CA3214473A1 - Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells - Google Patents

Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells Download PDF

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Publication number
CA3214473A1
CA3214473A1 CA3214473A CA3214473A CA3214473A1 CA 3214473 A1 CA3214473 A1 CA 3214473A1 CA 3214473 A CA3214473 A CA 3214473A CA 3214473 A CA3214473 A CA 3214473A CA 3214473 A1 CA3214473 A1 CA 3214473A1
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Prior art keywords
cell
ipsc
tcr
cells
seq
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CA3214473A
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English (en)
French (fr)
Inventor
Mark WALLET
Katherine SANTOSTEFANO
Brenda SALANTES
Mark MENDONCA
Toshinobu Nishimura
Michael Naso
Buddha GURUNG
Zengrong ZHU
Barry Morse
Luis Borges
Jill Marinari CARTON
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Century Therapeutics Inc
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Century Therapeutics Inc
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Publication of CA3214473A1 publication Critical patent/CA3214473A1/en
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    • C07K14/70503—Immunoglobulin superfamily
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    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
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CA3214473A 2021-04-07 2022-04-04 Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells Pending CA3214473A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163171650P 2021-04-07 2021-04-07
US63/171,650 2021-04-07
PCT/US2022/023347 WO2022216624A1 (en) 2021-04-07 2022-04-04 Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells

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CA3214473A1 true CA3214473A1 (en) 2022-10-13

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US (1) US20220333074A1 (https=)
EP (1) EP4320224A1 (https=)
JP (1) JP2024513906A (https=)
CN (1) CN117441010A (https=)
AR (1) AR125313A1 (https=)
AU (1) AU2022255166A1 (https=)
CA (1) CA3214473A1 (https=)
TW (1) TW202305114A (https=)
WO (1) WO2022216624A1 (https=)

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US20250066738A1 (en) * 2021-09-07 2025-02-27 Dana-Farber Cancer Institute, Inc. Induced pluripotent stem cells (ipsc), t-cell compositions and methods of use
IL314801A (en) 2022-02-22 2024-10-01 Juno Therapeutics Inc Proteinase 3 (PR3) Chimeric Autoantigen Receptor T Cells and Related Methods and Uses
JP2025522360A (ja) 2022-06-08 2025-07-15 センチュリー セラピューティクス，インコーポレイテッド Ｃｄ１６変異体およびｎｋｇ２ｄを発現する遺伝子操作した細胞ならびにその使用
AU2023375625A1 (en) 2022-11-10 2025-05-15 Century Therapeutics, Inc. Genetically engineered cells having anti-nectin4 chimeric antigen receptors, and uses thereof
EP4393942A1 (en) * 2022-12-29 2024-07-03 Keshihua (Nanjing) Biotechnology Co., Ltd Tcr, polypeptide, expression vector, host cell, pharmaceutical composition and method for obtaining tcr
WO2025101938A2 (en) 2023-11-10 2025-05-15 Century Therapeutics, Inc. Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof
WO2025106626A1 (en) 2023-11-15 2025-05-22 Century Therapeutics, Inc. Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof
WO2025237762A1 (en) 2024-05-14 2025-11-20 Englmeier Ludwig Matched t-cells and myeloid cells from cell culture

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