CN102526415B - Chinese medicinal composition for treating dysmenorrhea and preparation method of same - Google Patents
Chinese medicinal composition for treating dysmenorrhea and preparation method of same Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition for treating dysmenorrhea and a preparation method of the Chinese medicinal composition and belongs to the field of Chinese medicines. The Chinese medicinal composition is prepared by the following raw materials in percentage by weight: 3 to 18 of Radix Salviae Miltiorrhizae, 3 to 18 of vinegar-processed Corydalis yanhusuo, 15 to 25 of Crocus sativus flower, 3 to 15 of wine-processed Paeonia lactiflora, 5 to 12 of wine-processed Angelica sinensis, 5 to 12 of Radix Notoginseng, 6 to 12 of Leonurus japonicus, 2 to 8 of Rhizoma Cyperi, 3 to12 of Melia toosendan, 2 to 6 of Radix Bupleuri, 2 to 6 of common fennel and 6 to 12 of honeyed licorice root. The Chinese medicinal composition has the effects of promoting blood flow and removing blood stasis, invigorating qi and nourishing blood and relieving depression of the liver-qi, can be used for treating dysmenorrha, and has the advantages of definite efficacy, rapid onset of action, complete healing and less side effect.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of dysmenorrhea and preparation method thereof.
Background technology
Dysmenorrhea is called " abdominal pain during menstruation ", frequently-occurring disease common for gynecological in Chinese medicine.Clinical symptoms is through row lower abdomen pain, follows menstrual cycle and shows effect, and severe patient can occur that abdominal part has an intense pain, pale complexion, cold extremities, even faints, and brings very large misery to the women, has a strong impact on their work and quality of life.Dysmenorrhea is divided into two kinds of constitutional and Secondary cases clinically, and primary dysmenorrhea is followed before and after the menstruation outside the stomachache, and genitals does not have the significant organic pathological changes, claims primary dysmenorrhea again; Secondary dysmenorrhea refers to because the dysmenorrhea that pelvic cavity organic disease such as endometriosis, adenomyosis, pelvic inflammatory disease or cervical stenosis cause.
TREATMENT OF DYSMENORRHOEA has Chinese medicine and Western medicine at present, the Western medicine good analgesic effect, and instant effect, but action time is short, can not fundamentally solve the dysmenorrhea problem, Western medicine side effect simultaneously is big, often takes, and that can give patient healthyly brings certain threat.Compare with Western medicine, treatment by Chinese herbs thoroughly, effect is lasting, untoward reaction is few, and therefore more people are partial to adopt treatment by Chinese herbs dysmenorrhea problem.But the problem that present treatment by Chinese herbs dysmenorrhea exists is to take effect slowly.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of dysmenorrhea and preparation method thereof, this traditional Chinese medicine composition for treating dysmenorrhea determined curative effect, instant effect, thorough treatment, side effect is little.
The present invention is achieved through the following technical solutions, and a kind of Chinese medicine composition for the treatment of dysmenorrhea is characterized in that, it is prepared from by the following weight parts proportion raw material:
Chinese medicine composition of the present invention is formed by the feedstock production of following weight parts:
Radix Salviae Miltiorrhizae 3-18, vinegar Rhizoma Corydalis 3-18, Stigma Croci 15-25, Radix Paeoniae Alba 3-15, Radix Angelicae Sinensis (processed with wine) 5-12, Radix Notoginseng 5-12, Herba Leonuri 6-12, Rhizoma Cyperi 2-8, Fructus Toosendan 3-12, Radix Bupleuri 2-6, Fructus Foeniculi 2-6 and Radix Glycyrrhizae (processed with honey) 6-12.
Chinese medicine composition of the present invention is preferably formed by the feedstock production of following weight parts:
Radix Salviae Miltiorrhizae 15, vinegar Rhizoma Corydalis 15 Stigma Crocis 20, Radix Paeoniae Alba 12, Radix Angelicae Sinensis (processed with wine) 10, Radix Notoginseng 10, Herba Leonuri 10, Rhizoma Cyperi 6, Fructus Toosendan 9, Radix Bupleuri 5, Fructus Foeniculi 3 and Radix Glycyrrhizae (processed with honey) 10.
The present invention also provides the preparation method of preferred this Chinese medicine composition, and this method comprises the steps:
(1), choosing the water that all crude drug except Stigma Croci add 5-10 times of dose according to weight proportion soaked respectively 6-12 hour;
(2), get soak back Rhizoma Cyperi and Fructus Foeniculi and merge after, vapor distillation extracts volatile oil, volatile oil is stand-by; Medicinal liquid filters stand-by;
(3), decoct: get soak back Radix Salviae Miltiorrhizae, vinegar Rhizoma Corydalis, Radix Paeoniae Alba, Radix Angelicae Sinensis (processed with wine), Radix Notoginseng, Herba Leonuri, Fructus Toosendan, Radix Bupleuri and Radix Glycyrrhizae (processed with honey) and merge after, slow fire boiling 4 hours leaches behind the medicinal liquid stand-by; The decocting that adds for the second time 3-6 times of dose boiled 2 hours, leached behind the medicinal liquid stand-by; The decocting that adds 2-4 times of dose for the third time boiled 1 hour, leached behind the medicinal liquid stand-by;
(4), all filtrate in abovementioned steps (2) and (3) is merged, the thick paste of relative density 1.15-1.30 is stand-by when being concentrated into temperature 70-75 ℃;
(5), choose Stigma Croci according to weight proportion, wear into fine powder behind the decontamination, sieve stand-by;
(6), the volatile oil mix homogeneously that obtains of the Stigma Croci fine powder that obtains of the concentrated solution thick paste that above-mentioned steps (4) is obtained, step (5) and step (2);
(7), make the dosage form that needs according to routine techniques.
The successive dynasties traditional Chinese medical science was done many trial to the treatment dysmenorrhea, accumulated rich practice experience and theoretical basis, the traditional Chinese medical science is thought and caused that the dysmenorrhea main cause roughly can be summarized as following 4 points: one is qi depression to blood stasis, and two is QI and blood deficiency, three is cold and stagnate, and four is deficiency of both the liver and kidney; Write in " Song Shi woman the secretary of section ": " through the water person that do not have a pain in the future, stagnation of QI and blood also, a burst of person of having a pain in the abdomen controls when taking good care of QI and blood.Theory of Chinese medical science is thought the pathogenesis of dysmenorrhea, for QI and blood obstructed, stagnation of QI and blood may bring about pain.And the physiological function of QI and blood and liver is closely related, and the traditional Chinese medical science is thought, liver storing blood, department's sea of blood, and liver controlling conveyance and dispersion, catharsis is harmonizing the functional activities of vital QI, promotes sanguimotor important step, the catharsis function is normal, then QI movement being in harmonious way, QI and blood and accent.The present invention is as theoretical foundation, adopts the Chinese herbal medicine formula of blood circulation promoting and blood stasis dispelling, benefiting qi and nourishing blood, depressed liver-energy dispersing and QI regulating, can quickly alleviating pain, and thorough treatment dysmenorrhea had significant curative effect.
Drug action mechanism of the present invention is as follows:
Radix Salviae Miltiorrhizae bitter in the mouth, cold nature, GUIXIN, Liver Channel; Has the blood stasis removing pain relieving, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire; Describe Radix Salviae Miltiorrhizae in " book on Chinese herbal medicine converges and says ": control blood system, remove the tissue regeneration promoting that stagnates, regulating menstruation along the feeling pulse medicine also.The wine Rhizoma Corydalis is warm in nature, and the acrid in the mouth hardship is gone into the heart, spleen, liver, lung meridian, is the quality goods of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, especially with the effect of pain relieving claim in generation; Li Shizhen (1518-1593 A.D.) is concluded Rhizoma Corydalis in Compendium of Material Medica have " invigorating blood circulation promoting the circulation of QI, pain relieving, diuresis " four large effects, and praise highly Rhizoma Corydalis " stagnation of QI in the energy promoting the circulation of blood, stasis in the gas is so specially control the whole body all pains up and down ".Stigma Croci sweet in the mouth, little suffering, property is flat, GUIXIN, Liver Channel; Has blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens, the effect of removing pathogenic heat from blood and toxic substance from the body.This three flavors medicine mainly plays the effect of blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia.
Radix Paeoniae Alba bitter in the mouth, acid, cold nature is returned liver, spleen channel, has the suppressing the hyperactive liver pain relieving, the effect of nourishing blood for regulating menstruation, relieving spasm to stop pain, yin fluid astringing suppressing the hyperactive liver.The Radix Notoginseng sweet and slightly bitter taste, warm in nature, return liver, stomach warp, have hemostasis, dissipating blood stasis, detumescence, the effect of pain relieving, put down in writing in Qing Dynasty's pharmacy works supplementary Amplifications of the Compendium of Materia Medica: " ginseng qi-tonifying first; Radix Notoginseng enriches blood the first, flavor with and merit also waits, so claim Panax pseudoginseng, be the most precious person in the Chinese medicine." the modern Chinese medicine pharmacological research confirms that also Radix Notoginseng has significant hemopoietic function.Radix Angelicae Sinensis (processed with wine) sweet in the mouth, suffering, warm in nature, return liver, the heart, spleen channel, having enriches blood invigorates blood circulation, the effect of menstruction regulating and pain relieving.Herba Leonuri acrid in the mouth hardship, be slightly cold, return liver, pericardium channel, have the effect of regulating menstruation and activating blood, promoting tissue regeneration by removing blood stasis.This four Chinese medicine mainly plays the effect of the tissue regeneration promoting that nourishes blood.
The Rhizoma Cyperi acrid in the mouth, property is flat, returns liver, tri-jiao channel, has soothing the liver, the menstruction regulating and pain relieving effect of regulating the flow of vital energy.Fructus Toosendan bitter in the mouth, cold in nature is returned liver, small intestinal, urinary bladder channel, and function is soothing liver-QI, promoting the circulation of QI to relieve pain.Radix Bupleuri hardship, suffering are slightly cold.Return liver, gallbladder meridian, the kind bar of property reaches irritability, dispersing the stagnated live-QI to relieve the stagnation of QI, hepatic depression and blood deficiency elevate a turnable ladder yang-energy.Fructus Foeniculi is warm in nature, and acrid in the mouth is returned liver,kidney,spleen, stomach warp, and function is warming the liver kidney, warming the stomach gas, plug knot, dispersing cold for relieving pain, regulating qi-flowing for harmonizing stomach loose.Four have the effect of depressed liver-energy dispersing and QI regulating.Radix Glycyrrhizae (processed with honey) sweet in the mouth, property are put down, and have and middle emergency, invigorating the spleen and replenishing QI the effect of coordinating the actions of various ingredients in a prescription.
Above-mentioned Chinese medicine is through organic assembling, dialectical compatibility and assist a ruler in governing a country mutually, has strengthened the effect of this medicine blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, benefiting qi and nourishing blood, thereby reaches the purpose of rapid healing dysmenorrhea.
The present invention can effectively treat dysmenorrhea through clinical verification for many years." the disease of tcm diagnosis criterion of therapeutical effect " of promulgating according to State Administration of Traditional Chinese Medicine is about " diagnostic criteria of obstetrics and gynecology ", and 50 routine medical record final reports are as follows:
1, clinical data:
In 50 routine patients, age reckling 14 years old, the maximum 45 years old, the elder of the course of disease 20 years is the shortest 10 days.Primary dysmenorrhea 20 examples wherein, secondary dysmenorrhea 30 examples.
2, Therapeutic Method
Medicine is formed and weight: Radix Salviae Miltiorrhizae 15, vinegar Rhizoma Corydalis 15, Stigma Croci 20, Radix Paeoniae Alba 12, Radix Angelicae Sinensis (processed with wine) 10, Radix Notoginseng 10, Herba Leonuri 10, Rhizoma Cyperi 6, Fructus Toosendan 9, Radix Bupleuri 5, Fructus Foeniculi 3 and Radix Glycyrrhizae (processed with honey) 10.Make granule according to above method.Once a day, each 10, every 0.25 gram, each warp before serve on 7 days and gets final product.
3, criterion of therapeutical effect and therapeutic outcome
(1) criterion of therapeutical effect
Cure: clinical symptoms and sign are all eliminated, and efficacy consolidation.
Produce effects: though clinical symptoms is eliminated, curative effect is consolidated inadequately.
