CN118475700A - 温度敏感性的负链rna病毒或病毒载体及其rna基因组 - Google Patents

温度敏感性的负链rna病毒或病毒载体及其rna基因组 Download PDF

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CN118475700A
CN118475700A CN202280085608.1A CN202280085608A CN118475700A CN 118475700 A CN118475700 A CN 118475700A CN 202280085608 A CN202280085608 A CN 202280085608A CN 118475700 A CN118475700 A CN 118475700A
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protein
virus
mutations
amino acids
mutation
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Chinese (zh)
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佐伯晃一
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Lifuli Technology Co ltd
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Lifuli Technology Co ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18821—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18822—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18841—Use of virus, viral particle or viral elements as a vector
    • C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202280085608.1A 2021-12-27 2022-12-27 温度敏感性的负链rna病毒或病毒载体及其rna基因组 Pending CN118475700A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021-213114 2021-12-27
JP2021213114 2021-12-27
PCT/JP2022/048141 WO2023127871A1 (ja) 2021-12-27 2022-12-27 温度感受性のマイナス鎖ｒｎａウイルスまたはウイルスベクターおよびそのｒｎａゲノム

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CN118475700A true CN118475700A (zh) 2024-08-09

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CN202280085608.1A Pending CN118475700A (zh) 2021-12-27 2022-12-27 温度敏感性的负链rna病毒或病毒载体及其rna基因组

Country Status (7)

Country Link
US (1) US20250333760A1 (cg-RX-API-DMAC7.html)
EP (1) EP4458974A4 (cg-RX-API-DMAC7.html)
JP (2) JPWO2023127871A1 (cg-RX-API-DMAC7.html)
CN (1) CN118475700A (cg-RX-API-DMAC7.html)
AU (1) AU2022424476A1 (cg-RX-API-DMAC7.html)
CA (1) CA3243062A1 (cg-RX-API-DMAC7.html)
WO (1) WO2023127871A1 (cg-RX-API-DMAC7.html)

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Publication number Priority date Publication date Assignee Title
CN121057822A (zh) * 2023-03-22 2025-12-02 礼富利科技股份有限公司 温度敏感性的负链rna病毒或病毒载体及其rna基因组
WO2025033445A1 (ja) 2023-08-07 2025-02-13 株式会社Logomix 遺伝子をコンディショナルに不活化させる方法、およびそのための細胞

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4206154B2 (ja) 1997-11-13 2009-01-07 大日本住友製薬株式会社 変異型ｌｏｘＰ配列とその応用
JP4787440B2 (ja) 1999-09-30 2011-10-05 泉 斎藤 変異型ｆｒｔ配列を含有してなるｄｎａ
US20050130123A1 (en) * 2001-09-18 2005-06-16 Makoto Inoue Methods of examining (-) strand rna virus vectors having lowered ability to form grains and method of constructing the same
CA2554198A1 (en) 2004-01-22 2005-08-04 Dnavec Research Inc. Process for producing virus vector
EP2434020B1 (en) 2004-01-22 2014-11-05 Dnavec Research Inc. Method of producing Paramyxoviridae viral vectors using a hybrid promoter comprising a cytomegalovirus enhancer and a chicken beta-actin promoter
JP2006180780A (ja) * 2004-12-27 2006-07-13 National Institute Of Advanced Industrial & Technology 持続感染型センダイウイルスベクター
US8173792B2 (en) 2007-02-09 2012-05-08 The Board Of Trustees Of The Leland Stanford Junior University Method for regulating protein function in cells using synthetic small molecules
US8530636B2 (en) * 2008-05-07 2013-09-10 The Board Of Trustees Of The Leland Stanford Junior University Method for regulating protein function in cells in vivo using synthetic small molecules
WO2010008054A1 (ja) * 2008-07-16 2010-01-21 ディナベック株式会社 染色体非組み込み型ウイルスベクターを用いてリプログラムされた細胞を製造する方法
US9090909B2 (en) * 2010-08-30 2015-07-28 Dnavec Corporation Composition for inducing pluripotent stem cell, and use thereof
JP6769880B2 (ja) * 2015-02-02 2020-10-14 株式会社Ｉｄファーマ 改良されたマイナス鎖ｒｎａウイルスベクター
DK3375874T3 (da) * 2015-11-13 2022-05-09 Id Pharma Co Ltd Forbedret paramyxovirus-vektor

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Publication number Publication date
CA3243062A1 (en) 2025-04-16
JP2025081483A (ja) 2025-05-27
AU2022424476A1 (en) 2024-07-11
JPWO2023127871A1 (cg-RX-API-DMAC7.html) 2023-07-06
EP4458974A4 (en) 2026-05-20
EP4458974A1 (en) 2024-11-06
US20250333760A1 (en) 2025-10-30
WO2023127871A1 (ja) 2023-07-06

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