CN116585411A - Edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis and preparation method thereof - Google Patents
Edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis and preparation method thereof Download PDFInfo
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Abstract
The invention provides an edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing muscles and tendons, promoting blood circulation and removing blood stasis and a preparation method thereof. Comprises the following components in parts by weight: 5-10 parts of garden balsam, 5-10 parts of polygonum aviculare (commonly called red lycopodium clavatum), 4-8 parts of madder, 6-12 parts of cross-over, 3-6 parts of radix hedyotis, 6-12 parts of caulis spatholobi, 2-5 parts of radix angelicae pubescentis, 3-9 parts of rhizoma drynariae, 9-25 parts of radix puerariae, 9-15 parts of cherry and 2-3 parts of brown sugar. The edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis and the preparation method thereof are directly prepared into food products before the eyes of consumers, are convenient for patients to eat, have no more preparation processes in the later period, are low in cost, have obvious effects of relaxing tendons, activating collaterals, promoting blood circulation to remove blood stasis, treating rheumatic arthritis and treating arthralgia and myalgia, and can reduce the content of peripheral serum TNF-alpha of patients with the rheumatic arthritis, thereby improving the inflammatory state of diseases and controlling the disease activities.
Description
Technical Field
The invention relates to the field of traditional Chinese medicine formulas, in particular to an edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, activating blood circulation and removing blood stasis and a preparation method thereof.
Background
Rheumatic arthritis belongs to allergic diseases, is one of main manifestations of rheumatic fever, mostly causes diseases with acute fever and arthralgia, is typically manifested by mild or moderate fever, and is often caused by recurrent polyarthritis, the affected joints are mostly knee joints, ankle joints, shoulder joints, elbow joints and other large joints, the lesions are locally red, swelling, burning and extremely painful, a part of patients also have joint diseases at the same time, atypical patients only have joint pain and have no other manifestations of inflammation, acute inflammation generally subsides for 2-4 weeks without sequelae, but often repeatedly attacks, myocarditis and even left heart valve lesions can occur if the rheumatic activities affect the heart.
The rheumatic arthritis patients are treated by western medicines, the hormone in the western medicines only plays a role in relieving the illness state and cannot radically treat the illness state, the western medicines have side effects, are high in price and treatment cost, are not suitable for long-term administration, and the traditional Chinese medicines have slow treatment effect and low effects, and mainly take the traditional Chinese medicines for external application of the prepared Chinese medicinal ointment and decoction with water, so that the traditional Chinese medicines are inconvenient for the rheumatic arthritis patients to use.
Therefore, it is necessary to provide an edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis and a preparation method thereof to solve the technical problems.
Disclosure of Invention
The invention provides an edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis and a preparation method thereof, which aim to solve the problems of the background.
In order to solve the technical problems, the invention provides an edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis, which comprises the following components in parts by weight: 5-10 parts of garden balsam, 5-10 parts of polygonum aviculare, 4-8 parts of madder, 6-12 parts of Ningpo Yam rhizome, 3-6 parts of radix et rhizoma bovis seu Bubali, 6-12 parts of suberect spatholobus stem, 2-5 parts of radix angelicae pubescentis, 3-9 parts of rhizoma drynariae, 9-25 parts of radix puerariae, 9-15 parts of cherry and 2-3 parts of brown sugar.
A preparation method of an edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis comprises the following specific steps:
firstly, preparing materials, namely weighing garden balsam, polygonum aviculare, madder, climbing fern, radix et rhizoma oxtail, caulis spatholobi, radix angelicae pubescentis, rhizoma drynariae, radix puerariae, cherry and brown sugar according to parts by weight;
step two, the weighed raw materials are put into a pulverizer together to be pulverized into powder medicament with the fineness of 200-300 meshes;
step three, taking fresh kudzuvine root, drying and putting the fresh kudzuvine root into a pulverizer to pulverize into kudzuvine root powder with the fineness of 200-300 meshes;
step four, powder medicament and kudzuvine root powder are mixed according to the following ratio of 1:8, mixing uniformly to prepare medicinal powder.
