CN1219537C - Chinese medicine for treating leucocythemia and its preparation method and application. - Google Patents

Chinese medicine for treating leucocythemia and its preparation method and application. Download PDF

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CN1219537C
CN1219537C CNB031264212A CN03126421A CN1219537C CN 1219537 C CN1219537 C CN 1219537C CN B031264212 A CNB031264212 A CN B031264212A CN 03126421 A CN03126421 A CN 03126421A CN 1219537 C CN1219537 C CN 1219537C
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CN1493327A (en
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李维庆
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Abstract

The present invention relates to a traditional Chinese medicament for treating leucocythemia and a preparation method and an application thereof. The present invention aims to solve the defects of no obvious treatment effect and toxic side effect of the existing medicament. The present invention is prepared by the medicaments of the following raw materials of largehead atractylodesrhizome, bugleweed, pulsatilla chinensis, pinellia tuber, milk vetch, angelica, stir-baking fructus hordei germinatus et craminatus et massa fer-mentata medicinalis, turtle shells, peach kernel, safflower, liquorice roots, donkey-hide glue, Chinese rose flower, madagascar periwinkle herb, black medic herb, assam crotalaria leaves, common four-o'clock seeds, gold pot grass, frankincense, myrrh, chicken-blood teng and catclaw buttercup roots. The present invention is used for treating acute lymphocyte, sub-performance lymphocyte, myelocyte, chronic granulocyte avian leukosis, dizziness, asthenia, sour pain for a whole body, lumbago, tinnitus, stomachache and frequent diarrhea diseases. The present invention has the advantages of no toxic side effect, obvious treatment effect and high cure rate.

