CN100346812C - Medicine for treating hyperplasia of mammary glands and fibroadenoma of breast and prepn. technique - Google Patents
Medicine for treating hyperplasia of mammary glands and fibroadenoma of breast and prepn. technique Download PDFInfo
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- CN100346812C CN100346812C CNB2006100201078A CN200610020107A CN100346812C CN 100346812 C CN100346812 C CN 100346812C CN B2006100201078 A CNB2006100201078 A CN B2006100201078A CN 200610020107 A CN200610020107 A CN 200610020107A CN 100346812 C CN100346812 C CN 100346812C
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Abstract
The present invention discloses a medicine for treating hyperplasia of mammary glands and breast benign fibroma. The medicine comprises the following active ingredients: 5 to 10 of figwort root, 5 to 10 of nutgrass galingale rhizome, 5 to 10 of deglued antler, 5 to 10 of common anemarrhena rhizome, 5 to 10 of red sage root, 5 to 10 of oyster shell, 10 to 15 of dandelion, 5 to 10 of green tangerine peel, 5 to 10 of white peony root, 10 to 15 of epimedium herb, 10 to 15 of thunberg fritillary bulb and 6 to 11 of white mustard seed. The medicine of the present invention can be prepared into any preparation suitable for clinic by using a convention preparation method of a Chinese medicine preparation, preferably a capsule. The experiment indicates that the medicine of the present invention has the advantages of conspicuous curative effect, no toxic or side effect, convenient administration and fabrication, etc. for treating hyperplasia of mammary glands and breast benign fibroma.
Description
Technical field
The present invention relates to the optimum fibromatous medicine of a kind of treatment mastopathy and breast, particularly relating to a kind of is treatment disease of hyperplasia of mammary glands glands and optimum fibromatous medicine of breast and the preparation technology that raw material is made with Chinese medicine.
Technical background
" gynecological beautiful chi " says: " woman's disease concerns the most huge person breast that woulds be better ".Lump in breast is current women's commonly encountered diseases, a frequently-occurring disease, be intramammary a kind of chronic non-inflammation disease, its clinical manifestation symptom mostly is: occur lump in the breast, quality is medium, smooth surface, unsteady, clear-cut margin, with skin and deep breast muscle adhesion, lump does not increases slowly, through preceding distending pain etc., modern medicine does not still have special effect medicine therapeutic, how based on operative treatment, but the general frightened operation of patient is ready to take Chinese medicine.
The existing medicine that is used for the treatment of cyclomastopathy class disease mainly contains RUKANG PIAN, RUKUAIXIAO PIAN, newborn disease spirit granule, the diffusing sheet of nodule in the breast etc. on the market, but all there are defectives such as curative effect is remarkable inadequately to some extent in these medicines.
Summary of the invention
Purpose of the present invention just is to overcome the deficiencies in the prior art, providing a kind of is treatment disease of hyperplasia of mammary glands glands and optimum fibromatous medicine of breast and the preparation technology that raw material is made with Chinese medicine, this curative effect of medication significantly, have no side effect, taking convenience, simple for production.
The objective of the invention is to be achieved through the following technical solutions: treatment disease of hyperplasia of mammary glands glands and the optimum fibromatous medicine of breast, its active component is made up of following component by weight ratio: Radix Scrophulariae 5-10, Rhizoma Cyperi 5-10, Cornu Cervi Degelatinatum 5-10, Rhizoma Anemarrhenae 5-10, Radix Salviae Miltiorrhizae 5-10, Concha Ostreae 5-10, Herba Taraxaci 10-15, Pericarpium Citri Reticulatae Viride 5-10, Radix Paeoniae Alba 5-10, Herba Epimedii 10-15, Bulbus Fritillariae Thunbergii 10-15, Semen Sinapis Albae 6-11.
Its active component is made up of following component by weight ratio: Radix Scrophulariae 7, Rhizoma Cyperi 7, Cornu Cervi Degelatinatum 7, the Rhizoma Anemarrhenae 7, Radix Salviae Miltiorrhizae 7, Concha Ostreae 7, Herba Taraxaci 12, Pericarpium Citri Reticulatae Viride 7, the Radix Paeoniae Alba 7, Herba Epimedii 12, Bulbus Fritillariae Thunbergii 12, Semen Sinapis Albae 8;
The optimum fibromatous medicine of treatment disease of hyperplasia of mammary glands glands of the present invention and breast can adopt the conventional formulation method of Chinese medicine preparation to be prepared into any suitable clinical preparation, for example can be tablet, capsule, granule, pill, oral liquid etc., preferably capsule.
