CN1171620C - Health-care food for improving sleep - Google Patents
Health-care food for improving sleep Download PDFInfo
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- CN1171620C CN1171620C CNB021333157A CN02133315A CN1171620C CN 1171620 C CN1171620 C CN 1171620C CN B021333157 A CNB021333157 A CN B021333157A CN 02133315 A CN02133315 A CN 02133315A CN 1171620 C CN1171620 C CN 1171620C
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- ganoderma
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- dry extract
- health food
- fructus schisandrae
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Abstract
The present invention relates to health care food for improving sleep. The present invention is characterized in that the present invention is prepared from spine date seeds, fructus schizandrae, white peony root, glossy ganoderma and ginseng. The present invention has the advantages that the effect of improving the sleep is obvious, and raw materials used by the present invention are medicine and food isogenous articles specified by the National Ministry of Health. The present invention is nontoxic and harmless to a human body and can be used as the health care food and medicine.
Description
The present invention relates to a kind of health food that improves sleep, is the health food of feedstock production specifically with the Chinese herbal medicine.
Insomnia is a kind of common disease.Insomnia makes the people show dejected, anxiety, can weaken immunologic mechanism simultaneously, hinders antisecosis.Along with the modern life rhythm and pace of moving things is accelerated, insomnia has the trend of increasing progressively.Write in " shallow view is with controlling insomnia drug exploitation " literary composition in 1999 the 10th the 7th phases of volume " time precious traditional Chinese medical science traditional Chinese medicines ", at present, it is many that Chinese and western medicine is used for the treatment of the medicine of insomnia, the Western medicine tool mainly is Benzodiazepines and phenobarbital class and chloral hydrate etc. than strong syngignoscism, life-time service can cause chronic poisoning or drug dependence, clinical use is subjected to certain limitation, and the traditional Chinese medical science is used to control the medicine or the health food of insomnia, or curative effect is not outstanding; Or medication inconvenience, or the medicine is expensive etc., always can not well satisfy people's needs.
The object of the present invention is to provide a kind of health food that improves sleep.
Solution of the present invention is based on theory of Chinese medical science, and in conjunction with modern pharmacological research, the homology article are eaten in drug of choice.Semen Ziziphi Spinosae is with nourishing the liver blood in the prescription, and tranquilizing mind is a principal agent; Mind tranquilizing and the heart calming on the one hand simultaneously again can the kidney invigorating Guyang, and then sun can be gone into the moon and then can be slept at nightfall; The Radix Paeoniae Alba yin fluid astringing that nourishes blood had both nourished blood and had enriched blood, and with nourishing the heart to keep a sound mind, nursed one's health it, in again can yin fluid astringing going into, had tranquilizing effect; The Ganoderma tranquilizing by nourishing the heart, invigorating qi and benefiting blood, giving consideration to both the incidental and fundamental; Radix Ginseng is calmed the nerves, and strongly invigorating primordial QI is then gone into sun with positive medicine and divided again, then goes into cloudy the branch with cloudy medicine, both can help the sedative action of Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, Ganoderma, can help the kidney invigorating Guyang of Fructus Schisandrae Chinensis, the Radix Paeoniae Alba again, the merit of yin fluid astringing.Make the interior negative and positive of body reach coordinated balance, then can wake up daytime, can sleep night.
The present invention is achieved through the following technical solutions:
It is made by Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Ganoderma, Radix Ginseng, and the proportioning of its composition is as follows:
Semen Ziziphi Spinosae 15-25 part Fructus Schisandrae Chinensis 10-20 part Radix Paeoniae Alba 4-12 part
Ganoderma 2-6 part Radix Ginseng 2-6 part
Above-mentioned each component is made production method of health food-Yizhibao is:
1, Radix Ginseng is cleaned up drying.Pulverize, sieve the Radix Ginseng fine powder.
2, Semen Ziziphi Spinosae, the Radix Paeoniae Alba are prepared by above-mentioned prescription after, decoct with water secondary, each 1-3 hour, 8-12 times of water gaging, extracting liquid filtering, it is 1.10 (70 ℃ of mensuration) that filtrate is concentrated into proportion, with this extractum liquid spray drying, dry extract.
3, Fructus Schisandrae Chinensis, Ganoderma are decocted secondary with 70% ethanol, each 1-3 hour, 8-12 doubly measured, extracting liquid filtering, and filtrate is reclaimed ethanol earlier, and reconcentration to proportion is 1.10 (70 ℃ of mensuration), with this extractum liquid spray drying, gets dry extract.
4, Radix Ginseng fine powder and Semen Ziziphi Spinosae, the Radix Paeoniae Alba are extracted gained dry extract and Fructus Schisandrae Chinensis, Ganoderma dry extract and prepare by above-mentioned formula proportion after, mix homogeneously is used 60% alcohol granulation, particle drying to moisture less than 5%.Filled capsules, promptly.
Advantage of the present invention is as follows: the first, and it is obvious to improve sleeper effect, based on theory of Chinese medical science, and in conjunction with the modern pharmacological research gained.The second, the raw material that the present invention selects for use all is the article of the integration of edible and medicinal herbs of health ministry regulation, and is nontoxic to human body, can make health food, can make medicine again.
For showing that the present invention improves the effect of sleep, make health care through West China HSPH of Sichuan University, promptly improve the sleep test, the result is as follows:
Prolong the inductive mouse sleep time test of pentobarbital sodium: one-level Kunming kind female mice is divided into 4 groups at random, be three dosage groups of the present invention and negative control group, three dosage groups are respectively: 170mg/kg.bw, 330mg/kg.bw, 500mg/kg.bw are equivalent to 10,20,30 times of human body recommended intake respectively.Diluent of the present invention is irritated stomach once by 2% volume every day, continuously around.Negative control group is irritated distilled water.Last is irritated stomach and is given each treated animal lumbar injection pentobarbital sodium 60mg/kg.bw after 30 minutes.Observe and write down the deep sleep persistent period of injection back animal.Calculate the average length of one's sleep of each treated animal respectively.The result shows: significantly be longer than matched group the average length of one's sleep of 330mg/kg.bw of the present invention, 500mg/kg.bw dosage group mice, i.e. the present invention has the prolongation effect to the inductive mouse sleep time of high dose pentobarbital sodium.Be that the present invention has the sleep of improvement effect.
Be embodiments of the invention below:
1 one kinds of health foods that improve sleep of embodiment are made up of Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Ganoderma, Radix Ginseng, and the proportioning of its composition is as follows:
7 parts of 14 portions of Radix Paeoniae Albas of 20 parts of Fructus Schisandrae Chinensis of Semen Ziziphi Spinosae
3 parts of 3 parts of Radix Ginsengs of Ganoderma
Production method:
1, Radix Ginseng is cleaned up, under 60 ℃, be dried to moisture less than 5%.Pulverize, cross 120 mesh sieves and get the Radix Ginseng fine powder.
2, Semen Ziziphi Spinosae, the Radix Paeoniae Alba are prepared by above-mentioned prescription after, decoct with water secondary, each 2 hours, 10 times of water gagings, extracting liquid filtering, it is 1.10 (70 ℃ of mensuration) that filtrate is concentrated into proportion, with this extractum liquid spray drying, dry extract.
3, Fructus Schisandrae Chinensis, Ganoderma are decocted secondary with 70% ethanol, each 2 hours, 10 times of amount 70% ethanol, extracting liquid filtering, filtrate is reclaimed ethanol earlier, and reconcentration to proportion is 1.10 (70 ℃ of mensuration), with this extractum liquid spray drying, gets dry extract.
4, Radix Ginseng fine powder and Semen Ziziphi Spinosae, the Radix Paeoniae Alba are extracted gained dry extract and Fructus Schisandrae Chinensis, Ganoderma dry extract and prepare by above-mentioned formula proportion after, mix homogeneously is used 60% alcohol granulation, particle drying to moisture less than 5%.Filled capsules, promptly.
2 one kinds of health foods that improve sleep of embodiment are made up of Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Ganoderma, Radix Ginseng, and the percentage by weight of its composition is as follows:
6 parts of 18 portions of Radix Paeoniae Albas of 18 parts of Fructus Schisandrae Chinensis of Semen Ziziphi Spinosae
4 parts of 5 parts of Radix Ginsengs of Ganoderma
Production method is with embodiment 1.
3 one kinds of health foods that improve sleep of embodiment are made up of Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Ganoderma, Radix Ginseng, and the percentage by weight of its composition is as follows:
11 parts of 12 portions of Radix Paeoniae Albas of 22 parts of Fructus Schisandrae Chinensis of Semen Ziziphi Spinosae
5 parts of 3 parts of Radix Ginsengs of Ganoderma
Production method is with embodiment 1.
Claims (3)
1, a kind of health food that improves sleep is characterized in that it is made by following materials of weight proportions:
Semen Ziziphi Spinosae 15-25 part Fructus Schisandrae Chinensis 10-20 part Radix Paeoniae Alba 4-12 part
Ganoderma 2-6 part Radix Ginseng 2-6 part.
2, the health food of improvement sleep according to claim 1, the dosage form that it is characterized in that this health food is a capsule.
3, the preparation method of the health food that described improvement is slept according to claim 2, it is characterized in that Radix Ginseng is cleaned up, drying is pulverized, sieve the Radix Ginseng fine powder, Semen Ziziphi Spinosae, after the Radix Paeoniae Alba prepares by above-mentioned prescription, decoct with water secondary, each 1-3 hour, 8-12 times of water gaging, extracting liquid filtering, filtrate is concentrated into and measures proportion at 70 ℃ is 1.10, with this extractum liquid spray drying, gets dry extract, Fructus Schisandrae Chinensis, Ganoderma decocts secondary with 70% ethanol, each 1-3 hour, 8-12 doubly measured, extracting liquid filtering, filtrate is reclaimed ethanol earlier, reconcentration is 1.10 to measuring proportion at 70 ℃, with this extractum liquid spray drying, gets dry extract, with Radix Ginseng fine powder and Semen Ziziphi Spinosae, the Radix Paeoniae Alba is extracted gained dry extract and Fructus Schisandrae Chinensis, after the Ganoderma dry extract prepares in proportion, mix homogeneously is used 60% alcohol granulation, particle drying to moisture less than 5%, filled capsules makes capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021333157A CN1171620C (en) | 2002-06-20 | 2002-06-20 | Health-care food for improving sleep |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021333157A CN1171620C (en) | 2002-06-20 | 2002-06-20 | Health-care food for improving sleep |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1390590A CN1390590A (en) | 2003-01-15 |
| CN1171620C true CN1171620C (en) | 2004-10-20 |
Family
ID=4747144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021333157A Expired - Lifetime CN1171620C (en) | 2002-06-20 | 2002-06-20 | Health-care food for improving sleep |
Country Status (1)
| Country | Link |
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| CN (1) | CN1171620C (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100398119C (en) * | 2005-03-10 | 2008-07-02 | 香港生物科技研究院有限公司 | Medicine for improving sleep quality and its preparation method |
| CN101850001B (en) * | 2009-03-31 | 2013-08-28 | 北京因科瑞斯医药科技有限公司 | Pharmaceutical composition with function of improving sleep and preparation method thereof |
| CN102771784A (en) * | 2011-12-05 | 2012-11-14 | 王宁 | Health-care food for nourishing liver blood and tranquilizing mind |
| CN102630934A (en) * | 2011-12-21 | 2012-08-15 | 王广仪 | Micro-element oral liquid capable of regulating blood sugar and blood lipid |
| CN103039996A (en) * | 2012-12-28 | 2013-04-17 | 杨石 | Health food with function of improving sleep |
| CN103099191B (en) * | 2013-02-07 | 2014-07-30 | 贵州神奇投资有限公司 | Tomato spicy sauce with effect of improving sleeping and producing method |
| CN103340407B (en) * | 2013-07-23 | 2015-07-22 | 四川省中医药科学院 | Composition with sleep improving effect as well as preparation method and use of composition |
| CN104432000A (en) * | 2013-09-18 | 2015-03-25 | 中国医学科学院药用植物研究所海南分所 | Sleep improving health-care food and preparation method thereof |
| CN103816244B (en) * | 2014-01-20 | 2015-02-04 | 天津铸源健康科技集团有限公司 | Health product for improving sleep and preparation method and application thereof |
| CN104223066A (en) * | 2014-09-02 | 2014-12-24 | 上海焦点生物技术有限公司 | Traditional Chinese medicine composition for improving sleeping |
| CN104337920B (en) * | 2014-10-24 | 2017-02-22 | 甘肃扶正药业科技股份有限公司 | Traditional Chinese medicine composition for improving sleep quality |
| CN106578296A (en) * | 2016-11-23 | 2017-04-26 | 天津金匮堂生物科技有限公司 | Formula of spina date seed tabletted candy and preparation method thereof |
| CN106858255A (en) * | 2017-04-07 | 2017-06-20 | 福州美瑞蒂恩生物科技有限公司 | One kind improves the health care of sleep composition and its application |
-
2002
- 2002-06-20 CN CNB021333157A patent/CN1171620C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1390590A (en) | 2003-01-15 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: CHENGDU KANGHONG MEDICINE GROUP CO.LTD. Free format text: FORMER OWNER: CHENGDU KANGHONG TECHNOLOGY INDUSTRIAL (GROUP) CO., LTD. Effective date: 20080926 |
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| C41 | Transfer of patent application or patent right or utility model | ||
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Effective date of registration: 20080926 Address after: No 36, Shu West Road, Chengdu, Sichuan, Jinniu District Patentee after: CHENGDU KANGHONG PHARMACEUTICAL Co.,Ltd. Address before: No 36, Shu West Road, Chengdu, Sichuan, Jinniu District Patentee before: Chengdu Kanghong technology industry (Group) Co.,Ltd. |
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| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20210302 Address after: 611930 No.89 Hualong Road, Tianpeng Town, Pengzhou City, Chengdu City, Sichuan Province Patentee after: Sichuan Jishengtang Pharmaceutical Co.,Ltd. Address before: 610036 No. 36 Shu West Road, Chengdu, Sichuan, Jinniu District Patentee before: CHENGDU KANGHONG PHARMACEUTICAL Co.,Ltd. |
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| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20041020 |