CN101199721B - Chinese medicine pill for treating hip necrosis - Google Patents

Chinese medicine pill for treating hip necrosis Download PDF

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CN101199721B
CN101199721B CN2007101155137A CN200710115513A CN101199721B CN 101199721 B CN101199721 B CN 101199721B CN 2007101155137 A CN2007101155137 A CN 2007101155137A CN 200710115513 A CN200710115513 A CN 200710115513A CN 101199721 B CN101199721 B CN 101199721B
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radix
head necrosis
rhizoma
fructus
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CN101199721A (en
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贾心红
董海燕
高庆松
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Abstract

The invention discloses a Chinese traditional medicine pill for treating femoral head necrosis. The invention is characterized in that the medicine is prepared by the raw materials with the following weight proportion: Radix Rehmanniae Preparata 9-13 percent, Rhizoma Diosscoreae 5-10 percent, Fructus Corni 5-10 percent, Fructus Lycii 5-10 percent, Radix Notoginseng 3-6 percent, Eupolyphaga seu Steleophaga 3-6 percent, Radix Angelicae Sinensis 5-9 percent, Radix Salviae Miltiorrhizae 3-6 percent, Flos Carthami 3-6 percent, Semen Cuscutae 5-9 percent, Rhizoma Alismatis 3-6 percent, Radix Achyranthis Bidentatae 5-9 percent, Cortex Eucommiae (dried) 5-9 percent, Rhizoma Cibotii 3-6 percent, Radix Paeoniae Alba 3-6 percent and Fructus Chaenomelis 5-9 percent. The Chinese traditional medicine pill for treating femoral head necrosis contains drugs for nourishing liver and kidney, drugs for strengthening bone and promoting marrow regeneration and drugs for treating femoral head necrosis; thereby the invention can treat the femoral head necrosis without hurting heart, brain, liver, kidney, spleen, stomach and lung, without need of assistant therapy such as injection, crutch and traction; besides, with small dose, big drug potency, good absorption, convenient taking, safety, reliability and low treatment cost, the invention saves more treatment cost for patients.

