CN116869899A - Skin-care degerming washing-free gel and preparation method thereof - Google Patents
Skin-care degerming washing-free gel and preparation method thereof Download PDFInfo
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- CN116869899A CN116869899A CN202311028372.0A CN202311028372A CN116869899A CN 116869899 A CN116869899 A CN 116869899A CN 202311028372 A CN202311028372 A CN 202311028372A CN 116869899 A CN116869899 A CN 116869899A
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- skin
- skin care
- humectant
- extract
- washing
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Abstract
The application relates to the technical field of daily chemical products, and particularly discloses skin-care degerming washing-free gel and a preparation method thereof. The skin-care degerming washing-free gel comprises the following raw materials in percentage by weight: 1-2% of humectant, 0.5-2% of aloe extract, 0.01-0.05% of plant essential oil, 0.04-0.07% of essence, 0.003-0.08% of hypochlorous acid, 0.5-1.5% of trisodium phosphate, 4-6% of sodium metasilicate, 0.1-1% of sodium chloride and the balance of deionized water. The preparation method comprises the following steps: mixing aloe extract and deionized water, adding hypochlorous acid and humectant, mixing, adding plant essential oil and essence, mixing, adding trisodium phosphate and sodium metasilicate, stirring, and adjusting pH to 5-7. The skin-care antibacterial washing-free gel has the advantages of strong antibacterial effect, washing-free effect, moisturizing effect, short volatilizing time, non-sticky hand feeling and good high-temperature and low-temperature stability.
Description
Technical Field
The application relates to the technical field of daily chemical products, in particular to skin-care degerming washing-free gel and a preparation method thereof.
Background
Hand washing has been a major concern in life, and the chances of people getting in public transportation and getting in contact with other people or things have increased greatly from the previous hand washing before meals to the present day, and the chances of disease transmission through hands have increased. The hand cleaning and sterilizing mode also changes from the former soap and perfumed soap to the present hand washing gel, the cleaning effect is better and the use is more convenient.
Besides the advantages of the traditional hand sanitizer, the hand-washing-free gel overcomes the limitation that the traditional hand sanitizer needs to use water, and the ubiquitous bacterial transmission source in daily life threatens the health of people at any time, so that the hand-washing-free gel is a very important problem, and is inconvenient to wash hands in many occasions, the awkward problem can be well solved, and the hand-washing-free gel can be applied to hands for natural drying, thereby meeting the hand disinfection requirements, and is particularly suitable for the hand disinfection requirements in water shortage or inconvenient water use occasions such as offices, riding buses and subways, outdoor travel, and the like.
At present, most of the hand-washing-free gel mainly comprises alcohol, 75% of the alcohol is used as a broad-spectrum disinfectant, the toxicity is low, the sterilization effect is good, the volatilization is rapid, the basic requirement of the hand-washing-free gel can be met, but the high-concentration alcohol is easy to cause hand skin injury, a large amount of water can be taken away when the alcohol volatilizes, the hand skin is dry and can accelerate skin aging, in order to protect the skin, the alcohol concentration is generally reduced, and some skin care components are added, but the alcohol concentration is reduced, so that the sterilization effect is influenced on one hand, and the natural volatilization time of the hand-washing gel is overlong on the other hand, so that a user feels inconvenient.
Disclosure of Invention
In order to ensure the sterilization effect of the hand-washing-free gel, ensure that the skin is free from dry feeling after use, volatilize in a short time and have non-sticky hand feeling, the application provides the skin care degerming washing-free gel and a preparation method thereof.
In a first aspect, the application provides a skin care degerming washing-free gel, which adopts the following technical scheme:
the skin-care degerming washing-free gel comprises the following raw materials in percentage by weight: 1-2% of humectant, 0.5-2% of aloe extract, 0.01-0.05% of plant essential oil, 0.04-0.07% of essence, 0.003-0.08% of hypochlorous acid, 0.5-1.5% of trisodium phosphate, 4-6% of sodium metasilicate, 0.1-1% of sodium chloride and the balance of deionized water.
