CN117120616A - 具有羧酸还原活性的重组多肽 - Google Patents

具有羧酸还原活性的重组多肽 Download PDF

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Publication number
CN117120616A
CN117120616A CN202280025099.3A CN202280025099A CN117120616A CN 117120616 A CN117120616 A CN 117120616A CN 202280025099 A CN202280025099 A CN 202280025099A CN 117120616 A CN117120616 A CN 117120616A
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CN
China
Prior art keywords
leu
ala
amino acid
val
gly
Prior art date
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Pending
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CN202280025099.3A
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English (en)
Chinese (zh)
Inventor
井阪光二
宫武令
片山沙绫香
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Asahi Kasei Corp
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Asahi Kasei Corp
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Publication of CN117120616A publication Critical patent/CN117120616A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0103—Aryl-aldehyde dehydrogenase (NADP+) (1.2.1.30)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202280025099.3A 2021-03-30 2022-03-11 具有羧酸还原活性的重组多肽 Pending CN117120616A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021057308 2021-03-30
JP2021-057308 2021-03-30
PCT/JP2022/010912 WO2022209763A1 (ja) 2021-03-30 2022-03-11 カルボン酸還元活性を有する組換えポリペプチド

Publications (1)

Publication Number Publication Date
CN117120616A true CN117120616A (zh) 2023-11-24

Family

ID=83456178

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280025099.3A Pending CN117120616A (zh) 2021-03-30 2022-03-11 具有羧酸还原活性的重组多肽

Country Status (6)

Country Link
US (1) US20250019671A1 (https=)
EP (1) EP4317437A4 (https=)
JP (1) JPWO2022209763A1 (https=)
KR (1) KR20230160398A (https=)
CN (1) CN117120616A (https=)
WO (1) WO2022209763A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3166910A1 (fr) * 2024-10-02 2026-04-03 Compagnie Generale Des Etablissements Michelin Utilisation d’une carboxylase reductase bacterienne pour produire du terephthalaldehyde

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573931A (en) 1995-08-28 1996-11-12 Michigan Biotechnology Institute Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants
EP2427544B1 (en) 2009-05-07 2019-07-17 Genomatica, Inc. Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid
JP2011254747A (ja) 2010-06-08 2011-12-22 Toyota Central R&D Labs Inc 高級アルコール生産微生物及びその利用
JP2012177721A (ja) 2011-02-25 2012-09-13 Konica Minolta Business Technologies Inc 画像形成装置
WO2012177721A1 (en) 2011-06-22 2012-12-27 Genomatica, Inc. Microorganisms for producing 6-aminocaproic acid
BR122019026987B1 (pt) 2012-04-02 2022-01-18 Genomatica, Inc Polipeptídeo variante da ácido carboxílico redutase (car), célula hospedeira recombinante, cultura de células e método de produzir uma composição de álcool graxo com alto título, rendimento ou produtividade
EP2746400A1 (de) 2012-12-21 2014-06-25 Evonik Industries AG Herstellung von Aminen und Diaminen aus einer Carbonsäure oder Dicarbonsäure oder eines Monoesters davon
WO2015042201A2 (en) 2013-09-17 2015-03-26 Zymochem Inc. A high yield route for the production of compounds from renewable sources
WO2015085271A1 (en) 2013-12-05 2015-06-11 REG Life Sciences, LLC Microbial production of fatty amines
WO2016077800A1 (en) 2014-11-14 2016-05-19 Invista North America S.á.r.l. Methods and materials for producing 6-carbon monomers
CA2897454C (en) 2015-07-03 2023-03-14 Governing Council Of The University Of Toronto Microorganisms and methods for biosynthesis of adipic acid
EP4317416A4 (en) * 2021-03-30 2025-06-25 Asahi Kasei Kabushiki Kaisha Recombinant microorganism and method for producing a C6 compound

Also Published As

Publication number Publication date
KR20230160398A (ko) 2023-11-23
EP4317437A4 (en) 2024-11-20
JPWO2022209763A1 (https=) 2022-10-06
EP4317437A1 (en) 2024-02-07
WO2022209763A1 (ja) 2022-10-06
US20250019671A1 (en) 2025-01-16

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