An edible Chinese medicinal preparation with effects of dispelling pathogenic wind, removing dampness, relieving rigidity of muscles, promoting blood circulation, and removing blood stasis is prepared by mixing 20 g of the medicinal powder prepared in step four with boiled water, stirring into paste, and adding 5-10 g of brown sugar for administration three times per day.
The analysis of some of the components in the present invention is as follows:
the polygonum aviculare, also called red lycopodium clavatum, has slight pungent and cold nature, has the effects of dispelling wind and clearing heat, activating blood and detoxicating, and is mainly used for treating conjunctival congestion and swelling pain, glauber bone pain and rheumatic arthralgia.
The composition has the effects of dispelling pathogenic wind, removing dampness, dispelling cold, relieving pain, promoting blood circulation, dredging collaterals, eliminating phlegm, and relieving cough, and can be used for treating rheumatalgia, stomach cold pain, traumatic injury, cough and excessive phlegm.
Madder root, radix Rubiae, bitter in taste and cold in nature, has the effects of cooling blood, activating blood circulation, removing blood stasis and dredging channels, and is mainly used for treating bleeding due to heat, amenorrhea abdominal pain and traumatic injury.
The Chinese yam, also called lycopodium clavatum, has pungent taste and warm nature, has the effects of promoting blood circulation to remove blood stasis, diminishing inflammation and detoxifying, promoting tissue regeneration and bone growth, dispelling wind and eliminating dampness, and is mainly used for treating traumatic injury, fracture, sore and furuncle swelling and pain and rheumatic arthritis.
Radix seu herba Bulbophylli Ovis has sweet taste, pungent and warm nature, and has effects of nourishing liver, spleen and kidney channel, dispelling pathogenic wind and dampness, invigorating kidney and spleen, and relieving snake and canine toxin, and can be used for treating rheumatalgia, lumbago due to kidney deficiency, lumbar muscle strain, traumatic injury, contusion, dyspepsia, abdominal distention and pain, infantile malnutrition, snake bite, and canine bite.
Caulis Spatholobi has bitter taste, slightly sweet taste, warm nature, and has effects of nourishing liver, heart and kidney channels, promoting blood circulation, relaxing tendons, nourishing blood, and regulating menstruation, and can be used for treating rheumatalgia, numbness of limbs, paralysis of limbs, menoxenia, menstrual disorder, dysmenorrhea, amenorrhea, and leukopenia.
Radix Angelicae Pubescentis, has pungent and bitter taste and slightly warm nature, has effects of dispelling pathogenic wind, removing dampness, dispelling cold and relieving pain, and is mainly used for treating arthralgia due to wind-cold-dampness, and lumbago and gonalgia.
Rhizoma Drynariae, bitter in taste, warm in nature, enters liver and kidney meridians, has effects of tonifying kidney and strengthening bone, and relieving pain, and is used for treating lumbago due to kidney deficiency, tinnitus and deafness, loose teeth, traumatic injury and contusion, and tendons and bones fracture.
Radix Puerariae, sweet in flavor, pungent and cool in nature, has effects of relieving muscle and allaying fever, promoting eruption, promoting salivation to quench thirst, and invigorating yang and relieving diarrhea, and is mainly used for treating exterior syndrome fever, neck and back pain, measles, fever thirst, yin deficiency diabetes, heat diarrhea, spleen deficiency diarrhea.
Cherry has sweet taste and warm nature, has effects of inducing sweat, invigorating qi, dispelling pathogenic wind, promoting eruption, and can be used for treating numbness of limbs and rheumatic lumbago and leg diseases.
