CN118930653A - 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞 - Google Patents

包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞 Download PDF

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Publication number
CN118930653A
CN118930653A CN202411248075.1A CN202411248075A CN118930653A CN 118930653 A CN118930653 A CN 118930653A CN 202411248075 A CN202411248075 A CN 202411248075A CN 118930653 A CN118930653 A CN 118930653A
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seq
car
cells
cell
nucleic acid
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Chinese (zh)
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M·普勒
S·科多巴
S·托马斯
S·奥诺哈
A·W·基纳
M·费拉里
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Autolus Ltd
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Autolus Ltd
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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CN202411248075.1A 2018-08-13 2019-08-13 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞 Pending CN118930653A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB1813178.9 2018-08-13
GBGB1813178.9A GB201813178D0 (en) 2018-08-13 2018-08-13 Cell
PCT/GB2019/052275 WO2020035676A1 (en) 2018-08-13 2019-08-13 Car t-cells comprising an anti cd33, an anti cll1 and at least one further car anti cd123 and/or ftl3
CN201980053953.5A CN112566941B (zh) 2018-08-13 2019-08-13 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞

Related Parent Applications (1)

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CN201980053953.5A Division CN112566941B (zh) 2018-08-13 2019-08-13 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞

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CN118930653A true CN118930653A (zh) 2024-11-12

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Application Number Title Priority Date Filing Date
CN202411248075.1A Pending CN118930653A (zh) 2018-08-13 2019-08-13 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞
CN201980053953.5A Active CN112566941B (zh) 2018-08-13 2019-08-13 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞
CN202411248012.6A Pending CN118878688A (zh) 2018-08-13 2019-08-13 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞
CN202411247931.1A Pending CN118909124A (zh) 2018-08-13 2019-08-13 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN201980053953.5A Active CN112566941B (zh) 2018-08-13 2019-08-13 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞
CN202411248012.6A Pending CN118878688A (zh) 2018-08-13 2019-08-13 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞
CN202411247931.1A Pending CN118909124A (zh) 2018-08-13 2019-08-13 包含抗cd33，抗cll1和至少一个另外的抗cd123和/或flt3 car的car t细胞

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US (2) US20230330139A1 (enExample)
EP (1) EP3837284A1 (enExample)
JP (2) JP7416762B2 (enExample)
CN (4) CN118930653A (enExample)
AU (3) AU2019321066B2 (enExample)
CA (1) CA3109752A1 (enExample)
GB (1) GB201813178D0 (enExample)
WO (1) WO2020035676A1 (enExample)

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CN117715935A (zh) * 2021-07-30 2024-03-15 南京传奇生物科技有限公司 抗cd33抗体及其用途
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CN116018351A (zh) * 2021-08-16 2023-04-25 上海优替济生生物医药有限公司 靶向cd123的抗体、嵌合抗原受体及其用途
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CN117482246B (zh) * 2022-12-30 2024-10-15 英百瑞(杭州)生物医药有限公司 抗cd33/cll1双特异性抗体-自然杀伤细胞偶联物及其用途
CN117964760B (zh) * 2023-12-21 2024-09-03 四川大学华西医院 抗人cll1/cd3的双特异性抗体及其应用
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