ ID NO 1108: CTTTGGGTAA AAACGCATC 19(2) SEQ ID NO 1109 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1109: CGATCTTTGA TCCTAATTCA 20(2) SEQ ID NO 1110 information

Sequence properties:

(A) length: 19 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...19

(xi) sequence representation: SEQ ID NO 1110: ATCAAGTTGC CTATGCTGA 19(2) SEQ ID NO 1111 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii)assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: 1111: TTGAACACTT TTGATTATGC GG 22(2) SEQ ID NO 1112 information

Sequence properties:

(A) length: 23 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...23

(xi) sequence representation: SEQ ID NO 1112: GGATTATGCG ATTGTTTTAC AAG 23(2) SEQ ID NO 1113 message

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv)antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1113: GTCTTTAGCA AAAATGGCGT C21 (2) SEQ ID NO 1114 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1114: AATGAGCGTA AGAGAGCCTT C21 (2) SEQ ID NO 1115 information

Sequence properties:

(A) length: 18 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...18

(xi) sequence representation: 1115 to CTTATGGGGG TATTGTCA 18(2) SEQ ID NO 1116 information

Sequence properties:

(A) length: 18 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...18

(xi) sequence representation: SEQ ID NO 1116: AGCATGTGGG TATCCAGC 18(2) information SEQ ID NO 1117

Sequence properties:

(A) length: 19 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...19

(xi) sequence representation: SEQ ID NO 1117 AGGTTGTTGC CTAAAGACT 19(2) SEQ ID NO 1118 information

Sequence properties:

(A) length: 18 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...18

(xi) sequence representation: SEQ ID NO 1118: CTGCCTCCAC CTTTGATC 18(2) SEQ ID NO 1119 information

Sequence properties:

(A) length: 19 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...19

(xi) sequence representation: SEQ ID NO 1119: ACCAATATCA ATTGGCACT 19(2) SEQ ID NO 1120 information

Sequence properties:

(A) length: 18 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...18

(xi) sequence representation: SEQ ID NO 1120: ACTTGGAAAA GCTCTGCA 18(2) SEQ ID NO 1121 information

Sequence properties:

(A) length: 19 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...19

(xi) sequence representation: 1121: CTTGCTTGTC ATATCTAGC 19(2) SEQ ID NO 1122 information

Sequence properties:

(A) length: 18 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...18

(xi) sequence representation: SEQ ID NO 1122: GTTGAAGTGT TGGTGCTA 18(2) information SEQ ID NO 1123

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1123: CAAGCAAGTG GTTTGGTTTT AG 22(2) SEQ ID NO 1124 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1124: TGGAAAGAGC AAATCATTGA AG 22(2) SEQ ID NO 1125 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: 1125: GCCCATAATC AAAAAGCCCA T21 (2) SEQ ID NO 1126 information

Sequence properties:

(A) length: 24 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...24

(xi) sequence representation: SEQ ID NO 1126: CTAAAACCAA ACCACTTGCT TGTC 24(2) SEQ ID NO 1127 information

Sequence properties:

(A) length: 16 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...16

(xi) sequence representation: 1127: GTAAAACGAC GGCCAG 16(2) SEQ ID NO 1128 information

Sequence properties:

(A) length: 17 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...17

(xi) sequence representation: 1128: CAGGAAACAG CTATGAC 17(2) SEQ ID NO 1129 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1129: TTGCCCCATC GTATTGATAG A21 (2) SEQ ID NO 1130 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: 1130: AGAGCGTATT TCACCCGAAA G21 (2) SEQ ID NO 1131 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1131: TCTTGCATCT TAATCCACTC C21 (2) SEQ ID NO 1132 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: 1132, CGGGTCAAAACGACCACTTA A21, (2) SEQ ID NO 1133 messages

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1133: AATCCGTTTC GCTAATTTAGT 21(2) SEQ ID NO 1134 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1134: AACACTTCAA TTTCCTCTAT A21 (2) SEQ ID NO 1135 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1135: TGGTATAAGG ATTTGAATGG A21 (2) SEQ ID NO 1136 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1136: TTGACTAAAC ACATGCGAGA A21 (2) SEQ ID NO 1137 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1137: ATAGAGAGCG TTGTGTTTAG C21 (2) SEQ ID NO 1138 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1138: CCTTTATTGG TTTTGATCGT G21 (2) SEQ ID NO 1139 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1139: ATGTCCGTTG TCTGTATGGA A21 (2) SEQ ID NO 1140 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1140, TAGGGTGTCT AGGGATTTGA T21 (2) SEQ ID NO 1141 message

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1141: GCGTTTGGCT TCTTCGTTGT C21 (2) SEQ ID NO 1142 message

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1142 GAAATGGAAA ATAGCGGTCA A21 (2) SEQ ID NO 1143 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1143 GCAAATCCCC AGCCACTTCC 20(2) SEQ ID NO 1144 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1144: GTGGCTAAAA ATGAGGGCTT 20(2) SEQ ID NO 1145 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1145: GTTAGGAAAT TAGAAATCAT TG 22(2) SEQ ID NO 1146 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1146 GCTAAAACTT CATCGCTCAA T21 (2) SEQ ID NO 1147 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1147 GTTGGGCAGA AAATAAGCTG A21 (2) SEQ ID NO 1148 message

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1148 CAAACAAACC TGACAAGAAA C21 (2) SEQ ID NO 1149 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1149: CATTGATGCC TAAAACTTCG 20(2) SEQ ID NO 1150 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1150: CGTGGTGGTT TTCCCGTTAG 20(2) SEQ ID NO 1151 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: 1151: GGGGCATTGT GTTTGTTTTT 20(2) SEQ ID NO 1152 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1152: TGGTCTATCA TGCGAATTAT 20(2) SEQ ID NO 1153 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1153: GCCCTGATCC ATTCCCCCCT 20(2) SEQ ID NO 1154 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1154: CGCGCTAGAG GCTTGTAAAA 20(2) SEQ ID NO 1155 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: 1155: GCCCTGATCC ATTCCCCCCT 20(2) SEQ ID NO 1156 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1156: CTGTTTTTAG CGTCCCTGTA 20(2) SEQ ID NO 1157 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: 1157: GGCGTTATTA AGCGACATCG 20(2) SEQ ID NO 1158 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: 1158: TTTCACCGGC AATTTTAGGC 20(2) SEQ ID NO 1159 message

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1159: GCGTTTTGAT TCTGTCTGTT A21 (2) SEQ ID NO 1160 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1160: GTAAAAACAC CGCTAACGCA T21 (2) SEQ ID NO 1161 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1161: GCGTGTTTTC TAAGGGTTCA 20(2) SEQ ID NO 1162 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1162: GGAATTTTAA CGCTCTTTTT 20(2) SEQ ID NO 1163 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1163: AAATCTCTGT GGGCTTAGTG 20(2) SEQ ID NO 1164 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO1164: AATCAAAAAC AAGAGCGTGG 20(2) SEQ ID NO 1165 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1165: GCCCCAGCCC CATAATACAA A21 (2) SEQ ID NO 1166 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1166: GGAGGGCGCA ATTAAACATC G21 (2) SEQ ID NO 1167information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1167: TCACGCTTTC TAAATCATCA 20(2) SEQ ID NO 1168 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1168: CGCTAATCAC ATCCTTTCTT 20(2) SEQ ID NO 1169 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1169: TGCCCAAAAA TCCACTAACG 20(2) SEQ ID NO 1170 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1170: AACGGGTTTG ACACTGATGA 20(2) information 1171

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1171: GAATGCGGTG GTTTTAGAGA G21 (2) information SEQ ID NO 1172

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1172: GCGTTTTTAA GACTGAATAC A21 (2) SEQ ID NO 1173 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1173: GGGCGATGTG ATTGGCGATT 20(2) SEQ ID NO 1174 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1174: GGATAGCCTG CCAAAACGCC 20(2) information SEQ ID NO 1175

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1175: AAGTTTATGC GGGCGAGATT 20(2) information SEQ ID NO 1176

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1176: GGAGCAATCA GCCATTTTTC 20(2) SEQ ID NO 1177 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1177: CTAGCGATTC AAGGCGATGG 20(2) information SEQ ID NO 1178

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1178: CGGCCTCCTT CAAACACATT 20(2) information SEQ ID NO 1179

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1179: AGCGGGCAGT TTAGGACCAC 20(2) SEQ ID NO 1180 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1180: GCATTGATCG CATTTTTAGC C21 (2) SEQ ID NO 1181 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1181: ACGGGTTAGC AGGGCAGAAT 20(2) SEQ ID NO 1182 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1182: CAAAAGAGGC GGGTTCATGC 20(2) SEQ ID NO 1183 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1183: TTTAGAAGTC GTTGATGAGA 20(2) SEQ ID NO 1184 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1184: CATACACGCT CACTTCATCG 20(2) SEQ ID NO 1185 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming:is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1185: AGTGTGGTCG CCTGTGGTGG AG 22(2) SEQ ID NO 1186 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1186: CCCCTAATAG TCTGTCAATC AT 22(2) SEQ ID NO 1187 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1187: CAAAAGATTG AAGCAGAAGA GT 22(2) SEQ ID NO 1188 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1188: AATGGTTTTC CTATACCCTT GA 22(2) SEQ ID NO 1189 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1189: GAGAGCAAAT CCTTATCCAG 20(2) information SEQ ID NO 1190

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1190: CATACACGCT CACTTCATCG 20(2) information SEQ ID NO 1191

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1191: AGTGTGGTCG CCTGTGGTGG AG 22(2) information SEQ ID NO 1192

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1192: CCCCTAATAG TCTGTCAATC AT 22(2) information SEQ ID NO 1193

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1193: CAAAAGATTG AAGCAGAAGA GT 22(2) information SEQ ID NO 1194

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1194: AATGGTTTTC CTATACCCTT GA 22(2) information SEQ ID NO 1195

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1195: TTGAAACCCC AAAAGTTTTA C21 (2) information SEQ ID NO 1196

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1196: TCAACTGATA GGTAATATCC C21 (2) information SEQ ID NO 1197

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1197: GCTAGGATTT ATGCCAATTT A21 (2) message SEQ ID NO 1198

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1198: TACGAGACAA AATAGGGATT T21 (2) information SEQ ID NO 1199

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1199: ATAGGCATGC AGAATTTTTC C21 (2) SEQ ID NO 1200 message

Sequence properties:

(A) length: 17 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...17

(xi) sequence representation: SEQ ID NO 1200: CCATTACATT TCGCCTC 17(2) SEQ ID NO 1201 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1201: CGATAGATAT TGTAGAAGTC A21 (2) SEQ ID NO 1202 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1202: GGGCTTGTAT TCATTTTGTA A21 (2) SEQ ID NO 1203 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1203: GTTTTAAAAA CGCCATAGCC A21 (2) SEQ ID NO 1204 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1204: TTCTAAAAGGTGGTAATCTT C21 (2) SEQ ID NO 1205 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO1205: TAAGTCAACC CATAAAACCA AA 22(2) SEQ ID NO 1206 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1206: TTTTGGGGTA AAAAGGCTGA A21 (2) SEQ ID NO 1207 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1207: ATCTTTTTGC CCTTGCTCAT A21 (2) SEQ ID NO 1208 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1208: AGACAGCACC AGTTTGATAA A21 (2) SEQ ID NO 1209 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1209: CAGCCACACT TCAATGTCTA T21 (2) SEQ ID NO 121O information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: 1210, GTAAGGCGTT AGAAAAATAC C21 (2) SEQ ID NO 1211 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: 1211: GCCCCATTAA AATCCTTTTC T21 (SEQ ID NO: 2) information 1212 (SEQ ID NO: 1212)

Sequence properties:

