CN118121522A - Hair-loss-preventing and hair-nourishing shampoo composition, and preparation method and application thereof - Google Patents
Hair-loss-preventing and hair-nourishing shampoo composition, and preparation method and application thereof Download PDFInfo
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- CN118121522A CN118121522A CN202410547004.5A CN202410547004A CN118121522A CN 118121522 A CN118121522 A CN 118121522A CN 202410547004 A CN202410547004 A CN 202410547004A CN 118121522 A CN118121522 A CN 118121522A
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- hair
- extract
- shampoo composition
- sodium
- mixture
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- 239000002453 shampoo Substances 0.000 title claims abstract description 50
- 238000002360 preparation method Methods 0.000 title claims abstract description 26
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- 208000024963 hair loss Diseases 0.000 title claims description 13
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 26
- 230000003656 anti-hair-loss Effects 0.000 claims abstract description 22
- MRUAUOIMASANKQ-UHFFFAOYSA-O carboxymethyl-[3-(dodecanoylamino)propyl]-dimethylazanium Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(O)=O MRUAUOIMASANKQ-UHFFFAOYSA-O 0.000 claims abstract description 17
- 229940075468 lauramidopropyl betaine Drugs 0.000 claims abstract description 17
- 239000002738 chelating agent Substances 0.000 claims abstract description 16
- 239000000419 plant extract Substances 0.000 claims abstract description 15
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 10
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 8
- 150000001336 alkenes Chemical class 0.000 claims abstract description 8
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 8
- 239000011734 sodium Substances 0.000 claims abstract description 8
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims abstract description 8
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- 125000003118 aryl group Chemical group 0.000 claims abstract description 3
- 239000000284 extract Substances 0.000 claims description 36
- 229940079776 sodium cocoyl isethionate Drugs 0.000 claims description 13
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- IWIUXJGIDSGWDN-UQKRIMTDSA-M sodium;(2s)-2-(dodecanoylamino)pentanedioate;hydron Chemical compound [Na+].CCCCCCCCCCCC(=O)N[C@H](C([O-])=O)CCC(O)=O IWIUXJGIDSGWDN-UQKRIMTDSA-M 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 7
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- 239000002994 raw material Substances 0.000 claims description 5
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims description 4
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Landscapes
- Cosmetics (AREA)
Abstract
The invention provides an anti-hair loss hair-nourishing shampoo composition, and a preparation method and application thereof, and belongs to the technical field of cosmetics. The composition comprises the following components in percentage by weight: 4-6% of plant extract, 35-50% of surfactant, 0.1-0.5% of conditioner, 0.2-0.6% of antidandruff agent, 0.05-0.2% of chelating agent, 0.6-1.0% of preservative, 0.3-0.8% of aromatic, 0.1-0.3% of pH regulator, 0.05-0.15% of water-oil balancing agent and the balance of water; the invention uses the mixture of lauramidopropyl betaine, C14-16 alkene sodium sulfonate, cocoyl isethionate sodium, cocoyl glycine potassium and lauroyl sodium glutamate as the surfactant, and can enable the scalp to absorb the nutrition components in the plant extract better, thereby solving the problem of poor absorption effect of the plant extract.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to an anti-hair-loss hair-growing shampoo composition, and a preparation method and application thereof.
Background
Currently, in the cosmetic category, hair loss preventing and hair growing products are generally classified into two categories: a Chinese medicinal formulation, the common ingredient is ginger, polygonum multiflorum, cacumen biotae, radix sophorae flavescentis, etc., these components have better effects of preventing alopecia and promoting hair growth, but because the absorption effect is general in the use, therefore the improvement effect on alopecia is not ideal; the other is a compound with definite efficacy, such as pyrrolidinyl diaminopyrimidine oxide, which has certain pertinence and can generate dependence after long-term use.
Chinese patent CN101890080B discloses an anti-hair-growing medicinal composition and a preparation method thereof, and a shampoo containing the medicinal composition and a preparation method thereof, wherein the anti-hair-growing medicinal composition comprises 1-4 parts by weight of ginseng, 5-9 parts by weight of radix sophorae flavescentis, 5-9 parts by weight of polygonum multiflorum, 3-6 parts by weight of ligusticum wallichii and 2-6 parts by weight of snakehead intestines. However, the hair-loss preventing and hair-growing effects of the composition cannot better meet the requirements.
