CN104083402A - Calcium chewable tablet - Google Patents

Calcium chewable tablet Download PDF

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Publication number
CN104083402A
CN104083402A CN201410274803.6A CN201410274803A CN104083402A CN 104083402 A CN104083402 A CN 104083402A CN 201410274803 A CN201410274803 A CN 201410274803A CN 104083402 A CN104083402 A CN 104083402A
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CN
China
Prior art keywords
parts
calcium
essence
chewable tablet
mannitol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410274803.6A
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Chinese (zh)
Inventor
潘一杭
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JILIN WANTONG PHARMACY CO Ltd
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JILIN WANTONG PHARMACY CO Ltd
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Priority to CN201410274803.6A priority Critical patent/CN104083402A/en
Publication of CN104083402A publication Critical patent/CN104083402A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a calcium chewable tablet, comprising, by weight, 20 to 80 parts of calcium lactate, 20 to 80 parts of calcium gluconate, 20 to 80 parts of calcium hydrogen phosphate, 5 to 10 parts of mannitol, 1 to 5 parts of starch, 1 to 5 parts of powdered sugar, 5 to 10 parts of citric acid, 1 to 5 parts of orange essence, 1 to 5 parts of fresh milk essence, 10 to 20 parts of lemon yellow and 1 to 5 parts of magnesium stearate. The calcium chewable tablet has improved taste, promotes maximum absorption of elemental calcium in the calcium chewable tablet by a user, delays loss of calcium in a human body and is especially applicable to populations like teenagers, adults, pregnant or lactating women and postmenopausal women.

Description

A kind of Biocal
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of Biocal.
Background technology
Calcium is one of element the most general in human body, is called as " armored concrete in life ", and in human body, the content of calcium accounts for the 1.5--2% of TBW, and wherein skeleton and tooth account for 99%.Body fluid and soft tissue account for 1%.For body metabolism, cell function, nervous system running, protein hormones are synthetic etc., play vital effect.In the person, calcium deficiency there will be the diseases such as osteoporosis, tetany disease, dysosteogenesis, rickets, and especially gestation and women breast-feeding their children, menopausal women calcium deficiency, can cause larger infringement to health.
Therefore, prior art needs further improve and develop.
Summary of the invention
In view of above-mentioned the deficiencies in the prior art, the object of the present invention is to provide a kind of Biocal, so that human body can fully absorb calcium, the loss of calcium in delaying human body.
Technical scheme of the present invention is as follows:
A Biocal, it is composed of the following components according to weight portion:
The calcium lactate of 20 parts-80 parts, the calcium gluconate of 20 parts-80 parts, the calcium hydrogen phosphate of 20 parts-80 parts, the mannitol of 5 parts-10 parts, the starch of 1 part-5 parts, the Icing Sugar of 1 part-5 parts, the citric acid of 5 parts-10 parts, the flavoring orange essence of 1 part-5 parts, the fresh milk essence of 1 part-5 parts, the lemon yellow of 10 parts-20 parts and the magnesium stearate of 1 part-5 parts.
Described Biocal, wherein, it is composed of the following components according to weight portion: the calcium lactate of 50 parts, the calcium gluconate of 50 parts, the calcium hydrogen phosphate of 50 parts, the mannitol of 10 parts, the starch of 5 parts, the Icing Sugar of 1 part, the citric acid of 5 parts, the flavoring orange essence of 1 part, the fresh milk essence of 1 part, the lemon yellow of 20 parts and the magnesium stearate of 1 part.
The described calcium tablet of chewing, wherein, it is composed of the following components according to weight portion: the calcium lactate of 80 parts, the calcium gluconate of 80 parts, the calcium hydrogen phosphate of 80 parts, the mannitol of 6 parts, the starch of 3 parts, the Icing Sugar of 2 parts, the citric acid of 10 parts, the flavoring orange essence of 4 parts, the fresh milk essence of 2 parts, the lemon yellow of 15 parts and the magnesium stearate of 3 parts.
A kind of Biocal provided by the invention, adopt the technical scheme of 5 calcium lactate, calcium gluconate, calcium hydrogen phosphate, mannitol, starch, Icing Sugar, citric acid, flavoring orange essence, fresh milk essence, lemon yellow, magnesium stearate, improved the mouthfeel of chewable tablet, and coordinate the adjuvants such as mannitol, citric acid, flavoring orange essence, fresh milk essence, lemon yellow, promote that user farthest absorbs the calcium constituent in Biocal, the loss of calcium in delaying human body, is especially applicable to teenager, is grown up, is pregnent and the crowd such as women breast-feeding their children, menopausal women.
The specific embodiment
The invention provides a kind of Biocal, for making object of the present invention, technical scheme and effect clearer, clear and definite, below the present invention is described in more detail.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
The invention provides a kind of Biocal, it is composed of the following components according to weight portion:
The calcium lactate of 20 parts-80 parts, the calcium gluconate of 20 parts-80 parts, the calcium hydrogen phosphate of 20 parts-80 parts, the mannitol of 5 parts-10 parts, the starch of 1 part-5 parts, the Icing Sugar of 1 part-5 parts, the citric acid of 5 parts-10 parts, the flavoring orange essence of 1 part-5 parts, the fresh milk essence of 1 part-5 parts, the lemon yellow of 10 parts-20 parts and the magnesium stearate of 1 part-5 parts.
In another preferred embodiment of the present invention, it is composed of the following components according to weight portion: the calcium lactate of 50 parts, the calcium gluconate of 50 parts, the calcium hydrogen phosphate of 50 parts, the mannitol of 10 parts, the starch of 5 parts, the Icing Sugar of 1 part, the citric acid of 5 parts, the flavoring orange essence of 1 part, the fresh milk essence of 1 part, the lemon yellow of 20 parts and the magnesium stearate of 1 part.
In another preferred embodiment, it is composed of the following components according to weight portion: the calcium lactate of 80 parts, the calcium gluconate of 80 parts, the calcium hydrogen phosphate of 80 parts, the mannitol of 6 parts, the starch of 3 parts, the Icing Sugar of 2 parts, the citric acid of 10 parts, the flavoring orange essence of 4 parts, the fresh milk essence of 2 parts, the lemon yellow of 15 parts and the magnesium stearate of 3 parts.
In order further to describe the present invention, below enumerate more detailed embodiment and describe.
Adopt the calcium lactate of 6000 milligrams, the calcium gluconate of 6000 milligrams, the calcium hydrogen phosphate of 6000 milligrams, the mannitol of 1200 milligrams, the starch of 600 milligrams, the Icing Sugar of 120 milligrams, the citric acid of 600 milligrams, the flavoring orange essence of 120 milligrams, the fresh milk essence of 120 milligrams, the lemon yellow of 2400 milligrams and the magnesium stearate of 120 milligrams, make 120 Biocals.Choose 140 people as a control group, comprising 50 teenagers of 15 years old-18 years old, 30 person between twenty and fifty of 25 years old-35 years old, 20 anemia of pregnant woman of 28 years old-31 years old, 40 old men of 60 years old-70 years old; Choose 130 people as experimental group, 40 teenagers of 12 years old-16 years old wherein, 25 person between twenty and fifty of 30 years old-40 years old, 30 anemia of pregnant woman of 28 years old-31 years old, 60 old men of 65 years old-80 years old.Matched group normal diet, experimental group according to one time 2~4, the dosage of 3 times on the one is taken.Afterwards the skeleton of matched group and experimental group is measured, experimental group crowd's skeleton toughness, intensity and calcium current vector are all significantly better than matched group.
This Biocal is ground to form after powdery, inject pure water and soak, carry out conductive test, bulb brightens, and illustrates that Biocal dissolubility is good, can alleviate the burden of stomach, is convenient to absorption of human body.
40 18g-22g mices are divided into 2 groups at random, every group 20, feeding for one group adds the normal feedstuff of Biocal powder, another group to feed normal diet, adaptability was fed after 3 days, gavage 4 weeks, one group gavages solution containing Biocal powder, one group and gavages regular solution, and testing index has final body weight, calcium absorptivity, calcium content of bone, serum calcium levels, Femur index, the femur weight of mice.Result shows, eats chewable tablet powder group mice each side index all higher than common group of mice.
Should be understood that, application of the present invention is not limited to above-mentioned giving an example, and for those of ordinary skills, can be improved according to the above description or convert, and all these improvement and conversion all should belong to the protection domain of claims of the present invention.

Claims (3)

1. a Biocal, it is composed of the following components according to weight portion:
The calcium lactate of 20 parts-80 parts, the calcium gluconate of 20 parts-80 parts, the calcium hydrogen phosphate of 20 parts-80 parts, the mannitol of 5 parts-10 parts, the starch of 1 part-5 parts, the Icing Sugar of 1 part-5 parts, the citric acid of 5 parts-10 parts, the flavoring orange essence of 1 part-5 parts, the fresh milk essence of 1 part-5 parts, the lemon yellow of 10 parts-20 parts and the magnesium stearate of 1 part-5 parts.
2. Biocal according to claim 1, it is characterized in that, it is composed of the following components according to weight portion: the calcium lactate of 50 parts, the calcium gluconate of 50 parts, the calcium hydrogen phosphate of 50 parts, the mannitol of 10 parts, the starch of 5 parts, the Icing Sugar of 1 part, the citric acid of 5 parts, the flavoring orange essence of 1 part, the fresh milk essence of 1 part, the lemon yellow of 20 parts and the magnesium stearate of 1 part.
3. the calcium tablet of chewing according to claim 1, it is characterized in that, it is composed of the following components according to weight portion: the calcium lactate of 80 parts, the calcium gluconate of 80 parts, the calcium hydrogen phosphate of 80 parts, the mannitol of 6 parts, the starch of 3 parts, the Icing Sugar of 2 parts, the citric acid of 10 parts, the flavoring orange essence of 4 parts, the fresh milk essence of 2 parts, the lemon yellow of 15 parts and the magnesium stearate of 3 parts.
CN201410274803.6A 2014-06-19 2014-06-19 Calcium chewable tablet Pending CN104083402A (en)

Priority Applications (1)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104523612A (en) * 2014-12-05 2015-04-22 海南卫康制药(潜山)有限公司 Calcium lactate composition chewable tablet and preparation method thereof
CN104906129A (en) * 2015-06-15 2015-09-16 吉林万通药业有限公司 Calcium carbonate tablet and preparation method thereof
CN106954778A (en) * 2017-03-31 2017-07-18 广州市健鸣春生物科技有限公司 A kind of suitable pregnancy period supplement Sugarless type Biocal and preparation method thereof
CN109221421A (en) * 2018-09-27 2019-01-18 芜湖市好亦快食品有限公司三山分公司 It is a kind of to add calcium composite chewable tablet and preparation method thereof containing colostrum

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1199611A (en) * 1997-05-15 1998-11-25 北京路德有限责任公司 Calcium replenishing chewing tablet
CN101404899A (en) * 2006-01-11 2009-04-08 米申制药公司 Calcium-enriched food product
CN102133390A (en) * 2011-03-11 2011-07-27 林峰 Calcium tablets and production process
CN103202483A (en) * 2012-01-11 2013-07-17 浙江康恩贝健康产品有限公司 Nutritional composition for calcium supplement

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1199611A (en) * 1997-05-15 1998-11-25 北京路德有限责任公司 Calcium replenishing chewing tablet
CN101404899A (en) * 2006-01-11 2009-04-08 米申制药公司 Calcium-enriched food product
CN102133390A (en) * 2011-03-11 2011-07-27 林峰 Calcium tablets and production process
CN103202483A (en) * 2012-01-11 2013-07-17 浙江康恩贝健康产品有限公司 Nutritional composition for calcium supplement

Non-Patent Citations (3)

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Title
程元元: "补钙对人体健康的重要性及临床常用制剂", 《海峡药学》, vol. 19, no. 8, 31 December 2007 (2007-12-31) *
邵丽君: "钙制剂的应用和选择", 《当代医学》, vol. 15, no. 21, 31 July 2009 (2009-07-31) *
高宪枫 等: "论钙的营养与强化", 《食品与发酵工业》, no. 04, 31 December 1999 (1999-12-31) *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104523612A (en) * 2014-12-05 2015-04-22 海南卫康制药(潜山)有限公司 Calcium lactate composition chewable tablet and preparation method thereof
CN104906129A (en) * 2015-06-15 2015-09-16 吉林万通药业有限公司 Calcium carbonate tablet and preparation method thereof
CN106954778A (en) * 2017-03-31 2017-07-18 广州市健鸣春生物科技有限公司 A kind of suitable pregnancy period supplement Sugarless type Biocal and preparation method thereof
CN109221421A (en) * 2018-09-27 2019-01-18 芜湖市好亦快食品有限公司三山分公司 It is a kind of to add calcium composite chewable tablet and preparation method thereof containing colostrum

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Application publication date: 20141008