(A) length: 17 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...17

(xi) sequence representation: SEQ ID NO 1212: AAAGGATACA AGGGGGA 17(2) SEQ ID NO 1213 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1213: CTCGCTCCAT TTTATCTTTT A21 (2) SEQ ID NO 1214 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1214 TTTTTTAGGG AGGATTGAGA T21 (2) SEQ ID NO 1215 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1215: TGTTTGGAAA TGCTGGTGAT C21 (2) SEQ ID NO:1216 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1216: CTTTTGGGGG AGTTTGACAA C21 (2) SEQ ID NO 1217 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1217: TTTGATAAAC GCCCACTTTT T21 (2) SEQ ID NO 1218 message

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1218: TTTCAAAACG CTCACCTTTT G21 (2) SEQ ID NO 1219 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1219: TCTATTCTTT TGATGCTCTC T21 (2) SEQ ID NO 1220 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1220: ATAATGAGTT TGATCGTTAC G21 (2) SEQ ID NO 1221 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1221: ACAATAATAG GCTTTGTCTT C21 (2) SEQ ID NO 1222 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1222: AATTAGCCCT TAAAATAGAT G21 (2) SEQ ID NO 1223 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1223 AACAACCGCT AAAATCAAAC 20(2) SEQ ID NO 1224 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1224: CTTCAGCGAT ACTAAAAGAT 20(2) SEQ ID NO 1225 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1225: TAGGGGCGAT TGAAAACAGC 20(2) SEQ ID NO 1226 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1226: GCTGGATAAG GATTTGCTCT 20(2) SEQ ID NO 1227 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1227: TTTTTGGGGG TATGCTAAAA 20(2) SEQ ID NO 1228 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1228: GGCTGGTAAA TACTGGATAG 20(2) SEQ ID NO 1229 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1229: AGGCTATTCA AGGTGGCTAA A21 (2) SEQ ID NO 1230 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1230: ATTCTCATCA ACGACTTCTA AA 22(2) SEQ ID NO 1231 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1231: GCAGTTGCG GTATTTGGTG 20(2) SEQ ID NO 1232 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1232 GAGAGCGAAG TTTATGAGAA 20(2) SEQ ID NO 1233 message

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1233 TGATTGTTGG GTAGCTCTCA 20(2) SEQ ID NO 1234 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1234: AAAATCGGTC TGATGCTCTT A21 (2) SEQ ID NO 1235 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1235 CTTTTCCTTT CGCTTGAAGA 20(2) SEQ ID NO 1236 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix)feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1236 AAAACAAACG CATCAAAAAT 20(2) SEQ ID NO 1237 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1237 TTTCAAGGCG AGGAGGCAGA T21 (2) SEQ ID NO 1238 message

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1238 GCACAAAGAC CCCACCACGA T21 (2) SEQ ID NO 1239 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1239: CGCCCGAATG GATGAGTAGG 20(2) SEQ ID NO 1240 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1240: TGCAACAAAA ATACGCCCTT 20(2) SEQ ID NO 1241 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1241: TTTTTAAGGG CGTATTTTTG T21 (2) SEQ ID NO 1242 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1242: TGGGTTTTAA GGAATGTGAT G21 (2) SEQ ID NO 1243 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1243: CGCGCTCAAA ATCCCTAAAT 20(2) SEQ ID NO 1244 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation:SEQ ID NO 1244: GGCCCATTCT TTCGGATATT 20(2) SEQ ID NO 1245 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1245: GCCCCATTCC TGTTTTTAGC 20(2) SEQ ID NO 1246 information

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1246: CGCTTTAACG CTCCTTTCAC 20(2) SEQ ID NO 1247 information

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1247: AGCGTTTTTG TAAGGGGGTA T21 (2) information of SEQ ID NO 1248

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1248: TCCCTATCAT AGCGTTAGTG C21 (2) information of SEQ ID NO 1249

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1249: CTTAGGGGTT TTTAGCATGA A21 (2) information of SEQ ID NO 1250

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1250: GCACAATTCC CACACGCTGC 20(2) information of SEQ ID NO 1251

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1251: CCAAAGCTAA AGCGGTGTTT T21 (2) information of SEQ ID NO 1252

Sequence properties:

(A) length: 23 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...23

(xi) sequence representation: SEQ ID NO 1252: GCTCATGGAT ATAAAGGGGT ATT 23(2) information of SEQ ID NO 1253

Sequence properties:

(A) length:20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1253: CTTAGCCCCT TTAGTGTTTA 20(2) information of SEQ ID NO 1254

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1254: CGCAAAAGGG TAGGGGATAA 20(2) information of SEQ ID NO 1255

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1255: TTTTATTTTT AGAAACGAAT C21 (2) information of SEQ ID NO 1256

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1256: CAAACTTATC GCCCTCTCTA 20(2) information of SEQ ID NO 1257

Sequence properties:

(A) length: 23 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...23

(xi) sequence representation: SEQ ID NO 1257: AAAGATAACG CTAGGATTTC TAC 23(2) information of SEQ ID NO 1258

Sequence properties:

(A) length: 23 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...23

(xi) sequence representation: SEQ ID NO 1258: TAATTCTACA GAGTGGTTAA TGG 23(2) information of SEQ ID NO 1259

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1259: GCGGTCATGG AATTTTTAGA 20(2) SEQ ID NO 1260 information

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: 1260, ATTCAAAGAA AGCTGGCTGT CT 22(2) SEQ ID NO 1261

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO 1261: GCTTGTGGGG GTTGTTTTAT 20(2) information of SEQ ID NO 1262

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO:1262: GAACCCCCTA AAATGACAAT 20(2) information of SEQ ID NO:1263

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1263: ACCATGCTCATTAACGCTAG G21 (2) information of SEQ ID NO 1264

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1264: GTAAGTTTGA GCGGCTAATT C21 (2) information of SEQ ID NO 1265

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1265: AAAAAGAAAG AAGAACTCGT G21 (2) information of SEQ ID NO 1266

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO:1266: AAAGATACTC CCCTGTGATT A21 (2) information of SEQ ID NO:1267

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO:1267: CAAAGAAACG CAAAATACAG 20(2) information of SEQ ID NO:1268

Sequence properties:

(A) length: 20 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...20

(xi) sequence representation: SEQ ID NO:1268: GCATGGTATT CAGCGTTTTC 20(2) information of SEQ ID NO:1269

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ featute

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1269: GCAGCGGCAC AGCGACTTTA G21 (2) information of SEQ ID NO 1270

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1270: CGCCCCCAAA AAGTCGCAGT A21 (2) information of SEQ ID NO 1271

Sequence properties:

(A) length: 22 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: isfree of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...22

(xi) sequence representation: SEQ ID NO 1271: AAAGGTTTGA AACAAGAAAT CT 22(2) information of SEQ ID NO 1272

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1272: CACTTGAGCG TTAGCAACAA T21 (2) information of SEQ ID NO 1273

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1273: GGGGTGTTTG AAATTGATAG A21 (2) information of SEQ ID NO 1274

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1274: CGCTAGGAGA AAGGAAGGAA A21 (2) information of SEQ ID NO 1275

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1275: CAAGGGCGTT TTTTGGGGTA T21 (2) information of SEQ ID NO 1276

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1276: GGGATTGTTA CAGGAAAAGA T21 (2) information of SEQ ID NO 1277

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1277: GGAATACAAT AACGCATAAA T21 (2) information of SEQ ID NO 1278

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1278: GCCTTTTTAG ACAACCCTAC T21 (2) information of SEQ ID NO 1279

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1279: CCCCTAAACT CAAATCTCAA T21 (2) information of SEQ ID NO 1280

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1280: GCTAGAAATG CCATGAGAAA G21 (2) message of SEQ ID NO 1281

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1281: GCGATTATGG GGTATTTATT G21 (2) information of SEQ ID NO 1282

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1282: TTATTGTGGA GTTGCTTGTC A21 (2) information of SEQ ID NO 1283

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc_ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1283: TATGCGGCTC ATCCTATTAA A21 (2) information of SEQ ID NO 1284

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1284: CCCTAAATCC AAATCAAGCA C21 (2) information of SEQ ID NO 1285

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1285: ATCTTACCTA TCACCTCAAA T21 (2) information of SEQ ID NO 1286

Sequence properties:

(A) length: 21 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...21

(xi) sequence representation: SEQ ID NO 1286: AGACAGCAAC ATCTTTGTGA A21 (2) information of SEQ ID NO 1287

Sequence properties:

(A) length: 25 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...25

(xi) sequence representation: SEQ ID NO 1287: TTATGGATCC AAACCAATTA AAACT 25(2) information of SEQ ID NO 1288

Sequence properties:

(A) length: 23 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...23

(xi) sequence representation: SEQ ID NO 1288: TATCTCGAGT TATAGAGAAG GGC 23(2) information of SEQ ID NO 1289

Sequence properties:

(A) length: 29 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...29

(xi) sequence representation: SEQ ID NO 1289: AAATAGTCAT ATGAAAATAG GCGTTTTTG 29(2) information of SEQ ID NO 1290

Sequence properties:

(A) length: 28 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...28

(xi) sequence representation: 1290: AGAATTCTAT TACAATTTGA GCCATTCT 28(2) information of SEQ ID NO 1291

Sequence properties:

(A) length: 26 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1..26

(xi) sequence representation: 1291: GCGAATTCGA TCAGAATTTT TTTTCT 26(2) information of SEQ ID NO:1292

Sequence properties:

(A) length: 26 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...26

(xi) sequence representation: 1292: ATAAGTACTT GTGAATCTTA TACTAG 26(2) information of SEQ ID NO 1293

Sequence properties:

(A) length: 2694 base pairs

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2694

(xi) sequence representation: SEQ ID NO 1293: ATGGAGCAGC CAGTCATTAA AGAAGGGACT TTAGCTTTAA TTGATACCTT TGCGTATTTG 60TTTAGAAGCT ATTACATGAG CGCTAAAAAT AAGCCTTTAA CCAACGATAA GGGCTTTCCT 120ACAGGGCTTT TAACGGGGCT TGTGGGCATG GTTAAAAAAT TTTATAAAGA CAGAAAAAAC 180ATGCCTTTTA TCGTGTTCGC CCTAGAAAGC CAGACTAAAA CTAAAAGAGC TGAAAAACTG 240GGCGAATACA AACAAAATCG TAAAGACGCC CCTAAAGAGA TGCTTTTACA AATCCCTATC 300GCCTTAGAAT GGTTGCAAAA AATGGGTTTT ACTTGCGTGG AGGTGGGAGG GTTTGAAGCC 360GATGATGTGA TCGCAAGTTT AGCCACGCTA AGCCCTTATA AAACCCGCAT TTATTCTAAA 420GATAAGGATT TTAACCAGCT TTTGAGCGAT AAAATCGCGC TTTTTGATGG CAAAACGGAG 480TTTTTGGCGA AAGATTGCGT GGAAAAATAC GGGATTTTGC CGAGTCAATT CACGGATTAT 540CAGGGCATTG TGGGGGATAG CAGCGATAAT TACAAGGGGG TTAAAGGCAT TGGGAGCAAG 600AACGCTAAGG AATTGTTGCA GCGATTAGGG AGCTTGGAAA AAATCTATGA AAATTTAGAC 660TTGGCGAAAA ATTTACTCAG CCCTAAAATG TATCAAGCCT TGATACAAGA CAAAGGAAGC 720GCCTTTTTAA GCAAAGAATT AGCCACTTTA GAAAGAGGAT GCATTAAAGA ATTTGATTTT 780TTAAGTTGCG CTTTTCCGAG CGAAAACCCC TTGTTGAAAA TCAAAGATGA ATTGAAAGAA 840TATGGTTTCA TTTCTACCTT AAGGGATTTA GAAAATTCCC CTTTCATTGT AGAAAACGTG 900CCCATATTAA ACAGCACGCC TATATTAGAC AATACCCCCG CCTTAGACAA CGCCCCTAAA 960AAATCGCGCA TGATTGTTTT AGAAAGCGCT GAGCCTTTGA GCATGTTTTT AGAAAAATTA 1020GAAAACCCTA ACGCTAGGGT TTTTATGCGT TTGGTTTTGG ATAAAGACAA AAAAATTCTA 1080GCCCTAGCGT TTTTATTACA AGATCAAGGC TATTTTTTAC CTTTAGAAGA GGCGTTGTTT 1140TCGCCCTTTT CTTTGGAATT TTTACAAAAC GCTTTTTCTC AAATGTTACA GCATGCGTGT 1200ATCATTGGGC ATGATTTAAA GCCTTTATTA AGCTTTTTAA AAGCCAAATA TCAGGTGCCT 1260TTGGAAAATA TCCGCATCCA AGACACTCAG ATTTTAGCGT TTTTAAAGAA TCCGGAAAAA 1320GTGGGGTTTG ATGAGGTTTT AAAGGAATAT TTAAAAGAAG ATTTAATCCC GCATGAAAAG 1380ATCAAAGATT TTAAGACAAA AAGTAAGGCG GAAAAATCAG AACTTTTAAG CATGGAATTA 1440AACGCCTTAA AGCGTTTGTG CGAATACTTT GAAAAAGGGG GGCTAGAAGA GGATTTGCTC 1500ACTTTAGCTA GAGACATTGA AACGCCGTTT GTGAAAGTTT TAATGGGCAT GGAATTTCAA 1560GGCTTTAAGA TTGATGCGCC TTATTTCAAG CGCTTAGAGC AGGAGTTTAA GAATGAATTA 1620AACGTTTTAG AGCGCCAAAT TTTGGATCTA ATCGGCGTGG ATTTCAACCT CAATTCGCCC 1680AAGCAACTTG GCGAAGTCTT GTATGATAAA TTAGGGCTTC CTAAAAATAA AAGCCACTCT 1740ACCGATGAAA AAAACTTGTT AAAAATCCTA GACAAGCACC CAAGCATCCC TTTGATTTTA 1800GAATACAGGG AATTGAATAA GCTTTTTAAC ACTTACACGA CCCCCTTATT GCGCTTAAAA 1860GACAAAGACG ATAAAATCCA TACCACTTTC ATCCAAACCG GCACAGCTAC CGGGCGTTTA 1920AGCTCGCATT CGCCTAATTT GCAAAATATC CCGGTGCGAT CGCCTAAAGG CTTACTCATT 1980CGTAAGGGTT TTATCGCTAG CTCTAAAGAA TATTGTTTAT TAGGGGTGGA TTATTCGCAG 2040ATTGAATTAC GCTTGTTGGC CCATTTCAGC CAGGATAAGG ATTTAATGGA AGCGTTTTTA 2100AAGGGGCGAG ACATCCATTT AGAAACTTCT AAGGCGTTGT TTGGAGAAGA TTTAGCCAAA 2160GAAAAACGAT CCATCGCTAA AAGCATTAAT TTTGGGCTGG TGTATGGCAT GGGGAGTAAG 2220AAATTGAGCG AAACTTTAAG CATCCCTTTA AGTGAGCCTA AAAGTTACAT AGAAGCGTAT 2280TTCAAGCGAT TCCCTAGCAT TAAAGATTAT TTGAATGGCA TGCGAGAAGA GATTTTAAAA 2340ACTTCTAAAG CTTTTACTTT GCTGGGGCGT TACCGGGTGT TTGATTTTAC CGGCGTGAAT 00 2400GATTATGTCA AGGGCAATTA TTTGCGAGAG GGCGTGAATG CGATTTTTCA AGGGAGTGCC 2460 2520GTGAGGCTGC TTTTGCAAGT GCATGACGAA TTGATTTTTG AAATTGAAGA AAAAAACGCC 2580CCAGAGTTGC AGCAAGAAAT CCAACGCATT CTTAATGATG AAGTCTATCC TTTGAGGGTG 2640CCGTTAGAAA CAAGCGCGTT TATCGCTAAG CGTTGGAATG AATTAAAAGG TTAG 2694(2) information of SEQ ID NO:1294

Sequence properties:

(A) length: 2007 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...2007

(xi) sequence representation: SEQ ID NO 1294: ATGAAAAAAC CCTTTTACTC TCTCTCTCTC GCTTCATCGC TTTTAAACGC TGAAGACAAC 60GGCTTTTTTA TCAGCGCGGG CTATCAAATC GGTGAAGCCG CTCAAATGGT GAAAAACACC 120GGCGAATTGA AAAAACTTTC AGACACTTAT GAGAATTTGA GCAACCTTTT AACCAATTTT 180AACAACCTCA ATCAGGCGGT AACGAACGCG AGCAGCCCTT CAGAAATCAA TGCTGCGATC 240GATAATTTAA AAGCAAACAC GCAAGGGCTA ATTGGCGAAA AAACCAATTC CCCGGCGTAT 300CAAGCGGTGT ATTTGGCGCT CAATGCGGCG GTAGGGCTGT GGAATGTCAT CGCCTATAAT 360GTCCAATGCG GTCCTGGTAA CAGTGGACAA CAAAGCGTAA CCTTTGAGGG CCAACCAGGA 420CATAATTCAA GTTCCATTAA TTGCAATTTA ACCGGTTATA ACAACGGGGT TAGCGGCCCT 480TTATCCATTG AGAATTTTAA AAAGCTTAAT CAGGCTTATC AAACTATCCA ACAAGCTTTA 540AAACAAGATA GCGGATTTCC TGTTTTGGAT AGTGCAGGAA AACAAGTAAC TATAACAATA 600ACAACGCAAA CTAATGGAGC TAATAAAAGT GAAACTACTA CTACTACTAC TACTACTAAT 660GACGCTCAAA CCCTTTTGCA AGAAGCCAGT AAAATGATAA GCGTCCTCAC TACAAACTGC 720CCATGGGTCA ATCACAATCA AGGACAAAAC GGGGGCGCGC CGTGGGGTTT AGATACGGCA 780GGGAATGTGT GTCAGGTTTT TGCCACGGAA TTTAGCGCCG TTACTAGCAT GATCAAAAAC 840GCCCAAGAAA TCGTAACGCA AGCTCAAAGC CTTAACCAGC AAAACAATCA AA ACGCGCCG 900CAAGATTTCA ATCCTTACAC CTCTGCTGAT AGGGCTTTCG CTCAAAACAT GCTCAATCAC 960GCGCAAGCGC AAGCCAAGAT ACTTGAGCTA GCCGATCAAA TGAAAAAAGA CCTTAACACT 1020ATCCCAAGCC AATTTATCAC AAATTACTTG GCAGCTTGCC ACAATGGGGG TGGGACATTA 1080CCTGATGCGG GGGTTACTAA CAACACTTGG GGGGCCGGTT GCGCGTATGT GGAAGAGACG 1140ATAACGGCTT TAAACAACAG CCTTGCGCAT TTTGGCACTC AAGCTGAGCA AATCAAGCAA 1200TCTGAGTTGT TGGCGCGCAC CATACTTGAT TTTAGAGGCA GCCTTAGTAA TTTAAACAAC 1260ACTTATAACA GCATCACCAC GACCGCTTCA AACACGCCTA ATTCCCCATT CCTTAAAAAT 1320TTGATAAGCC AATCCACTAA CCCTAATAAC CCCGGGGGCT TACAGGCCGT TTATCAAGTC 1380AACCAAAGCG CTTATTCGCA ATTATTAAGC GCCACGCAAG AATTAGGGCA TAACCCTTTC 1440AGACGCGTTG GATTAATCAG CTCTCAAACC AACAATGGTG CCATGAATGG GATCGGTGTG 1500CAAGTGGGCT ACAAACAATT TTTTGGTGAA AAGAGAAGGT GGGGGTTAAG GTATTACGGC 1560TTTTTTGACT ATAACCATGC TTATATCAAA TCTAGCTTTT TCAATTCGGC TTCTGATGTG 1620TTCACTTATG GGGTAGGGAC AGATGTCCTC TATAACTTTA TCAATGATAA AACCACCAAA 1680AACAGCAAGA TTTCTTTTGG GGTGTTTGGG GGGATTGCGT TAGCTGGCAC TTCATGGCTG 1740AATTCCCAGT ATGTGAATTT AGCGACCTTC AATAATTTCT ATAGCGCTAA AATGAATGTG 1800GCGAATTTCC AATTCTTGTT CAATTTAGGC TTGAGAATGA ACCTCGCTAA GAATAAGAAA 1860AAAGCGAGCG ATCATGCGGC TCAGCATGGC GTGGAATTAG GCGTGAAGAT CCCCACGATC 1920AACACGAATT ACTATTCTTT GCTAGGCACT CAACTCCAAT ACCGAAGATT GTATAGCGTG 1980TATTTGAATT ATGTGTTCGC TTACTAA 2007(2) the information of SEQ ID NO:1295

Sequence properties:

(A) length: 1914 base pair

(B) Type (2): nucleic acids

(C) Chain type: double chain

(D) Topological configuration: ring type

(ii) type of molecule: DNA (genome)

(iii) assuming: is not

(iv) antisense strand: is free of

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...1914

(xi) sequence representation: SEQ ID NO 1295: ATGAAAAGAC AATTCTACTC TCTCTCTCTC TCTCTCGCTT CATCGCTCTT GCATGCTGAA 60GACAACGGCT TTTTTGTGAG CGCGGGCTAT CAAATCGGCG AAGCGGTGCA AATGGTCAAA 120AACACCGGCG AATTGAAAAA CTTGAACGAC AAATACGAGC AGTTAAGCCA ATCTTTAGCC 180CAACTGGCTT CGTTAAAAAA AAGCATTCAA ACGGCGAACA ACATTCAGGC TGTCAACAAT 240GCTTTAAGCG ATTTAAAAAG CTTTGCGAGT AACAACCACA CAAACAAAGA AACATCGCCC 300ATCTACAACA CCGCGCAAGC TGTTATCACT TCAGTATTGG CTTTTTGGAG TCTTTATGCA 360GGGAACGCTC TCAGTTTTCA TGTGACCGGT TTGAATGATG GATCTAATTC TCCTTTAGGA 420AGAATCCATA GAGATGGGAA CTGCACAGGA TTACAACAAT GTTTTATGAG CAAAGAAACT 480TATGATAAAA TGAAGACACT TGCCGAAAAC CTCCAAAAAG CTCAAGGCAA TCTCTGTGCC 540TTATCAGAAT GCTCTAGCAA TCAATCAAAT GGAGGCAAAA CTTCCATGAC TACAGCTCTT 600CAAACCGCGC AACAGCTCAT GGACTTAATC GAACAGACCA AGGTTTCTAT GGTGTGGAAA 660AATATCGTCA TCGCAGGTGT TACAAACAAA CCCAATGGTG CTGGCGCTAT CACATCCACT 720GGTCATGTAA CCGACTATGC GGTGTTTAAC AACATCAAGG CGATGCTACC TATCTTGCAA 780CAAGCGCTTA CGCTTTCTCA AAGTAACCAC ACCCTATCCA CTCAGTTGCA AGCTCGAGCT 840ATGGGATCTC AAACAAATCG TGAATTCGCT AAAGACATCT ACGCTTTAGC TCAAAACCAA 900AAGCAAATCC TTTCTAACGC TTCAAGTATC TTCAATCTCT TTAATTCCAT TCCTAAAGAC 960CAACTTAAGT ATTTGGAGAA CGCTTACTTG AAAGTGCCAC ATTTGGGTAA AACCCCTACT 1020AACCCTTACA GACAGAATGT GAATTTGAAT AAAGAAATTA ATGCGGTTCA AGACAATGTA 1080GCTAATTATG GTAATCGTTT GGATTCGGCT TTAAGCGTGG CTAAAGATGT TTATAACCTA 1140AAATCCAATC AAACAGAGAT CGTAACCACT TATAACGATG CTAAGAATTT GAGCGAAGAG 1200ATTTCTAAAC TTCCCTATAA CCAAGTCAAT GTAACAAACA TCGTTATGTC GCCTAAAGAT 1260TCTACAGCGG GCCAATACCA AATCAACCCA GAGCAGCAAT CCAATCTTAA CCAAGCTTTA 1320GCGGCGATGA GCAATAACCC CTTTAAAAAA GTGGGCATGA TCAGCTCTCA AAACAATAAC 1380GGCGCTTTGA ACGGGCTTGG CGTGCAAGTG GGTTATAAAC AATTCTTTGG CGAAAGCAAA 1440AGATGGGGGT TAAGGTATTA TGGTTTCTTT GATTACAACC ACGGCTATAT CAAATCCAGC 1500TTTTTTAATT CTTCTTCTGA TATATGGACT TATGGCGGTG GGAGCGATTT GTTAGTGAAT 1560TTTATCAACG ATAGCATCAC AAGAAAGAAC AACAAGCTTT CTGTGGGTCT TTTTGGTGGT 1620ATCCAACTAG CAGGGACTAC ATGGCTTAAT TCTCAATACA TGAATTTAAC AGCGTTCAAT 1680AACCCTTACA GCGCGAAAGT CAATGCTTCC AATTTCCAAT TTTTGTTCAA TCTCGGCTTG 1740AGGACGAATC TCGCTACAGC TAAGAAAAAA GACAGCGAAC GTTCCGCGCA ACATGGCGTT 1800GAACTGGGCA TTAAAATCCC TACCATTAAC ACCAATTATT ATTCTTTTCT AGGCACTAAG 1860CTAGAATACC GAAGGCTTTA TAGCGTGTAT CTCAATTATG TGTTTGCTTA TTAA 1914(2) information of SEQ ID NO:1296