The preparation technology of treatment disease of hyperplasia of mammary glands glands and the optimum fibromatous medicine of breast, its step is as follows:
(1) take by weighing each raw material by following weight ratio:
Radix Scrophulariae 5-10, Rhizoma Cyperi 5-10, Cornu Cervi Degelatinatum 5-10, Rhizoma Anemarrhenae 5-10, Radix Salviae Miltiorrhizae 5-10, Concha Ostreae 5-10, Herba Taraxaci 10-15, Pericarpium Citri Reticulatae Viride 5-10, Radix Paeoniae Alba 5-10, Herba Epimedii 10-15, Bulbus Fritillariae Thunbergii 10-15, Semen Sinapis Albae 6-11.
(2) Cornu Cervi Degelatinatum, Bulbus Fritillariae Thunbergii, Pericarpium Citri Reticulatae Viride are ground into 120 order fine powders, sieve, get coarse powder and fine powder, stand-by;
(3) with above-mentioned coarse powder and Radix Scrophulariae, Rhizoma Cyperi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Concha Ostreae, Herba Taraxaci, the Radix Paeoniae Alba, Herba Epimedii, Semen Sinapis Albae totally nine flavors decoct with water secondary, each 1-3 hour, collecting decoction, filtration, filtrate were concentrated into relative density 1: 30-1: 32 (60 ℃);
(4) above-mentioned fine powder mixing is prepared into tablet, capsule, granule, pill or oral liquid.
The preparation technology of treatment disease of hyperplasia of mammary glands glands of the present invention and the optimum fibromatous medicine of breast, its step is as follows:
(1) take by weighing each raw material by following weight ratio:
The medicine of Radix Scrophulariae 7, Rhizoma Cyperi 7, Cornu Cervi Degelatinatum 7, the Rhizoma Anemarrhenae 7, Radix Salviae Miltiorrhizae 7, Concha Ostreae 7, Herba Taraxaci 12, Pericarpium Citri Reticulatae Viride 7, the Radix Paeoniae Alba 7, Herba Epimedii 12, Bulbus Fritillariae Thunbergii 12, Semen Sinapis Albae 8;
(2) Cornu Cervi Degelatinatum, Bulbus Fritillariae Thunbergii, Pericarpium Citri Reticulatae Viride are ground into fine powder, sieve, get coarse powder and fine powder, stand-by;
(3) with above-mentioned coarse powder and Radix Scrophulariae, Rhizoma Cyperi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Concha Ostreae, Herba Taraxaci, the Radix Paeoniae Alba, Herba Epimedii, Semen Sinapis Albae totally nine flavors decoct with water secondary, each 2 hours, collecting decoction, filtration, filtrate were concentrated into relative density 1: 30-1: 32 (60 ℃);
(4) above-mentioned fine powder mixing is made tablet, capsule, granule, pill, oral liquid etc., preferably capsule.
The dosage of medicine of the present invention is relevant with dosage form, patient's age and health status etc.For referencial use with capsule: oral, one time 3～4,3 times on the one, taking, serve on March after meal half an hour is a course of treatment.
The invention provides treatment disease of hyperplasia of mammary glands glands and the optimum fibromatous medicine of breast, is that raw material is made with Chinese medicine, have evident in efficacy, have no side effect, taking convenience and advantage such as simple for production.
