CN116549437A - 大麻素类和n-酰基乙醇胺的组合 - Google Patents

大麻素类和n-酰基乙醇胺的组合 Download PDF

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Publication number
CN116549437A
CN116549437A CN202310678191.6A CN202310678191A CN116549437A CN 116549437 A CN116549437 A CN 116549437A CN 202310678191 A CN202310678191 A CN 202310678191A CN 116549437 A CN116549437 A CN 116549437A
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CN
China
Prior art keywords
certain embodiments
cannabinoid
pharmaceutical composition
salt
thc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202310678191.6A
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English (en)
Chinese (zh)
Inventor
A·施穆勒维茨
E·哈勃
E·布雷纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurotherapy Laboratory Co
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Sespak Co ltd
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Publication of CN116549437A publication Critical patent/CN116549437A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/658Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/348Cannabaceae
    • A61K36/3482Cannabis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pyrane Compounds (AREA)
CN202310678191.6A 2015-04-29 2016-04-19 大麻素类和n-酰基乙醇胺的组合 Pending CN116549437A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562154144P 2015-04-29 2015-04-29
US62/154,144 2015-04-29
CN201680024534.5A CN107530317A (zh) 2015-04-29 2016-04-19 大麻素类和n‑酰基乙醇胺的组合
PCT/IL2016/050414 WO2016174661A1 (en) 2015-04-29 2016-04-19 Combinations of cannabinoids and n-acylethanolamines

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201680024534.5A Division CN107530317A (zh) 2015-04-29 2016-04-19 大麻素类和n‑酰基乙醇胺的组合

Publications (1)

Publication Number Publication Date
CN116549437A true CN116549437A (zh) 2023-08-08

Family

ID=57199061

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202310678191.6A Pending CN116549437A (zh) 2015-04-29 2016-04-19 大麻素类和n-酰基乙醇胺的组合
CN201680024534.5A Pending CN107530317A (zh) 2015-04-29 2016-04-19 大麻素类和n‑酰基乙醇胺的组合

Family Applications After (1)

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CN201680024534.5A Pending CN107530317A (zh) 2015-04-29 2016-04-19 大麻素类和n‑酰基乙醇胺的组合

Country Status (12)

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US (7) US11234956B2 (enExample)
EP (2) EP3288553B1 (enExample)
JP (2) JP6938465B2 (enExample)
CN (2) CN116549437A (enExample)
AU (3) AU2016254685B2 (enExample)
CA (1) CA2984088C (enExample)
DK (1) DK3288553T3 (enExample)
ES (1) ES2935605T3 (enExample)
IL (2) IL291864A (enExample)
MA (1) MA41997A (enExample)
PL (1) PL3288553T3 (enExample)
WO (1) WO2016174661A1 (enExample)

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WO2019136351A1 (en) * 2018-01-05 2019-07-11 Altus Labs, Llc Personal care compositions
CA3126772A1 (en) * 2018-01-29 2019-08-01 Evero Compositions and methods for treating obstructive sleep apnea
MX2020010424A (es) * 2018-04-03 2021-01-15 Pure Green Pharmaceuticals Inc Comprimido o composicion que contiene n-acil etanolamina y cannabinoides.
WO2020160452A1 (en) * 2019-02-01 2020-08-06 Tess Ventures, Inc. Combining serms, sarms, and cannabinoids for improving safety and efficacy of endocrine therapies
WO2020214569A1 (en) 2019-04-15 2020-10-22 Metagenics, Inc. Novel hemp and pea formulation and its use
US20220211647A1 (en) * 2019-04-23 2022-07-07 SciSparc Ltd. Compositions and methods for potentiating derivatives of 4-aminophenols
WO2020227440A1 (en) * 2019-05-07 2020-11-12 Ojai Energetics Pbc Methods for optimized cannabinoid dosage determination
WO2020237247A1 (en) 2019-05-23 2020-11-26 India Globalization Capital, Inc. Compositions and methods using cannabinoids for treating stammering/stutering and symptoms of tourette syndrome
EP4017486A4 (en) * 2019-08-19 2023-09-20 Buzzelet Development And Technologies Ltd COMPOSITIONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND THEIR USES
EP3838346A1 (en) * 2019-12-20 2021-06-23 Chemo Research SL Soft gelatin capsules comprising palmitoylethanolamide and alpha-lipoic acid
CN115297854A (zh) 2020-01-10 2022-11-04 帕西拉制药股份有限公司 通过蛛网膜下腔给予缓释脂质体麻醉组合物治疗疼痛
WO2021141959A1 (en) 2020-01-10 2021-07-15 Pacira Pharmaceuticals, Inc. Treatment of pain by administration of sustained-release liposomal anesthetic compositions
US11273122B2 (en) 2020-02-11 2022-03-15 Therese Mainella Combination of cannabis, derivatives thereof and additives in oral care compositions
EP4274573A4 (en) 2021-01-11 2024-12-11 Pacira Pharmaceuticals, Inc. TREATMENT OF HIP PAIN WITH LIPOSOMAL SUSTAINED-RELEASE ANESTHESIA COMPOSITIONS
US20230000936A1 (en) * 2021-06-30 2023-01-05 Demetrix, Inc. Alleviation of itching sensations using cannabinoid compounds
WO2023039419A2 (en) 2021-09-08 2023-03-16 Plantible Foods Inc. Systems and methods for measuring mat density of aquatic biomass
WO2023200906A1 (en) 2022-04-12 2023-10-19 Shackelford Pharma Inc. Treatment of seizure disorders
US12226610B2 (en) 2022-11-03 2025-02-18 Pacira Pharmaceuticals, Inc. Treatment of pain associated with total knee arthroplasty with sustained-release liposomal anesthetic compositions
US11918565B1 (en) 2022-11-03 2024-03-05 Pacira Pharmaceuticals, Inc. Treatment of post-operative pain via sciatic nerve block with sustained-release liposomal anesthetic compositions
WO2024124354A1 (en) * 2022-12-16 2024-06-20 Aima Inc. Compositions and methods for treating or preventing pain or other disorders

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Publication number Publication date
US20200038367A1 (en) 2020-02-06
CN107530317A (zh) 2018-01-02
EP3288553A4 (en) 2018-12-26
WO2016174661A1 (en) 2016-11-03
CA2984088A1 (en) 2016-11-03
IL291864A (en) 2022-06-01
US11197845B2 (en) 2021-12-14
US20180078523A1 (en) 2018-03-22
AU2023251426A1 (en) 2023-11-09
AU2023251426B2 (en) 2025-11-27
MA41997A (fr) 2021-03-31
EP4193993A3 (en) 2023-07-19
US20200030281A1 (en) 2020-01-30
ES2935605T3 (es) 2023-03-08
US20220071948A1 (en) 2022-03-10
JP2021107401A (ja) 2021-07-29
AU2021206784B2 (en) 2023-07-20
US11234956B2 (en) 2022-02-01
JP6938465B2 (ja) 2021-09-22
JP2018514589A (ja) 2018-06-07
IL255238B (en) 2022-05-01
AU2021206784A1 (en) 2021-08-12
EP4193993A2 (en) 2023-06-14
US11207290B2 (en) 2021-12-28
EP3288553B1 (en) 2022-12-28
DK3288553T3 (da) 2023-01-23
EP3288553A1 (en) 2018-03-07
CA2984088C (en) 2024-04-09
US20210393577A1 (en) 2021-12-23
PL3288553T3 (pl) 2023-03-20
AU2016254685B2 (en) 2021-04-22
AU2016254685A1 (en) 2017-11-09
US20220071949A1 (en) 2022-03-10
IL255238A0 (en) 2017-12-31
US20200022946A1 (en) 2020-01-23

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Effective date of registration: 20251228

Address after: British Columbia, Canada

Applicant after: Neurotherapy Laboratory Co.

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Address before: Israel Tel Aviv

Applicant before: Sespak Co.,Ltd.

Country or region before: Israel