CN106237075A - A kind of have resisting fatigue and promote the food of attention effect, health product or pharmaceutical composition and its production and use - Google Patents
A kind of have resisting fatigue and promote the food of attention effect, health product or pharmaceutical composition and its production and use Download PDFInfo
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- 235000013305 food Nutrition 0.000 title claims abstract description 29
- 230000000694 effects Effects 0.000 title claims abstract description 23
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 7
- 238000004519 manufacturing process Methods 0.000 title description 2
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- 239000003814 drug Substances 0.000 claims abstract description 36
- 238000002360 preparation method Methods 0.000 claims abstract description 31
- 241000208340 Araliaceae Species 0.000 claims abstract description 23
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 23
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 23
- 235000008434 ginseng Nutrition 0.000 claims abstract description 23
- 240000001008 Dimocarpus longan Species 0.000 claims abstract description 15
- 235000000235 Euphoria longan Nutrition 0.000 claims abstract description 15
- 239000002994 raw material Substances 0.000 claims abstract description 12
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- 239000000843 powder Substances 0.000 claims description 18
- 239000000047 product Substances 0.000 claims description 18
- 229940079593 drug Drugs 0.000 claims description 15
- 239000012141 concentrate Substances 0.000 claims description 14
- 239000002671 adjuvant Substances 0.000 claims description 10
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- 238000000034 method Methods 0.000 claims description 8
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- 230000000295 complement effect Effects 0.000 claims description 4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention provides and a kind of there is resisting fatigue and promote the food of attention effect, health product or pharmaceutical composition, it is the preparation being prepared from by the raw material of following weight proportioning: 1 20 parts of Fructus Jujubae, Rhizoma Dioscoreae 1 20 parts, Radix Ginseng 1 40 parts, Rhizoma Polygonati 1 40 parts, Arillus Longan 1 20 parts, Fructus Crataegi 1 20 parts, Fructus Lycii 1 40 parts.Present invention also offers preparation method and the purposes of foregoing.Safely, effectively, effect of resisting fatigue and raising attention is excellent, and preparation method is simple, can be prepared as food, health food or medicine, has stronger actual application value for the present composition.
Description
Technical field
The present invention relates to a kind of have resisting fatigue and promote the food of attention effect, health product or pharmaceutical composition and
Preparation Method And The Use.
Background technology
Tired also known as tired be the discomfort of subjective a kind of fatigue and weak, feeling fatigue is not specific symptoms, a lot of diseases
All can cause fatigue, ill after feel that situation the most not in harmony is the most common, various disease causes fatigue in various degree, some
Disease performance becomes apparent from sometimes can be as medical onset symptoms.Attention is difficult to concentration may cause study and work efficient
Under, sleep, pressure, age, the mental status, environment etc. are all scatterbrained inducements.Tired and absent minded all
Being a kind of typical subhealthy status, the most extremely common, especially intellectual work is main professional population.
Modern medicine there is no clear and definite Therapeutic Method to this, and the traditional Chinese medical science then thinks that the tired deficiency syndrome for unit's QI consumed wound become with psychology
Change caused by (or the most smooth) double factor.Qi-restoratives righting is not only wanted, tired calming the nerves of also should dispelling in treatment.On the one hand, qi-restoratives primordial QI reinforcing, nourishes
Body, empty must mend, and canonical is prosperous, tired from removing；On the other hand, adjust smooth will, comfortable smooth meaning, refreshing must pacify, the heart is then peaceful, and fatigue can
Disappear.In medicinal application, frequently with Radix Panacis Quinquefolii or Radix Codonopsis, Rhizoma Atractylodis Macrocephalae (parched), Poria, Radix Astragali Preparata, Rhizoma Dioscoreae, Fructus Amomi, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae, the Radix Aucklandiae,
The medicines such as Endothelium Corneum Gigeriae Galli, Semen Raphani, Caulis Perillae, Herba Pogostemonis, Radix Glycyrrhizae, carry out formula according to patient's concrete condition.Attention is not collected
In, also frequently with said medicine prescription, or add the Fructus Alpiniae Oxyphyllae class Chinese medicines such as Fructus Alpiniae Oxyphyllae.
But these drug prescription long-term takings all may have toxic and side effects in various degree, and general subhealthy status crowd is very
Difficult seeking medical advice because of the problem such as tired, absent minded, medication probability itself is relatively low.
