CN1208626A - Bone strengthening pill and its preparation method - Google Patents
Bone strengthening pill and its preparation method Download PDFInfo
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- CN1208626A CN1208626A CN97115214A CN97115214A CN1208626A CN 1208626 A CN1208626 A CN 1208626A CN 97115214 A CN97115214 A CN 97115214A CN 97115214 A CN97115214 A CN 97115214A CN 1208626 A CN1208626 A CN 1208626A
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- gram
- necrosis
- bone strengthening
- radix
- femoral head
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- 238000002360 preparation method Methods 0.000 title claims abstract description 4
- 210000000988 bone and bone Anatomy 0.000 title abstract description 6
- 239000006187 pill Substances 0.000 title abstract description 5
- 238000005728 strengthening Methods 0.000 title abstract 4
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract description 3
- 229910052802 copper Inorganic materials 0.000 claims abstract description 3
- 239000010949 copper Substances 0.000 claims abstract description 3
- 239000003814 drug Substances 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 4
- 238000004659 sterilization and disinfection Methods 0.000 claims description 4
- 241000756943 Codonopsis Species 0.000 claims description 2
- 241001550206 Colla Species 0.000 claims description 2
- 241000209020 Cornus Species 0.000 claims description 2
- 241001489978 Eupolyphaga Species 0.000 claims description 2
- 241000628997 Flos Species 0.000 claims description 2
- 241000217407 Margaritifera Species 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 239000006260 foam Substances 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 238000012856 packing Methods 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 230000005855 radiation Effects 0.000 claims description 2
- 238000003756 stirring Methods 0.000 claims description 2
- 206010028851 Necrosis Diseases 0.000 abstract description 13
- 230000017074 necrotic cell death Effects 0.000 abstract description 13
- 230000000302 ischemic effect Effects 0.000 abstract description 7
- 208000007875 Femur Head Necrosis Diseases 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 6
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 235000009917 Crataegus X brevipes Nutrition 0.000 abstract 1
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 abstract 1
- 235000009685 Crataegus X maligna Nutrition 0.000 abstract 1
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 abstract 1
- 235000009486 Crataegus bullatus Nutrition 0.000 abstract 1
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 abstract 1
- 235000009682 Crataegus limnophila Nutrition 0.000 abstract 1
- 235000004423 Crataegus monogyna Nutrition 0.000 abstract 1
- 240000000171 Crataegus monogyna Species 0.000 abstract 1
- 235000002313 Crataegus paludosa Nutrition 0.000 abstract 1
- 235000009840 Crataegus x incaedua Nutrition 0.000 abstract 1
- 241000218671 Ephedra Species 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 241000237502 Ostreidae Species 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 abstract 1
- 239000003292 glue Substances 0.000 abstract 1
- 235000020636 oyster Nutrition 0.000 abstract 1
- 230000002146 bilateral effect Effects 0.000 description 12
- 208000002193 Pain Diseases 0.000 description 9
- 230000037182 bone density Effects 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 210000001624 hip Anatomy 0.000 description 5
- 210000004197 pelvis Anatomy 0.000 description 5
- 210000000689 upper leg Anatomy 0.000 description 5
- 208000006820 Arthralgia Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 210000004394 hip joint Anatomy 0.000 description 4
- 230000001788 irregular Effects 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 206010005963 Bone formation increased Diseases 0.000 description 2
- 206010028289 Muscle atrophy Diseases 0.000 description 2
- 210000002745 epiphysis Anatomy 0.000 description 2
- 210000002414 leg Anatomy 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 230000020763 muscle atrophy Effects 0.000 description 2
- 201000000585 muscular atrophy Diseases 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 108010048734 sclerotin Proteins 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 206010002027 Amyotrophy Diseases 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 206010006895 Cachexia Diseases 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 206010016654 Fibrosis Diseases 0.000 description 1
- 206010024453 Ligament sprain Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 201000000023 Osteosclerosis Diseases 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- 238000003723 Smelting Methods 0.000 description 1
- 208000010040 Sprains and Strains Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001217 buttock Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 208000026500 emaciation Diseases 0.000 description 1
- 201000010934 exostosis Diseases 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 210000002391 femur head Anatomy 0.000 description 1
- 210000002436 femur neck Anatomy 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000004761 fibrosis Effects 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000011164 ossification Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000000452 restraining effect Effects 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001694 thigh bone Anatomy 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to a bone strengthening pill for treating femoral ischemic necrosis and a preparation method thereof, and the formula comprises 15 to 50 g of radix codonopsitis, 10 to 50 g of rhizoma drynariae, 9 to 30 g of magnet, 100 g of prepared rhizome of rehmannia, 40 to 50 g of ephedra, 10 to 50 g of deerhorn glue, 20 to 50 g of angelica, 20 to 50 g of salvia miltiorrhiza, 9 to 50 g of raw yam, 10 to 50 g of safflower, 15 to 50 g of raw oyster, 15 to 50 g of raw keel, 20 to 50 g of hawthorn and 6 to 10 g of native copper. The bone strengthening pill can cure ischemic necrosis of femoral head without operation and sequela after being taken, the cure rate is as high as 90.74 percent, the effective rate is 100 percent, and the bone strengthening pill has special effect on ischemic femoral necrosis of different parts of people of all ages and both sexes.
Description
The present invention relates to a kind of ZHUANGGU WAN and system affair method thereof for the treatment of ischemic necrosis of femoral head.
The western medical treatment ischemic necrosis of femoral head generally is to adopt surgical operation, promptly necrosis is partly excised, and the people is disabled.
The objective of the invention is to develop a kind of without surgical operation, the ZHUANGGU WAN of specially for treating caput femoris ischemic necrosis and method for making thereof.
The prescription of ZHUANGGU WAN of the present invention is as follows:
Radix Codonopsis 15-50 gram, Rhizoma Drynariae 10-50 gram, Magnetitum 9-30 gram, Radix Rehmanniae Preparata 100 grams, Herba Ephedrae 40-50 gram, Colla cornus cervi 10-50 gram, Radix Angelicae Sinensis 20-50 gram, Radix Salviae Miltiorrhizae 20-50 gram, Rhizoma Dioscoreae 9-50 gram, Flos Carthami 10-50 gram, give birth to male 15-50 gram, Os Draconis 15-50 gram, Fructus Crataegi 20-50 gram, Pyritum 6-10 gram.
Optimum formula is to add following component on the basis of above-mentioned prescription again: Rhizoma Dioscoreae 8-10 gram, eupolyphaga 7-10 gram, Concha Margaritifera 10-15 gram.
Above-mentioned dosage banburying becomes ball, can do 120 balls, about 9 grams of every ball.
The preparation method of ZHUANGGU WAN is as follows:
1. pick up the interior silt particle of clean medicine, foreign material etc., remove powder such as earth and foreign material with the scalping sieve;
2. by the coarse pulverization of said ratio elder generation, regrind into fine powder, stir;
3. use the ultraviolet radiation disinfection fine powder;
4. with the Mel heating and filtering, reuse copper pot decocts, and removes clean wax foam, endures to dropping liquid Cheng Zhu;
5. above-mentioned medicated powder and Mel are stirred, the garden of making about nine grams of every ball is spherical, after paper that the use disinfection by ultraviolet light is crossed and the wax shell packing, seals with wax.
The situation of clinical treatment is as follows:
Patient's situation:
Male's 86 examples in this group case, women's 22 examples.Age: 16 examples below 10 years old, 11-20 year 18 examples, 21-31 year 10 examples, 31-41 year 23 examples, 41-51 year 26 examples, 15 examples more than 51 years old.The course of disease: 1 year with interior person's 31 examples, 1-3 39 examples, 4-6 person's 25 examples, person's 13 examples more than 6 years.Site of pathological change: left side femur head necrosis person 40 examples, right lateral thigh head necrosis person 45 examples, bad the dead of bilateral femoral head 23 examples.
Instructions of taking: six o'clock of morning begins to take medicine, and every 6 hours clothes one balls, children's was cut down according to the circumstance.Period in a medicine is prohibited all hormone medicines of clothes, forbids drinking the restraining sexual life.After generally taking medicine 10-30 days, pain obviously alleviates, and after one month, sclerotin is repaired gradually, and disease is almost recovered after 4 to 6 months.
The treatment standard:
Effectively: through taking this medicine after 6 months, pain disappears or alleviates, suffer from the movable obviously improvement of limb, the X line is taken the photograph shown in the sheet, and epiphysis is irregular minute nodular, and the pathological changes epiphysis is subjected to gravity effect because of area of new bone, can flatten and increase in density, especially the femoral neck osteoporosis is more remarkable near end of thighbone, and shortens, and broadens.Sometimes the cryptomere transparent area, the necrotic area that as seen differ in size have new bone formation can show as compact outer shell central authorities on every side and see downright bad osteocomma, can have a granulation tissue to absorb euphotic zone due to the sequestrum therebetween.
Therapeutic outcome: effective 108 people, account for 100%, recovery from illness: 98 people account for 90.74%.
Model case:
Case one:
Huge certain, man, 31 years old, Shanxi chemical fertilizer factory, cadre.After this waist lower limb discontinuity pain promptly occurred by bike accidentally with left sprain of hip in 90 years, it is invalid that local doctor treats by the rheumatism smelting.In May, 94 state of an illness aggravation, through the film making of X line, be diagnosed as the bilateral femoral head necrosis in Changzhi City peace hospital August.JIUYUE spends about 140,000 yuan of medical expense, unsatisfactory curative effect to Beijing promoting the circulation of blood pipe transplantation.Symptom is: the bilateral hip arthralgia, and limitation of activity, two leg muscle atrophys can not be walked with descending, emaciation and sallow complexion, pale tongue, tongue is white, stringy and thready pulse.Shown in the film making of X line, the pelvis ap sheet: the irregular summary of bilateral femoral head becomes flat, and bone density is inhomogeneous, has the cryptomere bone density to lower district and streak attenuating district therebetween, and the hip joint gap is slightly not wide, is outstanding with the right side.Impression: bilateral femoral head necrosis.Give the ZHUANGGU WAN treatment, every 6 hours one balls, after one month, pain obviously alleviated.After two months, can cane walking.Sclerotin was obviously repaired with after X line film making in three months, and the patient requires to go home medication treatment.Five months with the court's check afterwards, the pain complete obiteration, walking freely, joint movement function is good, can working work, X line film making finding (pelvis ap sheet) bilateral femoral head bone density has obviously than anter and increases, before there is reparation in capsule attenuating district, streak change is than the obvious increase in density of anter, and femoral head is out of shape, and the edge is more smooth.Impression: the bilateral femoral head necrosis is almost recovered.
Case two:
Xiong, man, 43 years old, Guyang County, Baotou, the Inner Mongol workman of rural power office.Nineteen ninety occurs lumbago and skelalgia because of work high above the ground after getting injured by a fall, and is bad during fashion, is diagnosed as the bilateral femoral head necrosis in the film making of the X of First People's Hospital, Inner Mongol line, and in December, 94 comes my institute's hospitalization.Disease is seen: double hip joint pain is radiated to two buttocks pain.Abduction, in accept orders for repairs or processing moving limitedly, the bilateral amyotrophy can not be squatted down, corpulent tongue is big and have tooth good, pale tongue, thready and weak pulse.X line film making finding, bone divides positive bit slice: bilateral femoral head becomes partially, hip joint gap broad.The femoral head density unevenness is even, and its inner structure disorder is outstanding with the left side, and the femoral head edge is slightly irregular.Impression: bilateral femoral head ischemic necrosis.Every 6 hours clothes ZHUANGGU WAN 1 balls, a month pain relief later on, later life in three months can be taken care of oneself and be left hospital.In June, 95 check, the patient is strong as ordinary person, X line film making finding, pelvis ap sheet: check, this film and anter compare, and bifilar bone density is more preceding obviously to be increased, and cystic lesion partly is that bar rope fiber and sclerosis change, the edge has hyperosteogeny to form, and closes standard width of a room in an old-style house crack and before narrows down, and the femoral head edge is more preceding smooth.Impression: the downright bad recovery from illness of bilateral femoral head.
Case three:
Fan, man, 47 years old, mesa township, Fangshan County, native place wang jiazhuang village village.Work unit: one work area, Luliang Prefecture power administration Fenyang, workman.The patient does not have obvious inducement and the right hip arthralgia occurs in January, 93, fails to respond to any medical treatment by " hyperosteogeny " in the Academy of Traditional Chinese Medicine, and through the film making of X line, be diagnosed as " right side ischemic necrosis of femoral head " in area just outside a city gate, Wenshui hospital February in this year.Symptom is: the right hip arthralgia, be radiated to also pain of groin, and tenderness is obvious, is bore spine sample pain.Right foot can not land, and walks lamely ..., the test of 4 words is positive, right leg muscle atrophy.The pale tongue tongue is white, deep-thready pulse.The film making of X line, the pelvis ap sheet: right femoral head becomes flat, and the slightly broadening of hip joint gap sees in its femoral head that irregular cryptomere density lowers district and osteosclerosis district, and local bone density is inhomogeneous, and the femoral head edge is slightly imperfect.Impression: right ischemic necrosis of femoral head.Through the clothes ZHUANGGU WAN, every 6 hours clothes one balls, all diseases disappeared with the court's check afterwards in five months, the work of having gone to work, shown in the film making of X line, the pelvis ap sheet: check, face femur density obviously increases than anter, cystic lesion trend fibrosis, the joint space before narrows down, neck of femur broadening and shortening, and there is osteophytosis its inboard.Impression: fl head ischemic necrosis recovery from illness.
In sum, the apparent effect of the present invention is as follows:
(1) the oral pill of the present invention of only need not performing the operation can be cured femur ischemic necrosis, cure rate Up to 90.74%, efficient 100%.
(2) this medicine has no side effect, and does not stay sequelae after healing, and is difficult for recurrence.
(3) all have for the men and women patient of all ages and classes and the ischemic femur necrosis at different onset position Special effect.
Claims (3)
1. ZHUANGGU WAN is characterized in that adopting following prescription:
Radix Codonopsis 15-50 gram, Rhizoma Drynariae 10-50 gram, Magnetitum 9-30 gram, Radix Rehmanniae Preparata 100 grams, Herba Ephedrae 40-50 gram, Colla cornus cervi 10-50 gram, Radix Angelicae Sinensis 20-50 gram, Radix Salviae Miltiorrhizae 20-50 gram, Rhizoma Dioscoreae 9-50 gram, Flos Carthami 10-50 gram, give birth to male 15-50 gram, Os Draconis 15-50 gram, Fructus Crataegi 20-50 gram, Pyritum 6-10 gram.
2. ZHUANGGU WAN as claimed in claim 1 is characterized in that having increased following component: Rhizoma Dioscoreae 8-10 gram, eupolyphaga 7-10 gram, Concha Margaritifera 10-15 gram.
3. the preparation method of ZHUANGGU WAN as claimed in claim 1 or 2 is characterized in that:
(1) picks up the interior silt particle of clean medicine, foreign material etc., remove powder such as earth and foreign material with the scalping sieve;
(2) by the coarse pulverization of said ratio elder generation, regrind into fine powder, stir;
(3) use the ultraviolet radiation disinfection fine powder;
(4) with the Mel heating and filtering, reuse copper pot decocts, and removes clean wax foam, endures to dropping liquid Cheng Zhu;
(5) above-mentioned medicated powder and Mel are stirred, the garden of making about nine grams of every ball is spherical, after paper that the use disinfection by ultraviolet light is crossed and the wax shell packing, seals with wax.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97115214A CN1056999C (en) | 1997-08-19 | 1997-08-19 | A Chinese medicinal pill for treating femoral head necrosis and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97115214A CN1056999C (en) | 1997-08-19 | 1997-08-19 | A Chinese medicinal pill for treating femoral head necrosis and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1208626A true CN1208626A (en) | 1999-02-24 |
| CN1056999C CN1056999C (en) | 2000-10-04 |
Family
ID=5173211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97115214A Expired - Fee Related CN1056999C (en) | 1997-08-19 | 1997-08-19 | A Chinese medicinal pill for treating femoral head necrosis and its preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1056999C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100335088C (en) * | 2005-06-29 | 2007-09-05 | 贵州同济堂制药股份有限公司 | Chinese medicine formulation for treating osteonecrosis and its preparing method |
| CN101199721B (en) * | 2007-12-14 | 2010-06-09 | 贾心红 | Chinese medicine pill for treating hip necrosis |
| CN1958027B (en) * | 2005-10-08 | 2011-01-26 | 刘国飞 | Composition of Chinese traditional medicine for treating necrosis of femoral head, and preparation method |
| CN105343475A (en) * | 2015-12-12 | 2016-02-24 | 杨献美 | Method for preparing traditional Chinese medicine preparation for treating female postmenopausal osteoporosis |
| CN110801466A (en) * | 2019-09-26 | 2020-02-18 | 志海医药科技(南京)有限公司 | Traditional Chinese medicine composition, preparation method and traditional Chinese medicine preparation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1095600A (en) * | 1992-11-26 | 1994-11-30 | 王璐林 | Bone regeneration pill |
| CN1105245A (en) * | 1993-06-10 | 1995-07-19 | 王进东 | Ronggukang capsule for curing bone disease |
-
1997
- 1997-08-19 CN CN97115214A patent/CN1056999C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100335088C (en) * | 2005-06-29 | 2007-09-05 | 贵州同济堂制药股份有限公司 | Chinese medicine formulation for treating osteonecrosis and its preparing method |
| CN1958027B (en) * | 2005-10-08 | 2011-01-26 | 刘国飞 | Composition of Chinese traditional medicine for treating necrosis of femoral head, and preparation method |
| CN101199721B (en) * | 2007-12-14 | 2010-06-09 | 贾心红 | Chinese medicine pill for treating hip necrosis |
| CN105343475A (en) * | 2015-12-12 | 2016-02-24 | 杨献美 | Method for preparing traditional Chinese medicine preparation for treating female postmenopausal osteoporosis |
| CN110801466A (en) * | 2019-09-26 | 2020-02-18 | 志海医药科技(南京)有限公司 | Traditional Chinese medicine composition, preparation method and traditional Chinese medicine preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1056999C (en) | 2000-10-04 |
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