Sequence properties:

(A) length: 897 amino acid

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...897

(xi) sequence representation: SEQ ID NO 1296: Met Glu Gln Pro Val Ile Lys Glu Gly Thr Leu Ala Leu Ile Asp Thr 151015 Phe Ala Tyr Leu Phe Arg Ser Tyr Tyr Met Ser Ala Lys Asn Lys Pro

20 25 30Leu Thr Asn Asp Lys Gly Phe Pro Thr Gly Leu Leu Thr Gly Leu Val

35 40 45Gly Met Val Lys Lys Phe Tyr Lys Asp Arg Lys Asn Met Pro Phe Ile

50 55 60Val Phe Ala Leu Glu Ser Gln Thr Lys Thr Lys Arg Ala Glu Lys Leu65 70 75 80Gly Glu Tyr Lys Gln Asn Arg Lys Asp Ala Pro Lys Glu Met Leu Leu

85 90 95Gln Ile Pro Ile Ala Leu Glu Trp Leu Gln Lys Met Gly Phe Thr Cys

100 105 110Val Glu Val Gly Gly Phe Glu Ala Asp Asp Val Ile Ala Ser Leu Ala

115 120 125Thr Leu Ser Pro Tyr Lys Thr Arg Ile Tyr Ser Lys Asp Lys Asp Phe

130 135 140Asn Gln Leu Leu Ser Asp Lys Ile Ala Leu Phe Asp Gly Lys Thr Glu145 150 155 160Phe Leu Ala Lys Asp Cys Val Glu Lys Tyr Gly Ile Leu Pro Ser Gln

165 170 175Phe Thr Asp Tyr Gln Gly Ile Val Gly Asp Ser Ser Asp Asn Tyr Lys

180 185 190Gly Val Lys Gly Ile Gly Ser Lys Asn Ala Lys Glu Leu Leu Gln Arg

195 200 205Leu Gly Ser Leu Glu Lys Ile TyrGlu Asn Leu Asp Leu Ala Lys Asn

210 215 220Leu Leu Ser Pro Lys Met Tyr Gln Ala Leu Ile Gln Asp Lys Gly Ser225 230 235 240Ala Phe Leu Ser Lys Glu Leu Ala Thr Leu Glu Arg Gly Cys Ile Lys

245 250 255Glu Phe Asp Phe Leu Ser Cys Ala Phe Pro Ser Glu Asn Pro Leu Leu

260 265 270Lys Ile Lys Asp Glu Leu Lys Glu Tyr Gly Phe Ile Ser Thr Leu Arg

275 280 285Asp Leu Glu Asn Ser Pro Phe Ile Val Glu Asn Val Pro Ile Leu Asn

290 295 300Ser Thr Pro Ile Leu Asp Asn Thr Pro Ala Leu Asp Asn Ala Pro Lys305 310 315 320Lys Ser Arg Met Ile Val Leu Glu Ser Ala Glu Pro Leu Ser Met Phe

325 330 335Leu Glu Lys Leu Glu Asn Pro Asn Ala Arg Val Phe Met Arg Leu Val

340 345 350Leu Asp Lys Asp Lys Lys Ile Leu Ala Leu Ala Phe Leu Leu Gln Asp

355 360 365Gln Gly Tyr Phe Leu Pro Leu Glu Glu Ala Leu Phe Ser Pro Phe Ser

370 375 380Leu Glu Phe Leu Gln Asn Ala Phe Ser Gln Met Leu Gln His Ala Cys385 390 395 400Ile Ile Gly His Asp Leu Lys Pro Leu Leu Ser Phe Leu Lys Ala Lys

405 410 415Tyr Gln Val Pro Leu Glu Asn Ile Arg Ile Gln Asp Thr Gln Ile Leu

420 425 430Ala Phe Leu Lys Asn ProGlu Lys Val Gly Phe Asp Glu Val Leu Lys

435 440 445Glu Tyr Leu Lys Glu Asp Leu Ile Pro His Glu Lys Ile Lys Asp Phe

450 455 460Lys Thr Lys Ser Lys Ala Glu Lys Ser Glu Leu Leu Ser Met Glu Leu465 470 475 480Asn Ala Leu Lys Arg Leu Cys Glu Tyr Phe Glu Lys Gly Gly Leu Glu

485 490 495Glu Asp Leu Leu Thr Leu Ala Arg Asp Ile Glu Thr Pro Phe Val Lys

500 505 510Val Leu Met Gly Met Glu Phe Gln Gly Phe Lys Ile Asp Ala Pro Tyr

515 520 525Phe Lys Arg Leu Glu Gln Glu Phe Lys Asn Glu Leu Asn Val Leu Glu

530 535 540Arg Gln Ile Leu Asp Leu Ile Gly Val Asp Phe Asn Leu Asn Ser Pro545 550 555 560Lys Gln Leu Gly Glu Val Leu Tyr Asp Lys Leu Gly Leu Pro Lys Asn

565 570 575Lys Ser His Ser Thr Asp Glu Lys Asn Leu Leu Lys Ile Leu Asp Lys

580 585 590His Pro Ser Ile Pro Leu Ile Leu Glu Tyr Arg Glu Leu Asn Lys Leu

595 600 605Phe Asn Thr Tyr Thr Thr Pro Leu Leu Arg Leu Lys Asp Lys Asp Asp

610 615 620Lys Ile His Thr Thr Phe Ile Gln Thr Gly Thr Ala Thr Gly Arg Leu625 630 635 640Ser Ser His Ser Pro Asn Leu Gln Asn Ile Pro Val Arg Ser Pro Lys

645 650 655Gly Leu Leu Ile Arg Lys Gly Phe Ile Ala Ser Ser Lys Glu Tyr Cys

660 665 670Leu Leu Gly Val Asp Tyr Ser Gln Ile Glu Leu Arg Leu Leu Ala His

675 680 685Phe Ser Gln Asp Lys Asp Leu Met Glu Ala Phe Leu Lys Gly Arg Asp

690 695 700Ile His Leu Glu Thr Ser Lys Ala Leu Phe Gly Glu Asp Leu Ala Lys705 710 715 720Glu Lys Arg Ser Ile Ala Lys Ser Ile Asn Phe Gly Leu Val Tyr Gly

725 730 735Met Gly Ser Lys Lys Leu Ser Glu Thr Leu Ser Ile Pro Leu Ser Glu

740 745 750Ala Lys Ser Tyr Ile Glu Ala Tyr Phe Lys Arg Phe Pro Ser Ile Lys

755 760 765Asp Tyr Leu Asn G1y Met Arg Glu Glu Ile Leu Lys Thr Ser Lys Ala

770 775 780Phe Thr Leu Leu Gly Arg Tyr Arg Val Phe Asp Phe Thr Gly Val Asn785 790 795 800Asp Tyr Val Lys Gly Asn Tyr Leu Arg Glu Gly Val Asn Ala Ile Phe

805 810 815Gln Gly Ser Ala Ser Asp Leu Leu Lys Leu Gly Met Leu Lys Val Ser

820 825 830Glu Arg Phe Lys Asn Asn Pro Ser Val Arg Leu Leu Leu Gln Val His

835 840 845Asp Glu Leu Ile Phe Glu Ile Glu Glu Lys Asn Ala Pro Glu Leu Gln

850 855 860Gln Glu Ile Gln Arg Ile Leu Asn Asp Glu Val Tyr Pro Leu Arg Val865 870 875 880Pro Leu Glu Thr Ser Ala Phe Ile Ala Lys Arg Trp Asn Glu Leu Lys

885890895 Gly (2) SEQ ID NO:1297

Sequence properties:

(A) length: 668 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...668

(xi) sequence representation: SEQ ID NO 1297: Met Lys Lys Pro Phe Tyr Ser Leu Ser Leu Ala Ser Ser Leu Leu Asn 151015 Ala Glu Asp Asn Gly Phe Phe Ile Ser Ala Gly Tyr Gln Ile Gly Glu

20 25 30Ala Ala Gln Met Val Lys Asn Thr Gly Glu Leu Lys Lys Leu Ser Asp

35 40 45Thr Tyr Glu Asn Leu Ser Asn Leu Leu Thr Asn Phe Asn Asn Leu Asn

50 55 60Gln Ala Val Thr Asn Ala Ser Ser Pro Ser Glu Ile Asn Ala Ala Ile65 70 75 80Asp Asn Leu Lys Ala Asn Thr Gln Gly Leu Ile Gly Glu Lys Thr Asn

85 90 95Ser Pro Ala Tyr Gln Ala Val Tyr Leu Ala Leu Asn Ala Ala Val Gly

100 105 110Leu Trp Asn Val Ile Ala Tyr Asn Val Gln Cys Gly Pro Gly Asn Ser

115 120 125Gly Gln Gln Ser Val Thr Phe Glu Gly Gln Pro Gly HisAsn Ser Ser

130 135 140Ser Ile Asn Cys Asn Leu Thr Gly Tyr Asn Asn Gly Val Ser Gly Pro145 150 155 160Leu Ser Ile Glu Asn Phe Lys Lys Leu Asn Gln Ala Tyr Gln Thr Ile

165 170 175Gln Gln Ala Leu Lys Gln Asp Ser Gly Phe Pro Val Leu Asp Ser Ala

180 185 190Gly Lys Gln Val Thr Ile Thr Ile Thr Thr Gln Thr Asn Gly Ala Asn

195 200 205Lys Ser Glu Thr Thr Thr Thr Thr Thr Thr Thr Asn Asp Ala Gln Thr

210 215 220Leu Leu Gln Glu Ala Ser Lys Met Ile Ser Val Leu Thr Thr Asn Cys225 230 235 240Pro Trp Val Asn His Asn Gln Gly Gln Asn Gly Gly Ala Pro Trp Gly

245 250 255Leu Asp Thr Ala Gly Asn Val Cys Gln Val Phe Ala Thr Glu Phe Ser

260 265 270Ala Val Thr Ser Met Ile Lys Asn Ala Gln Glu Ile Val Thr Gln Ala

275 280 285Gln Ser Leu Asn Gln Gln Asn Asn Gln Asn Ala Pro Gln Asp Phe Asn

290 295 300Pro Tyr Thr Ser Ala Asp Arg Ala Phe Ala Gln Asn Met Leu Asn His305 310 315 320Ala Gln Ala Gln Ala Lys Ile Leu Glu Leu Ala Asp Gln Met Lys Lys

325 330 335Asp Leu Asn Thr Ile Pro Ser Gln Phe Ile Thr Asn Tyr Leu Ala Ala

340 345 350Cys His Asn Gly Gly Gly Thr Leu Pro Asp Ala Gly Val Thr Asn Asn

355 360 365Thr Trp Gly Ala Gly Cys Ala Tyr Val Glu Glu Thr Ile Thr Ala Leu

370 375 38CAsn Asn Ser Leu Ala His Phe Gly Thr Gln Ala Glu Gln Ile Lys Gln385 390 395 400Ser Glu Leu Leu Ala Arg Thr Ile Leu Asp Phe Arg Gly Ser Leu Ser