Effectively: clinical symptoms and sign make moderate progress.
Invalid: no change before and after the treatment.
(2) therapeutic outcome
In 50 routine clinical observations, 17 examples of fully recovering, produce effects 19 examples, effective 12 examples, invalid 2 examples, total effective rate 96%.During the treatment, all patients do not see the obvious adverse reaction report, show that we's treatment dysmenorrhea is safe and effective.
The specific embodiment
Embodiment 1
Chinese medicine composition of the present invention is formed by the feedstock production of following weight parts:
Radix Salviae Miltiorrhizae 15, vinegar Rhizoma Corydalis 18, Stigma Croci 20, Radix Paeoniae Alba 3, Radix Angelicae Sinensis (processed with wine) 12, Radix Notoginseng 10, Herba Leonuri 10, Rhizoma Cyperi 6, Fructus Toosendan 9, Radix Bupleuri 5, Fructus Foeniculi 3 and Radix Glycyrrhizae (processed with honey) 10.
The preparation method of this Chinese medicine composition comprises the steps:
(1), choosing the water that all crude drug except Stigma Croci add 6 times of doses according to weight proportion soaked respectively 10 hours;
(2), get soak back Rhizoma Cyperi and Fructus Foeniculi and merge after, vapor distillation extracts volatile oil, volatile oil is stand-by; Medicinal liquid filters stand-by;
(3), decoct: get soak back Radix Salviae Miltiorrhizae, vinegar Rhizoma Corydalis, Radix Paeoniae Alba, Radix Angelicae Sinensis (processed with wine), Radix Notoginseng, Herba Leonuri, Fructus Toosendan, Radix Bupleuri and Radix Glycyrrhizae (processed with honey) and merge after, slow fire boiling 4 hours leaches behind the medicinal liquid stand-by; The decocting that adds for the second time 4 times of doses boiled 2 hours, leached behind the medicinal liquid stand-by; The decocting that adds 2 times of doses for the third time boiled 1 hour, leached behind the medicinal liquid stand-by;
(4), all filtrate in abovementioned steps (2) and (3) is merged, the thick paste of relative density 1.15 is stand-by when being concentrated into 75 ℃ of temperature;
(5), choose Stigma Croci according to weight proportion, wear into 100 order fine powders behind the decontamination, sieve stand-by;
(6), the volatile oil mix homogeneously that obtains of the Stigma Croci fine powder that obtains of the concentrated solution thick paste that above-mentioned steps (4) is obtained, step (5) and step (2);
(7), make granule according to routine techniques.
Wherein: Radix Paeoniae Alba, Radix Angelicae Sinensis (processed with wine), vinegar Rhizoma Corydalis and Radix Glycyrrhizae (processed with honey) are existing concocting method, specifically:
Radix Paeoniae Alba: get 100 kilograms of Radix Paeoniae Alba sheets, mix thoroughly for 10 kilograms with wine, vexed slightly, treat that wine is exhausted, fry to little yellow with slow fire, take out spreading for cooling.
Radix Angelicae Sinensis (processed with wine) is the processed with wine processed goods of the dry root of umbelliferae angelica.
Radix Glycyrrhizae (processed with honey): refined honey is added an amount of boiled water dilution, admix medicine and treat that sweet liquid suction is saturating, put in the heat pot and constantly fry to buff, with loose tack-free degree of being, the taking-up airing.
Vinegar Rhizoma Corydalis: get clean Rhizoma Corydalis, mix thoroughly with vinegar, soak into, to the vinegar exhaustion, put in the pot and fry to little dried with slow fire, take out, cool; Or get clean Rhizoma Corydalis, and put in the pot with vinegar and boil altogether, to the vinegar exhaustion, oven dry is taken out, and cools.(100 jin of every Rhizoma Corydalis are with 20 jin of vinegar).
Embodiment 2
Chinese medicine composition of the present invention is formed by the feedstock production of following weight parts:
Radix Salviae Miltiorrhizae 18, vinegar Rhizoma Corydalis 3, Stigma Croci 15, Radix Paeoniae Alba 15, Radix Angelicae Sinensis (processed with wine) 5, Radix Notoginseng 12, Herba Leonuri 12, Rhizoma Cyperi 8, Fructus Toosendan 12, Radix Bupleuri 6, Fructus Foeniculi 6 and Radix Glycyrrhizae (processed with honey) 12.
The preparation method of this Chinese medicine composition comprises the steps:
(1), choosing the water that all crude drug except Stigma Croci add 10 times of doses according to weight proportion soaked respectively 12 hours;
(2), get soak back Rhizoma Cyperi and Fructus Foeniculi and merge after, vapor distillation extracts volatile oil, volatile oil is stand-by; Medicinal liquid filters stand-by;
(3), decoct: get soak back Radix Salviae Miltiorrhizae, vinegar Rhizoma Corydalis, Radix Paeoniae Alba, Radix Angelicae Sinensis (processed with wine), Radix Notoginseng, Herba Leonuri, Fructus Toosendan, Radix Bupleuri and Radix Glycyrrhizae (processed with honey) and merge after, slow fire boiling 4 hours leaches behind the medicinal liquid stand-by; The decocting that adds for the second time 5 times of doses boiled 2 hours, leached behind the medicinal liquid stand-by; The decocting that adds 4 times of doses for the third time boiled 1 hour, leached behind the medicinal liquid stand-by;
(4), all filtrate in abovementioned steps (2) and (3) is merged, the thick paste of relative density 1.30 is stand-by when being concentrated into 70 ℃ of temperature;
(5), choose Stigma Croci according to weight proportion, wear into fine powder behind the decontamination, sieve stand-by;
(6), the volatile oil mix homogeneously that obtains of the Stigma Croci fine powder that obtains of the concentrated solution thick paste that above-mentioned steps (4) is obtained, step (5) and step (2);
(7), make the tablet that needs according to routine techniques.
Wherein: Radix Paeoniae Alba, Radix Angelicae Sinensis (processed with wine), vinegar Rhizoma Corydalis and Radix Glycyrrhizae (processed with honey) are existing concocting method.
Embodiment 3
Chinese medicine composition of the present invention is formed by the feedstock production of following weight parts:
Radix Salviae Miltiorrhizae 3, vinegar Rhizoma Corydalis 3, Stigma Croci 15, Radix Paeoniae Alba 3, Radix Angelicae Sinensis (processed with wine) 5, Radix Notoginseng 5, Herba Leonuri 6, Rhizoma Cyperi 2, Fructus Toosendan 3, Radix Bupleuri 2, Fructus Foeniculi 2 and Radix Glycyrrhizae (processed with honey) 6.
Method by embodiment 1 is made capsule.
Embodiment 4
Chinese medicine composition of the present invention is formed by the feedstock production of following weight parts:
Radix Salviae Miltiorrhizae 3, vinegar Rhizoma Corydalis 18, Stigma Croci 20, Radix Paeoniae Alba 8, Radix Angelicae Sinensis (processed with wine) 12, Radix Notoginseng 8, Herba Leonuri 12, Rhizoma Cyperi 2, Fructus Toosendan 5, Radix Bupleuri 4, Fructus Foeniculi 3 and Radix Glycyrrhizae (processed with honey) 6.
Method by embodiment 2 is made tablet.
Embodiment 5
Chinese medicine composition of the present invention is formed by the feedstock production of following weight parts:
Radix Salviae Miltiorrhizae 15, vinegar Rhizoma Corydalis 15, Stigma Croci 20, Radix Paeoniae Alba 12, Radix Angelicae Sinensis (processed with wine) 10, Radix Notoginseng 10, Herba Leonuri 10, Rhizoma Cyperi 6, Fructus Toosendan 9, Radix Bupleuri 5, Fructus Foeniculi 3 and Radix Glycyrrhizae (processed with honey) 10.
Method by embodiment 2 is made tablet.