By adopting the technical scheme, the aloe extract, the humectant, the hypochlorous acid and other raw materials are used for preparing the washing-free gel, wherein alcohol is not added, so that the phenomenon of drying and aging of skin can not be brought away due to volatilization of the alcohol, and the volatilization time is long due to low alcohol concentration, thereby achieving the effects of moistening the skin, moisturizing, quickly volatilizing and being non-sticky; the sodium chloride can keep the hand moist feel, can sterilize and diminish inflammation, and promote skin metabolism; the aloe extract has certain effects on the aspects of moisturizing, diminishing inflammation, inhibiting bacteria, relieving itching, resisting allergy and the like, can improve the fineness of skin, enable the skin of hands to be smooth and elastic, enable moisture to be supplemented after the hands are cleaned by the humectant, seal the moisture in the skin to prevent water and moisture from evaporating, keep the skin elastic and have good skin care effect.
Optionally, the humectant is at least one selected from sodium hyaluronate, propylene glycol, jojoba seed oil, camellia extract, allantoin, tea tree oil, and herba Violae extract.
By adopting the technical scheme, the sodium hyaluronate can supplement water and preserve moisture, so that muscle cells keep activity, accelerate metabolism of skin, increase skin elasticity, promote proliferation and differentiation of epidermal cells, remove oxygen free radicals, form a layer of film on the surface of the skin, generate good smooth feel and lubrication feel, play a role in protecting the skin, and have thickening and stabilizing effects; propylene glycol is fresh and non-sticky, and can absorb moisture from moist air to maintain the moisture content of the skin cuticle; jojoba seed oil contains abundant mineral substances such as vitamin A, vitamin B, calcium, magnesium and the like, has good permeability, is base oil with extremely high stability and good ductility, has chemical molecular arrangement very similar to sebum of human beings, is extremely easy to be classified and absorbed by skin, is suitable for all skin types, has the effects of smoothing pores, regulating grease of oily or mixed skin, moisturizing and moisturizing, increasing skin moisture and preventing aging, and can improve the problems of skin inflammation and sensitivity and the like; the camellia extract can relieve skin allergy symptoms, has the effects of resisting bacteria and diminishing inflammation, and can whiten, delay aging, moisten and moisturize and resist oxidation; allantoin has the physiological functions of promoting tissue growth, cell metabolism, softening horny layer and the like, is a good healing agent for skin wounds, can relieve and treat skin dryness, and enables the skin to be soft and elastic; tea tree oil is colorless or pale yellow liquid, has pleasant cardamon odor, mild property and good skin permeability, does not irritate skin, and can effectively inhibit a plurality of ubiquitous pathogenic bacteria and mold; the pteridopsis japonica flower contains rich anthocyanin, vitamins and other substances, and the pteridopsis japonica flower extract can contain peptides with antibacterial activity, can inhibit escherichia coli, pseudomonas aeruginosa and the like, can delay aging, tighten skin, promote collagen production and increase skin elasticity.
Optionally, the humectant comprises sodium hyaluronate and propylene glycol with a mass ratio of 1 (0.2-0.7).
By adopting the technical scheme, the sodium hyaluronate and the propylene glycol are matched according to the proportion, and the moisturizing agent has a good moisturizing effect.
Optionally, the humectant comprises sodium hyaluronate, propylene glycol, jojoba seed oil and the extract of herba Violae at a mass ratio of 1 (0.2-0.7) (0.2-0.5) (0.1-0.3).
By adopting the technical scheme, the sodium hyaluronate and the propylene glycol can improve the moisture content of skin, supplement water and preserve moisture, jojoba seed oil is similar to sebum, can promote permeation of the no-clean condensation, relieve the dry state of the skin, simultaneously lock moisture, ensure that the sphenoides extract can inhibit bacteria and resist aging, and the four components are matched for use, so that the moisture preservation effect of the no-clean condensation can be effectively improved, the skin is prevented from being dried after being cleaned, and the antibacterial property of the no-clean condensation is increased.
Optionally, the preparation method of the humectant comprises the following steps:
uniformly mixing sodium hyaluronate, propylene glycol, a butterfly bean flower extract, PEG-40 hydrogenated castor oil and caprylic/capric triglyceride to obtain phase A;
mixing jojoba seed oil, glycerol and distilled water, and performing constant temperature water bath at 45-50deg.C for 20-30min to obtain phase B;
adding phase B into phase A, stirring for 20-30min, and homogenizing under 30-35MPa to obtain humectant.
By adopting the technical scheme, under the condition that PEG-40 hydrogenated castor oil is used as an emulsifying agent, a solubilizer and caprylic/capric triglyceride are used as a softening agent and a solvent, uniformly mixing to prepare a phase A, homogenizing jojoba seed oil, glycerol and distilled water to prepare a co-conveying nano carrier, loading various moisturizing components, and co-conveying the nano carrier, so that the multi-target and multi-effect skin care functional components can realize synergistic effect, the moisturizing components penetrate through the stratum corneum, the solubility of indissolvable moisturizing components is improved, and the moisturizing effect is further improved.
Optionally, the sodium hyaluronate comprises isopropyl myristate, sea fennel extract and high molecular weight sodium hyaluronate with molecular weight of 80-150W with mass ratio of (0.1-0.3): (0.5-1): 1.
By adopting the technical scheme, the sea fennel extract is rich in monoterpenes, gamma-terpinenes, thymol methyl ether volatile oil, pectin, vitamins, minerals and the like, can deeply moisten skin, and phenolic acid in the sea fennel extract has better capability of scavenging free radicals and inhibiting the activity of the neuraminidase, so that the whitening effect is achieved; the sodium hyaluronate mainly forms a uniform and breathable water film on the surface layer of skin, so that moisture loss and bacterial infection are effectively prevented, the sodium hyaluronate and the sea fennel extract cooperate to achieve the effects of moisturizing and locking the surface layer and deeply moisturizing, isopropyl myristate can promote the permeation mechanism of the sea fennel extract to mainly act on lipid among cells of the stratum corneum, so that the lipid is structurally changed, the lipid fluidity is increased, the effects of moisturizing and moisturizing the skin are achieved, the absorption of the washing-free gel is promoted, the volatilization of the washing-free gel is accelerated, and the sticky feeling is reduced.
Optionally, the mass ratio of the PEG-40 hydrogenated castor oil, the caprylic/capric triglyceride and the sodium hyaluronate is (0.1-0.3): 0.05-0.1): 1;
the mass ratio of jojoba seed oil, glycerol and distilled water is (0.2-0.5): 0.5-1): 2.
By adopting the technical scheme, the raw materials with the above amounts can be prepared into the co-conveying nano-carrier, and the moisturizing component is loaded on the co-conveying nano-carrier, so that the component synergistic effect is achieved.
Optionally, the skin care degerming washing-free gel also comprises 0.05-0.15% of stabilizer by mass percent.
By adopting the technical scheme, the no-clean condensation is extremely easy to be turbid and hydrated under the low-temperature environment or the high-temperature environment, and has poor stability, so that the stability of the no-clean condensation under the high temperature or the low temperature is improved by adding the stabilizer with a certain proportion into the no-clean condensation.
Optionally, the stabilizer comprises corn sprout extract and hydrolyzed corn cellulose in a mass ratio of 0.5-1:1.
By adopting the technical scheme, the corn sprout extract is a substance rich in adenine derivatives, which is obtained by separating from corn sprouts growing vigorously, the main component is kinetin, the kinetin is an indispensable active substance in animal and plant cells, active oxygen free radicals can be effectively eliminated, oxidative stress damage caused by UVA irradiation is resisted, aging of skin cells caused by oxidization is delayed, the corn sprout extract has good cold resistance, heat resistance and storage performance, surface charge of cellulose particles is increased after corn cellulose crystal hydrolysis, electrostatic repulsion effect and steric hindrance effect among particles are increased, particle aggregation is reduced, therefore, the particle size of hydrolyzed corn cellulose is obviously reduced, after the corn sprout extract is dispersed in a wash-free gel, polar groups are increased due to hydrogen bond breakage obtained among molecular chains after the surface is hydrolyzed, electronegativity is enhanced, after wash-free condensation is added, the surface between liquid drops has relatively anti-aggregation capability, the flocculation phenomenon at low temperature and high temperature is weakened, and the stability is enhanced.
Optionally, the preparation method of the hydrolyzed corn cellulose comprises the following steps: mixing corn cellulose and sulfuric acid solution according to a feed liquid ratio of 1:10-11, hydrolyzing at 45-50deg.C for 1.5-2h, adding distilled water 10 times of the volume of the sulfuric acid solution, mixing, centrifuging, washing to neutrality, lyophilizing, and grinding to obtain powder; preparing the powder into suspension with mass fraction of 0.8-1% with distilled water, ultrasonic dispersing, and homogenizing under 36-40MPa for 5-6min.
By adopting the technical scheme, polar groups are introduced under the hydrolysis of sulfuric acid, and along with the high-pressure homogenization, cellulose is subjected to various forces including impact force and shearing force among particles, cavitation force generated by extreme change of the flow velocity of objects and the like, so that a part of crystalline region and an amorphous region of the cellulose are broken, the particle size is reduced, the particle size distribution is more uniform, part of structures are destroyed, the surface is rough, a loose and porous structure exposes more active groups, the polymerization degree is reduced, the polarity is enhanced, the electronegativity is increased, the capability of relatively resisting aggregation among liquid drops is shown, the liquid drop dispersibility is good, and the flocculation phenomenon is gradually weakened; after high-pressure homogenization, the hydrophilicity of cellulose is improved, and the low-temperature stability of emulsion is improved.
Optionally, the plant essential oil is at least one selected from rose essential oil, chrysanthemum essential oil, tea tree essential oil and peppermint essential oil;
the essence is at least one selected from Gulong essence, lemon essence, jasmine essence and sweet orange essence.
In a second aspect, the application provides a preparation method of skin care degerming washing-free gel, which adopts the following technical scheme: a skin care sterilizing washing-free gel is prepared by mixing Aloe extract, sodium chloride and deionized water, adding hypochlorous acid and humectant, mixing, adding plant essential oil and essence, mixing, adding trisodium phosphate and sodium metasilicate, stirring, and adjusting pH to 5-7.
By adopting the technical scheme, the preparation method is simple and the conditions are easy to control.
In summary, the application has the following beneficial effects:
1. the application adopts aloe extract, humectant, hypochlorous acid and other components to prepare the no-clean gel, which can effectively kill hand bacteria, has small irritation to skin, achieves the use effects of skin care, moisturizing and quick drying, is an ideal disinfection product for daily use, and is especially suitable for no-clean disinfection, sterilization and bacteriostasis of hands, so as to prevent contact and infectious diseases.
2. In the application, sodium hyaluronate, propylene glycol, jojoba seed oil and a sphenoides extract are preferably used as moisturizers, so that the washing-free gel is moist and elastic to the hand skin after being used.
3. The application preferably uses high molecular weight sodium hyaluronate, sea fennel extract and isopropyl myristate, and under the penetration promoting effect of isopropyl myristate, the application achieves the functions of deep nourishing and surface moisturizing, so that the washing-free condensation achieves the functions of moisturizing while sterilizing.
4. In the application, the corn sprout extract and the hydrolytic cellulose are preferably added into the no-clean condensation as stabilizers, so that the stability of the no-clean condensation at high and low temperatures can be improved, and the no-clean condensation is not easy to be turbid and differentiated.
Detailed Description
Preparation examples 1 to 7 of moisturizer
Preparation example 1: uniformly mixing 1kg of sodium hyaluronate, 0.7kg of propylene glycol, 0.3kg of a butterfly bean flower extract, 0.3kg of PEG-40 hydrogenated castor oil and 0.1kg of caprylic/capric triglyceride, wherein the sodium hyaluronate comprises isopropyl myristate, a sea fennel extract and high molecular weight sodium hyaluronate with the mass ratio of 0.3:1:1 as a phase A;
mixing 0.5kg jojoba seed oil, 1kg glycerol and 2kg distilled water, and performing constant temperature water bath at 50deg.C for 30min to obtain phase B; adding phase B into phase A, stirring for 30min, and homogenizing under 30MPa for 5min to obtain humectant.
Preparation example 2: uniformly mixing 1kg of sodium hyaluronate, 0.2kg of propylene glycol, 0.1kg of a butterfly bean flower extract, 0.1kg of PEG-40 hydrogenated castor oil and 0.05kg of caprylic/capric triglyceride, wherein the sodium hyaluronate comprises isopropyl myristate, a sea fennel extract and high molecular weight sodium hyaluronate with the mass ratio of 0.1:0.5:1 as a phase A;
mixing 0.2kg jojoba seed oil, 0.5kg glycerol and 2kg distilled water, and performing constant temperature water bath at 45deg.C for 20min to obtain phase B; adding phase B into phase A, stirring for 20min, and homogenizing under 35MPa for 3min to obtain humectant.
Preparation example 3: the difference from preparation example 1 is that allantoin was used instead of the extract of the pterostium.
Preparation example 4: the difference from preparation 1 is that tea tree oil was used instead of jojoba seed oil.
Preparation example 5: the difference from preparation example 1 is that isopropyl myristate and sea fennel extract were not added to sodium hyaluronate.
Preparation example 6: the difference from preparation example 1 is that sodium hyaluronate includes isopropyl myristate and high molecular weight sodium hyaluronate having a molecular weight of 150W in a mass ratio of 0.3:1.
Preparation example 7: the difference from preparation example 1 is that sodium hyaluronate comprises a sea fennel extract and a high molecular weight sodium hyaluronate having a molecular weight of 150W in a mass ratio of 1:1.
Examples
Example 1: the skin care degerming washing-free gel has the raw material dosage shown in table 1, wherein the plant essential oil is rose essential oil, the essence is ancient Long Xiangjing, the humectant comprises sodium hyaluronate and propylene glycol in a mass ratio of 1:0.7, and the molecular weight of the sodium hyaluronate is 80W.
The preparation method of the skin care degerming washing-free gel comprises the following steps:
mixing aloe extract, sodium chloride and deionized water, adding hypochlorous acid and humectant, mixing, adding plant essential oil and essence, mixing, adding trisodium phosphate and sodium metasilicate, stirring, and regulating pH to 7 to obtain skin care sterilizing and washing-free gel.
TABLE 1 raw materials amounts of skin care degerming leave-on gel of examples 1-3 and example 11
| Raw materials/% | Example 1 | Example 2 | Example 3 | Example 11 |
| Humectant type | 2 | 1.5 | 1 | 2 |
| Aloe extract | 2 | 1 | 0.5 | 2 |
| Plant essential oil | 0.05 | 0.03 | 0.01 | 0.05 |
| Essence | 0.07 | 0.05 | 0.04 | 0.07 |
| Hypochlorous acid | 0.08 | 0.04 | 0.003 | 0.08 |
| Trisodium phosphate | 1.5 | 1 | 0.5 | 1.5 |
| Sodium metasilicate | 6 | 5 | 4 | 6 |
| Sodium chloride | 1 | 0.8 | 0.5 | 0.1 |
| Stabilizing agent | 0 | 0 | 0 | 1.5 |
| Deionized water | Allowance of | Allowance of | Allowance of | Allowance of |
Example 2: the skin care degerming no-wash gel is different from example 1 in that the raw material dosage is shown in table 1, the humectant comprises sodium hyaluronate and propylene glycol in a mass ratio of 1:0.2, and the molecular weight of the sodium hyaluronate is 150W.
Example 3: a skin care degerming no-wash gel is different from example 1 in that the raw material amounts are shown in Table 1.
Example 4: a skin care degerming no-wash gel is different from example 1 in that a humectant is prepared from preparation 1.
Example 5: a skin care degerming no-wash gel is different from example 1 in that a humectant is prepared from preparation 2.
Example 6: a skin care degerming no-wash gel is different from example 1 in that the humectant is made from preparation 3.
Example 7: a skin care degerming leave-on gel is different from example 1 in that a humectant is prepared from preparation 4.
Example 8: a skin care degerming leave-on gel is different from example 1 in that a humectant is prepared from preparation 5.
Example 9: a skin care degerming no-wash gel is different from example 1 in that a humectant is prepared from preparation 6.
Example 10: a skin care degerming no-wash gel is different from example 1 in that a humectant is prepared from preparation 7.
Example 11: a skin care degerming washing-free gel is different from example 4 in that the raw materials are shown in Table 1, and the stabilizer is hydrogenated lecithin;
the preparation method of the skin care degerming washing-free gel comprises the following steps:
mixing aloe extract and deionized water, adding hypochlorous acid, humectant and stabilizer, mixing, adding plant essential oil and essence, mixing, adding trisodium phosphate and sodium metasilicate, stirring, and regulating pH to 7 to obtain skin care sterilizing and washing-free gel.
