AU2022424476A1 - Temperature-sensitive negative-strand RNA virus or virus vector and RNA genome thereof - Google Patents

Temperature-sensitive negative-strand RNA virus or virus vector and RNA genome thereof Download PDF

Info

Publication number
AU2022424476A1
AU2022424476A1 AU2022424476A AU2022424476A AU2022424476A1 AU 2022424476 A1 AU2022424476 A1 AU 2022424476A1 AU 2022424476 A AU2022424476 A AU 2022424476A AU 2022424476 A AU2022424476 A AU 2022424476A AU 2022424476 A1 AU2022424476 A1 AU 2022424476A1
Authority
AU
Australia
Prior art keywords
virus
protein
amino acid
cell
negative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2022424476A
Other languages
English (en)
Inventor
Koichi Saeki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Repli-tech Co Ltd
Original Assignee
Repli-tech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Repli-tech Co Ltd filed Critical Repli-tech Co Ltd
Publication of AU2022424476A1 publication Critical patent/AU2022424476A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18821—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18822—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18841—Use of virus, viral particle or viral elements as a vector
    • C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2022424476A 2021-12-27 2022-12-27 Temperature-sensitive negative-strand RNA virus or virus vector and RNA genome thereof Pending AU2022424476A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021-213114 2021-12-27
JP2021213114 2021-12-27
PCT/JP2022/048141 WO2023127871A1 (ja) 2021-12-27 2022-12-27 温度感受性のマイナス鎖rnaウイルスまたはウイルスベクターおよびそのrnaゲノム

Publications (1)

Publication Number Publication Date
AU2022424476A1 true AU2022424476A1 (en) 2024-07-11

Family

ID=86998996

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2022424476A Pending AU2022424476A1 (en) 2021-12-27 2022-12-27 Temperature-sensitive negative-strand RNA virus or virus vector and RNA genome thereof

Country Status (7)

Country Link
US (1) US20250333760A1 (cg-RX-API-DMAC7.html)
EP (1) EP4458974A4 (cg-RX-API-DMAC7.html)
JP (2) JPWO2023127871A1 (cg-RX-API-DMAC7.html)
CN (1) CN118475700A (cg-RX-API-DMAC7.html)
AU (1) AU2022424476A1 (cg-RX-API-DMAC7.html)
CA (1) CA3243062A1 (cg-RX-API-DMAC7.html)
WO (1) WO2023127871A1 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121057822A (zh) * 2023-03-22 2025-12-02 礼富利科技股份有限公司 温度敏感性的负链rna病毒或病毒载体及其rna基因组
WO2025033445A1 (ja) 2023-08-07 2025-02-13 株式会社Logomix 遺伝子をコンディショナルに不活化させる方法、およびそのための細胞

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4206154B2 (ja) 1997-11-13 2009-01-07 大日本住友製薬株式会社 変異型loxP配列とその応用
JP4787440B2 (ja) 1999-09-30 2011-10-05 泉 斎藤 変異型frt配列を含有してなるdna
US20050130123A1 (en) * 2001-09-18 2005-06-16 Makoto Inoue Methods of examining (-) strand rna virus vectors having lowered ability to form grains and method of constructing the same
CA2554198A1 (en) 2004-01-22 2005-08-04 Dnavec Research Inc. Process for producing virus vector
EP2434020B1 (en) 2004-01-22 2014-11-05 Dnavec Research Inc. Method of producing Paramyxoviridae viral vectors using a hybrid promoter comprising a cytomegalovirus enhancer and a chicken beta-actin promoter
JP2006180780A (ja) * 2004-12-27 2006-07-13 National Institute Of Advanced Industrial & Technology 持続感染型センダイウイルスベクター
US8173792B2 (en) 2007-02-09 2012-05-08 The Board Of Trustees Of The Leland Stanford Junior University Method for regulating protein function in cells using synthetic small molecules
US8530636B2 (en) * 2008-05-07 2013-09-10 The Board Of Trustees Of The Leland Stanford Junior University Method for regulating protein function in cells in vivo using synthetic small molecules
WO2010008054A1 (ja) * 2008-07-16 2010-01-21 ディナベック株式会社 染色体非組み込み型ウイルスベクターを用いてリプログラムされた細胞を製造する方法
US9090909B2 (en) * 2010-08-30 2015-07-28 Dnavec Corporation Composition for inducing pluripotent stem cell, and use thereof
JP6769880B2 (ja) * 2015-02-02 2020-10-14 株式会社Idファーマ 改良されたマイナス鎖rnaウイルスベクター
DK3375874T3 (da) * 2015-11-13 2022-05-09 Id Pharma Co Ltd Forbedret paramyxovirus-vektor

Also Published As

Publication number Publication date
CA3243062A1 (en) 2025-04-16
JP2025081483A (ja) 2025-05-27
CN118475700A (zh) 2024-08-09
JPWO2023127871A1 (cg-RX-API-DMAC7.html) 2023-07-06
EP4458974A4 (en) 2026-05-20
EP4458974A1 (en) 2024-11-06
US20250333760A1 (en) 2025-10-30
WO2023127871A1 (ja) 2023-07-06

Similar Documents

Publication Publication Date Title
ES2726766T3 (es) Método para el desarrollo eficiente de células madre pluripotentes inducidas
CN102159710B (zh) 使用染色体非整合型病毒载体制造经初始化的细胞的方法
JP2025081483A (ja) 温度感受性のマイナス鎖rnaウイルスまたはウイルスベクターおよびそのrnaゲノム
EP4121535A1 (en) Compositions and methods for the targeting of c9orf72
EP4028522A1 (en) Compositions and methods for the targeting of sod1
JP2019122398A (ja) ヒト細胞を若返らせるためのzscan4の使用方法
JP6927883B2 (ja) 改良されたパラミクソウイルスベクター
US20150184131A1 (en) Enhanced Efficiency of Induced Pluripotent Stem Cell Generation
US20260132420A1 (en) Viral vectors for nuclear reprogramming
CN101646768A (zh) 减毒负链rna病毒
Warren et al. Feeder‐free reprogramming of human fibroblasts with messenger RNA
JPWO2017209290A1 (ja) 多能性幹細胞由来運動ニューロンの製造及びその用途
HK40117834A (en) Temperature-sensitive minus-strand rna virus or virus vector and rna genome thereof
EP4685236A1 (en) Temperature-sensitive negative-strand rna virus or viral vector and rna genome thereof
WO2016056438A1 (ja) 心筋様細胞の作製方法及びそれに用いる心筋様細胞の作製用組成物
JP7808298B2 (ja) iPS細胞の品質改善剤、iPS細胞の製造方法、iPS細胞、及びiPS細胞製造用組成物
JP2004344001A (ja) 胚性幹細胞に遺伝子を導入する方法
HK40080409A (en) Viral vectors for nuclear reprogramming
WO2019017438A1 (ja) 標的配列を改変するためのポリヌクレオチドおよびその使用