Chinese patent CN114392263B discloses a glycyrrhizin anti-hair loss and hair care composition and a preparation method thereof, which is prepared from glycyrrhizin, shikonin, PEG-60 hydrogenated castor oil, 1, 2-hexanediol, p-hydroxyacetophenone, ethylhexyl glycerol, green tea essence and deionized water. The prepared glycyrrhizin anti-hair loss composition has good efficacy through the synergistic effect of the glycyrrhizin and the shikonin, has the efficacy of repairing hair follicles and maintaining scalp besides anti-hair loss, and has high product safety and less side effect. The preparation method is simple, does not need complex instruments and equipment, has lower preparation cost and is easy to popularize. However, the hair-growing and anti-inflammatory effects of the composition of the invention do not meet the requirements better.
Chinese patent CN113908091B discloses an anti-hair loss hair-growing composition, and its preparation method and application. The hair-loss preventing hair-growing composition mainly comprises the following components: glycyrrhizin, boerduo leaf extract, oleanolic acid and stilbene glucoside. The four components cooperate and synergistically, so that the activity of 5 alpha-reductase is effectively inhibited, the conversion of testosterone into DHT by 5 alpha-reductase is avoided to a great extent, and the problems of rapid entry into the retrograde phase, micromation, hair loss and the like caused by the action of high-activity DHT on hair follicles after the combination of the high-activity DHT and an androgen receptor are avoided; meanwhile, the anti-hair loss and hair growth composition can also inhibit the expression of IL-1 beta and TNF-alpha inflammatory factors in skin hair follicles, so that the purposes of preventing hair loss and promoting hair growth are finally achieved, but the application does not study the antibacterial performance of the composition.
Therefore, there is a need to develop a shampoo composition which can effectively inhibit bacteria and resist inflammation and has the effects of preventing alopecia and nourishing hair and a preparation method thereof.
Disclosure of Invention
Based on the defects existing in the prior art, the invention aims to provide the shampoo composition containing various plant components, which has the advantages of good absorption effect, high safety, effective bacteriostasis, anti-inflammatory and hair-nourishing effects and a preparation method thereof.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
An anti-drop hair-care shampoo composition comprises the following components in percentage by weight: 4-6% of plant extract, 35-50% of surfactant, 0.1-0.5% of conditioner, 0.2-0.6% of anti-dandruff agent, 0.05-0.2% of chelating agent, 0.6-1.0% of preservative, 0.3-0.8% of aromatic, 0.1-0.3% of pH regulator, 0.05-0.15% of water-oil balancing agent and the balance of water.
The plant extract is a mixture of rice chaff extract, ginger root extract, ginseng root extract, kelp extract, pomelo seed extract, centella asiatica extract and biota orientalis extract;
preferably, the mass ratio of the rice chaff extract, the ginger root extract, the ginseng root extract, the kelp extract, the pomelo seed extract and the centella asiatica extract is 5:5:5:3.8:1.2.
The surfactant is one or more selected from lauramidopropyl betaine, sodium C14-16 olefin sulfonate, sodium cocoyl isethionate, potassium cocoyl glycinate and sodium lauroyl glutamate;
Preferably, the surfactant is a mixture of lauramidopropyl betaine, sodium C14-16 olefin sulfonate, sodium cocoyl isethionate, potassium cocoyl glycinate, and sodium lauroyl glutamate.
Preferably, the mass ratio of the lauramidopropyl betaine, the sodium C14-16 olefin sulfonate, the sodium cocoyl isethionate, the potassium cocoyl glycinate and the sodium lauroyl glutamate is 15-20:12-15:2-9:1.2-2.4:0.6-1.5;
still preferably, the mass ratio of the lauramidopropyl betaine, the sodium C14-16 olefin sulfonate, the sodium cocoyl isethionate, the potassium cocoyl glycinate and the sodium lauroyl glutamate is 20:13:2:2:1.
The application takes the mixture of rice chaff extract, ginger root extract, ginseng root extract, kelp extract, pomelo seed extract, centella asiatica extract and arborvitae twig extract as plant extract components, has better hair loss prevention effect, and the hair loss prevention effect of the shampoo composition can be obviously improved by mixing the components, and has higher repairing effect on scalp hair sacs; in addition, the application uses the mixture of lauramidopropyl betaine, C14-16 alkene sodium sulfonate, cocoyl isethionate sodium, cocoyl glycine potassium and lauroyl sodium glutamate as the surfactant, so that the scalp can absorb the nutrition components in the plant extract better, thereby improving the problem of poor absorption effect of the plant extract.
The conditioner is polyquaternium-10.
The anti-dandruff agent is piroctone olamine salt.
The chelating agent is hydroxyethyldiphosphate.
The preservative is a mixture of phenoxyethanol, octylglycol and ethylhexyl glycerol, and the mass ratio is 8:1:1.
The pH regulator is citric acid.
The water-oil balancing agent is a mixture of gum arabic and salicylic acid.
The mass ratio of the conditioner to the chelating agent to the water-oil balancing agent is 1-5:0.5-2:0.5-1.5; preferably, the mass ratio of the conditioning agent, the chelating agent and the water-oil balancing agent is 3:1:1.
The invention surprisingly discovers that controlling the mass ratio of the conditioning agent, the chelating agent and the water-oil balancing agent in the implementation process can lead the composition to have better antibacterial stability and long-term antibacterial effect, can obviously reduce the secretion of grease, but has better moisture retention.
The hair-loss preventing and hair-growing shampoo composition also comprises a bacteriostatic agent, and 1-2% of biota orientalis extract in parts by weight.
The invention also provides a preparation method of the anti-hair loss and hair-growing shampoo composition, which comprises the following steps:
(1) Adding lauramidopropyl betaine and C14-16 sodium olefin sulfonate into a stirring pot, homogenizing for 3 minutes, heating and stirring until the mixture is completely dissolved to obtain a mixture 1;
(2) Adding sodium cocoyl isethionate and polyquaternium-10 into the mixture 1, and keeping the temperature for 15 minutes to obtain a mixture 2;
(3) And cooling the mixture 2 to 45 ℃, adding the rest raw materials, and uniformly mixing to obtain the anti-hair loss hair-growing shampoo composition.
The invention also provides application of the anti-hair loss and hair-nourishing shampoo composition in preparing shampoo products.
The shampoo products include, but are not limited to, shampoos, conditioners, shampoos, hair treatment creams.
Compared with the prior art, the invention has the beneficial effects that:
(1) The application takes the mixture of rice chaff extract, ginger root extract, ginseng root extract, kelp extract, pomelo seed extract, centella asiatica extract and arborvitae twig extract as plant extract components, has better hair loss prevention effect, and the hair loss prevention effect of the shampoo composition can be obviously improved by mixing the components, and has higher repairing effect on scalp hair sacs; in addition, the application uses the mixture of lauramidopropyl betaine, C14-16 alkene sodium sulfonate, cocoyl isethionate sodium, cocoyl glycine potassium and lauroyl sodium glutamate as the surfactant, so that the scalp can absorb the nutrition components in the plant extract better, thereby improving the problem of poor absorption effect of the plant extract.
(2) The invention surprisingly discovers that controlling the mass ratio of the conditioning agent, the chelating agent and the water-oil balancing agent in the implementation process can lead the composition to have better antibacterial stability and long-term antibacterial effect, can obviously reduce the secretion of grease, but has better moisture retention.
(3) The invention uses the synergistic cooperation of the plant extract and the surfactant to ensure that the composition has good anti-inflammatory effect and has good repairing and relieving effects on scalp hair follicles, thereby achieving the effect of preventing alopecia.
Detailed Description
Hereinafter, specific embodiments of the present invention will be described. However, the present invention is not limited to the above description, and various changes, modifications, and improvements may be made according to knowledge of the manufacturer without departing from the scope of the present invention.
The manufacturers and models of the components in the following examples are:
Example 1A hair-loss preventing and hair-growing shampoo composition and its preparation method
The composition comprises the following components in percentage by weight:
the preparation method comprises the following steps: the method comprises the following steps:
(1) Adding lauramidopropyl betaine and C14-16 sodium olefin sulfonate into a stirring pot, homogenizing for 3 minutes, heating and stirring until the mixture is completely dissolved to obtain a mixture 1;
(2) Adding sodium cocoyl isethionate and polyquaternium-10 into the mixture 1, and keeping the temperature for 15 minutes to obtain a mixture 2;
(3) And cooling the mixture 2 to 45 ℃, adding the rest raw materials, and uniformly mixing to obtain the anti-hair loss hair-growing shampoo composition.
