CN103191315A - Traditional Chinese medicine for treating postmenopausal osteoporosis - Google Patents
Traditional Chinese medicine for treating postmenopausal osteoporosis Download PDFInfo
- Publication number
- CN103191315A CN103191315A CN201310147723XA CN201310147723A CN103191315A CN 103191315 A CN103191315 A CN 103191315A CN 201310147723X A CN201310147723X A CN 201310147723XA CN 201310147723 A CN201310147723 A CN 201310147723A CN 103191315 A CN103191315 A CN 103191315A
- Authority
- CN
- China
- Prior art keywords
- kidney
- traditional chinese
- postmenopausal osteoporosis
- chinese medicine
- deficiency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine for treating postmenopausal osteoporosis. The traditional Chinese medicine is prepared from prepared rehmannia, rhizoma cibotii, herba epimedii, fructus psoraleae, oyster, yam, prepared fleece-flower root, eucommia bark, gastrodia elata, medlar, dogwood fruit pulp, radix achyranthis bidentatae, codonopsis pilosula, donkey-hide gelatin, black sesame, parasitic loranthus, glossy privet and schisandra chinensis. The traditional Chinese medicine is in accordance with the theory of traditional Chinese medicinal differentiation, and is combined with the fact that the occurrence of postmenopausal osteoporosis is related to kidney deficiency and spleen deficiency, wherein kidney deficiency is a main pathogenesis of postmenopausal osteoporosis. From the view of traditional Chinese medicine, kidney governs bones and belongs to water in five elements, liver governs tendons and belongs to wood in five elements, so that deficiency of spleen and kidney means the loss of water and wood, which causes that wood is nourished; and tendons and bones are not tonified to cause postmenopausal osteoporosis with the passing of time. Thus, postmenopausal osteoporosis is treated by tonifying spleen and nourishing liver kidney to achieve the fundamental treatment effects of treating both principal and secondary aspect of disease, and preventing relapse.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly a kind of Chinese medicine for the treatment of postmenopausal osteoporosis.
Background technology
Postmenopausal osteoporosis is to reduce and osseous tissue microstructure degenerative change is feature, the increase of bone fragility, a kind of general metabolic bone disease that is easy to fracture with the bone amount.The women after menopause because the decline of hormonal readiness, the deficiency of calcium and vitamin D intake, the sickness rate of osteoporosis is higher.Mainly showing as stature becomes short or bow-backed, lumbar and back pain, easily fracture etc. takes place, have a strong impact on the life quality of middle aged and aged women, it is all fractured under microtrauma or atraumatic situation easily, bring great misery and high medical expense to the patient, have a strong impact on the quality of life in patient's old age, also brought white elephant to family and society.Consult domestic and foreign literature and find, the treatment to this disease at present lacks medicine safely and effectively.The mode of normal adopt hormone, replenishing the calcium, taking vitamin, moderate exercise is treated, and effect is not ideal enough, and side effect is big, easily recurrence, and the Chinese herbal medicine of some treatment primary disease does not have the effect for the treatment of.
Summary of the invention
The purpose of this invention is to provide and a kind ofly can effect a radical cure postmenopausal osteoporosis and instant effect, short treating period, Chinese medicine that cure rate is high.
For realizing purpose of the present invention, existing according to following technical scheme.This medicine is to be made by following raw materials in weight portion:
Radix Rehmanniae Preparata 25-40 part, Rhizoma Cibotii 15-30 part, Herba Epimedii 15-20 part, Fructus Psoraleae 16-25 part, Concha Ostreae 12-20 part, Rhizoma Dioscoreae 25-30 part, Radix Polygoni Multiflori Preparata 10-20 part, Cortex Eucommiae 12-25 part, Rhizoma Gastrodiae 8-15 part, Fructus Lycii 8-15 part, Fructus Corni 8-15 part, Radix Achyranthis Bidentatae 15-30 part, Radix Codonopsis 15-30 part, Colla Corii Asini 10-15 part, Semen Sesami Nigrum 15-20 part, Herba Taxilli 15-30 part,, Fructus Ligustri Lucidi 12-17 part, Fructus Schisandrae Chinensis 8-15 part.
Medicine of the present invention is according to the theory of Chinese medical discrimination, in conjunction with the generation of primary disease mainly with suffer from a deficiency of the kidney, insufficiency of the spleen relevant, wherein suffer from a deficiency of the kidney be primary disease main diseases because of.On Chinese medicine, kidney governing bones, five elements master's water, liver governing tendons, the five elements belong to wood, the loss of spleen, kidney, namely the disappearance of water, soil causes wood not conserve, and muscles and bones mistake is supported, and with the passing of time brings out primary disease.Therefore, the treatment primary disease is worked as with spleen invigorating, and the rule for the treatment of of nourishing the liver and kidney just can be received the radical cure effect for the treatment of both the principal and secondary aspects of a disease, difficult recurrence.
