CN119497719A - Serpin肽衍生物及其使用方法 - Google Patents

Serpin肽衍生物及其使用方法 Download PDF

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Publication number
CN119497719A
CN119497719A CN202380042370.9A CN202380042370A CN119497719A CN 119497719 A CN119497719 A CN 119497719A CN 202380042370 A CN202380042370 A CN 202380042370A CN 119497719 A CN119497719 A CN 119497719A
Authority
CN
China
Prior art keywords
amino acid
peptide derivative
serpin
serpin peptide
core sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202380042370.9A
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English (en)
Chinese (zh)
Inventor
C·格伯
西里尔·吉内斯特
达纳·奥斯汀
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SERPIN PHARMA LLC
Original Assignee
SERPIN PHARMA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SERPIN PHARMA LLC filed Critical SERPIN PHARMA LLC
Publication of CN119497719A publication Critical patent/CN119497719A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202380042370.9A 2022-04-29 2023-04-27 Serpin肽衍生物及其使用方法 Pending CN119497719A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263363840P 2022-04-29 2022-04-29
US63/363,840 2022-04-29
PCT/US2023/066321 WO2023212661A1 (en) 2022-04-29 2023-04-27 Serpin peptide derivatives and methods of using the same

Publications (1)

Publication Number Publication Date
CN119497719A true CN119497719A (zh) 2025-02-21

Family

ID=88519894

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380042370.9A Pending CN119497719A (zh) 2022-04-29 2023-04-27 Serpin肽衍生物及其使用方法

Country Status (9)

Country Link
US (1) US20250353898A1 (https=)
EP (1) EP4514838A1 (https=)
JP (1) JP2025515349A (https=)
CN (1) CN119497719A (https=)
AU (1) AU2023260921A1 (https=)
CA (1) CA3256966A1 (https=)
IL (1) IL316583A (https=)
MX (1) MX2024013323A (https=)
WO (1) WO2023212661A1 (https=)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439829A (en) * 1991-01-30 1995-08-08 Eli Lilly And Company Immobilization of biologically active molecules by changing the Oxidation state of a chelated transition metal ion
GB0916578D0 (en) * 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
CN102731626B (zh) * 2011-04-13 2014-10-01 中国人民解放军军事医学科学院毒物药物研究所 环肽及其医药用途
CA3077804C (en) * 2012-01-09 2023-07-25 Serpin Pharma, Llc Peptides and methods of using same
WO2013172954A1 (en) * 2012-05-17 2013-11-21 Ra Pharmaceuticals, Inc Peptide and peptidomimetic inhibitors
WO2016154041A1 (en) * 2015-03-20 2016-09-29 University Of Florida Research Foundation Incorporated Serpin reactive center loop peptides and methods of use
WO2021219896A1 (en) * 2020-05-01 2021-11-04 Atlas Biotechnology S.A. Treatment and/or prevention of a disease or a syndrome related to a virus infection
EP4003391A4 (en) * 2020-07-06 2023-02-22 Serpin Pharma, LLC PEPTIDES AND METHODS OF USE THEREOF

Also Published As

Publication number Publication date
EP4514838A1 (en) 2025-03-05
WO2023212661A1 (en) 2023-11-02
US20250353898A1 (en) 2025-11-20
AU2023260921A1 (en) 2024-11-07
CA3256966A1 (en) 2023-11-02
MX2024013323A (es) 2024-12-06
JP2025515349A (ja) 2025-05-14
IL316583A (en) 2024-12-01

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