CN1215854C - Medicine for treating gynaecology and obstetrics disease and preparation method - Google Patents
Medicine for treating gynaecology and obstetrics disease and preparation method Download PDFInfo
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Abstract
The present invention relates to medicine for treating various kinds of gynecopathy and a preparation method thereof. The medicine is prepared by processing Chinese herbal medicine comprising saffron crocus, notoginseng, prepared Radix Angelicae Sinensis with yellow rice spirits, prepared Rhizoma Cyperi with vinegar, prepared rhizoma coridalis with vinegar, costus roots, raw peach seed, prepared Rhizoma Chuan Xiong with yellow rice spirits and stir-frying bupleurum root. The medicine has the main function for activating blood circulation to dissipate blood stasis, has the auxiliary functions for nourishing the blood and harmonizing the blood, and has the assistant functions for dispersing the stasis, dispelling the nodule, soothing the liver and regulating vital energy. The preparation method is formed by applying the Chinese medicine compounding modes of the sovereign medicine, the minister medicine, the adjuvant medicine and the envoy medicine. The medicine can adopt different medicinal ushers to treat different diseases with the same method according to different symptoms and different clinical situations of patients. The medicine is ideal medicine for treating various kinds of gynecopathy, particularly for treating dysmenorrhoea due to the qi stagnation and the blood stasis of females, and has the advantage of obvious effect. By the observation of clinical curative effects, the total effective rate of the medicine reaches 96%.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of obstetrical and gynecological disease, being specifically related to a kind of is the medicine of the treatment obstetrical and gynecological disease of making of raw material with the Chinese herbal medicine.
Background technology
Obstetrical and gynecological disease, as its name suggests, i.e. the distinctive disease of women, comprising menopathy, leukorrheal diseases, pregnancy disease, puerperal disease and miscellaneous gynecological diseases, to include disease comparatively extensive because of it, so be referred to as gynecologic and obstetric disease herein.
The women innately has through special physiological functions such as, pregnant, product, breasts, add again the human body natural endowment difference and the day after tomorrow condition effect, such as factors such as environment, age, diet, nutrition, exhaustion due to sexual indulgence, fecund and the women susceptibility to disease factor, this has just caused the variation of obstetrical and gynecological disease and complicated.If lack self health consciousness and common health care knowledge in daily life again, tend to make them among quietly can not help, grow various obstetrical and gynecological diseases.In addition, China women is fettered by traditional feudal ethical code for a long time, sternly avoids a lot of: some women suffers from a disease, and frighteningly knows that the back influences love and marriage, and the misery of bearing disease patiently dare not be sayed and control; Some women is too shy to speak out because of the slight illness at " secret " position, does not slowly go to seek medical advice, and the state of an illness is progressively worsened.All this kind, be cause obstetrical and gynecological disease sickness rate height, painful big, control thorny key point.
Summary of the invention
The purpose of this invention is to provide a kind of under the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs principle of the traditional Chinese medical science " treating the same disease with different methods ", " treating different diseases with the same therapeutic principle ", closely center on the pathogeny of obstetrical and gynecological disease ubiquity " qi depression to blood stasis ", adopt different guiding drugs, be equipped with blood circulation promoting and blood stasis dispelling, depressed liver-energy dispersing and QI regulating, nourish blood and blood among the medicine and preparation method thereof of the various obstetrical and gynecological diseases of treatment made of medical herbs.
The present invention adopts following scheme to realize, the medicine of treatment obstetrical and gynecological disease is through the resulting concentrated medicated powder of active ingredient in the concentration extraction Chinese herbal medicine crude drug, it is characterized in that it is to be made by following materials of weight proportions:
1 part-30 parts of 1 portion of-30 portions of Radix Notoginsengs of Stigma Croci
1 part-30 parts of 2 parts of-60 parts of Rhizoma Cyperi (processed with vinegar) of Radix Angelicae Sinensis (processed with wine)
1 part-30 parts of 1 portion of-30 portions of Radix Aucklandiae (Radix Vladimiriae) of vinegar Rhizoma Corydalis
1 part-30 parts of 1 part of-30 parts of prepared RHIZOMA CHUAN XIONG with yellow rice wine of raw peach kernel
Process 1 part-30 parts of Radix Bupleuri.
The present invention treats the medicine of obstetrical and gynecological disease, it is characterized in that: made by following materials of weight proportions:
30 parts of 60 parts of Rhizoma Cyperi (processed with vinegar) of 30 parts of Radix Angelicae Sinensis (processed with wine) of 30 portions of Radix Notoginsengs of Stigma Croci
30 parts of prepared RHIZOMA CHUAN XIONG with yellow rice wine of 30 parts of raw peach kernels of 30 portions of Radix Aucklandiae (Radix Vladimiriae) of vinegar Rhizoma Corydalis are processed 30 parts of Radix Bupleuri for 30 parts.
The present invention treats the medicine of obstetrical and gynecological disease, is through the resulting concentrated medicated powder of active ingredient in the concentration extraction herbal raw material, it is characterized in that: made by following materials of weight proportions:
10 parts of 10 portions of Radix Notoginsengs of Stigma Croci
10 parts of 20 parts of Rhizoma Cyperi (processed with vinegar) of Radix Angelicae Sinensis (processed with wine)
10 parts of 10 portions of Radix Aucklandiae (Radix Vladimiriae) of vinegar Rhizoma Corydalis
10 parts of 10 parts of prepared RHIZOMA CHUAN XIONG with yellow rice wine of raw peach kernel
Process 10 parts of Radix Bupleuri
Above-mentioned each component is made medicine production method of the present invention, it is characterized in that:
(1). choose Radix Angelicae Sinensis (processed with wine), Rhizoma Cyperi (processed with vinegar), vinegar Rhizoma Corydalis, Radix Aucklandiae (Radix Vladimiriae), raw peach kernel, prepared RHIZOMA CHUAN XIONG with yellow rice wine, process water logging bubble 12-36 hour that Radix Bupleuri seven flavor Chinese medicines add 5-15 times of dose according to weight proportion;
(2). decoct three times:, leach behind the medicinal liquid stand-by for the first time with slow fire boiling 1.5-4.5 hour; The decocting that adds for the second time 3.5-10.5 times of dose boiled 1-3 hour, leached behind the medicinal liquid stand-by; The decocting that adds 2.5-7.5 times of dose for the third time boiled 0.5-1.5 hour, leached behind the medicinal liquid stand-by;
(3). merge three times decocting liquid, filter;
(4). be concentrated into the thick paste of relative density, stand-by.
(5). it is stand-by according to choosing Stigma Croci, Radix Notoginseng two flavor Chinese medicines in the weight proportion, to choose and wear into fine powder behind the clean impurity, sieve.
(6). Chinese medicines such as above-mentioned Radix Angelicae Sinensis (processed with wine) are concentrated Chinese medicine fine powder mix homogeneously such as thick paste and Stigma Croci;
(7). cold drying;
(8). wear into fine powder, sieve;
(9). divide encapsulated;
(10). concentrate with the sterilization of cobalt 60 x ray irradiation xs the sealing back.
The present invention is through clinical observation and checking repeatedly, while is in conjunction with the pathological state of women's ubiquity " blood is often not enough; gas is often had a surplus ", and follow " gas with logical be usefulness; blood is based on that harmony is what matters " traditional view, utilization traditional Chinese medical science monarch, minister, the compatibility form of helping, making are selected the pure natural rare Chinese medicine side of being combined into " blood circulation promoting and blood stasis dispelling, depressed liver-energy dispersing and QI regulating, nourish blood and blood ".Because the patient has its different predisposing factorss and individual specificity, its clinical symptoms varies with each individual, and cold, the heat that is showed, phenomenon such as empty, real also are not quite similar.So,, add many guiding drugs " treating different diseases with the same therapeutic principle ", " remedying defects and rectifying errors " again in addition according to the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs principle of the traditional Chinese medical science " treating the same disease with different methods ", " treating different diseases with the same therapeutic principle " and different clinical syndromes.Having demonstrated fully the present invention is under the preceding topic of the traditional Chinese medical science " organic conception ", closely the pathogeny something lost side around obstetrical and gynecological disease ubiquity " qi depression to blood stasis " sends medicine, especially adopt different guiding drugs to control different diseases, widened effect of the present invention and indication category undoubtedly.
The present invention mainly is made up of nine flavor rare Chinese medicines such as Stigma Croci, Radix Notoginseng, Radix Angelicae Sinensis (processed with wine).The Stigma Croci nature and flavor are sweet flat in the side, are good at promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain.Though it and Flos Carthami functional similarity, its efficacy of a drug is stronger, and the merit of dispersing stagnation and relieving accumulation of pathogens, removing pathogenic heat from blood and toxic substance from the body is arranged again, thus in we with being main (monarch) medicine; Radix Notoginseng hemostasis dissipating blood stasis, subduing swelling and relieving pain, because of the stasis of blood is not stayed in its hemostasis, dissipating blood stasis and just not hindering, so " Records of Tradition Chinese and Western Medicine in Combination " meaning Radix Notoginseng " be its kind blood stasis dispelling blood; so the kind women sub-mass in the abdomen, menses controlled is obstructed. blood stasis dispelling blood and do not hinder fresh blood, permit to be the quality goods for the treatment of blood disorders ".Radix Angelicae Sinensis (processed with wine) tonifying blood and regulating menstruation, promoting blood circulation and stopping pain are the panacea for gynecological, and two medicines share and are minister, all diseases in married woman's puerperal that auxiliary principal agent Stigma Croci treatment causes because of " syndrome of blood stasis ", both can strengthen the merit of the analgesic therapy of invigorating blood circulation, promoting tissue regeneration by removing blood stasis, and can allow cloudy blood support again, irritability must with; And because of women's natural endowment " gas is often had a surplus ", the easiest disease of bringing out depression of liver-QI, " yet product converge with essence will " call again Stigma Croci can " the chest stuffiness relieving diaphragm, appetizing feed; for a long time clothes grow down unit, improving healthy complexion, still can constraint eliminating and menstruation regulating ", help with Rhizoma Cyperi (processed with vinegar), process group's depressed liver-energy dispersing and QI regulating medicines such as Radix Bupleuri, Radix Aucklandiae (Radix Vladimiriae), vinegar Rhizoma Corydalis, be intended to disorders of blood gas control, make gas and blood peaceful, the stasis of blood is gone new life, and QI and blood is in harmonious proportion, and then the people is promptly peaceful.Because of diseases such as women's difficult menstruation, dysmenorrhoea, amenorrhea, difficult labour, retention of placenta, how by due to the blood stasis, and " stagnation of QI and blood may bring about pain " is the main predisposing factors that causes obstetrical and gynecological disease again; Drink again in the event side and add " the gas medicine in the blood " prepared RHIZOMA CHUAN XIONG with yellow rice wine blood-activating and qi-promoting, the raw peach kernel removing blood stasis to strengthen the merit of blood circulation and channel invigorating, disappears its " general rule is not bitterly ", the stasis of blood pain of loosing.Full side's blood stasis dispelling and do not hinder fresh blood is nourished blood and unlikely blood stasis, and is eliminating evil and do not forget to set upright.So row and poly-, mend and oiliness, reinforcement and elimination in combination, giving consideration to both the incidental and fundamental is to put pearls and jade together, and brings out the best in each other.This shows, the present invention's square medicine, dialectical legislation is original, and prescription is sent YAOJING and is worked as, and compatibility is ingenious rigorous, and the pathogenesis that hits again, is the rare good medicine of department of obstetrics and gynecology in fact.
The present invention is through clinical verification for many years, can extensively treat through multiple obstetrical and gynecological diseases such as, band, tire, products.About " diagnostic criteria of obstetrics and gynecology ", now 150 routine medical record final reports with complete are as follows for " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " of issuing according to State Administration of Traditional Chinese Medicine:
1, clinical data:
In 150 routine patients, age reckling 17 years old, the maximum 65 years old, the elder of the course of disease 20 years is the shortest 5 days.Dysmenorrhea 56 examples wherein, artificial abortion's postoperative bellyache 20 examples, puerperal abdonimal pain 16 Li , mass in the abdomen pain 8 examples, irregular menstrual period 13 example, amenorrhea 7 examples, metrorrhagia 6 examples, pelvic inflammatory disease 9 examples, lochiorrhea 8 examples, menstrual molimen disease 1 example, postpartum diarrhea 1 example, puerperal leucorrhea 3 examples, the edema of the face in puerperal 2 examples.
2, Therapeutic Method:
Among the collected 150 routine patients of this paper, its pathogenic factor is the multiple disease of department of obstetrics and gynecology that qi depression to blood stasis causes, and existing " syndrome of blood stasis " main witness in clinical is summarized as follows:
(1), pain: by the pain due to " syndrome of blood stasis ", its characteristics are that the position is fixed, sore spot tenderness, or piece is arranged by it, pain is obstinate, violent, shows as distending pain, twinge, dull pain etc.Common as dysmenorrhea, pelvic pain, mass in the abdomen pain, puerperal abdonimal pain and artificial abortion's postoperative bellyache etc.
(2), hemorrhage: " syndrome of blood stasis " hemorrhage, as metrorrhagia (anovulatory dysfunctional uterine hemorrhage), vaginal bleeding during pregnancy hematochezia or postpartum lochiorrhea, epistaxis and hematemesis during menstruation, tubal pregnancy (ectopic pregnancy), can make the sering damage inner hemorrhage, it is dim red or purple black that its color mostly is, or folder stasis of blood piece, and with diseases such as stomachache.
(3), mass in the abdomen: by De mass in the abdomen due to " syndrome of blood stasis ", as hysteromyoma, ovarian cyst, inflammatory masses of pelvic cavity, endometriosis.Its characteristics for lay one's hand on tangible, push away do not move the pain of pressure.
(4), menoxenia: by the change in menstrual cycle due to " syndrome of blood stasis ", its purple coloured menses is black or dim red, and is thick and hold stasis of blood piece under the arm through matter.
(5), neural mental symptom: " syndrome of blood stasis " can cause spirit depressing, crieses and laugh by turns, without any apparent reason, and some neurological symptoms such as intractable headache occur.As invasion of the blood-chamber by heat, premenstrual tension syndrome etc.
(6), other: disease meeting portion is dark dim dark with two cheekbones or forehead, and the eyes socket of the eye is black dull, as wears glasses, and xerosis cutis does not have the pool, very then squamous and dry skin.There are ecchymosis, petechia (general how the appearance) in purplish tongue or sharp limit in prolonged illness or the long-pending tangible disease of the stasis of blood.Pulse condition sinks string or heavy.
According to 6 main witnesses of above-mentioned obstetrical and gynecological disease, differentiate further that it is cold, heat, different clinical manifestations such as empty, real, can with card in addition different guiding drugs treat.
3, criterion of therapeutical effect and therapeutic outcome:
(1), criterion of therapeutical effect:
Cure: clinical symptoms and sign are all eliminated, and efficacy consolidation.
Produce effects: though clinical symptoms is eliminated, curative effect is consolidated inadequately.
Effectively: clinical symptoms and sign make moderate progress.
Invalid: no change before and after the treatment.
(2), therapeutic outcome:
In 150 routine clinical observations, 60 examples of fully recovering, produce effects 61 examples, effective 22 examples, invalid 7 examples, total effective rate reaches 96.39%.
The specific embodiment
Embodiment 1
The medicine of treatment obstetrical and gynecological disease, its composition and content are: 30 parts of Stigma Crocis, 30 parts of Radix Notoginsengs, 60 parts of Radix Angelicae Sinensis (processed with wine), 30 parts of Rhizoma Cyperi (processed with vinegar), 30 parts of vinegar Rhizoma Corydalis, 30 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of raw peach kernels, 30 parts of prepared RHIZOMA CHUAN XIONG with yellow rice wine, process 30 parts of Radix Bupleuri, every part is 1 to restrain;
Its production method is as follows:
(1). choose Radix Angelicae Sinensis (processed with wine), Rhizoma Cyperi (processed with vinegar), vinegar Rhizoma Corydalis, Radix Aucklandiae (Radix Vladimiriae), raw peach kernel, prepared RHIZOMA CHUAN XIONG with yellow rice wine, process the water logging bubble 24 hours that Radix Bupleuri seven flavor Chinese medicines add ten times of doses according to above-mentioned weight proportion;
(2). decoct three times:, leach behind the medicinal liquid stand-by for the first time with slow fire boiling 3 hours; The decocting that adds for the second time seven times of doses boiled 2 hours, leached behind the medicinal liquid stand-by; The decocting that adds five times of doses for the third time boiled 1 hour, leached behind the medicinal liquid stand-by;
(3). merge three times decocting liquid, filter;
(4). be concentrated into relative density and be the thick paste of 1.23-1.26 (60 °-65 °), stand-by.
(5). it is stand-by according to choosing Stigma Croci, Radix Notoginseng two flavor Chinese medicines in the weight proportion, to choose and wear into fine powder behind the clean impurity, sieve;
(6). Chinese medicines such as above-mentioned Radix Angelicae Sinensis (processed with wine) are concentrated Chinese medicine fine powder mix homogeneously such as thick paste and Stigma Croci;
(7). cold drying;
(8). wear into fine powder, sieve;
(9). divide encapsulated;
(10). concentrate with the sterilization of cobalt 60 x ray irradiation xs the sealing back.
Embodiment 2
The medicine of treatment obstetrical and gynecological disease, its composition and content are: 10 parts of Stigma Crocis, 10 parts of Radix Notoginsengs, 20 parts of Radix Angelicae Sinensis (processed with wine), 10 parts of Rhizoma Cyperi (processed with vinegar), 10 parts of vinegar Rhizoma Corydalis, 10 parts of Radix Aucklandiae (Radix Vladimiriae), 10 parts of raw peach kernels, 10 parts of prepared RHIZOMA CHUAN XIONG with yellow rice wine are processed 10 parts of Radix Bupleuri, every part 1 gram;
Its production method is as follows:
(1). choose Radix Angelicae Sinensis (processed with wine), Rhizoma Cyperi (processed with vinegar), vinegar Rhizoma Corydalis, Radix Aucklandiae (Radix Vladimiriae), raw peach kernel, prepared RHIZOMA CHUAN XIONG with yellow rice wine, process the water logging bubble 24 hours that Radix Bupleuri seven flavor Chinese medicines add ten times of doses according to weight proportion;
(2). decoct three times:, leach behind the medicinal liquid stand-by for the first time with slow fire boiling 3 hours; The decocting that adds for the second time seven times of doses boiled 2 hours, leached behind the medicinal liquid stand-by; The decocting that adds five times of doses for the third time boiled 1 hour, leached behind the medicinal liquid stand-by;
(3). merge three times decocting liquid, filter;
(4). be concentrated into relative density and be the thick paste of 1.23-1.26 (60 °-65 °), stand-by.
(5). it is stand-by according to choosing Stigma Croci, Radix Notoginseng two flavor Chinese medicines in the weight proportion, to choose and wear into fine powder behind the clean impurity, sieve;
(6). Chinese medicines such as above-mentioned Radix Angelicae Sinensis (processed with wine) are concentrated Chinese medicine fine powder mix homogeneously such as thick paste and Stigma Croci;
(7). cold drying;
(8). wear into fine powder, sieve;
(9). divide encapsulated;
(10). concentrate with the sterilization of cobalt 60 x ray irradiation xs the sealing back.
Claims (2)
1, a kind of medicine for the treatment of obstetrical and gynecological disease is characterized in that: made by following materials of weight proportions:
30 parts of 30 portions of Radix Notoginsengs of Stigma Croci
30 parts of 60 parts of Rhizoma Cyperi (processed with vinegar) of Radix Angelicae Sinensis (processed with wine)
30 parts of 30 portions of Radix Aucklandiae (Radix Vladimiriae) of vinegar Rhizoma Corydalis
30 parts of 30 parts of prepared RHIZOMA CHUAN XIONG with yellow rice wine of raw peach kernel
Process 30 parts of Radix Bupleuri.
2, prepare the method for the described treatment obstetrical and gynecological disease of claim 1 medicine, it is characterized in that:
(1). choose Radix Angelicae Sinensis (processed with wine), Rhizoma Cyperi (processed with vinegar), vinegar Rhizoma Corydalis, Radix Aucklandiae (Radix Vladimiriae), raw peach kernel, prepared RHIZOMA CHUAN XIONG with yellow rice wine, process water logging bubble 12-36 hour that Radix Bupleuri seven flavor Chinese medicines add 5-15 times of dose according to weight proportion;
(2). decoct three times:, leach behind the medicinal liquid stand-by for the first time with slow fire boiling 1.5-4.5 hour; The decocting that adds for the second time 3.5-10.5 times of dose boiled 1-3 hour, leached behind the medicinal liquid stand-by; The decocting that adds 2.5-7.5 times of dose for the third time boiled 0.5-1.5 hour, leached behind the medicinal liquid stand-by;
(3). merge three times decocting liquid, filter;
(4). be concentrated into the thick paste of relative density, stand-by;
(5). it is stand-by according to choosing Stigma Croci, Radix Notoginseng two flavor Chinese medicines in the weight proportion, to choose and wear into fine powder behind the clean impurity, sieve;
(6). above-mentioned Chinese medicine is concentrated thick paste and Chinese medicine fine powder mix homogeneously;
(7). cold drying;
(8). wear into fine powder, sieve;
(9). divide encapsulated,
(10). concentrate with the sterilization of cobalt 60 x ray irradiation xs the sealing back.
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CN 02135955 CN1215854C (en) | 2002-11-29 | 2002-11-29 | Medicine for treating gynaecology and obstetrics disease and preparation method |
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Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1314438C (en) * | 2004-04-15 | 2007-05-09 | 周盘吉 | Medication for curing stomac ache of women's menses |
CN102274411B (en) * | 2011-08-08 | 2013-04-03 | 刘帆 | Medicine bag and traditional Chinese medicine preparation for treating menoxenia and dysmenorrhea |
CN102526415B (en) * | 2012-01-06 | 2013-09-11 | 刘梅 | Chinese medicinal composition for treating dysmenorrhea and preparation method of same |
CN104258292A (en) * | 2014-10-10 | 2015-01-07 | 夏放军 | Drug for department of obstetrics and gynecology for treating pregnancy complication and manufacturing method thereof |
CN104225407A (en) * | 2014-10-10 | 2014-12-24 | 夏放军 | Obstetrics and gynecology drug for treating postnatal depression and production method thereof |
CN105233070A (en) * | 2015-11-18 | 2016-01-13 | 杜英凤 | Traditional Chinese medicine composition for treating dysmenorrhea |
CN105381141A (en) * | 2015-11-18 | 2016-03-09 | 杜英凤 | Preparation method of melilotus extract tablet for treating dysmenorrhea |
CN105341658A (en) * | 2015-11-18 | 2016-02-24 | 杜英凤 | Instant powder for treatment of dysmenorrhea and preparation method thereof |
CN105232866A (en) * | 2015-11-18 | 2016-01-13 | 杜英凤 | Traditional Chinese medicine pills for treating dysmenorrhea and preparation method thereof |
CN112516233A (en) * | 2019-09-17 | 2021-03-19 | 李鹏 | Saffron crocus oral liquid and preparation method thereof |
CN112826884B (en) * | 2021-03-22 | 2022-07-19 | 中南大学湘雅二医院 | Traditional Chinese medicine composition for treating metrorrhagia and metrostaxis and/or postpartum lochiorrhea, preparation method thereof and traditional Chinese medicine preparation |
CN114377099A (en) * | 2021-12-29 | 2022-04-22 | 湖南汉方神农中医馆有限公司 | Novel blood-activating menstruation-regulating granule medicine and preparation method thereof |
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