405 410 415Asn Leu Asn Asn Thr Tyr Asn Ser Ile Thr Thr Thr Ala Ser Asn Thr

420 425 430Pro Asn Ser Pro Phe Leu Lys Asn Leu Ile Ser Gln Ser Thr Asn Pro

435 440 445Asn Asn Pro Gly Gly Leu Gln Ala Val Tyr Gln Val Asn Gln Ser Ala

450 455 460Tyr Ser Gln Leu Leu Ser Ala Thr Gln Glu Leu Gly His Asn Pro Phe465 470 475 480Arg Arg Val Gly Leu Ile Ser Ser Gln Thr Asn Asn Gly Ala Met Asn

485 490 495Gly Ile Gly Val Gln Val Gly Tyr Lys Gln Phe Phe Gly Glu Lys Arg

500 505 510Arg Trp Gly Leu Arg Tyr Tyr Gly Phe Phe Asp Tyr Asn His Ala Tyr

515 520 525Ile Lys Ser Ser Phe Phe Asn Ser Ala Ser Asp Val Phe Thr Tyr Gly

530 535 540Val Gly Thr Asp Val Leu Tyr Asn Phe Ile Asn Asp Lys Thr Thr Lys545 550 555 560Asn Ser Lys Ile Ser Phe Gly Val Phe Gly Gly Ile Ala Leu Ala Gly

565 570 575Thr Ser Trp Leu Asn Ser Gln Tyr Val Asn Leu Ala Thr Phe Asn Asn

580 585 590Phe Tyr Ser Ala Lys Met Asn Val Ala Asn Phe Gln Phe Leu Phe Asn

595 600 605Leu Gly Leu Arg Met Asn Leu Ala Lys Asn Lys Lys Lys Ala Ser Asp

610 615 620His Ala Ala Gln His Gly Val Glu Leu Gly Val Lys Ile Pro Thr Ile625 630 635 640Asn Thr Asn Tyr Tyr Ser Leu Leu Gly Thr Gln Leu Gln Tyr Arg Arg

645 650 655Leu Tyr Ser Val Tyr Leu Asn Tyr Val Phe Ala Tyr

660665 (2) information of SEQ ID NO:1298

Sequence properties:

(A) length: 637 amino acids

(B) Type (2): amino acids

(D) Topological configuration: wire type

(ii) type of molecule: protein

(iii) assuming: is that

(vi) original sources:

(A) an organism: helicobacter pylori

(ix) feature:

(A) name/keyword: misc _ feature

(B) Position: 1...637

(xi) sequence representation: SEQ ID NO:1298: Met Lys Arg Gln Phe Tyr Ser Leu Ser Leu Ser Leu Ala Ser Ser Leu 151015: Leu His Ala Glu Asp Asn Gly Phe Phe Val Ser Ala Gly Tyr Gln Ile

20 25 30Gly Glu Ala Val Gln Met Val Lys Asn Thr Gly Glu Leu Lys Asn Leu

35 40 45Asn Asp Lys Tyr Glu Gln Leu Ser Gln Ser Leu Ala Gln Leu Ala Ser

50 55 60Leu Lys Lys Ser Ile Gln Thr Ala Asn Asn Ile Gln Ala Val Asn Asn65 70 75 80Ala Leu Ser Asp Leu Lys Ser Phe Ala Ser Asn Asn His Thr Asn Lys

85 90 95Glu Thr Ser Pro Ile Tyr Asn Thr Ala Gln Ala Val Ile Thr Ser Val

100 105 110Leu Ala Phe Trp Ser Leu Tyr Ala Gly Asn Ala Leu Ser Phe His Val

115 120 125Thr Gly Leu Asn Asp Gly Ser Asn Ser Pro Leu Gly Arg Ile His Arg

130 135 140Asp Gly Asn Cys Thr Gly Leu Gln Gln Cys Phe Met Ser Lys Glu Thr145 150 155 160Tyr Asp Lys Met Lys Thr Leu Ala Glu Asn Leu Gln Lys Ala Gln Gly

165 170 175Asn Leu Cys Ala Leu Ser Glu Cys Ser Ser Asn Gln Ser Asn Gly Gly

180 185 190Lys Thr Ser Met Thr Thr Ala Leu Gln Thr Ala Gln Gln Leu Met Asp

195 200 205Leu Ile Glu Gln Thr Lys Val Ser Met Val Trp Lys Asn Ile Val Ile

210 215 220Ala Gly Val Thr Asn Lys Pro Asn Gly Ala Gly Ala Ile Thr Ser Thr225 230 235 240Gly His Val Thr Asp Tyr Ala Val Phe Asn Asn Ile Lys Ala Met Leu

245 250 255Pro Ile Leu Gln Gln Ala Leu Thr Leu Ser Gln Ser Asn His Thr Leu

260 265 270Ser Thr Gln Leu Gln Ala Arg Ala Met Gly Ser Gln Thr Asn Arg Glu

275 280 285Phe Ala Lys Asp Ile Tyr Ala Leu Ala Gln Asn Gln Lys Gln Ile Leu

290 295 300Ser Asn Ala Ser Ser Ile Phe Asn Leu Phe Asn Ser Ile Pro Lys Asp305 310 315 320Gln Leu Lys Tyr Leu Glu Asn Ala Tyr Leu Lys Val Pro His Leu Gly

325 330 335Lys Thr Pro Thr Asn Pro Tyr Arg Gln Asn Val Asn Leu Asn Lys Glu

340 345 350Ile Asn Ala Val Gln Asp Asn Val Ala Asn Tyr Gly Asn Arg Leu Asp

355 360 365Ser Ala Leu Ser Val Ala Lys Asp Val Tyr Asn Leu Lys Ser Asn Gln

370 375 380Thr Glu Ile Val Thr Thr Tyr Asn Asp Ala Lys Asn Leu Ser Glu Glu385 390 395 400Ile Ser Lys Leu Pro Tyr Asn Gln Val Asn Val Thr Asn Ile Val Met

405 410 415Ser Pro Lys Asp Ser Thr Ala Gly Gln Tyr Gln Ile Asn Pro Glu Gln

420 425 430Gln Ser Asn Leu Asn Gln Ala Leu Ala Ala Met Ser Asn Asn Pro Phe

435 440 445Lys Lys Val Gly Met Ile Ser Ser Gln Asn Asn Asn Gly Ala Leu Asn

450 455 460Gly Leu Gly Val Gln Val Gly Tyr Lys Gln Phe Phe Gly Glu Ser Lys465 470 475 480Arg Trp Gly Leu Arg Tyr Tyr Gly Phe Phe Asp Tyr Asn His Gly Tyr

485 490 495Ile Lys Ser Ser Phe Phe Asn Ser Ser Ser Asp Ile Trp Thr Tyr Gly

500505 510Gly Gly Ser Asp Leu Leu Val Asn Phe Ile Asn Asp Ser Ile Thr Arg

515 520 525Lys Asn Asn Lys Leu Ser Val Gly Leu Phe Gly Gly Ile Gln Leu Ala

530 535 540Gly Thr Thr Trp Leu Asn Ser Gln Tyr Met Asn Leu Thr Ala Phe Asn545 550 555 560Asn Pro Tyr Ser Ala Lys Val Asn Ala Ser Asn Phe Gln Phe Leu Phe

565 570 575Asn Leu Gly Leu Arg Thr Asn Leu Ala Thr Ala Lys Lys Lys Asp Ser

580 585 590Glu Arg Ser Ala Gln His Gly Val Glu Leu Gly Ile Lys Ile Pro Thr

595 600 605Ile Asn Thr Asn Tyr Tyr Ser Phe Leu Gly Thr Lys Leu Glu Tyr Arg

610 615 620Arg Leu Tyr Ser Val Tyr Leu Asn Tyr Val Phe Ala Tyr625 630 635

Claims (130)

1. An isolated nucleic acid comprising a nucleotide sequence encoding a helicobacter pylori polypeptide selected from the group consisting of: SEQ ID NO:492 to SEQ ID NO:759, SEQ ID NO:761, SEQ ID NO:763, SEQ ID NO:765 to SEQ ID NO:818, SEQ ID NO:820 to SEQ ID NO:846, SEQ ID NO:848 to SEQ ID NO:896, SEQ ID NO:898 to SEQ ID NO:963, SEQ ID NO:966 to SEQ ID NO:982, SEQ ID NO:1037, SEQ ID NO:1038, SEQ ID NO:1041 to SEQ ID NO:1087, SEQ ID NO:1090, and SEQ ID NO:1296 to SEQ ID NO: 1298.

2. A recombinant expression vector comprising the nucleic acid of claim 1 operably linked to a transcriptional regulatory element.

3. A cell comprising the recombinant expression vector of claim 2.

4. A method of producing a helicobacter pylori polypeptide, comprising culturing the cell of claim 3 under conditions that allow expression of the polypeptide.

5. A probe comprising a nucleotide sequence consisting of at least 8 nucleotides selected from the group consisting of SEQ ID NO 1-268, SEQ ID NO 270, SEQ ID NO 272, SEQ ID NO 274-327, SEQ ID NO 329-364, SEQ ID NO 366-405, SEQ ID NO 407-472, SEQ ID NO 475-491, SEQ ID NO 983, SEQ ID NO 984, SEQ ID NO 987-1033, SEQ ID NO 1036 and SEQ ID NO 1293-SEQ ID NO 1295 or a complementary sequence thereof.

6. An isolated nucleic acid comprising a nucleotide sequence of at least 8 nucleotides in length, wherein the sequence is capable of hybridizing to a nucleic acid comprising a nucleotide sequence selected from the group consisting of: 1-268, 270, 272, 274-327, 329-364, 405, 407-472, 475-491, 983, 984, 987-1033, 1036, and 1293-1295 or their complements.

7. A vaccine composition for the prevention or treatment of helicobacter pylori infection, comprising an effective amount of an isolated nucleic acid comprising a nucleotide sequence encoding a helicobacter pylori polypeptide or a fragment thereof, said nucleic acid comprising a nucleotide sequence selected from the group consisting of: SEQ ID NO. 1-SEQ ID NO. 268, SEQ ID NO. 270, SEQ ID NO. 272, SEQ ID NO. 274-SEQ ID NO. 327, SEQ ID NO. 329-SEQ ID NO. 364, SEQ ID NO. 366-SEQ ID NO. 405, SEQ ID NO. 407-SEQ ID NO. 472, SEQ ID NO. 475-SEQ ID NO. 491, SEQ ID NO. 983, SEQ ID NO. 984, SEQ ID NO. 987-SEQ ID NO. 1033, SEQ ID NO. 1036, and SEQ ID NO. 1293-SEQ ID NO. 1295.

8. The vaccine composition of claim 7, further comprising a pharmaceutically acceptable carrier.

9. The vaccine composition of claim 8, wherein the pharmaceutically acceptable carrier is an adjuvant.

10. A method of treating helicobacter pylori infection in a subject, comprising administering to the subject the vaccine composition of claim 7, thereby producing treatment for the helicobacter pylori infection.

11. The method of claim 10, wherein the treatment is a prophylactic treatment.

12. The method of claim 10, wherein the treatment is a therapeutic treatment.

13. A method of detecting the presence of a helicobacter nucleic acid in a sample, comprising,

(a) contacting the sample with the probe of claim 5 under conditions whereby a hybridisation product is formed between the probe and the helicobacter nucleic acid in the sample; and are

(b) Detecting the hybridization product formed in step (a), wherein detection of the hybridization product indicates the presence of helicobacter nucleic acid in the sample.

