CN1167462C - 一种含环孢素的药物组合物 - Google Patents

一种含环孢素的药物组合物 Download PDF

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Publication number
CN1167462C
CN1167462C CNB991028481A CN99102848A CN1167462C CN 1167462 C CN1167462 C CN 1167462C CN B991028481 A CNB991028481 A CN B991028481A CN 99102848 A CN99102848 A CN 99102848A CN 1167462 C CN1167462 C CN 1167462C
Authority
CN
China
Prior art keywords
pharmaceutical composition
acid
ciclosporin
cyclosporin
oily components
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB991028481A
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English (en)
Chinese (zh)
Other versions
CN1265920A (zh
Inventor
张泳华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hangzhou Huadong Medicine Group Biological Engineering Research Institute Co., Ltd.
Hangzhou Zhongmei Huadong Pharmaceutical Co Ltd
Original Assignee
Hangzhou Huadong Medicine Group Biological Engineering Research Institute Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CNB991028481A priority Critical patent/CN1167462C/zh
Application filed by Hangzhou Huadong Medicine Group Biological Engineering Research Institute Co Ltd filed Critical Hangzhou Huadong Medicine Group Biological Engineering Research Institute Co Ltd
Priority to KR1020017011483A priority patent/KR20010112315A/ko
Priority to DE10084344T priority patent/DE10084344T1/de
Priority to BR0010454-0A priority patent/BR0010454A/pt
Priority to PCT/CN2000/000041 priority patent/WO2000053212A1/zh
Priority to AU27927/00A priority patent/AU2792700A/en
Priority to GB0121845A priority patent/GB2363572B/en
Publication of CN1265920A publication Critical patent/CN1265920A/zh
Application granted granted Critical
Publication of CN1167462C publication Critical patent/CN1167462C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNB991028481A 1999-03-09 1999-03-09 一种含环孢素的药物组合物 Expired - Lifetime CN1167462C (zh)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CNB991028481A CN1167462C (zh) 1999-03-09 1999-03-09 一种含环孢素的药物组合物
DE10084344T DE10084344T1 (de) 1999-03-09 2000-03-02 Cyclosporin enthaltende pharmazeutische Zusammensetzung
BR0010454-0A BR0010454A (pt) 1999-03-09 2000-03-02 Composição farmacêutica contendo ciclosporina
PCT/CN2000/000041 WO2000053212A1 (fr) 1999-03-09 2000-03-02 Composition pharmaceutique contenant une cyclosporine
KR1020017011483A KR20010112315A (ko) 1999-03-09 2000-03-02 사이클로스포린을 함유하는 약학 조성물
AU27927/00A AU2792700A (en) 1999-03-09 2000-03-02 Pharmaceutical composition containing cyclosporin
GB0121845A GB2363572B (en) 1999-03-09 2000-03-02 Pharmaceutical composition containing cyclosporin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB991028481A CN1167462C (zh) 1999-03-09 1999-03-09 一种含环孢素的药物组合物

Publications (2)

Publication Number Publication Date
CN1265920A CN1265920A (zh) 2000-09-13
CN1167462C true CN1167462C (zh) 2004-09-22

Family

ID=5271009

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB991028481A Expired - Lifetime CN1167462C (zh) 1999-03-09 1999-03-09 一种含环孢素的药物组合物

Country Status (7)

Country Link
KR (1) KR20010112315A (pt)
CN (1) CN1167462C (pt)
AU (1) AU2792700A (pt)
BR (1) BR0010454A (pt)
DE (1) DE10084344T1 (pt)
GB (1) GB2363572B (pt)
WO (1) WO2000053212A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60221287T4 (de) * 2001-11-08 2009-06-25 Atrium Medical Corp. Intraluminale vorrichtung mit einer ein therapeutisches-mittel enthaltenden beschichtung
PT1660047E (pt) 2003-08-13 2014-02-27 Biocon Ltd Formulação de dosagem sólida de sais de ácidos gordos em micropartículas para agentes terapêuticos
US9801913B2 (en) 2004-09-28 2017-10-31 Atrium Medical Corporation Barrier layer
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
KR100678829B1 (ko) * 2004-12-06 2007-02-05 한미약품 주식회사 타크로리무스의 경구용 마이크로에멀젼 조성물
CN100478025C (zh) * 2005-03-25 2009-04-15 中国科学院上海药物研究所 一种环孢菌素a眼用微乳制剂及其制备方法
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
CN101502641B (zh) * 2009-02-23 2012-05-02 姚定全 一种注射给药的环孢素药物组合物
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
EP2593141B1 (en) 2010-07-16 2018-07-04 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
KR101363776B1 (ko) * 2012-12-21 2014-02-17 이상필 사이클로스포린을 포함하는 투명 점안액 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL102236A0 (en) * 1991-06-27 1993-01-14 Ltt Inst Co Ltd Topical preparations containing cyclosporin
GB9113872D0 (en) * 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
KR940002128Y1 (ko) * 1992-04-21 1994-04-06 배순훈 비데오 테이프 레코더의 테이프 로딩장치
US5603951A (en) * 1994-11-09 1997-02-18 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
KR0167613B1 (ko) * 1994-12-28 1999-01-15 한스 루돌프 하우스, 니콜 케르커 사이클로스포린-함유 연질캅셀제 조성물
DE19549852B4 (de) * 1995-11-29 2009-06-04 Novartis Ag Cyclosporin enthaltende Präparate

Also Published As

Publication number Publication date
GB2363572B (en) 2004-02-18
DE10084344T1 (de) 2002-07-11
CN1265920A (zh) 2000-09-13
BR0010454A (pt) 2002-01-08
WO2000053212A1 (fr) 2000-09-14
GB2363572A (en) 2002-01-02
KR20010112315A (ko) 2001-12-20
GB0121845D0 (en) 2001-10-31
AU2792700A (en) 2000-09-28

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract

Assignee: Zhongmei Huadong Pharmaceutical Co., Ltd., Hangzhou

Assignor: Hangzhou Huadong Medicine Group Biological Engineering Research Institute Co., Ltd.

Contract fulfillment period: 2008.7.5 to 2018.7.5

Contract record no.: 2008330000426

Denomination of invention: Medicinal composition containing cyclosporin

Granted publication date: 20040922

License type: Exclusive license

Record date: 2008.9.10

LIC Patent licence contract for exploitation submitted for record

Free format text: EXCLUSIVE LICENCE; TIME LIMIT OF IMPLEMENTING CONTACT: 2008.7.5 TO 2018.7.5

Name of requester: ZHONGMEI HUADONG PHARMACEUTICAL CO., LTD. HANGZHO

Effective date: 20080910

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20160418

Address after: 310012 West Lake international science and technology building, No. 391 Wen two road, Hangzhou, Zhejiang, C910, Xihu District

Patentee after: Hangzhou Huadong Medicine Group Biological Engineering Research Institute Co., Ltd.

Patentee after: Zhongmei Huadong Pharmaceutical Co., Ltd., Hangzhou

Address before: Hangzhou City, Zhejiang province 310011 Moganshan Road No. 866

Patentee before: Hangzhou Huadong Medicine Group Biological Engineering Research Institute Co., Ltd.

CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20040922