CN119213007A - 鹅脱氧胆酸钠的形式和组合物 - Google Patents

鹅脱氧胆酸钠的形式和组合物 Download PDF

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Publication number
CN119213007A
CN119213007A CN202380040160.6A CN202380040160A CN119213007A CN 119213007 A CN119213007 A CN 119213007A CN 202380040160 A CN202380040160 A CN 202380040160A CN 119213007 A CN119213007 A CN 119213007A
Authority
CN
China
Prior art keywords
solid form
peaks
xrpd pattern
degrees
theta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202380040160.6A
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English (en)
Chinese (zh)
Inventor
C·纳波利塔诺
M·马里诺
C·弗拉迪斯科维奇
A·雷斯泰利
C-M·曼塔
A-A·帕特拉斯库
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sintis Biotechnology Co ltd
Original Assignee
Sintis Biotechnology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT102022000006161A external-priority patent/IT202200006161A1/it
Priority claimed from IT102022000019725A external-priority patent/IT202200019725A1/it
Application filed by Sintis Biotechnology Co ltd filed Critical Sintis Biotechnology Co ltd
Publication of CN119213007A publication Critical patent/CN119213007A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202380040160.6A 2022-03-29 2023-03-28 鹅脱氧胆酸钠的形式和组合物 Pending CN119213007A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT102022000006161A IT202200006161A1 (it) 2022-03-29 2022-03-29 Forms and compositions of sodium chenodeoxycholate
IT102022000006161 2022-03-29
IT102022000019725 2022-09-26
IT102022000019725A IT202200019725A1 (it) 2022-09-26 2022-09-26 Forme e composizioni del chenodeossicolato di sodio
PCT/US2023/016486 WO2023192221A1 (en) 2022-03-29 2023-03-28 Forms and compositions of sodium chenodeoxycholate

Publications (1)

Publication Number Publication Date
CN119213007A true CN119213007A (zh) 2024-12-27

Family

ID=88203205

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380040160.6A Pending CN119213007A (zh) 2022-03-29 2023-03-28 鹅脱氧胆酸钠的形式和组合物

Country Status (5)

Country Link
US (1) US20250206773A1 (https=)
EP (1) EP4499660A1 (https=)
JP (1) JP2025511126A (https=)
CN (1) CN119213007A (https=)
WO (1) WO2023192221A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7814075B1 (ja) * 2025-09-18 2026-02-16 株式会社フジモト・コーポレーション 錠剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130102580A1 (en) * 2011-09-22 2013-04-25 Kythera Biopharmaceuticals, Inc. Compositions and methods related to deoxycholic acid and its polymorphs
TW201704251A (zh) * 2015-04-29 2017-02-01 正大天晴藥業集團股份有限公司 鵝去氧膽酸衍生物
CN109762043B (zh) * 2019-03-06 2020-07-24 华南理工大学 鹅去氧胆酸及其制备方法

Also Published As

Publication number Publication date
EP4499660A1 (en) 2025-02-05
US20250206773A1 (en) 2025-06-26
WO2023192221A1 (en) 2023-10-05
JP2025511126A (ja) 2025-04-15

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