CN116725919A - Preparation method and application of gentian extract - Google Patents
Preparation method and application of gentian extract Download PDFInfo
- Publication number
- CN116725919A CN116725919A CN202310763971.0A CN202310763971A CN116725919A CN 116725919 A CN116725919 A CN 116725919A CN 202310763971 A CN202310763971 A CN 202310763971A CN 116725919 A CN116725919 A CN 116725919A
- Authority
- CN
- China
- Prior art keywords
- parts
- gentian extract
- time
- preparation
- liquid medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000284 extract Substances 0.000 title claims abstract description 61
- 241001071795 Gentiana Species 0.000 title claims abstract description 59
- 238000002360 preparation method Methods 0.000 title claims abstract description 34
- 239000003814 drug Substances 0.000 claims abstract description 37
- 239000007788 liquid Substances 0.000 claims abstract description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- 239000000203 mixture Substances 0.000 claims abstract description 22
- 239000000341 volatile oil Substances 0.000 claims abstract description 22
- 244000178231 Rosmarinus officinalis Species 0.000 claims abstract description 20
- 239000002904 solvent Substances 0.000 claims abstract description 20
- 239000000654 additive Substances 0.000 claims abstract description 18
- 230000000996 additive effect Effects 0.000 claims abstract description 18
- 235000007215 black sesame Nutrition 0.000 claims abstract description 17
- 125000003118 aryl group Chemical group 0.000 claims abstract description 16
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 14
- 235000017784 Mespilus germanica Nutrition 0.000 claims abstract description 13
- 244000182216 Mimusops elengi Species 0.000 claims abstract description 13
- 235000000560 Mimusops elengi Nutrition 0.000 claims abstract description 13
- 235000007837 Vangueria infausta Nutrition 0.000 claims abstract description 13
- 238000000605 extraction Methods 0.000 claims abstract description 11
- 238000000034 method Methods 0.000 claims abstract description 11
- 244000061520 Angelica archangelica Species 0.000 claims abstract description 10
- 235000001287 Guettarda speciosa Nutrition 0.000 claims abstract description 10
- 239000003205 fragrance Substances 0.000 claims abstract description 4
- 238000010438 heat treatment Methods 0.000 claims description 34
- 238000001816 cooling Methods 0.000 claims description 29
- 238000005303 weighing Methods 0.000 claims description 24
- 238000003756 stirring Methods 0.000 claims description 21
- 238000001914 filtration Methods 0.000 claims description 13
- 230000000694 effects Effects 0.000 claims description 12
- 239000000047 product Substances 0.000 claims description 7
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 6
- 150000002148 esters Chemical class 0.000 claims description 6
- 238000005360 mashing Methods 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 6
- 238000004806 packaging method and process Methods 0.000 claims description 6
- -1 polyoxyethylene Polymers 0.000 claims description 6
- 235000005979 Citrus limon Nutrition 0.000 claims description 5
- 244000131522 Citrus pyriformis Species 0.000 claims description 5
- 241000220317 Rosa Species 0.000 claims description 5
- 240000000513 Santalum album Species 0.000 claims description 5
- 235000008632 Santalum album Nutrition 0.000 claims description 5
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 5
- 239000004202 carbamide Substances 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 239000003086 colorant Substances 0.000 claims description 5
- 239000003906 humectant Substances 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 229920000136 polysorbate Polymers 0.000 claims description 5
- 229950008882 polysorbate Drugs 0.000 claims description 5
- 239000013589 supplement Substances 0.000 claims description 5
- 244000241838 Lycium barbarum Species 0.000 claims description 4
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 4
- 235000015468 Lycium chinense Nutrition 0.000 claims description 4
- 235000013399 edible fruits Nutrition 0.000 claims description 4
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 3
- 235000006679 Mentha X verticillata Nutrition 0.000 claims description 3
- 235000002899 Mentha suaveolens Nutrition 0.000 claims description 3
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims description 3
- 244000131316 Panax pseudoginseng Species 0.000 claims description 3
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 3
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 3
- 230000003110 anti-inflammatory effect Effects 0.000 claims description 3
- SRSXLGNVWSONIS-UHFFFAOYSA-M benzenesulfonate Chemical compound [O-]S(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-M 0.000 claims description 3
