CN120677381A - 检测细胞膜蛋白质的方法 - Google Patents
检测细胞膜蛋白质的方法Info
- Publication number
- CN120677381A CN120677381A CN202480012001.XA CN202480012001A CN120677381A CN 120677381 A CN120677381 A CN 120677381A CN 202480012001 A CN202480012001 A CN 202480012001A CN 120677381 A CN120677381 A CN 120677381A
- Authority
- CN
- China
- Prior art keywords
- cell membrane
- embedding medium
- fixed tissue
- membrane protein
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023050776 | 2023-03-28 | ||
| JP2023-050776 | 2023-03-28 | ||
| PCT/JP2024/012221 WO2024204325A1 (ja) | 2023-03-28 | 2024-03-27 | 細胞膜タンパク質を検出する方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN120677381A true CN120677381A (zh) | 2025-09-19 |
Family
ID=92906670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202480012001.XA Pending CN120677381A (zh) | 2023-03-28 | 2024-03-27 | 检测细胞膜蛋白质的方法 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP4692791A1 (https=) |
| JP (1) | JPWO2024204325A1 (https=) |
| KR (1) | KR20250166224A (https=) |
| CN (1) | CN120677381A (https=) |
| AU (1) | AU2024242849A1 (https=) |
| MX (1) | MX2025010250A (https=) |
| WO (1) | WO2024204325A1 (https=) |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE349010T1 (de) | 2003-02-27 | 2007-01-15 | Dako Denmark As | Standard für immunhistochemie, immunzytologie und molekulare zytogenetika |
| US20060252025A1 (en) * | 2004-12-30 | 2006-11-09 | Ventana Medical Systems, Inc. | Low temperature deparaffinization |
| CA2661669C (en) * | 2006-08-23 | 2017-02-14 | Korea Research Institute Of Bioscience And Biotechnology | A pharmaceutical composition for treating cholangiocarcinoma, a method for inhibiting growth or invasion of cholangiocarcinoma and a method for treating cholangniocarcinoma |
| BRPI0911926A2 (pt) | 2008-08-05 | 2020-08-18 | Toray Industries, Inc | composições farmacêuticas, anticorpos e usos de um anticorpo ou um fragmento do mesmo. |
| MX2011001445A (es) | 2008-08-05 | 2011-04-05 | Toray Industries | Metodo para detectar cancer. |
| US8067241B2 (en) | 2009-08-26 | 2011-11-29 | General Electric Company | Method and apparatus for antigen retrieval process |
| DK2532366T3 (da) | 2010-02-04 | 2017-01-02 | Toray Industries | Farmaceutisk sammensætning til behandling og/eller forebyggelse af cancer |
| CA2788545C (en) | 2010-02-04 | 2019-03-26 | Toray Industries, Inc. | Pharmaceutical composition for treating and/or preventing cancer |
| US9115200B2 (en) | 2010-02-04 | 2015-08-25 | Toray Industries, Inc. | Pharmaceutical composition for treating cancer using a monoclonal antibody having immunological reactivity with CAPRIN-1 |
| HUE040012T2 (hu) | 2010-02-04 | 2019-02-28 | Toray Industries | Gyógyászati ágens rák kezelésére és/vagy megelõzésére |
| RU2603742C2 (ru) | 2010-02-04 | 2016-11-27 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики рака |
| DK2532680T3 (da) | 2010-02-04 | 2015-07-20 | Toray Industries | Medicinsk sammensætning til behandling og/eller forebyggelse af cancer |
| US9181348B2 (en) | 2011-08-04 | 2015-11-10 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| PT2740796T (pt) | 2011-08-04 | 2017-07-26 | Toray Industries | Composição farmacêutica para o tratamento e/ou profilaxia de cancro |
| PT2740489T (pt) | 2011-08-04 | 2017-01-10 | Toray Industries | Composição farmacêutica para o tratamento e/ou a prevenção do cancro pancreático |
| RU2595400C2 (ru) | 2011-08-04 | 2016-08-27 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики злокачественной опухоли |
| PL2740793T3 (pl) | 2011-08-04 | 2018-04-30 | Toray Industries, Inc. | Kompozycja leku do leczenia i/lub zapobiegania nowotworowi |
