CN102133390A - Calcium tablets and production process - Google Patents
Calcium tablets and production process Download PDFInfo
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- CN102133390A CN102133390A CN2011100612945A CN201110061294A CN102133390A CN 102133390 A CN102133390 A CN 102133390A CN 2011100612945 A CN2011100612945 A CN 2011100612945A CN 201110061294 A CN201110061294 A CN 201110061294A CN 102133390 A CN102133390 A CN 102133390A
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Abstract
The invention discloses calcium tablets and a production process. 100 calcium tablets can be prepared from the following raw materials: 745 grams of calcium carbonate, 200 grams of calcium citrate, 100 grams of casein phosphopeptide, 15 grams of citric acid, 2 grams of orange essence, 80 grams of mannitol, 3 grams of aspartame, 0.1 gram of lemon yellow, 49.9 grams of microcrystalline cellulose and 5 grams of magnesium stearate. The calcium tablets are convenient to eat, do not have side effect and can be easily absorbed by human bodies.
Description
Technical field
The present invention relates to field of health care products, refer more particularly to a kind of calcium tablet and production technology thereof.
Background technology
Human body calcium deficiency and calcium are migrated and can be caused unsound many reasons, as osteoporosis, hyperosteogeny, hyperosteogeny, prolapse of lumbar intervertebral disc, fatiguability, the whole body is weak, sore waist and aching in the waist and the back, ductus arteriosus wall medicated porridge sample lipid calmness, thereby cause hypertension, arteriosclerosis, coronary heart disease, cause cerebral arterial insufficiency, make the cerebral tissue hypoxic-ischemic, thereby impel the brain function decline, hypomnesis, ability of thinking goes down, calcium deficiency, calcium is migrated, also have a strong impact on nervous system, it also is the pathogenic factor of senile dementia, also can cause strong intestinal, unhealthy problem such as constipation occurs.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point of the prior art and provide a kind of and replenish the calcium, stay calcium, instant edible, the simple calcium tablet of production technology and production technology thereof.
The present invention realizes in the following way:
A kind of calcium tablet and production technology thereof is characterized in that: this calcium tablet is to be made by following raw material:
Calcium carbonate 745g, calcium citrate 200g, phosphopeptide caseinate 100g, citric acid 15g, orange essence 2g, mannitol 80g, aspartame 3g, lemon yellow 0.1g, microcrystalline Cellulose 49.9g, magnesium stearate 5g, above dosage can be made 1000 calcium tablet.
The production technology of this calcium tablet is:
(1), sieve, weighing: calcium carbonate, calcium citrate, mannitol, aspartame, phosphopeptide caseinate, microcrystalline Cellulose, orange essence, magnesium stearate are crossed 80 mesh sieves respectively, standby; Citric acid is pulverized the back cross 80 mesh sieves, standby;
Calcium carbonate, calcium citrate, phosphopeptide caseinate, citric acid, orange essence, mannitol, aspartame, lemon yellow, microcrystalline Cellulose, magnesium stearate are taken by weighing by formula ratio, standby;
Lemon yellow adds the dissolving of 10ml purified water, and is standby;
(2), mix: get aspartame, orange essence, citric acid mixing, get mixed powder A; Microcrystalline Cellulose, mannitol, phosphopeptide caseinate and mixed powder A, it is even to be fully mixed to color and luster, mixed powder B; Calcium carbonate, calcium citrate and mixed powder B put mix 20min in the mixer, mixed powder; Lemon yellow solution is evenly sprayed in the mixed powder, adopt cold drying, temperature is controlled at 50 ± 5 ℃, crosses 80 mesh sieves, and it is even to be fully mixed to color and luster, total mixed powder;
(3), granulate: total mixed powder is inserted in the dry granulation machine, and dry method system granule is crossed 16 mesh sieves, must granule, with mixer mixing 15min, it is even to be fully mixed to color and luster, obtains hybrid particles with granule and magnesium stearate;
(4), tabletting, packing, product inspection, warehouse-in: hybrid particles is put tablet machine, and adjustment sheet weighs the 1.2g/ sheet, and pressure carries out tabletting, gets tablet, bottling, 60 every bottle; Product inspection, warehousing after passing.
Production environment is to carry out under 300,000 grades of clean area conditions in preparation process.
The invention has the advantages that:
1, prescription innovation, rationally.
2, production technology is simple.
3, easily store, carry, taking convenience.
Description of drawings
Fig. 1 process diagram of the present invention.
The specific embodiment
The specific embodiment of the invention is described in detail in detail:
As shown in Figure 1: a kind of calcium tablet and production technology thereof is characterized in that: this calcium tablet is to be made by following raw material:
Calcium carbonate 745g, calcium citrate 200g, phosphopeptide caseinate 100g, citric acid 15g, orange essence 2g, mannitol 80g, aspartame 3g, lemon yellow 0.1g, microcrystalline Cellulose 49.9g, magnesium stearate 5g, above dosage can be made 1000 calcium tablet.
The production technology of this calcium tablet is:
(1), sieve, weighing: calcium carbonate, calcium citrate, mannitol, aspartame, phosphopeptide caseinate, microcrystalline Cellulose, orange essence, magnesium stearate are crossed 80 mesh sieves respectively, standby; Citric acid is pulverized the back cross 80 mesh sieves, standby;
Calcium carbonate, calcium citrate, phosphopeptide caseinate, citric acid, orange essence, mannitol, aspartame, lemon yellow, microcrystalline Cellulose, magnesium stearate are taken by weighing by formula ratio, standby;
Lemon yellow adds the dissolving of 10ml purified water, and is standby;
(2), mix: get aspartame, orange essence, citric acid mixing, get mixed powder A; Microcrystalline Cellulose, mannitol, phosphopeptide caseinate and mixed powder A, it is even to be fully mixed to color and luster, mixed powder B; Calcium carbonate, calcium citrate and mixed powder B put mix 20min in the mixer, mixed powder; Lemon yellow solution is evenly sprayed in the mixed powder, adopt cold drying, temperature is controlled at 50 ± 5 ℃, crosses 80 mesh sieves, and it is even to be fully mixed to color and luster, total mixed powder;
(3), granulate: total mixed powder is inserted in the dry granulation machine, and dry method system granule is crossed 16 mesh sieves, must granule, with mixer mixing 15min, it is even to be fully mixed to color and luster, obtains hybrid particles with granule and magnesium stearate;
(4), tabletting, packing, product inspection, warehouse-in: hybrid particles is put tablet machine, and adjustment sheet weighs the 1.2g/ sheet, and pressure carries out tabletting, gets tablet, bottling, 60 every bottle; Product inspection, warehousing after passing.
Production environment is to carry out under 300,000 grades of clean area conditions in preparation process.
Embodiment:
(1), calcium carbonate, calcium citrate, mannitol, aspartame, phosphopeptide caseinate, microcrystalline Cellulose, orange essence, magnesium stearate 80 mesh sieves respectively excessively, standby; Citric acid is pulverized the back cross 80 mesh sieves, standby;
Calcium carbonate 745g, calcium citrate 200g, phosphopeptide caseinate 100g, citric acid 15g, orange essence 2g, mannitol 80g, aspartame 3g, lemon yellow 0.1g, microcrystalline Cellulose 49.9g, magnesium stearate 5g are taken by weighing according to quantity, standby;
Lemon yellow 0.1g adds the dissolving of 10ml purified water, and is standby;
(2), get aspartame 3g, orange essence 2g, citric acid 15g and mix, mixed powder A; Getting microcrystalline Cellulose 49.9g, mannitol 80g, phosphopeptide caseinate 100g and mixed powder A, to be fully mixed to color and luster even, mixed powder B; Calcium carbonate 745g, calcium citrate 200g and mixed powder B put mix 20min in the mixer, mixed powder; Lemon yellow solution is evenly sprayed in the mixed powder, adopt cold drying, temperature is controlled at 50 ± 5 ℃, crosses 80 mesh sieves, and it is even to be fully mixed to color and luster, total mixed powder;
(3), total mixed powder is inserted in the dry granulation machine, dry method system granule is crossed 16 mesh sieves, granule, with mixer mixing 15min, it is even to be fully mixed to color and luster, obtains hybrid particles with granule and magnesium stearate;
(4), hybrid particles is put tablet machine, the heavy 1.2g/ sheet of adjustment sheet, pressure carries out tabletting, tablet, bottling, 60 every bottle; Product inspection, warehousing after passing.
The present invention selects solid preparation for use, advantages such as solid preparation has stable in properties, stores easily, carries, taking convenience, and instructions of taking of the present invention adopts chews food, avoid the child because of being difficult for swallowing generation danger, be convenient to promote the absorption of calcium, quicken disintegrate, help bringing into play effect.
Claims (3)
1. calcium tablet and production technology thereof, it is characterized in that: this calcium tablet is to be made by following raw material: calcium carbonate 745g, calcium citrate 200g, phosphopeptide caseinate 100g, citric acid 15g, orange essence 2g, mannitol 80g, aspartame 3g, lemon yellow 0.1g, microcrystalline Cellulose 49.9g, magnesium stearate 5g, above dosage can be made 1000 calcium tablet.
2. a kind of calcium tablet according to claim 1 and production technology thereof is characterized in that: the production technology of this calcium tablet is:
(1), sieve, weighing: calcium carbonate, calcium citrate, mannitol, aspartame, phosphopeptide caseinate, microcrystalline Cellulose, orange essence, magnesium stearate are crossed 80 mesh sieves respectively, standby; Citric acid is pulverized the back cross 80 mesh sieves, standby;
Calcium carbonate, calcium citrate, phosphopeptide caseinate, citric acid, orange essence, mannitol, aspartame, lemon yellow, microcrystalline Cellulose, magnesium stearate are taken by weighing according to quantity, standby;
Lemon yellow adds the dissolving of 10ml purified water, and is standby;
(2), mix: get aspartame, orange essence, citric acid mixing, get mixed powder (A); Microcrystalline Cellulose, mannitol, phosphopeptide caseinate and mixed powder (A), it is even to be fully mixed to color and luster, mixed powder (B); Calcium carbonate, calcium citrate and mixed powder (B) put mix 20min in the mixer, mixed powder; Lemon yellow solution is evenly sprayed in the mixed powder, adopt cold drying, temperature is controlled at 50 ± 5 ℃, crosses 80 mesh sieves, and it is even to be fully mixed to color and luster, total mixed powder;
(3), granulate: total mixed powder is inserted in the dry granulation machine, and dry method system granule is crossed 16 mesh sieves, must granule, with mixer mixing 15min, it is even to be fully mixed to color and luster, obtains hybrid particles with granule and magnesium stearate;
(4), tabletting, packing, product inspection, warehouse-in: hybrid particles is put tablet machine, and adjustment sheet weighs the 1.2g/ sheet, and pressure carries out tabletting, gets tablet, bottling, 60 every bottle; Product inspection, warehousing after passing.
3. a kind of calcium tablet according to claim 2 and production technology thereof is characterized in that: production environment is to carry out under 300,000 grades of clean area conditions in preparation process.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100612945A CN102133390A (en) | 2011-03-11 | 2011-03-11 | Calcium tablets and production process |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100612945A CN102133390A (en) | 2011-03-11 | 2011-03-11 | Calcium tablets and production process |
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| CN102133390A true CN102133390A (en) | 2011-07-27 |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103417520A (en) * | 2013-08-21 | 2013-12-04 | 成都润华堂制药有限公司 | Combined calcium preparation |
| CN103961688A (en) * | 2014-04-30 | 2014-08-06 | 湖北神地农业科贸有限公司 | Eggshell source compound calcium citrate chewable tablet and preparation method thereof |
| CN104083402A (en) * | 2014-06-19 | 2014-10-08 | 吉林万通药业有限公司 | Calcium chewable tablet |
| CN104217937A (en) * | 2014-08-26 | 2014-12-17 | 合肥京东方光电科技有限公司 | Attaching device of anisotropic conductive films and adjustment method of cutter |
| CN106954778A (en) * | 2017-03-31 | 2017-07-18 | 广州市健鸣春生物科技有限公司 | A kind of suitable pregnancy period supplement Sugarless type Biocal and preparation method thereof |
| CN108719981A (en) * | 2018-05-18 | 2018-11-02 | 吕莉 | A kind of preparation method of enzyme microb calcium effervescence tablet |
| CN109846901A (en) * | 2019-04-03 | 2019-06-07 | 江西安顺堂生物科技有限公司 | It is a kind of to promote bone growth, anti-caries, the preparation and preparation process for supplementing calcium |
| CN110122880A (en) * | 2019-06-19 | 2019-08-16 | 安徽康博特保健食品有限公司 | A kind of calcium and magnesium piece health food and preparation method thereof |
| CN110354138A (en) * | 2019-07-18 | 2019-10-22 | 宿迁市现代生物科技股份有限公司 | A kind of formula of the granular calcium carbonate of the directly compressible of low abrasion |
| CN116671638A (en) * | 2023-06-15 | 2023-09-01 | 江西维莱营健高科有限公司 | Casein calcium tablet and preparation method thereof |
-
2011
- 2011-03-11 CN CN2011100612945A patent/CN102133390A/en active Pending
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103417520A (en) * | 2013-08-21 | 2013-12-04 | 成都润华堂制药有限公司 | Combined calcium preparation |
| CN103961688A (en) * | 2014-04-30 | 2014-08-06 | 湖北神地农业科贸有限公司 | Eggshell source compound calcium citrate chewable tablet and preparation method thereof |
| CN103961688B (en) * | 2014-04-30 | 2016-05-25 | 湖北神地农业科贸有限公司 | A kind of eggshell source compound lemon acid Biocal and preparation method thereof |
| CN104083402A (en) * | 2014-06-19 | 2014-10-08 | 吉林万通药业有限公司 | Calcium chewable tablet |
| CN104217937A (en) * | 2014-08-26 | 2014-12-17 | 合肥京东方光电科技有限公司 | Attaching device of anisotropic conductive films and adjustment method of cutter |
| CN106954778A (en) * | 2017-03-31 | 2017-07-18 | 广州市健鸣春生物科技有限公司 | A kind of suitable pregnancy period supplement Sugarless type Biocal and preparation method thereof |
| CN108719981A (en) * | 2018-05-18 | 2018-11-02 | 吕莉 | A kind of preparation method of enzyme microb calcium effervescence tablet |
| CN109846901A (en) * | 2019-04-03 | 2019-06-07 | 江西安顺堂生物科技有限公司 | It is a kind of to promote bone growth, anti-caries, the preparation and preparation process for supplementing calcium |
| CN110122880A (en) * | 2019-06-19 | 2019-08-16 | 安徽康博特保健食品有限公司 | A kind of calcium and magnesium piece health food and preparation method thereof |
| CN110354138A (en) * | 2019-07-18 | 2019-10-22 | 宿迁市现代生物科技股份有限公司 | A kind of formula of the granular calcium carbonate of the directly compressible of low abrasion |
| CN116671638A (en) * | 2023-06-15 | 2023-09-01 | 江西维莱营健高科有限公司 | Casein calcium tablet and preparation method thereof |
| CN116671638B (en) * | 2023-06-15 | 2024-03-22 | 江西维莱营健高科有限公司 | Casein calcium tablet and preparation method thereof |
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Application publication date: 20110727 |
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