Example 12: the skin care degerming no-wash gel is different from example 11 in that the stabilizer comprises corn sprout extract and hydrolyzed corn cellulose in a mass ratio of 1:1, and the preparation method of the hydrolyzed corn cellulose comprises the following steps: mixing corn cellulose and 1mol/l sulfuric acid solution according to a feed-liquid ratio of 1:10, hydrolyzing for 1.5h at 50 ℃, adding distilled water with 10 times of the volume of the sulfuric acid solution, uniformly mixing, centrifuging, washing to be neutral, freeze-drying, and grinding to obtain powder; the powder was prepared into a suspension with a mass fraction of 1% with distilled water, and after ultrasonic dispersion, homogenized for 5min at 40 MPa.
Example 13: the skin care degerming no-wash gel is different from example 11 in that the stabilizer comprises corn sprout extract and hydrolyzed corn cellulose in a mass ratio of 1:0.5, and the preparation method of the hydrolyzed corn cellulose comprises the following steps: mixing corn cellulose and 1mol/l sulfuric acid solution according to a feed-liquid ratio of 1:11, hydrolyzing for 2 hours at 45 ℃, adding distilled water with 10 times of the volume of the sulfuric acid solution, uniformly mixing, centrifuging, washing to be neutral, freeze-drying, grinding, and preparing into powder; the powder was prepared into a suspension with a mass fraction of 0.8% with distilled water, and after ultrasonic dispersion, homogenized at 36MPa for 6min.
Example 14: a skin care degerming no-wash gel differs from example 12 in that the stabilizer is corn sprout extract.
Example 15: a skin care degerming no-wash gel differs from example 12 in that the stabilizer is hydrolyzed corn cellulose.
Comparative example
Comparative example 1: a skin care degerming no-wash gel is different from example 1 in that no humectant is added.
Comparative example 2: a skin care degerming leave-on gel is different from example 1 in that aloe extract is not added.
Comparative example 3: the hand-protecting type washing-free disinfection gel comprises the following raw materials in parts by mass: 0.1% of bactericide, 2.1% of cosolvent, 0.10% of thickener, 0.01% of emollient, 1.8% of essence, 0.02% of PH value regulator, 39% of ethanol and the balance of water.
The method for preparing the hand-protecting type no-clean disinfection gel can be carried out according to the following steps:
(1) Weighing the components according to the proportion, adding water accounting for 30% of the total weight of the hand disinfectant into a stainless steel reaction pot, slowly adding the thickener for 3 times while stirring, mechanically stirring at a speed of 90r/min for 120 minutes, dispersing to a uniform turbid dispersion, standing overnight, and fully swelling to obtain solution A;
(2) Adding ethanol accounting for 30% of the hand disinfectant into another stainless steel reaction pot, adding a bactericide and a cosolvent, mixing and dissolving, mechanically stirring at a speed of 60r/min for 8 minutes until the solution is clear, preparing solution B, and sealing and preserving for later use;
(3) Pouring the solution B into the solution A, adding the rest ethanol, stirring at a speed of 60r/min, and sequentially adding the emollient, the essence and the residual water until the pH value is 6.0.
Comparative example 4: sterilizing alcohol with concentration of 75%.
Performance test
A no-wash gel was prepared according to the methods in examples and comparative examples, and the performance of the no-wash gel was measured with reference to the following methods, and the measurement results are recorded in table 2.
1. Antibacterial rate: according to GB15979-2002 "hygienic Standard for Single use", the 6 th Generation of Escherichia coli (ATCC 8099) is treated with a 1:1 dilution for 2 minutes and the 6 th generation of Staphylococcus aureus (ATCC 6538) is treated with a 1:1 dilution for 2 minutes.
2. Quick-drying test: 1ml of the washing-free gel is uniformly smeared on the palm of a user, timing is started from the uniform smearing until the gel smeared on the hands is completely dried, 10 people in each group take the average value of the test results, and the test temperature is room temperature.
3. Moisturizing effect: each group selects 10 female testers, the back of the hand is used as a test part during the test, and a fixed area with the size of 2 square centimeters is drawn on the back of the hand as a test area. The skin moisture content of the skin was measured on the skin of the back of each group of 10 female testers using a skin moisture meter in an indoor environment at 20 ℃ and 50% relative humidity, the results were represented by set humidity measurement values (Moisture Measurement Value, MMV), and the final MMV values were represented by average results to evaluate the moisturizing performance of the product. Wherein: MMV 0-skin MMV value before wash-free gel washing, MMV 1-skin MMV value after wash-free gel washing for 2 hours; moisture retention = MMV1/MMV0 x 100%.
4. Stability: (1) high temperature stability: standing the sample at 70 ℃ for 5 hours, observing whether layering or sedimentation occurs, and if no obvious layering or sedimentation occurs when the sample is kept at 70 ℃ for 5 hours, indicating that the high-temperature stability is better; otherwise, it indicates poor high temperature stability.
(2) The low-temperature stability test method comprises the following steps: standing the sample at-20 ℃ for 2 hours, observing whether layering or sedimentation occurs, and if no obvious layering or sedimentation occurs when the sample is kept at-20 ℃ for 2 hours, indicating that the low-temperature stability is better; otherwise, it indicates poor low temperature stability.
TABLE 2 Performance test results of skin care degerming leave-in gel
In combination with the contents of example 2 and examples 1 to 3, it can be seen that the leave-on gel prepared in examples 1 to 3 has a good antibacterial effect, and has a high volatilization speed, does not generate a sticky feel, has a good moisturizing effect, is not easy to cause skin dryness, and still has the problem of poor stability.
The moisturizing agents prepared in preparation examples 1 and 2 were used in examples 4 and 5, respectively, and the moisturizing rates of the leave-on gels prepared in examples 4 and 5 were increased and the stability improvement effect was not obvious, compared with example 1.
Example 6 using the moisturizer prepared in preparation example 3, the use of allantoin instead of the extract of the pterostium indicum flower compared with preparation example 1, shows in table 2 that the antibacterial rate is reduced and the moisturizing rate is reduced compared with example 4, but the effect is still better than that of example 1.
The moisturizing agent prepared in preparation example 4 was used in example 7, wherein tea tree oil was used instead of jojoba seed oil, and table 2 shows that the antibacterial rate of the leave-in gel prepared in example 7 was increased compared to example 4, but the moisturizing rate was inferior to that of example 4.
The moisturizing agent prepared in preparation example 5 was used in example 8, wherein sodium hyaluronate only contains high molecular weight sodium hyaluronate, the moisturizing agents prepared in preparation example 6 and preparation example 7 were used in example 9 and example 10, respectively, no sea fennel extract and isopropyl myristate were added in preparation example 6 and preparation example 7, respectively, no-wash-free gels were prepared in example 9 and example 10, the moisturizing effect was better than in example 8, but still weaker than in example 4, and the volatilization time of no-wash gels in example 8 and example 10 was increased.
Example 11 also shows, in Table 2, that the stability of the leave-on gel prepared in example 11 at high and low temperatures is improved by the addition of a stabilizer as compared to example 4.
The examples 12 and 13 are comparative to example 4 in that the stabilizers are corn sprout extract and hydrolyzed corn cellulose, and the examples 12 and 13 are comparative in that the wash-free gels have good stability at high and low temperatures and better stability than example 11.
In examples 13 and 14, the high temperature stability and low temperature stability of the no-wash gel were significantly reduced as compared with example 12, without the addition of the hydrolyzed corn cellulose and corn sprout extract, respectively.
The moisturizing agent and aloe extract are not added in comparative examples 1 and 2, respectively, and the moisturizing rate of the leave-on condensation prepared in comparative example 1 is remarkably reduced, and the leave-on condensation prepared in comparative example 2 is reduced in moisturizing ability and also reduced in antibacterial effect, as compared with example 1.
Comparative example 3 is a leave-in product in the prior art, which has poor antibacterial rate and insufficient moisture retention, and comparative example 4 is high-concentration ethanol, which has good antibacterial effect and short volatilization time, but has poor moisture retention and is liable to cause skin dryness.
The washing-free condensation prepared in example 1, example 4 and example 12 is tested according to the second part of the ministry of health of the people's republic of China (2002 edition) of the second part of the technical Specification of the toxicology experiment of disinfecting products, and the results show that: the rabbits are subjected to multiple complete skin stimulation tests, the total integral average value is 0.09, the skin stimulation index is 0-0.5, and the stimulation intensity belongs to no stimulation.