Example 2A hair-loss preventing and hair-growing shampoo composition and its preparation method
The composition comprises the following components in percentage by weight:
the preparation method comprises the following steps: the method comprises the following steps:
(1) Adding lauramidopropyl betaine and C14-16 sodium olefin sulfonate into a stirring pot, homogenizing for 3 minutes, heating and stirring until the mixture is completely dissolved to obtain a mixture 1;
(2) Adding sodium cocoyl isethionate and polyquaternium-10 into the mixture 1, and keeping the temperature for 15 minutes to obtain a mixture 2;
(3) And cooling the mixture 2 to 45 ℃, adding the rest raw materials, and uniformly mixing to obtain the anti-hair loss hair-growing shampoo composition.
Example 3A hair-loss preventing and hair-growing shampoo composition and its preparation method
The composition comprises the following components in percentage by weight:
the preparation method comprises the following steps: the method comprises the following steps:
(1) Adding lauramidopropyl betaine and C14-16 sodium olefin sulfonate into a stirring pot, homogenizing for 3 minutes, heating and stirring until the mixture is completely dissolved to obtain a mixture 1;
(2) Adding sodium cocoyl isethionate and polyquaternium-10 into the mixture 1, and keeping the temperature for 15 minutes to obtain a mixture 2;
(3) And cooling the mixture 2 to 45 ℃, adding the rest raw materials, and uniformly mixing to obtain the anti-hair loss hair-growing shampoo composition.
Comparative example 1
The difference from example 1 is that: omitting the leaf extract of Platycladus ORIENTALIS (THUJA ORIENTALIS) and increasing the content of the plant extract, namely:
the preparation method is the same as in example 1.
Comparative example 2
The difference from example 1 is that: omitting lauramidopropyl betaine, namely:
the preparation method is the same as in example 1.
Comparative example 3
The difference from example 1 is that: the mass ratio of lauramidopropyl betaine, sodium C14-16 olefin sulfonate, sodium cocoyl isethionate, potassium cocoyl glycinate and sodium lauroyl glutamate is 2:2:4:1:1, namely:
The content of each of the other components and the preparation method were the same as in example 1.
Comparative example 4
The difference from example 1 is that: the mass ratio of the conditioning agent to the chelating agent to the water-oil balancing agent is 1:1:8, namely:
The content of each of the other components and the preparation method were the same as in example 1.
Comparative example 5
The difference from example 1 is that: the mass ratio of the conditioning agent to the chelating agent to the water-oil balancing agent is 0.5:9:0.5, namely:
The content of each of the other components and the preparation method were the same as in example 1.
Effect data
1. Bacteriostasis test
The oxford cup method is adopted to measure the bacteriostasis capability of two common bacteria of malassezia and staphylococcus aureus, and the experimental result judgment standard is as follows: the diameter of the inhibition zone is less than or equal to 10mm, which indicates that the inhibition effect is not obvious, the diameter of the inhibition zone is 10mm-15mm, which indicates moderate inhibition, and the diameter of the inhibition zone is more than or equal to 15mm, which indicates high inhibition, and the experimental results are shown in table 1.
TABLE 1
As can be seen from the detection results of table 1, the shampoo compositions prepared in examples 1-3 have good antibacterial performance, and show high antibacterial performance to malassezia and staphylococcus aureus, while omitting the cacumen biotae extract in comparative example 1 has obviously reduced antibacterial performance, which indicates that cacumen biotae can obviously influence the antibacterial performance of the product; comparative examples 2-3 the change of the kind or the ratio of the surfactant has little influence on the bacteriostasis performance; comparative examples 4-5 the change in the mass ratio of conditioner, chelating agent and water-oil balancing agent, when outside the scope of the present application, affects the absorption of the scalp to the ingredients in the shampoo composition to some extent, and thus affects the bacteriostatic properties, that is, only the shampoo composition protected by the present application has a good bacteriostatic property.
2. Antibacterial stability
The test method comprises the following steps: plate contact method
The operation method comprises the following steps: removing hair and fat meat from pigskin, cutting into square pieces of 4cm×4cm, and sterilizing by Co 60 -gamma ray irradiation.
1. Weighing 44.0g of Leemming-Notman culture medium foundation in 1L of deionized water, boiling until the solution is completely dissolved, adding 1.6mL of olive oil into each 80mL of the solution, cooling the solution to about 50 ℃ after autoclaving, adding 40mg of cycloheximide solution into each 80mL of the solution under aseptic operation, and preparing LN flat plates (90 mm multiplied by 15 mm) for later use. 100 mu L of 1X 10 5-3×105 CFU/mL of malassezia suspension are respectively dripped on LN plates, and the malassezia suspensions are uniformly coated for later use.
