CN101703624B - Chinese medicinal composition for treating ankylosing spondylitis - Google Patents

Abstract

The invention discloses a Chinese medicinal composition for treating ankylosing spondylitis, which belongs to Chinese medicinal preparations. The Chinese medicinal composition is characterized by preparing from the following raw materials by mass: 10g of glossy privet fruit, 10g of Chinese angelica, 10g of eucommia bark, 15g of giant knotweed rhizome, 20g of spreading hedyotis herb, 15g of honeysuckle flower, 10g of salivia chinensis, 10g of cassia twig, 10g of common monkshood mother root, 10g of lycium bark, 15g of malaytea scurfpea fruit, 20g of cornu cervi, 15g of danshen root, 10g of medicinal indianmulberry Root, 10g of south dodder seed, 10g of common macrocarpium fruit, 10g of white paeony root, 5g of manchurian wildginger, 30g of rehmanniae praeparatum, 20g of pubescent angelica root, 12g of szechuan lovage rhizome, 15g of safflower and 15g of himalayan teasel root. The Chinese medicinal composition for treating the ankylosing spondylitis has the effects of clearing away heat and toxic materials, controlling inflammation and preventing sclerotization and bone joint deformity, and has the characteristics of good stability, no toxic or side effect and the like.

Description

A kind of Chinese medicine composition for the treatment of ankylosing spondylitis

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of ankylosing spondylitis, belong to the field of Chinese medicines.

Background technology

Ankylosing spondylitis is mainly in cold and humid area.The total incidence of China is 0.3%, about 4,500,000 examples, and men and women's property PMR is 10: 1.Sending out the age well is about 16～30 years old, and the primary disease early symptom is waist stiff sense or stiff pain often, stands up at night, get up, or sitting, back, station symptom is particularly evident for a long time, and through after the activity, stiff pain can take a turn for the better.Except that the lumbosacral region joint is subjected to the class, disease can be involved thoracic vertebra and cervical vertebra, shows as stiff and pain in various degree.The visible rigid spine of end-stage patients, hunchback and the disease that disables.Tangible family history can be arranged.Suffer from the early stage patient of ankylosing spondylitis and only feel the intermittent pain of lumbar and back pain, back, buttocks, hip, chest, severe patient spinal column movable function is limited.

Since early stage morbidity intermittent attack, so people are often not enough to the serious consequence understanding that this disease disables, most of patient can not adhere to systematic treating, the state of an illness is developing always, up to deformity.The western medical treatment of ankylosing spondylitis is a first-selection with non-carrier anti-inflammation analgesia medicine, immunosuppressant, unsatisfactory curative effect, and toxic and side effects is big, easily recurrence after the drug withdrawal, though the treatment by Chinese herbs curative effect is fast not as the Western medicine curative effect, than Western medicine stable curative effect, is difficult for recurrence.

Summary of the invention

The objective of the invention is to overcome the deficiency that prior art exists, and a kind of Chinese medicine composition of ankylosing spondylitis is provided, ankylosing spondylitis is had significant curative effect.

The technical scheme that technical solution problem of the present invention is taked is: a kind of Chinese medicine composition for the treatment of ankylosing spondylitis, it is characterized in that, and make by the crude drug of following weight: Fructus Ligustri Lucidi 10 grams, Radix Angelicae Sinensis 10 grams, the Cortex Eucommiae 10 grams, Rhizoma Polygoni Cuspidati 15 grams, Herba Hedyotidis Diffusae 20 grams, Flos Lonicerae 15g, Cortex Moutan 10 grams, Ramulus Cinnamomi 10 grams, Radix Aconiti 10 grams, Cortex Lycii 10 grams, Fructus Psoraleae 15 grams, Cornu Cervi 20 grams, Radix Salviae Miltiorrhizae 15 grams, Radix Morindae Officinalis 10 grams, Semen Cuscutae 10 grams, Fructus Corni 10 grams, the Radix Paeoniae Alba 10 grams, Herba Asari 5 grams, the Radix Rehmanniae 30 grams, Radix Angelicae Pubescentis 20 grams, Rhizoma Chuanxiong 12 grams, Flos Carthami 15 grams, Radix Dipsaci 15 grams.

Preparation and instructions of taking: will go in the marmite after the mixing of above-mentioned raw materials medicine, it is saturating to add blister; Elder generation's intense fire is fried boiling, and with half an hour at a simmer, leaches medicinal liquid again, adds water in the medicinal residues and fries in shallow oil half an hour, leaches medicinal liquid again.Twice medicinal liquid mixes, cools completely, and respectively at half an hour ante cibum morning, takes in two hours after the supper.One month is a course of treatment.Pharmacological action

Fructus Ligustri Lucidi: bitter sweet, flat.Go into liver, kidney channel.Invigorating the liver and kidney, strong waist knee joint.Control interior-heat caused by deficiency of YIN, dizziness, order flower, tinnitus, soreness of the waist and knees, early whitening of beard and hair.Nourishing the liver and kidney, black hair makes eye bright.Be used for vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.

Radix Angelicae Sinensis: Gan Xin, temperature.Go into the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving is moisturized laxation.Control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; The dryness of the intestine dyschezia is heavy after the bloody dysentery; The carbuncle skin ulcer is stolen, injury from falling down.

The Cortex Eucommiae: go into liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, antiabortive.Control the spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is desired to fall, frequent fetal movement, hypertension.

Rhizoma Polygoni Cuspidati: hardship, cold, return liver, lung, gallbladder meridian.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, dampness removing jaundice eliminating, relieving cough and asthma.This product bitter cold is fallen and is let out, and merit is arrogated to oneself removing damp-heat from the liver and the gallbladder, again can the promoting blood circulation to restore menstrual flow pain relieving.

Herba Hedyotidis Diffusae: heat clearing away, dampness removing, detoxifcation.Control dyspnea and cough due to lung-heat, tonsillitis.

Flos Lonicerae: heat clearing away, detoxifcation.Control the epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula.

Cortex Moutan: heat clearing away, removing heat from blood, and blood, repercussive.Control the pathogenic heat attacking blood system in febrile diseases, send out speckle, infantile convulsion is told, is defeated in battle, is had blood in stool, the hectic fever due to YIN-deficiency consumptive fever, and amenorrhea ， mass in the abdomen, carbuncle and ulcer is pounced on damage.

Ramulus Cinnamomi: Xin Gan, temperature.Go into bladder, the heart, lung meridian.The diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.Control exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.

Radix Aconiti: hot, bitter, heat; Very toxic.GUIXIN, liver,kidney,spleen warp.Expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.

Cortex Lycii: heat clearing away, removing heat from blood is controlled asthenia hectic fever night sweat, lung-heat cough with asthma, carbuncle malignant boil.

Fructus Psoraleae: reinforcing the kidney and supporting YANG.Control the cold diarrhea of suffering from a deficiency of the kidney, the enuresis, spermatorrhea, frequent micturition, sexual impotence, chills and pain of the waist and kness, deficiency and coldness is breathed heavily and is coughed.

Cornu Cervi: promoting the circulation of blood, detumescence, kidney tonifying.Control sore swollen toxin, blood stasis is had a pain, asthenia internal injury, lumbar vertebrae pain.

Radix Salviae Miltiorrhizae: hardship is slightly cold; GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, the removing heat from blood mind calming.This product is fallen and promoting the circulation of blood, is apt to into blood system, can qualcomm meridian, blood stasis dispelling stagnates, clearing away heart-fire, removing heat from blood heat, and the will of calming the nerves, remove and throb with fear tiredly, be usually used in obstruction of qi in the chest and cardialgia, menoxenia, skin infection swell and ache, diseases such as insomnia and swelling and pain due to blood stasis.

Radix Morindae Officinalis: Xin Gan, temperature.Go into liver, kidney channel.Kidney-replenishing, strengthening bone and muscle, wind-damp dispelling.Control sexual impotence, few abdomen cold type of pain, incontinence of urine, deficiency-cold of uterus, anemofrigid-damp arthralgia, soreness of waist and knee joint.

Semen Cuscutae: the tonifying liver pain, beneficial marrow makes eye bright.Control soreness of waist and knee joint, quench one's thirst, order is dark.

Fructus Corni: invigorating the liver and kidney, Gu arresting seminal emission gas is collapse.Control soreness of waist and knee joint, dizzy, tinnitus, sexual impotence, seminal emission, frequent micturition, the deficiency of the liver cold and heat, incessant sweating due to debility, the heart shakes scattered pulse.

The Radix Paeoniae Alba: picric acid, cold.Go into liver, spleen channel.Nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, spontaneous sweating, fever due to yin deficiency.

Herba Asari: suffering, temperature.Go into lung, kidney channel.Have effects such as expelling cold and relieving exterior syndrome, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, heat-clearing and toxic substances removing.Control air-cooled headache, nasal sinusitis is laughed somebody to scorn, rheumatic arthralgia.

The Radix Rehmanniae: clearing up internal heat by using drugs of bitter in taste and cold in nature, Gan Hanzhi moistens yin nourishing, for the refrigerant product that moisten, is good at the nourishing YIN and clearing away heat removing heat from blood.The effect clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, intestine moistening.

Radix Angelicae Pubescentis: arduous, temperature.Go into kidney, urinary bladder channel.Dispel the wind, win and wet, cold expelling, pain relieving.Control anemofrigid-damp arthralgia, soreness of waist and knee joint, trick spasm and pain, chronic tracheitis, headache, toothache.

Rhizoma Chuanxiong: acrid in the mouth, temperature.Go into liver, gallbladder meridian.Activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain.Control air-cooled headache and revolve dizzyly, the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.Be used for menoxenia, amenorrhea dysmenorrhea, abdominal mass stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.

Flos Carthami: suffering, temperature.Go into the heart, Liver Channel.Promoting blood circulation to restore menstrual flow, the blood stasis removing pain relieving.Control amenorrhea ， mass in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.

Radix Dipsaci: invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, anal fistula, the carbuncle skin ulcer is swollen.

Traditional medicine is thought, ankylosing spondylitis belongs to categories such as " arthromyodynia ", " kyphosis ", be a kind of in the seronegative spondyloanthropathy, it has the pathological changes of ligament, muscle, skeleton to some extent, the present invention has heat-clearing and toxic substances removing, control inflammation, prevent to ossify, the effect of osteoarthrosis deformity, make osseous tissue repaired, until recovery from illness.Primary disease early, mid-term the patient can not stay any sequela; The fusion of patients with terminal sacroiliac joint bone, intervertebral disc and ligament calcification, ossified make the spinal motion afunction, so its function can not recover fully, and it promptly is clinical cure that the osteoarthrosis surrounding tissue does not develop.So will in time treat,, improve the quality of living to reduce disability rate to greatest extent.

By a large amount of clinical observations, characteristics such as the Chinese medicine composition that the present invention treats ankylosing spondylitis has good stability, have no side effect.

Model case

Example 1, Liu, man, 15 years old.The patient because of right knee pain appears in wound, at that time without normal inspection, took the analgesic commentaries on classics of not getting better in many days voluntarily before 1 year.Recently pain obviously increases the weight of, walk lamely, can not squat down, difficulty in walking, introduce through the acquaintance and to take Chinese medicine composition that the present invention treats ankylosing spondylitis after course of treatment, continue to take medicine after three courses of treatment, the symptom complete obiteration is gone up downstairs normally, and can be engaged in light physical labor, reach clinical cure, follow up a case by regular visits to and do not occur symptom in 1 year.

Example 2, Wang, man, 17 years old.Suffered from ankylosing spondylitis 3 years, rigid spine, hip joint limitation of activity, the difficulty that lies low, knee joint, wrist, shoulder joint swell and ache, the too much tame hospital of once the going to a doctor commentaries on classics of not getting better, and increase the weight of year by year.Take that Chinese medicine composition that the present invention treats ankylosing spondylitis is stiff after three courses of treatment, pain obviously alleviates, joint motion freely, symptom all disappears after after treatment two courses of treatment, does not see recurrence so far more than a year.

Example 3: the week certain, woman, 32 years old.Patient's sitting fatigue, self-induction cervical vertebra swelling and pain, waist is stiff, and the difficulty of bending over goes hospitalize to be diagnosed as ankylosing spondylitis, takes two months symptoms of western medicine and does not feel any better.Through taking Chinese medicine composition that the present invention treats ankylosing spondylitis after course of treatment, the cervical vertebra symptom is clearly better, and rotates flexibly, and the health general state is good, continues to fully recover after two courses of treatment of treatment, follows up a case by regular visits to so far recurrence.

The specific embodiment

Embodiment 1:

Prescription: Fructus Ligustri Lucidi 10 grams, Radix Angelicae Sinensis 10 grams, the Cortex Eucommiae 10 grams, Rhizoma Polygoni Cuspidati 15 grams, Herba Hedyotidis Diffusae 20 grams, Flos Lonicerae 15g, Cortex Moutan 10 grams, Ramulus Cinnamomi 10 grams, Radix Aconiti 10 grams, Cortex Lycii 10 grams, Fructus Psoraleae 15 grams, Cornu Cervi 20 grams, Radix Salviae Miltiorrhizae 15 grams, Herba Epimedii 10 grams, Radix Morindae Officinalis 10 grams,, Semen Cuscutae 10 grams, Fructus Corni 10 grams, the Radix Paeoniae Alba 10 grams, Herba Asari 5 grams, the Radix Rehmanniae 30 grams, Radix Angelicae Pubescentis 20 grams, Rhizoma Chuanxiong 12 grams, Flos Carthami 15 grams, Radix Dipsaci 15 grams.

Preparation and instructions of taking: will go in the marmite after the mixing of above-mentioned raw materials medicine, it is saturating to add blister; Elder generation's intense fire is fried boiling, and with half an hour at a simmer, leaches medicinal liquid again, adds water in the medicinal residues and fries in shallow oil half an hour, leaches medicinal liquid again.Twice medicinal liquid mixes, cools completely, and respectively at half an hour ante cibum morning, takes in two hours after the supper.One month is a course of treatment.

Claims (1)

1. a Chinese medicine composition for the treatment of ankylosing spondylitis is characterized in that, is made by the crude drug of following weight: Fructus Ligustri Lucidi 10 grams, Radix Angelicae Sinensis 10 grams, the Cortex Eucommiae 10 grams, Rhizoma Polygoni Cuspidati 15 grams, Herba Hedyotidis Diffusae 20 grams, Flos Lonicerae 15g, Cortex Moutan 10 grams, Ramulus Cinnamomi 10 grams, Radix Aconiti 10 grams, Cortex Lycii 10 grams, Fructus Psoraleae 15 grams, Cornu Cervi 20 grams, Radix Salviae Miltiorrhizae 15 grams, Radix Morindae Officinalis 10 grams, Semen Cuscutae 10 grams, Fructus Corni 10 grams, the Radix Paeoniae Alba 10 grams, Herba Asari 5 grams, the Radix Rehmanniae 30 grams, Radix Angelicae Pubescentis 20 grams, Rhizoma Chuanxiong 12 grams, Flos Carthami 15 grams, Radix Dipsaci 15 grams.