SE0001988D0 - Novel polypeptides and use thereof - Google Patents
Novel polypeptides and use thereofInfo
- Publication number
- SE0001988D0 SE0001988D0 SE0001988A SE0001988A SE0001988D0 SE 0001988 D0 SE0001988 D0 SE 0001988D0 SE 0001988 A SE0001988 A SE 0001988A SE 0001988 A SE0001988 A SE 0001988A SE 0001988 D0 SE0001988 D0 SE 0001988D0
- Authority
- SE
- Sweden
- Prior art keywords
- polypeptides
- treatment
- disclosed
- novel polypeptides
- helicobacter
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 241000589989 Helicobacter Species 0.000 abstract 1
- 241000590002 Helicobacter pylori Species 0.000 abstract 1
- 102000010445 Lactoferrin Human genes 0.000 abstract 1
- 108010063045 Lactoferrin Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 229940037467 helicobacter pylori Drugs 0.000 abstract 1
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 abstract 1
- 229940078795 lactoferrin Drugs 0.000 abstract 1
- 235000021242 lactoferrin Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Lactoferrin binding polypeptides derived from Helicobacter pylori are disclosed. Said polypeptides comprise or consist of the polypeptide with SEQ. ID. No. 1, or a fragment thereof. Also nucleotide sequences encoding such polypeptides are disclosed, as well as use of such polypeptides in the treatment or prophylaxis of diseases caused by Helicobacter, and in the production of vaccines or pharmaceutical compositions for the prevention or treatment of diseases.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0001988A SE0001988D0 (en) | 2000-05-29 | 2000-05-29 | Novel polypeptides and use thereof |
| AU2001262839A AU2001262839A1 (en) | 2000-05-29 | 2001-05-25 | Lactoferrin polypeptides from h. pylori and vaccine compositions thereof |
| PCT/SE2001/001176 WO2001092336A1 (en) | 2000-05-29 | 2001-05-25 | Lactoferrin polypeptides from h. pylori and vaccine compositions thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0001988A SE0001988D0 (en) | 2000-05-29 | 2000-05-29 | Novel polypeptides and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE0001988D0 true SE0001988D0 (en) | 2000-05-29 |
Family
ID=20279868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0001988A SE0001988D0 (en) | 2000-05-29 | 2000-05-29 | Novel polypeptides and use thereof |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU2001262839A1 (en) |
| SE (1) | SE0001988D0 (en) |
| WO (1) | WO2001092336A1 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6086893A (en) * | 1995-10-09 | 2000-07-11 | Pasteur Merieux Serums & Vaccins | Helicobacter lactoferrin receptor |
| JP2000501621A (en) * | 1996-03-29 | 2000-02-15 | アストラ・アクテイエボラグ | Nucleic acid and amino acid sequences related to Helicobacter pylori and vaccine compositions thereof |
| AU756010B2 (en) * | 1997-04-01 | 2003-01-02 | Human Genome Sciences, Inc. | Identification of polynucleotides encoding novel helicobacter polypeptides in the helicobacter genome |
| WO1999021959A2 (en) * | 1997-10-28 | 1999-05-06 | Genome Therapeutics Corporation | Helicobacter pylori vaccine formulations |
-
2000
- 2000-05-29 SE SE0001988A patent/SE0001988D0/en unknown
-
2001
- 2001-05-25 WO PCT/SE2001/001176 patent/WO2001092336A1/en active Application Filing
- 2001-05-25 AU AU2001262839A patent/AU2001262839A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001262839A1 (en) | 2001-12-11 |
| WO2001092336A1 (en) | 2001-12-06 |
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