CN118178517A - Oil-control acne-removing composition and preparation method and application thereof - Google Patents
Oil-control acne-removing composition and preparation method and application thereof Download PDFInfo
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Abstract
The invention relates to the technical field of traditional Chinese medicines and cosmetics, and discloses an oil-control acne-removing composition, and a preparation method and application thereof, wherein the composition comprises the following components in parts by weight: 18-32 parts of loquat leaf, 9-17 parts of red sage root, 4-11 parts of pseudo-ginseng, 15-26 parts of astragalus root, 6-13 parts of magnolia bark, 3-9 parts of fructus cannabis, 5-12 parts of Chinese fevervine herb and 10-16 parts of rhizoma atractylodis. The preparation method comprises preparing folium Eriobotryae extract, rhizoma Atractylodis extract, saviae Miltiorrhizae radix extract, notoginseng radix extract, radix astragali extract, cortex Magnolia officinalis extract, fructus Cannabis volatile oil and herba Paederiae volatile oil, and mixing to obtain oil-controlling acne-removing composition. The invention takes loquat leaves, red sage roots and pseudo-ginseng as monarch drugs, astragalus root, fructus cannabis as ministerial drugs, magnolia officinalis and rhizoma atractylodis as adjuvant and guide drugs. The monarch, minister, assistant and guide, and the synergistic effect can treat the symptoms and remove the acne which has grown; but also treats the root cause, adjusts the skin quality of the patient, eliminates the damp-heat of the skin and eliminates the possibility of oil discharge and acne recurrence of the skin.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines and cosmetics, and particularly relates to an oil-control acne-removing composition, and a preparation method and application thereof.
Background
Acne is commonly known as acne, and is also called pimple, acne, thorn or pimple. Acne is one of the most common diseases of cosmetic skin, is a chronic inflammation of pilo-sebaceous glands, is usually well developed on the face, neck, chest and back and the like, can form pits and marks on the skin surface, and has great influence on the psychological and social activities of patients. The products used for clinically treating acne mainly comprise external vitamin A acid medicines, benzoyl peroxide or external antibiotics, and the like, and the excessive skin can generate irritation reactions such as allergy, local erythema, desquamation, burning sensation and the like, thereby causing secondary injury to the skin. The pathogenic bacteria causing acne are propionibacterium acnes, which are resistant and cross-resistant to a variety of antibiotics, which currently do not completely clear propionibacterium acnes.
The prior art discloses an anti-inflammatory acne-removing cream (refer to Chinese patent CN 114569505B), which comprises the following components in parts by weight: 40 to 65 parts of water, 9 to 15 parts of humectant, 4 to 6 parts of thickener, 3 to 6 parts of emulsifier, 8 to 12 parts of emollient, 0.4 to 0.9 part of preservative, 0.02 to 0.05 part of aromatic, 0.1 to 0.4 part of cooling agent, 0.2 to 0.8 part of pH regulator, 1.8 to 3.6 parts of mountain lettuce polyphenol/lignin microsphere and 2 to 7 parts of skin conditioner. Although the acne-removing cream can diminish inflammation and remove acnes, the acne-removing cream only aims at the acnes which are already grown, can not internally regulate the skin balance of a patient, fundamentally reduces the possibility of relapse, and achieves the effect of treating both symptoms and root causes.
Disclosure of Invention
The invention provides an oil-control acne-removing composition, a preparation method and application thereof, and solves the problems that although acne-removing paste prepared by the prior art can diminish inflammation and remove acnes, the acne-removing paste only aims at eliminating the existing acnes, cannot fundamentally adjust skin balance and reduces the possibility of recurrence.
The oil-control acne-removing composition comprises the following components in parts by weight: 18-32 parts of loquat leaf, 9-17 parts of red sage root, 4-11 parts of pseudo-ginseng, 15-26 parts of astragalus root, 6-13 parts of magnolia bark, 3-9 parts of fructus cannabis, 5-12 parts of Chinese fevervine herb and 10-16 parts of rhizoma atractylodis.
Preferably, the composition comprises the following raw materials in parts by weight: 22-28 parts of loquat leaf, 12-14 parts of red sage root, 6-9 parts of pseudo-ginseng, 18-23 parts of astragalus root, 8-11 parts of magnolia officinalis, 5-7 parts of fructus cannabis, 7-9 parts of Chinese fevervine herb and 12-14 parts of rhizoma atractylodis.
Preferably, the composition comprises the following components in parts by weight: 25 parts of loquat leaf, 13 parts of red sage root, 8 parts of pseudo-ginseng, 21 parts of astragalus root, 9 parts of magnolia officinalis, 6 parts of fructus cannabis, 8 parts of Chinese fevervine herb and 13 parts of rhizoma atractylodis.
The second purpose of the invention is to protect the preparation method of the oil-control acne-removing composition, which specifically comprises the following steps:
Preparing a loquat leaf extract: pulverizing folium Eriobotryae according to the formula amount, decocting in water for 30-45 min, filtering, and concentrating the filtrate to obtain folium Eriobotryae extract; the preparation method of the rhizoma atractylodis extract is the same as that of the loquat leaf extract;
preparing a red sage root extract: slicing the red sage root with the formula amount, adding water for decoction for 1-1.5 h, filtering and concentrating to obtain the red sage root extract;
The preparation methods of the pseudo-ginseng extract and the astragalus extract are the same as the preparation method of the red sage root extract;
preparing magnolia bark extract: pulverizing cortex Magnolia officinalis, adding 70% ethanol, refluxing at 75-80deg.C for 40-70 min, centrifuging to obtain supernatant, and concentrating to obtain cortex Magnolia officinalis extract;
Preparing fructus cannabis volatile oil: shelling fructus Cannabis according to the formula amount, pulverizing to 80-120 meshes, soaking in 70% ethanol water solution for 4-6 h, homogenizing, ultrasonic treating, filtering, extracting, and concentrating to obtain fructus Cannabis volatile oil; wherein the mass ratio of the hemp seed to the ethanol is 70 percent=1:2-3;
Preparing herba Paederiae volatile oil: pulverizing herba Paederiae, soaking in 70% ethanol water solution for 12-24 hr, ultrasonic treating, filtering, extracting, and concentrating to obtain herba Paederiae volatile oil; wherein the mass ratio of the Chinese fevervine herb to the 70% ethanol=1:4-6;
Mixing the prepared loquat leaf extract, rhizoma atractylodis extract, red sage root extract, pseudo-ginseng extract, astragalus extract, magnolia bark extract, fructus cannabis volatile oil and paederia scandens volatile oil to obtain the oil-control acne-removing composition.
Preferably, the loquat leaf comprises water=1g:7ml.
Preferably, in preparing the magnolia bark extract, the centrifugation conditions are: centrifuging at 5000-8000 rpm/min for 10-15 min.
Preferably, when preparing the hemp seed volatile oil, the homogenization power is 185W, and the rotating speed is 8000-10000 r/min.
Preferably, when the hemp seed volatile oil is prepared, the ultrasonic power is 500W, the temperature is 50-60 ℃ and the time is 30-45 min.
The third purpose of the invention is to protect the oil-control acne-removing composition from being used for preparing skin care products.
Preferably, the skin care product comprises oil control acne removal face cream, oil control acne removal mask and oil control acne removal water. When the skin care product is an oil-control acne-removing cream, the skin care product comprises the following raw materials in parts by weight: 10 parts of oil control acne removal composition and 10 parts of Vaseline; when the skin care product is an oil control acne removal mask, the skin care product comprises the following raw materials in parts by weight: 10 parts of oil control acne removal composition and 10 parts of honey; when the skin care product is oil control acne removal water, the skin care product comprises the following raw materials in parts by weight: 10 parts of oil control acne removal composition and 5 parts of deionized water.
Pharmacological action of the raw materials:
Loquat leaves: bitter in flavor and descending in blood, clear in cold, enter the lung and stomach meridians. It is indicated for cough and dyspnea due to lung heat and vomiting due to stomach heat, because it can clear heat from lung and stomach and reduce qi of lung and stomach.
Root of red-rooted salvia: danshen is bitter in flavor and can dispel heat, clear slightly cold and enter heart and liver meridians. Not only activating blood and removing stasis to relieve pain, but also refreshing and cooling blood to relieve restlessness and remove carbuncle, and is mainly indicated for blood stasis, blood heat and heat disturbing heart-mind syndromes, and also for sore and abscess swelling and pain due to heat toxin. Gu Yun "Yiwei Danshen san, a decoction of four ingredients, is a kind of herb for cooling blood, activating blood, removing stasis and promoting tissue regeneration.
Pseudo-ginseng: slightly bitter and loose powder, sweet and tonic, warm and general, and middle energizer-discharging and stomach meridians. Has strong hemostatic and stasis resolving effects, and can tonify deficiency, has the advantages of stopping bleeding without retaining stasis, promoting blood circulation without consuming qi, is effective for oral administration and external use, can be administered after hemorrhage and stasis swelling, is most suitable for people with cold and deficiency, and is suitable for people with heat without deficiency for clearing heat and cooling blood and corresponding products.
Radix astragali: gan Wenbu liters of astragalus root, sweet and bland, and excreted; it is used with mild condition and stir-baked with honey to warm the spleen and lung meridians, strengthen body resistance and remove pathogenic factors. It is good at tonifying middle-jiao qi, promoting the production of qi and clearing yang, tonifying lung qi, invigorating stomach and consolidating exterior, and can be used for treating spleen-lung qi deficiency, sinking of middle-jiao qi, qi failing to control blood, spontaneous perspiration and night sweat, etc., and also for treating sore, carbuncle, non-ulcer or chronic ulcer due to qi and blood deficiency, qi deficiency and edema, dysuria.
Cortex Magnoliae officinalis: the magnolia bark, cortex magnoliae officinalis, bitter in flavor, has the effects of draining and descending, pungent and dispersed, warmly communicating, entering spleen, stomach and large intestine channels, not only removing dampness stagnation in stomach and intestine and food stagnation, it is also indicated for abdominal distention and fullness due to damp obstruction, food stagnation and qi stagnation because it also regulates qi stagnation in stomach and intestine. It enters lung meridian, can lower qi and remove phlegm-dampness to relieve dyspnea, and is commonly indicated for cough and dyspnea with excessive phlegm.
Fructus cannabis: the Chinese medicinal material fructus cannabis has sweet and flat properties. Enter spleen, stomach and large intestine meridians. Has effects of loosening bowel to relieve constipation, and is mainly used for constipation due to blood deficiency and fluid deficiency and intestinal dryness.
Herba Paederiae: paederia scandens is sweet in taste and slightly bitter in flavor and is neutral in nature. Herba Paederiae has effects of resolving food stagnation, invigorating stomach, eliminating phlegm, relieving cough, clearing heat, detoxicating, and relieving pain.
Rhizoma atractylodis: the rhizoma atractylodis is bitter, dry and pungent and is fragrant and warm. Entering spleen and stomach meridians, it is indicated for spleen-qi stagnation due to cold-dampness, because it can dry dampness and strengthen spleen; it is indicated for arthralgia due to wind-cold-dampness and exterior syndrome with damp-dampness due to cold-dampness dispelling and arthralgia-relieving.
Compared with the prior art, the invention has the beneficial effects that:
the acne is essentially the residue deposited on the face which is not cleaned, and is caused by unsmooth qi and blood circulation and blockage of the face. Traditional Chinese medicine considers that the heart must be strengthened to smooth the qi and blood circulation of the face, because the heart governs blood vessels. The heart has strong function, the blood vessels of the whole body are unobstructed, the heart has weak function, the qi and blood circulation is slow, and stasis is formed. Meanwhile, the damp-heat of the body of the patient needs to be removed, and the damp-heat also causes oil and acne.
