CN1185934C - Disinfectant lotion for body's vulva and vagina - Google Patents
Disinfectant lotion for body's vulva and vagina Download PDFInfo
- Publication number
- CN1185934C CN1185934C CNB021338841A CN02133884A CN1185934C CN 1185934 C CN1185934 C CN 1185934C CN B021338841 A CNB021338841 A CN B021338841A CN 02133884 A CN02133884 A CN 02133884A CN 1185934 C CN1185934 C CN 1185934C
- Authority
- CN
- China
- Prior art keywords
- vulva
- vagina
- disinfectant
- lotion
- disinfection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention provides disinfection wash liquid for body's vulva and vagina, which comprises the components of the following proportion by weight percentage: 0.1 to 0.3% of triclosan, 2 to 10% of propanediol, 2 to 15% of propanetriol, 1 to 15% of ethanol, 0.01 to 0.1% of helveticoside, 0.01 to 0.1% of matrine, 0.01 to 0.1% of osthole and rest percentage of water. The disinfection wash liquid can rapidly kill pathogenic bacteria of staphylococcus aureus, coliform bacteria, monilia albicans, etc., and has good disinfection effects.
Description
Technical field:
What the present invention relates to is a kind of disinfectant lotion, particularly be a kind of disinfectant lotion that is used for body's vulva and vagina.
Background technology:
People's clean your the moon commonly used carries out disinfection to V﹠V.
Summary of the invention:
The objective of the invention is to kill pathogenic bacteria such as Staphylococcus aureus, Escherichia coli, Candida albicans, the disinfectant lotion that is used for body's vulva and vagina that Disinfection Effect is good rapidly in order to provide a kind of.
The object of the present invention is achieved like this:
The present invention is used for the disinfectant lotion of body's vulva and vagina, comprises following component by weight percentage:
Triclosan 0.1～0.3%
Propane diols 2～10%
Glycerine 2～15%
Ethanol 1～15%
Berberine 0.01～0.1%
Matrine 0.01～0.1%
Osthole 0.01～0.1%
Distilled water surplus.
Disinfectant lotion of the present invention is to be main sterilization component with triclosan, and it is formulated to be aided with the berberine of assisting sterilisation, antipruritic matrine, bactericidal antiphlogistic antipruritic Osthole, the glycerine of skin moisten, the propane diols of making solvent, ethanol and thinner distilled water.Through Sichuan Province health and epidemic prevention station test, this washing lotion pathogenic bacteria (seeing Table 1～table 3) such as Staphylococcus aureus, Escherichia coli, Candida albicans of going out rapidly, Disinfection Effect is good, avirulence, non-stimulated (table 4～table 5).
Table 1: to the killing effect of staphylococcus aureus
The average kill ratio of drug concentration effect different time (min) and scope (%)
(％) 5 10 15 20
99.95 99.99 99.99 100.00
40 (99.93～99.96) (99.97～99.99) (99，99～100.00)
99.55 99.94 99.99 99.99
20 (99.48～99.63) (99.92～99.96) (99.98～99.99) (99.99～99.99)
99.19 99.77 99.94 99.99
10 (99.02～99.39) (99.60～99.87) (99.93～99.96) (99.99～99.99)
The average bacterium number of positive controls is 1.930 * 10
6(1.700 * 10
6～2.150 * 10
6) the cfu/ sheet.
The negative control group asepsis growth.
Conclusion:
1, under the support methods experimental condition with 1% lecithin+1% Tween-80+1% glycine+0.5%Na
2S
2O
3PBS solution as neutralizer, residual this disinfectant 40% concentration that can effectively neutralize is to the killing action of staphylococcus aureus, and this neutralizer does not have influence to growth and breeding and the medium of staphylococcus aureus.
2, adopt support methods under 20 ± 2 ℃ of temperature, this disinfectant 40% concentration acts on 5min to staphylococcus aureus, and killing rate is 99.95% (99.93%～99.96%), and 10% mass action 15min, killing rate are 99.94% (99.93%～99.96%).
Table 2: to colibacillary killing effect
The average kill ratio of drug concentration effect different time (min) and scope (%)
(％) 5 10 15 20
99.99 99.99 100.00 100.00
20 (99.98～99.99) (99.99～99.99)
99.96 99.99 99.99 100.00
10 (99.94～99.97) (99.99～99.99) (99.99～100.00)
99.86 99.94 99.99 99.99
5 (99.85～99.88) (99.92～99.97) (99.99～99.99) (99.99～100.00)
The average bacterium number of positive controls is 1.700 * 10
6(1.500 * 10
6～1.950 * 10
6) the cfu/ sheet.
The negative control group asepsis growth.
Conclusion:
Adopt support methods under 20 ± 2 ℃ of temperature, this disinfectant 10% concentration acts on 5min to Escherichia coli, and killing rate is 99.96% (99.94%～99.97%), and 5% mass action 10min, killing rate are 99.94% (99.92%～99.97%).
Table 3: to the oidiomycetic killing effect of white
The average kill ratio of drug concentration effect different time (min) and scope (%)
(％) 5 10 15 20
99.95 99.99 99.99 100.00
80 (99.94～99.96) (99.99～99.99) (99.99～100.00)
99.67 99.95 99.99 100.00
60 (99.55～99.87) (99.95～99.94) (99.99～99.99)
99.88 99.72 99.93 99.99
40 (98.55～99.08) (99.66～99.79) (99.92～99.94) (99.99～99.99)
The average bacterium number of positive controls is 1.600 * 10
6(1.350 * 10
6～1.800 * 10
6) the cfu/ sheet.
The negative control group asepsis growth.
Conclusion:
1, under the support methods experimental condition with 1% lecithin+1% Tween-80+1% glycine+0.5%Na
2S
2O
3PBS solution as neutralizer, residual this disinfectant 80% concentration that can effectively neutralize is to the oidiomycetic killing action of white, and this neutralizer does not have influence to oidiomycetic growth and breeding of white and medium.
2, adopt support methods under 20 ± 2 ℃ of temperature, this disinfectant 80% concentration is to Candida albicans effect 5min, and killing rate is 99.95% (99.94%～99.96%), and 40% mass action 15min, killing rate are 99.93% (99.92%～99.94%).
Table 4: thousand pure as jade board disinfectant lotion chmice acute per os toxicity test results
| The property dosetest number of animals dead animal count lethality (mg/kg) (only) (only) be not (%) |
| 1,000 500 2,150 500 female 4,640 500 10,000 500 |
| 1,000 500 2,150 500 male 4,640 500 10,000 500 |
Conclusion:
Thousand pure as jade board disinfectant lotions are to chmice acute per os toxicity test result, LD
50Value is pressed the classification of chemical substance acute toxicity greater than 10000mg/kg, the nontoxic level in true border.
Table 5:
Moving 1h 24h 48h
The contrast of rerum natura body sample control sample control sample
Compile not Chong the total red water of the total red water of the total red water of the total red water of the total red water of red water total
Number (kg) spot is swollen to divide that spot is swollen to divide that spot is swollen to divide that spot is swollen to divide that spot is swollen to divide that spot is swollen to be divided
1 female 2.5 000000000000000000
2 female 2.3 000000000000000000
3 male 2.4 000000000000000000
4 male 2.3 000000000000000000
Total mark average 000000000000000000
Inflammatory reactions such as erythema, oedema all do not appear in all rabbit skins, and the acute skin irritation index is 0.
Conclusion: thousand pure as jade board disinfectant lotions are to rabbit skin nonirritant.
Sterilized stock solution effect of the present invention is natural bacteria 3min on hand, and elimination factor is 91.25% (90.40%～100.00%), and it is 26 people that residual on hand bacterium number reaches the national standard number, and residual bacterium is counted scope: 0～500cfu/ hand.
Embodiment:
Disinfectant lotion embodiment of the present invention sees Table 6:
Table 6:
The production technology of the various embodiments described above is as follows:
1., batching;
2., triclosan is put into ethanol, propane diols, glycerine, fully stirring and evenly mixing;
3., berberine, matrine, Osthole are put into, fully stirring is mixed;
4., adding distil water mixes;
5., put only, filtration, can, packing, finished product warehouse-in.
Claims (1)
1, the disinfectant lotion that is used for body's vulva and vagina is characterized in that comprising by weight percentage following component:
Triclosan 0.1～0.3%
Propane diols 2～10%
Glycerine 2～15%
Ethanol 1～15%
Berberine 0.01～0.1%
Matrine 0.01～0.1%
Osthole 0.01～0.1%
Distilled water surplus.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021338841A CN1185934C (en) | 2002-10-10 | 2002-10-10 | Disinfectant lotion for body's vulva and vagina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021338841A CN1185934C (en) | 2002-10-10 | 2002-10-10 | Disinfectant lotion for body's vulva and vagina |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1402981A CN1402981A (en) | 2003-03-19 |
| CN1185934C true CN1185934C (en) | 2005-01-26 |
Family
ID=4747448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021338841A Expired - Lifetime CN1185934C (en) | 2002-10-10 | 2002-10-10 | Disinfectant lotion for body's vulva and vagina |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1185934C (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102512434A (en) * | 2011-12-28 | 2012-06-27 | 王爽 | Combination drug used for killing genitals microorganisms of female Tibetan mastiffs and assisting reproduction |
| CN103372039B (en) * | 2012-04-26 | 2018-01-05 | 中国人民解放军第二军医大学 | Frutus cnidii cumarin is used for the purposes for preparing antifungal medicament synergist product |
| CA2897038C (en) | 2014-07-14 | 2016-10-04 | Novicol International Holding Inc. | Microbicidal composition comprising an octoxynol and a quinolizidine alkaloid compound or a source thereof |
| CN106538608A (en) * | 2016-09-29 | 2017-03-29 | 四川三和医用材料有限公司 | A kind of medical glovess disinfectant solution |
-
2002
- 2002-10-10 CN CNB021338841A patent/CN1185934C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1402981A (en) | 2003-03-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1169529C (en) | Nanometer silver antimicrobial inflammation-relieving gel for curing prostatitis and its industrial production process | |
| CN101642449B (en) | Skin mucous membrane disinfectants and preparation method thereof | |
| CN101076256A (en) | Antimicrobial food additive and prepared food, water and waste water treatment | |
| CN101053330A (en) | Disinfectant for improving hydrogen peroxide bactericidal activity | |
| CN101744004B (en) | Attapulgite chlorine dioxide antiseptic disinfectant | |
| CN1788568A (en) | Quick-effective iodine disinfectant and production method thereof | |
| CN101053568A (en) | Compound and its processing technology for compound sulfamonomethoxine sodium injection | |
| CN114831137B (en) | Deodorant with antibacterial effect | |
| CN1185934C (en) | Disinfectant lotion for body's vulva and vagina | |
| CN111467249A (en) | Washing-free antibacterial gel and preparation method thereof | |
| CN1131068C (en) | Composite lysostaphin enzyme spray for oral cavity and its preparing process | |
| CN1369206A (en) | Nano Silver sterilizing gel, its preparing method and use | |
| CN1309304C (en) | Sterilizing gel, preparing method and application thereof | |
| CN1415209A (en) | Method for preparing the bactericide and the cleansing facial milk] | |
| CN1524587A (en) | Nursing wet towel using tea plant oil as antibacterial and fungistatic agent and production method thereof | |
| CN1286373C (en) | Propolis-silver ion composite nanometer disinfectant and preparation method thereof | |
| CN111840100A (en) | Antibacterial washing and protecting liquid based on antibacterial carbon nanodots, and preparation method and application thereof | |
| CN1327741A (en) | Compound lysostaphin enzyme disinfectant | |
| CN1484959A (en) | Sterilization formulation and wet tissue, preparation method and use | |
| CN1895672A (en) | Multifunctional broad-spectrum obtundent of polyphyletic synergistic and its use | |
| CN1853480A (en) | Broad-spectrum antiseptics and production thereof | |
| CN1188132C (en) | Medicine for inhibiting and killing body's superficial pathogenic fungi | |
| CN1309305C (en) | Chinese herbal medicine air disinfectant | |
| CN1279939C (en) | Medicinal spraying agent for treating nasitis | |
| CN100345559C (en) | Medicine from black snake for treating vitiligo |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: RUNXING STERILIZATION PHARMA IND CO., LTD., CHENGD Free format text: FORMER OWNER: YU JINGRU Effective date: 20110212 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 610041 NO.4, 2/F, UNIT 2, BUILDING 61, NO.20, SHAYAN WEST STREET 2, WUHOU DISTRICT, CHENGDU CITY, SICHUAN PROVINCE TO: 610061 GUIXI INDUSTRIAL PARK, NEW AND HIGH TECHNOLOGY ZONE, CHENGDU, SICHUAN PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20110212 Address after: 610061 Sichuan Province, Chengdu high tech Zone Guixi Industrial Park Patentee after: CHENGDU ROSUN DISINFECTION PHARMACEUTICAL CO.,LTD. Address before: 610041, No. 2, building 2, 61, building 20, two West Street, 4 West sand weir, Sichuan, Wuhou District, Chengdu Patentee before: Yu Jingru |
|
| CX01 | Expiry of patent term |
Granted publication date: 20050126 |
|
| CX01 | Expiry of patent term |