The side separates:
Radix Rehmanniae Preparata: it is moist to enrich blood; The benefit essence is filled out marrow, cures mainly blood deficiency and yellow complexion; Dizzy cardiopalmus; Menoxenia; Collapse more than; Hepatic and renal YIN deficiency; Hectic fever night sweat; The seminal emission sexual impotence; Infertility; Soreness of the waist and knees.
Rhizoma Cibotii: wind-damp dispelling, invigorating the liver and kidney, strong waist knee joint.Invigorating the liver and kidney, except rheumatism, strong waist foot, sharp joint.Control the back ache, the gonalgia flaccidity of the lower limbs, cold-damp general arthralgia loses and drowns, frequent micturition, seminal emission, leucorrhea.
Herba Epimedii: flavor property return through: hot, sweet, temperature.Return liver, kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.Cure mainly impotence and seminal emission; Cold caused by deficiency is sterile; The frequent micturition incontinence; Dyspnea and cough due to deficiency of the kidney; Soreness of the waist and knees; Rheumatic arthralgia; Hemiplegia; Extremity are meciless.
Fructus Psoraleae: reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha.Main insufficiency of kidney-YANG; Below element deficiency and cold; Chills and pain of the waist and kness; Impotence and seminal emission; Frequent micturition; The enuresis.
Concha Ostreae: medicine for calming liver and calming endopathic wind; Yin-nourishing drug.Convergence, calmness, detoxifcation, analgesic effect are arranged.Modern study, Concha Ostreae contain 80%～95% calcium carbonate, calcium phosphate and calcium sulfate, and contain magnesium, aluminum, silicon and ferrum oxide etc., and its a lot of dosage forms are used for the treatment of the patient of osteoporosis and other calcium deficiency clinically.
Rhizoma Dioscoreae: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Be used for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.
Radix Polygoni Multiflori Preparata: invigorating the liver and kidney, benefiting essence-blood, black beard and hair, turbid blood fat reducing is changed in bone and muscle strengthening.Be used for blood deficiency and yellow complexion, dizzy ear toot, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, hyperlipemia.
The Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.Control the spinal column ache, have rubbish in the body of removing, strengthen the human body cell substance metabolism, prevent that muscle skeleton is aging, the balance human blood-pressure, the decomposer inner cholesterol reduces body fat, recover blood vessel elasticity, the diuresis heat clearing away, broad-spectrum antiseptic, stimulating central nervous system, improve white blood cell count, strengthen remarkable efficacy such as body immunity.
Rhizoma Gastrodiae: sweet flat, return Liver Channel, effect endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral.
Fructus Lycii: nourishing the liver; Nourishing kidney; Lung moistening.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual unclear; Soreness of the waist and knees; Impotence and seminal emission; Cough due to consumptive disease; The taking fluids profusely of quenching one's thirst.
Fructus Corni: liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating controlling nocturnal emission with astringent drugs reducing urination leukorrhagia stopping and only collapse hidroschesis and also have promoting the production of body fluid to quench thirst in addition.Be used for soreness of waist and knee joint dizziness and tinnitus, forgetful emission and spermatorrhea, enuresis frequent micturition.
Radix Achyranthis Bidentatae: invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Ignite (blood) descending; Inducing diuresis for treating stranguria syndrome.
Radix Codonopsis: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Colla Corii Asini: the YIN nourishing of enriching blood, moisturize hemostasis.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough
Semen Sesami Nigrum: invigorating the liver and kidney, benefiting essence-blood, intestine moistening is dry.Be used for dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.
Herba Taxilli: invigorating the liver and kidney; Bone and muscle strengthening; Wind-damp dispelling; Antiabortive.Main soreness of waist and knee joint; A little less than the muscles and bones flaccidity; Limbs are hemiplegia; Rheumatic arthralgia; Head is wrong dizzy; Frequent fetal movement, metrostaxis.Be used for rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and the metrorrhagia warp is many, blood leaking in gestation, frequent fetal movement; Hypertension.
Fructus Ligustri Lucidi: liver and kidney tonifying; Crow must make eye bright.
Fructus Schisandrae Chinensis: astringe the lung, nourishing kidney is promoted the production of body fluid, and receives antiperspirant, arresting seminal emission.
The inventor thinks, postmenopausal osteoporosis is clinical modal primary osteoporosis, and its pathogeny is the postmenopausal estrogen hyposecretion, the effect reduction that makes it promote the calcitonin secretion and suppress the osteoclast stimulating osteoblast, osteoclast is too active, the bone conversion increases, and namely bone formation and bone resorption increase, and bone resorption is greater than bone formation, influence maturation and the bone mineralising of ossein, UCaE increases, and the intestinal calcium absorption descends, and causes osteoporosis.It is remarkable to use estrogen effect aspect the control postmenopausal osteoporosis clinically, but the natural estrogen of using always at present or the derivant of semi-synthetic estrogen all have certain side effect, should not use for a long time.Therefore, can prolonged application, little, the curative effect of side effect preferably Therapeutic Method become the focus that people inquire into.
Epidemiological study also confirmed to suffer from a deficiency of the kidney patient's bone mineral content not only is lower than healthy people of the same age, and is lower than the non-patient who suffers from a deficiency of the kidney.Therefore, insufficiency of the spleen, to suffer from a deficiency of the kidney be the basic reason that osteoporosis takes place.Experiment shows that strengthening spleen, tonifying kidney Chinese medicine has the effect that promotes bone formation and suppress bone resorption, reduction bone turnover rate, raising bone mass.All medicines share in the side, but both tonifying kidney-yins, benefiting essence-blood, the kidney warming sun, bone and muscle strengthening suppresses the osteoclast differentiation, promotes bone formation; Again can spleen invigorating to mend the day after tomorrow, the intestinal calcium absorption is increased, UCaE reduces, and prevents and treats osteoporosis.All medicines share, and can increase bone density, promote bone formation, suppress bone resorption, increase the intestinal calcium absorption, improve symptom, and are evident in efficacy.Originally studies show that the present invention treats postmenopausal osteoporosis and obviously is better than the Western medicine curative effect.
The specific embodiment:
Take by weighing raw material in following ratio
Radix Rehmanniae Preparata 25-40 part, Rhizoma Cibotii 15-30 part, Herba Epimedii 15-20 part, Fructus Psoraleae 16-25 part, Concha Ostreae 12-20 part, Rhizoma Dioscoreae 25-30 part, Radix Polygoni Multiflori Preparata 10-20 part, Cortex Eucommiae 12-25 part, Rhizoma Gastrodiae 8-15 part, Fructus Lycii 8-15 part, Fructus Corni 8-15 part, Radix Achyranthis Bidentatae 15-30 part, Radix Codonopsis 15-30 part, Colla Corii Asini 10-15 part, Semen Sesami Nigrum 15-20 part, Herba Taxilli 15-30 part, Fructus Ligustri Lucidi 12-17 part, Fructus Schisandrae Chinensis 8-15 part.
Preparation method of the present invention is as follows:
1) it is standby, to take by weighing above-mentioned medical material by the prescription proportioning;
2), the pulverizing medicinal materials that takes by weighing 120 mesh sieves excessively, mix homogeneously, flashing is ball then, namely gets Chinese medicine of the present invention.
Instructions of taking: every day 3 times, one after each meal, each 6 grams, warm water delivery service.General 30 days courses for the treatment of.
For showing Chinese medicine of the present invention to the therapeutic effect of postmenopausal osteoporosis, the inventor has carried out clinical observation to 200 routine cases, now reports as follows.
1. data and method
1.1 the whole patients of physical data with reference in January, 1999 China osteoporosis association according to Chinese's skeletal growth development characteristics and large sample bone densitometry result, formulation be suitable for Chinese unified diagnostic criteria.Deducting 2 standard deviations with bone density (BMD) less than M (peak bone density) is osteoporosis.
Collect case 200 examples altogether, age age 〉=45 year old, the women of menopause more than 1 year, (2) are used dual intensity X bone density meter and are checked that other youngster of proximal femur BMD and the same sex is compared minimizing 〉=25%; (3) clinical cardinal symptom be spontaneous lumbago and backache and (or) heavy burden pain, minor symptom is coldness of the body with chills or feverish sensation in the palms and soles, soreness of the waist and knees, tinnitus, indigestion and loss of appetite, abdominal distention, big dry stool or diarrhea with loose stool, frequent micturition, frequent urination at night, light red tongue, tongue are white, CHI-pulse being weak.Get rid of and to suffer from other disease that can influence bone conversion biochemical indicator, or took and to influence the medicine of bone metabolism person, or be associated with serious primary disease such as cardiovascular, liver, kidney and blood system and psychotic.Be divided into 2 groups at random, 100 examples are organized in treatment; Matched group 100 examples.Learn processing by statistics at aspects such as sex, age, the course of disease, the state of an illness for 2 groups, no statistical significance has comparability (P＞0.01).
Carry out the mensuration of main pain symptom scoring and bone density (BMD), Bone Gla protein (BGP), urine pyridol (PYD) before and after the treatment respectively.
Two, Therapeutic Method
Treatment group: oral Chinese medicine of the present invention, day 3 times, each 6 gram, warm water delivery services after meal.
Matched group: oral Caltrate D tablet, (Wyeth Wyeth pharmaceuticals in Jiangsu produces, every 600mg), each 1, every day 2 times; Vitamin D3 500U, every day 2 times is oral.
More than 2 groups be 1 course for the treatment of with 30 days all, observe 1～6 course for the treatment of.
2.1 the total effective rate for the treatment of group as a result 97.0%, the matched group total effective rate relatively has statistical significance (P＜0.01) for 84.0%, 2 group.The treatment group is better than matched group (P＜0.01).This invention has that innovation is advanced, method is simple, convenient and practical, safe and reliable, be easy to characteristics such as popularizations, so has higher clinic popularization and application values, has good social benefit and economic benefit.
Curative effect relatively sees Table 2.1 before and after two groups of patient treatments,
Table 2.1 liang group patient curative effect relatively
Annotate: two groups of curative effects compare, and difference has statistical significance (P＜0.01)
Three, compare with domestic and international similar technology
The present invention relatively has following characteristics with present domestic and international similar technology:
(1) systematicness: problem is from clinical symptoms, pathogenesis, and the mechanism of action of the present invention etc. are inquired into, so comprehensively clinical research, domestic and international less report at present.
Therefore (2) practicality: this problem is clinical research, and selected index is close to clinically, even observation index is also used always by clinical, and cogency is strong, easy operating, this promise the clinical practice using value of this research.
(3) objectivity: most observation index such as bone density, Bone Gla protein, urine pyridol etc. are objective indicator in the problem, and this point is strengthened the reliability of result of study, stability.
(4) advanced, novelty: use the Chinese patent drugs for treatment primary osteoporosis, and combine with the objective determination index, the patient is detected for inquiring into the postmenopausal osteoporosis pathogeny, the at present domestic and international less report of seeing.
Be in the top standard of domestic similar research based on above several aspect the present invention.
Claims (1)
1. a Chinese medicine for the treatment of postmenopausal osteoporosis is characterized in that it is to be made by following raw materials in weight portion: Radix Rehmanniae Preparata 25-40 part, Rhizoma Cibotii 15-30 part, Herba Epimedii 15-20 part, Fructus Psoraleae 16-25 part, Concha Ostreae 12-20 part, Rhizoma Dioscoreae 25-30 part, Radix Polygoni Multiflori Preparata 10-20 part, Cortex Eucommiae 12-25 part, Rhizoma Gastrodiae 8-15 part, Fructus Lycii 8-15 part, Fructus Corni 8-15 part, Radix Achyranthis Bidentatae 15-30 part, Radix Codonopsis 15-30 part, Colla Corii Asini 10-15 part, Semen Sesami Nigrum 15-20 part, Herba Taxilli 15-30 part, Fructus Ligustri Lucidi 12-17 part, Fructus Schisandrae Chinensis 8-15 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310147723.XA CN103191315B (en) | 2013-04-26 | 2013-04-26 | Traditional Chinese medicine for treating postmenopausal osteoporosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310147723.XA CN103191315B (en) | 2013-04-26 | 2013-04-26 | Traditional Chinese medicine for treating postmenopausal osteoporosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103191315A true CN103191315A (en) | 2013-07-10 |
| CN103191315B CN103191315B (en) | 2014-08-20 |
Family
ID=48714248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310147723.XA Expired - Fee Related CN103191315B (en) | 2013-04-26 | 2013-04-26 | Traditional Chinese medicine for treating postmenopausal osteoporosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103191315B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103599327A (en) * | 2013-11-11 | 2014-02-26 | 漯河医学高等专科学校 | Method for preventing and treating primary osteoporosis by using self-made bone strengthening osteoporosis solidifying drink |
| CN104644732A (en) * | 2015-03-10 | 2015-05-27 | 青岛云天生物技术有限公司 | Traditional Chinese medicine preparation for treating liver and kidney deficiency type postmenopausal osteoporosis |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101053608A (en) * | 2006-04-12 | 2007-10-17 | 杨义澄 | 'Gushukang' micropills and its preparation technology |