The application takes loquat leaves, red sage roots and pseudo-ginseng as monarch drugs, astragalus root, fructus cannabis as ministerial drugs, magnolia officinalis and rhizoma atractylodis as adjuvant and guide drugs. Loquat leaf, folium Eriobotryae, bitter and cold in nature, can lower lung qi and clear lung fire. The traditional Chinese medicine considers that all sores and pain and itch belong to the heart, so acne removal is required to treat heart, red sage root supplements heart blood, pseudo-ginseng activates blood to remove blood stasis, and the blood stasis is removed while the heart is supplemented. Astragalus root, radix astragali, with white color, is especially good at tonifying lung qi and can also remove necrotic tissue and promote tissue regeneration; hemp seed cleans small intestine and Chinese fevervine herb cleans large intestine; because the heart and the small intestine are both exterior and interior, clearing the small intestine can relieve the pressure of the heart, and the lung and the large intestine are both exterior and interior, clearing the large intestine can relieve the pressure of the lung. Meanwhile, the hemp seed oil and the Chinese fevervine herb oil are used, and the oil has the effect of relaxing bowel and further promotes the small intestine and the large intestine to discharge garbage. The magnolia bark moves qi to remove dampness, and the dampness is discharged through the stool. The rhizoma atractylodis is pungent and warm, can be dispersed, can walk the exterior, can solve the damp evil of spleen and stomach in middle-jiao, and can remove the damp evil on the surface of skin, so the rhizoma atractylodis is externally used, and has good dampness eliminating effect. The monarch, minister, assistant and guide, and the synergistic effect can treat the symptoms and remove the acne which has grown; but also treats the root cause, adjusts the skin of a patient, eliminates skin damp-heat, reduces the possibility of oil discharge and acne recurrence of the skin, and achieves the effect of treating both symptoms and root causes.
Detailed Description
The following description of the embodiments of the present invention will be made in detail, but not necessarily with reference to the specific embodiments of the present invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The methods described in the various embodiments of the present invention, unless otherwise specified, are all conventional. The materials, reagents and the like used, unless otherwise specified, are all commercially available.
Example 1
The oil-control acne-removing composition comprises the following components in parts by weight: 18 parts of loquat leaf, 9 parts of red sage root, 4 parts of pseudo-ginseng, 15 parts of astragalus root, 6 parts of magnolia officinalis, 3 parts of fructus cannabis, 5 parts of Chinese fevervine herb and 10 parts of rhizoma atractylodis.
The preparation method of the oil-control acne-removing composition specifically comprises the following steps:
Preparing a loquat leaf extract: pulverizing folium Eriobotryae into 60 mesh, decocting in water for 30min, filtering with 30 mesh filter paper, concentrating the filtrate, and removing solvent to obtain folium Eriobotryae extract; loquat leaf water = 1g:7ml.
Preparing rhizoma atractylodis extract: pulverizing rhizoma Atractylodis to 60 mesh, decocting in water for 30min, filtering with 30 mesh filter paper, concentrating the filtrate, and removing solvent to obtain rhizoma Atractylodis extract; rhizoma Atractylodis water=1g:7ml.
Preparing a red sage root extract: slicing Saviae Miltiorrhizae radix with a formula amount of 1mm, decocting with water for 1 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Saviae Miltiorrhizae radix is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1h, and filtering with 60-mesh filter paper to obtain secondary filtrate; mixing the first filtrate and the second filtrate, concentrating, and removing solvent to obtain Saviae Miltiorrhizae radix extract.
Preparing pseudo-ginseng extract: slicing Notoginseng radix with the formula amount and thickness of 1mm, decocting with water for 1 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Notoginseng radix is water=1g:10mL for the first time; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1h, and filtering with 60-mesh filter paper to obtain secondary filtrate; mixing the first filtrate and the second filtrate, concentrating, and removing solvent to obtain Notoginseng radix extract.
Preparing astragalus extract: slicing radix astragali with the formula amount and thickness of 1mm, adding water for decocting for 1h for the first time, and filtering with 60 mesh filter paper to obtain filter residue and first filtrate, wherein radix astragali is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1h, and filtering with 60-mesh filter paper to obtain secondary filtrate; combining the first filtrate and the second filtrate, concentrating, and removing solvent to obtain radix astragali extract.
Preparing magnolia bark extract: pulverizing cortex Magnolia officinalis to 30 mesh, adding 70% ethanol, refluxing at 75deg.C for 40min, centrifuging to obtain supernatant, concentrating, and removing solvent to obtain cortex Magnolia officinalis extract; the centrifugation conditions were: centrifuge at 5000rpm/min for 10min, magnolia officinalis 70% ethanol=1g:6mL.
Preparing fructus cannabis volatile oil: shelling fructus Cannabis according to formula amount, pulverizing to 80 mesh, soaking in 70% ethanol water solution for 4 hr, homogenizing, ultrasonic treating, filtering with 30 mesh filter paper, extracting with anhydrous ethanol for 2 times, mixing the extractive solutions, concentrating, and removing solvent to obtain fructus Cannabis volatile oil; wherein, the mass ratio of the hemp seed to the ethanol is 70 percent=1:2; the homogenization power was 185W and the rotational speed was 8000r/min. The ultrasonic power is 500W, the ultrasonic temperature is 50 ℃, and the ultrasonic time is 30min.
Preparing herba Paederiae volatile oil: pulverizing herba Paederiae to 80 mesh, soaking in 70% ethanol water solution for 12 hr, ultrasonic treating, filtering with 30 mesh filter paper, extracting with petroleum ether for 2 times, mixing extractive solutions, concentrating, and removing solvent to obtain herba Paederiae volatile oil; wherein the mass ratio of the Chinese fevervine herb to the 70% ethanol=1:4; the ultrasonic power is 400W, the ultrasonic temperature is 50 ℃, and the ultrasonic time is 45min.
Mixing the prepared loquat leaf extract, rhizoma atractylodis extract, red sage root extract, pseudo-ginseng extract, astragalus extract, magnolia bark extract, fructus cannabis volatile oil and paederia scandens volatile oil to obtain the oil-control acne-removing composition.
Example 2
The oil-control acne-removing composition comprises the following components in parts by weight: 22 parts of loquat leaf, 12 parts of red sage root, 6 parts of pseudo-ginseng, 18 parts of astragalus root, 8 parts of magnolia officinalis, 5 parts of fructus cannabis, 7 parts of Chinese fevervine herb and 12 parts of rhizoma atractylodis.
The preparation method of the oil-control acne-removing composition specifically comprises the following steps:
preparing a loquat leaf extract: pulverizing folium Eriobotryae into 60 mesh, decocting in water for 35min, filtering with 30 mesh filter paper, concentrating the filtrate, and removing solvent to obtain folium Eriobotryae extract; loquat leaf water = 1g:7ml.
Preparing rhizoma atractylodis extract: pulverizing rhizoma Atractylodis to 60 mesh, decocting in water for 35min, filtering, concentrating the filtrate, and removing solvent to obtain rhizoma Atractylodis extract; rhizoma Atractylodis water=1g:7ml.
Preparing a red sage root extract: slicing Saviae Miltiorrhizae radix with a formula amount of 1mm, decocting with water for 1 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Saviae Miltiorrhizae radix is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, decocting the filter residue for 1h with secondary water=1g:8ml, filtering with 60 mesh filter paper to obtain secondary filtrate, mixing the primary filtrate and the secondary filtrate, concentrating, and removing solvent to obtain Saviae Miltiorrhizae radix extract.
Preparing pseudo-ginseng extract: slicing Notoginseng radix with the formula amount and thickness of 1mm, decocting with water for 1 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Notoginseng radix is water=1g:10mL for the first time; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1h, and filtering with 60-mesh filter paper to obtain secondary filtrate; mixing the first filtrate and the second filtrate, concentrating, and removing solvent to obtain Notoginseng radix extract.
Preparing astragalus extract: slicing radix astragali with the formula amount and thickness of 1mm, adding water for decocting for 1h for the first time, and filtering with 60 mesh filter paper to obtain filter residue and first filtrate, wherein radix astragali is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1h, and filtering with 60-mesh filter paper to obtain secondary filtrate; combining the first filtrate and the second filtrate, concentrating, and removing solvent to obtain radix astragali extract.
Preparing magnolia bark extract: pulverizing cortex Magnolia officinalis to 30 mesh, adding 70% ethanol, refluxing at 75deg.C for 50min, centrifuging to obtain supernatant, concentrating, and removing solvent to obtain cortex Magnolia officinalis extract; the centrifugation conditions were: centrifugation at 6000rpm/min for 11min, magnolia officinalis 70% ethanol=1g:6mL.
Preparing fructus cannabis volatile oil: shelling fructus Cannabis according to formula amount, pulverizing to 80 mesh, soaking in 70% ethanol water solution for 4 hr, homogenizing, ultrasonic treating, filtering with 30 mesh filter paper, extracting with absolute ethanol for 2 times, mixing the extractive solutions, concentrating, and removing solvent to obtain fructus Cannabis volatile oil; wherein, the mass ratio of the hemp seed to the ethanol is 70 percent=1:2; the homogenization power was 185W and the rotational speed was 8000r/min. The ultrasonic power is 500W, the ultrasonic temperature is 50 ℃, and the ultrasonic time is 35min.
Preparing herba Paederiae volatile oil: pulverizing herba Paederiae to 80 mesh, soaking in 70% ethanol water solution for 15 hr, ultrasonic treating, filtering with 30 mesh filter paper, extracting with petroleum ether for 2 times, mixing extractive solutions, concentrating, and removing solvent to obtain herba Paederiae volatile oil; wherein the mass ratio of the Chinese fevervine herb to the 70% ethanol=1:4; the ultrasonic power is 400W, the ultrasonic temperature is 50 ℃, and the ultrasonic time is 50min.
Mixing the prepared loquat leaf extract, rhizoma atractylodis extract, red sage root extract, pseudo-ginseng extract, astragalus extract, magnolia bark extract, fructus cannabis volatile oil and paederia scandens volatile oil to obtain the oil-control acne-removing composition.
Example 3
The oil-control acne-removing composition comprises the following components in parts by weight: 25 parts of loquat leaf, 13 parts of red sage root, 8 parts of pseudo-ginseng, 21 parts of astragalus root, 9 parts of magnolia officinalis, 6 parts of fructus cannabis, 8 parts of Chinese fevervine herb and 13 parts of rhizoma atractylodis.
The preparation method of the oil-control acne-removing composition specifically comprises the following steps:
Preparing a loquat leaf extract: pulverizing folium Eriobotryae into 60 mesh, decocting in water for 40min, filtering with 30 mesh filter paper, concentrating the filtrate, and removing solvent to obtain folium Eriobotryae extract; loquat leaf water = 1g:7ml.
Preparing rhizoma atractylodis extract: pulverizing rhizoma Atractylodis to 60 mesh, decocting in water for 40min, filtering, concentrating the filtrate, and removing solvent to obtain rhizoma Atractylodis extract; rhizoma Atractylodis water=1g:7ml.
Preparing a red sage root extract: slicing Saviae Miltiorrhizae radix with a formula amount of 2mm, decocting with water for 1.5 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Saviae Miltiorrhizae radix is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, decocting the filter residue for 1.5h with secondary water=1g:8ml, filtering with 60 mesh filter paper to obtain secondary filtrate, mixing the primary filtrate and the secondary filtrate, concentrating, and removing solvent to obtain Saviae Miltiorrhizae radix extract.
Preparing pseudo-ginseng extract: slicing Notoginseng radix with the formula amount and thickness of 2mm, decocting with water for 1.5 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Notoginseng radix is water=1g:10mL for the first time; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1.5h, and filtering with 60-mesh filter paper to obtain secondary filtrate; mixing the first filtrate and the second filtrate, concentrating, and removing solvent to obtain Notoginseng radix extract.
Preparing astragalus extract: slicing radix astragali with the formula amount and thickness of 2mm, adding water for decocting for 1.5h for the first time, and filtering with 60 mesh filter paper to obtain filter residue and first filtrate, wherein radix astragali is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1.5h, and filtering with 60-mesh filter paper to obtain secondary filtrate; combining the first filtrate and the second filtrate, concentrating, and removing solvent to obtain radix astragali extract.
Preparing magnolia bark extract: pulverizing cortex Magnolia officinalis to 30 mesh, adding 70% ethanol, refluxing at 77 deg.C for 60min, centrifuging to obtain supernatant, concentrating, and removing solvent to obtain cortex Magnolia officinalis extract; the centrifugation conditions were: centrifugation at 7000rpm/min for 12min, magnolia officinalis 70% ethanol=1 g:6mL.
Preparing fructus cannabis volatile oil: shelling fructus Cannabis according to formula amount, pulverizing to 100 mesh, soaking in 70% ethanol water solution for 5 hr, homogenizing, ultrasonic treating, filtering with 30 mesh filter paper, extracting with absolute ethanol for 3 times, mixing the extractive solutions, concentrating, and removing solvent to obtain fructus Cannabis volatile oil; wherein, the mass ratio of the hemp seed to the ethanol is 70 percent=1:3; the homogenization power was 185W and the rotational speed was 9000r/min. The ultrasonic power is 500W, the ultrasonic temperature is 55 ℃, and the ultrasonic time is 40min.
