JP2025515349A - Ｓｅｒｐｉｎペプチド誘導体およびその使用方法 - Google Patents

Ｓｅｒｐｉｎペプチド誘導体およびその使用方法 Download PDF

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Publication number
JP2025515349A
JP2025515349A JP2024563519A JP2024563519A JP2025515349A JP 2025515349 A JP2025515349 A JP 2025515349A JP 2024563519 A JP2024563519 A JP 2024563519A JP 2024563519 A JP2024563519 A JP 2024563519A JP 2025515349 A JP2025515349 A JP 2025515349A
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amino acid
serpin
peptide derivative
serpin peptide
acid residues
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JP2024563519A
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Japanese (ja)
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JP2025515349A5 (https=
Inventor
コハヴァ ゲルバー
シリル ジネステ
デイナ オースティン
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セルピン ファーマ リミテッド ライアビリティ カンパニー
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Publication of JP2025515349A publication Critical patent/JP2025515349A/ja
Publication of JP2025515349A5 publication Critical patent/JP2025515349A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2024563519A 2022-04-29 2023-04-27 Ｓｅｒｐｉｎペプチド誘導体およびその使用方法 Pending JP2025515349A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263363840P 2022-04-29 2022-04-29
US63/363,840 2022-04-29
PCT/US2023/066321 WO2023212661A1 (en) 2022-04-29 2023-04-27 Serpin peptide derivatives and methods of using the same

Publications (2)

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JP2025515349A true JP2025515349A (ja) 2025-05-14
JP2025515349A5 JP2025515349A5 (https=) 2025-06-02

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JP2024563519A Pending JP2025515349A (ja) 2022-04-29 2023-04-27 Ｓｅｒｐｉｎペプチド誘導体およびその使用方法

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US (1) US20250353898A1 (https=)
EP (1) EP4514838A1 (https=)
JP (1) JP2025515349A (https=)
CN (1) CN119497719A (https=)
AU (1) AU2023260921A1 (https=)
CA (1) CA3256966A1 (https=)
IL (1) IL316583A (https=)
MX (1) MX2024013323A (https=)
WO (1) WO2023212661A1 (https=)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012139519A1 (zh) * 2011-04-13 2012-10-18 中国人民解放军军事医学科学院毒物药物研究所 环肽及其医药用途
JP2013505286A (ja) * 2009-09-22 2013-02-14 エクセルミューネ・アクチエボラーグ ポリペプチド及びその使用
JP2015504073A (ja) * 2012-01-09 2015-02-05 セルピン ファーマ リミテッド ライアビリティ カンパニー ペプチドおよびその使用法
WO2016154041A1 (en) * 2015-03-20 2016-09-29 University Of Florida Research Foundation Incorporated Serpin reactive center loop peptides and methods of use
WO2021219896A1 (en) * 2020-05-01 2021-11-04 Atlas Biotechnology S.A. Treatment and/or prevention of a disease or a syndrome related to a virus infection
WO2022010939A2 (en) * 2020-07-06 2022-01-13 Serpin Pharma, Llc Peptides and methods of using the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439829A (en) * 1991-01-30 1995-08-08 Eli Lilly And Company Immobilization of biologically active molecules by changing the Oxidation state of a chelated transition metal ion
WO2013172954A1 (en) * 2012-05-17 2013-11-21 Ra Pharmaceuticals, Inc Peptide and peptidomimetic inhibitors

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013505286A (ja) * 2009-09-22 2013-02-14 エクセルミューネ・アクチエボラーグ ポリペプチド及びその使用
WO2012139519A1 (zh) * 2011-04-13 2012-10-18 中国人民解放军军事医学科学院毒物药物研究所 环肽及其医药用途
JP2015504073A (ja) * 2012-01-09 2015-02-05 セルピン ファーマ リミテッド ライアビリティ カンパニー ペプチドおよびその使用法
WO2016154041A1 (en) * 2015-03-20 2016-09-29 University Of Florida Research Foundation Incorporated Serpin reactive center loop peptides and methods of use
US20180319868A1 (en) * 2015-03-20 2018-11-08 University Of Florida Research Foundation, Incorporated Serpin reactive center loop peptides and methods of use
WO2021219896A1 (en) * 2020-05-01 2021-11-04 Atlas Biotechnology S.A. Treatment and/or prevention of a disease or a syndrome related to a virus infection
WO2022010939A2 (en) * 2020-07-06 2022-01-13 Serpin Pharma, Llc Peptides and methods of using the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WOHLFORD GF, ET AL.: "A phase 1 clinical trial of SP16, a first-in-class anti-inflammatory LRP1 agonist, in healthy volunt", PLOS ONE, vol. Vol. 16 (5), JPN6026014615, 6 May 2021 (2021-05-06), pages 0247357, ISSN: 0005837948 *

Also Published As

Publication number Publication date
EP4514838A1 (en) 2025-03-05
WO2023212661A1 (en) 2023-11-02
CN119497719A (zh) 2025-02-21
US20250353898A1 (en) 2025-11-20
AU2023260921A1 (en) 2024-11-07
CA3256966A1 (en) 2023-11-02
MX2024013323A (es) 2024-12-06
IL316583A (en) 2024-12-01

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