Description

The Chinese medicine pill of treatment femur head necrosis
Technical field
The present invention relates to a kind of Chinese patent medicine, particularly a kind of Chinese medicine pill for the treatment of femur head necrosis.
Background technology
Femur head necrosis belongs to the traditional Chinese medical science " osteomyelitis " category, it is the difficult disease in the orthopaedics, but serious harm people's health, its cause of disease mainly is that the vigor composition of bone comprises osteocyte, myeloid element and adipose cell death, or ischemic necrosis of femoral head, thereby cause that the further ischemia of osteocyte, necrosis, bone trabecula rupture, a kind of pathological changes of collapse of the femoral head; Its exopathogenic factor comprises wound, hormone, excessive drinking or osteoporosis.At present, medical circle thinks that femur head necrosis has become frequently-occurring disease, commonly encountered diseases, and its pathological manifestations is an ischemic femoral head, and relatively consistent theory of generally acknowledging is that blood supply is obstructed.The clinical cardinal symptom of femur head necrosis shows as pain, can be intermittence or persistence, the Ambulatory Activity postemphasis, and pain mostly is acupuncture sample, dull pain or the discomfort etc. of aching, its ankylosis, limitation of activity; Next is the difficulty of squatting down, and can not stand for a long time; Because hip pain and collapse of the femoral head, or late period occurs hip joint subluxation and also can cause limping; Often occur intermittent claudication in early days, abduction, outward turning or inward turning limitation of activity are suffered from limb and can be shortened, amyotrophy, even the subluxation sign is arranged.The traditional Chinese medical science is thought: blockage of meridian, qi and blood stagnation, deficiency of the liver and kindey, the expectorant stasis of blood is blocked, and kidney is main bone etc. not, and the kidney being the origin of congenital constitution, main bone is given birth to marrow, and the strong then marrow of kidney fills, and bone is the bone heavily fortified point completely then, otherwise the marrow dry bones withers, and loses due regeneration capacity, and liver governing tendons is hidden it, the moving then blood of people is transported in all warps, and the quiet then blood of people belongs to liver, if the inconsiderate nutrition of blood transport contraband is not good, thereby cause femur head necrosis, therefore, the traditional Chinese medical science lays particular emphasis on non-operative treatment.Adopt the Chinese medicine of Chinese traditional treatment femur head necrosis also more, mainly start with from mediation blood network, blood circulation promoting regulates qi, strong muscles and bones, the cold expelling of enriching blood, tonifying liver stomach reinforcing, tissue regeneration promoting pain relieving, although certain curative effect is arranged, curative effect is still undesirable, and recurrence easily.Doctor trained in Western medicine adopts methods such as boring decompression, blood vessel grafting, free bone grafting operation, osteotomy, artificial joint replacement more, and its weak point is that operation risk is big, and the medical expense height can bring great misery to the patient, and effect is often undesirable.
Summary of the invention
The object of the present invention is to provide that a kind of good effect, expense are low, the Chinese medicine pill of the treatment femur head necrosis that has no side effect.
To achieve these objectives, the technical solution adopted in the present invention is: the Chinese medicine pill of this treatment femur head necrosis is characterized in that it is to be combined by weight percentage by following material medicine: Radix Rehmanniae Preparata 9-13%, Rhizoma Dioscoreae 5-10%, Fructus Corni 5-10%, Fructus Lycii 5-10%, Radix Notoginseng 3-6%, eupolyphaga 3-6%, Radix Angelicae Sinensis 5-9%, Radix Salviae Miltiorrhizae 3-6%, Flos Carthami 3-6%, Semen Cuscutae 5-9%, Rhizoma Alismatis 3-6%, cattle sunset 5-9%, the Cortex Eucommiae (stir-fry) 5-9%, Rhizoma Cibotii 3-6%, Radix Paeoniae Alba 3-6%, Fructus Chaenomelis 5-9%.
The optimum weight percentage ratio of material medicine of the present invention is: Radix Rehmanniae Preparata 11%, Rhizoma Dioscoreae 7%, Fructus Corni 8%, Fructus Lycii 7%, Radix Notoginseng 5%, eupolyphaga 4%, Radix Angelicae Sinensis 7%, Radix Salviae Miltiorrhizae 5%, Flos Carthami 4%, Semen Cuscutae 7%, Rhizoma Alismatis 4%, cattle sunset 7%, the Cortex Eucommiae (stir-fry) 7%, Rhizoma Cibotii 5%, the Radix Paeoniae Alba 5%, Fructus Chaenomelis 7%.
The preparation process of the Chinese medicine pill of this treatment femur head necrosis is:
1, material medicine is screened, remove impurity, dust;
2, the Cortex Eucommiae is operated parch routinely;
3, take by weighing by above percentage by weight: Radix Rehmanniae Preparata 9-13%, Rhizoma Dioscoreae 5-10%, Fructus Corni 5-10%, Fructus Lycii 5-10%, Radix Notoginseng 3-6%, eupolyphaga 3-6%, Radix Angelicae Sinensis 5-9%, Radix Salviae Miltiorrhizae 3-6%, Flos Carthami 3-6%, Semen Cuscutae 5-9%, Rhizoma Alismatis 3-6%, cattle sunset 5-9%, the Cortex Eucommiae (stir-fry) 5-9%, Rhizoma Cibotii 3-6%, Radix Paeoniae Alba 3-6%, Fructus Chaenomelis 5-9%;
4, mix pulverizing, cross 100 mesh sieves;
5, stir, refined honey is made pill, every ball 9 grams.
Instructions of taking: warm water delivery service, early, middle and late each one of every day, two months is a course of treatment.