Preparing herba Paederiae volatile oil: pulverizing herba Paederiae to 80 mesh, soaking in 70% ethanol water solution for 18 hr, ultrasonic treating, filtering with 30 mesh filter paper, extracting with petroleum ether for 3 times, mixing extractive solutions, concentrating, and removing solvent to obtain herba Paederiae volatile oil; wherein the mass ratio of the Chinese fevervine herb to the 70% ethanol=1:5; the ultrasonic power is 500W, the ultrasonic temperature is 55 ℃, and the ultrasonic time is 55min.
Mixing the prepared loquat leaf extract, rhizoma atractylodis extract, red sage root extract, pseudo-ginseng extract, astragalus extract, magnolia bark extract, fructus cannabis volatile oil and paederia scandens volatile oil to obtain the oil-control acne-removing composition.
Example 4
The oil-control acne-removing composition comprises the following components in parts by weight: 28 parts of loquat leaf, 14 parts of red sage root, 9 parts of pseudo-ginseng, 23 parts of astragalus root, 11 parts of magnolia officinalis, 7 parts of fructus cannabis, 9 parts of Chinese fevervine herb and 14 parts of rhizoma atractylodis.
The preparation method of the oil-control acne-removing composition specifically comprises the following steps:
Preparing a loquat leaf extract: pulverizing folium Eriobotryae into 80 mesh, decocting in water for 45min, filtering with 30 mesh filter paper, concentrating the filtrate, and removing solvent to obtain folium Eriobotryae extract; loquat leaf water = 1g:7ml.
Preparing rhizoma atractylodis extract: pulverizing rhizoma Atractylodis to 80 mesh, decocting in water for 45min, filtering, concentrating the filtrate, and removing solvent to obtain rhizoma Atractylodis extract; rhizoma Atractylodis water=1g:7ml.
Preparing a red sage root extract: slicing Saviae Miltiorrhizae radix with a formula amount of 3mm, decocting with water for 1.5 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Saviae Miltiorrhizae radix is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, decocting the filter residue for 1.5h with secondary water=1g:8ml, filtering with 60 mesh filter paper to obtain secondary filtrate, mixing the primary filtrate and the secondary filtrate, concentrating, and removing solvent to obtain Saviae Miltiorrhizae radix extract.
Preparing pseudo-ginseng extract: slicing Notoginseng radix with the formula amount and thickness of 3mm, decocting with water for 1.5 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Notoginseng radix is water=1g:10mL for the first time; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1.5h, and filtering with 60-mesh filter paper to obtain secondary filtrate; mixing the first filtrate and the second filtrate, concentrating, and removing solvent to obtain Notoginseng radix extract.
Preparing astragalus extract: slicing radix astragali with the formula amount and thickness of 3mm, adding water for decocting for 1.5h for the first time, and filtering with 60 mesh filter paper to obtain filter residue and first filtrate, wherein radix astragali is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1.5h, and filtering with 60-mesh filter paper to obtain secondary filtrate; combining the first filtrate and the second filtrate, concentrating, and removing solvent to obtain radix astragali extract.
Preparing magnolia bark extract: pulverizing cortex Magnolia officinalis to 30 mesh, adding 70% ethanol, refluxing at 78deg.C for 70min, centrifuging to obtain supernatant, concentrating, and removing solvent to obtain cortex Magnolia officinalis extract; the centrifugation conditions were: centrifuging at 8000rpm/min for 13min, and collecting cortex Magnolia officinalis with 70% ethanol=1g:6mL.
Preparing fructus cannabis volatile oil: shelling fructus Cannabis according to formula amount, pulverizing to 120 mesh, soaking in 70% ethanol water solution for 6 hr, homogenizing, ultrasonic treating, filtering with 30 mesh filter paper, extracting with absolute ethanol for 3 times, mixing the extractive solutions, concentrating, and removing solvent to obtain fructus Cannabis volatile oil; wherein, the mass ratio of the hemp seed to the ethanol is 70 percent=1:3; the homogenization power was 185W and the rotational speed was 10000r/min. The ultrasonic power is 500W, the ultrasonic temperature is 60 ℃, and the ultrasonic time is 45min.
Preparing herba Paederiae volatile oil: pulverizing herba Paederiae to 80 mesh, soaking in 70% ethanol water solution for 24 hr, ultrasonic treating, filtering with 30 mesh filter paper, extracting with petroleum ether for 3 times, mixing extractive solutions, concentrating, and removing solvent to obtain herba Paederiae volatile oil; wherein the mass ratio of the Chinese fevervine herb to the 70% ethanol=1:6; the ultrasonic power is 500W, the ultrasonic temperature is 60 ℃, and the ultrasonic time is 60min.
Mixing the prepared loquat leaf extract, rhizoma atractylodis extract, red sage root extract, pseudo-ginseng extract, astragalus extract, magnolia bark extract, fructus cannabis volatile oil and paederia scandens volatile oil to obtain the oil-control acne-removing composition.
Example 5
The oil-control acne-removing composition comprises the following components in parts by weight: 32 parts of loquat leaf, 17 parts of red sage root, 11 parts of pseudo-ginseng, 26 parts of astragalus root, 13 parts of magnolia officinalis, 9 parts of fructus cannabis, 12 parts of Chinese fevervine herb and 16 parts of rhizoma atractylodis.
The preparation method of the oil-control acne-removing composition specifically comprises the following steps:
Preparing a loquat leaf extract: pulverizing folium Eriobotryae into 80 mesh, decocting in water for 45min, filtering with 30 mesh filter paper, concentrating the filtrate, and removing solvent to obtain folium Eriobotryae extract; loquat leaf water = 1g:7ml.
Preparing rhizoma atractylodis extract: pulverizing rhizoma Atractylodis to 60 mesh, decocting in water for 45min, filtering, concentrating filtrate, and removing solvent to obtain rhizoma Atractylodis extract; rhizoma Atractylodis water=1g:7ml.
Preparing a red sage root extract: slicing Saviae Miltiorrhizae radix with a formula amount of 3mm, decocting with water for 1.5 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Saviae Miltiorrhizae radix is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, decocting the filter residue for 1.5h with secondary water=1g:8ml, filtering with 60 mesh filter paper to obtain secondary filtrate, mixing the primary filtrate and the secondary filtrate, concentrating, and removing solvent to obtain Saviae Miltiorrhizae radix extract.
Preparing pseudo-ginseng extract: slicing Notoginseng radix with the formula amount and thickness of 3mm, decocting with water for 1.5 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Notoginseng radix is water=1g:10mL for the first time; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1.5h, and filtering with 60-mesh filter paper to obtain secondary filtrate; mixing the first filtrate and the second filtrate, concentrating, and removing solvent to obtain Notoginseng radix extract.