Summary of the invention
The technical scheme is that provide a kind of have resisting fatigue and promote the food of attention effect, health product or
Person's pharmaceutical composition.The present composition uses the Chinese medicine composition of integration of edible and medicinal herbs, has long-term edible history and Clinical practice
Experience, thus there is the high feature with definite effect of safety.As daily edible in added in food, then can be greatly improved audient's
Compliance, it is achieved it improves fatigue effect, improves attention.
The present invention has resisting fatigue and promotes the food of attention effect, health product or pharmaceutical composition, it is characterized in that:
It is the preparation being prepared from by the raw material of following weight proportioning: Fructus Jujubae 1-20 part, Rhizoma Dioscoreae 1-20 part, Radix Ginseng 1-40 part, Rhizoma Polygonati
1-40 part, Arillus Longan 1-20 part, Fructus Crataegi 1-20 part, Fructus Lycii 1-40 part.
Preferably, described compositions it be the preparation being prepared from by the raw material of following weight proportioning: Fructus Jujubae 5-10 part, mountain
Medicine 5-10 part, Radix Ginseng 20-40 part, Rhizoma Polygonati 5-20 part, Arillus Longan 5-10 part, Fructus Crataegi 5-10 part, Fructus Lycii 20-40 part.The most excellent
Selection of land, described compositions it be the preparation being prepared from by the raw material of following weight proportioning: 10 parts of Fructus Jujubae, Rhizoma Dioscoreae 10 parts, Radix Ginseng
30 parts, Rhizoma Polygonati 10 parts, Arillus Longan 10 parts, Fructus Crataegi 5 parts, Fructus Lycii 25 parts；Or be prepared from by the raw material of following weight proportioning
Preparation: 5 parts of Fructus Jujubae, Rhizoma Dioscoreae 5 parts, Radix Ginseng 35 parts, Rhizoma Polygonati 15 parts, Arillus Longan 10 parts, Fructus Crataegi 10 parts, Fructus Lycii 20 parts.
Preferably, described compositions is the protogenic medicinal powder of aforementioned base materials or water or extractive with organic solvent, adds food
The preparation that field, field of health care products or pharmaceutically acceptable adjuvant or complementary composition are prepared from.Preferably, described system
Agent is oral formulations or enteral nutrition agent.
Preferably, described preparation is powder, granule, tablet, suspensoid or capsule.
Present invention also offers a kind of method preparing foregoing, it is characterised in that: it comprises the steps of:
(1) weighting raw materials；
(2) crude drug directly beats powder, or by crude drug boiling or organic solvent extraction, extracting solution concentrates, adds
Field of food, field of health care products or pharmaceutically acceptable adjuvant or complementary composition are prepared as preparation.
Preferably, described extracting method is: take crude drug, with water extraction, filters, merging filtrate, concentrates, add ethanol and make to contain
Alcohol amount reaches 80%v/v, stands and solid-liquid separation, takes supernatant, reclaims ethanol, concentrates, is dried,.
Preferably, described extracting method is: take crude drug, uses 60% ethanol extraction, filters, merging filtrate, concentrate drying,
?.
Present invention also offers foregoing preparation resisting fatigue and/or improve the food of attention, health product or
Purposes in medicine.
The present invention has resisting fatigue and promotes the compositions of attention effect, is that inventor combines length at abundant theoretical background
Formed in the case of phase Clinical Experience.Said composition is made up of seven kinds of integration of edible and medicinal herbs Chinese medicines, and effect experiment shows that it can
Strengthen mouse anti-reflecting fatigue and hypoxia-bearing capability, it is possible to improve mice attention, and effect be superior to the medicines such as Radix Ginseng and be used alone,
Prove that medicine of the present invention has played the effect of Synergistic.
Present composition safety, effectively, effect of resisting fatigue and raising attention is excellent, and preparation method is simple, can make
For becoming food, health food or medicine, provide a kind of new selection for actually used.
Obviously, according to the foregoing of the present invention, according to ordinary technical knowledge and the customary means of this area, without departing from
Under the present invention above-mentioned basic fundamental thought premise, it is also possible to make the amendment of other various ways, replace or change.
The detailed description of the invention of form by the following examples, remakes the most specifically the foregoing of the present invention
Bright.But this should not being interpreted as, the scope of the above-mentioned theme of the present invention is only limitted to Examples below.All based on foregoing of the present invention
The technology realized belongs to the scope of the present invention.
Detailed description of the invention
The raw material, the equipment that use in the specific embodiment of the invention are known product, obtain by buying commercially available prod.
The preparation of embodiment 1 present composition
Take Fructus Jujubae 10kg, Rhizoma Dioscoreae 10kg, Radix Ginseng 30kg, Rhizoma Polygonati 10kg, Arillus Longan 10kg, Fructus Crataegi 5kg, Fructus Lycii 25kg, use
Water reflux, extract, 2 times, adds 12 times of volumes for the first time, and second time adds 10 times of volumes, every time backflow 2 hours, filters, and merges filter
Liquid, is concentrated into relative density about 1.25g/ml, adds ethanol and makes alcohol content reach about 80%v/v, stands and solid-liquid separation, take supernatant
Liquid, reclaims ethanol, concentrates, is dried, extract obtained pulverized 60 mesh sieves, and obtained extract powder 31kg of the present invention.
Take extract powder of the present invention, add field of food, field of health care products or pharmaceutically acceptable adjuvant or auxiliary
Helping property composition, prepares food of the present invention, health food or medicine.
The preparation of embodiment 2 present composition
Take Fructus Jujubae 10kg, Rhizoma Dioscoreae 10kg, Radix Ginseng 40kg, Rhizoma Polygonati 20kg, Arillus Longan 5kg, Fructus Crataegi 5kg, Fructus Lycii 15kg, use water
Reflux, extract, 2 times, adds 10 times of volumes for the first time, and second time adds 8 times of volumes, every time backflow 2 hours, filters, merging filtrate,
Concentrate drying, extract obtained pulverized 60 mesh sieves, obtained extract powder 26kg of the present invention.
Take extract powder of the present invention, add field of food, field of health care products or pharmaceutically acceptable adjuvant or auxiliary
Helping property composition, prepares food of the present invention, health food or medicine.
The preparation of embodiment 3 present composition
Take Fructus Jujubae 5kg, Rhizoma Dioscoreae 5kg, Radix Ginseng 35kg, Rhizoma Polygonati 15kg, Arillus Longan 10kg, Fructus Crataegi 10kg, Fructus Lycii 20kg, add
60% alcohol reflux 3 times, adds for the first time 8 times of volumes, second time and third time and adds 6 times of volumes respectively, refluxes 1 every time
～2 hours, filter, merging filtrate, reclaim ethanol, concentrate, be dried, extract obtained pulverizing, obtain extract powder of the present invention
20kg。
Take extract powder of the present invention, add field of food, field of health care products or pharmaceutically acceptable adjuvant or auxiliary
Helping property composition, prepares food of the present invention, health food or medicine.
The preparation of embodiment 4 present composition
Take Fructus Jujubae 5kg, Rhizoma Dioscoreae 5kg, Radix Ginseng 20kg, Rhizoma Polygonati 5kg, Arillus Longan 20kg, Fructus Crataegi 10kg, Fructus Lycii 40kg, add
60% alcohol reflux 3 times, adds for the first time 8 times of volumes, second time and third time and adds 6 times of volumes respectively, refluxes 1 every time
～2 hours, filter, merging filtrate, reclaim ethanol, concentrate, be dried, extract obtained pulverizing, obtain extract powder of the present invention
20kg。
Take extract powder of the present invention, add field of food, field of health care products or pharmaceutically acceptable adjuvant or auxiliary
Helping property composition, prepares food of the present invention, health food or medicine.
The preparation of embodiment 5 present composition
Take Fructus Jujubae 1kg, Rhizoma Dioscoreae 20kg, Radix Ginseng 1kg, Rhizoma Polygonati 40kg, Arillus Longan 1kg, Fructus Crataegi 20kg, Fructus Lycii 1kg, add 60%
Alcohol reflux 3 times, adds 8 times of volumes, second time and third time for the first time and adds 6 times of volumes respectively, backflow 1～2 every time
Hour, filter, merging filtrate, reclaim ethanol, concentrate, be dried, extract obtained pulverizing, obtain extract powder 20kg of the present invention.
Take extract powder of the present invention, add field of food, field of health care products or pharmaceutically acceptable adjuvant or auxiliary
Helping property composition, prepares food of the present invention, health food or medicine.
The preparation of embodiment 6 present composition
Take Fructus Jujubae 20kg, Rhizoma Dioscoreae 1kg, Radix Ginseng 20kg, Rhizoma Polygonati 1kg, Arillus Longan 20kg, Fructus Crataegi 20kg, Fructus Lycii 1kg, add
60% alcohol reflux 3 times, adds for the first time 8 times of volumes, second time and third time and adds 6 times of volumes respectively, refluxes 1 every time
～2 hours, filter, merging filtrate, reclaim ethanol, concentrate, be dried, extract obtained pulverizing, obtain extract powder of the present invention
20kg。
Take extract powder of the present invention, add field of food, field of health care products or pharmaceutically acceptable adjuvant or auxiliary
Helping property composition, prepares food of the present invention, health food or medicine.
Beneficial effects of the present invention is proved below by way of experimental example.
The impact on tired mice of experimental example 1 present composition
KM mice 70, is divided into 7 groups by body weight stratified random, respectively model control group (0.5% tragacanth), sun
Property matched group (Radix Ginseng total saponins), the compositions side's group compositions of preparation (embodiment 1) entirely, Rhizoma Dioscoreae group, Rhizoma Polygonati group, Radix Ginseng group,
Fructus Lycii group.Gavage gives trial drug or suspensoid, every day 1 time, continuous 14d.30min after last administration, to the weight of animals 5%
Heavy burden be placed in water, water temperature 25 degrees Celsius, deep 30cm, it is swimming time that record puts into the time in water to animal dead.
Table 1 compositions and part composition medicine on the impact of heavy burden mice swimming time (n=10,)
| Group | Dosage | Swimming time (min) |
| Model comparison | —— | 11.3±2.4 |
| Positive control (Radix Ginseng total saponins) | 0.1g/kg | 16.9±9.0 |
| Compositions | 0.4g/kg | 16.6±5.2* |
| Fructus Jujubae | 0.4g/kg | 13.5±4.1 |
| Rhizoma Dioscoreae | 0.4g/kg | 12.3±3.6 |
| Rhizoma Polygonati | 0.4g/kg | 11.4±2.5 |
| Radix Ginseng | 0.4g/kg | 14.1±3.3* |
| Fructus Lycii | 0.4g/kg | 12.6±2.6 |
| Fructus Crataegi | 0.4g/kg | 11.9±2.8 |
Compare with model control group, * P ＜ 0.05, * * P ＜ 0.01
Result is as shown in table 1.Present composition extract gives 14 in 0.4g/kg dosage gavage, can significantly extend
Heavy burden mice swimming time, there was no significant difference with Radix Ginseng total saponins matched group；Radix Ginseng group also has preferably effect, but effect is than this
Inventive composition group is poor；Single medicine no significant difference compared with matched group in other compositionss.
Experimental result illustrates, the present composition can improve tired adaptibility to response, and effect is better than being used alone it
Any one of medicine, illustrate that each medicine in prescription of the present invention is playing the effect of Synergistic.And, medicine of the present invention
Compositions uses the medicines such as the cheap Fructus Jujubae of price comparison, Fructus Crataegi, Fructus Lycii to use with Radix Ginseng prescription, not only increases effect, also
Considerably reduce cost.
Experimental example 2 present composition intervenes the clinical observation of attention
Collection 20 readme attention adult of being difficult to concentrate, the age 19-50 year between.Use Shu Er special formula lattice amount
Table assessment volunteer's attention, and 2 groups it are divided into immediately by attention, 1 group is treatment group, and 2 groups is matched group.Treatment group patient
Every day edible nourishing stick with paste 30g, wherein in embodiment 3 preparation the present composition nutrition stick with paste in ratio be 16%.Matched group
Give the nutrition without the present composition and stick with paste 30g.Nutrition is stuck with paste and is made up of Semen Phaseoli, Semen Maydis etc..Volunteer eat 1 month after again
Scale is used to carry out attention assessment.Result such as table 2.
The clinical observation to intervening attention of table 2 present composition
Note: compare with matched group: * P ＜ 0.05；* P ＜ 0.01
Experimental result: the edible nutrition containing 16% present composition is stuck with paste, and is remarkably improved absent minded crowd
Attention scale score, it was demonstrated that the present composition has and preferably improves attention effect.
To sum up, present composition safety, effectively, effect of resisting fatigue and raising attention is excellent, and preparation method is simple,
Can be prepared as food, health food or medicine, with low cost, there is preferable market application foreground.
