CN1207911A - Antiviral veterinary medicine injection and its preparation - Google Patents
Antiviral veterinary medicine injection and its preparation Download PDFInfo
- Publication number
- CN1207911A CN1207911A CN 97116309 CN97116309A CN1207911A CN 1207911 A CN1207911 A CN 1207911A CN 97116309 CN97116309 CN 97116309 CN 97116309 A CN97116309 A CN 97116309A CN 1207911 A CN1207911 A CN 1207911A
- Authority
- CN
- China
- Prior art keywords
- filter
- water
- injection
- hours
- standby
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The antiviral veterinary medicine injection is prepared with ginseng, glossy ganoderma, Radix isatidis, tremella and Astragalus membranaceus as material and through crushing, soaking, decoction, filtration to obtain filtrate liquid and other processes. Compared with available technology, it is safe, reliable, non-toxic, harmless and residue-less. The present invention is one ideal medicine for curing chicken pest, hog cholera, distemper and other viral disease of animals.
Description
The present invention relates to a kind of antiviral veterinary medicine injection, relate to a kind of veterinary medicine injection for the treatment of viral diseases such as fowl plague, swine fever, canine distemper, cat distemper and preparation method thereof specifically.
At present, raising day by day along with living standards of the people, people are also more and more higher to the demand of meat, egg, fowl, also promoted greatly developing of animal husbandry thus, yet, domestic animal and poultry but are subjected to the invasion and attack of plague virus such as fowl plague, swine fever constantly in raising, have caused the death of large quantities of domestic animals and poultry, have brought enormous economic loss for the raising cause.
Pestilence such as well-known fowl plague, swine fever are viral disease, virus can only be in living cells growth and breeding, in experiment in vitro antivirus action excellent drug, in the body during experiment since living cells to the selective permeation effect of material, cause the drug level that enters living cells very low, be difficult to reach therapeutic effect.How just can make body produce specific antiviral substance in cell, kill intravital virus, the antiviral function that improves domestic animal is plague virus such as current treatment fowl plague, swine fever and development animal husbandry one the very problem of significant and research.
The object of the present invention is to provide a kind of antiviral veterinary medicine injection and preparation method thereof, utilize the present invention in cell, to synthesize antiviral substance and to suppress virus by rapid excitating organism, and the immune function of body is improved rapidly.
The object of the present invention is achieved like this: it is mainly by Radix Ginseng, Ganoderma, Radix Isatidis, Tremella, the Radix Astragali, through pulverizing, soak, decoct, filter, get filtrate etc., form antiviral veterinary medicine injection of the present invention, it is characterized in that the percentage by weight of component is:
Radix Ginseng 10-30% Ganoderma 10-20%
Radix Isatidis 20-60% Tremella 5-15%
Radix Astragali 15-40%.
The preparation method of antiviral veterinary medicine injection of the present invention is:
1. be purchased the screening and the above-mentioned clean medical material of weighing, processing and fabricating under the dry airy environment of sanitation and hygiene arranged possessing,
2. pulverize
With above-mentioned medical material mixing, be processed into coarse powder,
3. soak
Is 1.5: 1 with the drinking water that meets state health standards by the weight ratio of water and medicine, mix, at room temperature soaked 2 hours,
4. decoct
After the immersion, decoct twice, be fried boiling 30 minutes at every turn,
The weight that adds for the first time water is 5-7 times of former weighing medical material weight, after being fried boiling 30 minutes, filters with the plate filter, gets filtrate, and is standby,
The weight that adds for the second time water is 4-6 times of former weighing medical material weight, after being fried boiling 30 minutes, filters with the plate filter, gets filtrate, and is standby,
5. concentrate
Above-mentioned twice standby filtrate merging decocted, filter, filtrate decompression is concentrated into 1/3 of crude drug in whole weight, and indoor natural cooling is standby
6. precipitate with ethanol is 3 times
With add ethanol 3 times, (contain alcohol amount be respectively 55%, 75%, 83%) of above-mentioned reserve liquid at every turn, left standstill 24 hours at every turn, precipitation, filter, reclaim ethanol each 3 times.
