CN1200291A - 一种治疗糖尿病的中草药物 - Google Patents
一种治疗糖尿病的中草药物 Download PDFInfo
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Abstract
本发明提供了一种治疗糖尿病的中草药制剂,它是下列原料制成的中药制剂:石膏、天花粉、黄芪、生地黄、玉米须、石斛、玄参、丹参、葛根、山药、枸杞子、地骨皮、知母、玉竹、乌梅、麦门冬、黄精、黄柏、五味子、山茱萸、甘草、猪、鸡、鸭胰各一条。经100余例临床验证,疗效好,其治愈率可达85%,有效率100%,显效率95%,无副作用。
Description
本发明涉及治疗糖尿病的药物,具体是一种治疗糖尿病的中草药制剂。
糖尿病是一组病因和发病机理尚未完全明了的内分泌代谢疾病,而以高血糖为其主要标志。因胰岛素分泌绝对或相对不足以及靶细胞对胰岛素敏感性降低,引起糖蛋白质、脂肪及继发的水、电解质代谢紊乱,临床上出现烦渴、多尿、多饮、多食、疲乏、消瘦等表现,严重时可发生酮症酸中毒或其它类型急性代谢紊乱,常见合并症有急性感染、肺结核、动脉粥样硬化、肾及视网膜微血管病变及神经病变等。糖尿病是影响人民健康和生命的常见病和多发病,一般终身不愈,并发症严重。其临床表现可归纳为三方面:(1)代谢紊乱综合症。胰岛素分泌绝对或相对不足是导致代谢紊乱的主要因素,同时,胰高血糖素分泌增高也加重了代谢紊乱的发展,患者表现为烦渴、多饮、多尿、多食、消瘦及疲乏等症状。(2)糖尿病慢性病变。常见的是动脉粥样硬化性心及脑血管疾病、糖尿病性肾病、神经系统病变、眼部病变等多种并发症,其发生、发展与糖尿病发病年龄、病程长短、代谢紊乱程度和治疗控制程度相关。(3)感染等合并症。如疖痛等皮肤化脓性感染、肺结核、泌尿系感染、胆囊炎等合并症。由于对糖尿病的病因和发病机理尚未充分了解,对其防治尚缺少有效的方法。治疗上应强调早期治疗,长期治疗及治疗措施的个体化,采取体力锻炼、饮食治疗、降糖药物和宣传教育等综合治疗措施。糖尿病的药物治疗,主要包括口服降糖药和胰岛素治疗。口服降糖药有两类—磺脲类和双胍类。(1)磺脲类药物直接刺激胰岛B细胞释放胰岛素改善II型糖尿病患者的胰岛素复体及/或复体后缺陷,从而增强靶组织细胞对胰岛素的敏感性。目前,临床上常用药有甲苯磺丁脲、乙酰磺环已脲、优降糖、吡磺环已脲、甲磺吡脲等。此类药物主要适用于用饮食治疗不能获得良好临床和生化控制的II型糖尿病。但此类药物长期服用,可产生一定毒副作用,如诱发低血糖反应,停药后仍反复低血糖发作、恶心呕吐、消化不良、胆汁郁滞性黄疸和肝功能受损,造血系统副作用,如白细胞减少、粒细胞缺乏、再障、溶血性贫血、皮肤搔痒、皮诊及光敏性皮炎等。(2)双胍类药物可促进肌肉等外周组织摄取葡萄糖,加速无氧糖酵解,抑制葡萄糖异生、抑制或延缓葡萄糖在胃肠道吸收。适用于症状轻、体型肥胖的II型糖尿病,常用药物有二甲双胍(降糖片)、苯乙双胍(降糖灵)等,其常见副作用有胃肠道反应,皮肤过敏反应,如发生肝功能不全,低血容量休克或心衰等缺氧情况,可能诱发乳酸性酸中毒,因此有些国家已严格限制使用双胍类药物。(3)胰岛素治疗。主要用于I型糖尿病、II型糖尿病经饮食及口服降糖药治疗未获得良好控制者,糖尿病急性代谢紊乱、酮症酸中毒、高渗性昏迷、乳酸性中毒伴高血糖、合并重症感染和消耗性疾病,伴有外科病于施行大手术前后,糖尿病包括妊娠糖尿病患者妊娠和分娩时。使用胰岛素的常见副作用有胰岛素剂量过大及饮食失调可致低血糖反应,胰岛过敏,脂肪营养不良;注射部位皮下脂肪萎缩或增生,胰岛素治疗初期可因钠潴留作用发生轻度水肿。目前也有治疗糖尿病的中草药物,但疗效较差。
本发明的目的是提供一种治疗糖尿病的中草药制剂,其显效率、治愈率均较高,且无副作用,造价较低。
本发明的目的是这样实现的:一种治疗糖尿病的中草药制剂,其特征在于它是由下列重量配比的原料按常规制剂方法制成的中药制剂:
石膏 280-320份 天花粉 270-330份
黄芪 270-320份 生地黄 270-320份
玉米须 290-310份 石斛 270-330份
玄参 80-120份 丹参 90-110份
葛根 90-120份 山药 90-110份
枸杞子 80-120份 地骨皮 100-110份
知母 90-120份 玉竹 280-320份
乌梅 80-120份 麦门冬 90-110份
黄精 80-120份 黄柏 80-120份
五味子 90-120份 山茱萸 90-110份
甘草 90-120份 猪、鸡、鸭胰各一条。
上述的中药制剂,可以是汤剂、冲剂、粉剂、胶囊、口服液或丸剂等。
本发明的方剂是应用祖国优秀的传统医学理论创制而成。本发明的药理分析是:通过中草药调节机体各脏器,且对胰岛有激活作用,能促进胰岛素的再生,增强胰岛细胞的分泌机能,调节体内糖的代谢,改善血流运行,增强肌体免疫力,提高人体碳水化合物的耐受量,达到活血降糖、滋阴、生津、健脾益肾、降低血糖、尿糖的作用,无毒副作用。
以下是本发明的实施例配比表(单位:g):
类 | 实施例 | 类 | 实施例 | ||||||
1 | 2 | 3 | 4 | 1 | 2 | 3 | 4 | ||
石膏天花粉黄芪生地黄玉米须石斛玄参丹参葛根山药枸杞子 | 28027027027029033080909011080 | 30029028029030031010095100100100 | 31031029030030529011010011095110 | 32033031032031027012011012090120 | 地骨皮知母玉竹乌梅麦门冬黄精黄柏五味子山茱萸甘草猪鸡鸭胰 | 100100280809012080909090各1 | 105902909010010010010095100各1 | 10511030010510590110110100110各1 | 11012032012011080120120110120各1 |
用其制成的粉剂,每次服用量为3-7g,日服3次。经过108例糖尿病人临床验证,其统计规律如下表:
临床人数 | 有效 | 占% | 显效 | 占% | 治愈 | 占% |
108人 | 108人 | 100 | 102人 | 95 | 91人 | 85 |
注:化验指标均正常,不服药后亦无复发,为治愈。
以下例举几个病历如下:
1、张秀琴,女,59岁,衡水市牛佐村人,得病5-6年,用药降糖灵、双降糖胶囊、消渴丸,症状四肢无力,小便次数多,喝水多,肉皮淡痒。1997年元月1号通过服用本药,1个疗程20天,四肢有劲,小便正常,喝水也少了。97年元月20号,又服用一个疗程,20用完后化验结果一切正常,至今未复发。
2、张贵岭,男,64岁,邢台市,清河县新二村三十六巷9号,前用药降糖灵,每天早2片晚3片,血糖9.31。1997年2月3号,连服本药2个疗程,40天,化验血糖、尿糖一切正常。至今未复发。
3、刘文英,女,40岁,衡水枣强县城关镇北店村人,得病8年,眼看不清,看什么都有黑影,原用降糖药,长年服用,效果一般。1996年9月7号用本药一个疗程,眼看东西有好转继续用药一个疗程,眼看东西,没黑影了。现什么药也不用,一切正常。
4、杜书芬,女,60岁,深县乔屯乡东大张村人,1984年得糖尿病在衡水地区医院化验,血糖10.7,尿血4个+号,口干,四肢无力,下肢肿,用药克糖平,消渴丸,长年服用。1996年6月10号,用本药20天,四肢有力,口不干了,下肢肿也不怎么肿了,尿糖剩2个+号,1996年7月1号,又取20天,药用完后,化验血糖6.7,+号没了,至今一切正常。
Claims (1)
1、一种治疗糖尿病的中草药制剂,其特征在于它是由下列重量配比的原料按常规制剂方法制成的中药制剂:
石膏 280-320份 天花粉 270-330份
黄芪 270-320份 生地黄 270-320份
玉米须 290-310份 石斛 270-330份
玄参 80-120份 丹参 90-110份
葛根 90-120份 山药 90-110份
枸杞子 80-120份 地骨皮 100-110份
知母 90-120份 玉竹 280-320份
乌梅 80-120份 麦门冬 90-110份
黄精 80-120份 黄柏 80-120份
五味子 90-120份 山茱萸 90-110份
甘草 90-120份 猪、鸡、鸭胰各一条。
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