Preparing astragalus extract: slicing radix astragali with the formula amount and thickness of 3mm, adding water for decocting for 1.5h for the first time, and filtering with 60 mesh filter paper to obtain filter residue and first filtrate, wherein radix astragali is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1.5h, and filtering with 60-mesh filter paper to obtain secondary filtrate; combining the first filtrate and the second filtrate, concentrating, and removing solvent to obtain radix astragali extract.
Preparing magnolia bark extract: pulverizing cortex Magnolia officinalis to 30 mesh, adding 70% ethanol, refluxing at 80deg.C for 70min, centrifuging to obtain supernatant, concentrating, and removing solvent to obtain cortex Magnolia officinalis extract; the centrifugation conditions were: centrifuging at 8000rpm/min for 15min, and collecting cortex Magnolia officinalis with 70% ethanol=1g:6mL.
Preparing fructus cannabis volatile oil: shelling fructus Cannabis according to formula amount, pulverizing to 120 mesh, soaking in 70% ethanol water solution for 6 hr, homogenizing, ultrasonic treating, filtering with 30 mesh filter paper, extracting with absolute ethanol for 3 times, mixing the extractive solutions, concentrating, and removing solvent to obtain fructus Cannabis volatile oil; wherein, the mass ratio of the hemp seed to the ethanol is 70 percent=1:3; the homogenization power was 185W and the rotational speed was 10000r/min. The ultrasonic power is 500W, the ultrasonic temperature is 60 ℃, and the ultrasonic time is 45min.
Preparing herba Paederiae volatile oil: pulverizing herba Paederiae to 80 mesh, soaking in 70% ethanol water solution for 24 hr, ultrasonic treating, filtering with 30 mesh filter paper, extracting with petroleum ether for 3 times, mixing extractive solutions, concentrating, and removing solvent to obtain herba Paederiae volatile oil; wherein the mass ratio of the Chinese fevervine herb to the 70% ethanol=1:6; the ultrasonic power is 500W, the ultrasonic temperature is 60 ℃, and the ultrasonic time is 60min.
Mixing the prepared loquat leaf extract, rhizoma atractylodis extract, red sage root extract, pseudo-ginseng extract, astragalus extract, magnolia bark extract, fructus cannabis volatile oil and paederia scandens volatile oil to obtain the oil-control acne-removing composition.
Comparative example 1
The oil-control acne-removing composition comprises the following components in parts by weight: 15 parts of astragalus, 6 parts of magnolia officinalis, 3 parts of fructus cannabis, 5 parts of Chinese fevervine herb and 10 parts of rhizoma atractylodis.
The preparation method of the oil-control acne-removing composition specifically comprises the following steps:
Preparing rhizoma atractylodis extract: pulverizing rhizoma Atractylodis to 60 mesh, decocting in water for 30min, filtering with 30 mesh filter paper, concentrating the filtrate, and removing solvent to obtain rhizoma Atractylodis extract; rhizoma Atractylodis water=1g:7ml.
Preparing astragalus extract: slicing radix astragali with the formula amount and thickness of 1mm, adding water for decocting for 1h for the first time, and filtering with 60 mesh filter paper to obtain filter residue and first filtrate, wherein radix astragali is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, decocting the filter residue for 1h with secondary water=1g:8ml, filtering with 60 mesh filter paper to obtain secondary filtrate, mixing the primary filtrate and the secondary filtrate, concentrating, and removing solvent to obtain radix astragali extract.
Preparing magnolia bark extract: pulverizing cortex Magnolia officinalis to 30 mesh, adding 70% ethanol, refluxing at 75deg.C for 40min, centrifuging to obtain supernatant, concentrating, and removing solvent to obtain cortex Magnolia officinalis extract; the centrifugation conditions were: centrifuge at 5000rpm/min for 10min.
Preparing fructus cannabis volatile oil: shelling fructus Cannabis according to formula amount, pulverizing to 80 mesh, soaking in 70% ethanol water solution for 4 hr, homogenizing, ultrasonic treating, filtering with 30 mesh filter paper, extracting with absolute ethanol for 2 times, mixing the extractive solutions, concentrating, and removing solvent to obtain fructus Cannabis volatile oil; wherein, the mass ratio of the hemp seed to the ethanol is 70 percent=1:2; the homogenization power was 185W and the rotational speed was 8000r/min. The ultrasonic power is 500W, the ultrasonic temperature is 50 ℃, and the ultrasonic time is 30min.
Preparing herba Paederiae volatile oil: pulverizing herba Paederiae to 80 mesh, soaking in 70% ethanol water solution for 12 hr, ultrasonic treating, filtering with 30 mesh filter paper, extracting with petroleum ether for 2 times, mixing extractive solutions, concentrating, and removing solvent to obtain herba Paederiae volatile oil; wherein the mass ratio of the Chinese fevervine herb to the 70% ethanol=1:4; the ultrasonic power is 400W, the temperature is 50 ℃, and the time is 45min.
Mixing the prepared rhizoma Atractylodis extract, radix astragali extract, cortex Magnolia officinalis extract, fructus Cannabis volatile oil and herba Paederiae volatile oil to obtain the oil-controlling acne-removing composition.
Comparative example 2
The oil-control acne-removing composition comprises the following components in parts by weight: 18 parts of loquat leaf, 9 parts of red sage root, 4 parts of pseudo-ginseng, 6 parts of magnolia bark and 10 parts of rhizoma atractylodis.
The preparation method of the oil-control acne-removing composition specifically comprises the following steps:
Preparing a loquat leaf extract: pulverizing folium Eriobotryae into 60 mesh, decocting in water for 30min, filtering with 30 mesh filter paper, concentrating the filtrate, and removing solvent to obtain folium Eriobotryae extract; loquat leaf water = 1g:7ml.
Preparing rhizoma atractylodis extract: pulverizing rhizoma Atractylodis to 60 mesh, decocting in water for 30min, filtering, concentrating the filtrate, and removing solvent to obtain rhizoma Atractylodis extract; rhizoma Atractylodis water=1g:7ml.