For the first time, it is industrial alcohol 95% or more that above-mentioned reserve liquid is added the alcohol amount of containing, and making it contain that alcohol measures is 55%, left standstill again 24 hours, post precipitation, filtration, filter method is to use the bottle,suction sucking filtration, after reclaiming ethanol, add the injection water, the weight ratio of water for injection and crude drug in whole is 1: 1, indoor natural cooling, after being cooled to room temperature, cold preservation between 4-8 ℃ again, cold preservation 48 hours, standby
For the second time, the precipitate after filtering for the first time added to contain the alcohol amount be industrial alcohol 95% or more, making it contain that alcohol measures is 75%, left standstill again 24 hours, post precipitation, filtration, filter method is to use the bottle,suction sucking filtration, after reclaiming ethanol, add the injection water, the weight ratio of water for injection and crude drug in whole is 1: 1, indoor natural cooling, after being cooled to room temperature, cold preservation between 4-8 ℃ again, cold preservation 48 hours, standby
For the third time, the precipitate after filtering for the second time added to contain the alcohol amount be industrial alcohol 95% or more, making it contain that alcohol measures is 83%, left standstill again 24 hours, post precipitation, filtration, filter method is to use the bottle,suction sucking filtration, after reclaiming ethanol, add the injection water, the weight ratio of water for injection and crude drug in whole is 1: 1, indoor natural cooling, after being cooled to room temperature, cold preservation between 4-8 ℃ again, cold preservation 48 hours, standby
7. adsorption bleaching
Above-mentioned three times reserve liquid is added 0.3% active carbon stirring, be heated to 80 ℃, be 30 minutes heat time heating time, behind the adsorption bleaching, refilter,
8. allocate fine straining
In filtrate, transfer pH value, transfer to 5.5-7.0, add the injection water and contain crude drug in whole 1 gram to every milliliter, be filtered to clarification, promptly reach till the printing opacity with No. 4 filter sticks, with the filtration of filter stick formula filter bulb,
9. fill
With filling machine with above-mentioned liquid medicine filling in the ampere bottle, the ampere bottle was placed in 100 ℃ the sterilization cabinet sterilization 30 minutes, promptly get antiviral veterinary medicine injection of the present invention.But have another name called broad-spectrum high efficacy antiviral veterinary medicine-pestilence health injection.
The present invention compared with prior art, it is safe and reliable, nontoxic, harmless, noresidue, technology is simple, and is with low cost, practical, real is the ideal medicament of viral diseases such as current treatment fowl plague, swine fever, canine distemper, cat distemper.
Below in conjunction with embodiment the present invention is described, the scheme of embodiment described here, do not limit the present invention, one of skill in the art can make improvements and change according to spirit of the present invention, described these improvement and variation all should be considered as within the scope of the invention, and scope and spirit of the present invention are limited by claim.
Embodiment
1. be purchased screening and weigh clean medical material Radix Ginseng 20 grams, Ganoderma 15 grams, Radix Isatidis 40 grams, Tremella 10 grams, the Radix Astragali 15 grams, amount to 100 grams processing and fabricating under the dry airy environment of sanitation and hygiene,
2. pulverize
With above-mentioned medical material mixing, be processed into coarse powder,
3. soak
Mix with the clean medical material of above-mentioned 100 grams with 150 gram tap waters, at room temperature soaked 2 hours,
4. decoct
After the immersion, decoct twice, be fried boiling 30 minutes at every turn,
Add for the first time water 600 grams, after being fried boiling 30 minutes, filter, get filtrate with the plate filter, standby,
Add for the second time water 500 grams, after being fried boiling 30 minutes, filter, get filtrate with the plate filter, standby,
5. concentrate
Above-mentioned twice standby filtrate merging is decocted, filters, filtrate decompression concentrate 33 gram concentrated solutions, indoor natural cooling, standby
6. precipitate with ethanol is 3 times
With add ethanol 3 times, (contain alcohol amount be respectively 55%, 75%, 83%) of above-mentioned reserve liquid at every turn, left standstill 24 hours at every turn, precipitation, filter, reclaim ethanol each 3 times.