Claims (3)
1. a Chinese medicine composition for the treatment of dysmenorrhea is characterized in that, is formed by the feedstock production of following weight parts:
Radix Salviae Miltiorrhizae 3-18, vinegar Rhizoma Corydalis 3-18, Stigma Croci 15-25, Radix Paeoniae Alba 3-15, Radix Angelicae Sinensis (processed with wine) 5-12, Radix Notoginseng 5-12, Herba Leonuri 6-12, Rhizoma Cyperi 2-8, Fructus Toosendan 3-12, Radix Bupleuri 2-6, Fructus Foeniculi 2-6 and Radix Glycyrrhizae (processed with honey) 6-12;
(1), choosing the water that all crude drug except Stigma Croci add 5-10 times of dose according to above-mentioned weight proportion soaked respectively 6-12 hour;
(2), get soak back Rhizoma Cyperi and Fructus Foeniculi and merge after, vapor distillation extracts volatile oil, volatile oil is stand-by; Medicinal liquid filters stand-by;
(3), decoct: get soak back Radix Salviae Miltiorrhizae, vinegar Rhizoma Corydalis, Radix Paeoniae Alba, Radix Angelicae Sinensis (processed with wine), Radix Notoginseng, Herba Leonuri, Fructus Toosendan, Radix Bupleuri and Radix Glycyrrhizae (processed with honey) and merge after, slow fire boiling 4 hours leaches behind the medicinal liquid stand-by; The decocting that adds for the second time 3-6 times of dose boiled 2 hours, leached behind the medicinal liquid stand-by; The decocting that adds 2-4 times of dose for the third time boiled 1 hour, leached behind the medicinal liquid stand-by;
(4), all filtrate in abovementioned steps (2) and (3) is merged, the thick paste of relative density 1.15-1.30 is stand-by when being concentrated into temperature 70-75 ℃;
(5), choose Stigma Croci according to weight proportion, wear into fine powder behind the decontamination, sieve stand-by;
(6), the volatile oil mix homogeneously that obtains of the Stigma Croci fine powder that obtains of the concentrated solution thick paste that above-mentioned steps (4) is obtained, step (5) and step (2);
(7), make the dosage form that needs according to routine techniques.
2. the Chinese medicine composition for the treatment of dysmenorrhea according to claim 1 is characterized in that, is formed by the feedstock production of following weight parts:
Radix Salviae Miltiorrhizae 15, vinegar Rhizoma Corydalis 15, Stigma Croci 20, Radix Paeoniae Alba 12, Radix Angelicae Sinensis (processed with wine) 10, Radix Notoginseng 10,
Herba Leonuri 10, Rhizoma Cyperi 6, Fructus Toosendan 9, Radix Bupleuri 5, Fructus Foeniculi 3 and Radix Glycyrrhizae (processed with honey) 10.
3. a method for preparing claim 1 or 2 described Chinese medicine compositions comprises the steps:
(1), choosing the water that all crude drug except Stigma Croci add 5-10 times of dose according to weight proportion soaked respectively 6-12 hour;
(2), get soak back Rhizoma Cyperi and Fructus Foeniculi and merge after, vapor distillation extracts volatile oil, volatile oil is stand-by; Medicinal liquid filters stand-by;
(3), decoct: get soak back Radix Salviae Miltiorrhizae, vinegar Rhizoma Corydalis, Radix Paeoniae Alba, Radix Angelicae Sinensis (processed with wine), Radix Notoginseng, Herba Leonuri, Fructus Toosendan, Radix Bupleuri and Radix Glycyrrhizae (processed with honey) and merge after, slow fire boiling 4 hours leaches behind the medicinal liquid stand-by; The decocting that adds for the second time 3-6 times of dose boiled 2 hours, leached behind the medicinal liquid stand-by; The decocting that adds 2-4 times of dose for the third time boiled 1 hour, leached behind the medicinal liquid stand-by;
(4), all filtrate in abovementioned steps (2) and (3) is merged, the thick paste of relative density 1.15-1.30 is stand-by when being concentrated into temperature 70-75 ℃;
(5), choose Stigma Croci according to weight proportion, wear into fine powder behind the decontamination, sieve stand-by;
(6), the volatile oil mix homogeneously that obtains of the Stigma Croci fine powder that obtains of the concentrated solution thick paste that above-mentioned steps (4) is obtained, step (5) and step (2);
(7), make the dosage form that needs according to routine techniques.
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| CN104840757A (en) * | 2015-06-04 | 2015-08-19 | 李永生 | Traditional Chinese medicine preparation for alleviating dysmenorrheal and preparation method |
| CN112516233A (en) * | 2019-09-17 | 2021-03-19 | 李鹏 | Saffron crocus oral liquid and preparation method thereof |
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