CN116997782A - 用于检测生物制药产品的装配连接处的可能的气体泄漏的密封装置和方法 - Google Patents

用于检测生物制药产品的装配连接处的可能的气体泄漏的密封装置和方法 Download PDF

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Publication number
CN116997782A
CN116997782A CN202280017191.5A CN202280017191A CN116997782A CN 116997782 A CN116997782 A CN 116997782A CN 202280017191 A CN202280017191 A CN 202280017191A CN 116997782 A CN116997782 A CN 116997782A
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CN
China
Prior art keywords
housing unit
gas
sealing arrangement
annular
fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280017191.5A
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English (en)
Chinese (zh)
Inventor
沙米尔·法特拉齐
迈克尔·布朗
弗雷德里克·巴赞
弗洛里安·布莱克
尼古拉斯·戴维宁
马可·霍格维
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sartorius Stedim FMT SAS
Original Assignee
Sartorius Stedim FMT SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sartorius Stedim FMT SAS filed Critical Sartorius Stedim FMT SAS
Publication of CN116997782A publication Critical patent/CN116997782A/zh
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00—Investigating fluid-tightness of structures
    • G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/04—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
    • G01M3/20—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material
    • G01M3/22—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators
    • G01M3/226—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators for containers, e.g. radiators
    • G01M3/227—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators for containers, e.g. radiators for flexible or elastic containers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00—Investigating fluid-tightness of structures
    • G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/04—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
    • G01M3/20—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material
    • G01M3/22—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators
    • G01M3/223—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators for pipe joints or seals
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16J—PISTONS; CYLINDERS; SEALINGS
    • F16J15/00—Sealings
    • F16J15/02—Sealings between relatively-stationary surfaces
    • F16J15/021—Sealings between relatively-stationary surfaces with elastic packing
    • F16J15/022—Sealings between relatively-stationary surfaces with elastic packing characterised by structure or material
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16J—PISTONS; CYLINDERS; SEALINGS
    • F16J15/00—Sealings
    • F16J15/02—Sealings between relatively-stationary surfaces
    • F16J15/06—Sealings between relatively-stationary surfaces with solid packing compressed between sealing surfaces
    • F16J15/062—Sealings between relatively-stationary surfaces with solid packing compressed between sealing surfaces characterised by the geometry of the seat
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L23/00—Flanged joints
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L33/00—Arrangements for connecting hoses to rigid members; Rigid hose-connectors, i.e. single members engaging both hoses
    • F16L33/30—Arrangements for connecting hoses to rigid members; Rigid hose-connectors, i.e. single members engaging both hoses comprising parts inside the hoses only
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L55/00—Devices or appurtenances for use in, or in connection with, pipes or pipe systems
    • F16L55/18—Appliances for use in repairing pipes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00—Investigating fluid-tightness of structures
    • G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/04—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
    • G01M3/20—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material
    • G01M3/22—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators
    • G01M3/226—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators for containers, e.g. radiators
    • G01M3/229—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators for containers, e.g. radiators removably mounted in a test cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0004—Gaseous mixtures, e.g. polluted air
    • G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L33/00—Arrangements for connecting hoses to rigid members; Rigid hose-connectors, i.e. single members engaging both hoses
    • F16L33/02—Hose-clips

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Combustion & Propulsion (AREA)
  • Geometry (AREA)
  • Examining Or Testing Airtightness (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CN202280017191.5A 2021-04-19 2022-04-14 用于检测生物制药产品的装配连接处的可能的气体泄漏的密封装置和方法 Pending CN116997782A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21169252.0 2021-04-19
EP21169252.0A EP4080183B1 (en) 2021-04-19 2021-04-19 Sealing device and method for detecting a possible gas leak at a fitting connection for biopharmaceutical product
PCT/EP2022/060143 WO2022223476A1 (en) 2021-04-19 2022-04-14 Sealing device and method for detecting a possible gas leak at a fitting connection for biopharmaceutical product

Publications (1)

Publication Number Publication Date
CN116997782A true CN116997782A (zh) 2023-11-03

Family

ID=75588079

Family Applications (1)

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CN202280017191.5A Pending CN116997782A (zh) 2021-04-19 2022-04-14 用于检测生物制药产品的装配连接处的可能的气体泄漏的密封装置和方法

Country Status (5)

Country Link
US (1) US12050156B2 (cg-RX-API-DMAC7.html)
EP (1) EP4080183B1 (cg-RX-API-DMAC7.html)
JP (1) JP2024515185A (cg-RX-API-DMAC7.html)
CN (1) CN116997782A (cg-RX-API-DMAC7.html)
WO (1) WO2022223476A1 (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116593098B (zh) * 2023-07-17 2023-09-15 山东科锐医疗用品有限公司 一种输液器导管的测气检测装置及其使用方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5799830A (en) * 1996-11-08 1998-09-01 Carroll; David C. Pressure vessel access port
CN101105262A (zh) * 2006-07-14 2008-01-16 固特异轮胎和橡胶公司 用于双胎体软管的泄漏检测系统和方法
CN101151514A (zh) * 2005-02-28 2008-03-26 高级技术材料公司 用于流体分配容器的泄漏测试和鉴定的设备及方法
US20100298738A1 (en) * 2009-05-13 2010-11-25 Felts John T Vessel, coating, inspection and processing apparatus
CN107407614A (zh) * 2015-03-10 2017-11-28 爱德华兹生命科学公司 手术管道泄漏测试
CN110261276A (zh) * 2014-04-23 2019-09-20 迈克尔·T·贝尔德 测试具有过滤器盖的水过滤筒的方法以及组件

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19935293A1 (de) * 1999-07-27 2001-02-01 Leybold Vakuum Gmbh Folienlecksuchkammer
JP2005055263A (ja) * 2003-08-01 2005-03-03 Ts:Kk リークガス検出装置
US8448498B1 (en) * 2010-08-27 2013-05-28 United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Hermetic seal leak detection apparatus
US9097609B1 (en) * 2013-04-30 2015-08-04 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Hermetic seal leak detection apparatus with variable size test chamber
US9530904B2 (en) * 2014-09-24 2016-12-27 General Electric Company High temerature, hermetically sealed, triaxial mount for a light sensitive element
FR3079301B1 (fr) * 2018-03-21 2020-10-30 Gaztransport Et Technigaz Procede de diffusion d'un gaz traceur et procede de test de l'etancheite d'une membrane
FR3096458B1 (fr) * 2019-05-21 2021-04-23 Gaztransport Et Technigaz Dispositif de détection de fuite
EP3757538B1 (en) * 2019-06-26 2023-06-14 Sartorius Stedim Fmt Sas System and method for detecting a possible loss of integrity of a flexible bag for biopharmaceutical product

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5799830A (en) * 1996-11-08 1998-09-01 Carroll; David C. Pressure vessel access port
CN101151514A (zh) * 2005-02-28 2008-03-26 高级技术材料公司 用于流体分配容器的泄漏测试和鉴定的设备及方法
CN101105262A (zh) * 2006-07-14 2008-01-16 固特异轮胎和橡胶公司 用于双胎体软管的泄漏检测系统和方法
US20100298738A1 (en) * 2009-05-13 2010-11-25 Felts John T Vessel, coating, inspection and processing apparatus
CN110261276A (zh) * 2014-04-23 2019-09-20 迈克尔·T·贝尔德 测试具有过滤器盖的水过滤筒的方法以及组件
CN107407614A (zh) * 2015-03-10 2017-11-28 爱德华兹生命科学公司 手术管道泄漏测试

Also Published As

Publication number Publication date
WO2022223476A1 (en) 2022-10-27
EP4080183A1 (en) 2022-10-26
JP2024515185A (ja) 2024-04-05
US12050156B2 (en) 2024-07-30
EP4080183B1 (en) 2023-10-25
US20240192078A1 (en) 2024-06-13

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PB01 Publication
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SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information
CB02 Change of applicant information

Country or region after: France

Address after: Palud Industrial Zone, Rue du Rh o ne, Aubonne, France

Applicant after: Sadolis Stedt Biotechnology

Address before: Aubagne

Applicant before: SARTORIUS STEDIM FMT S.A.S.

Country or region before: France

CB02 Change of applicant information
CB02 Change of applicant information

Country or region after: France

Address after: Aubagne

Applicant after: Sadolis Standim FMT

Address before: Palud Industrial Zone, Rue du Rh o ne, Aubonne, France

Applicant before: Sadolis Stedt Biotechnology

Country or region before: France