CN100350964C - Medicine for treating femoral head necrosis and its preparation method - Google Patents
Medicine for treating femoral head necrosis and its preparation method Download PDFInfo
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- CN100350964C CN100350964C CNB2005100432449A CN200510043244A CN100350964C CN 100350964 C CN100350964 C CN 100350964C CN B2005100432449 A CNB2005100432449 A CN B2005100432449A CN 200510043244 A CN200510043244 A CN 200510043244A CN 100350964 C CN100350964 C CN 100350964C
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Abstract
The present invention relates to a medicine for treating femoral head necrosis, which is a medicament prepared by using the following raw materials in certain mixture proportions by weight: hemlock parsley, red peony roots, drynaria, rhizoma corydalis, dried orange peels, curcuma, Chinese teasel roots, mistletoe, mioga gingers, Tougu grass, pubescent angelica roots, dahurian angelica, arisaema cum bile, Chinese atractylodes, clematis roots, astragalus roots, astraolylis lancea formalyrata, radix achyranthis bidentatae, periostracum cicadae, bezoar, human hair, buffalo horns, rhinoceros horns, scorpions, scolopendra and aweto. The preparing method of the medicine for treating femoral head necrosis comprises the following procedures: the bezoar is pulverized; the scorpions, the scolopendra, the aweto and the periostracum cicadae are heated to be scorched and pulverized for standby application; the human hair is heated to be scorched and pulverized for standby application; the buffalo horns and the rhinoceros horns are heated and stir-fried for standby application after pulverized; the rest medicines are soaked in water, heated, decocted and filtered to obtain a liquid medicine which is then heated and evaporated, and the residual solid matter is heated, dried and pulverized for standby application; all the groups of medicinal powder are thoroughly mixed to prepare the medicament in a conventional method. The present invention has the efficacy of blood circulation activation, stasis removal, cold dispersion, dampness removal, meridian and vessel warming and dredging, tendon strengthening and bone generation. The present invention has remarkable effect on the femoral head necrosis.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method thereof, be used for the treatment of femur head necrosis.
Background technology
Osteonecrosis belongs to serious locomotor disease, is common with femur head necrosis wherein, and very harmful to human body, femur head necrosis abbreviates ANFH as, in case suffer from this disease, will lose work capacity and self care ability.
The cause of disease of femur head necrosis:
1, traumatic femur head necrosis: traumatic hip dislocation, fracture of femoral neck, fracture of acetabulum, intertrochanteric fracture, congenital coxa vara, hip joint are dampened, long-term bear a heavy burden etc. of hip joint can make all that only three feeding arteries of femoral head are distorted, drawing-off, pressurized, tears etc. and to cause arterial blood obstructed, cause ischemic necrosis of femoral head.
2, corticosteroid femur head necrosis:
Human body causes fat metabolic disturbance after taking in a large amount of hormones, constitutes fat embolus in the blood vessel around, and fat embolus thromboembolism femoral head tremulous pulse or vein blood vessel cause ischemic necrosis of femoral head.Also have tens kinds of reasons such as ethanol femur head necrosis, decompression characteristic of disease femur head necrosis, hemoglobin characteristic of disease femur head necrosis, but a variety of causes all can draw the femoral head blood vessel embolism, causes ischemic necrosis of femoral head.After the femur head necrosis, cause hip and near surrounding tissue pain thereof, walking is walked lamely, can not be prudent, and hip joint function is limited.
The existing Therapeutic Method of femur head necrosis:
1, restriction is born a heavy burden: lie up, lean on crutches.This method is just prevented a kind of measure of collapse of the femoral head.
2, hydrogenation Ergota, naftidrofuryl, vincamine, nifedipine etc.Only relief of symptoms can not stop PD.
3, electromagnetic stimulation therapy: effect is unreliable.
4, operative treatment: center decompression art, bone grafting operation, vascular bundle implantation, bone transplanting, osteotomy, hip replacement.The expense that is characterized in is big, painful greatly, complication is many, and postoperative effect is also unsatisfactory.
Treat femur head necrosis in sum, people also do not find a kind of convenience, expense is low, misery is little, reliable for effect method.
Summary of the invention
The purpose of this invention is to provide a kind of medicine for the treatment of femur head necrosis, medical expense is low, misery is little, reliable for effect; Its preparation method also is provided.
Technical scheme of the present invention is: a kind of medicine for the treatment of femur head necrosis; it is characterized in that by as the medicament made of following materials of weight proportions, Rhizoma Chuanxiong 5～25; Radix Paeoniae Rubra 5～25; Rhizoma Drynariae 5～50; Rhizoma Corydalis 5～30; Pericarpium Citri Reticulatae 5～40; Radix Curcumae 5～25; Radix Dipsaci 5～60; Herba Taxilli 5～60; Herba Epimedii 5～60; Herba speranskiae tuberculatae 5～40; Radix Angelicae Pubescentis 1～30; the Radix Angelicae Dahuricae 1～30; Arisaema Cum Bile 1～30; Rhizoma Atractylodis 1～30; Radix Clematidis 1～30; the Radix Astragali 1～30; the Rhizoma Atractylodis Macrocephalae 1～30; Radix Achyranthis Bidentatae 1～30; Periostracum Cicadae 1～30; Calculus Bovis 0.1～10; the human hair 1～20; Cornu Bubali 1～30; Cornu rhinocerotis 1～30; Scorpio 1～30; Scolopendra 1～30; Cordyceps 10～50.
Medicament of the present invention is a said dosage form on any pharmaceutics.Clinical dosage form is any in tablet, capsule, granule, spray, ointment, emplastrum or the ointment.
Preparation method is:
Rhizoma Chuanxiong, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Corydalis, Pericarpium Citri Reticulatae, Radix Curcumae, Radix Dipsaci, Herba Taxilli, Herba Epimedii, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Arisaema Cum Bile, Rhizoma Atractylodis, Radix Clematidis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae compositions added in the entry soaked 48 hours, then, heat 100 ℃ fry in shallow oil 4 hours after, filter out medicinal liquid, remove medicinal residues, medicinal liquid is heated to 100 ℃ again and makes water evaporates, remaining solid shape thing, with 105 ℃ of oven dry of solid, shaped thing heating, pulverize the solids after doing stand-by;
Calculus Bovis is pulverized stand-by;
Scorpio, Scolopendra, Cordyceps, Periostracum Cicadae, heating 160-180 ℃ make its zoom, and it is stand-by to pulverize the back;
The human hair is heated to 160-180 ℃, makes its zoom, and is stand-by after pulverizing;
After Cornu Bubali, Cornu rhinocerotis are pulverized, add propagandize hotly to 200-220 ℃ stand-by;
The above-mentioned medicated powder of respectively organizing is fully mixed and makes dosage form according to a conventional method.
In the said method, Calculus Bovis pulverizing, Cornu Bubali and Cornu rhinocerotis are pulverized all at the 120-200 order, and then effect is best.All the other are pulverized by common medicament grinding particle size and get final product.
The adult obeys 1-1.5g every day, divides and takes for three times.
Treatment mechanism:
The osteonecrosis no matter which kind of reason causes, its pathology reason all is a blood vessel embolism, so the key of treatment femur head necrosis is to open blood vessel.
People's skeleton is cellular, in many apertures are arranged, there is blood capillary to pass through in the hole, blood capillary provides blood and oxygen to Organic substances such as the ossein in the skeleton, proteoglycans, work as capillary embolism, when making the skeleton hypoxic-ischemic downright bad, downright bad is not calcium but Organic substances such as ossein, proteoglycan, skeleton has lost Organic substance and has made support, only remaining cellular inorganic calcium.The cellular inorganic calcium that does not have Organic substance to make support can be absorbed by osteoclast, and it is damaged femur head necrosis to occur.
The structure of skeleton is that organic substances such as ossein and proteoglycan are formed cellular framework, and bone has abundant blood capillary, and the more and more sclerotin hardening gradually of depositions such as calcium, phosphorus are arranged on the framework, forms adult's skeleton.Growth change from bone, wanting to grow new bone must make necrotic bone grow Organic substance framework based on ossein and proteoglycan earlier, blood capillary climbs in the framework blood calcium of blood capillary and deposits to and form skeleton on the framework, so repair femur head necrosis, importantly will grow ossein and proteoglycan earlier is main cellular framework, not having the framework blood capillary to grow creeps, there do not have blood vessel also just can't supply with femoral head to be calcareous, do not have the framework blood calcium to deposit nowhere, just can not generate skeleton.
The side separates: Radix Angelicae Sinensis, Rhizoma Corydalis, Scorpio, Scolopendra, Radix Paeoniae Rubra, Rhizoma Chuanxiong, promoting flow of QI and blood blood stasis dispelling; Pericarpium Citri Reticulatae, the circulation of qi promoting of Radix Curcumae dissipating depression of QI; Rhizoma Drynariae, Radix Dipsaci, Herba Taxilli, Herba Epimedii, Cordyceps, Herba speranskiae tuberculatae warming YANG kidney tonifying, bone and muscle strengthening; Radix Clematidis, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Arisaema Cum Bile cold expelling wet, the detumescence pain; The Radix Astragali, Rhizoma Atractylodis Macrocephalae invigorating the spleen to clear away damp pathogen, benefiting vital QI and blood; The Radix Achyranthis Bidentatae priming return through; Periostracum Cicadae, human hair, Cornu Bubali, the Xi Shuijiao bone growth promoting of enriching blood.Full side's the kidney invigorating, replenishing QI and blood, cold expelling are wet, warming the meridian arteries and veins, bone and muscle strengthening.
The present invention has the logical blood effect of very strong broken bolt, makes downright bad femoral head recover blood fortune, and supplies with downright bad necessary ossein, proteoglycan and the blood calcium of femoral head bone growth promoting, makes osteogenesis.
Effect of the present invention is:
1, the broken bolt of blood stasis dispelling is opened blood vessel, makes femoral head blood fortune recover downright bad controlled.
2, supply with femoral head ossein, proteoglycan, calcium and the bone growth promoting factor.
3, easy to use, expense is low, misery is little, and is reliable for effect.
Through clinical trial, the present invention treats the femur head necrosis cure rate and reaches 90%.Now be exemplified below:
Case one: Zhang, man, 36 years old, the necrosis of hormonal bilateral femoral head.Main suit: bilateral hip pain 2 years
History of present illness: once the bilateral hip arthralgia occurs after the fatigue and be the persistence dull pain in June, 2000, and the back of having a rest takes a turn for the better, and identifies oneself due to the fatigue, do not take notice of, abduction occurs in JIUYUE, 2002, in accept orders for repairs or processing moving limited, the difficulty of squatting down promptly arrives the diagnosis and treatment of local hospital, does to be diagnosed as the bilateral femoral head necrosis behind the CT.
History of past illness: because of the chronic dermatitis dermatosis is arranged, have long-time hormone to use history, nothing is drunk, trauma history.
Came institute treatment X-ray film to show on November 30th, 2002, right strand of head become have under the homalocephalus cracked, subside, the even bone trabecula of femoral head density unevenness interrupts, left side femoral head density unevenness is even, and is fuzzy in the bone stricture of vagina.
2 months cracked execution bone resorption of right lateral thigh bone of medication treatment, left side femoral head density is more even, and articular surface is smooth, and the joint space can.On November 14th, 2003, medication treatment 11 months, fl head density is even, and articular surface is smooth, and the joint space is normal, and bone trabecula is clear, and right femoral head density is more even, the necrotic bone basic absorption, the joint space can.
Case history two: Lee, 60 years old, traumatic left side femur head necrosis.The main suit: left hip pain 5 years, walked lamely 2 years.
The discontinuity left side hip arthralgia appears after history of present illness was fallen down during work before 5 years, in local hospital by soft tissue contusion, oral activating blood circulation to dissipate blood stasis class medicine two months, heavy when light during symptom, film making is diagnosed as the left side femur head necrosis before 1 year, existing left hip pain, the difficulty of squatting down.
In June, 1996, institute went to a doctor, left limbus of acetabulum osteosclerosis, and the fl head breadth is flat, the shape irregularity, the crude injustice of articular surface, visible small pieces capsule low density area in the head, bone density is inhomogeneous, and the joint space is narrow.
3 courses of treatment of medication treatment, the sequestrum district absorbs, area of new bone filling, the more preceding rule of articular surface.
Take medicine 6 courses of treatment, fl skull matter density is obviously improved the area of new bone raised growth.
Take medicine 7 courses of treatment, the film making check, the more preceding reparation of fl facies articularis capituli is regular, and bone density is even in the head, and bone trabecula passes through.
Case three: grandson, man, 52 years old, bilateral ethanol type femur head necrosis.The main suit: bilateral hip pain 5 years, increased the weight of 2 years.History of present illness: before 5 years one time morning time-out feel that suddenly the bilateral hip arthralgia is violent, stretch and bend difficulty, can not go to bed, the symptom of controlling oneself after the part massage is slightly improved, and is heavy when light during symptom afterwards, the hip joint limitation of activity occurs before 2 years, can not squat down, promptly find the bilateral femoral head necrosis in the film making of local hospital, the many places treatment is not felt any better, recently my institute.
Promptly toward history; History of drinking history 26 years, every day about 6-8 two, no trauma history.
Come July 8 nineteen ninety institute to go to a doctor, X-ray film shows: right femoral head is slightly flat, hardenability band around the visible capsule low density area in the head, and bone trabecula interrupts, and the fl great wheel is cleaned up clear, and articular surface is smooth, bone trabecula disorder in the head.
Slippery and rapid pulse, yellowish fur is opened Chinese medicine by the present invention and is decocted in water for oral dose, and every day, one pair of treatment was 6 months, and right femur head necrosis bone major part absorbs, the filling of a large amount of freshman bone tissues, bone density is more preceding evenly, fl skull girder marshalling.
The next day of then one pair, treated again 10 months, matter density is even between bifilar bone, and bone trabecula passes through, and repairs drug withdrawal substantially.
Drug withdrawal film making check in a year, bifilar bone bone density is even, and profile is regular.
Case four: patient week certain, man, 50 years old; Hormone+ethanol type bilateral femoral head necrosis.The main suit: the bilateral hip is accompanied bitterly and was walked lamely 6 years.
The patient does not get up at unexpected station after sitting in June, 1999, can stand after the activity, bilateral hip joint discontinuity pain promptly appears afterwards, row is straight walks lamely, pain has and into is prickling sensation, press treatments such as sciatica clothes " YAOTONGNING ", " sciatic nerve ball " and intramuscular injection vitamin B1 three months at local county hospital, heavy when light during symptom, clapping X-ray film when in July, 1992 health check-up examines and is the bilateral femoral head necrosis, give " bone internal decompression " treatment at county hospital, postoperative pain is alleviated, two all postemphasis.With I treated at institute afterwards.
History of past illness has the hobby of drinking, and every day, 2-4 two, and history of drinking history is about 20 years, takes prednisone half a year because of ophthalmic in 1993.Came my institute's treatment on August 21st, 1999, X-ray film shows: on right femoral head is outer capsule sequestrum district is arranged, head subsides, and capsule has sequestrum in the district, and the joint space narrows down, fl skull texture disorder, and it is even that density is owed.
Take medicine after 3 courses of treatment, the more preceding obvious absorption in right femoral head sequestrum district, the filling of area of new bone part, fl skull matter density is more preceding evenly.Treat 9 the film making checks course of treatment, a large amount of freshman bone tissues in sequestrum district, the right femoral head outside generate, and bone density is even, and articular surface is smooth, and fl skull matter density is even, repairs substantially, can drug withdrawal.
Case five: Zheng, woman, 43 years old; After giving birth to before 13 years, deficiency of both QI and blood, dinner is had a cold, the self-induction lumbago and skelalgia, by rheumatism treatment, long-term oral antiinflammatory is painful, prednisone, the state of an illness increase the weight of, and is after the partial closure, heavy when light during the state of an illness, the X line shows: the bilateral femoral head bland necrosis, not good through the many places therapeutic effect, the state of an illness increases the weight of gradually.Hip joint is stiff, it is stiff to be positioned at 18 ℃ of flexings, and left hip joint is anteflexion receives 5 ℃ in 30 ℃, 15 ℃ of abductions, 10 ℃ of internal rotation, after stretch 0 ℃ of right femoral head and slightly be out of shape, the femoral head head has first quarter moon shape necrotic bone, can't take care of oneself, took Chinese herbal medicine orally 1 year in my institute, clinical symptoms is clearly better, and the bilateral hip joint function recovers normally substantially, the recovery from illness of after treatment then.
The specific embodiment
Embodiment one
A kind of medicine for the treatment of femur head necrosis; by the medicament of making as following materials of weight proportions, Rhizoma Chuanxiong 5, Radix Paeoniae Rubra 5, Rhizoma Drynariae 5, Rhizoma Corydalis 5, Pericarpium Citri Reticulatae 5, Radix Curcumae 5, Radix Dipsaci 5, Herba Taxilli 5, Herba Epimedii 5, Herba speranskiae tuberculatae 5, Radix Angelicae Pubescentis 1, the Radix Angelicae Dahuricae 1, Arisaema Cum Bile 1, Rhizoma Atractylodis 1, Radix Clematidis 1, the Radix Astragali 1, the Rhizoma Atractylodis Macrocephalae 1, Radix Achyranthis Bidentatae 1, Periostracum Cicadae 1, Calculus Bovis 0.1, human hair 1, Cornu Bubali 1, Cornu rhinocerotis 1, Scorpio 1, Scolopendra 1, Cordyceps 10.
Preparation method is:
Rhizoma Chuanxiong, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Corydalis, Pericarpium Citri Reticulatae, Radix Curcumae, Radix Dipsaci, Herba Taxilli, Herba Epimedii, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Arisaema Cum Bile, Rhizoma Atractylodis, Radix Clematidis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae compositions added in the entry soaked 48 hours, then, heat 100 ℃ fry in shallow oil 4 hours after, filter out medicinal liquid, remove medicinal residues, medicinal liquid is heated to 100 ℃ again and makes water evaporates, remaining solid shape thing, with 105 ℃ of oven dry of solid, shaped thing heating, pulverize the solids after doing stand-by;
Calculus Bovis is pulverized stand-by;
160 ℃ of Scorpios, Scolopendra, Cordyceps, Periostracum Cicadae, heating make its zoom, and it is stand-by to pulverize the back;
The human hair is heated to 160 ℃, makes its zoom, and is stand-by after pulverizing;
After Cornu Bubali, Cornu rhinocerotis are pulverized, add propagandize hotly to 200 ℃ stand-by;
The above-mentioned medicated powder of respectively organizing is fully mixed and makes capsule according to a conventional method.
In the said method, Calculus Bovis pulverizing, Cornu Bubali and Cornu rhinocerotis are pulverized all at 120 orders, and all the other are pulverized by common medicament grinding particle size and get final product.
Embodiment two
A kind of medicine for the treatment of femur head necrosis; by the medicament of making as following materials of weight proportions, Rhizoma Chuanxiong 25, Radix Paeoniae Rubra 25, Rhizoma Drynariae 50, Rhizoma Corydalis 30, Pericarpium Citri Reticulatae 40, Radix Curcumae 25, Radix Dipsaci 60, Herba Taxilli 60, Herba Epimedii 60, Herba speranskiae tuberculatae 40, Radix Angelicae Pubescentis 30, the Radix Angelicae Dahuricae 30, Arisaema Cum Bile 30, Rhizoma Atractylodis 30, Radix Clematidis 30, the Radix Astragali 30, the Rhizoma Atractylodis Macrocephalae 30, Radix Achyranthis Bidentatae 30, Periostracum Cicadae 30, Calculus Bovis 10, human hair 20, Cornu Bubali 30, Cornu rhinocerotis 30, Scorpio 30, Scolopendra 30, Cordyceps 50.
Preparation method is:
Rhizoma Chuanxiong, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Corydalis, Pericarpium Citri Reticulatae, Radix Curcumae, Radix Dipsaci, Herba Taxilli, Herba Epimedii, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Arisaema Cum Bile, Rhizoma Atractylodis, Radix Clematidis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae compositions added in the entry soaked 48 hours, then, heat 100 ℃ fry in shallow oil 4 hours after, filter out medicinal liquid, remove medicinal residues, medicinal liquid is heated to 100 ℃ again and makes water evaporates, remaining solid shape thing, with 105 ℃ of oven dry of solid, shaped thing heating, pulverize the solids after doing stand-by;
Calculus Bovis is pulverized stand-by;
180 ℃ of Scorpios, Scolopendra, Cordyceps, Periostracum Cicadae, heating make its zoom, and it is stand-by to pulverize the back;
The human hair is heated to 180 ℃, makes its zoom, and is stand-by after pulverizing;
After Cornu Bubali, Cornu rhinocerotis are pulverized, add propagandize hotly to 220 ℃ stand-by;
The above-mentioned medicated powder of respectively organizing is fully mixed and makes granule according to a conventional method.
In the said method, Calculus Bovis pulverizing, Cornu Bubali and Cornu rhinocerotis are pulverized all at 200 orders, and all the other are pulverized by common medicament grinding particle size and get final product.
Embodiment three
A kind of medicine for the treatment of femur head necrosis; by the medicament of making as following materials of weight proportions, Rhizoma Chuanxiong 15, Radix Paeoniae Rubra 18, Rhizoma Drynariae 30, Rhizoma Corydalis 20, Pericarpium Citri Reticulatae 25, Radix Curcumae 15, Radix Dipsaci 40, Herba Taxilli 40, Herba Epimedii 35, Herba speranskiae tuberculatae 25, Radix Angelicae Pubescentis 15, the Radix Angelicae Dahuricae 15, Arisaema Cum Bile 15, Rhizoma Atractylodis 15, Radix Clematidis 15, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 15, Radix Achyranthis Bidentatae 15, Periostracum Cicadae 15, Calculus Bovis 5, human hair 10, Cornu Bubali 15, Cornu rhinocerotis 15, Scorpio 15, Scolopendra 15, Cordyceps 20.
Preparation method is:
Rhizoma Chuanxiong, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Corydalis, Pericarpium Citri Reticulatae, Radix Curcumae, Radix Dipsaci, Herba Taxilli, Herba Epimedii, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Arisaema Cum Bile, Rhizoma Atractylodis, Radix Clematidis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae compositions added in the entry soaked 48 hours, then, heat 100 ℃ fry in shallow oil 4 hours after, filter out medicinal liquid, remove medicinal residues, medicinal liquid is heated to 100 ℃ again and makes water evaporates, remaining solid shape thing, with 105 ℃ of oven dry of solid, shaped thing heating, pulverize the solids after doing stand-by;
Calculus Bovis is pulverized stand-by;
180 ℃ of Scorpios, Scolopendra, Cordyceps, Periostracum Cicadae, heating make its zoom, and it is stand-by to pulverize the back;
The human hair is heated to 170 ℃, makes its zoom, and is stand-by after pulverizing;
After Cornu Bubali, Cornu rhinocerotis are pulverized, add propagandize hotly to 210 ℃ stand-by;
The above-mentioned medicated powder of respectively organizing is fully mixed and makes tablet according to a conventional method.
In the said method, Calculus Bovis pulverizing, Cornu Bubali and Cornu rhinocerotis are pulverized all at 200 orders, and all the other are pulverized by common medicament grinding particle size and get final product.
Claims (6)
1, a kind of medicine for the treatment of femur head necrosis; it is characterized in that; the weight proportion of making the crude drug of effective ingredient is Rhizoma Chuanxiong 5, Radix Paeoniae Rubra 5, Rhizoma Drynariae 5, Rhizoma Corydalis 5, Pericarpium Citri Reticulatae 5, Radix Curcumae 5, Radix Dipsaci 5, Herba Taxilli 5, Herba Epimedii 5, Herba speranskiae tuberculatae 5, Radix Angelicae Pubescentis 1, the Radix Angelicae Dahuricae 1, Arisaema Cum Bile 1, Rhizoma Atractylodis 1, Radix Clematidis 1, the Radix Astragali 1, the Rhizoma Atractylodis Macrocephalae 1, Radix Achyranthis Bidentatae 1, Periostracum Cicadae 1, Calculus Bovis 0.1, human hair 1, Cornu Bubali 1, Cornu rhinocerotis 1, Scorpio 1, Scolopendra 1, Cordyceps 10.
2, prepare the method for the described medicine of claim 1, it is characterized in that, step is:
Rhizoma Chuanxiong, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Corydalis, Pericarpium Citri Reticulatae, Radix Curcumae, Radix Dipsaci, Herba Taxilli, Herba Epimedii, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Arisaema Cum Bile, Rhizoma Atractylodis, Radix Clematidis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae compositions added in the entry soaked 48 hours, then, heat 100 ℃ fry in shallow oil 4 hours after, filter out medicinal liquid, remove medicinal residues, medicinal liquid is heated to 100 ℃ again and makes water evaporates, remaining solid shape thing, with 105 ℃ of oven dry of solid, shaped thing heating, pulverize the solids after doing stand-by;
Calculus Bovis is pulverized stand-by;
160 ℃ of Scorpios, Scolopendra, Cordyceps, Periostracum Cicadae, heating make its zoom, and it is stand-by to pulverize the back;
The human hair is heated to 160 ℃, makes its zoom, and is stand-by after pulverizing;
After Cornu Bubali, Cornu rhinocerotis are pulverized, add propagandize hotly to 200 ℃ stand-by;
The above-mentioned medicated powder of respectively organizing is fully mixed and makes capsule according to a conventional method.
3, a kind of medicine for the treatment of femur head necrosis; it is characterized in that; the weight proportion of making the crude drug of effective ingredient is Rhizoma Chuanxiong 25, Radix Paeoniae Rubra 25, Rhizoma Drynariae 50, Rhizoma Corydalis 30, Pericarpium Citri Reticulatae 40, Radix Curcumae 25, Radix Dipsaci 60, Herba Taxilli 60, Herba Epimedii 60, Herba speranskiae tuberculatae 40, Radix Angelicae Pubescentis 30, the Radix Angelicae Dahuricae 30, Arisaema Cum Bile 30, Rhizoma Atractylodis 30, Radix Clematidis 30, the Radix Astragali 30, the Rhizoma Atractylodis Macrocephalae 30, Radix Achyranthis Bidentatae 30, Periostracum Cicadae 30, Calculus Bovis 10, human hair 20, Cornu Bubali 30, Cornu rhinocerotis 30, Scorpio 30, Scolopendra 30, Cordyceps 50.
4, prepare the method for the described medicine of claim 3, it is characterized in that, step is:
Rhizoma Chuanxiong, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Corydalis, Pericarpium Citri Reticulatae, Radix Curcumae, Radix Dipsaci, Herba Taxilli, Herba Epimedii, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Arisaema Cum Bile, Rhizoma Atractylodis, Radix Clematidis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae compositions added in the entry soaked 48 hours, then, heat 100 ℃ fry in shallow oil 4 hours after, filter out medicinal liquid, remove medicinal residues, medicinal liquid is heated to 100 ℃ again and makes water evaporates, remaining solid shape thing, with 105 ℃ of oven dry of solid, shaped thing heating, pulverize the solids after doing stand-by;
Calculus Bovis is pulverized stand-by;
180 ℃ of Scorpios, Scolopendra, Cordyceps, Periostracum Cicadae, heating make its zoom, and it is stand-by to pulverize the back;
The human hair is heated to 180 ℃, makes its zoom, and is stand-by after pulverizing;
After Cornu Bubali, Cornu rhinocerotis are pulverized, add propagandize hotly to 220 ℃ stand-by;
The above-mentioned medicated powder of respectively organizing is fully mixed and makes granule according to a conventional method.
5, a kind of medicine for the treatment of femur head necrosis; it is characterized in that; the weight proportion of making the crude drug of effective ingredient is Rhizoma Chuanxiong 15, Radix Paeoniae Rubra 18, Rhizoma Drynariae 30, Rhizoma Corydalis 20, Pericarpium Citri Reticulatae 25, Radix Curcumae 15, Radix Dipsaci 40, Herba Taxilli 40, Herba Epimedii 35, Herba speranskiae tuberculatae 25, Radix Angelicae Pubescentis 15, the Radix Angelicae Dahuricae 15, Arisaema Cum Bile 15, Rhizoma Atractylodis 15, Radix Clematidis 15, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 15, Radix Achyranthis Bidentatae 15, Periostracum Cicadae 15, Calculus Bovis 5, human hair 10, Cornu Bubali 15, Cornu rhinocerotis 15, Scorpio 15, Scolopendra 15, Cordyceps 20.
6, prepare the method for the described medicine of claim 5, it is characterized in that, step is:
Rhizoma Chuanxiong, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Corydalis, Pericarpium Citri Reticulatae, Radix Curcumae, Radix Dipsaci, Herba Taxilli, Herba Epimedii, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Arisaema Cum Bile, Rhizoma Atractylodis, Radix Clematidis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae compositions added in the entry soaked 48 hours, then, heat 100 ℃ fry in shallow oil 4 hours after, filter out medicinal liquid, remove medicinal residues, medicinal liquid is heated to 100 ℃ again and makes water evaporates, remaining solid shape thing, with 105 ℃ of oven dry of solid, shaped thing heating, pulverize the solids after doing stand-by;
Calculus Bovis is pulverized stand-by;
180 ℃ of Scorpios, Scolopendra, Cordyceps, Periostracum Cicadae, heating make its zoom, and it is stand-by to pulverize the back;
The human hair is heated to 170 ℃, makes its zoom, and is stand-by after pulverizing;
After Cornu Bubali, Cornu rhinocerotis are pulverized, add propagandize hotly to 210 ℃ stand-by;
The above-mentioned medicated powder of respectively organizing is fully mixed and makes tablet according to a conventional method.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100432449A CN100350964C (en) | 2005-04-15 | 2005-04-15 | Medicine for treating femoral head necrosis and its preparation method |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2005100432449A CN100350964C (en) | 2005-04-15 | 2005-04-15 | Medicine for treating femoral head necrosis and its preparation method |
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| Publication Number | Publication Date |
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| CN1698860A CN1698860A (en) | 2005-11-23 |
| CN100350964C true CN100350964C (en) | 2007-11-28 |
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| Application Number | Title | Priority Date | Filing Date |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055242C (en) * | 1998-06-30 | 2000-08-09 | 钱应敏 | Chinese medicine for curing aseptic necrosis of head of femur |
| CN1150019C (en) * | 2001-01-19 | 2004-05-19 | 刘军 | Medicine for treating hecrosis of femoral head |
-
2005
- 2005-04-15 CN CNB2005100432449A patent/CN100350964C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055242C (en) * | 1998-06-30 | 2000-08-09 | 钱应敏 | Chinese medicine for curing aseptic necrosis of head of femur |
| CN1150019C (en) * | 2001-01-19 | 2004-05-19 | 刘军 | Medicine for treating hecrosis of femoral head |
Non-Patent Citations (2)
| Title |
|---|
| 中医药治疗股骨头坏死概况 吴建华，刘滋雷，尹斌文.中国中医骨伤科，第2卷第1期 1994 * |
| 成人股骨头缺血性坏死的中医药治疗研究 田伟明，王文智，郭海牛.河北中医药学报，第14卷第1期 1999 * |
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| CN1698860A (en) | 2005-11-23 |
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