Description

Treat leukemic Chinese medicine and preparation method thereof
Technical field
The present invention relates to leukemic treatment technology, particularly relate to leukemic Chinese medicine of a kind of treatment and preparation method thereof.
Background technology
For " leukemia ", be the disease of extremely World Focusing.The modern medicine science is many with the treatment of bone marrow transplantation method for " leukemia "; For the traditional Chinese medical science, history does not stay record, does not have what good way yet.
" leukemia " has four kinds according to Western medicine diagnose: acute lymphoblastic, Asia property lymphocyte, myelocyte and slow granulocyte.Generally, Western medicine diagnose mainly by chemical examination, wear, and comes the number of diagnosis cell by bone, except that the diagnostic method of doctor trained in Western medicine, also has the diagnostic method of the traditional Chinese medical science.
Each organ of human body, each cun skin, each root hair all must provide oxygen and nutrient by blood, so blood quality concerns the health in our everyone all one's life.When we look back " leukemia " all one's life that the patient experienced, we are surprised to find them often with following logical development relation.Initial stage: headache, giddy, heating, low grade fever, absent minded, fatiguability: mid-term: continuous firing ability drop, drowsiness, spleen enlargement, abdominal distention, diet go down or the like.For " leukemia " disease, each medical circle all has research method separately at world wide, and each method all has different point of care.No matter but be the traditional Chinese medical science also doctor trained in Western medicine all have defective, promptly often toxic and side effects is big for Western medicine, existing Chinese medicine then curative effect is not remarkable.
Summary of the invention
The objective of the invention is to overcome the above-mentioned defective of prior art, provide a kind of evident in efficacy, and the leukemic Chinese medicine of the treatment that has no side effect.The present invention also aims to provide its preparation method.
For the ease of understanding the technical scheme of Chinese medicine of the present invention, now the inventor is described below the understanding and the new discovery of leukemia pathology:
The inventor thinks that " leukemia " generally caused by paratyphoid fever, is the spleen enlargement of chronic congestion and the adverse consequences that causes.Why diagnose like this? because 98% spleen enlargement among " leukemia " patient, have greater than 10m, have greater than 20m, about the traditional Chinese medical science, spleen is " central authorities' soil ", and its effect is exactly to help taste digestion, its function in addition: hemopoietic function is arranged, also have the function of overanxious impurity.
" interpromoting relation in five elements, the restriction or checking relation in five elements " said in the theory of yin-yang and five elements (metal, wood, water, fire and earth) about the traditional Chinese medical science.Because " soil is weak ", gram wood, " wood " that five-elements theory is said is exactly the wording of " liver ", and this just is called " Tu Kemu ".Just produced disease so " building restriction or checking relation in five elements " time, spleen transport to the thing of liver promptly " all foreign material " do not have overanxious intact.At this moment wait, produced impurity in the hepatic portal vein, flow to the blood that whole body needs, at first, through heart, heart gives whole body again, and like this, the time one is long, just can reflect the disease of disease.So, what is a cancer? be exactly in the body of the person in all caused poison of foreign material.Through the research diagnosis, patient according to the theory " leukemia " of the traditional Chinese medical science, the 90%th, from the disease that affection of exogenous wind-cold causes, " leukemia " just found in the morbidity of Most patients upper respiratory tract infection and lung disease later on, small number of patients out of the ordinary arranged because of causing through the dizzy disease anemia of long-chord.Generally " leukemia " is person inner blood edema caused by disorder of QI and the tumor that forms.But can not say fully like this that only a few disease out of the ordinary is come by congenital, 98% be to bring the day after tomorrow.No matter be what is former thereby cause, concentrate on crucial points, exactly based on " spleen, liver ", be secondary with the kidney, handy blood circulation promoting and blood stasis dispelling in the time of treatment, QI invigorating is enriched blood, and the replenishing essence QI invigorating is with the painful abdominal mass blood stasis dispelling softening the hard mass that disappears, blood stasis dispelling spleen invigorating, stomach, nourishing the liver, the method for cooling blood for hemostasis.
For achieving the above object, the present invention's crude drug for the treatment of leukemic Chinese medicine comprises:
The Rhizoma Atractylodis Macrocephalae, Haematitum, Spica Prunellae, the Radix Pulsatillae, the Rhizoma Pinelliae, the Radix Astragali, Radix Angelicae Sinensis, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Carapax Trionycis, Semen Persicae, Flos Carthami, Radix Glycyrrhizae, Colla Corii Asini, Flos Rosae Chinensis, Herba Catharanthi Rosei, Herba Medicaginis Lupulinae, Caulis et Folium Crotalariae Assamicae, Semen mirabilis, Jin Pencao, Olibanum, Myrrha, Caulis Spatholobi, Radix Ranunculi Ternati.JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) is the food that is good for the stomach of parch, natural food additive or the succedaneum of food.
The composition principle of medicine of the present invention is: the Radix Astragali, and the QI invigorating of regulating the flow of vital energy QI and blood regulating: the Rhizoma Atractylodis Macrocephalae, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), strengthening the spleen and stomach helps digestion: Flos Carthami, the Semen Persicae blood circulation promoting and blood stasis dispelling is for the patient that lump is arranged in splenomegaly and the abdomen power of circulation of qi promoting fortune blood then.Spica Prunellae, Haematitum, the Rhizoma Pinelliae, the Radix Pulsatillae has the function of conditioning blood, can transfer and can mend, and the effect of conditioning is that a left side makes.Herba Catharanthi Rosei, Herba Medicaginis Lupulinae, Caulis et Folium Crotalariae Assamicae is when being classified as can decide monarch's effect of monarch: Spica Prunellae, Haematitum, the Rhizoma Pinelliae, the Rhizoma Atractylodis Macrocephalae, Semen Persicae, Flos Carthami are that the right side makes: JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Radix Glycyrrhizae are minister, can mobilize troop, can not extremely use with minister, the monarch and his subjects are core with monarch, and left and right sides special envoy can be with usefulness, with changing.For the leukemia that lonizing radiation cause, then reuse Caulis Spatholobi.
As optimization, its crude drug also comprises: Radix Pseudostellariae or Radix Codonopsis, Pseudobulbus Cremastrae Seu Pleiones, Indigo Naturalis, Realgar.Radix Pseudostellariae or Radix Codonopsis decide monarch's effect and assistant's gas QI invigorating QI and blood regulating.The deficiency of vital energy deducts crown prince and participates in Radix Codonopsis or Radix Ginseng; Liver, splenomegaly are then reused Semen Persicae, Flos Carthami etc.Here Radix Ginseng can exchange with Radix Pseudostellariae or Radix Codonopsis, and promptly Radix Ginseng also should be protected.
As optimization, the weight proportion of each crude drug is: Rhizoma Atractylodis Macrocephalae 7-14, Haematitum 25-36, Spica Prunellae 11-18, Radix Pulsatillae 8-13, Rhizoma Pinelliae 7-14, Radix Astragali 24-36, Radix Angelicae Sinensis 12-18, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 16-24, Carapax Trionycis 21-28, Semen Persicae 7-13, Flos Carthami 12-17, Radix Glycyrrhizae 8,12, Colla Corii Asini 12-17, Flos Rosae Chinensis 17-24, Herba Catharanthi Rosei 26--35, Herba Medicaginis Lupulinae 25-35, Caulis et Folium Crotalariae Assamicae 25-35, Semen mirabilis 17-24, golden basin grass 7-13, Olibanum 8-12, Myrrha 8-12, Caulis Spatholobi 7-13, Radix Ranunculi Ternati 12-17.
As optimization, the weight proportion of each crude drug is: Radix Pseudostellariae or Radix Ginseng 6-13, Rhizoma Atractylodis Macrocephalae 7-14, Haematitum 25-36, Spica Prunellae 11-18, Radix Pulsatillae 8-13, Rhizoma Pinelliae 7-14, Radix Astragali 24-36, Radix Angelicae Sinensis 12-18, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 16-24, Carapax Trionycis 21-28, Semen Persicae 7-13, Flos Carthami 12-17, Radix Glycyrrhizae 8-12, Colla Corii Asini 12-17, Flos Rosae Chinensis 17-24, Herba Catharanthi Rosei 26-35, Herba Medicaginis Lupulinae 25-35, Caulis et Folium Crotalariae Assamicae 25-35, Semen mirabilis 17-24, gold basin grass 7-13, Olibanum 8-12, Myrrha 8-12, Caulis Spatholobi 7-13, Radix Ranunculi Ternati 12-17, Pseudobulbus Cremastrae Seu Pleiones 10-18, Indigo Naturalis 4-8, Realgar 2-5.
As optimization, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) is the mixture of Fructus Crataegi, Massa Medicata Fermentata and the Fructus Hordei Germinatus of parch.The prescription of this crude drug is to get the strengthening the spleen and stomach and the food digesting action of Fructus Crataegi, Massa Medicata Fermentata and the Fructus Hordei Germinatus mixture of parch.As most preferred technical scheme, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) is mixed and the eleventh of the twelve Earthly Branches by Fructus Crataegi, Massa Medicata Fermentata and the Fructus Hordei Germinatus of the equal weight ratio of parch.
It is the fried one-tenth decoction of water that the present invention treats leukemic preparation method of Chinese medicine.
As optimization, when fried: with high heat earlier, after use slow fire.The method of using with of intense fire and slow fire is better to extract the pharmacology composition in the crude drug.