14. A recombinant or substantially pure preparation of a helicobacter pylori polypeptide selected from the group consisting of: SEQ ID NO:492 to SEQ ID NO:759, SEQ ID NO:761, SEQ ID NO:763, SEQ ID NO:765 to SEQ ID NO:818, SEQ ID NO:820 to SEQ ID NO:846, SEQ ID NO:848 to SEQ ID NO:896, SEQ ID NO:898 to SEQ ID NO:963, SEQ ID NO:966 to SEQ ID NO:982, SEQ ID NO:1037, SEQ ID NO:1038, SEQ ID NO:1041 to SEQ IDNO:1087, SEQ ID NO:1090, and SEQ ID NO:1296 to SEQ ID NO: 1298.

15. A vaccine composition for preventing or treating helicobacter pylori infection, comprising an effective dose of a purified helicobacter pylori polypeptide or a fragment thereof, wherein the helicobacter pylori polypeptide is selected from the group consisting of SEQ ID NO:492-SEQ ID NO:759, SEQ ID NO:761, SEQ ID NO:763, SEQ ID NO:765-SEQ ID NO:818, SEQ ID NO:820-SEQ ID NO:846, SEQ ID NO:848-SEQ ID NO:896, SEQ ID NO:898-SEQ ID NO:963, SEQ ID NO:966-SEQ ID NO:982, SEQ ID NO:1037, SEQ ID NO:1038, SEQ ID NO:1041-SEQ ID NO:1087, SEQ ID NO:1090, and SEQ ID NO:1296-SEQ ID NO: 1298.

16. The vaccine composition of claim 15, further comprising a pharmaceutically acceptable carrier.

17. The vaccine composition of claim 16, wherein the pharmaceutically acceptable carrier is an adjuvant.

18. A method of treating helicobacter pylori infection in a subject, comprising administering to the subject the vaccine composition of claim 15, thereby producing treatment for the helicobacter pylori infection.

19. The method of claim 18, wherein the treatment is a prophylactic treatment.

20. The method of claim 18, wherein the treatment is a therapeutic treatment.

21. An isolated nucleic acid comprising a nucleotide sequence encoding a helicobacter pylori cell envelope polypeptide or a fragment thereof, said nucleic acid being selected from the group consisting of SEQ ID NO 255, SEQ ID NO 263, SEQ ID NO 266, SEQ ID NO 277, SEQ ID NO 280, SEQ ID NO 285, SEQ ID NO 292, SEQ ID NO 294, SEQ ID NO 299, SEQ ID NO 311, SEQ ID NO 312, SEQ ID NO 313, SEQ ID NO 321, SEQ ID NO 327, SEQ ID NO 329, SEQ ID NO 331, SEQ ID NO 353, SEQ ID NO 364, SEQ ID NO 366, SEQ ID NO 368, SEQ ID NO 375, SEQ ID NO 384, SEQ ID NO 391, SEQ ID NO 392, SEQ ID NO 397, SEQ ID NO 398, SEQ ID NO 402, SEQ ID NO 404, SEQ ID NO 409, 410, 412, 427, 433, 452, 441, 444, 445, 449, 450, 452, 453, 466, 468, 469, 983, 989, 1008, 1011, 1014, 1015, 1029, 10231023, 1023, 1029, 1023, 259, 286, 326, 374, 399, 422, 454, 465, 1023, 1009, 1023, 10238, 1009, 326, 374, 399, 422, 454, 465, 998, 1009, 2, 1294, 1295, 319, 325, 425, 437, 438, 447, 448, 467, 996, 1027, 1031, 254, 352, 415, 1019, 381, 389, 1, 1012, 411, 407, 1017, 1, 1012, 354, 372, 400, 421, 463, 281, 988, 411, 407, 1017, 417, 430, 992, 1025, 477, 414, 253, 293, 334, 343, 418, 424 and 443.

22. The purified nucleic acid of claim 21, wherein said helicobacter pylori envelope polypeptide or fragment thereof is a helicobacter pylori outer membrane polypeptide or fragment thereof encoded by a nucleic acid selected from the group consisting of: SEQ ID NO 255, SEQ ID NO 263, SEQ ID NO 266, SEQ ID NO 277, SEQ ID NO 280, SEQ ID NO 285, SEQ ID NO 292, SEQ ID NO 294, SEQ ID NO 299, SEQ ID NO 311, SEQ ID NO 312, SEQ ID NO 313, SEQ ID NO 321, SEQ ID NO 327, SEQ ID NO 329, SEQ ID NO 331, SEQ ID NO 353, SEQ ID NO 364, SEQ ID NO 366, SEQ ID NO 368, SEQ ID NO 375, SEQ ID NO 384, SEQ ID NO 391, SEQ ID NO 392, SEQ ID NO 397, SEQ ID NO 398, SEQ ID NO 402, SEQ ID NO 404, SEQ ID NO 409, SEQ ID NO 410, SEQ ID NO 412, SEQ ID NO 427, SEQ ID NO 433, SEQ ID NO 434, SEQ ID NO 441, SEQ ID NO, 444, SEQ ID NO 445, SEQ ID NO 449, SEQ ID NO 450, SEQ ID NO 452, SEQ ID NO 453, SEQ ID NO 466, SEQ ID NO 468, SEQ ID NO 469, SEQ ID NO 983, SEQ ID NO 989, SEQ ID NO 1008, SEQ ID NO 1011, SEQ ID NO 1014, SEQ ID NO 1015,SEQ ID NO 1029, SEQ ID NO 1032, SEQ ID NO 259, SEQ ID NO 286, SEQ ID NO 326, SEQ ID NO 374, SEQ ID NO 399, SEQ ID NO 422, SEQ ID NO 454, SEQ ID NO 465, SEQ ID NO 998, SEQ ID NO 1023, SEQ ID NO 1294, SEQ ID NO 1009, SEQ ID NO 1295, SEQ ID NO 319, SEQ ID NO 325, SEQ ID NO 425, SEQ ID NO, 437, 438, 447, 448, 467, 996, 1027, 1031, 254, 352, 415, 1019, 381, 389, 1010 and 1012.

23. The purified nucleic acid of claim 22, wherein said helicobacter pylori outer membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof having a terminal phenylalanine residue encoded by a nucleic acid selected from the group consisting of: 255, 263, 266, 277, 280, 285, 292, 294, 299, 311, 312, 313, 321, 327, 329, 331, 353, 364, 366, 368, 375, 384, 391, 392, 409, 375, 384, 391, 392, 398, 402, 404, 409, 410, 412, 427, 433, 434, 441, 444, 445, 449, 450, 452, 453, 466, 468, 469, 983, 989, 1008, 1011, 1014, 1015, 1029 and 1032.

24. The purified nucleic acid of claim 22, wherein said helicobacter pylori outer membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof having a C-terminal tyrosine cluster encoded by a nucleic acid selected from the group consisting of: 286 SEQ ID NO, 326 SEQ ID NO, 374 SEQ ID NO, 399 SEQ ID NO, 422 SEQ ID NO, 454 SEQ ID NO, 465 SEQ ID NO, 998 SEQ ID NO, 1009 SEQ ID NO, 1023 SEQ ID NO, 1294 and 1295 SEQ ID NO.

25. The purified nucleic acid of claim 22, wherein said helicobacter pylori outer membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof having a terminal phenylalanine residue and a C-terminal tyrosine cluster encoded by a nucleic acid selected from the group consisting of: 319, 325, 425, 437, 438, 447, 448, 467, 996, 1027 and 1031.

26. The purified nucleic acid of claim 21, wherein said helicobacter pylori envelope polypeptide or fragment thereof is a helicobacter pylori inner membrane polypeptide or fragment thereof encoded by a nucleic acid selected from the group consisting of: 354, 372, 400, 421, 1022, 463, 281, 988, 411, 407, 1017, 290, 417, 430, 992 and 1025 amino acids.

27. The purified nucleic acid of claim 26, wherein said helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in outer membrane and cell wall synthesis encoded by a nucleic acid comprising the nucleotide sequence of SEQ ID No. 354.

28. The purified nucleic acid of claim 26, wherein said helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in energy conversion encoded by a nucleic acid selected from the group consisting of: 372, 400, 421 and 1022 SEQ ID NOs.

29. The purified nucleic acid of claim 26, wherein said helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in cofactor metabolism encoded by a nucleic acid comprising the nucleotide sequence of SEQ ID NO: 463.

30. The purified nucleic acid of claim 26, wherein said helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in secretion or adhesion encoded by a nucleic acid selected from the group consisting of SEQ ID NO. 281 and SEQ ID NO. 988.

31. The purified nucleic acid of claim 26, wherein said helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in trafficking encoded by a nucleic acid selected from the group consisting of SEQ ID NO 407 and SEQ ID NO 1017.

32. The purified nucleic acid of claim 21, wherein said helicobacter pylori cell envelope polypeptide or fragment thereof is a helicobacter pylori flagella polypeptide or fragment thereof encoded by a nucleic acid comprising the nucleotide sequence of SEQ ID NO: 477.

33. The purified nucleic acid of claim 21, wherein said helicobacter pylori cell envelope polypeptide or fragment thereof is a helicobacter pylori-transporting polypeptide or fragment thereof encoded by a nucleic acid comprising the nucleotide sequence of SEQ ID NO: 414.

34. A recombinant expression vector comprising the nucleic acid of claim 21 operably linked to a transcriptional regulatory element.

35. A cell comprising the recombinant expression vector of claim 34.

36. A method of producing a helicobacter pylori polypeptide, comprising culturing the cell of claim 35 under conditions permitting expression of the polypeptide.

37. An isolated nucleic acid comprising a nucleotide sequence encoding a helicobacter pylori secreting polypeptide or fragment thereof, said nucleic acid being selected from the group consisting of SEQ ID NO 355, SEQ ID NO 1006, SEQ ID NO 257, SEQ ID NO 258, SEQ ID NO 260,SEQ ID NO 261, SEQ ID NO 264, SEQ ID NO 265, SEQ ID NO 268, SEQ ID NO 270, SEQ ID NO 272, SEQ ID NO 274, SEQ ID NO 275, SEQ ID NO 276, SEQ ID NO 279, SEQ ID NO 283, SEQ ID NO 284, SEQ ID NO 287, SEQ ID NO 288, SEQ ID NO 289, SEQ ID NO 291, SEQ ID NO 295, SEQ ID NO 296, SEQ ID NO 297, SEQ ID NO 298, SEQ ID NO 300, SEQ ID NO 301, SEQ ID NO 302, SEQ ID NO, SEQ ID NO 303, 304, 305, 314, 315, 323, 338, 342, 348, 349, 356, 358, 359, 360, 361, 362, 363, 367, 370, 371, 373, 377, 378, 379, 380, 388, 390, 394, 396, 401, 403, 405, 378, 394, 395, 396, 401, 403, 396, 401, 403, 405, 408, 420, 426, 428, 429, 432, 439, 442, 451, 471, 478, 488, 987, 990, 991, 993, 1001, 1002, 1007, 1013, 1016, 1026.

38. The purified nucleic acid of claim 37, wherein said helicobacter pylori secreting polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in secretion and adhesion encoded by a nucleic acid selected from the group consisting of SEQ ID NO:355 and SEQ ID NO: 1006.

39. A recombinant expression vector comprising the nucleic acid of claim 38 operably linked to a transcriptional regulatory element.

40. A cell comprising the recombinant expression vector of claim 39.

41. A method of producing a helicobacter pylori polypeptide, comprising culturing the cell of claim 40 under conditions permitting expression of the polypeptide.

42. An isolated nucleic acid comprising a nucleotide sequence encoding a helicobacter pylori cytoplasmic polypeptide or a fragment thereof, said nucleic acid being selected from the group consisting of SEQ ID NO 470, SEQ ID NO 1033, SEQ ID NO 357, SEQ ID NO 457, SEQ ID NO 461, SEQ ID NO 1030, SEQ ID NO 345, SEQ ID NO 383, SEQ ID NO 387, SEQ ID NO 455, SEQ ID NO 1003, SEQ ID NO 351, SEQ ID NO 416, SEQ ID NO 278, SEQ ID NO 335, SEQ ID NO 346, SEQ ID NO 350, SEQ ID NO 419, SEQ ID NO 460, SEQ ID NO 472, SEQ ID NO 1000, SEQ ID NO 1004, SEQ ID NO 1020, SEQ ID NO 1293, SEQ ID NO 318, SEQ ID NO 322, SEQ ID NO 324, SEQ ID NO 330, SEQ ID NO 324, SEQ ID NO 330, SEQ ID NO, 347, 440, 446, 464, 490, 491, 995, 997, 1005 and 1028 amino acid sequences.

43. The purified nucleic acid of claim 42, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in energy conversion encoded by a nucleic acid selected from the group consisting of SEQ ID NO:470 and SEQ ID NO: 1033.

44. The purified nucleic acid of claim 42, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in amino acid metabolism and transport encoded by a nucleic acid selected from the group consisting of SEQ ID NO:357 and SEQ ID NO: 457.

45. The purified nucleic acid of claim 42, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in nucleotide metabolism and transport encoded by a nucleic acid selected from the group consisting of SEQ ID NO. 461 and SEQ ID NO. 1030.

46. The purified nucleic acid of claim 42, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in cofactor metabolism encoded by a nucleic acid selected from the group consistingof SEQ ID NO:345, SEQ ID NO:383, SEQ ID NO:387, SEQ ID NO:455, and SEQ ID NO: 1003.

47. The purified nucleic acid of claim 42, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in lipid metabolism encoded by a nucleic acid selected from the group consisting of SEQ ID NO. 351 and SEQ ID NO. 416.

48. The purified nucleic acid of claim 42, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in replication, transcription, recombination and repair of the genome encoded by a nucleic acid selected from the group consisting of SEQ ID NO 278, SEQ ID NO 335, SEQ ID NO 346, SEQ ID NO 350, SEQ ID NO 419, SEQ ID NO 460, SEQ ID NO 472, SEQ ID NO 1000, SEQ ID NO 1004, SEQ ID NO 1020 and SEQ ID NO 1293.

49. A recombinant expression vector comprising the nucleic acid of claim 42 operably linked to a transcriptional regulatory element.

50. A cell comprising the recombinant expression vector of claim 49.

51. A method of producing a helicobacter pylori polypeptide, comprising culturing the cell of claim 50 under conditions permitting expression of the polypeptide.

52. An isolated nucleic acid comprising a nucleotide sequence encoding a helicobacter pylori cellular polypeptide or a fragment thereof, said nucleic acid being selected from the group consisting of SEQ ID NO 256, SEQ ID NO 267, SEQ ID NO 282, SEQ ID NO 306, SEQ ID NO 307, SEQ ID NO 308, SEQ ID NO 309, SEQ ID NO 310, SEQ ID NO 316, SEQ ID NO 317, SEQ ID NO 332, SEQ ID NO 333, SEQ ID NO 336, SEQ ID NO 337, SEQ ID NO 339, SEQ ID NO 340, SEQ ID NO 341, SEQ ID NO 344, SEQ ID NO 369, SEQ ID NO 376, SEQ ID NO 382, SEQ ID NO 386, SEQ ID NO 423, SEQ ID NO 431, SEQ ID NO 435, SEQ ID NO 436, SEQ ID NO 458, SEQ ID NO 462, 475, 476, 479, 480, 481, 482, 483, 484, 485, 486, 487, 489, 984, 994, 1024 and 1036 SEQ ID NO.

53. A recombinant expression vector comprising the nucleic acid of claim 52 operably linked to a transcriptional regulatory element.

54. A cell comprising the recombinant expression vector of claim 53.

55. A method of producing a helicobacter pylori polypeptide, comprising culturing the cell of claim 54 under conditions permitting expression of the polypeptide.

56. A vaccine composition for preventing or treating helicobacter pylori infection, comprising an effective amount of the nucleic acid of claim 21.

57. The vaccine composition of claim 56, further comprising a pharmaceutically acceptable carrier.

58. The vaccine composition of claim 57, wherein the pharmaceutically acceptable carrier is an adjuvant.

59. A method of treating helicobacter pylori infection in a subject, comprising administering to the subject the vaccine composition of claim 56, thereby producing treatment for the helicobacter pylori infection.

60. The method of claim 59, whereinthe treatment is a prophylactic treatment.

61. The method of claim 59, wherein the treatment is a therapeutic treatment.

62. A vaccine composition for preventing or treating helicobacter pylori infection, comprising an effective amount of the nucleic acid of claim 37.

63. The vaccine composition of claim 62, further comprising a pharmaceutically acceptable carrier.

64. The vaccine composition of claim 63, wherein the pharmaceutically acceptable carrier is an adjuvant.

65. A method of treating helicobacter pylori infection in a subject, comprising administering to the subject the vaccine composition of claim 62, thereby producing treatment for the helicobacter pylori infection.

66. The method of claim 65, wherein the treatment is a prophylactic treatment.

67. The method of claim 65, wherein the treatment is a therapeutic treatment.

68. A vaccine composition for preventing or treating helicobacter pylori infection, comprising an effective amount of the nucleic acid of claim 42.

69. The vaccine composition of claim 68, further comprising a pharmaceutically acceptable carrier.

70. The vaccine composition of claim 69, wherein the pharmaceutically acceptable carrier is an adjuvant.

71. A method of treating helicobacter pylori infection in a subject, comprising administering to the subject the vaccine composition of claim 68, thereby producing treatment for the helicobacter pylori infection.

72. The method of claim 71, wherein the treatment is a prophylactic treatment.

73. The method of claim 71, wherein the treatment is a therapeutic treatment.

74. A vaccine composition for preventing or treating helicobacter pylori infection, comprising an effective amount of the nucleic acid of claim 52.

75. The vaccine composition of claim 74, further comprising a pharmaceutically acceptable carrier.

76. The vaccine composition of claim 75, wherein the pharmaceutically acceptable carrier is an adjuvant.

77. A method of treating helicobacter pylori infection in a subject, comprising administering to the subject the vaccine composition of claim 74, thereby producing treatment for the helicobacter pylori infection.

78. The method of claim 77, wherein the treatment is a prophylactic treatment.

79. The method of claim 77, wherein the treatment is a therapeutic treatment.

80. Purified H.pylori cell envelope polypeptide or a fragment thereof, wherein the polypeptide is selected fromthe group consisting of SEQ ID NO 746, SEQ ID NO 754, SEQ ID NO 757, SEQ ID NO 768, SEQ ID NO 771, SEQ ID NO 776, SEQ ID NO 783, SEQ ID NO 785, SEQ ID NO 790, SEQ ID NO 802, SEQ ID NO 803, SEQ ID NO 804, SEQ ID NO 812, SEQ ID NO 818, SEQ ID NO 820, SEQ ID NO 882, SEQ ID NO 844, SEQ ID NO 855, SEQ ID NO 857, SEQ ID NO 859, SEQ ID NO 866, SEQ ID NO 875, SEQ ID NO 882, SEQ ID NO 883, SEQ ID NO 888, SEQ ID NO 889, SEQ ID NO 893, SEQ ID NO 895, SEQ ID NO 900, SEQ ID NO 893, 901 SEQ ID NO, 903 SEQ ID NO, 918, 924, 925, 932, 935, 936, 940, 941, 943, 944, 957, 959, 960, 1037, 1043, 1062, 1065, 1068, 1069, 1083, 1086, 750, 777, 865, 890, 913, 945, 1069, 1083, 1086, 106890, 777, 817, 865, 890, 913, 945, 956, 1052, 1063, SEQ ID NO 1077, SEQ ID NO 1297, SEQ ID NO 1298, SEQ ID NO 810, SEQ ID NO 816, SEQ ID NO 916, SEQ ID NO 928, SEQ ID NO 929, SEQ ID NO 938, SEQ ID NO 939, SEQ ID NO 958, SEQ ID NO 1050, SEQ ID NO 1081, SEQ ID NO 1085, SEQ ID NO 745, SEQ ID NO 843, SEQ ID NO 9O6, SEQ ID NO 1073, SEQ ID NO 872, SEQ ID NO 880, SEQ ID NO 1064, SEQ ID NO 1066, SEQ ID NO 845, SEQ ID NO 863, SEQ ID NO 891, SEQ ID NO 912, SEQ ID NO 1076, SEQ ID NO 954, SEQ ID NO 772, SEQ ID NO 1042, SEQ ID NO 902, SEQ ID NO 898, 1071, 781, 908, 921, 1046, 1079, 968, 905, 744, 784, 825, 834, 909, 915 and 934.

81. The purified polypeptide of claim 80, wherein said H.pylori cell envelope polypeptide or fragment thereof is a H.pylori outer membrane polypeptide or fragment thereof selected from the group consisting of: 746 SEQ ID NO, 754 SEQ ID NO, 757 SEQ ID NO, 768 SEQ ID NO, 771 SEQ ID NO, 776 SEQ ID NO, 783 SEQ ID NO, 785 SEQ ID NO, 790 SEQ ID NO, 802 SEQ ID NO, 803 SEQ ID NO, 804 SEQ ID NO, 812 SEQ ID NO, 818 SEQ ID NO, 820 SEQ ID NO, 882 SEQ ID NO, 844 SEQ ID NO, 855 SEQ ID NO, 857 SEQ ID NO 859, 866 SEQ ID NO, 875 SEQ ID NO, 882 SEQ ID NO, 883 SEQ ID NO, 888 SEQ ID NO, 924 889 SEQ ID NO, 893 SEQ ID NO, 895 SEQ ID NO, 900 SEQ ID NO 901, 901 SEQID NO, 903 SEQ ID NO, 918, SEQ ID NO 918, SEQ ID NO 924, SEQ ID NO, 925, 932, 935, 957, 959, 960, 1037, 1043, 1062, 1065, 1068, 1069, 1083, 1, 750, 777, 945, 1068, 956, 1052, 1063, 1, 10625, 750, 777, 817, 865, 890, 913, 945, 956, 1052, 1063, 1067, 1071297, 1298, 810, 1063, 1067, 1077, 1297, 1298, 810, 816 SEQ ID NO, 916 SEQ ID NO, 928 SEQ ID NO, 929 SEQ ID NO, 938 SEQ ID NO, 939 SEQ ID NO, 958 SEQ ID NO, 1050 SEQ ID NO, 1081 SEQ ID NO 1085 SEQ ID NO 745, 843 SEQ ID NO, 906 SEQ ID NO, 1073 SEQ ID NO 872 SEQ ID NO 880, 1064 SEQ ID NO and 1066 SEQ ID NO.

82. The purified polypeptide of claim 81, wherein said helicobacter pylori outer membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof having a terminal phenylalanine residue selected from the group consisting of: 746 SEQ ID NO, 754 SEQ ID NO, 757 SEQ ID NO, 768 SEQ ID NO, 771 SEQ ID NO, 776 SEQ ID NO, 783 SEQ ID NO, 785 SEQ ID NO, 790 SEQ ID NO, 802 SEQ ID NO, 803 SEQ ID NO, 804 SEQ ID NO, 812 SEQ ID NO, 818 SEQ ID NO, 820 SEQ ID NO, 882 SEQ ID NO, 844 SEQ ID NO, 855 SEQ ID NO, 857 SEQ ID NO 859, 866 SEQ ID NO, 875 SEQ ID NO, 882 SEQ ID NO, 883 SEQ ID NO, 888 SEQ ID NO, 924 889 SEQ ID NO, 893 SEQ ID NO, 895 SEQ ID NO, 900 SEQ ID NO 901, 901 SEQ ID NO, 903 SEQ ID NO, 918, SEQ ID NO 918, SEQ ID NO 924, SEQ ID NO, 925, 932, 935, 936, 940, 941, 943, 944, 957, 959, 960, 1037, 1043, 1062, 1065, 1088, 1069, 1086.

