JP2025504392A5 - - Google Patents

Info

Publication number
JP2025504392A5
JP2025504392A5 JP2024541154A JP2024541154A JP2025504392A5 JP 2025504392 A5 JP2025504392 A5 JP 2025504392A5 JP 2024541154 A JP2024541154 A JP 2024541154A JP 2024541154 A JP2024541154 A JP 2024541154A JP 2025504392 A5 JP2025504392 A5 JP 2025504392A5
Authority
JP
Japan
Prior art keywords
cells
molecules
modified
cell
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024541154A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025504392A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/060341 external-priority patent/WO2023133568A2/en
Publication of JP2025504392A publication Critical patent/JP2025504392A/ja
Publication of JP2025504392A5 publication Critical patent/JP2025504392A5/ja
Pending legal-status Critical Current

Links

JP2024541154A 2022-01-10 2023-01-09 多能性幹細胞から分化した低免疫性β細胞ならびに関連する使用及び方法 Pending JP2025504392A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202263298214P 2022-01-10 2022-01-10
US63/298,214 2022-01-10
US202263320691P 2022-03-16 2022-03-16
US63/320,691 2022-03-16
US202263322208P 2022-03-21 2022-03-21
US63/322,208 2022-03-21
US202263352605P 2022-06-15 2022-06-15
US63/352,605 2022-06-15
US202263353534P 2022-06-17 2022-06-17
US63/353,534 2022-06-17
PCT/US2023/060341 WO2023133568A2 (en) 2022-01-10 2023-01-09 Hypoimmune beta cells differentiated from pluripotent stem cells and related uses and methods

Publications (2)

Publication Number Publication Date
JP2025504392A JP2025504392A (ja) 2025-02-12
JP2025504392A5 true JP2025504392A5 (enExample) 2026-01-19

Family

ID=87074351

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024541154A Pending JP2025504392A (ja) 2022-01-10 2023-01-09 多能性幹細胞から分化した低免疫性β細胞ならびに関連する使用及び方法

Country Status (9)

Country Link
US (1) US20250223564A1 (enExample)
EP (1) EP4463171A4 (enExample)
JP (1) JP2025504392A (enExample)
KR (1) KR20240142624A (enExample)
AU (1) AU2023204829A1 (enExample)
CA (1) CA3246902A1 (enExample)
IL (1) IL314029A (enExample)
MX (1) MX2024008571A (enExample)
WO (1) WO2023133568A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024218715A1 (en) 2023-04-19 2024-10-24 Btl Healthcare Technologies A.S. Culture media based on protein hydrolysate and a process for preparing thereof
CN121843705A (zh) * 2023-05-03 2026-04-10 萨那生物科技公司 工程化胰岛细胞的给药和施用方法
IL325954A (en) * 2023-07-28 2026-03-01 Vertex Pharma Cell therapy for diabetes
CN116732099B (zh) * 2023-08-07 2023-11-24 北赛泓升(北京)生物科技有限公司 一种干细胞多重CRISPR/Cas基因组编辑方法
US12668774B2 (en) 2023-10-12 2026-06-30 Btl Healthcare Technologies A.S. Product, system and method of cell cultivation
IL328729A (en) 2023-12-01 2026-07-01 Sigilon Therapeutics Inc Methods for producing stem cell-derived islet-like cells, as well as populations and compositions comprising them
WO2025212859A1 (en) * 2024-04-03 2025-10-09 Solid Biosciences, Inc. Methods and constructs for increasing solid organ transplant survival

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3344758T (pt) * 2015-09-01 2021-10-28 Ncardia B V Um método in vitro para diferenciação de uma população de células estaminais pluripotentes humanas numa população de células de cardiomiócitos
KR20240095477A (ko) * 2017-01-13 2024-06-25 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 면역조작된 만능 세포
EP3824075A4 (en) * 2018-07-17 2022-04-20 The Regents of The University of California CHIMERA ANTIGEN RECEPTOR T-CELLS DERIVED FROM IMMUNOMANIPULATED PLURIPOTENTS STEM CELLS
AU2019305585A1 (en) * 2018-07-17 2021-01-28 The Regents Of The University Of California Cells differentiated from immunoengineered pluripotent cells
IL297636A (en) * 2020-04-27 2022-12-01 Sana Biotechnology Inc Repeat dosing of hypoimmunogenic cells

Similar Documents

Publication Publication Date Title
JP2021518161A (ja) 免疫療法の改善のための遺伝子調節組成物及び遺伝子調節方法
WO2020057666A1 (zh) 表达有嵌合受体的t细胞
JP2022543112A (ja) Dux4発現細胞およびそれらの使用
JP2021518162A (ja) 免疫療法の改善のための遺伝子調節組成物及び遺伝子調節方法
JP2021518160A (ja) 免疫療法の改善のための遺伝子調節組成物及び遺伝子調節方法
US20250223564A1 (en) Hypoimmune beta cells differentiated from pluripotent stem cells and related uses and methods
TW202302841A (zh) 用於調變car-t活性之方法與組成物
US12448437B2 (en) Transplant tolerance induction with carbodiimide treated tolerizing vaccine
TW202202155A (zh) 用於治療神經病症及病況之低免疫原性神經細胞
KR20240137574A (ko) 자가면역 질환 치료를 위한 키메라 항원 수용체[chimeric antigen receptor, car] t 세포 및 관련 방법
JP2024503291A (ja) ユニバーサルドナー細胞
EP4090338A1 (en) T-cell death associated gene 8 (tdag8) modulation to enhance cellular cancer therapies
US20250186493A1 (en) Artificial antigen-specific immunoregulatory t (airt) cells
Maffini et al. The prevention of disease relapse after allogeneic hematopoietic cell transplantation in acute myeloid leukemia
US20240132843A1 (en) Methods for expanding regulatory t cells
CA3174673A1 (en) Monoamine oxidase inhibitors as modifiers of beta cell vulnerability in type 1 diabetes
US20260048086A1 (en) Methods of dosing and administration of engineered islet cells
WO2026059868A2 (en) Immunosuppression resistant t cells for post-transplant disorders
JP2024534003A (ja) 細胞ベースの治療法に向けた細胞の操作、ならびに関連する組成物及び方法
Darden Regulation of Islet Cell Differentiation and Function by Calcineurin/NFATc2 Signaling and Applications for Islet Cell Transplantation
HK40061122A (en) Transplant tolerance induction with carbodiimide treated tolerizing vaccine
IL300524A (en) Allogeneic reactive immune cell exclusion device and its uses for protecting cells from a donor source from allogeneic rejection