2. Uniformly wiping the surface of the pigskin with 0.5g of the shampoo samples prepared in examples 1-3 and comparative examples 1-5 for 1min, and rinsing the liquid soap on the pigskin with 100mL of sterile water for 1min for 2 times; after rinsing, placing the pigskin in a biological safety cabinet, ventilating and airing until no obvious water drops are generated on the surface of the pigskin, attaching the pigskin on a bacteria-dying plate for 15min, removing the pigskin after attaching, placing the plate in a (32+/-2) DEG C incubator for culturing for 72 hours, observing the growth condition of malassezia, and calculating the bacteriostasis rate, wherein the specific detection results are shown in the table 2 below.
TABLE 2
As can be seen from the detection data of the above Table 2, the shampoo compositions prepared in the examples 1-3 of the application have longer lasting antibacterial effect, the antibacterial performance is still more than 97% after 72 hours of use, while the antibacterial performance is obviously reduced after 1 hour of omitting the cacumen biotae extract in the comparative example 1, but the long-term antibacterial performance is better; comparative examples 2-3 changing the kind or ratio of the surfactant has a great influence on the long-term bacteriostasis performance; comparative examples 4-5 changing the mass ratio of conditioner, chelating agent and water-oil balancing agent would similarly affect the long-term bacteriostasis performance of the shampoo composition when not within the scope of the present application, that is, the shampoo composition protected by the present application has better bacteriostasis stability.
3.5 Alpha-reductase inhibition assay
The implementation principle is as follows: 5α -reductase is a protease produced in an amount that stimulates the conversion of testosterone (T) to Dihydrotestosterone (DHT) in the body, which causes androgenic alopecia when Dihydrotestosterone (DHT) accumulates to high levels in the skin. The pathogenesis of the hair follicle is that the Dihydrotestosterone (DHT) can inhibit the growth and development of hair follicles, the hair follicles are dysplasia and atrophy, the hair growth is naturally bad, in addition, the increase of the Dihydrotestosterone (DHT) level leads to the hypertrophy of sebaceous glands, the increase of grease secretion, and further the growth environment of the hair follicles is influenced, so that the higher the 5 alpha-reductase is, the heavier the hair loss is.
Materials and methods: 5α -reductase: extracting from rat prostate tissue, and storing at-80deg.C;
Positive control: finasteride 0.40 μm;
blank control: phosphate Buffered Saline (PBS);
other: testosterone, reduced coenzyme II, chloroform;
Sample preparation: taking 1g of shampoo compositions of the embodiments 1-3 and the comparative examples 1-5, adding 2ml of water to dissolve the shampoo compositions to obtain a dissolution liquid sample, and diluting the dissolution liquid sample with water to a test concentration of 1.00%;
The test process comprises the following steps: the 2mL reaction system contains: phosphate buffer (pH 6.5) 250. Mu.L, enzyme extract (1 mg/mL) 700. Mu.L, testosterone solution (0.5 mg/mL) 100. Mu.L, NADPH solution (1 mg/mL) 350. Mu.L; 600. Mu.L of 0.4. Mu.M finasteride was added to the positive control tube; 600. Mu.L of sample solution is added into the sample tube; 600. Mu.L of water was added to the complete reaction tube; the control tube replaced the enzyme extract with phosphate buffer (pH 6.5) and the reaction was stopped by adding 2.0mL of dichloromethane; the sample tube is reacted for 30min at 37 ℃, after the reaction is finished, 2.0mL of dichloromethane is added to stop the reaction, after shaking for 1min, the reaction is centrifuged for 10min at 3000 r/min. The upper aqueous phase was removed, about 1.0mL of the organic phase was removed and evaporated to dryness, and the residue was dissolved in 1.0mL of methanol and the testosterone peak area (T) was determined by high performance liquid chromatography. Each reaction was run in 3 parallel tubes, averaged, and the decimal place was retained, with the results shown in Table 3 below.