83. The purified polypeptide of claim 81, wherein said helicobacter pylori outer membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof having a C-terminal tyrosine cluster selected from the group consisting of: 746 SEQ ID NO, 754 SEQ ID NO, 757 SEQ ID NO, 768 SEQ ID NO, 771 SEQ ID NO, 776 SEQ ID NO, 783 SEQ ID NO, 785 SEQ ID NO, 790 SEQ ID NO, 802 SEQ ID NO, 803 SEQ ID NO, 804 SEQ ID NO, 812SEQ ID NO, 818 SEQ ID NO, 820 SEQ ID NO, 882 SEQ ID NO, 844 SEQ ID NO, 855 SEQ ID NO, 857 SEQ ID NO 859, 866 SEQ ID NO, 875 SEQ ID NO, 882 SEQ ID NO, 883 SEQ ID NO, 888 SEQ ID NO, 924 889 SEQ ID NO, 893 SEQ ID NO, 895 SEQ ID NO, 900 SEQ ID NO 901, 901 SEQ ID NO, 903 SEQ ID NO, 918, SEQ ID NO 918, SEQ ID NO 924, SEQ ID NO, 925, 932, 935, 936, 940, 941, 943, 944, 957, 959, 960, 1037, 1043, 1062, 1065, 1088, 1069, 1083 and 1086.

84. The purified polypeptide of claim 81, wherein said H.pylori outer membrane polypeptide or fragment thereof is a H.pylori polypeptide or fragment thereof having a terminal phenylalanine residue and a C-terminal tyrosine cluster selected from the group consisting of: 810, 816, 916, 928, 929, 938, 939, 958, 1050, 1081 and 1085 SEQ ID NOs.

85. The purified polypeptide of claim 80, wherein said H.pylori cell envelope polypeptide or fragment thereof is a H.pylori inner membrane polypeptide or fragment thereof selected from the group consisting of: 845, 863, 891, 912, 1076, 954, 772, 1042, 902, 898, 1071, 781, 908, 921, 1046 and 1079 SEQ ID NO.

86. The purified polypeptide of claim 85, wherein said helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in outer membrane and cell wall synthesis comprising the amino acid sequence of SEQ ID NO: 845.

87. The purified polypeptide of claim 85, wherein said helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in energy conversion selected from the group consisting of: 863, 891, 912 and 1076.

88. The purified polypeptide of claim 85, wherein said helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in cofactor metabolism comprising the amino acid sequence of SEQ ID NO: 954.

89. The purified polypeptide of claim 85, wherein said helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in secretion or adhesion selected from the group consisting of SEQ ID NO 772 and SEQ ID NO 1042.

90. The purified polypeptide of claim 85, wherein said helicobacter pylori inner membrane polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in transport selected from the group consisting of SEQ ID NO:898 and SEQ ID NO: 1071.

91. The purified polypeptide of claim 80, wherein said helicobacter pylori cell envelope polypeptide or fragment thereof is a helicobacter pylori flagella polypeptide or fragment thereof comprising the amino acid sequence of SEQ ID NO: 968.

92. The purified polypeptide of claim 80, wherein said H.pylori cell envelope polypeptide or fragment thereof consists of a H.pylori-transporting polypeptide or fragment thereof comprising the amino acid sequence of SEQ ID NO: 905.

93. Purified H.pylori cellular polypeptide or a fragment thereof, wherein the polypeptide is selected from the group consisting of SEQ ID NO 747, 758, 773, 797, 798, 799, 800, 801, 807, 808, 823, 824, 827, 828, 830, 831, 832, 835, 860, 867, 922, 873, 877, 914, 922, 926, 92927, 927, 949, 953, 966, 967, 970,926, 927, 949, 953, 966, 970, 150, 7, 4, 971, 972, 973, 974, 975, 976, 977, 978, 980, 1038, 1048, 1078 and 1090, respectively.

94. Purified helicobacter pylori-secreting polypeptide or fragment thereof, wherein said polypeptide is selected from the group consisting of SEQ ID NO 846, SEQ ID NO 1060, SEQ ID NO 748, SEQ ID NO 749, SEQ ID NO 751, SEQ ID NO 752, SEQ ID NO 755, SEQ ID NO 756, SEQ ID NO 759, SEQ ID NO 761, SEQ ID NO 763, SEQ ID NO 765, SEQ ID NO 766, SEQ ID NO 767, SEQ ID NO 770, SEQ ID NO 774, SEQ ID NO 775, SEQ ID NO 778, SEQ ID NO 779, SEQ ID NO 780, SEQ ID NO 782, SEQ ID NO 786, SEQ ID NO 787, SEQ ID NO 788, SEQ ID NO 789, SEQ ID NO 791, SEQ ID NO 792, SEQ ID NO 793, SEQ ID NO 794, 795, 796, 805, 806, 814, 829, 833, 839, 840, 849, 850, 851, 852, 853, 854, 858, 861, 862, 864, 868, 869, 870, 871871, 871, 879, 885, 886, 887, 892, 894, 896, 899, 911, 899, SEQ ID NO. 917, SEQ ID NO. 919, SEQ ID NO. 920, SEQ ID NO. 923, SEQ ID NO. 930, SEQ ID NO. 933, SEQ ID NO. 942, SEQ ID NO. 962, SEQ ID NO. 969, SEQ ID NO. 979, SEQ ID NO. 1041, SEQ ID NO. 1044, SEQ ID NO. 1045, SEQ ID NO. 1047, SEQ ID NO. 1055, SEQ ID NO. 1056, SEQ ID NO. 1061, SEQ ID NO. 1067, SEQ ID NO. 1070, SEQ ID NO. 1072, SEQ ID NO. 1075 and SEQ ID NO. 1080.

95. The purified polypeptide of claim 94, wherein said helicobacter pylori secreting polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in secretion and adhesion selected from the group consisting of SEQ ID NO:846 and SEQ ID NO: 1060.

96. Purified cytoplasmic polypeptide of helicobacter pylori or a fragment thereof, wherein said polypeptide is selected from the group consisting of SEQ ID NO 961, SEQ ID NO 1087, SEQ ID NO 848, SEQ ID NO 948, SEQ ID NO 952, SEQ ID NO 1084, SEQ ID NO836, SEQ ID NO 874, SEQ ID NO 878, SEQ ID NO 946, SEQ ID NO 1057, SEQ ID NO 842, SEQ ID NO 907, SEQ ID NO 769, SEQ ID NO 826, SEQ ID NO 837, SEQ ID NO 841, SEQ ID NO 910, SEQ ID NO 951, SEQ ID NO 963, SEQ ID NO 1054, SEQ ID NO 1058, SEQ ID NO 1074, SEQ ID NO 1296, SEQ ID NO 809, SEQ ID NO 813, SEQ ID NO 815, SEQ ID NO 821, SEQ ID NO 838, SEQ ID NO 874, 931, 937, 955, 981, 982, 1049, 1051, 1059 and 1082.

97. The purified polypeptide of claim 96, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in energy transfer selected from the group consisting of SEQ ID NO:961 and SEQ ID NO: 1087.

98. The purified polypeptide of claim 96, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in amino acid metabolism and transport selected from the group consisting of SEQ ID NO:848 and SEQ ID NO: 948.

99. The purified polypeptide of claim 96, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in nucleotide metabolism and transport selected from the group consisting of SEQ ID NO 952 and SEQ ID NO 1084.

100. The purified polypeptide of claim 96, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide involved in cofactor metabolism selected from the group consisting of SEQ ID NO 836, SEQ ID NO 874, SEQ ID NO 878, SEQ ID NO 946, and SEQ ID NO 1057, or a fragment thereof.

101.The purified polypeptide of claim 96, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in lipid metabolism selected from the group consisting of SEQ ID NO 842 and SEQ ID NO 907.

102. The purified polypeptide of claim 96, wherein said helicobacter pylori cytoplasmic polypeptide or fragment thereof is a helicobacter pylori polypeptide or fragment thereof involved in replication, transcription, recombination and repair of the genome selected from the group consisting of SEQ ID NO 769, SEQ ID NO 826, SEQ ID NO 837, SEQ ID NO 841, SEQ ID NO 910, SEQ ID NO 951, SEQ ID NO 963, SEQ ID NO 1054, SEQ ID NO 1058, SEQ ID NO 1074, and SEQ ID NO 1296.

103. A vaccine composition for preventing or treating helicobacter pylori infection, comprising an effective dose of a helicobacter pylori polypeptide of claim 80.

104. The vaccine composition of claim 103, further comprising a pharmaceutically acceptable carrier.

105. The vaccine composition of claim 104, wherein the pharmaceutically acceptable carrier is an adjuvant.

106. A method of treating helicobacter pylori infection in a subject, comprising administering to the subject the vaccine composition of claim 103, thereby producing treatment for the helicobacter pylori infection.

107. The method of claim 106, wherein the treatment is a prophylactic treatment.

108. The method of claim 106, wherein the treatment is a therapeutic treatment.

109. A vaccine composition for preventing or treating helicobacter pylori infection, comprising an effective dose of a helicobacter pylori polypeptide of claim 93.

110. The vaccine composition of claim 109, further comprising a pharmaceutically acceptable carrier.

111. The vaccine composition of claim 110, wherein the pharmaceutically acceptable carrier is an adjuvant.

112. A method of treating a helicobacter pylori infection in a subject, comprising administering to the subject the vaccine composition of claim 109, thereby producing treatment for the helicobacter pylori infection.

113. The method of claim 112, wherein the treatment is a prophylactic treatment.

114. The method of claim 112, wherein the treatment is a therapeutic treatment.

115. A vaccine composition for preventing or treating helicobacter pylori infection, comprising an effective amount of a helicobacter pylori polypeptide of claim 94.

116. The vaccine composition of claim 115, further comprising a pharmaceutically acceptable carrier.

117. The vaccine composition of claim 116, wherein the pharmaceutically acceptable carrier is an adjuvant.

118. A method of treating a helicobacter pylori infection in a subject, comprising administering to the subject the vaccine composition of claim 115, thereby producing treatment for the helicobacter pylori infection.

119. The method of claim 118, wherein the treatment is a prophylactic treatment.

120. The method of claim 118, wherein the treatment is a therapeutic treatment.

121. A vaccine composition for preventing or treating helicobacter pylori infection, comprising an effective amount of the helicobacter pylori polypeptide of claim 96.

122. The vaccine composition of claim 121, further comprising a pharmaceutically acceptable carrier.

123. The vaccine composition of claim 122, wherein the pharmaceutically acceptable carrier is an adjuvant.

124. A method of treating helicobacter pylori infection in a subject, comprising administering to the subject the vaccine composition of claim 121, thereby producing treatment for the helicobacter pylori infection.

125. The method of claim 124, wherein the treatment is a prophylactic treatment.

126. The method of claim 124, wherein the treatment is a therapeutic treatment.

127. A method of detecting the presence of a helicobacter nucleic acid in a sample, comprising,

(a) contacting the sample with the nucleic acid of claim 21 under conditions whereby a hybridisation product is formed between the probe and the helicobacter nucleic acid in the sample; and are

(b) Detecting the hybridization product formed in step (a), wherein detection of the hybridization product indicates the presence of helicobacter nucleic acid in the sample.

128. A method of detecting the presence of a helicobacter nucleic acid in a sample, comprising,

(a) contacting the sample with the nucleic acid of claim 37 under conditions whereby a hybridisation product is formed between the probe and the helicobacter nucleic acid in the sample; and are

(b) Detecting the hybridization product formed in step (a), wherein detection of the hybridization product indicates the presence of helicobacter nucleic acid in the sample.

129. A method of detecting the presence of a helicobacter nucleic acid in a sample, comprising,

(a) contacting the sample with the nucleic acid of claim 42 under conditions whereby a hybridisation product is formed between the probe and the helicobacter nucleic acid in the sample; and are

(b) Detecting the hybridization product formed in step (a), wherein detection of the hybridization product indicates the presence of helicobacter nucleic acid in the sample.

130. A method of detecting the presence of a helicobacter nucleic acid in a sample, comprising,

(a) contacting the sample with the nucleic acid of claim 52 under conditions whereby hybridization products are formed between the probe and the helicobacter nucleic acid in the sample; and are

(b) Detecting the hybridization product formed in step (a), wherein detection of the hybridization product indicates the presence of helicobacter nucleic acid in the sample.

Images