As optimization, the part by weight of crude drug gross weight and water is 2.5-5; The ratio of fried time of intense fire and fried time of slow fire is 1.2-4.The design of this technical scheme is better to guarantee the drug effect of decoction.
As optimization, fried time 〉=25 of slow fire minute, fried time 〉=10 of intense fire minute; Fry in shallow oil to the decoction amount be the crude drug gross weight 1.5-2.5 doubly.The technical scheme of this fried medicine all is in order fully to guarantee the performance of the crude drug efficacy of a drug.
The application of medicine of the present invention is can also be used to prepare powder, pill, tablet and oral liquid except that being used to make the decoction.Certainly medicine of the present invention can also be made and be used for the treatment of giddy, weak, systemic pain, lumbago, tinnitus, stomachache and the frequent medicine of the various dosage forms of diarrhoeal diseases.
The usage of medicine of the present invention: decoction, every day potion, divide three times oral.Take about 200 milliliters at every turn.Can certainly divide three decoctions.
Prove through clinical practice: medicine of the present invention has significant curative effect for leukemia treating.Inventor's treatment " leukemia " that began one's study in 9 years, clinical effectiveness proof cure rate reaches more than 80%.Now exemplify an example wherein: in 2002, the i.e. cadre of the Golmud City city Women's Federation of a patient that the hospitalize of Tianjin hematology is invalid is arranged, Yuan Mei is a young cadre, just 28 years old she in this year, September 2002, check out " leukemia ", invalid in this city people hospitalize, change the province the People's Hospital, province fails to respond to any medical treatment the People's Hospital, change Tianjin hematology, section hospital is at Tianjin hematology hospitalize three wheat harvesting periods, leukocyte is pressed in more than 39000 and does not fall, introduce and listen friend's legend through the patient, return the treatment of here, Golmud City, now cure.
After adopting technique scheme, the present invention treats leukemic Chinese medicine and is applicable to acute lymphoblastic, Asia property lymphocyte, myelocyte and chronic myeloid leukemia, and dizzy, weak, systemic pain, lumbago, tinnitus, stomachache, frequent determined curative effect such as diarrhoeal diseases, and life-time service has no adverse reaction.Be used for the treatment of the leukaemic and have and have no side effect, evident in efficacy, the advantage that cure rate is high.
The specific embodiment
Below in conjunction with instantiation, be described in further detail:
The weight proportion that the present invention treats the crude drug of leukemic Chinese medicine is: (unit of weight gram)
One, the Rhizoma Atractylodis Macrocephalae 7,10,14, Haematitum 25,30,36, Spica Prunellae 11,15,18, the Radix Pulsatillae 8,10,13, the Rhizoma Pinelliae 7,10,14, the Radix Astragali 24,30,36, Radix Angelicae Sinensis 12,15,18, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 16,20,24, Carapax Trionycis 21,25,28, Semen Persicae 7,10,13, Flos Carthami 12,15,17, Radix Glycyrrhizae 8,10,12, Colla Corii Asini 12,15,17, Flos Rosae Chinensis 17,20,24, Herba Catharanthi Rosei 26,30,35, Herba Medicaginis Lupulinae 25,30,35, Caulis et Folium Crotalariae Assamicae 25,30,35, Semen mirabilis 17, add, 24, gold basin grass 7,10,13, Olibanum 8,10,12, Myrrha 8,10,12, Caulis Spatholobi 7,10,13, Radix Ranunculi Ternati 12,15,17.
Two, Radix Pseudostellariae or Radix Codonopsis 6,10,13, the Rhizoma Atractylodis Macrocephalae 7,10,14, Haematitum 25,30,36, Spica Prunellae 11,15,18, the Radix Pulsatillae 8,10,13, the Rhizoma Pinelliae 7,10,14; The Radix Astragali 4,39,36, Radix Angelicae Sinensis 12,15,18, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 16,20,24, Carapax Trionycis 21,25,28, Semen Persicae 7,10,13, Flos Carthami 12,15,17, Radix Glycyrrhizae 8,10,12, Colla Corii Asini 12,15,17, Flos Rosae Chinensis 17,20,24, Herba Catharanthi Rosei 26,30,35, Herba Medicaginis Lupulinae 25,30,35, Caulis et Folium Crotalariae Assamicae 25,30,35, Semen mirabilis 17,20,24, golden basin grass 7,10,13, Olibanum 8,10,12, Myrrha 8,10,12, Caulis Spatholobi 7,10,13, Radix Ranunculi Ternati 12,15,17, Pseudobulbus Cremastrae Seu Pleiones 10,15,18, Indigo Naturalis 4,5,8, Realgar 2,3,5.
It is the fried one-tenth decoction of water that the present invention treats leukemic preparation method of Chinese medicine.The part by weight of its crude drug gross weight and water is 2.5-5.When fried: with high heat earlier, after use slow fire.The ratio of fried time of intense fire and fried time of slow fire is 1: 2-4.Fried time 〉=10 of intense fire minute, fried time 〉=25 of slow fire minute; Fry in shallow oil to the decoction amount be the crude drug gross weight 1.5-2.5 doubly.
The application of medicine of the present invention is can also be used to prepare powder, pill, tablet and oral liquid except that being used to make the decoction.

