CN117159664A - Traditional Chinese medicine granule formula for treating gastric ulcer and duodenal ulcer and preparation method thereof - Google Patents
Traditional Chinese medicine granule formula for treating gastric ulcer and duodenal ulcer and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine granule formula for treating gastric ulcer and duodenal ulcer, which integrates a plurality of traditional Chinese medicine granules and is prepared into a compound formula mainly comprising the functions of activating blood circulation, removing blood stasis, dredging collaterals, relieving pain, regulating qi and blood, reducing swelling and promoting granulation according to a prescription specified proportion. The formula comprises ginseng, vinegar rhizoma corydalis, pseudo-ginseng, fructus amomi, safflower, bletilla striata, dandelion, radix bupleuri, fructus aurantii, liquorice, radix curcumae, dried orange peel, angelica sinensis, radix saposhnikoviae, white paeony root, roasted malt, roasted medicated leaven and roasted hawthorn. The invention relates to a Chinese medicinal granule formulation for treating chronic gastric ulcer and duodenal ulcer, which has good regulating effect on gastric cavity pain, fullness, nausea, vomiting, belch, pantothenic acid, noisy and other symptoms caused by gastric mucosa inflammation, erosion and ulcer. Has good repairing, inhibiting and reversing effects on gastric ulcer and duodenal ulcer which are already developed to the stages of gastrorrhagia, gastric perforation, pyloric obstruction and even canceration. The invention relates to a traditional Chinese medicine granule formula for treating gastric ulcer and duodenal ulcer and a preparation method thereof, which belong to pure traditional Chinese medicine preparations, and have the characteristics of reasonable formula, convenient administration, good effect through clinical verification for many years and treatment of both symptoms and root causes.
Description
Technical Field
The invention is directed to the technical development field of chronic gastric ulcer and duodenal ulcer treatment.
The invention is specifically directed to a traditional Chinese medicine granule preparation for treating gastrointestinal mucosa inflammation and ulcer surface and carrying out medicine restoration. The invention particularly relates to a traditional Chinese medicine granule which is used as a raw material and has good regulating and curing effects on symptoms such as gastric cavity pain, fullness, nausea, vomiting, eructation, pantothenic acid, noisy and the like caused by deficiency of the primary and secondary aspects of the invention, deficiency of both qi and yin, and gastric collaterals blood stasis to cause gastric mucosal inflammation, erosion and ulcer by taking a formula thought of 'flat ulcer' of activating blood circulation to remove blood stasis, dredging collaterals to relieve pain, regulating qi and blood and promoting swelling and promoting granulation.
Chronic gastric ulcer and duodenal ulcer belong to frequently-occurring diseases of clinical common diseases, and the treatment of the chronic gastric ulcer, the duodenal ulcer, the spleen and the stomach, the monarch, the minister, the assistant and the guide are taken together, so that the key of curing is realized. The invention combines the temporary evidence summary, dialectical addition and subtraction, and ensures that the granule formula for treating chronic gastric ulcer and duodenal ulcer is more perfect and reasonable, and has good effect in clinical practical medication for many years.
The invention also relates to a patent formula and a preparation process.
Background
The invention has outstanding medication characteristics of activating blood circulation to dissipate blood stasis, dredging collaterals to relieve pain, regulating qi and blood, detumescence and promoting granulation, and has good treatment effects on symptoms such as gastralgia, fullness, nausea, vomiting, eructation, pantothenic acid, noisy and the like caused by gastric mucosa inflammation, erosion and ulcer. Has good repairing, inhibiting and reversing effects on gastric ulcer and duodenal ulcer which are already developed to the stages of gastrorrhagia, gastric perforation, pyloric obstruction and even canceration.
The invention aims at the aim of pursuing the curative effect by pursuing pure medicinal materials of traditional Chinese medicine particles and advanced extraction and preparation process, and develops a traditional Chinese medicine particle formula for treating gastric ulcer and duodenal ulcer, and has good regulating effect on symptoms such as gastralgia, fullness, nausea, vomiting, eructation, pantothenic acid, noisy and the like caused by deficiency of the principal and secondary aspect of the invention, deficiency of both qi and yin, and gastric collaterals blood stasis to cause gastric mucosal inflammation, erosion and ulcer. Has good repairing, inhibiting and reversing effects on gastric ulcer and duodenal ulcer which are already developed to the stages of gastrorrhagia, gastric perforation, pyloric obstruction and even canceration.
The Shi traditional Chinese medicine and Shijia with the qualification of traditional Chinese medicine particle extraction and preparation develop deep business cooperation with the Kaolin pharmaceutical company and Shijia Shenwei pharmaceutical group company, and the two companies directly supply the traditional Chinese medicine of 'single-component particles' prepared by the high-tech traditional Chinese medicine extraction technology to Beijing Shi traditional Chinese medicine pharmacy as required, and the 'Hengan HM-5G' high-tech computer is used for professionally preparing a traditional Chinese medicine particle patent formula for treating gastric ulcer and duodenal ulcer, so that the traditional Chinese medicine particle formula is used for patients with chronic gastric diseases.
Disclosure of Invention
The invention aims to provide a compound prepared from pure traditional Chinese medicine particles for treating chronic gastric diseases such as gastric ulcer, duodenal ulcer and the like. The formula has the functions of promoting blood circulation, removing blood stasis, promoting circulation of qi, relieving pain, eliminating stagnation, regulating qi and blood, relieving swelling and promoting granulation, and has good regulating and treating effects on symptoms such as gastralgia, fullness, nausea, emesis, eructation, pantothenic acid, noisy and the like caused by deficiency of the principal and secondary aspect of disease, deficiency of both qi and yin, and gastric collaterals blood stasis. Has good repairing, inhibiting and reversing effects on gastric ulcer and duodenal ulcer which are already developed to the stages of gastrorrhagia, gastric perforation, pyloric obstruction and even canceration.
The invention is characterized by comprising ginseng, vinegar corydalis tuber, pseudo-ginseng, fructus amomi, safflower, bletilla striata, dandelion, radix bupleuri, fructus aurantii, liquorice, radix curcumae, dried orange peel, angelica sinensis, radix sileris, white peony root, malt, medicated leaven and hawthorn, wherein the weight ratio range of each component is as follows:
1/15 to 1/20 of ginseng. 1/15 to 1/20 of vinegar corydalis tuber. 1/15 to 1/20 of notoginseng.
Fructus Amomi 1/15-1/20. 1/15 to 1/20 of safflower. 1/15 to 1/20 of bletilla striata.
1/15 to 1/20 of dandelion. 1/15 to 1/20 of bupleurum root. 1/15 to 1/20 of fructus aurantii.
1/15 to 1/20 of licorice. 1/15 to 1/20 of radix curcumae. 1/15 to 1/20 of dried orange peel.
1/15 to 1/20 of angelica. 1/15 to 1/20 of the wind resistance. White peony root 1/15-1/20.
1/15 to 1/20 of the malt. 1/15 to 1/20 of the medicated leaven. 1/15 to 1/20 of the scorched hawthorn fruit.
In the formula of the invention, the following description is made on the characteristic, taste, channel tropism and efficacy of single granule components in the ingredient formula:
ginseng: warm nature, sweet and slightly bitter. Enter spleen meridian and lung meridian. Efficacy: tonifying qi and deficiency, invigorating spleen and lung, promoting fluid production and quenching thirst, and treating weakness of spleen and stomach, anorexia, loose stool, listlessness, weakness, emesis, diarrhea, lung qi deficiency, cough and asthma due to movement, spontaneous sweat and pulse deficiency, susceptibility to wind cold, qi and yin deficiency, etc.
Vinegar rhizoma corydalis (vinegar processed): pungent and bitter in flavor, warm in nature, enter liver and spleen meridians. Efficacy: promoting blood circulation, activating qi-flowing, and relieving pain, and can be used for treating chest pain, liver and stomach pain, dysmenorrhea, and abdominal pain due to blood stasis.
Pseudo-ginseng: sweet and slightly bitter in flavor and warm in nature. Enter liver meridian and stomach meridian. Efficacy: removing blood stasis, stopping bleeding, detumescence and relieving pain. Thoracoabdominal pain, traumatic swelling and pain.
Fructus Amomi: pungent and warm. Enter spleen and stomach meridians. Resolving dampness, promoting qi circulation, warming middle energizer and preventing abortion. Efficacy: for abdominal distention and pain, anorexia, vomiting and diarrhea due to damp obstruction of middle energizer and qi stagnation of spleen and stomach.
Safflower: promote menstruation and activate blood. Pungent, warm and nontoxic in nature. It enters heart meridian, liver meridian and kidney meridian. Efficacy: promoting blood circulation, dredging channels, removing blood stasis and relieving pain. For pain due to blood stasis, carbuncle, swelling and traumatic injury.
Bletilla striata: slightly cold, bitter, sweet and astringent; lung meridian, liver meridian and stomach meridian. Efficacy: astringing to stop bleeding, detumescence and promoting granulation. Can be used for treating gastric ulcer, duodenal ulcer, hemorrhage, and gastric mucosa.
Has protective effect on lung and liver injury.
Dandelion: bitter in flavor, sweet in flavor, cold in nature, enter liver and stomach meridians. Efficacy: clearing heat, detumescence, promoting urination and detoxicating. Can be used for treating gastroenteropathy, acute gastroenteritis, gastritis, tonsillitis, parotitis, and urinary tract infection; has good effects of promoting bile flow, protecting liver and resisting ulcer.
Bupleurum root: pungent, bitter and slightly cold. It enters liver meridian, gallbladder meridian and lung meridian. Efficacy: has the effects of relieving exterior syndrome and fever, soothing liver and relieving depression, and the like, and has the effects of inhibiting gastric acid secretion, resisting ulcer, and the like in modern pharmacological research.
Fructus Aurantii: bitter, pungent and sour properties enter spleen meridian and stomach meridian. Efficacy: qi regulating, middle energizer relieving, chest and hypochondrium qi stagnation, distending pain, indigestion, visceral organ prolapse and antiulcer.
Licorice root: sweet in flavor, neutral in nature, enters heart, lung, spleen and stomach meridians. Efficacy: invigorating spleen, replenishing qi, eliminating phlegm, relieving cough, clearing heat, detoxicating, relieving spasm, relieving pain, and harmonizing the medicines.
Radix Curcumae: pungent, bitter and cold. It enters liver meridian, heart meridian and lung meridian. Efficacy: promoting blood circulation, relieving pain, promoting qi circulation, resolving stagnation, clearing away heart-fire, cooling blood, promoting bile flow, and eliminating jaundice. Can be used for treating chest and hypochondrium pain, chest pain, amenorrhea dysmenorrhea, breast pain, fever unconsciousness, epilepsia, hematemesis, epistaxis, jaundice, and dark urine.
Dried orange peel: bitter and pungent in flavor and warm in nature. Enter lung meridian and spleen meridian. Efficacy: regulate qi, invigorate spleen, dry dampness and resolve phlegm. Can be used for treating abdominal distention, anorexia, vomiting and diarrhea, cough with excessive phlegm.
Chinese angelica root: sweet and pungent in flavor and warm in nature. It enters liver, heart and spleen meridians. Efficacy: replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation. Blood deficiency, sallow complexion, deficiency-cold abdominal pain, dizziness and palpitation.
Wind prevention: pungent and slightly sweet, and slightly warm. It enters bladder meridian, lung meridian, spleen meridian and liver meridian. Efficacy: dispelling wind, relieving exterior syndrome, relieving spasm, relieving pain, relieving diarrhea, and relieving itching.
White peony root: sweet and pungent in nature and warm in nature. Enter liver meridian and spleen meridian. Efficacy: nourishing blood, regulating menstruation, softening liver, relieving pain, astringing yin, suppressing sweating, and suppressing liver yang.
Malt preparation: sweet and flat in taste, enters spleen and stomach meridians; the efficacy of resolving food stagnation, dyspepsia, abdominal distention and the like, mainly resolving wheaten food, and the stir-baked malt has the efficacy of promoting lactation.
Burnt medicated leaven: massa Medicata Fermentata is warm in nature and enters spleen meridian and stomach meridian. Efficacy: promoting digestion, resolving food stagnation, strengthening spleen and stomach; can be used for treating dyspepsia, abdominal distention, and anorexia; can be used for treating chronic gastritis, atrophic gastritis, acute gastroenteritis, dysentery, abdominal distention, abdominal pain, diarrhea, anorexia, dyspepsia, etc.
And (3) burnt hawthorn: sour and sweet, slightly warm, enter spleen meridian, stomach meridian and liver meridian; efficacy: it has effects in promoting digestion, removing food stagnation, promoting blood circulation, and dispelling blood stasis, and can be used for treating abdominal distention, abdominal pain, dysentery, etc.
Claims (3)
1. The invention relates to a traditional Chinese medicine granule formula for treating gastric ulcer and duodenal ulcer and a preparation method thereof, which are characterized in that: the formula comprises the following components: ginseng, vinegar-processed corydalis tuber, pseudo-ginseng, fructus amomi, safflower, bletilla striata, dandelion, radix bupleuri, fructus aurantii, liquorice, radix curcumae, dried orange peel, angelica sinensis, radix sileris, white paeony root, roasted malt, roasted medicated leaven and roasted hawthorn. The weight ratio of the components is as follows:
1/15 to 1/20 of ginseng. 1/15 to 1/20 of vinegar corydalis tuber. 1/15 to 1/20 of notoginseng.
Fructus Amomi 1/15-1/20. 1/15 to 1/20 of safflower. 1/15 to 1/20 of bletilla striata.
1/15 to 1/20 of dandelion. 1/15 to 1/20 of bupleurum root. 1/15 to 1/20 of fructus aurantii.
1/15 to 1/20 of licorice. 1/15 to 1/20 of radix curcumae. 1/15 to 1/20 of dried orange peel.
1/15 to 1/20 of angelica. 1/15 to 1/20 of the wind resistance. White peony root 1/15-1/20.
1/15 to 1/20 of the malt. 1/15 to 1/20 of the medicated leaven. 1/15 to 1/20 of the scorched hawthorn fruit.
2. The invention relates to a Chinese medicinal granule formulation for treating gastric ulcer and duodenal ulcer and a preparation method thereof, which is characterized in that the formulation is quantitatively prepared, single Chinese medicinal granules which are independently packaged and provided by Shijia and Shijia Shenwei pharmaceutical company, are directly supplied to a Beijing Chinese medical clinic pharmacy, the single granule dosage of the formulation is set in a high-tech computer of Hengan HM-5G according to the quantitative requirement of the formulation of the Weianping ulcer granules, when an HM-5G Chinese medicinal granule formulation machine operates, the computer can brake to perform formulation and mixing according to the set proportion, the mixed formulation granules are automatically filled into packaging bags which are filled into machines in advance, each packaging bag is the once dosage, and the filled Weianping ulcer granules are ready for use.
3. The method of formulating a formulation as claimed in claim 2, wherein; the preparation method further comprises the step of taking the prepared traditional Chinese medicine particles according to the doctor's advice.
Priority Applications (1)
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