CN116549437A - 大麻素类和n-酰基乙醇胺的组合 - Google Patents
大麻素类和n-酰基乙醇胺的组合 Download PDFInfo
- Publication number
- CN116549437A CN116549437A CN202310678191.6A CN202310678191A CN116549437A CN 116549437 A CN116549437 A CN 116549437A CN 202310678191 A CN202310678191 A CN 202310678191A CN 116549437 A CN116549437 A CN 116549437A
- Authority
- CN
- China
- Prior art keywords
- certain embodiments
- cannabinoid
- pharmaceutical composition
- salt
- thc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/348—Cannabaceae
- A61K36/3482—Cannabis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562154144P | 2015-04-29 | 2015-04-29 | |
| US62/154,144 | 2015-04-29 | ||
| CN201680024534.5A CN107530317A (zh) | 2015-04-29 | 2016-04-19 | 大麻素类和n‑酰基乙醇胺的组合 |
| PCT/IL2016/050414 WO2016174661A1 (en) | 2015-04-29 | 2016-04-19 | Combinations of cannabinoids and n-acylethanolamines |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680024534.5A Division CN107530317A (zh) | 2015-04-29 | 2016-04-19 | 大麻素类和n‑酰基乙醇胺的组合 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116549437A true CN116549437A (zh) | 2023-08-08 |
Family
ID=57199061
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310678191.6A Pending CN116549437A (zh) | 2015-04-29 | 2016-04-19 | 大麻素类和n-酰基乙醇胺的组合 |
| CN201680024534.5A Pending CN107530317A (zh) | 2015-04-29 | 2016-04-19 | 大麻素类和n‑酰基乙醇胺的组合 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680024534.5A Pending CN107530317A (zh) | 2015-04-29 | 2016-04-19 | 大麻素类和n‑酰基乙醇胺的组合 |
Country Status (12)
| Country | Link |
|---|---|
| US (7) | US11234956B2 (enExample) |
| EP (2) | EP3288553B1 (enExample) |
| JP (2) | JP6938465B2 (enExample) |
| CN (2) | CN116549437A (enExample) |
| AU (3) | AU2016254685B2 (enExample) |
| CA (1) | CA2984088C (enExample) |
| DK (1) | DK3288553T3 (enExample) |
| ES (1) | ES2935605T3 (enExample) |
| IL (2) | IL291864A (enExample) |
| MA (1) | MA41997A (enExample) |
| PL (1) | PL3288553T3 (enExample) |
| WO (1) | WO2016174661A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3288553T3 (pl) * | 2015-04-29 | 2023-03-20 | Scisparc Ltd | Połączenia kannabinoidów i n-acyloetanoloamin |
| WO2019136351A1 (en) * | 2018-01-05 | 2019-07-11 | Altus Labs, Llc | Personal care compositions |
| CA3126772A1 (en) * | 2018-01-29 | 2019-08-01 | Evero | Compositions and methods for treating obstructive sleep apnea |
| MX2020010424A (es) * | 2018-04-03 | 2021-01-15 | Pure Green Pharmaceuticals Inc | Comprimido o composicion que contiene n-acil etanolamina y cannabinoides. |
| WO2020160452A1 (en) * | 2019-02-01 | 2020-08-06 | Tess Ventures, Inc. | Combining serms, sarms, and cannabinoids for improving safety and efficacy of endocrine therapies |
| WO2020214569A1 (en) | 2019-04-15 | 2020-10-22 | Metagenics, Inc. | Novel hemp and pea formulation and its use |
| US20220211647A1 (en) * | 2019-04-23 | 2022-07-07 | SciSparc Ltd. | Compositions and methods for potentiating derivatives of 4-aminophenols |
| WO2020227440A1 (en) * | 2019-05-07 | 2020-11-12 | Ojai Energetics Pbc | Methods for optimized cannabinoid dosage determination |
| WO2020237247A1 (en) | 2019-05-23 | 2020-11-26 | India Globalization Capital, Inc. | Compositions and methods using cannabinoids for treating stammering/stutering and symptoms of tourette syndrome |
| EP4017486A4 (en) * | 2019-08-19 | 2023-09-20 | Buzzelet Development And Technologies Ltd | COMPOSITIONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND THEIR USES |
| EP3838346A1 (en) * | 2019-12-20 | 2021-06-23 | Chemo Research SL | Soft gelatin capsules comprising palmitoylethanolamide and alpha-lipoic acid |
| CN115297854A (zh) | 2020-01-10 | 2022-11-04 | 帕西拉制药股份有限公司 | 通过蛛网膜下腔给予缓释脂质体麻醉组合物治疗疼痛 |
| WO2021141959A1 (en) | 2020-01-10 | 2021-07-15 | Pacira Pharmaceuticals, Inc. | Treatment of pain by administration of sustained-release liposomal anesthetic compositions |
| US11273122B2 (en) | 2020-02-11 | 2022-03-15 | Therese Mainella | Combination of cannabis, derivatives thereof and additives in oral care compositions |
| EP4274573A4 (en) | 2021-01-11 | 2024-12-11 | Pacira Pharmaceuticals, Inc. | TREATMENT OF HIP PAIN WITH LIPOSOMAL SUSTAINED-RELEASE ANESTHESIA COMPOSITIONS |
| US20230000936A1 (en) * | 2021-06-30 | 2023-01-05 | Demetrix, Inc. | Alleviation of itching sensations using cannabinoid compounds |
| WO2023039419A2 (en) | 2021-09-08 | 2023-03-16 | Plantible Foods Inc. | Systems and methods for measuring mat density of aquatic biomass |
| WO2023200906A1 (en) | 2022-04-12 | 2023-10-19 | Shackelford Pharma Inc. | Treatment of seizure disorders |
| US12226610B2 (en) | 2022-11-03 | 2025-02-18 | Pacira Pharmaceuticals, Inc. | Treatment of pain associated with total knee arthroplasty with sustained-release liposomal anesthetic compositions |
| US11918565B1 (en) | 2022-11-03 | 2024-03-05 | Pacira Pharmaceuticals, Inc. | Treatment of post-operative pain via sciatic nerve block with sustained-release liposomal anesthetic compositions |
| WO2024124354A1 (en) * | 2022-12-16 | 2024-06-20 | Aima Inc. | Compositions and methods for treating or preventing pain or other disorders |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103826621A (zh) * | 2011-09-29 | 2014-05-28 | Gw药品有限公司 | 包含植物大麻素次大麻二酚(cbdv)和大麻二酚(cbd)的药物组合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU776414B2 (en) * | 1998-05-29 | 2004-09-09 | Neurosciences Research Foundation, Inc. | Control of pain with endogenous cannabinoids |
| US6949582B1 (en) * | 1999-05-27 | 2005-09-27 | Wallace Walter H | Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment |
| GB2394894B (en) * | 2002-11-04 | 2005-08-31 | G W Pharma Ltd | New use for pharmaceutical composition |
| US20090054526A1 (en) * | 2005-07-14 | 2009-02-26 | Hansen Harald S | Inhibitors of anorexic lipid hydrolysis for the treatment of eating disorders |
| GB2432312A (en) * | 2005-11-01 | 2007-05-23 | Gw Pharma Ltd | Pharmaceutical compositions for the treatment of pain |
| PL2475352T5 (pl) * | 2009-09-07 | 2019-02-28 | Epitech Group S.P.A. | Kompozycja zawierająca palmitoiloetanoloamid poddany ultramikronizacji |
| AT509000B1 (de) * | 2009-10-23 | 2012-12-15 | Rausch Peter | Wasserlösliche zubereitungen von cannabinoiden und cannabispräparaten und deren anwendungen |
| EP2719375A1 (en) * | 2012-10-10 | 2014-04-16 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Cannabinoids for the treatment of cancers dependent on hedgehog mechanisms |
| PL3288553T3 (pl) * | 2015-04-29 | 2023-03-20 | Scisparc Ltd | Połączenia kannabinoidów i n-acyloetanoloamin |
-
2016
- 2016-04-19 PL PL16786064.2T patent/PL3288553T3/pl unknown
- 2016-04-19 MA MA041997A patent/MA41997A/fr unknown
- 2016-04-19 AU AU2016254685A patent/AU2016254685B2/en active Active
- 2016-04-19 EP EP16786064.2A patent/EP3288553B1/en active Active
- 2016-04-19 CA CA2984088A patent/CA2984088C/en active Active
- 2016-04-19 US US15/570,118 patent/US11234956B2/en active Active
- 2016-04-19 CN CN202310678191.6A patent/CN116549437A/zh active Pending
- 2016-04-19 WO PCT/IL2016/050414 patent/WO2016174661A1/en not_active Ceased
- 2016-04-19 CN CN201680024534.5A patent/CN107530317A/zh active Pending
- 2016-04-19 IL IL291864A patent/IL291864A/en unknown
- 2016-04-19 JP JP2018507796A patent/JP6938465B2/ja active Active
- 2016-04-19 DK DK16786064.2T patent/DK3288553T3/da active
- 2016-04-19 ES ES16786064T patent/ES2935605T3/es active Active
- 2016-04-19 EP EP22215663.0A patent/EP4193993A3/en active Pending
-
2017
- 2017-10-24 IL IL255238A patent/IL255238B/en unknown
-
2019
- 2019-08-30 US US16/557,379 patent/US11207290B2/en active Active
- 2019-10-01 US US16/589,611 patent/US20200030281A1/en not_active Abandoned
- 2019-10-10 US US16/598,029 patent/US11197845B2/en not_active Expired - Fee Related
-
2021
- 2021-03-30 JP JP2021057991A patent/JP2021107401A/ja active Pending
- 2021-07-19 AU AU2021206784A patent/AU2021206784B2/en active Active
- 2021-08-27 US US17/459,583 patent/US20210393577A1/en active Pending
- 2021-11-12 US US17/524,942 patent/US20220071948A1/en not_active Abandoned
- 2021-11-12 US US17/525,046 patent/US20220071949A1/en active Pending
-
2023
- 2023-10-17 AU AU2023251426A patent/AU2023251426B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103826621A (zh) * | 2011-09-29 | 2014-05-28 | Gw药品有限公司 | 包含植物大麻素次大麻二酚(cbdv)和大麻二酚(cbd)的药物组合物 |
Non-Patent Citations (4)
| Title |
|---|
| COPPOLA, M ET AL.: "Palmitoylethanolamide: From endogenous cannabimimetic substance to innovative medicine for the treatment of cannabis dependence", 《MEDICAL HYPOTHESES》, vol. 81, no. 4, 31 October 2013 (2013-10-31), pages 619 - 622, XP028713525, DOI: 10.1016/j.mehy.2013.07.016 * |
| KIRSTEN R MU¨LLER-VAHL ET AL: "Treatment of Tourette syndrome with delta-9-tetrahydrocannabinol (DELTA9-THC): No influence on neuropsychological performance", 《NEUROPSYCHOPHARMACOLOGY》, vol. 28, no. 2, 28 February 2003 (2003-02-28), pages 384 - 388, XP055326007, DOI: 10.1038/sj.npp.1300047 * |
| PRISMIC PHARMACEUTICALS, INC: "THC and Opiates:"entourage effect "of prismic’s IP-ptotected palmitoylethanolamide drives new prescription drug strategy", pages 2, Retrieved from the Internet <URL:https://www.prnewswire.com/news-releases/thc-and-opiates-entourage-effect-of-prismics-ip-protected-palmitoylethanolamide-drives-new-prescription-drug-strategy-300029806.html> * |
| 刘胜等: "《精神外科学基础与临床》", 31 May 1999, 珠海出版社, pages: 146 - 147 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20251228 Address after: British Columbia, Canada Applicant after: Neurotherapy Laboratory Co. Country or region after: Canada Address before: Israel Tel Aviv Applicant before: Sespak Co.,Ltd. Country or region before: Israel |