CN117441010A - 从诱导多能干细胞产生α-βT细胞的组合物和方法 - Google Patents

从诱导多能干细胞产生α-βT细胞的组合物和方法 Download PDF

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Publication number
CN117441010A
CN117441010A CN202280040273.1A CN202280040273A CN117441010A CN 117441010 A CN117441010 A CN 117441010A CN 202280040273 A CN202280040273 A CN 202280040273A CN 117441010 A CN117441010 A CN 117441010A
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cell
cells
ipsc
seq
amino acid
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Chinese (zh)
Inventor
M·沃利特
K·圣斯特凡诺
B·萨兰特斯
M·门冬萨
西村聪修
M·F·纳索
B·古隆
祝增荣
B·莫尔斯
L·博尔格斯
J·M·卡顿
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Century Therapy Co ltd
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Century Therapy Co ltd
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CN202280040273.1A 2021-04-07 2022-04-04 从诱导多能干细胞产生α-βT细胞的组合物和方法 Pending CN117441010A (zh)

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US202163171650P 2021-04-07 2021-04-07
US63/171,650 2021-04-07
PCT/US2022/023347 WO2022216624A1 (en) 2021-04-07 2022-04-04 Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells

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CN117441010A true CN117441010A (zh) 2024-01-23

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US (1) US20220333074A1 (https=)
EP (1) EP4320224A1 (https=)
JP (1) JP2024513906A (https=)
CN (1) CN117441010A (https=)
AR (1) AR125313A1 (https=)
AU (1) AU2022255166A1 (https=)
CA (1) CA3214473A1 (https=)
TW (1) TW202305114A (https=)
WO (1) WO2022216624A1 (https=)

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IL314801A (en) 2022-02-22 2024-10-01 Juno Therapeutics Inc Proteinase 3 (PR3) Chimeric Autoantigen Receptor T Cells and Related Methods and Uses
JP2025522360A (ja) 2022-06-08 2025-07-15 センチュリー セラピューティクス，インコーポレイテッド Ｃｄ１６変異体およびｎｋｇ２ｄを発現する遺伝子操作した細胞ならびにその使用
KR20250143301A (ko) 2022-11-10 2025-10-01 센츄리 쎄라퓨틱스 인코포레이티드 항-넥틴4 키메라 항원 수용체를 갖는 유전자 조작 세포 및 이의 용도
EP4397680A1 (en) * 2022-12-29 2024-07-10 Keshihua (Nanjing) Biotechnology Co., Ltd Tcr, polypeptide, expression vector, host cell, pharmaceutical composition and method for obtaining tcr
WO2025101938A2 (en) 2023-11-10 2025-05-15 Century Therapeutics, Inc. Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof
WO2025106626A1 (en) 2023-11-15 2025-05-22 Century Therapeutics, Inc. Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof
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