CN116897201A - 用于扩增调节性t细胞的方法 - Google Patents

用于扩增调节性t细胞的方法 Download PDF

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Publication number
CN116897201A
CN116897201A CN202280016734.1A CN202280016734A CN116897201A CN 116897201 A CN116897201 A CN 116897201A CN 202280016734 A CN202280016734 A CN 202280016734A CN 116897201 A CN116897201 A CN 116897201A
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tregs
population
aspects
cells
resting
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CN202280016734.1A
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Chinese (zh)
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约翰·赵
凯雷姆·乔纳坦·通塞尔
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Ksq Treatment Co
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Ksq Treatment Co
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0637—Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N2501/50—Cell markers; Cell surface determinants
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CN202280016734.1A 2021-02-23 2022-02-23 用于扩增调节性t细胞的方法 Pending CN116897201A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163152787P 2021-02-23 2021-02-23
US63/152,787 2021-02-23
PCT/US2022/017526 WO2022182763A1 (en) 2021-02-23 2022-02-23 Methods for expanding regulatory t cells

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Publication Number Publication Date
CN116897201A true CN116897201A (zh) 2023-10-17

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US (1) US20240228962A9 (enExample)
EP (1) EP4297757A4 (enExample)
JP (1) JP2024507373A (enExample)
CN (1) CN116897201A (enExample)
AU (1) AU2022226163A1 (enExample)
CA (1) CA3206049A1 (enExample)
WO (1) WO2022182763A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024243552A1 (en) * 2023-05-25 2024-11-28 Board Of Regents, The University Of Texas System Methods using st2 to identify patients for cancer therapy
WO2025096685A1 (en) * 2023-10-30 2025-05-08 City Of Hope Methods of making and using regulatory t cells for treatment of autoimmune disorders and cancers

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007538000A (ja) * 2004-01-08 2007-12-27 リージエンツ・オブ・ザ・ユニバーシテイ・オブ・カリフオルニア 制御性ｔ細胞は自己免疫を抑制する
WO2011126806A1 (en) * 2010-04-08 2011-10-13 The Trustees Of The University Of Pennsylvania Methods to expand a t regulatory cell master cell bank
US9018006B2 (en) * 2010-07-23 2015-04-28 The University Of Toledo Stable Tregs and related materials and methods
WO2013131045A1 (en) * 2012-03-02 2013-09-06 The Regents Of The University Of California Expansion of alloantigen-reactive regulatory t cells
WO2014183056A1 (en) * 2013-05-10 2014-11-13 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Design and use of specific regulatory t-cells to induce immune tolerance
EP3551749B1 (en) * 2016-12-07 2023-09-27 East Carolina University Compositions and methods for in vitro cultivation and/or expansion of regulatory t cells
EP3571294A1 (en) * 2017-01-18 2019-11-27 F1 Oncology, Inc. Methods of transducing and expanding immune cells and uses thereof
CN110678190A (zh) * 2017-03-28 2020-01-10 宾夕法尼亚大学董事会 保护移植的组织免受排斥的方法
US10842815B2 (en) * 2017-06-16 2020-11-24 Stemspine Llc Perispinal perfusion by administration of T regulatory cells alone or in combination with angiogenic cell therapies
EP3716988A4 (en) * 2017-11-29 2021-12-15 Figene, LLC INTERACTION OF FIBROBLASTS AND IMMUNE CELLS FOR THE ACTIVATION AND USE THEREOF
JP2021524233A (ja) * 2018-05-17 2021-09-13 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 薬物耐性免疫細胞及びその用途
JP7642548B2 (ja) * 2019-02-01 2025-03-10 ケーエスキュー セラピューティクス， インコーポレイテッド 免疫療法の改善のための遺伝子調節組成物及び遺伝子調節方法

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EP4297757A4 (en) 2025-02-26
US20240228962A9 (en) 2024-07-11
AU2022226163A1 (en) 2023-09-28
EP4297757A1 (en) 2024-01-03
AU2022226163A9 (en) 2024-01-18
US20240132843A1 (en) 2024-04-25
WO2022182763A1 (en) 2022-09-01
CA3206049A1 (en) 2022-09-01
JP2024507373A (ja) 2024-02-19

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