For the first time, it is industrial alcohol 95% or more that above-mentioned reserve liquid is added the alcohol amount of containing, and making it contain that alcohol measures is 55%, left standstill again 24 hours, post precipitation, filtration, filter method is to use the bottle,suction sucking filtration, after reclaiming ethanol, add injection water 100 gram, indoor natural cooling, be cooled to room temperature after, cold preservation between 4-8 ℃ again, cold preservation 48 hours, standby
For the second time, the precipitate after filtering for the first time added to contain the alcohol amount be industrial alcohol 95% or more, making it contain that alcohol measures is 75%, left standstill again 24 hours, post precipitation, filtration, filter method is to use the bottle,suction sucking filtration, after reclaiming ethanol, add injection water 100 gram, indoor natural cooling, be cooled to room temperature after, cold preservation between 4-8 ℃ again, cold preservation 48 hours, standby
For the third time, the precipitate after filtering for the second time added to contain the alcohol amount be industrial alcohol 95% or more, making it contain that alcohol measures is 83%, left standstill again 24 hours, post precipitation, filtration, filter method is to use the bottle,suction sucking filtration, after reclaiming ethanol, add injection water 100 gram, indoor natural cooling, be cooled to room temperature after, cold preservation between 4-8 ℃ again, cold preservation 48 hours, standby
7. adsorption bleaching
Above-mentioned three times reserve liquid is added 0.3% active carbon stirring, be heated to 80 ℃, be 30 minutes heat time heating time, behind the adsorption bleaching, refilter,
8. allocate fine straining
In filtrate, transfer pH value, transfer to 5.5-7.0, add the injection water and contain crude drug in whole 1 gram to every milliliter, be filtered to clarification, promptly reach till the printing opacity with No. 4 filter sticks, with the filtration of filter stick formula filter bulb,
9. fill
With filling machine with above-mentioned liquid medicine filling in the ampere bottle, the ampere bottle was placed in 100 ℃ the sterilization cabinet sterilization 30 minutes, promptly get antiviral veterinary medicine injection of the present invention.But have another name called broad-spectrum high efficacy antiviral veterinary medicine-pestilence health injection.
Claims (2)
1, a kind of antiviral veterinary medicine injection, it is mainly by Radix Ginseng, Ganoderma, Radix Isatidis, Tremella, the Radix Astragali, forms through pulverizing, soak, decoct, filter, get filtrate etc., it is characterized in that the percentage by weight of component is:
Radix Ginseng 10-30% Ganoderma 10-20%
Radix Isatidis 20-60% Tremella 5-15%
Radix Astragali 15-40%.
2, antiviral veterinary medicine injection according to claim 1, its feature are that also its preparation method is:
1. be purchased the screening and the above-mentioned clean medical material of weighing, processing and fabricating under the dry airy environment of sanitation and hygiene arranged possessing,
2. pulverize
With above-mentioned medical material mixing, be processed into coarse powder,
3. soak
Is 1.5: 1 with the drinking water that meets state health standards by the weight ratio of water and medicine, mix, at room temperature soaked 2 hours,
4. decoct
After the immersion, decoct twice, be fried boiling 30 minutes at every turn,
The weight that adds for the first time water is 5-7 times of former weighing medical material weight, after being fried boiling 30 minutes, filters with the plate filter, gets filtrate, and is standby,
The weight that adds for the second time water is 4-6 times of former weighing medical material weight, after being fried boiling 30 minutes, filters with the plate filter, gets filtrate, and is standby,
5. concentrate
Above-mentioned twice standby filtrate merging decocted, filter, filtrate decompression is concentrated into 1/3 of crude drug in whole weight, and indoor natural cooling is standby
6. precipitate with ethanol is 3 times
With add ethanol 3 times, (contain alcohol amount be respectively 55%, 75%, 83%) of above-mentioned reserve liquid at every turn, left standstill 24 hours at every turn, precipitation, filter, reclaim ethanol each 3 times.