| CN101757456A (en) * | 2008-10-30 | 2010-06-30 | 葛沛呈 | Medicament composition for treating osteoporosis |
| CN102343027A (en) * | 2011-10-18 | 2012-02-08 | 贵州同济堂制药有限公司 | Xianlinggubao extract, preparation containing same and preparation method thereof |
| CN102526326A (en) * | 2012-02-09 | 2012-07-04 | 刘思娟 | Traditional Chinese medicine for treating postmenopausal osteoporosis and preparation method thereof |
-
2013
- 2013-04-26 CN CN201310147723.XA patent/CN103191315B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101053608A (en) * | 2006-04-12 | 2007-10-17 | 杨义澄 | 'Gushukang' micropills and its preparation technology |
| CN101757456A (en) * | 2008-10-30 | 2010-06-30 | 葛沛呈 | Medicament composition for treating osteoporosis |
| CN102343027A (en) * | 2011-10-18 | 2012-02-08 | 贵州同济堂制药有限公司 | Xianlinggubao extract, preparation containing same and preparation method thereof |
| CN102526326A (en) * | 2012-02-09 | 2012-07-04 | 刘思娟 | Traditional Chinese medicine for treating postmenopausal osteoporosis and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 张银萍等: "实骨饮对绝经后骨质疏松症患者骨形成_破坏指标的影响及疗效观察", 《新中医》, vol. 39, no. 1, 31 January 2007 (2007-01-31), pages 30 - 31 * |
| 徐赫男: "骨质疏松症的中医药研究", 《北京中医药大学学位论文》, 15 August 2005 (2005-08-15), pages 5 - 12 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103599327A (en) * | 2013-11-11 | 2014-02-26 | 漯河医学高等专科学校 | Method for preventing and treating primary osteoporosis by using self-made bone strengthening osteoporosis solidifying drink |
| CN104644732A (en) * | 2015-03-10 | 2015-05-27 | 青岛云天生物技术有限公司 | Traditional Chinese medicine preparation for treating liver and kidney deficiency type postmenopausal osteoporosis |
| CN104644732B (en) * | 2015-03-10 | 2016-04-27 | 吴建国 | A kind of Chinese medicine preparation for the treatment of deficiency of the liver and kindey type postmenopausal osteoporosis |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103191315B (en) | 2014-08-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102872299B (en) | Medicine compound for treating osteoporosis and osteoporosis fracture | |
| CN100423761C (en) | Chinese medicinal preparation for treating fracture, traumatic injury | |
| CN102319332B (en) | Musk bone reunion Chinese medicinal composition | |
| CN103349753A (en) | Traditional Chinese medicine composition for treating kidney deficiency | |
| CN103599404B (en) | A kind of Chinese medicine decoction for the treatment of cervical spondylosis | |
| CN104688932A (en) | Traditional Chinese medicine preparation for postmenopausal osteoporosis and preparation method | |
| CN103191315B (en) | Traditional Chinese medicine for treating postmenopausal osteoporosis | |
| CN101181488A (en) | Chinese medicine composition orally taken for curing osteosporosis | |
| CN103212037B (en) | Traditional Chinese medicine for treating female endocrine disorder and preparation method of traditional Chinese medicine | |
| CN102805830A (en) | Traditional Chinese medicine composite for treating acne | |
| CN101703624B (en) | Chinese medicinal composition for treating ankylosing spondylitis | |
| CN104524524B (en) | Medicine treating osteoporosis and preparing method | |
| CN103751465A (en) | Medicinal liquor for strengthening tendons and eliminating dampness | |
| CN106139015A (en) | A kind of Chinese medicine composition treating neck-shoulder pain, lumbago and leg pain | |
| CN106362066A (en) | Medicinal liquor for treatment of rheumatic and rheumatoid diseases and preparation method thereof | |
| CN102430030B (en) | Chinese medicinal composition for treating bone impediment | |
| CN102125625B (en) | Traditional Chinese medicine for treating ankylosing spondylitis | |
| CN105213905A (en) | A kind of Chinese medicine composition and application thereof preventing and treating postmenopausal osteoporosis | |
| CN105267630A (en) | Traditional Chinese medicine for treating tinnitus | |
| CN103800561A (en) | Traditional Chinese medicine for treating renal hematuria | |
| CN104687137A (en) | Formula and production method of pilose antler brain-strengthening nerves-calming soup material | |
| CN105853782A (en) | Traditional Chinese medicinal composition for treating uterine prolapsed | |
| CN105853668A (en) | Medicament for treating lumbar disc herniation, osteoporosis and cervical spondylosis | |
| CN105213793A (en) | Cure mainly osteoporotic Chinese medicine composition and method for making | |
| CN105616704A (en) | Traditional Chinese medicine preparation for sclerotin healing of osteoporotic fracture |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140820 Termination date: 20150426 |
|
| EXPY | Termination of patent right or utility model |