CN103169811A - Health care medicine for improving sleep and production method - Google Patents
Health care medicine for improving sleep and production method Download PDFInfo
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- CN103169811A CN103169811A CN201110430420XA CN201110430420A CN103169811A CN 103169811 A CN103169811 A CN 103169811A CN 201110430420X A CN201110430420X A CN 201110430420XA CN 201110430420 A CN201110430420 A CN 201110430420A CN 103169811 A CN103169811 A CN 103169811A
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Abstract
The invention relates to a health care medicine for improving sleep and a production method, which is characterized in that the health care medicine is prepared by spine date seed, Chinese magnoliavine, white peony root, matrimony vine and gen-seng. The invention has the advantage of obvious improvement on sleep effect. The present invention also has the advantage that adopted raw materials are all medicine-food homologous objects specified by the Chinese ministry of health and do no have toxin and harm to human bodies, and can be the health care medicine.
Description
Technical field
The present invention relates to a kind of health care medicine and manufacture method of improving sleep, belong to health care medicine and manufacture method technical field.
Background technology
Insomnia is a kind of common disease.Insomnia makes the people show dejected, anxiety, can weaken immunologic mechanism simultaneously, hinders antisecosis.Along with the modern life rhythm and pace of moving things is accelerated, insomnia has the trend of increasing progressively.Write in " shallow view is with controlling insomnia drug exploitation " literary composition in " time precious traditional Chinese medical science traditional Chinese medicines " of the 10th the 7th phase of volume in 1999, at present, it is many that Chinese and western medicine is used for the treatment of the medicine of insomnia, the stronger syngignoscism of Western medicine tool be mainly Benzodiazepines and phenobarbital class and chloral hydrate etc., life-time service can cause chronic poisoning or drug dependence, clinical use is subject to certain limitation, and the traditional Chinese medical science is used for controlling medicine or the health care medicine of insomnia, or curative effect is not outstanding; Or medication inconvenience, or the medicine is expensive etc., always can not well satisfy people's needs.
Summary of the invention
The object of the present invention is to provide a kind of health care medicine that improves sleep.
Solution of the present invention is take theory of Chinese medical science as the basis, and in conjunction with modern pharmacological research, the homology article are eaten in drug of choice.In formula, Semen Ziziphi Spinosae is with nourishing the liver blood, and tranquilizing mind is principal agent; Mind tranquilizing and the heart calming on the one hand simultaneously again can the kidney invigorating Guyang, and sun can enter the moon and can sleep at nightfall; The Radix Paeoniae Alba yin fluid astringing that nourishes blood had both nourished blood and had enriched blood, and with nourishing the heart to keep a sound mind, nursed one's health it, in again can yin fluid astringing entering, had tranquilizing effect; The Fructus Lycii tranquilizing by nourishing the heart, invigorating qi and benefiting blood, giving consideration to both the incidental and fundamental; Radix Ginseng is calmed the nerves, and strongly invigorating primordial QI, enter sun with positive medicine and divide again, enters cloudy minute with cloudy medicine, both can help the sedative action of Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, Fructus Lycii, can help again the kidney invigorating Guyang of Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, the merit of yin fluid astringing.Make the interior negative and positive of body reach coordinated balance, can wake up daytime, can sleep night.
The present invention is achieved through the following technical solutions:
It is made by Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Fructus Lycii, Radix Ginseng, and the proportioning of its composition is as follows:
Semen Ziziphi Spinosae 15-25 part Fructus Schisandrae Chinensis 10-20 part Radix Paeoniae Alba 4-12 part
Fructus Lycii 2-6 part Radix Ginseng 2-6 part
The production method that above-mentioned each component is made health care medicine is:
1, Radix Ginseng is cleaned up, drying is pulverized, and the Radix Ginseng fine powder sieves to get.
2, Semen Ziziphi Spinosae, the Radix Paeoniae Alba are prepared by above-mentioned formula after, decoct with water secondary, each 1-3 hour, 8-12 times of water gaging, extracting liquid filtering, it was 1.10(70 ℃ of mensuration that filtrate is concentrated into proportion), with this extractum liquid spray drying, get dry extract.
3, Fructus Schisandrae Chinensis, Fructus Lycii are decocted secondary with 70% ethanol, each 1-3 hour, 8-12 doubly measured, extracting liquid filtering, and filtrate is first reclaimed ethanol, reconcentration to proportion is 1.10(70 ℃ of mensuration), with this extractum liquid spray drying, get dry extract.
4, Radix Ginseng fine powder and Semen Ziziphi Spinosae, the Radix Paeoniae Alba are extracted gained dry extract and Fructus Schisandrae Chinensis, Chinese wolfberry fruit dry extract powder and prepare by above-mentioned formula proportion after, mix homogeneously is used 60% alcohol granulation, particle drying to moisture less than 5%.Filled capsules, and get final product.
Advantage of the present invention is as follows: the first, improve sleeper effect obvious, and take theory of Chinese medical science as the basis, and in conjunction with the modern pharmacological research gained; The second, the raw material that the present invention selects is all article of the integration of edible and medicinal herbs of health ministry regulation, and nontoxic to human body, medicine can keep healthy.