For the first time, it is industrial alcohol 95% or more that above-mentioned reserve liquid is added the alcohol amount of containing, and making it contain that alcohol measures is 55%, left standstill again 24 hours, post precipitation, filtration, filter method is to use the bottle,suction sucking filtration, after reclaiming ethanol, add the injection water, the weight ratio of water for injection and crude drug in whole is 1: 1, indoor natural cooling, after being cooled to room temperature, cold preservation between 4-8 ℃ again, cold preservation 48 hours, standby
For the second time, the precipitate after filtering for the first time added to contain the alcohol amount be industrial alcohol 95% or more, making it contain that alcohol measures is 75%, left standstill again 24 hours, post precipitation, filtration, filter method is to use the bottle,suction sucking filtration, after reclaiming ethanol, add the injection water, the weight ratio of water for injection and crude drug in whole is 1: 1, indoor natural cooling, after being cooled to room temperature, cold preservation between 4-8 ℃ again, cold preservation 48 hours, standby
For the third time, the precipitate after filtering for the second time added to contain the alcohol amount be industrial alcohol 95% or more, making it contain that alcohol measures is 83%, left standstill again 24 hours, post precipitation, filtration, filter method is to use the bottle,suction sucking filtration, after reclaiming ethanol, add the injection water, the weight ratio of water for injection and crude drug in whole is 1: 1, indoor natural cooling, after being cooled to room temperature, cold preservation between 4-8 ℃ again, cold preservation 48 hours, standby
7. adsorption bleaching
Above-mentioned three times reserve liquid is added 0.3% active carbon stirring, be heated to 80 ℃, be 30 minutes heat time heating time, behind the adsorption bleaching, refilter,
8. allocate fine straining
In filtrate, transfer pH value, transfer to 5.5-7.0, add the injection water and contain crude drug in whole 1 gram to every milliliter, be filtered to clarification, promptly reach till the printing opacity with No. 4 filter sticks, with the filtration of filter stick formula filter bulb,
9. fill
With filling machine with above-mentioned liquid medicine filling in the ampere bottle, the ampere bottle was placed in 100 ℃ the sterilization cabinet sterilization 30 minutes, promptly get antiviral veterinary medicine injection of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97116309A CN1060951C (en) | 1997-08-08 | 1997-08-08 | Antiviral veterinary medicine injection and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97116309A CN1060951C (en) | 1997-08-08 | 1997-08-08 | Antiviral veterinary medicine injection and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1207911A true CN1207911A (en) | 1999-02-17 |
| CN1060951C CN1060951C (en) | 2001-01-24 |
Family
ID=5173754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97116309A Expired - Fee Related CN1060951C (en) | 1997-08-08 | 1997-08-08 | Antiviral veterinary medicine injection and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1060951C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009068872A1 (en) * | 2007-11-27 | 2009-06-04 | Phynova Limited | Antiviral |
| CN104288554A (en) * | 2014-09-30 | 2015-01-21 | 天津瑞贝特科技发展有限公司 | Traditional Chinese veterinary medicine injection for treating infectious bursal disease and preparation method thereof |
| CN104984014A (en) * | 2015-08-04 | 2015-10-21 | 山东新希望六和集团有限公司 | Medicine composition for treating feline panleukopenia and preparation method thereof |
| CN115381862A (en) * | 2022-09-04 | 2022-11-25 | 中国农业科学院蜜蜂研究所 | Preparation for inhibiting crawl bee syndrome caused by bee virus and preparation method and application thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1125618A (en) * | 1995-09-14 | 1996-07-03 | 吉林省生物制品厂生物药品研究所 | Oral liquid for treatment of chicken's Newcastle disease and Fabricius bursa disease |