- 229940077388 benzenesulfonate Drugs 0.000 claims description 3
- 239000012153 distilled water Substances 0.000 claims description 3
- 235000008434 ginseng Nutrition 0.000 claims description 3
- 239000003755 preservative agent Substances 0.000 claims description 3
- 230000002335 preservative effect Effects 0.000 claims description 3
- 230000000844 anti-bacterial effect Effects 0.000 claims description 2
- 239000002537 cosmetic Substances 0.000 claims description 2
- 238000012958 reprocessing Methods 0.000 claims description 2
- 238000003860 storage Methods 0.000 claims description 2
- 239000002304 perfume Substances 0.000 claims 3
- 241000213006 Angelica dahurica Species 0.000 claims 1
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims 1
- 230000001815 facial effect Effects 0.000 abstract description 7
- 239000002994 raw material Substances 0.000 abstract description 7
- 230000003266 anti-allergic effect Effects 0.000 abstract description 5
- 230000008569 process Effects 0.000 abstract description 4
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 description 15
- 235000013599 spices Nutrition 0.000 description 12
- 241000382455 Angelica sinensis Species 0.000 description 6
- 208000001840 Dandruff Diseases 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 238000003908 quality control method Methods 0.000 description 3
- 201000004384 Alopecia Diseases 0.000 description 2
- 241000132012 Atractylodes Species 0.000 description 2
- 244000197580 Poria cocos Species 0.000 description 2
- 235000008599 Poria cocos Nutrition 0.000 description 2
- 231100000360 alopecia Toxicity 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 239000004519 grease Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000501743 Gentiana macrophylla Species 0.000 description 1
- 241000486199 Gentiana rigescens Species 0.000 description 1
- 241001275898 Mylopharyngodon piceus Species 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 230000003779 hair growth Effects 0.000 description 1
- 230000003752 improving hair Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000004800 psychological effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000001603 reducing effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a preparation method and application of gentian extract, relating to the technical field of hair care liquid medicine preparation, and comprising the following compositions: the invention has the beneficial effects that water, gentian extract, butanediol, black sesame, medlar, angelica, rosemary essential oil, medicinal liquor, aromatic, additive and solubilizer are included: according to the preparation method, the gentian extract is prepared according to the processes of raw material pretreatment preparation, raw material preliminary extraction treatment, raw material final extraction treatment and finished product preparation treatment, the anti-allergic effect is enhanced through industrial operation, and the auxiliary component extract is added, so that the gentian extract has different types of fragrances when in use, meets the use requirements of different crowds, is suitable for resisting skin and improving facial skin, and improves the flexibility when in use.
Description
Technical Field
The invention relates to the technical field of hair care liquid medicine preparation, in particular to a preparation method and application of gentian extract.
Background
Gentian is a perennial herb of gentiaceae, mainly produced in northeast and Yunnan, and is considered bitter and cold in nature by traditional Chinese medicine; enter liver and gallbladder meridians; has effects of clearing heat, eliminating dampness, purging liver fire, and invigorating stomach. Wherein the gentiana rigescens is named as gentian, bitter grass, black carp gall, gentiana macrophylla, and the like, which are perennial herbaceous plants of gentiaceae, mainly produced in Yunnan, is one of traditional Chinese medicine gentian varieties and is recorded as a folk important medicine. Because of its effects of clearing damp-heat, benefiting liver and gall, invigorating stomach, sterilizing, anti-inflammatory, reducing weight, etc., it is used as a bitter stomach-invigorating medicine in modern medicine.
At present, the gentian extract has large solvent consumption during extraction, long process consumption, large density difference of the extracts prepared each time, poor overall quality control, and single auxiliary facial beautifying operation, incapability of improving skin grease problem, and poor overall flexibility, and cannot meet the requirements of normal use, so the invention needs to design a gentian extract preparation method and application to solve the problems.
Disclosure of Invention
The invention aims to provide a preparation method and application of gentian extract, which are used for solving the problems that the prior gentian extract has large solvent consumption during extraction, long process consumption, large density difference of each prepared extract, poor overall quality control, and poor overall flexibility, and can not meet the requirements of normal use because only single facial auxiliary beautifying operation can be carried out, and the problem of skin grease can not be improved.
In order to achieve the above purpose, the invention provides a preparation method of gentian extract, which comprises the following compositions: water, gentian extract, butylene glycol, black sesame, wolfberry fruit, chinese angelica, rosemary essential oil, medicinal liquor, aromatic, additive and solubilizer;
the preparation method comprises the following steps:
s1, weighing gentian extract, butanediol, black sesame, medlar and angelica according to the required weight parts, mashing and mixing, adding water, heating and stirring for the first time, extracting residues, and performing first filtering treatment to obtain liquid medicine for the first treatment;
s2, weighing the essential oil and the solubilizer of the rosemary according to the preparation proportion, respectively pouring the essential oil and the solubilizer into the liquid medicine treated for the first time, carrying out first standing and cooling, adding the medicinal liquor, carrying out second heating and stirring, extracting residues, carrying out second filtering treatment to obtain the liquid medicine treated for the second time, and carrying out second standing and cooling;
s3, weighing the required weight parts of the aromatic and the additive according to the manufacturing proportion, stirring for the third time to obtain a finished liquid medicine product, standing and cooling for the third time, weighing the liquid medicine with the required weight, and finally packaging.
Preferably, the weight parts of the compositions are 100 to 1000 parts of water, 30 to 100 parts of gentian extract, 10 to 40 parts of butanediol, 5 to 10 parts of black sesame, 5 to 15 parts of medlar, 3 to 15 parts of angelica, 2 to 10 parts of rosemary essential oil, 10 to 50 parts of medicinal liquor, 1 to 3 parts of aromatic, 1 to 6 parts of additive and 1 to 10 parts of solubilizer respectively.
Preferably, the aromatic is one or more of a sandalwood rose type spice, a lemon mixture type spice and a mint type spice, the additive is one or more of an antidandruff agent, a humectant, a preservative, a colorant and a supplement, and the solubilizer is one or more of polysorbate, polyoxyethylene ester, urea and short-chain benzene sulfonate.
Preferably, the water is one or more of natural spring water, distilled water and snow mountain water, and the medicinal liquor comprises a mixture of ginseng, poria cocos and bighead atractylodes rhizome.
Preferably, the first heating time in the step S1 is 30-60min and the first heating temperature is 70-80 ℃, the second heating time in the step S2 is 40-80min and the second heating temperature is 80-100 ℃, and the third stirring time in the step S3 is 10-20min.
Preferably, the first standing cooling time in the step S2 is 1-2h, the second standing cooling time in the step S2 is 1.5-2h, and the third standing cooling time in the step S3 is 2-3h.
Preferably, the extraction residues in the step S1 and the step S2 are reprocessed, and the residual liquid is extracted and stored to obtain the supplement.
Preferably, the ratio of fragrance to additive is 1:2.
Preferably, the gentian extract is used for improving hair and face.
Compared with the prior art, the invention has the beneficial effects that: when the Chinese medicinal composition is used, the Chinese gentian extract is prepared by adding water, chinese gentian extract, butanediol, black sesame, medlar, angelica, rosemary essential oil, medicinal liquor, aromatic, additive and solubilizer into the medicinal liquid of the composition according to the processes of raw material pretreatment preparation, raw material preliminary extraction treatment, raw material final extraction treatment and finished product preparation treatment, the treatment effect of each raw material is improved by heating, stirring, filtering and airing twice, the density uniformity of the extract prepared each time is effectively ensured by industrial operation, the overall quality control is improved, the aromatic effect during use is improved by adding the aromatic, the irritation effect can be reduced, the dysphoria psychological effect of alopecia personnel can be relieved, the hair growth is facilitated, the alopecia prevention effect is achieved, the moisturizing, corrosion preventing and dandruff removing effects of the medicinal liquid are improved by adding the additive, the Chinese medicinal composition is suitable for personnel with different symptoms, the overall use flexibility is improved, and the Chinese medicinal composition is suitable for hairdressing and improving the skin.
Detailed Description
The invention provides a technical scheme that: a preparation method of radix Gentianae extract comprises the following compositions: water, gentian extract, butylene glycol, black sesame, wolfberry fruit, chinese angelica, rosemary essential oil, medicinal liquor, aromatic, additive and solubilizer;
the preparation method comprises the following steps:
s1, weighing gentian extract, butanediol, black sesame, medlar and angelica which are required by weight parts according to a preparation proportion, mashing and mixing, adding water, heating and stirring for the first time, wherein the first heating time is 30-60min and the first heating temperature is 70-80 ℃, extracting residues, and performing first filtering treatment to obtain a liquid medicine for the first treatment;
s2, weighing the required parts by weight of rosemary essential oil and solubilizer according to the preparation proportion, respectively pouring the rosemary essential oil and the solubilizer into the liquid medicine subjected to the first treatment, carrying out first standing and cooling, wherein the first standing and cooling time is 1-2 hours, adding medicinal liquor, carrying out second heating and stirring, extracting residues of the rosemary essential oil and the solubilizer at the second heating temperature of 80-100 ℃ for 40-80 minutes, carrying out second filtering treatment to obtain the liquid medicine subjected to the second treatment, and carrying out second standing and cooling for 1.5-2 hours;
s3, weighing the required weight parts of the aromatic and the additive according to the manufacturing proportion, stirring for the third time for 10-20min to obtain a finished liquid medicine product, standing and cooling for the third time for 2-3h, weighing the liquid medicine with the required weight, and finally packaging.
Further, the weight parts of the compositions are 100 to 1000 parts of water, 30 to 100 parts of gentian extract, 10 to 40 parts of butanediol, 5 to 10 parts of black sesame, 5 to 15 parts of medlar, 3 to 15 parts of angelica, 2 to 10 parts of rosemary essential oil, 10 to 50 parts of medicinal liquor, 1 to 3 parts of aromatic, 1 to 6 parts of additive and 1 to 10 parts of solubilizer respectively.
Further, the aromatic is one or more of a sandalwood rose type spice, a lemon mixture type spice and a mint type spice, the additive is one or more of an antidandruff agent, a humectant, a preservative, a colorant and a supplement, the solubilizer is one or more of polysorbate, polyoxyethylene ester, urea and short-chain benzene sulfonate, the water is one or more of natural spring water, distilled water and snow mountain water, and the medicinal liquor comprises ginseng, poria cocos and bighead atractylodes rhizome mixture.
Further, reprocessing the extraction residues in the step S1 and the step S2, and extracting residual liquid in the reprocessed extraction residues for storage to obtain the supplement.
Further, the ratio of the fragrance to the additive is 1:2.
Further, an application of gentian extract in preparing cosmetic varieties with skin antibacterial, anti-inflammatory and repairing effects.
Example 1
A preparation method of gentian extract comprises the following components in parts by weight: the composition comprises, by weight, 100 parts of water, 30 parts of gentian extract, 10 parts of butanediol, 5 parts of black sesame, 5 parts of wolfberry fruit, 3 parts of Chinese angelica, 2 parts of rosemary essential oil, 10 parts of medicinal liquor, 1 part of sandalwood rose type spice, 2 parts of anti-dandruff agent and 1 part of polysorbate.
A preparation method of gentian extract comprises the following steps:
s1, weighing 30 parts of gentian extract, 10 parts of butanediol, 5 parts of black sesame, 5 parts of medlar and 3 parts of angelica sinensis according to the required weight parts, mashing and mixing, adding 100 parts of water, heating and stirring for the first time, wherein the first heating time is 30min and the first heating temperature is 70 ℃, extracting residues, and performing first filtering treatment to obtain a liquid medicine for the first treatment;
s2, weighing 2 parts of rosemary essential oil and 1 part of polysorbate according to the preparation proportion, respectively pouring into the liquid medicine subjected to the first treatment, carrying out first standing and cooling, wherein the first standing and cooling time is 1h, adding 10 parts of medicinal liquor, carrying out second heating and stirring, extracting residues at the second heating temperature of 80 ℃ for 40min, carrying out second filtering treatment to obtain the liquid medicine subjected to the second treatment, and carrying out second standing and cooling for 1.5h;
s3, weighing 1 part of the required weight of the sandalwood rose type spice and 2 parts of the anti-dandruff agent according to the manufacturing proportion, stirring for the third time for 10min to obtain a finished liquid medicine product, standing and cooling for the third time for 2h, weighing the liquid medicine with the required weight, and finally packaging.
Example 2
A preparation method of gentian extract comprises the following components in parts by weight: the weight parts of the compositions are 500 parts of water, 80 parts of gentian extract, 20 parts of butanediol, 8 parts of black sesame, 10 parts of medlar, 10 parts of angelica, 5 parts of rosemary essential oil, 30 parts of medicinal liquor, 2 parts of lemon mixture type spice, 4 parts of humectant and 5 parts of urea.
A preparation method of gentian extract comprises the following steps:
s1, weighing 80 parts of gentian extract, 20 parts of butanediol, 8 parts of black sesame, 10 parts of medlar and 10 parts of angelica sinensis according to the required weight parts, mashing and mixing, adding 500 parts of water, heating and stirring for the first time, wherein the first heating time is 50min and the first heating temperature is 75 ℃, extracting residues, and performing first filtering treatment to obtain a liquid medicine for the first treatment;
s2, weighing 5 parts by weight of rosemary essential oil and 5 parts by weight of urea according to the manufacturing proportion, respectively pouring into the liquid medicine subjected to the first treatment, carrying out first standing and cooling, wherein the first standing and cooling time is 1.5h, adding 30 parts of medicinal liquor, carrying out second heating and stirring, extracting residues at the second heating temperature of 90 ℃ for 50min, carrying out second filtering treatment to obtain the liquid medicine subjected to the second treatment, and carrying out second standing and cooling for 1.5h;
s3, weighing 2 parts of lemon mixture type spice and 4 parts of humectant according to the preparation proportion, stirring for the third time for 15min to obtain a finished liquid medicine product, standing and cooling for the third time for 2.5h, weighing the liquid medicine with the required weight, and finally packaging.
Example 3
A preparation method of gentian extract comprises the following components in parts by weight: the weight parts of the compositions are 1000 parts of water, 100 parts of gentian extract, 40 parts of butanediol, 10 parts of black sesame, 15 parts of medlar, 15 parts of angelica, 10 parts of rosemary essential oil, 50 parts of medicinal liquor, 3 parts of mint-type spice, 6 parts of coloring agent and 10 parts of polyoxyethylene ester.
A preparation method of gentian extract comprises the following steps:
s1, weighing 100 parts of gentian extract, 40 parts of butanediol, 10 parts of black sesame, 15 parts of medlar and 15 parts of angelica sinensis according to the required weight parts, mashing and mixing, adding 1000 parts of water, heating and stirring for the first time, wherein the first heating time is 60min and the first heating temperature is 80 ℃, extracting residues, and performing first filtering treatment to obtain a liquid medicine for the first treatment;
s2, weighing 10 parts of rosemary essential oil and 10 parts of polyoxyethylene ester according to the preparation proportion, respectively pouring the rosemary essential oil and the polyoxyethylene ester into the liquid medicine subjected to the first treatment, carrying out first standing and cooling, wherein the first standing and cooling time is 2 hours, adding 50 parts of medicinal liquor, carrying out second heating and stirring, wherein the second heating time is 80 minutes, the second heating temperature is 100 ℃, extracting residues, carrying out second filtering treatment to obtain the liquid medicine subjected to the second treatment, and carrying out second standing and cooling, wherein the second standing and cooling time is 2 hours;
s3, weighing 3 parts of mint-type spice and 6 parts of colorant according to the preparation proportion, stirring for the third time for 20min to obtain a finished liquid medicine product, standing and cooling for the third time for 3h, weighing the liquid medicine with the required weight, and finally packaging.
Performance testing
Gentian extract effect verification experiments in examples 1 to 2
1. Test group
Test group 1-2: gentian extracts prepared in examples 1 to 2
Control group: gentian extract of the prior art.
2. Test method
And respectively taking 1000ml of samples in test groups 1-2 and a control group, grouping the personnel participating in the test, wherein the first test group carries out facial beauty treatment operation on the gentian extract, the second test group carries out antiallergic test operation on the gentian extract, the first test control group carries out facial beauty treatment operation on the gentian extract, and the second test control group carries out antiallergic test operation on the gentian extract.
3. Test results
The detection results are shown in the following table:
the following table shows the results of the detection of gentian extract and control group in examples 1 to 2.
| Grouping | Facial oil and fat percentage | Antiallergic effect | Duration of test |
| Test group 1 | 15％ | 85％ | For 10 days |
| Test group2 | 14％ | 80％ | For 10 days |
| Control group | 25％ | 60％ | For 10 days |
From the data of the detection results in the above table, the actual effect of the gentian extract in the experimental group on antiallergic and facial improvement is far superior to the improvement effect of the gentian extract in the prior art.
In the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "configured," "connected," "secured," "screwed," and the like are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intermediaries, or in communication with each other or in interaction with each other, unless explicitly defined otherwise, the meaning of the terms described above in this application will be understood by those of ordinary skill in the art in view of the specific circumstances.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (9)
1. A preparation method of gentian extract is characterized in that: consists of the following compositions: water, gentian extract, butylene glycol, black sesame, wolfberry fruit, chinese angelica, rosemary essential oil, medicinal liquor, aromatic, additive and solubilizer;
the preparation method comprises the following steps:
s1, weighing gentian extract, butanediol, black sesame, medlar and angelica according to the required weight parts, mashing and mixing, adding water, heating and stirring for the first time, extracting residues, and performing first filtering treatment to obtain liquid medicine for the first treatment;
s2, weighing the essential oil and the solubilizer of the rosemary according to the preparation proportion, respectively pouring the essential oil and the solubilizer into the liquid medicine treated for the first time, carrying out first standing and cooling, adding the medicinal liquor, carrying out second heating and stirring, extracting residues, carrying out second filtering treatment to obtain the liquid medicine treated for the second time, and carrying out second standing and cooling;
s3, weighing the required weight parts of the aromatic and the additive according to the manufacturing proportion, stirring for the third time to obtain a finished liquid medicine product, standing and cooling for the third time, weighing the liquid medicine with the required weight, and finally packaging.
2. The method for preparing gentian extract according to claim 1, wherein: wherein the weight parts of the compositions are 100 to 1000 parts of water, 30 to 100 parts of gentian extract, 10 to 40 parts of butanediol, 5 to 10 parts of black sesame, 5 to 15 parts of medlar, 3 to 15 parts of angelica, 2 to 10 parts of rosemary essential oil, 10 to 50 parts of medicinal liquor, 1 to 3 parts of aromatic, 1 to 6 parts of additive and 1 to 10 parts of solubilizer respectively.
3. The method for preparing gentian extract according to claim 1, wherein: the aromatic is one or more of sandalwood rose type perfume, lemon mixture type perfume and mint type perfume, the additive is one or more of antidandruff agent, humectant, preservative, colorant and replenisher, and the solubilizer is one or more of polysorbate, polyoxyethylene ester, urea and short-chain benzenesulfonate.
4. The method for preparing gentian extract according to claim 1, wherein: the water is one or more of natural spring water, distilled water and snow mountain water, and the medicated liquor comprises mixture of Ginseng radix, poria and Atractylodis rhizoma.
5. The method for preparing gentian extract according to claim 1, wherein: the first heating time in the step S1 is 30-60min, the first heating temperature is 70-80 ℃, the second heating time in the step S2 is 40-80min, the second heating temperature is 80-100 ℃, and the third stirring time in the step S3 is 10-20min.
6. The method for preparing gentian extract according to claim 1, wherein: the first standing cooling time in the step S2 is 1-2h, the second standing cooling time in the step S2 is 1.5-2h, and the third standing cooling time in the step S3 is 2-3h.
7. A method for preparing gentian extract according to claim 3, wherein: and (3) reprocessing the extraction residues in the step S1 and the step S2, and extracting residual liquid in the extraction residues for storage to obtain the supplement.
8. The method for preparing gentian extract according to claim 1, wherein: the ratio of the fragrance to the additive is 1:2.
9. Use of the gentian extract of claim 8 in the preparation of cosmetic varieties with skin antibacterial anti-inflammatory repair effect.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310763971.0A CN116725919A (en) | 2023-06-27 | 2023-06-27 | Preparation method and application of gentian extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310763971.0A CN116725919A (en) | 2023-06-27 | 2023-06-27 | Preparation method and application of gentian extract |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116725919A true CN116725919A (en) | 2023-09-12 |
Family
ID=87909529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310763971.0A Pending CN116725919A (en) | 2023-06-27 | 2023-06-27 | Preparation method and application of gentian extract |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116725919A (en) |
-
2023
- 2023-06-27 CN CN202310763971.0A patent/CN116725919A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108272707B (en) | Chinese herbal medicine hair conditioner and preparation method thereof | |
| CN111714425B (en) | Shampoo composition for improving scalp and hair condition | |
| CN107137294A (en) | A kind of content in freckle cream and preparation method thereof | |
| CN110669598A (en) | Traditional Chinese medicine shampoo soap and preparation method thereof | |
| CN114533625A (en) | Anti-hair-loss hair-growing liquid and preparation method thereof | |
| CN113876683A (en) | Bird's nest plant composite smoothing toner | |
| CN113116800A (en) | Herbaceous plant anti-hair loss and hair growth liquid and preparation method thereof | |
| CN116392431B (en) | Composite anti-hair-loss hair-fixing composition, preparation method and application thereof | |
| CN112773748A (en) | Traditional Chinese medicine shampoo for treating seborrheic alopecia and application thereof | |
| CN111658558A (en) | Traditional Chinese medicine freckle-removing essence and preparation method thereof | |
| CN106726993A (en) | Chinese medicine hair cream and preparation method | |
| CN116725919A (en) | Preparation method and application of gentian extract | |
| CN110090179A (en) | A kind of scalp Essence with anti-dandruff and itching-relieving effect | |
| CN114983882A (en) | Hair nourishing liquid with alopecia preventing effect and preparation method thereof | |
| CN111481488B (en) | Formula and preparation method of plant shampoo capable of preventing white hair and blackening and strengthening hair | |
| CN104490611B (en) | A kind of natural hair conditioning effervescence granular or effervescent tablet and preparation method thereof | |
| CN111920714A (en) | Hair loss preventing and hair nourishing composition, hair loss preventing and hair nourishing liquid and preparation method thereof | |
| CN113679652A (en) | Facial mask with anti-inflammatory effect and preparation method thereof | |
| CN111631966A (en) | Essence for moistening and tendering skin and preparation method thereof | |
| CN112675272A (en) | Traditional Chinese medicine composition for preventing hair loss, shampoo and preparation method of shampoo | |
| CN104323958B (en) | A kind of natural sun cream extracting resin containing Radix Asteris | |
| CN112773879A (en) | Traditional Chinese medicine composition for growing and nourishing hair and preparation thereof | |
| CN110934807A (en) | Fleece-flower root essence for nourishing and blackening hair | |
| CN1212137C (en) | Hair follice activating liquid | |
| CN114848558B (en) | Hair-growing and blackening liquid capable of preventing hair loss and blackening white hair and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |