CN106266204A - One treats osteoporotic medicine - Google Patents

One treats osteoporotic medicine Download PDF

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Publication number
CN106266204A
CN106266204A CN201610944261.8A CN201610944261A CN106266204A CN 106266204 A CN106266204 A CN 106266204A CN 201610944261 A CN201610944261 A CN 201610944261A CN 106266204 A CN106266204 A CN 106266204A
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parts
radix
medicine
angelicae sinensis
osteoporotic medicine
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CN201610944261.8A
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Inventor
王国柱
肖斌
陈志辉
孙超
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SECOND AFFILIATED HOSPITAL OF SHAANXI UNIVERSITY OF CHINESE MEDICINE
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SECOND AFFILIATED HOSPITAL OF SHAANXI UNIVERSITY OF CHINESE MEDICINE
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Priority to CN201610944261.8A priority Critical patent/CN106266204A/en
Publication of CN106266204A publication Critical patent/CN106266204A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A61K36/126—Drynaria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/64—Orobanchaceae (Broom-rape family)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia

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Abstract

The invention discloses one and treat osteoporotic medicine, belong to pharmaceutical technology field, including by the crude drug of following weight parts: the Radix Astragali 10 30 parts, 10 15 parts of Radix Rehmanniae Preparata, Herba Epimedii 10 15 parts, Herba Cistanches 10 15 parts, Semen Cuscutae 10 15 parts, Radix Angelicae Sinensis 5 10 parts, Radix Salviae Miltiorrhizae 5 10 parts, Radix Notoginseng powder 13 parts, Rhizoma Corydalis 10 15 parts, the Radix Paeoniae Alba 5 10 parts, Rhizoma Drynariae 10 15 parts, Radix Achyranthis Bidentatae 10 15 parts, 5 10 parts of Radix Glycyrrhizae.Rapid-action, the short treating period of we, the most repeatedly, side effect is little, treating both the principal and secondary aspects of a disease.

Description

One treats osteoporotic medicine
Technical field
The invention belongs to pharmaceutical technology field, relate to one and treat osteoporotic medicine.
Background technology
Osteoporosis (osteoporosis) is the bone density caused due to many reasons and bone mass decline, the micro-knot of bone Structure destroys, and causes bone fragility to increase, thus is susceptible to the general osteopathia of fracture.Osteoporosis is divided into constitutional and secondary Property two big classes.Primary osteoporosis be divided into again postmenopausal osteoporosis (I type), senile osteoporosis (II type) and Idiopathic osteoporosis (including juvenile) three kinds.Postmenopausal osteoporosis typically occurs in after postmenopausal women 5～10 years In；Senile osteoporosis refers generally to the osteoporosis that old man occurred after 70 years old；And idiopathic osteoporosis occurs mainly in Teenager, the cause of disease is the most not clear.Osteoporosis is in addition to the primary osteoporosis the most relevant with menopause and old age, it is also possible to Caused by multiple disease, referred to as secondary osteoporosis.Osteoporosis is only supplemented to calcium preparation to control for osteoporotic Treatment is far from being enough, need to add according to patient profiles and use medicine.
In prior art, treat osteoporotic Western medicine, easily produce drug resistance, somewhat expensive, in process of clinical application In, find that Western medicine side effect gets more and more, the most not yet find the medicine of a kind of good effect, instant effect.
Summary of the invention
It is an object of the invention to the defect overcoming above-mentioned technology to exist, it is provided that a kind of rapid-action, short treating period, the most repeatedly, Side effect is little, the osteoporotic medicine of the treatment for the treatment of both the principal and secondary aspects of a disease.
Its concrete technical scheme is:
One treats osteoporotic medicine, including by the crude drug of following weight parts: Radix Astragali 10-30 part, Radix Rehmanniae Preparata 10-15 Part, Herba Epimedii 10-15 part, Herba Cistanches 10-15 part, Semen Cuscutae 10-15 part, Radix Angelicae Sinensis 5-10 part, Radix Salviae Miltiorrhizae 5-10 part, Radix Notoginseng powder 1-3 Part, Rhizoma Corydalis 10-15 part, Radix Paeoniae Alba 5-10 part, Rhizoma Drynariae 10-15 part, Radix Achyranthis Bidentatae 10-15 part, Radix Glycyrrhizae 5-10 part.
Preferably, the Radix Astragali 30 parts, 15 parts of Radix Rehmanniae Preparata, Herba Epimedii 15 parts, Herba Cistanches 15 parts, Semen Cuscutae 15 parts, Radix Angelicae Sinensis 10 parts, pellet Join 10 parts, Radix Notoginseng powder 3 parts, Rhizoma Corydalis 15 parts, the Radix Paeoniae Alba 10 parts, Rhizoma Drynariae 15 parts, Radix Achyranthis Bidentatae 15 parts, 10 parts of Radix Glycyrrhizae.
Wherein, the Radix Astragali has benefiting QI for strengthening the superficies, arresting sweating admittedly to take off, holds in the palm skin ulcer granulation promoting, effect of inducing diuresis to remove edema；Radix Rehmanniae Preparata sweet in the mouth tepor matter Profit, YIN nourishing of both having enriched blood, again can vital essence replenishing and marrow benifiting；Herba Epimedii has kidney invigorating and YANG supporting, expelling wind and removing dampness, effect of strong muscle key bone；Herba Cistanches contains The compositions such as abundant alkaloid, crystalline neutral substance, aminoacid, trace element, vitamin, energy kidney-replenishing, benefiting essence-blood, energy The appearance of suppression " yang deficiency " symptom, prevents from losing weight；Semen Cuscutae is convolvulaceous dry mature seed, and property is sweet, warm, returns Kidney, liver, warp, have nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, effect of antidiarrheal；Radix Angelicae Sinensis is to have good replenishing and activating blood Effect；Radix Salviae Miltiorrhizae effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness；Radix Notoginseng has hemostasis, blood circulation promoting and blood stasis dispelling, detumescence Analgesic therapy, strengthening by means of tonics, resisting fatigue, anoxia enduring, defying age, blood fat reducing, blood sugar lowering, raising body's immunity etc. act on；Rhizoma Corydalis Effect of rope and effect: there is promoting blood circulation to remove blood stasis, effect of promoting the circulation of QI to relieve pain, cure mainly headache, lumbago, colicky, bones and muscles pain, dysmenorrhea, Amenorrhea, traumatic injury；Effect of the Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receives antiperspirant；Effect of Rhizoma Drynariae and effect: invigorate blood circulation continuous Wound, the kidney invigorating bone strengthening, treating bone fracture are broken；Effect of Radix Achyranthis Bidentatae: soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis, Note of the ancient Chinese abdominal mass, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain；Radix Glycyrrhizae have QI invigorating strengthening the spleen and middle emergency, Effect of coordinating the actions of various ingredients in a prescription.
The dosage form of the osteoporotic medicine for the treatment of of the present invention is granule, powder, pill, capsule, drop pill, sugar Slurry any one of agent, mixture.
A kind of present invention treats the preparation method of osteoporotic medicine, weighs each according to weight portion of the present invention former Material medicine mixing, is ground into powder, adds suitable adjuvant, and technique is made granule, tablet, powder, pill, capsule, dripped routinely The oral formulations such as pill, syrup, mixture.
Compared with prior art, the invention have the benefit that the medicine of the present invention is pure Chinese medicine, treat osteoporosis institute The soreness of waist that causes, backache, knee joint be soft and hyperosteogeny, has tonifying liver strengthening the spleen, strengthening the tendons and bones, promotes that the broken bone of osteoblast vigor, suppression is thin Effect of cytoactive, rapid-action, short treating period, the most repeatedly, side effect is little, treating both the principal and secondary aspects of a disease.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme is described in more detail.
Embodiment 1
One treats osteoporotic medicine, and its formula is: Radix Astragali 10g, Radix Rehmanniae Preparata 10g, Herba Epimedii 10g, Herba Cistanches 10g, Semen Cuscutae 10g, Radix Angelicae Sinensis 5g, Radix Salviae Miltiorrhizae 5g, Radix Notoginseng powder 1g, Rhizoma Corydalis 10g, Radix Paeoniae Alba 5g, Rhizoma Drynariae 10g, Radix Achyranthis Bidentatae 10g, Radix Glycyrrhizae 5g.
Embodiment 2
One treats osteoporotic medicine, and its formula is: Radix Astragali 20g, Radix Rehmanniae Preparata 12g, Herba Epimedii 12g, Herba Cistanches 12g, Semen Cuscutae 12g, Radix Angelicae Sinensis 8g, Radix Salviae Miltiorrhizae 5-10g, Radix Notoginseng powder 2g, Rhizoma Corydalis 12g, Radix Paeoniae Alba 7g, Rhizoma Drynariae 12g, Radix Achyranthis Bidentatae 12g, Radix Glycyrrhizae 7g。
Embodiment 3
One treats osteoporotic medicine, and its formula is: Radix Astragali 30g, Radix Rehmanniae Preparata 15g, Herba Epimedii 15g, Herba Cistanches 15g, Semen Cuscutae 15g, Radix Angelicae Sinensis 10g, Radix Salviae Miltiorrhizae 10g, Radix Notoginseng powder 3g, Rhizoma Corydalis 15g, Radix Paeoniae Alba 10g, Rhizoma Drynariae 15g, Radix Achyranthis Bidentatae 15g, Radix Glycyrrhizae 10g。
The above, the only present invention preferably detailed description of the invention, protection scope of the present invention is not limited to this, any ripe Know those skilled in the art in the technical scope of present disclosure, the letter of the technical scheme that can become apparent to Altered or equivalence are replaced and are each fallen within protection scope of the present invention.

Claims (2)

1. treat osteoporotic medicine for one kind, it is characterised in that include by the crude drug of following weight parts: include by following heavy The crude drug of amount part: Radix Astragali 10-30 part, Radix Rehmanniae Preparata 10-15 part, Herba Epimedii 10-15 part, Herba Cistanches 10-15 part, Semen Cuscutae 10-15 Part, Radix Angelicae Sinensis 5-10 part, Radix Salviae Miltiorrhizae 5-10 part, Radix Notoginseng powder 1-3 part, Rhizoma Corydalis 10-15 part, Radix Paeoniae Alba 5-10 part, Rhizoma Drynariae 10-15 part, Radix Achyranthis Bidentatae 10-15 part, Radix Glycyrrhizae 5-10 part.
The osteoporotic medicine for the treatment of the most according to claim 1, it is characterised in that the Radix Astragali 30 parts, 15 parts of Radix Rehmanniae Preparata, celestial spirit Spleen 15 parts, Herba Cistanches 15 parts, Semen Cuscutae 15 parts, Radix Angelicae Sinensis 10 parts, Radix Salviae Miltiorrhizae 10 parts, Radix Notoginseng powder 3 parts, Rhizoma Corydalis 15 parts, the Radix Paeoniae Alba 10 parts, Rhizoma Drynariae 15 parts, Radix Achyranthis Bidentatae 15 parts, 10 parts of Radix Glycyrrhizae.
CN201610944261.8A 2016-11-02 2016-11-02 One treats osteoporotic medicine Pending CN106266204A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107823251A (en) * 2017-11-21 2018-03-23 李新梅 A kind of nutrition sclerotin prevents the traditional Chinese medicinal components of osteoporosis
CN108310217A (en) * 2018-03-09 2018-07-24 汪耕郭 Zhuanggu medicinal liquor and production method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王国柱等: "抗疏强骨方治疗肝肾亏虚型原发性骨质疏松症临床观察", 《陕西中医》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107823251A (en) * 2017-11-21 2018-03-23 李新梅 A kind of nutrition sclerotin prevents the traditional Chinese medicinal components of osteoporosis
CN107823251B (en) * 2017-11-21 2020-02-11 李新梅 A Chinese medicinal composition for nourishing bone and preventing osteoporosis
CN108310217A (en) * 2018-03-09 2018-07-24 汪耕郭 Zhuanggu medicinal liquor and production method

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