CN116348132A - 基于合成的被修饰的痘苗安卡拉(smva)的冠状病毒疫苗 - Google Patents

基于合成的被修饰的痘苗安卡拉(smva)的冠状病毒疫苗 Download PDF

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CN116348132A
CN116348132A CN202180059838.6A CN202180059838A CN116348132A CN 116348132 A CN116348132 A CN 116348132A CN 202180059838 A CN202180059838 A CN 202180059838A CN 116348132 A CN116348132 A CN 116348132A
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smva
protein
antigen
cov
sars
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唐·J·戴蒙德
费利克斯·乌索
弗拉维亚·奇乌佩西
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City of Hope
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
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    • C07K2319/00—Fusion polypeptide
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CN202180059838.6A 2020-05-17 2021-05-17 基于合成的被修饰的痘苗安卡拉(smva)的冠状病毒疫苗 Pending CN116348132A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063026127P 2020-05-17 2020-05-17
US63/026,127 2020-05-17
US202063044033P 2020-06-25 2020-06-25
US63/044,033 2020-06-25
US202063113810P 2020-11-13 2020-11-13
US63/113,810 2020-11-13
US202163161371P 2021-03-15 2021-03-15
US63/161,371 2021-03-15
PCT/US2021/032821 WO2021236550A1 (en) 2020-05-17 2021-05-17 Synthetic modified vaccinia ankara (smva) based coronavirus vaccines

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CN116348132A true CN116348132A (zh) 2023-06-27

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US (2) US20230323389A1 (enExample)
EP (1) EP4153228A4 (enExample)
JP (2) JP7788403B2 (enExample)
KR (1) KR20230012583A (enExample)
CN (1) CN116348132A (enExample)
AU (1) AU2021276265A1 (enExample)
BR (1) BR112022023173A2 (enExample)
CA (1) CA3183016A1 (enExample)
IL (1) IL298210A (enExample)
MX (1) MX2022014387A (enExample)
WO (1) WO2021236550A1 (enExample)

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EP4153228A4 (en) 2020-05-17 2024-07-10 City of Hope CORONAVIRUS VACCINES BASED ON SYNTHETIC MODIFIED ANKARA VACCINE (SMVA) VIRUS
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US20250235527A1 (en) * 2021-11-17 2025-07-24 City Of Hope Synthetic modified vaccinia ankara (smva) based coronavirus vaccines
CN117384864A (zh) * 2022-07-11 2024-01-12 清华大学 表达SARS-CoV-2 Omicron Spike蛋白的重组腺病毒及其应用
EP4558171A1 (en) * 2022-07-22 2025-05-28 City of Hope Synthetic modified vaccinia ankara vaccines to stimulate orthopox and monkeypox virus immunity
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BR112022023173A2 (pt) 2022-12-27
WO2021236550A1 (en) 2021-11-25
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JP7788403B2 (ja) 2025-12-18
US12584146B2 (en) 2026-03-24
EP4153228A1 (en) 2023-03-29
MX2022014387A (es) 2023-04-11
JP2023526073A (ja) 2023-06-20
US20250313858A1 (en) 2025-10-09
KR20230012583A (ko) 2023-01-26
AU2021276265A1 (en) 2022-12-08
US20230323389A1 (en) 2023-10-12
IL298210A (en) 2023-01-01
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