Claims (6)

1, the leukemic Chinese medicine of a kind of treatment is characterized in that it is that following column weight amount proportion raw material is made: Rhizoma Atractylodis Macrocephalae 7-14, Haematitum 25-36, Spica Prunellae 11-18, Radix Pulsatillae 8-13, Rhizoma Pinelliae 7-14, Radix Astragali 24-36, Radix Angelicae Sinensis 12-18, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 16-24, Carapax Trionycis 21-28, Semen Persicae 7-13, Flos Carthami 12-17, Radix Glycyrrhizae 8-12, Colla Corii Asini 12-17, Flos Rosae Chinensis 17-24, Herba Catharanthi Rosei 26-35, Herba Medicaginis Lupulinae 25-35, Caulis et Folium Crotalariae Assamicae 25-35, Semen mirabilis 17-24, golden basin grass 7-13, Olibanum 8-12, Myrrha 8-12, Caulis Spatholobi 7-13, Radix Ranunculi Ternati 12-17.
2, the leukemic Chinese medicine of a kind of treatment is characterized in that it is that following column weight amount proportion raw material is made: Radix Pseudostellariae or Radix Codonopsis 6-13, Rhizoma Atractylodis Macrocephalae 7-14, Haematitum 25-36, Spica Prunellae 11-18, Radix Pulsatillae 8-13, Rhizoma Pinelliae 7-14, Radix Astragali 24-36, Radix Angelicae Sinensis 12-18, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 16-24, Carapax Trionycis 21-28, Semen Persicae 7-13, Flos Carthami 12-17, Radix Glycyrrhizae 8-12, Colla Corii Asini 12-17, Flos Rosae Chinensis 17-24, Herba Catharanthi Rosei 26-35, Herba Medicaginis Lupulinae 25-35, Caulis et Folium Crotalariae Assamicae 25-35, Semen mirabilis 17-24, gold basin grass 7-13, Olibanum 8-12, Myrrha 8-12, Caulis Spatholobi 7-13, Radix Ranunculi Ternati 12-17, Pseudobulbus Cremastrae Seu Pleiones 10-18, Indigo Naturalis 4-8, Realgar 2-5.
3, a kind of claim 1 or 2 described preparation method of Chinese medicine is characterized in that the fried one-tenth decoction of water.
4, preparation method according to claim 3 is characterized in that when fried: with high heat earlier, after use slow fire.
5, preparation method according to claim 4, the part by weight that it is characterized in that crude drug gross weight and water is 2.5-5; The ratio of fried time of intense fire and fried time of slow fire is 1: 2-4.
6, preparation method according to claim 5 is characterized in that fried time 〉=25 of slow fire minute, fried time 〉=10 of intense fire minute; Fry in shallow oil to the decoction amount be the crude drug gross weight 1.5-2.5 doubly.
CNB031264212A 2003-09-28 2003-09-28 Chinese medicine for treating leucocythemia and its preparation method and application. Expired - Fee Related CN1219537C (en)

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Publication number Priority date Publication date Assignee Title
CN101584802B (en) * 2009-06-17 2011-06-08 李宗宪 Chinese medicinal capsule for treating malignant lymphoma
CN109589389A (en) * 2018-12-18 2019-04-09 李天基 A kind of drug and preparation method thereof for treating leukaemia

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