For showing that the present invention improves the effect of sleep, make health care through West China HSPH of Sichuan University, namely improve the sleep test, result is as follows:
Extend the mouse sleep time test that pentobarbital sodium is induced: one-level Kunming kind female mice is divided into 4 groups at random, be three dosage groups of the present invention and negative control group, three dosage groups are respectively: 170mg/kg.bw, 330mg/kg.bw, 500mg/kg.bw are equivalent to respectively 10,20,30 times of human body recommended intake.Diluent of the present invention is pressed 2% volume gavage every day once, continuously surrounding.Negative control group is filled with distilled water.The last gavage is given each treated animal lumbar injection pentobarbital sodium 60mg/kg.bw after 30 minutes.Observe and record the deep sleep persistent period of the rear animal of injection.Calculate respectively the average length of one's sleep of each treated animal.Result shows: significantly be longer than matched group the average length of one's sleep of 330mg/kg.bw of the present invention, 500mg/kg.bw dosage group mice, i.e. the mouse sleep time that the present invention induces high agent China ink pentobarbital sodium has the prolongation effect.Be that the present invention is improved the sleep effect.
The specific embodiment
Embodiment 1
A kind of health care medicine that improves sleep is comprised of Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Fructus Lycii, Radix Ginseng, and the proportioning of its composition is as follows:
7 parts of 14 portions of Radix Paeoniae Albas of 20 parts of Fructus Schisandrae Chinensis of Semen Ziziphi Spinosae
3 parts of 3 parts of Radix Ginsengs of Fructus Lycii
Production method:
1, Radix Ginseng is cleaned up, be dried to moisture less than 5% under 60 ℃.Pulverize, cross 120 mesh sieves and get the Radix Ginseng fine powder.
2, Semen Ziziphi Spinosae, the Radix Paeoniae Alba are prepared by above-mentioned formula after, decoct with water secondary, each 2 hours, 10 times of water gagings, extracting liquid filtering, it was 1.10(70 ℃ of mensuration that filtrate is concentrated into proportion), with this extractum liquid spray drying, get dry extract.
3, Fructus Schisandrae Chinensis, Fructus Lycii are decocted secondary with 70% ethanol, each 2 hours, 10 times of amount 70% ethanol, extracting liquid filtering, filtrate is first reclaimed ethanol, reconcentration to proportion is 1.10(70 ℃ of mensuration), with this extractum liquid spray drying, get dry extract.
4, Radix Ginseng fine powder and Semen Ziziphi Spinosae, the Radix Paeoniae Alba are extracted gained dry extract and Fructus Schisandrae Chinensis, Chinese wolfberry fruit dry extract powder and prepare by above-mentioned formula proportion after, mix homogeneously is used 60% alcohol granulation, particle drying to moisture less than 5%.Filled capsules, and get final product.
Claims (2)
1. health care medicine and a manufacture method of improving sleep, is characterized in that: the capsule that it is made by Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Fructus Lycii, Radix Ginseng.
2. the preparation method of the health food of the described improvement of claim 1 sleep, it is characterized in that: Radix Ginseng is cleaned up, and drying is pulverized, and the Radix Ginseng fine powder sieves to get; Semen Ziziphi Spinosae, the Radix Paeoniae Alba decoct with water secondary after preparing by above-mentioned formula, and each 1-3 hour, 8-12 times of water gaging, extracting liquid filtering, filtrate is concentrated into proportion for to be determined as 1.10 under 70 ℃ of conditions, with this extractum liquid spray drying, gets dry extract; Fructus Schisandrae Chinensis, Fructus Lycii decoct secondary with 70% ethanol, and each 1-3 hour, 8-12 doubly measured, extracting liquid filtering, and filtrate is first reclaimed ethanol, and reconcentration to proportion is 1.10 under 70 ℃ of conditions, with this extractum liquid spray drying, gets dry extract; After Radix Ginseng fine powder and Semen Ziziphi Spinosae, the Radix Paeoniae Alba were extracted gained dry extract and Fructus Schisandrae Chinensis, Chinese wolfberry fruit dry extract powder and prepare by above-mentioned formula proportion, mix homogeneously was used 60% alcohol granulation, particle drying to moisture less than 5%; Filled capsules makes capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110430420XA CN103169811A (en) | 2011-12-21 | 2011-12-21 | Health care medicine for improving sleep and production method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110430420XA CN103169811A (en) | 2011-12-21 | 2011-12-21 | Health care medicine for improving sleep and production method |
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| CN103169811A true CN103169811A (en) | 2013-06-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201110430420XA Pending CN103169811A (en) | 2011-12-21 | 2011-12-21 | Health care medicine for improving sleep and production method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103535734A (en) * | 2013-11-05 | 2014-01-29 | 广东生命一号药业有限公司 | Drug bag for improving sleep and preparation method thereof |
| CN104137990A (en) * | 2014-07-31 | 2014-11-12 | 溧阳市天目湖保健品有限公司 | Health food for improving memory and preparation method thereof |
-
2011
- 2011-12-21 CN CN201110430420XA patent/CN103169811A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103535734A (en) * | 2013-11-05 | 2014-01-29 | 广东生命一号药业有限公司 | Drug bag for improving sleep and preparation method thereof |
| CN103535734B (en) * | 2013-11-05 | 2016-03-30 | 广东生命一号药业有限公司 | Bagged instant preparation of a kind of improving water flood and preparation method thereof |
| CN104137990A (en) * | 2014-07-31 | 2014-11-12 | 溧阳市天目湖保健品有限公司 | Health food for improving memory and preparation method thereof |
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Legal Events
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| C06 | Publication | ||
| PB01 | Publication | ||
| C05 | Deemed withdrawal (patent law before 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130626 |