The present embodiment is only for explanation of the present application and is not to be construed as limiting the present application, and modifications to the present embodiment, which may not creatively contribute to the present application as required by those skilled in the art after reading the present specification, are all protected by patent laws within the scope of claims of the present application.
Claims (10)
1. The skin-care degerming washing-free gel is characterized by comprising the following raw materials in percentage by weight: 1-2% of humectant, 0.5-2% of aloe extract, 0.01-0.05% of plant essential oil, 0.04-0.07% of essence, 0.003-0.08% of hypochlorous acid, 0.5-1.5% of trisodium phosphate, 4-6% of sodium metasilicate, 0.1-1% of sodium chloride and the balance of deionized water.
2. The skin care, sterilization and leave-in gel according to claim 1, wherein: the humectant is at least one selected from sodium hyaluronate, propylene glycol, jojoba seed oil, flos Camelliae Japonicae extract, allantoin, tea tree oil and herba Violae Japonicae extract.
3. The skin care and sterilization leave-on gel according to claim 2, wherein the humectant comprises sodium hyaluronate and propylene glycol in a mass ratio of 1 (0.2-0.7).
4. The skin care sterilizing no-clean gel according to claim 2, wherein the humectant comprises sodium hyaluronate, propylene glycol, jojoba seed oil and a sphenoides extract in a mass ratio of 1 (0.2-0.7): (0.2-0.5): (0.1-0.3).
5. The skin care and sterilization leave-in gel according to claim 4, wherein the method for preparing the moisturizer comprises the steps of:
uniformly mixing sodium hyaluronate, propylene glycol, a butterfly bean flower extract, PEG-40 hydrogenated castor oil and caprylic/capric triglyceride to obtain phase A;
mixing jojoba seed oil, glycerol and distilled water, and performing constant temperature water bath at 45-50deg.C for 20-30min to obtain phase B;
adding phase B into phase A, stirring for 20-30min, and homogenizing under 30-35MPa to obtain humectant.
6. The skin care antibacterial leave-on gel according to claim 2, wherein the sodium hyaluronate comprises isopropyl myristate, sea fennel extract and high molecular weight sodium hyaluronate having a molecular weight of 80-150W in a mass ratio of (0.1-0.3): (0.5-1): 1.
7. The skin care sterilizing no-clean gel according to claim 1, further comprising 0.05-0.15% of stabilizer by mass.
8. The skin care and sterilization leave-on gel according to claim 7 wherein the stabilizer comprises corn sprout extract and hydrolyzed corn cellulose in a mass ratio of 0.5-1:1.
9. The skin care and sterilization leave-in gel according to claim 1, wherein the plant essential oil is at least one selected from the group consisting of rose essential oil, chrysanthemum essential oil, tea tree essential oil, peppermint essential oil;
the essence is at least one selected from Gulong essence, lemon essence, jasmine essence and sweet orange essence.
10. The method for preparing the skin care degerming leave-on gel according to any one of claims 1 to 9, which is characterized by comprising the following steps:
mixing aloe extract, sodium chloride and deionized water, adding hypochlorous acid and humectant, mixing, adding plant essential oil and essence, mixing, adding trisodium phosphate and sodium metasilicate, stirring, and regulating pH to 5-7 to obtain skin care sterilizing and washing-free gel.
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| CN202311028372.0A CN116869899A (en) | 2023-08-16 | 2023-08-16 | Skin-care degerming washing-free gel and preparation method thereof |
| CN202311342382.1A CN117503667A (en) | 2023-08-16 | 2023-10-17 | Skin-care degerming washing-free gel and preparation method thereof |
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| CN202311028372.0A CN116869899A (en) | 2023-08-16 | 2023-08-16 | Skin-care degerming washing-free gel and preparation method thereof |
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| CN202311028372.0A Withdrawn CN116869899A (en) | 2023-08-16 | 2023-08-16 | Skin-care degerming washing-free gel and preparation method thereof |
| CN202311342382.1A Pending CN117503667A (en) | 2023-08-16 | 2023-10-17 | Skin-care degerming washing-free gel and preparation method thereof |
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