-
1997
- 1997-08-08 CN CN97116309A patent/CN1060951C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009068872A1 (en) * | 2007-11-27 | 2009-06-04 | Phynova Limited | Antiviral |
| CN104288554A (en) * | 2014-09-30 | 2015-01-21 | 天津瑞贝特科技发展有限公司 | Traditional Chinese veterinary medicine injection for treating infectious bursal disease and preparation method thereof |
| CN104984014A (en) * | 2015-08-04 | 2015-10-21 | 山东新希望六和集团有限公司 | Medicine composition for treating feline panleukopenia and preparation method thereof |
| CN115381862A (en) * | 2022-09-04 | 2022-11-25 | 中国农业科学院蜜蜂研究所 | Preparation for inhibiting crawl bee syndrome caused by bee virus and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1060951C (en) | 2001-01-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109876051A (en) | A kind of gynecological gel and preparation method thereof | |
| CN107173609A (en) | A kind of Chinese herbal feed additive for being used to prevent and treat poultry diarrhea | |
| CN106689807A (en) | Chinese herbal medicine feed with function of improving immunity of ornamental fish | |
| CN1060951C (en) | Antiviral veterinary medicine injection and its preparation | |
| CN101259160B (en) | Compound preparations for treating birdsvirosis and preparation thereof | |
| CA1324084C (en) | Method of extracting a physiological active substance from the husks of pine nuts and anti-contagion medicine made of said extract as principal raw material | |
| CN108524725B (en) | Chlorine dioxide solution for oral administration | |
| CN101194995B (en) | Proprietary Chinese medicine for treating animal virus, bacterium and mix infection | |
| CN1202737C (en) | Accelerant health protection additive of feedstuff using Chinese traditional medicine and its preparation method | |
| KR100819491B1 (en) | Method for the Sulfur Removed Toxic Ingredients | |
| CN105250972A (en) | Traditional Chinese medicine composition for preventing and treating poultry proventriculitis and preparation method and application thereof | |
| KR101812705B1 (en) | A feed additive composition for inhibition of avian influenza and foot-and-mouth diseas | |
| CN1047530C (en) | Efficient disinfectant for prawn and its preparing process | |
| CN101574430A (en) | Chinese medicinal composition for resisting trichomonas columbae disease and method for preparing oral liquid thereof | |
| RU2349332C2 (en) | Method of immunodeficiency prevention for newborn calves | |
| CN1197648A (en) | Shrimp growth promoter | |
| CN1314421C (en) | Cordate houttuynia mixture for preventing and treating livestock bird infectious disease | |
| CN101313978B (en) | Bacillus coli vaccine oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof | |
| CN108079104A (en) | A kind of traditional Chinese medicine oral liquid for treating avian staphylocosis and preparation method thereof | |
| US5241091A (en) | Method of extracting a physiological active substance from the husks of pine nuts and anti-contagion medicine made of said extract as principal raw material | |
| CN101829151B (en) | Preparation method of fly micromolecular active substance with blood fat-reducing function | |
| RU2350080C1 (en) | Vegetative molluscicide | |
| CN1245171C (en) | Yi-E-Jing pill contg. extractives of ant and silk moth for tonifying yang | |
| CN104740490A (en) | Veterinary antiviral traditional Chinese medicine compound oral liquid and preparation method thereof | |
| CN1788781A (en) | Phosphoric acid Chinese traditional medicine compound preparation for preventing and treating bacterial and viral infection of fowl and livestock, and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1023245 Country of ref document: HK |
|
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |