CN1199611A - Calcium replenishing chewing tablet - Google Patents
Calcium replenishing chewing tablet Download PDFInfo
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- CN1199611A CN1199611A CN 97112058 CN97112058A CN1199611A CN 1199611 A CN1199611 A CN 1199611A CN 97112058 CN97112058 CN 97112058 CN 97112058 A CN97112058 A CN 97112058A CN 1199611 A CN1199611 A CN 1199611A
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- calcium
- replenishing
- pigment
- binding agent
- chewing tablet
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Abstract
Calcium replenishing chewing tablet contains calcium citrate, mannitol, glucose, citric acid, aspartame, starch, adhesive, pigment, lemon essence, menthol and magnesium stearate. It comes in different types, including adult one, pregnant and nursing woman one and children one, with slightly changed composition. It is easy to dissolve and absorb and contains no sugar and has no special smell.
Description
The present invention relates to a kind of calcium replenishing chewing tablet, particularly a kind of quid tablet that contains calcium citrate.
Calcium is the maximum inorganic elements of people's in-vivo content, almost participate in all normal physiological activities of human body, adult's calcium deficiency and cause the fracture, produce chronic lambago and skelalgia, arteriosclerosis, hypertension etc., old people's calcium deficiency and cause alopecia and fatigue, lumbago and backache, hypomnesis, senile dementia, osteoporosis etc. and quicken old and feeble.Long-term low blood calcium extremely makes tooth, skeleton development bad, and rickets, osteomalacia are taken place.
For keeping and promoting national health, the standard of calcium amount has been recommended to take in by many countries to its people.1994, the state-run clinic of the U.S. has recommended optimal day to take the photograph the calcium amount according to achievement in research in recent years, 1-5 year is 800mg, 6-10 year is 800-1000mg, 11-24 year is 1200-1500mg, and 25-50 year women is 1000mg, and the postmenopausal women who accepts estrin treatment is 1000mg, 25-65 year man is 1000mg, and the old people who surpasses 65 years old is 1500mg.
Since people recognize the danger of low calcium absorption, the calcium salt that original amount of replenishing the calcium is lower can not be applicable to the prevention and the treatment of general calcium deficiency, for example: the calcium hydrogen phosphate of calcium gluconate, calcium lactate and less usefulness, the absorption rate of these calcium additives is all undesirable, therefore, be necessary to provide a kind of new replenishing the calcium to chew sheet.
The object of the invention provides the calcium replenishing chewing tablet of a kind of easy dissolving, absorption, and this quid tablet free from extraneous odour does not contain sugar, and it is edible to be suitable for child, pregnant food in one's mouth women, adult.
For achieving the above object, the present invention by the following technical solutions: this calcium replenishing chewing tablet comprises following component, and the weight percentage of each component is respectively:
Calcium citrate 45-63%
Mannitol 25-35%
Glucose 5-10%
Citric acid 1.2-3.0%
Aspartame 0.5-1.5%
Starch 1-3.2%
Binding agent 0.7-1.2%
Pigment 0.002-0.003%
Fructus Citri Limoniae essence 0.5-1.0%
Mentholum 0.01-0.02%
Magnesium stearate 0.3-1%
A kind of replenishing the calcium chewed buccal tablet and comprised following component, and wherein the weight percentage of each component is respectively:
Whole milk powder 28-35%
Calcium citrate 35-50%
Mannitol 10-20%
Glucose 5-10%
Citric acid 1.2-3.0%
Aspartame 0.5-1.5%
Starch 1-3.2%
Binding agent 0.7-1.2%
Pigment 0.002-0.003%
Milk powdered flavor 0.5-1.0%
Magnesium stearate 0.3-1%
The effect of each component is in the prescription: calcium citrate: calcium is provided; Mannitol: cooling feeling is arranged when orally-dissolvable, and pleasantly sweet, be specially adapted to chewable tablet; Glucose: as filler, and flavoring, work with starch one, increase the cohesive force of starch; Starch: filler; Aspartame (aspartoyl phenylalanine potassium fat has another name called sweetener): flavoring, low in calories, do not decay tooth; Food coloring: coloring agent, can adopt any in lemon yellow, light green, the amaranth; Sodium carboxymethyl cellulose: binding agent, also can adopt other binding agents; Magnesium stearate: lubricant; Edible essence, for example Fructus Citri Limoniae essence; Flavoring tool faint scent improves mouthfeel.
The chewable tablet that above-mentioned component can be used for being grown up or pregnant food in one's mouth phase women eats, but pregnant food in one's mouth phase women use chew in can adopt the citric acid (the high limit of for example peek value) of more amount.
In the prescription of another type, be the chewable tablet of replenishing the calcium equally, but,, correspondingly reduce the consumption of calcium citrate, mannitol, and use Fructus Citri Limoniae essence instead the milk powdered flavor so can increase whole milk powder in the prescription because of being used for the child.
Calcium replenishing chewing tablet processing technique provided by the invention is: calcium citrate is pulverized; Again all the other raw materials (compound) are pulverized; The preparation binding agent; The above-mentioned calcium citrate of having pulverized, compound are placed granulator, add binding agent and granulation; Drying again, granulate, total mixing adds the female powder of essence when always mixing, again with dried granule and lubricant for example the magnesium stearate mixed pressuring plate form.
Embodiment 1:
1, pretreatment of raw material:
1a: drying, look the raw material drying degree, take the circumstances into consideration dry.
1b takes by weighing calcium citrate 5kg, places Universalpulverizer to pulverize, and screen cloth is 80 orders.
Take by weighing mannitol 3.23kg, glucose 0.85kg, citric acid 0.26kg, aspartame 0.13kg, starch 0.3kg mix homogeneously adds and pulverizes (screen cloth is 80 orders) in the Universalpulverizer.
The preparation of 2 binding agents: binder dosage is by the 4.5-8% preparation of every material total amount, binder concn about 1.5%.
A, take by weighing sodium carboxymethyl cellulose 0.09kg, add 95% ethanol of 0.15kg, stir and swelling after several hours, its is added in the distilled water solution of pigment, restir evenly promptly gets binding agent.
The preparation of b, above-mentioned pigment distilled water solution: add distilled water to required binding agent total amount among the pigment 0.00028kg (for example: in lemon yellow, light green, the amaranth etc. a kind of).
3, system wet granular:
Earlier calcium citrate, mixed powder are put slowly stir in the granulator after, add above-mentioned binding agent, restir is granulated, reuse granulator secondary granulate (screen cloth is 14 orders).
4, drying
Placing boiling drier dry the wet granular that makes, is between the 4.4-5% up to water content.
5, granulate: put granulate screen cloth 12 orders in the granulation machine in granule with dried.
6, total mixing:
A is dissolved in Mentholum 0.0015kg among the lime flavour 0.06kg, adds in the octuple amount particulate powders to mix thoroughly, gets the female powder of Mentholum essence.
B, with the female powder of dried granule, Mentholum essence, magnesium stearate (consumption 0.07kg).Place the V-Mixer mix homogeneously.
7, tabletting: every heavy 1.5g, hardness is 60-100N/mm
2Every contains calcium citrate 0.75kg (calcium 0.1575g), obeys 2-4 sheet (calcium 315-630mg) every day and is equivalent to RDA standard 39-79%.Above-mentioned prescription for adult's calcium replenishing chewing tablet.
Embodiment 2:
In the prescription citric acid consumption is increased to 0.3kg, be pregnant food in one's mouth phase women's calcium replenishing chewing tablet, all the other same adult types, technology is with embodiment 1.
Embodiment 3:
The each component consumption is respectively: calcium citrate 4.07kg; Whole milk powder 3.2kg; Mannitol 1.4kg; Glucose 0.6kg; Citric acid 0.12kg; Aspartame 0.08kg; Starch 0.28kg; Carboxymethyl cellulose 0.10kg; Pigment 0.00027kg; Milk powdered flavor 0.086kg; Magnesium stearate 0.08kg, process for preparation be with embodiment 1, and wherein whole milk powder is as one of raw material of mixed powder, and in step 8, every weight is 1.33g, hardness 45-70N/mm
2, every contains calcium citrate 0.5413g (calcium 0.1137g), obeys 3-6 sheet (calcium 340-679mg) every day, is equivalent to RDA standard 34-67.9%, and this prescription is the child form calcium replenishing chewing tablet.
Advantage of the present invention: the calcium citrate that has adopted easy dissolving, absorption in this prescription is raw material, and this contains chews Sheet does not contain sugar, free from extraneous odour, and calcium citrate and other calcium agent Performance Ratios can see the following form 1.
Table 1
| The calcium source name | Calcium carbonate | Calcium monohydrogen phosphate | Calcium activated | Calcium citrate |
| Solubility (mg/100g) | 1.0 | 2.9 | 90.1 | 95.2 |
| Acid-base value | Alkalescence | Neutral | Strong basicity | Neutralization |
| Toxicity | Little | Little | Greatly | Almost do not have |
| Effect of supplemented calcium | Generally | Difference | Better | Good |
| Gastrointestinal side effect | Bigger | Little | Greatly | Almost do not have |
| Peculiar smell | Stronger | Little | By force | Almost do not have |
| The appetite impact | Bigger | Little | Greatly | Almost do not have |
Claims (4)
1, a kind of calcium replenishing chewing tablet is characterized in that: it comprises following component: the weight percentage of each component is respectively:
Calcium citrate 45-63%
Mannitol 25-35%
Glucose 5-10%
Citric acid 1.2-3.0%
Aspartame 0.5-1.5%
Starch 1-3.2%
Binding agent 0.7-1.2%
Pigment 0.002-0.003%
Fructus Citri Limoniae essence 0.5-1.0%
Mentholum 0.01-0.02%
Magnesium stearate 0.3-1%
2, calcium replenishing chewing tablet according to claim 1 is characterized in that: described binding agent is a sodium carboxymethyl cellulose; Pigment is a kind of in lemon yellow or light green or the amaranth.
3, a kind of replenishing the calcium chewed buccal tablet, and its feature comprises following component in it, and wherein the weight percentage of each component is respectively:
Whole milk powder 28-35%
Calcium citrate 35-50%
Mannitol 10-20%
Glucose 5-10%
Citric acid 1.2-3.0%
Aspartame 0.5-1.5%
Starch 1-3.2%
Binding agent 0.7-1.2%
Pigment 0.002-0.003%
Milk powdered flavor 0.5-1.0%
Magnesium stearate 0.3-1%
4, calcium replenishing chewing tablet according to claim 3 is characterized in that: described binding agent is a sodium carboxymethyl cellulose; Pigment is a kind of in lemon yellow or light green or the amaranth.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97112058 CN1199611A (en) | 1997-05-15 | 1997-05-15 | Calcium replenishing chewing tablet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97112058 CN1199611A (en) | 1997-05-15 | 1997-05-15 | Calcium replenishing chewing tablet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1199611A true CN1199611A (en) | 1998-11-25 |
Family
ID=5172060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 97112058 Pending CN1199611A (en) | 1997-05-15 | 1997-05-15 | Calcium replenishing chewing tablet |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1199611A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101283765B (en) * | 2008-05-26 | 2010-12-29 | 北京市科威华食品工程技术有限公司 | Balsam pear slice |
| CN104083402A (en) * | 2014-06-19 | 2014-10-08 | 吉林万通药业有限公司 | Calcium chewable tablet |
| CN105106154A (en) * | 2015-09-17 | 2015-12-02 | 福建省幸福生物科技有限公司 | Sugar-free calcium tablets for middle-aged and aged people and preparation method thereof |
| CN106954778A (en) * | 2017-03-31 | 2017-07-18 | 广州市健鸣春生物科技有限公司 | A kind of suitable pregnancy period supplement Sugarless type Biocal and preparation method thereof |
-
1997
- 1997-05-15 CN CN 97112058 patent/CN1199611A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101283765B (en) * | 2008-05-26 | 2010-12-29 | 北京市科威华食品工程技术有限公司 | Balsam pear slice |
| CN104083402A (en) * | 2014-06-19 | 2014-10-08 | 吉林万通药业有限公司 | Calcium chewable tablet |
| CN105106154A (en) * | 2015-09-17 | 2015-12-02 | 福建省幸福生物科技有限公司 | Sugar-free calcium tablets for middle-aged and aged people and preparation method thereof |
| CN105106154B (en) * | 2015-09-17 | 2018-06-29 | 福建省幸福生物科技有限公司 | A kind of person in middle and old age's sugar-free calcium tablet and preparation method thereof |
| CN106954778A (en) * | 2017-03-31 | 2017-07-18 | 广州市健鸣春生物科技有限公司 | A kind of suitable pregnancy period supplement Sugarless type Biocal and preparation method thereof |
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