Beneficial effect of the present invention is: because in the Chinese medicine of this treatment femur head necrosis, existing liver and kidney tonifying medicine, there is strong bone to mend the marrow medicine again, the strength of enriching blood in addition medicine and activating blood and removing stasis medicine, not sad, brain, liver,kidney,spleen, stomach, lung, need not have an injection, lean on turn, auxiliary therapy such as traction, and taking dose is little, the efficacy of a drug big, good absorbing, taking convenience, safe and reliable, medical expense is lower, for the patient has saved a large amount of medical expenses.
Curative effect judging standard:
Judge and rattan justice and criterion of therapeutical effect with reference to X-P in the 108th page " femur head necrosis therapeutic evaluation " in " integrative therapy femur head necrosis " (Guo Yongchang, Deng like the democracy volume, and publishing house of Henan Medical Univ. publishes) book.
(1) cure: pain disappears, and joint motion is normal, and X-P judges the existing picture that reparation is arranged.
(2) effective: pain obviously alleviates or disappearance substantially, and hip joint is movable obviously to be improved, and takes care of oneself, and abandons and turns walking, and X-P judges that the part sclerotin has the existing picture of reparation; Or pain relief, funtion part is recovered, and life still can be taken care of oneself, and X-P judgement stock index is repaired existing picture to some extent.
(3) invalid or DeGrain: pain does not subtract, walks lamely obviously, and the difficulty of squatting down, life inconvenience, X-P judges that bone destruction is serious.
The clinical practice data:
Adopt Chinese medicine pill treatment case 110 examples of this treatment femur head necrosis, all from this hospital orthopedics, 64 examples more than 50 years old wherein, 40-50 year 31 examples, 15 examples below 40 years old; The male has 75 examples, and the women has 35 examples; Wherein cure 81 examples, cure rate is 73.6%, effective 21 examples, and effective percentage is 19.1%, always effectively is 102 examples, total effective rate is 92.7%, invalid or DeGrain 8 examples, inefficiency is 7.3%.
Pharmacology of the present invention is:
Radix Rehmanniae Preparata: nourishing YIN and supplementing blood, should essence fill out marrow, be used for the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever;
Rhizoma Dioscoreae: sweet in the mouth is warm in nature, QI invigorating is arranged, is good for the stomach, suitable kidney, the function of mending strengthening spleen and lung;
Fructus Corni: nature and flavor acid, puckery, tepor, liver and kidney tonifying, arresting seminal emission hidroschesis, disease such as the soreness of waist that is used for deficiency of the liver and kindey is passed out semen, had a dizzy spell, menorrhagia and frequent micturition, spontaneous perspiration;
Fructus Lycii: nature and flavor are sweet, and are flat, nourishing the liver and kidney, and replenishing vital essence to improve eyesight is used for the asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear;
Radix Notoginseng: nature and flavor are little sweet and bitter, cure mainly hemostasis, diffusing blood, analgesic therapy;
Eupolyphaga: cold in nature, salty in the mouth, poisonous, the broken function of becoming silted up and stimulating the menstrual flow is arranged, cure mainly amenorrhea due to stagnation of blood, stomachache silt piece, diseases such as traumatic injury;
Radix Angelicae Sinensis: the sweet in the mouth suffering is warm in nature, and the effect of invigorating blood circulation of enriching blood is used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia;
Radix Salviae Miltiorrhizae: cold nature, little hardship has stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the function of the relieving restlessness that clears away heart-fire cures mainly menoxenia, amenorrhea dysmenorrhea, breast ventral spine pain, hepatosplenomegaly;
Flos Carthami: acrid in the mouth is warm in nature, and thin channels and activating collaterals is arranged, stimulating the menstrual flow silt, and reducing swelling and alleviating pain, removing pathogenic heat from blood and toxic substance from the body, the function of troubled thoughts pent-up cures mainly cerebral thrombosis, myocardial infarction, anemia body void, general aching, traumatic injury, neurasthenia etc.;
Semen Cuscutae: warm in nature, sweet in the mouth, nourishing the liver and kidney, the controlling nocturnal emission with astringent drugs reducing urination, antiabortive, make eye bright antidiarrheal;
Rhizoma Alismatis: feeble QI, mildly bitter flavor, diuresis, clearing away damp-heat;
Radix Acanthopanacis Bidentatae: give birth to and use dissipating blood stasis blood, detumescence is logical, controls gonorrhea, hematuria, amenorrhea;
The Cortex Eucommiae: the little suffering of sweet in the mouth, warm in nature, the invigorating the liver and kidney strengthening bone and muscle is arranged;
Rhizoma Cibotii: bitter, sweet, warm.Return liver, kidney channel, wind-damp dispelling, invigorating the liver and kidney, strong waist knee joint;
The Radix Paeoniae Alba: sour in the mouth hardship, cold nature, convergence replenishing YIN and blood effect is arranged, can the suppressing the hyperactive liver pain relieving;
Fructus Chaenomelis: acid, temperature.Return liver, spleen channel, help digestion, anthelmintic, heat clearing away is dispeled the wind.Cure mainly stomachache, dyspepsia, lung-heat dry cough, galactostasis, eczema, parasitic disease, diseases such as trick spasm pain.
The specific embodiment
Embodiment 1
Take by weighing crude drug of the present invention totally 100 gram, wherein Radix Rehmanniae Preparata 11g, Rhizoma Dioscoreae 7g, Fructus Corni 8g, Fructus Lycii 7g, Radix Notoginseng 5g, eupolyphaga 4g, Radix Angelicae Sinensis 7g, Radix Salviae Miltiorrhizae 5g, Flos Carthami 4g, Semen Cuscutae 7g, Rhizoma Alismatis 4g, cattle sunset 7g, the Cortex Eucommiae (stir-fry) 7g, Rhizoma Cibotii 5g, Radix Paeoniae Alba 5g, Fructus Chaenomelis 7g by optimum weight percentage ratio.
Make by following preparation process:
1, material medicine is screened, remove impurity, dust;
2, the Cortex Eucommiae is operated parch routinely;
3, mix pulverizing, cross 100 mesh sieves;
4, stir, refined honey is made pill, every ball 9 grams.
Instructions of taking: warm water delivery service, two months was-course of treatment at early, middle and late each one of every day.
The Chinese medicine pill made from this prescription carries out clinical treatment observation to 61 patients of femur head necrosis, wherein cures 50 examples, effective 10 examples, invalid or DeGrain 1 example.
Case 1: Wang Zhong, the man, 45 years old, caused left side femoral head cracked, subside because of wound June calendar year 2001, and the distortion of interior 1/4 place is suffered from limb and serious hindrance occurred, leans on crutches.In November, 2006, come the court to take Drug therapy of the present invention, after the course of treatment, the basic healing thrown away crutches, cure fully after taking 2 courses of treatment again, activity freely, X-P judges the phenomenon that reparation is arranged.
Case 2: Shi Yucheng, man, 55 years old, be fl head sterile type ischemic necrosis through this hospital diagnosis in January, 2007, and through inquiring, the patient is once through how tame hospitalize, not only invalid, be on the rise on the contrary, the femoral head crown subsides, and sequestrum is arranged, bone density increases, but the transmittance inequality, walking disorder is walked lamely, and stool is inconvenient.Take 3 courses of treatment of medicine of the present invention, sill is cured, the new osteogenesis of X radiodiagnosis x, and sequestrum is absorbed gradually, and bone density is even, and articular surface is smooth and continuous comparatively.X-P judges the phenomenon of repairing to some extent.
Embodiment 2
Take by weighing crude drug of the present invention totally 100 gram, wherein Radix Rehmanniae Preparata 13g, Rhizoma Dioscoreae 10g, Fructus Corni 10g, Fructus Lycii 10g, Radix Notoginseng 3g, eupolyphaga 3g, Radix Angelicae Sinensis 5g, Radix Salviae Miltiorrhizae 3g, Flos Carthami 3g, Semen Cuscutae 9g, Rhizoma Alismatis 6g, cattle sunset 9g, the Cortex Eucommiae (stir-fry) 5g, Rhizoma Cibotii 3g, Radix Paeoniae Alba 3g, Fructus Chaenomelis 5g by weight percentage.
Its preparation process is with embodiment 1.
Instructions of taking: warm water delivery service, early, middle and late each one of every day, two months is a course of treatment.
The Chinese medicine pill made from this prescription carries out clinical treatment observation to 25 patients of femur head necrosis, wherein cures 16 examples, effective 6 examples, invalid or DeGrain 3 examples.
Case: Wang Mingyuan, the man, 41 years old, this patient caused the left side fracture of femoral neck in the traffic accident in May, 2002, drive screw internal fixation, postoperative 10 months, slow fracture union are implemented in the back, on inspection, the patient can not walk, and left lower limb dare not bear a heavy burden, movable back pain, left hip joint function activity is obviously limited, can not squat down, the X-ray sheet shows that fracture line is high-visible, and femoral head has dislocation, the fracture para-position is bad, and femoral head top bone density increases, and is diagnosed as femur head necrosis.In August, 2006 the court treatment, through taking course of treatment of this medicine treatment, clinical symptoms obviously alleviates, and holds up and turns and can walk, left lower extremity can bear a heavy burden, and does not have obvious pain, hip joint function is limited slightly, after take two courses of treatment again, the basic healing.
Embodiment 3
Take by weighing crude drug of the present invention totally 100 gram, wherein Radix Rehmanniae Preparata 9g, Rhizoma Dioscoreae 5g, Fructus Corni 5g, Fructus Lycii 5g, Radix Notoginseng 6g, eupolyphaga 6g, Radix Angelicae Sinensis 9g, Radix Salviae Miltiorrhizae 6g, Flos Carthami 6g, Semen Cuscutae 5g, Rhizoma Alismatis 3g, cattle sunset 5g, the Cortex Eucommiae (stir-fry) 9g, Rhizoma Cibotii 6g, Radix Paeoniae Alba 6g, Fructus Chaenomelis 9g by weight percentage.
Its preparation process is with embodiment 1.
Instructions of taking: warm water delivery service, early, middle and late each one of every day, two months is a course of treatment.
The Chinese medicine pill made from this prescription carries out clinical treatment observation to 24 patients of femur head necrosis, wherein cures 15 examples, effective 5 examples, invalid or DeGrain 4 examples.
Case: Qian Guangshu, the man, 43 years old, pain in the lumbar region often appearred May calendar year 2001, and the bloated dull pain of hip joint acid is done X-ray examination, and the joint is no abnormal, is diagnosed as early stage femur head necrosis.In December, 2006 comes the court's treatment, takes this Drug therapy after course of treatment, and symptom is clearly better, after take two courses of treatment again, clinical symptoms disappears substantially, bone density is normal, bone trabecula shows that evenly function of joint is normal, cures fully.

Claims (2)

1. a Chinese medicine pill for the treatment of femur head necrosis is characterized in that it is to be combined by weight percentage by following material medicine: Radix Rehmanniae Preparata 9-13%, Rhizoma Dioscoreae 5-10%, Fructus Corni 5-10%, Fructus Lycii 5-10%, Radix Notoginseng 3-6%, Eupolyphaga Seu Steleophaga 3-6%, Radix Angelicae Sinensis 5-9%, Radix Salviae Miltiorrhizae 3-6%, Flos Carthami 3-6%, Semen Cuscutae 5-9%, Rhizoma Alismatis 3-6%, Radix Achyranthis Bidentatae 5-9%, Cortex Eucommiae (parched) 5-9%, Rhizoma Cibotii 3-6%, Radix Paeoniae Alba 3-6%, Fructus Chaenomelis 5-9%.
2. the Chinese medicine pill of treatment femur head necrosis according to claim 1 is characterized in that the optimum weight percentage ratio of its material medicine is: Radix Rehmanniae Preparata 11%, Rhizoma Dioscoreae 7%, Fructus Corni 8%, Fructus Lycii 7%, Radix Notoginseng 5%, Eupolyphaga Seu Steleophaga 4%, Radix Angelicae Sinensis 7%, Radix Salviae Miltiorrhizae 5%, Flos Carthami 4%, Semen Cuscutae 7%, Rhizoma Alismatis 4%, Radix Achyranthis Bidentatae 7%, Cortex Eucommiae (parched) 7%, Rhizoma Cibotii 5%, the Radix Paeoniae Alba 5%, Fructus Chaenomelis 7%.
CN2007101155137A 2007-12-14 2007-12-14 Chinese medicine pill for treating hip necrosis Expired - Fee Related CN101199721B (en)

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058717B (en) * 2011-01-25 2012-01-25 郭芫沅 Chinese medicine for treating femoral head necrosis
CN102743440B (en) * 2012-07-30 2014-06-04 刘海凤 Traditional Chinese medicines for treating femoral head necrosis
CN104398662A (en) * 2014-11-05 2015-03-11 崔新明 Traditional Chinese medicine preparation treating femur head necrosis and preparation technology thereof
CN104857239A (en) * 2015-06-01 2015-08-26 郑永智 Traditional Chinese medicine for curing osteonecrosis of femoral head

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CN1319414A (en) * 2001-01-19 2001-10-31 刘军 Medicine for treating hecrosis of femoral head
CN1389252A (en) * 2002-07-24 2003-01-08 李如元 Composite medicine for treating femoral head necrosis
CN1586590A (en) * 2004-07-05 2005-03-02 张华国 Re-creading bolus for reinforcing kidney and generating marrow

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