Compared with the related art, the edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing muscles and tendons, promoting blood circulation and removing blood stasis and the preparation method thereof have the following beneficial effects:
the invention provides an edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis and a preparation method thereof, wherein the edible traditional Chinese medicine is directly prepared into food before the eyes of consumers, is convenient for patients to eat, has no more preparation flow in the later period, has low cost, has obvious effects of relaxing tendons, activating collaterals, promoting blood circulation and removing blood stasis, treating rheumatic arthritis and treating arthralgia and myalgia, and can reduce the content of peripheral serum TNF-alpha of patients with rheumatic arthritis, thereby improving the inflammatory state of diseases and controlling the disease activities.
Detailed Description
The present invention will be further described with reference to the following embodiments.
Example 1
An edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis comprises the following components in parts by weight: 5 parts of garden balsam, 5 parts of polygonum aviculare, 4 parts of madder, 6 parts of cross-over yam, 3 parts of radix et rhizoma oxtail, 6 parts of suberect spatholobus stem, 2 parts of radix angelicae pubescentis, 3 parts of rhizoma drynariae, 9 parts of kudzuvine root, 9 parts of cherry and 2 parts of brown sugar.
Example two
An edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis comprises the following components in parts by weight: 10 parts of garden balsam, 10 parts of polygonum aviculare, 8 parts of madder, 12 parts of cross-over yam, 6 parts of radix et rhizoma oxtail, 12 parts of suberect spatholobus stem, 5 parts of radix angelicae pubescentis, 9 parts of rhizoma drynariae, 25 parts of kudzuvine root, 15 parts of cherry and 3 parts of brown sugar.
Example III
An edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis comprises the following components in parts by weight: 8 parts of garden balsam, 8 parts of polygonum aviculare, 6 parts of madder, 8 parts of cross-over yam, 5 parts of radix et rhizoma oxtail, 8 parts of suberect spatholobus stem, 3 parts of radix angelicae pubescentis, 5 parts of rhizoma drynariae, 12 parts of kudzuvine root, 12 parts of cherry and 3 parts of brown sugar.
Example IV
An edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis comprises the following components in parts by weight: 8 parts of garden balsam, 7 parts of polygonum aviculare, 6 parts of madder, 9 parts of cross-over yam, 4 parts of radix et rhizoma oxtail, 9 parts of suberect spatholobus stem, 4 parts of radix angelicae pubescentis, 6 parts of rhizoma drynariae, 18 parts of kudzuvine root, 12 parts of cherry and 2 parts of brown sugar.
A preparation method of an edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis comprises the following specific steps:
firstly, preparing materials, namely weighing garden balsam, polygonum aviculare, madder, climbing fern, radix et rhizoma oxtail, caulis spatholobi, radix angelicae pubescentis, rhizoma drynariae, radix puerariae, cherry and brown sugar according to parts by weight;
step two, the weighed raw materials are put into a pulverizer together to be pulverized into powder medicament with the fineness of 200-300 meshes;
step three, taking fresh kudzuvine root, drying and putting the fresh kudzuvine root into a pulverizer to pulverize into kudzuvine root powder with the fineness of 200-300 meshes;
step four, powder medicament and kudzuvine root powder are mixed according to the following ratio of 1:8, mixing uniformly to prepare medicinal powder.
An edible Chinese medicinal preparation with effects of dispelling pathogenic wind, removing dampness, relieving rigidity of muscles, promoting blood circulation, and removing blood stasis is prepared by mixing 20 g of the medicinal powder prepared in step four with boiled water, stirring into paste, and adding 5-10 g of brown sugar for administration three times per day.
Experimental cases
10 cases of rheumatic arthritis patients, 6 men and 4 women are selected; age 55-90 years, average age 76 years; the change of 1-12 weeks is observed by taking the traditional Chinese medicine of the invention after 3 months to 16 years of disease course.
Table 1 is a data table of ESR, CRP, DAS before and after treatment
According to table 1, joint disease activity score at 28 (DAS 28): the disease activity of the rheumatic arthritis patients is evaluated, and the DAS28 has the following calculation formula: DAS28 = 0.56×tjc +0.28×jc +0.7×lnesr +0.014×gh, where TJC: pain-relieving joint number; SJC: number of swollen joints; ESR: erythrocyte sedimentation rate (unit: mm/1 h); GH: the overall health status presented in the 100mm image analog scale. Recording data of 4 time points before treatment and at 4 th and 8 th 12 weeks of treatment, wherein a DAS28 calculator is adopted for calculation in research, and DAS28 is less than 2.6 for alleviation; DAS28 is more than or equal to 2.6 and less than or equal to 3.2, which is slight disease activity; DAS28 is more than 3.2 and less than or equal to 5.1, which is moderate disease activity; 5.1 > DAS28 is a severe disease event;
laboratory examination: recording blood sedimentation (ESR) and C-reactive protein (CRP) at 4 time points before treatment and after treatment for 4, 8 and 12 weeks, and simultaneously detecting blood routine, urine routine and liver and kidney functions for safety evaluation;
serum tumor necrosis factor-alpha (TNF-alpha) levels were measured pre-treatment and after 12 weeks of treatment using an enzyme-linked immunosorbent assay (EL isa) as shown in table 2.
Number of cases | Before treatment | After treatment |
10 | 126.63±21.18 | 85.84±17.57 |
Table 2 is a data sheet (ng/L) of TNF- α levels before and after treatment
According to the study, 10 patients are changed from severe disease activity to mild disease activity after 12 weeks by taking the traditional Chinese medicine, the clinical symptoms of the rheumatic arthritis patients can be obviously improved, ESR and CRP levels of the patients are improved, and DAS28 activity is reduced;
the study takes TNF-alpha as an observation object, and the result shows that after 12 weeks of treatment, the traditional Chinese medicine can reduce the content of the peripheral serum TNF-alpha of a patient with rheumatic arthritis, thereby improving the inflammatory state of the disease and controlling the disease activity.
The foregoing description is only illustrative of the present invention and is not intended to limit the scope of the invention, and all equivalent structures or equivalent processes or direct or indirect application in other related arts are included in the scope of the present invention.
Claims (3)
1. An edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis is characterized by comprising the following components in parts by weight: 5-10 parts of garden balsam, 5-10 parts of polygonum aviculare (commonly called red lycopodium clavatum), 4-8 parts of madder, 6-12 parts of cross-over, 3-6 parts of radix hedyotis, 6-12 parts of caulis spatholobi, 2-5 parts of radix angelicae pubescentis, 3-9 parts of rhizoma drynariae, 9-25 parts of radix puerariae, 9-15 parts of cherry and 2-3 parts of brown sugar.
2. The preparation method of the edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing tendons, promoting blood circulation and removing blood stasis according to claim 1 comprises the following specific steps:
firstly, preparing materials, namely weighing garden balsam, polygonum aviculare, madder, climbing fern, radix et rhizoma oxtail, caulis spatholobi, radix angelicae pubescentis, rhizoma drynariae, radix puerariae, cherry and brown sugar according to parts by weight;
step two, the weighed raw materials are put into a pulverizer together to be pulverized into powder medicament with the fineness of 200-300 meshes;
step three, taking fresh kudzuvine root, drying and putting the fresh kudzuvine root into a pulverizer to pulverize into kudzuvine root powder with the fineness of 200-300 meshes;
step four, powder medicament and kudzuvine root powder are mixed according to the following ratio of 1:8, uniformly mixing the materials in proportion to prepare medicinal powder;
step six, taking 20 g of the mixture each time, soaking the mixture in boiled water, stirring the mixture into paste, and adding a little brown sugar for taking.
3. The method for taking the edible traditional Chinese medicine for dispelling wind, removing dampness, relaxing muscles and tendons, promoting blood circulation and removing blood stasis according to claim 2, wherein 20 g of the medicine powder prepared in the fourth step is taken each time, soaked in boiled water and stirred into paste, and 5-10 g of brown sugar is added for taking three times a day.
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