The calculation formula is as follows:
TABLE 3 Table 3
From the test results shown in Table 3, the shampoo compositions prepared in examples 1 to 3 of the application have a higher 5. Alpha. -reductase inhibition rate of 14% or more; whereas the omission of the biota orientalis extract 5α -reductase inhibition rate in comparative example 1 is significantly lower than that in the examples; the change of the types or the proportions of the surfactants in comparative examples 2 to 3 and the change of the mass ratio of the conditioner, the chelating agent and the water-oil balancing agent in comparative examples 4 to 5 can affect the inhibition rate of the shampoo composition to the 5α -reductase when the ratio is not within the protection scope of the application, so that the inhibition rate is obviously reduced, that is, only the shampoo composition protected by the application has better anti-falling effect.
The above examples are preferred embodiments of the present invention, but the embodiments of the present invention are not limited to the above examples, and any other changes, modifications, substitutions, combinations, and simplifications that do not depart from the spirit and principle of the present invention should be made in the equivalent manner, and the embodiments are included in the protection scope of the present invention.
Claims (11)
1. An anti-hair loss and hair-nourishing shampoo composition, which is characterized in that: the composition comprises the following components in percentage by weight: 4-6% of plant extract, 35-50% of surfactant, 0.1-0.5% of conditioner, 0.2-0.6% of antidandruff agent, 0.05-0.2% of chelating agent, 0.6-1.0% of preservative, 0.3-0.8% of aromatic, 0.1-0.3% of pH regulator, 0.05-0.15% of water-oil balancing agent and the balance of water;
the mass ratio of the conditioner to the chelating agent to the water-oil balancing agent is 1-5:0.5-2:0.5-1.5;
the plant extract is a mixture of rice chaff extract, ginger root extract, ginseng root extract, kelp extract, pomelo seed extract and centella asiatica extract, and the mass ratio of the rice chaff extract to the ginger root extract to the ginseng root extract to the kelp extract to the pomelo seed extract to the centella asiatica extract is 5:5:5:3.8:1.2.
2. The anti-hair loss, hair-growing shampoo composition according to claim 1, characterized in that: the surfactant is one or more selected from lauramidopropyl betaine, sodium C14-16 olefin sulfonate, sodium cocoyl isethionate, potassium cocoyl glycinate and sodium lauroyl glutamate.
3. The anti-hair loss, hair-growing shampoo composition according to claim 2, characterized in that: the surfactant is a mixture of lauramidopropyl betaine, sodium C14-16 olefin sulfonate, sodium cocoyl isethionate, potassium cocoyl glycinate and sodium lauroyl glutamate, and the mass ratio is 15-20:12-15:2-9:1.2-2.4:0.6-1.5.
4. A hair-setting and conditioning shampoo composition according to claim 3, characterized in that: the mass ratio of the lauramidopropyl betaine to the sodium C14-16 olefin sulfonate to the sodium cocoyl isethionate to the potassium cocoyl glycinate to the sodium lauroyl glutamate is 20:13:2:2:1.
5. The anti-hair loss, hair-growing shampoo composition according to claim 1, characterized in that: the conditioner is polyquaternium-10; the anti-dandruff agent is piroctone olamine salt; the chelating agent is hydroxyethyldiphosphate.
6. The anti-hair loss, hair-growing shampoo composition according to claim 1, characterized in that: the water-oil balancing agent is a mixture of gum arabic and salicylic acid.
7. The anti-hair loss, hair-growing shampoo composition according to claim 1, characterized in that: the mass ratio of the conditioner to the chelating agent to the water-oil balancing agent is 3:1:1.
8. The anti-hair loss, hair-growing shampoo composition according to claim 1, characterized in that: the hair-loss preventing and hair-growing shampoo composition also comprises a bacteriostatic agent, and 1-2% of biota orientalis extract in parts by weight.
9. The method for preparing the hair-loss preventing and hair-growing shampoo composition according to any one of claims 1 to 8, characterized in that: the method comprises the following steps:
(1) Adding lauramidopropyl betaine and C14-16 sodium olefin sulfonate into a stirring pot, homogenizing for 3 minutes, heating and stirring until the mixture is completely dissolved to obtain a mixture 1;
(2) Adding sodium cocoyl isethionate and polyquaternium-10 into the mixture 1, and keeping the temperature for 15 minutes to obtain a mixture 2;
(3) And cooling the mixture 2 to 45 ℃, adding the rest raw materials, and uniformly mixing to obtain the anti-hair loss hair-growing shampoo composition.
10. Use of an anti-hair loss, hair-growing shampoo composition according to any one of claims 1-8 for the preparation of a shampoo product.
11. The use according to claim 10, characterized in that: the shampoo product comprises shampoo, hair conditioner, shampoo cream or hair treatment cream.
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