Claims (10)
1. there is resisting fatigue and promote the food of attention effect, health product or a pharmaceutical composition, it is characterized in that: it is
The preparation being prepared from by the raw material of following weight proportioning: Fructus Jujubae 1-20 part, Rhizoma Dioscoreae 1-20 part, Radix Ginseng 1-40 part, Rhizoma Polygonati 1-40
Part, Arillus Longan 1-20 part, Fructus Crataegi 1-20 part, Fructus Lycii 1-40 part.
Compositions the most according to claim 1, it is characterised in that: it is to be prepared from by the raw material of following weight proportioning
Preparation: Fructus Jujubae 5-10 part, Rhizoma Dioscoreae 5-10 part, Radix Ginseng 20-40 part, Rhizoma Polygonati 5-20 part, Arillus Longan 5-10 part, Fructus Crataegi 5-10 part, Chinese holly
Qi 20-40 part.
Compositions the most according to claim 2, it is characterised in that: it is to be prepared from by the raw material of following weight proportioning
Preparation: 10 parts of Fructus Jujubae, Rhizoma Dioscoreae 10 parts, Radix Ginseng 30 parts, Rhizoma Polygonati 10 parts, Arillus Longan 10 parts, Fructus Crataegi 5 parts, Fructus Lycii 25 parts；
Or the preparation being prepared from by the raw material of following weight proportioning:
5 parts of Fructus Jujubae, Rhizoma Dioscoreae 5 parts, Radix Ginseng 35 parts, Rhizoma Polygonati 15 parts, Arillus Longan 10 parts, Fructus Crataegi 10 parts, Fructus Lycii 20 parts.
4. according to the compositions described in claim 1-3 any one, it is characterised in that: it be aforementioned base materials protogenic medicinal powder or
Person's water or extractive with organic solvent, add field of food, field of health care products or pharmaceutically acceptable adjuvant or complementary one-tenth
Divide the preparation being prepared from.
5. according to the compositions described in claim 1-4 any one, it is characterised in that: described preparation is oral formulations or intestinal
Nutrient.
Pharmaceutical composition the most according to claim 5, it is characterised in that: described preparation is powder, granule, tablet, mixes
Suspension or capsule.
7. prepare the method for compositions described in claim 1-6 any one for one kind, it is characterised in that: it comprises the steps of:
(1) weighting raw materials；
(2) crude drug directly beats powder, or by crude drug boiling or organic solvent extraction, extracting solution concentrates, adds food
Field, field of health care products or pharmaceutically acceptable adjuvant or complementary composition are prepared as preparation.
Method the most according to claim 7, it is characterised in that: described extracting method is: take crude drug, with water extraction, filter
Cross, merging filtrate, concentrate, add ethanol and make alcohol content reach 80%v/v, stand and solid-liquid separation, take supernatant, reclaim ethanol, dense
Contract, be dried,.
Method the most according to claim 7, it is characterised in that: described extracting method is: take crude drug, carries with 60% ethanol
Take, filter, merging filtrate, concentrate drying,.
10. claim 1-6 any one compositions preparation resisting fatigue and/or improve the food of attention, health product or
Purposes in medicine.
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| CN201610664637.XA CN106237075B (en) | 2016-08-12 | 2016-08-12 | Food, health-care product or pharmaceutical composition with anti-fatigue and attention-improving functions as well as preparation method and application thereof |
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| CN201610664637.XA CN106237075B (en) | 2016-08-12 | 2016-08-12 | Food, health-care product or pharmaceutical composition with anti-fatigue and attention-improving functions as well as preparation method and application thereof |
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| CN109646590A (en) * | 2018-12-27 | 2019-04-19 | 北京康比特体育科技股份有限公司 | A kind of composition and its application for preventing to move low blood testis |
| CN109874952A (en) * | 2019-03-28 | 2019-06-14 | 广西中医药大学 | A kind of shellfish meat Anti-fatigue drink and preparation method thereof |
| CN110679815A (en) * | 2019-11-21 | 2020-01-14 | 湖南尚道生物科技有限公司 | Medicinal and edible compound health-care beverage with anti-fatigue and anti-hypoxia functions and preparation method thereof |
| CN111728216A (en) * | 2020-07-06 | 2020-10-02 | 北京理工亘舒科技有限公司 | Medicated diet vegetarian product and preparation method and application thereof |
| CN111802541A (en) * | 2020-07-27 | 2020-10-23 | 中国药科大学 | Traditional Chinese medicine plant beverage and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106237075B (en) | 2020-12-25 |
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