| EP2740794B1 (en) | 2011-08-04 | 2018-04-04 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| US9260513B2 (en) | 2012-02-21 | 2016-02-16 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| ES2739612T3 (es) | 2012-02-21 | 2020-02-03 | Toray Industries | Composición farmacéutica para el tratamiento de cáncer |
| BR112014021103A2 (pt) | 2012-02-21 | 2019-10-15 | Toray Industries, Inc | Anticorpo, composição farmacêutica, droga de combinação, dna, método de tratamento e uso de anticorpo |
| WO2013125654A1 (ja) | 2012-02-21 | 2013-08-29 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| WO2013147176A1 (ja) | 2012-03-30 | 2013-10-03 | 東レ株式会社 | 胆嚢癌の治療及び／又は予防用医薬組成物 |
| JP6107654B2 (ja) | 2012-03-30 | 2017-04-05 | 東レ株式会社 | 肝臓癌の治療及び／又は予防用医薬組成物 |
| PL2876447T3 (pl) * | 2012-07-19 | 2020-05-18 | Toray Industries, Inc. | Sposób wykrywania nowotworu |
| AU2014303375B2 (en) | 2013-08-09 | 2019-07-04 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| CN109890417A (zh) | 2016-10-28 | 2019-06-14 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
| AU2019242520B2 (en) | 2018-03-30 | 2026-02-26 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| US20220073641A1 (en) * | 2018-12-28 | 2022-03-10 | The University Of Tokyo | Fusion protein of antibody that recognizes cancer cells and mutant streptavidin |
| JP2023050776A (ja) | 2021-09-30 | 2023-04-11 | パナソニックＩｐマネジメント株式会社 | パネル装置 |
-
2024
- 2024-03-27 WO PCT/JP2024/012221 patent/WO2024204325A1/ja not_active Ceased
- 2024-03-27 CN CN202480012001.XA patent/CN120677381A/zh active Pending
- 2024-03-27 AU AU2024242849A patent/AU2024242849A1/en active Pending
- 2024-03-27 EP EP24780431.3A patent/EP4692791A1/en active Pending
- 2024-03-27 KR KR1020257034502A patent/KR20250166224A/ko active Pending
- 2024-03-27 JP JP2024526940A patent/JPWO2024204325A1/ja active Pending
-
2025
- 2025-08-29 MX MX2025010250A patent/MX2025010250A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4692791A1 (en) | 2026-02-11 |
| KR20250166224A (ko) | 2025-11-27 |
| AU2024242849A1 (en) | 2025-09-25 |
| JPWO2024204325A1 (https=) | 2024-10-03 |
| WO2024204325A1 (ja) | 2024-10-03 |
| MX2025010250A (es) | 2025-10-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2744836C2 (ru) | Прямой иммуногистохимический анализ | |
| AU2010311540B9 (en) | PODXL protein in colorectal cancer | |
| JP5767116B2 (ja) | 白金に基づく治療に対する応答の予測 | |
| JP5301630B2 (ja) | 結腸直腸癌のためのマーカーとしてのタンパク質ｓａｔｂ２の使用 | |
| US20110091384A1 (en) | Biomarker for identification of melanoma tumor cells | |
| EP2054443B1 (en) | Antibodies to an epitope of agr2, assays and hybridomas | |
| CN104603620A (zh) | 使用间变性淋巴瘤激酶(alk)作为标志物鉴定治疗响应性非小细胞肺癌的方法 | |
| CN103403550A (zh) | 使用与braf v600e特异性结合的抗体诊断癌症的工具和方法 | |
| JP2012501440A (ja) | 内分泌処置予測因子としてのａｎｌｎタンパク質 | |
| US20210048432A1 (en) | Direct immunohistochemistry and immunocytochemistry methods | |
| WO2010066252A1 (en) | Method for evaluating pre-treatment | |
| CN120677381A (zh) | 检测细胞膜蛋白质的方法 | |
| US20120040361A1 (en) | Methods and compositions for detection of lethal system and uses thereof | |
| CA3285382A1 (en) | Method for detecting cell membrane protein | |
| JP2013096783A (ja) | 肺腺癌を判定するためのデータ検出方法、診断薬、及び診断用キット | |
| KR101567053B1 (ko) | 방사선 피폭에 의한 간 손상 예측용 바이오마커 및 그 예측방법 | |
| US20140113385A1 (en) | Compositions and Methods for Identifying Single Antigens or Other Molecules in Cell Preparations | |
| WO2007103538A2 (en) | Methods of multiple antibody labeling and uses thereof | |
| HK1166371B (en) | Prediction of response to platinum-based therapy | |
| CN104871002A (zh) | 用于检测前列腺基底细胞的方法 | |
| WO2006059712A1 (ja) | ヒトステロイドサルファターゼに結合するモノクローナル抗体 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |