CN119033822A - 用于抑制癫痫发作的组合物和方法 - Google Patents

用于抑制癫痫发作的组合物和方法 Download PDF

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Publication number
CN119033822A
CN119033822A CN202411196564.7A CN202411196564A CN119033822A CN 119033822 A CN119033822 A CN 119033822A CN 202411196564 A CN202411196564 A CN 202411196564A CN 119033822 A CN119033822 A CN 119033822A
Authority
CN
China
Prior art keywords
subject
mice
bacteria
seizure
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202411196564.7A
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English (en)
Chinese (zh)
Inventor
E·萧
J·矢野
H·王
C·奥尔森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
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University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of CN119033822A publication Critical patent/CN119033822A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30Dietetic or nutritional methods, e.g. for losing weight
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0216Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • A61K2035/115Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Dairy Products (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CN202411196564.7A 2016-12-20 2017-12-20 用于抑制癫痫发作的组合物和方法 Pending CN119033822A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662436711P 2016-12-20 2016-12-20
US62/436,711 2016-12-20
US201762447992P 2017-01-19 2017-01-19
US62/447,992 2017-01-19
CN201780086503.7A CN110325196B (zh) 2016-12-20 2017-12-20 用于抑制癫痫发作的组合物和方法
PCT/US2017/067548 WO2018119048A1 (en) 2016-12-20 2017-12-20 Compositions and methods for inhibiting seizures

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201780086503.7A Division CN110325196B (zh) 2016-12-20 2017-12-20 用于抑制癫痫发作的组合物和方法

Publications (1)

Publication Number Publication Date
CN119033822A true CN119033822A (zh) 2024-11-29

Family

ID=62627881

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202411196564.7A Pending CN119033822A (zh) 2016-12-20 2017-12-20 用于抑制癫痫发作的组合物和方法
CN201780086503.7A Active CN110325196B (zh) 2016-12-20 2017-12-20 用于抑制癫痫发作的组合物和方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201780086503.7A Active CN110325196B (zh) 2016-12-20 2017-12-20 用于抑制癫痫发作的组合物和方法

Country Status (7)

Country Link
US (3) US11129858B2 (enExample)
EP (1) EP3558329B1 (enExample)
JP (1) JP7166280B2 (enExample)
CN (2) CN119033822A (enExample)
AU (1) AU2017382197B2 (enExample)
CA (1) CA3047397A1 (enExample)
WO (1) WO2018119048A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119033822A (zh) 2016-12-20 2024-11-29 加利福尼亚大学董事会 用于抑制癫痫发作的组合物和方法
JP6840272B2 (ja) * 2017-06-14 2021-03-10 フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited 細菌株を含む組成物
JP7520820B2 (ja) * 2018-09-20 2024-07-23 イェダ リサーチ アンド ディベロップメント カンパニー リミテッド 筋萎縮性側索硬化症の治療方法
CN113164527A (zh) * 2018-09-27 2021-07-23 芬奇治疗控股有限责任公司 用于治疗癫痫和相关障碍的组合物和方法
KR102340392B1 (ko) * 2018-10-08 2021-12-17 한국생명공학연구원 우울증의 예방 또는 치료 효과를 가지는 장내 미생물 및 이의 용도
CN110227085A (zh) * 2019-07-16 2019-09-13 江苏省中医院 Akkermansia Muciniphila在制备抗抑郁药物或者保健品中的应用
CN115916227A (zh) * 2020-06-12 2023-04-04 森永乳业株式会社 线粒体功能改善用组合物
CN113367328B (zh) * 2021-06-11 2023-02-21 无锡市人民医院 一种调节肠道菌群和能量代谢的多阶段生酮饮食配方
EP4373502A1 (en) * 2021-07-20 2024-05-29 Université catholique de Louvain Prevention and/or treatment of reward dysregulation disorders
WO2023001368A1 (en) * 2021-07-20 2023-01-26 Université Catholique de Louvain Prevention and/or treatment of reward dysregulation disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6461607B1 (en) 1998-08-24 2002-10-08 Ganeden Biotech, Inc. Probiotic, lactic acid-producing bacteria and uses thereof
WO2014075745A1 (en) * 2012-11-19 2014-05-22 Université Catholique de Louvain Use of akkermansia for treating metabolic disorders
CA2940226A1 (en) * 2013-02-22 2014-08-28 The Regents Of The University Of California Compositions and methods for promoting growth of beneficial microbes to treat or prevent disease or prolong life
KR101445243B1 (ko) * 2014-03-28 2014-09-29 서울대학교산학협력단 장내 세균의 군집과 기능의 변화를 이용한 대사성 및 염증성 질환의 조기진단
MA41020A (fr) * 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
KR20180010237A (ko) * 2015-05-21 2018-01-30 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 건강 증진을 위한 박테리아 집단
PT3297644T (pt) 2015-05-22 2022-03-30 Univ Arizona State Métodos para tratar distúrbios do espetro do autismo e sintomas associados
CN119033822A (zh) 2016-12-20 2024-11-29 加利福尼亚大学董事会 用于抑制癫痫发作的组合物和方法
US20220184084A1 (en) 2019-03-18 2022-06-16 The Regents Of The University Of California Compositions and methods for treating cushing's disease

Also Published As

Publication number Publication date
WO2018119048A1 (en) 2018-06-28
EP3558329B1 (en) 2024-01-31
US20200384037A1 (en) 2020-12-10
AU2017382197B2 (en) 2022-12-01
US11129858B2 (en) 2021-09-28
CA3047397A1 (en) 2018-06-28
AU2017382197A1 (en) 2019-07-04
US20240238350A1 (en) 2024-07-18
EP3558329C0 (en) 2024-01-31
EP3558329A1 (en) 2019-10-30
CN110325196B (zh) 2024-08-27
JP7166280B2 (ja) 2022-11-07
US12364717B2 (en) 2025-07-22
US11883441B2 (en) 2024-01-30
US20220184144A1 (en) 2022-06-16
JP2020502281A (ja) 2020-01-23
CN110325196A (zh) 2019-10-11
EP3558329A4 (en) 2020-07-22

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