The specific embodiment
Embodiment 1: present embodiment is a most preferred embodiment of the present invention, treatment disease of hyperplasia of mammary glands glands and the optimum fibromatous medicine of breast, its active component is made up of following component by weight ratio: the medicine of Radix Scrophulariae 7, Rhizoma Cyperi 7, Cornu Cervi Degelatinatum 7, the Rhizoma Anemarrhenae 7, Radix Salviae Miltiorrhizae 7, Concha Ostreae 7, Herba Taraxaci 12, Pericarpium Citri Reticulatae Viride 7, the Radix Paeoniae Alba 7, Herba Epimedii 12, Bulbus Fritillariae Thunbergii 12, Semen Sinapis Albae 8;
The preparation of capsule:
(1) take by weighing each raw material by following weight ratio:
The medicine of Radix Scrophulariae 7, Rhizoma Cyperi 7, Cornu Cervi Degelatinatum 7, the Rhizoma Anemarrhenae 7, Radix Salviae Miltiorrhizae 7, Concha Ostreae 7, Herba Taraxaci 12, Pericarpium Citri Reticulatae Viride 7, the Radix Paeoniae Alba 7, Herba Epimedii 12, Bulbus Fritillariae Thunbergii 12, Semen Sinapis Albae 8;
(2) Cornu Cervi Degelatinatum, Bulbus Fritillariae Thunbergii, Pericarpium Citri Reticulatae Viride are ground into fine powder, sieve, get coarse powder and fine powder, stand-by;
(3) with above-mentioned coarse powder and Radix Scrophulariae, Rhizoma Cyperi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Concha Ostreae, Herba Taraxaci, the Radix Paeoniae Alba, Herba Epimedii, Semen Sinapis Albae totally nine flavors decoct with water secondary, each 2 hours, collecting decoction, filtration, filtrate were concentrated into relative density 1: 30 (60 ℃);
(4) above-mentioned fine powder mixing is made granule, and drying is put into capsule.
Embodiment 2: treatment disease of hyperplasia of mammary glands glands and the optimum fibromatous medicine of breast, its active component is made up of following component by weight ratio: Radix Scrophulariae 5, Rhizoma Cyperi 5, Cornu Cervi Degelatinatum 5, the Rhizoma Anemarrhenae 5, Radix Salviae Miltiorrhizae 5, Concha Ostreae 5, Herba Taraxaci 10, Pericarpium Citri Reticulatae Viride 5, the Radix Paeoniae Alba 5, Herba Epimedii 10, Bulbus Fritillariae Thunbergii 10, Semen Sinapis Albae 6.
The preparation of oral liquid:
(1) take by weighing each raw material by following weight ratio:
Radix Scrophulariae 5, Rhizoma Cyperi 5, Cornu Cervi Degelatinatum 5, the Rhizoma Anemarrhenae 5, Radix Salviae Miltiorrhizae 5, Concha Ostreae 5, Herba Taraxaci 10, Pericarpium Citri Reticulatae Viride 5, the Radix Paeoniae Alba 5, Herba Epimedii 10, Bulbus Fritillariae Thunbergii 10, Semen Sinapis Albae 6.
(2) Cornu Cervi Degelatinatum, Bulbus Fritillariae Thunbergii, Pericarpium Citri Reticulatae Viride are ground into 120 order fine powders, sieve, get coarse powder and fine powder, stand-by;
(3) with above-mentioned coarse powder and Radix Scrophulariae, Rhizoma Cyperi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Concha Ostreae, Herba Taraxaci, the Radix Paeoniae Alba, Herba Epimedii, Semen Sinapis Albae totally nine flavors decoct with water secondary, each 1 hour, collecting decoction, filtration, filtrate were concentrated into relative density 1: 31 (60 ℃);
(4) above-mentioned fine powder mixing is prepared into oral liquid.
Embodiment 3: treatment disease of hyperplasia of mammary glands glands and the optimum fibromatous medicine of breast, its active component is made up of following component by weight ratio: Radix Scrophulariae 10, Rhizoma Cyperi 10, Cornu Cervi Degelatinatum 10, the Rhizoma Anemarrhenae 10, Radix Salviae Miltiorrhizae 10, Concha Ostreae 10, Herba Taraxaci 15, Pericarpium Citri Reticulatae Viride 10, the Radix Paeoniae Alba 10, Herba Epimedii 15, Bulbus Fritillariae Thunbergii 15, Semen Sinapis Albae 11.
The preparation of tablet:
(1) takes by weighing each raw material by following weight ratio: Radix Scrophulariae 10, Rhizoma Cyperi 10, Cornu Cervi Degelatinatum 10, the Rhizoma Anemarrhenae 10, Radix Salviae Miltiorrhizae 10, Concha Ostreae 10, Herba Taraxaci 15, Pericarpium Citri Reticulatae Viride 10, the Radix Paeoniae Alba 10, Herba Epimedii 15, Bulbus Fritillariae Thunbergii 15, Semen Sinapis Albae 11.
(2) Cornu Cervi Degelatinatum, Bulbus Fritillariae Thunbergii, Pericarpium Citri Reticulatae Viride are ground into 120 order fine powders, sieve, get coarse powder and fine powder, stand-by;
(3) with above-mentioned coarse powder and Radix Scrophulariae, Rhizoma Cyperi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Concha Ostreae, Herba Taraxaci, the Radix Paeoniae Alba, Herba Epimedii, Semen Sinapis Albae totally nine flavors decoct with water secondary, each 1 hour, collecting decoction, filtration, filtrate were concentrated into relative density 1: 32 (60 ℃);
(4) above-mentioned fine powder mixing is prepared into tablet.
The clinical observation test of medicine of the present invention:
(1) physical data
Accept female patient for medical treatment and amount to 286 examples, the age is between 18～45 years old.
(2) severity extent
Breast carcinoma then pathology is shorter, lump quality as hard as flint, and the surface is uneven, blur margin Chu, the skin nuclear phase connects, and what push away does not move, diabrosis in late period, shape such as cauliflower, sharp ache.This is a carcinoid fundamental difference in breast carcinoma and the breast.It is ill all around that the contact of the two shows that then the disease gene all centers on breast.
(3) Therapeutic Method
Oral 3 times of every day, per 3～4, take half an hour after meal, 3 months is a course of treatment.
(4) efficacy assessment standard
Cure: the lump in breast complete obiteration; Take a turn for the better: the lump area dwindles, and quality deliquescing activity is obvious; Invalid: lump obviously increases redness.
(5) therapeutic outcome
Cyclomastopathy, cystic hyperplasia of breast, the adenosis of breast lump is a lamellar, tuberosity such as beading sample, promptly cure half course of treatment.The above person of the optimum fibrous tumours 2～3cm of breast takes the nodule in the breast capsule and cures 2 courses of treatment.
Observe in 286 examples, cure 274 examples, 12 examples take a turn for the better.Cure rate is 92%, and total effective rate reaches 100%.
Claims (6)
1. treat disease of hyperplasia of mammary glands glands and the optimum fibromatous medicine of breast for one kind, it is characterized in that: its active component is made by following Chinese medicine raw materials by weight proportion:
Radix Scrophulariae 5-10, Rhizoma Cyperi 5-10, Cornu Cervi Degelatinatum 5-10, Rhizoma Anemarrhenae 5-10, Radix Salviae Miltiorrhizae 5-10, Concha Ostreae 5-10, Herba Taraxaci 10-15, Pericarpium Citri Reticulatae Viride 5-10, Radix Paeoniae Alba 5-10, Herba Epimedii 10-15, Bulbus Fritillariae Thunbergii 10-15, Semen Sinapis Albae 6-11.
2. a kind of treatment disease of hyperplasia of mammary glands glands according to claim 1 and the optimum fibromatous medicine of breast, it is characterized in that: its active component is made by following Chinese medicine raw materials by weight proportion: the medicine of Radix Scrophulariae 7, Rhizoma Cyperi 7, Cornu Cervi Degelatinatum 7, the Rhizoma Anemarrhenae 7, Radix Salviae Miltiorrhizae 7, Concha Ostreae 7, Herba Taraxaci 12, Pericarpium Citri Reticulatae Viride 7, the Radix Paeoniae Alba 7, Herba Epimedii 12, Bulbus Fritillariae Thunbergii 12, Semen Sinapis Albae 8.
3. a kind of treatment disease of hyperplasia of mammary glands glands according to claim 1 and the optimum fibromatous medicine of breast, it is characterized in that: described medicine is tablet, capsule, granule, pill or oral liquid.
4. a kind of treatment disease of hyperplasia of mammary glands glands according to claim 3 and the optimum fibromatous medicine of breast, it is characterized in that: described medicine is a capsule.
5. as claim 1 or 3 described a kind of preparation technologies that treat disease of hyperplasia of mammary glands glands and the optimum fibromatous medicine of breast, it is characterized in that its step is as follows:
(1) take by weighing each raw material by following weight ratio:
Radix Scrophulariae 5-10, Rhizoma Cyperi 5-10, Cornu Cervi Degelatinatum 5-10, Rhizoma Anemarrhenae 5-10, Radix Salviae Miltiorrhizae 5-10, Concha Ostreae 5-10, Herba Taraxaci 10-15, Pericarpium Citri Reticulatae Viride 5-10, Radix Paeoniae Alba 5-10, Herba Epimedii 10-15, Bulbus Fritillariae Thunbergii 10-15, Semen Sinapis Albae 6-11;
(2) Cornu Cervi Degelatinatum, Bulbus Fritillariae Thunbergii, Pericarpium Citri Reticulatae Viride are ground into 120 order fine powders, sieve, get coarse powder and fine powder, stand-by;
(3) with above-mentioned coarse powder and Radix Scrophulariae, Rhizoma Cyperi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Concha Ostreae, Herba Taraxaci, the Radix Paeoniae Alba, Herba Epimedii, Semen Sinapis Albae totally nine flavors decoct with water secondary, each 1-3 hour, relative density 1.30-1.32 when collecting decoction, filtration, filtrate are concentrated into 60 ℃;
(4) above-mentioned fine powder mixing is prepared into tablet, capsule, granule, pill or oral liquid.
6. a kind of preparation technology who treats disease of hyperplasia of mammary glands glands and the optimum fibromatous medicine of breast according to claim 5 is characterized in that its step is as follows:
(1) takes by weighing each raw material by following weight ratio: Radix Scrophulariae 7, Rhizoma Cyperi 7, Cornu Cervi Degelatinatum 7, the Rhizoma Anemarrhenae 7, Radix Salviae Miltiorrhizae 7, Concha Ostreae 7, Herba Taraxaci 12, Pericarpium Citri Reticulatae Viride 7, the Radix Paeoniae Alba 7, Herba Epimedii 12, Bulbus Fritillariae Thunbergii 12, Semen Sinapis Albae 8;
(2) Cornu Cervi Degelatinatum, Bulbus Fritillariae Thunbergii, Pericarpium Citri Reticulatae Viride are ground into 120 order fine powders, sieve, get coarse powder and fine powder, stand-by;
(3) with above-mentioned coarse powder and Radix Scrophulariae, Rhizoma Cyperi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Concha Ostreae, Herba Taraxaci, the Radix Paeoniae Alba, Herba Epimedii, Semen Sinapis Albae totally nine flavors decoct with water secondary, each 2 hours, relative density 1.30-1.32 when collecting decoction, filtration, filtrate are concentrated into 60 ℃;
(4) above-mentioned fine powder mixing, drying is made capsule.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100201078A CN100346812C (en) | 2006-01-05 | 2006-01-05 | Medicine for treating hyperplasia of mammary glands and fibroadenoma of breast and prepn. technique |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2006100201078A CN100346812C (en) | 2006-01-05 | 2006-01-05 | Medicine for treating hyperplasia of mammary glands and fibroadenoma of breast and prepn. technique |
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| Publication Number | Publication Date |
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| CN1833712A CN1833712A (en) | 2006-09-20 |
| CN100346812C true CN100346812C (en) | 2007-11-07 |
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| CNB2006100201078A Expired - Fee Related CN100346812C (en) | 2006-01-05 | 2006-01-05 | Medicine for treating hyperplasia of mammary glands and fibroadenoma of breast and prepn. technique |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732528B (en) * | 2010-02-10 | 2011-06-22 | 李蕴 | Chinese medicament for treating of hyperplasia of mammary gland |
| CN101919963B (en) * | 2010-08-02 | 2011-11-30 | 靳照礼 | Traditional Chinese medicine composition as well as preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1182618A (en) * | 1997-12-15 | 1998-05-27 | 黄国锁 | Medicine for curing mamary gland disease and preparation method thereof |
| CN1404867A (en) * | 2002-11-12 | 2003-03-26 | 吉林华康药业股份有限公司 | Chinese medicine for treating hyperplasia of mammary glands |
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2006
- 2006-01-05 CN CNB2006100201078A patent/CN100346812C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1182618A (en) * | 1997-12-15 | 1998-05-27 | 黄国锁 | Medicine for curing mamary gland disease and preparation method thereof |
| CN1404867A (en) * | 2002-11-12 | 2003-03-26 | 吉林华康药业股份有限公司 | Chinese medicine for treating hyperplasia of mammary glands |
Non-Patent Citations (1)
| Title |
|---|
| 乳腺增生病中医治疗进展 徐英纳.中医药临床杂志，第16卷第6期 2004 * |
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