Preparing a red sage root extract: slicing Saviae Miltiorrhizae radix with a formula amount of 1mm, decocting with water for 1 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Saviae Miltiorrhizae radix is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, decocting Saviae Miltiorrhizae radix with secondary water=1g:8ml, filtering with 60 mesh filter paper to obtain secondary filtrate, mixing the primary filtrate and secondary filtrate, concentrating, and removing solvent to obtain Saviae Miltiorrhizae radix extract.
Preparing pseudo-ginseng extract: slicing Notoginseng radix with the formula amount and thickness of 1mm, decocting with water for 1 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Notoginseng radix is water=1g:10mL for the first time; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1h, and filtering with 60-mesh filter paper to obtain secondary filtrate; mixing the first filtrate and the second filtrate, concentrating, and removing solvent to obtain Notoginseng radix extract.
Preparing astragalus extract: slicing radix astragali with the formula amount and thickness of 1mm, adding water for decocting for 1h for the first time, and filtering with 60 mesh filter paper to obtain filter residue and first filtrate, wherein radix astragali is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1h, and filtering with 60-mesh filter paper to obtain secondary filtrate; combining the first filtrate and the second filtrate, concentrating, and removing solvent to obtain radix astragali extract.
Preparing magnolia bark extract: pulverizing cortex Magnolia officinalis to 30 mesh, adding 70% ethanol, refluxing at 75deg.C for 40min, centrifuging to obtain supernatant, concentrating, and removing solvent to obtain cortex Magnolia officinalis extract; the centrifugation conditions were: centrifuge at 5000rpm/min for 10min, magnolia officinalis 70% ethanol=1g:6mL.
Mixing the prepared loquat leaf extract, rhizoma atractylodis extract, red sage root extract and pseudo-ginseng extract and magnolia officinalis extract to obtain the oil-control acne-removing composition.
Comparative example 3
The oil-control acne-removing composition comprises the following components in parts by weight: 18 parts of loquat leaf, 9 parts of red sage root, 4 parts of pseudo-ginseng, 15 parts of astragalus, 3 parts of fructus cannabis and 5 parts of Chinese fevervine herb.
The preparation method of the oil-control acne-removing composition specifically comprises the following steps:
Preparing a loquat leaf extract: pulverizing folium Eriobotryae into 60 mesh, decocting in water for 30min, filtering with 30 mesh filter paper, concentrating the filtrate, and removing solvent to obtain folium Eriobotryae extract; loquat leaf water = 1g:7ml.
Preparing a red sage root extract: slicing Saviae Miltiorrhizae radix with a formula amount of 1mm, decocting with water for 1 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Saviae Miltiorrhizae radix is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, decocting the filter residue for 1h with secondary water=1g:8ml, filtering with 60 mesh filter paper to obtain secondary filtrate, mixing the primary filtrate and the secondary filtrate, concentrating, and removing solvent to obtain Saviae Miltiorrhizae radix extract.
Preparing pseudo-ginseng extract: slicing Notoginseng radix with the formula amount and thickness of 1mm, decocting with water for 1 hr, and filtering with 60 mesh filter paper to obtain residue and first filtrate, wherein Notoginseng radix is water=1g:10mL for the first time; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1h, and filtering with 60-mesh filter paper to obtain secondary filtrate; mixing the first filtrate and the second filtrate, concentrating, and removing solvent to obtain Notoginseng radix extract.
Preparing astragalus extract: slicing radix astragali with the formula amount and thickness of 1mm, adding water for decocting for 1h for the first time, and filtering with 60 mesh filter paper to obtain filter residue and first filtrate, wherein radix astragali is water for the first time=1g:10mL; adding secondary water into the filter residue for secondary water extraction, wherein the filter residue is obtained by decocting the secondary water=1g:8ml for 1h, and filtering with 60-mesh filter paper to obtain secondary filtrate; combining the first filtrate and the second filtrate, concentrating, and removing solvent to obtain radix astragali extract.
Preparing fructus cannabis volatile oil: shelling fructus Cannabis according to formula amount, pulverizing to 80 mesh, soaking in 70% ethanol water solution for 4 hr, homogenizing, ultrasonic treating, filtering with 30 mesh filter paper, extracting with absolute ethanol for 2 times, mixing the extractive solutions, concentrating, and removing solvent to obtain fructus Cannabis volatile oil; wherein, the mass ratio of the hemp seed to the ethanol is 70 percent=1:2; the homogenization power was 185W and the rotational speed was 8000r/min. The ultrasonic power is 500W, the ultrasonic temperature is 50 ℃, and the ultrasonic time is 30min.
Preparing herba Paederiae volatile oil: pulverizing herba Paederiae to 80 mesh, soaking in 70% ethanol water solution for 12 hr, ultrasonic treating, filtering with 30 mesh filter paper, extracting with petroleum ether for 2 times, mixing extractive solutions, concentrating, and removing solvent to obtain herba Paederiae volatile oil; wherein the mass ratio of the Chinese fevervine herb to the 70% ethanol=1:4; the ultrasonic power is 400W, the ultrasonic temperature is 50 ℃, and the ultrasonic time is 45min.
Mixing the prepared loquat leaf extract, the red sage extract, the pseudo-ginseng extract, the astragalus extract, the hemp seed volatile oil and the paederia scandens volatile oil to obtain the oil-control acne-removing composition.
Acne removal capability test
The oil-control acne-removing composition prepared in the embodiment 5 of the invention can be prepared into an oil-control acne-removing face cream, an oil-control acne-removing mask and an oil-control acne-removing water according to requirements, wherein the acne-removing capability of the oil-control acne-removing face cream and the oil-control acne-removing water is basically consistent with that of the oil-control acne-removing mask, and the following test is taken as an example of the oil-control acne-removing mask.
Preparing an oil-control acne-removing mask: the oil-control acne-removing composition prepared in the embodiment and the comparative example is respectively taken, uniformly mixed with honey and blended into paste, and the oil-control acne-removing mask is obtained; wherein the raw materials comprise the following components in parts by weight: 10 parts of oil control acne removal composition and 10 parts of honey.
320 Subjects are selected, the ages of the subjects are 15-30 years, the subjects are randomly divided into 8 groups, 40 persons in each group are applied to affected parts for 15-20 min after face washing at night, the oil-control acne-removing facial masks prepared by the oil-control acne-removing compositions prepared in examples 1-5 and comparative examples 1-3 are respectively used, then the affected parts are cleaned, skin care is carried out, and after continuous use for 3 months, the statistical effect is achieved.
Criterion for judging oil-control acne-removing effect
Remarkably effective means: the redness and the exudation obviously subside, and the number of the abscess, the nodule and the papular acne is reduced by more than half;
the effective means that: the redness and the exudation partially subside, and the number of abscess, nodules and papular acnes is reduced;
Invalidation refers to: the symptoms were not improved.
Recurrence: and also has abscess, nodule, papular acne.
Table 1 oil control and acne treatment effects of different examples and comparative examples
As can be seen from table 1, in comparative example 1, no monarch drug was added, and compared with comparative example 1, the total effective rate of the oil-controlling acne-removing mask prepared in examples 1 to 5 has obvious advantages, which indicates that monarch drug plays a decisive role in controlling oil and removing acne. Compared with comparative example 2, the oil-control acne-removing mask prepared in examples 1 to 5 has a larger total effective rate advantage, and shows that the monarch drug can achieve a better effect only by matching with the ministerial drug. The total effective rate of the oil-control acne-removing mask prepared in examples 1 to 5 is also advantageous compared with comparative example 3 without adjuvant, which shows that the adjuvant plays a certain role in the composition. From the aspect of recurrence rate, after the oil-control acne-removing mask prepared in examples 1-5 is used, the recurrence rate of the acne of a patient is far lower than that of the oil-control acne-removing mask prepared in comparative examples 1-3, which shows that the oil-control acne-removing mask prepared in the invention can not only remove the acne which is already grown, but also can internally regulate the skin balance of the patient, prevent the acne from regenerating, and achieve the effect of treating both symptoms and root causes. In conclusion, the oil-control acne-removing composition prepared by the invention can achieve the best effect only by the mutual cooperation of monarch, minister, assistant and guide and the synergistic effect, and is indispensable.
While preferred embodiments of the present invention have been described, additional variations and modifications in those embodiments may occur to those skilled in the art once they learn of the basic inventive concepts. It is therefore intended that the following claims be interpreted as including the preferred embodiments and all such alterations and modifications as fall within the scope of the invention.
It will be apparent to those skilled in the art that various modifications and variations can be made to the present invention without departing from the spirit or scope of the invention. Thus, it is intended that the present invention also include such modifications and alterations insofar as they come within the scope of the appended claims or the equivalents thereof.
Claims (10)
1. The oil-control acne-removing composition is characterized by comprising the following components in parts by weight: 18-32 parts of loquat leaf, 9-17 parts of red sage root, 4-11 parts of pseudo-ginseng, 15-26 parts of astragalus root, 6-13 parts of magnolia bark, 3-9 parts of fructus cannabis, 5-12 parts of Chinese fevervine herb and 10-16 parts of rhizoma atractylodis.
2. The oil control acne removal composition according to claim 1, wherein the composition comprises the following raw materials in parts by weight: 22-28 parts of loquat leaf, 12-14 parts of red sage root, 6-9 parts of pseudo-ginseng, 18-23 parts of astragalus root, 8-11 parts of magnolia officinalis, 5-7 parts of fructus cannabis, 7-9 parts of Chinese fevervine herb and 12-14 parts of rhizoma atractylodis.
3. The oil control acne removal composition according to claim 2, wherein the composition comprises the following components in parts by weight: 25 parts of loquat leaf, 13 parts of red sage root, 8 parts of pseudo-ginseng, 21 parts of astragalus root, 9 parts of magnolia officinalis, 6 parts of fructus cannabis, 8 parts of Chinese fevervine herb and 13 parts of rhizoma atractylodis.
4. A method for preparing the oil-control acne-removing composition according to any one of claims 1 to 3, which is characterized by comprising the following steps:
Preparing a loquat leaf extract: pulverizing folium Eriobotryae according to the formula amount, decocting in water for 30-45 min, filtering, and concentrating the filtrate to obtain folium Eriobotryae extract; the preparation method of the rhizoma atractylodis extract is the same as that of the loquat leaf extract;
preparing a red sage root extract: slicing the red sage root with the formula amount, adding water for decoction for 1-1.5 h, filtering and concentrating to obtain the red sage root extract;
The preparation methods of the pseudo-ginseng extract and the astragalus extract are the same as the preparation method of the red sage root extract;
preparing magnolia bark extract: pulverizing cortex Magnolia officinalis, adding 70% ethanol, refluxing at 75-80deg.C for 40-70 min, centrifuging to obtain supernatant, and concentrating to obtain cortex Magnolia officinalis extract;
Preparing fructus cannabis volatile oil: shelling fructus Cannabis according to the formula amount, pulverizing to 80-120 meshes, soaking in 70% ethanol water solution for 4-6 h, homogenizing, ultrasonic treating, filtering, extracting, and concentrating to obtain fructus Cannabis volatile oil; wherein the mass ratio of the hemp seed to the ethanol is 70 percent=1:2-3;
Preparing herba Paederiae volatile oil: pulverizing herba Paederiae, soaking in 70% ethanol water solution for 12-24 hr, ultrasonic treating, filtering, and extracting to obtain herba Paederiae volatile oil; wherein the mass ratio of the Chinese fevervine herb to the 70% ethanol=1:4-6;
Mixing the prepared loquat leaf extract, rhizoma atractylodis extract, red sage root extract, pseudo-ginseng extract, astragalus extract, magnolia bark extract, fructus cannabis volatile oil and paederia scandens volatile oil to obtain the oil-control acne-removing composition.
5. The method for preparing the oil-control acne-removing composition according to claim 4, wherein the loquat leaf is water=1g:7ml.
6. The method for preparing the oil-controlling and acne-removing composition according to claim 4, wherein when preparing the magnolia bark extract, the centrifugation conditions are as follows: centrifuging at 5000-8000 rpm/min for 10-15 min.
7. The method for preparing an oil-controlling and acne-removing composition according to claim 4, wherein the homogenizing power is 185W and the rotating speed is 8000-10000 r/min when the hemp seed volatile oil is prepared.
8. The method for preparing the oil-controlling and acne-removing composition according to claim 7, wherein the ultrasonic power is 500W, the temperature is 50-60 ℃ and the time is 30-45 min when the hemp seed volatile oil is prepared.
9. The oil-controlling and acne-removing composition according to claim 1, which is used for preparing skin care products.
10. The use of the oil-control acne-removing composition according to claim 9, wherein the skin care product comprises an oil-control acne-removing face cream, an oil-control acne-removing face mask and an oil-control acne-removing water.
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