CN115397998A - 由天然或合成dna产生的基于痘病毒的载体及其用途 - Google Patents
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Abstract
公开了从天然衍生的，化学合成的DNA片段，或天然衍生的和化学合成的DNA片段的组合产生基于痘病毒的载体或基于重组痘病毒的载体的方法。将编码一个或多个抗原，亚单位或其片段的一个或多个DNA序列或其他异源基因序列插入一个或多个DNA片段的一个或多个痘病毒插入位点中。该方法包括用一个或多个环状或线性DNA片段转染宿主细胞，使得痘病毒或重组痘病毒在该宿主细胞中重构，该重构的痘病毒或重组痘病毒包含想要的痘病毒的基因组。还公开了通过本技术产生的痘病毒或重组痘病毒及其用途。
Description
优先权声明
本申请要求于2020年2月3日提交的美国临时专利申请号62/969,628，和于2020年11月13日提交的美国临时专利申请号63/113,803的优先权，其内容通过引用整体并入本文。
序列表
本申请包含以ASCII格式电子提交并通过引用整体并入本文的序列表。所述ASCII副本创建于2021年2月2日，名为8200WO00_SequenceListing.txt，大小为652千字节。
背景
痘病毒是大型双链包膜DNA病毒，通过编码其自身的DNA转录和复制酶，在受感染细胞的细胞质中完全复制20，27。医学史上最伟大的成就之一是通过大规模疫苗接种具有复制能力的减毒痘苗病毒疫苗株根除天花(天花病毒)的病原体。痘苗病毒被用作研究痘病毒复制的原型成员，并已被进一步开发以生成重组疫苗和溶瘤剂。
被修饰的痘苗安卡拉(MVA)是一种高度减毒的正痘病毒，自其亲本株绒毛膜尿囊痘苗安卡拉(CVA)在鸡胚成纤维细胞(CEF)上通过570次传代衍生而来1。由于减毒过程，MVA获得了六个主要的基因组缺失(Del1-6)以及多个较短的缺失，插入，和点突变，导致基因片段化，截断，短内部缺失，和氨基酸替换2。虽然所有这些突变均可能导致MVA的高度减毒表型，但与MVA组装缺陷相关联的精确遗传决定因素仍然不清楚2，3。MVA严重限制了宿主细胞的嗜性(tropism)，仅允许在禽类细胞中进行生产性组装，例如，CEF和幼仓鼠肾(BHK)细胞，而在人和大多数其他哺乳动物细胞中，MVA组装由于病毒组装的后期阻滞而失败4，5。虽然为非病原和高度减毒，但MVA仍保持出色的免疫原性，如多个动物模型和人所示6，7。在根除天花运动的后期阶段，MVA被用作德国120,000多人的基于具有复制能力的痘苗的疫苗的启动载体，并且没有报告任何不良事件8。在过去的几十年中，MVA已被开发为一种独立的(stand-alone)天花疫苗，目前美国(US)政府正在寻求将其作为更安全的替代物以代替已有的基于痘苗的疫苗库存，作为天花爆发的预防对策9-11。FDA于2019年9月24日批准了商品名为Jynneos(巴伐利亚北欧)的MVA以预防天花和猴痘。此前，使用商品名Imvamune的同一MVA疫苗在欧洲被批准为天花疫苗。
所有目前使用的MVA载体或其衍生物均由学术，商业，或政府实体许可或拥有，这大大限制了它们用于开发基于MVA的疫苗载体。因此，需要开发用于多种研究，预防，和治疗用途的替代MVA载体。此外，迫切需要新技术来加速开发用于病原体制备和疾病预防的重组痘病毒载体。
发明内容
在一个方面，本公开涉及产生痘病毒载体或重组痘病毒载体的方法。该方法需要将一个或多个DNA片段转染入宿主细胞的步骤，其中该一个或多个DNA片段包含想要的痘病毒的整个基因组DNA序列，使得痘病毒在该宿主细胞中重构。在某些实施例中，将两个或更多个DNA片段共转染入宿主细胞，每个DNA片段包含痘病毒基因组的部分序列，使得两个或更多个DNA片段在宿主细胞中重构时通过同源重组顺序组装并包含痘病毒基因组的全长序列。在某些实施例中，该方法还需要在转染一个或多个DNA片段之前，期间，或之后用辅助病毒感染该宿主细胞以启动该一个或多个DNA片段的转录。在某些实施例中，该辅助病毒是禽痘病毒(FPV)，绵羊纤维瘤病毒，痘苗病毒，或牛痘病毒。在某些实施例中，该一个或多个DNA片段在转染之前被环化或以环状形式转染入宿主细胞。在某些实施例中，将一个或多个DNA片段克隆到质粒或细菌人工染色体(BAC)载体中。在某些实施例中，该一个或多个DNA片段在共转染之前线性化或以线性化形式转染入宿主细胞。在某些实施例中，该一个或多个DNA片段是天然衍生的，化学合成的，或天然衍生的和化学合成的DNA片段的组合。在某些实施例中，该痘病毒基因组序列包含被修饰的痘苗安卡拉(MVA)登录号#U94848或#AY603355的序列。在某些实施例中，该痘病毒基因组序列包含痘苗病毒基因组的序列。在某些实施例中，两个相邻DNA片段具有重叠序列以有助于同源重组。在某些实施例中，该重叠序列的长度在约100bp和约5000bp之间。在某些实施例中，该一个或多个DNA片段还包含反向末端重复(ITR)区。在某些实施例中，该一个或多个DNA片段还包含痘病毒末端发夹环(HL)序列，痘病毒基因组解析(CR)序列，或两者，其中该HL或该CR序列作为单链或双链DNA序列以正义或反义方向添加至该DNA片段的一端或两端。在某些实施例中，该一个或多个DNA片段还包含一个或多个HL序列和一个或多个CR序列。在某些实施例中，每个HL序列在该HL序列的两端的侧翼为两个CR序列。在某些实施例中，其中仅该一个或多个DNA片段的子集包含该HL或CR序列。在某些实施例中，该一个或多个DNA片段还包含编码一个或多个抗原，亚单位，或其片段的一个或多个DNA序列或其他异源DNA序列。在某些实施例中，两个或更多个DNA片段包含相同抗原，亚单位或其片段DNA序列或相同异源DNA序列。在某些实施例中，两个或更多个DNA片段包含不同抗原，亚单位，或其片段的DNA序列或其他异源DNA序列。在某些实施例中，抗原，亚单位，或其片段的DNA序列或其他异源DNA序列被密码子优化以在宿主细胞中表达。在某些实施例中，该一个或多个DNA片段还包含抗原，亚单位，或其片段的DNA序列或其他异源DNA序列上游的病毒启动子，抗原，亚单位，或其片段的DNA序列或其他异源DNA序列下游的转录终止信号，或两者。在某些实施例中，编码抗原，亚单位，或其片段的DNA序列或其他异源DNA序列被插入一个或多个痘病毒插入位点中，如基因间区域，非必需基因和区域，和缺失位点。
在另一个方面，本文公开了表达系统，其包含：(i)包含想要的痘病毒的整个基因组的单个DNA片段，或各自包含想要的痘病毒的基因组的部分序列的两个或更多个DNA片段，使得当在共转染后转移入宿主细胞时，该两个或更多个DNA片段顺序组装并包含痘病毒基因组的全长序列且能够重构痘病毒，和(ii)编码一个或多个抗原，亚单位，或其片段的一个或多个DNA序列或其他异源DNA序列被插入痘病毒的一个或多个插入位点中，其中抗原或其亚单位或其他异源DNA序列在一个或多个痘病毒DNA片段转染和痘病毒重构后在宿主细胞中表达。在某些实施例中，该一个或多个DNA片段在转染之前被环化或以环状形式转染入宿主细胞。在某些实施例中，将一个或多个DNA片段克隆到质粒或BAC载体中。在某些实施例中，该一个或多个DNA片段在转染之前线性化或以线性化形式转染入宿主细胞。在某些实施例中，该一个或多个DNA片段是天然衍生的，化学合成的，或天然衍生的和化学合成的DNA片段的组合。在某些实施例中，该痘病毒的基因组序列包含MVA登录号#U94848或#AY603355的序列。在某些实施例中，两个相邻DNA片段具有重叠序列以有助于同源重组。在某些实施例中，该重叠序列的长度在约100bp和约5000bp之间。在某些实施例中，该一个或多个DNA片段还包含反向末端重复(ITR)区。在某些实施例中，该一个或多个DNA片段还包含痘病毒末端发夹环(HL)序列，痘病毒基因组解析(CR)序列，或两者，其中该HL或该CR序列作为单链或双链DNA序列以正义或反义方向添加至该DNA片段的一端或两端。在某些实施例中，该一个或多个DNA片段还包含一个或多个HL序列和一个或多个CR序列。在某些实施例中，每个HL序列在该HL序列的两端的侧翼为两个CR序列。在某些实施例中，仅该一个或多个DNA片段的子集包含该HL或CR序列。在某些实施例中，该一个或多个DNA片段还包含编码抗原，亚单位或其片段的DNA序列或其他异源DNA序列上游的病毒启动子，编码抗原，亚单位或其片段的DNA序列或其他异源DNA序列下游的转录终止信号，或两者。在某些实施例中，编码一个或多个抗原，亚单位或其片段的DNA序列或其他异源DNA序列被插入一个或多个痘病毒插入位点中。
在另一个方面，本文公开了用于预防或治疗癌症或感染性疾病的疫苗组合物，其包含：(i)包含想要的痘病毒的整个基因组的单个DNA片段，或各自包含想要的痘病毒的基因组的部分序列的两个或更多个DNA片段，使得当在共转染后转移入宿主细胞时，该两个或更多个DNA片段顺序组装并包含痘病毒基因组的全长序列且能够重构痘病毒，和(ii)编码一个或多个抗原，亚单位，或其片段的一个或多个DNA序列或其他异源DNA序列被插入痘病毒的一个或多个插入位点中，其中抗原，亚单位或其片段，或其他异源DNA序列在一个或多个DNA片段转染和痘病毒重构后在宿主细胞中表达。在某些实施例中，抗原，亚单位或其片段，或其他异源DNA序列被插入一个或多个痘病毒插入位点中。在某些实施例中，疫苗组合物还包含药学上可接受的载体，佐剂，添加剂，或其组合。
在又一个方面，本文公开了预防或治疗受试者的癌症或病毒感染的方法，包括向该受试者施用预防或治疗有效量的疫苗组合物，其中该疫苗包含：(i)包含想要的痘病毒的整个基因组的单个DNA片段，或各自包含想要的痘病毒的基因组的部分序列的两个或更多个DNA片段，使得当在共转染后转移入宿主细胞时，该两个或更多个DNA片段顺序组装并包含痘病毒基因组的全长序列且能够重构痘病毒，和(ii)编码一个或多个抗原，亚单位或其片段的一个或多个DNA序列或其他异源DNA序列被插入痘病毒的一个或多个插入位点中，其中抗原，亚单位，或其片段，或其他异源DNA序列在一个或多个DNA片段转染和痘病毒重构后在宿主细胞中表达。在某些实施例中，抗原，亚单位，或其片段，或其他异源DNA序列被插入一个或多个痘病毒插入位点中。
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图1A-1C示出了sMVA构建的设计。图1A：MVA基因组示意图。MVA基因组的长度大约为178kbp，且包含侧翼为大的～9.6kbp长的反向末端重复(ITR)的内部独特区(UR)。图1B：sMVA片段示意图。三个sMVA片段中的每一个的长度大约为60kbp。sMVA片段1(F1)包含MVA基因组左部分的序列，包括左ITR；sMVA片段2(F2)包含MVA基因组中间部分的序列；sMVA片段3(F3)包含MVA基因组右部分的序列，包括右ITR。sMVAF1和F2以及sMVA F2和F3共享用于同源重组的～3kbp重叠序列(点虚线交叉线)。标示了常用MVA插入位点的近似位置，包括sMVAF1内的Del2，IGR44/45(44/45)，和IGR64/65(69/70)，sMVA F2内的IGR69/70(69/70)和TK插入位点，和sMVA F3内的Del3。图1C：末端HL和CR序列的示意图。每个sMVA片段在两端包含序列组合物，该序列组合物包含MVA末端HL和侧翼CR序列的双链体拷贝，以促进基因组的解析和包装。如所示在每个sMVA片段的两端包括SfiI和FseI限制性位点，以通过酶消化从具有或不具有末端CR/HL/CR序列的细菌载体骨架(pCCI-Brick)释放片段。
图2示出了sMVA的重构。描绘了使用如图1所示的三个sMVA片段(F1-F3)生成sMVA(sMVA)的示意图。将三个sMVA片段稳定地保持在大肠杆菌中，然后从细菌中分离出来，并通过转染将其作为环状或线性化DNA分子转移入MVA容许的BHK或CEF细胞。随后用禽痘病毒(FPV)作为辅助病毒感染被转染的细胞，以启动MVA基因组转录和复制，从而重构病毒形式的sMVA。
图3描绘了具有一个抗原的重组sMVA的构建。示意图示出了构建具有一个引入的抗原序列，异源基因序列，或其他基因组改变的重组sMVA(rsMVA)的示例。使用线性PCR衍生的产物或其他形式的线性DNA构建体，通过大肠杆菌中的细菌重组方法，将抗原或异源基因序列(黑色圆圈)插入F2(或其他sMVA片段之一(F1或F3))的MVA基因组序列中。被修饰的sMVA片段F1和未被修饰的sMVA片段F2和F3从大肠杆菌中分离出来，并以环状或线性化形式共转染入FPV感染的BHK或CEF细胞，以启动表达一个抗原或异源基因序列的rsMVA的重构。Nucl.＝细胞核。
图4说明了具有三个抗原的重组sMVA的构建。示意图示出了生成具有3个引入的抗原序列，异源基因序列，或其他基因组改变的重组sMVA(rsMVA)的示例。使用线性PCR衍生的产物或其他形式的线性DNA构建体，通过大肠杆菌中的细菌重组技术，将抗原或异源基因序列(以正方形，圆形，或矩形示出)插入三个sMVA片段(F1-F3)的每一个中。被修饰的F1，F2，和F3 sMVA片段从大肠杆菌中分离出来，并以环状或线性化形式共转染入容许的BHK或CEF细胞，其中表达三个抗原或异源基因序列的rsMVA病毒在FPV作为辅助病毒的存在下重构。Nucl.＝细胞核。
图5说明了sMVA重构过程。示意图示出了使用三个sMVA片段(F1-F3)或其被修饰形式的sMVA或rsMVA的组织培养重构过程的示例。以6孔组织培养形式接种的BHK细胞与三个sMVA片段(未被修饰，被修饰，或其组合)共转染，随后用FPV作为辅助病毒感染，以启动sMVA片段的转录和复制，从而启动sMVA病毒的重构。如所示每隔一天(在转染/感染后2，4，和6天(dpt/i))将被转染/感染的BHK细胞转移入更大的组织培养形式，以促进sMVA重构。在第2天和第4天细胞转移后可以检测到斑块形成和进展，从而在第6天转移后90-100％的BHK细胞在7或8dpt/i被感染。
图6A-6B示出了sMVA感染性分析。图6A是示出了在感染后(dpi)1天被sMVA或MVANIH克隆1感染的BHK细胞单层中5个单个斑块的代表性明场显微镜图像的斑块分析。图6B示出了感染的进展。所示是在1，2，和3dpi被sMVA或MVA NIH克隆1感染的BHK细胞单层的代表性明场显微镜图像。将假感染(未被感染)的BHK细胞单层作为对照进行分析。通过痘苗病毒B5R蛋白的免疫染色观察斑块和被感染区域。
图7A-7L示出了重构的sMVA的PCR分析。BHK细胞以MOI 5被从三个sMVA片段(F1-F3)重构的sMVA病毒或MVA NIH克隆1感染，并通过PCR评估了从被感染的BHK细胞提取的DNA。将从假感染(未被感染)的BHK细胞(BHK)提取的DNA以及仅H2O(Ctrl)作为对照进行分析。PCR分析包括反向末端重复(ITR)的序列检测(图7A)；位于sMVA F1衍生的DNA的从左ITR过渡至内部独特区(LITR/UR)(图7B)和MVA缺失2位点(Del2)(图7C)；位于sMVA F2衍生的DNA的MVA 69R和70L之间的基因间区域(IGR)(IGR69/70)(图7D)；位于sMVAF3衍生的DNA的MVA缺失3位点(Del3)(图7E)和从内部UR过渡至右ITR(UR/RITR)(图7F)；sMVA F1和F2(F1/F2)(图7G)以及F2和F3(F2/F3)(图7H)的重组位点的重构；和包含对MVA株Antoine特异的五个核苷酸多态性(P0lym.1，2，3，4/5)(图7I-7L)的MVA基因组位置。预期的PCR产物由每个小图右侧的箭头标示。PCR产物的预期大小在每个小图下方的括号中给出。
图8示出了用单荧光标志物重构sMVA。所示是BHK细胞单层使用未被修饰的sMVA片段F1和F3以及具有插入的红色荧光蛋白(RFP)标志物的被修饰的sMVA片段F2(F2-RFP)在转染/感染后(dpt/i)6天和7天的代表性免疫荧光和明场显微镜图像。这些片段的sMVA重构过程如图5所示，FPV被用作辅助病毒。假转染/感染的BHK细胞单层作为对照进行分析。
图9示出了用双荧光标志物重构sMVA。所示是BHK细胞单层使用未被修饰的sMVA片段F1，具有插入的红色荧光蛋白(RFP)标志物的被修饰的sMVA片段F2(F2-RFP)，和具有插入的蓝色荧光蛋白(BFP)标志物的被修饰的sMVA片段F3(F3-BFP)在转染/感染后(dpt/i)6天和7天的代表性免疫荧光和明场显微镜图像。这些片段的sMVA重构过程如图5所示，FPV被用作辅助病毒。假转染/感染的BHK细胞单层作为对照进行分析。
图10A-10H说明了rsMVA HCMV载体构建的多个示例。所示是使用sMVA片段F1-F3生成rsMVA载体的示例，该rsMVA载体具有基于五聚体复合物(PC；包括UL128，UL130，UL131A，gH，和gL)的五个亚单位，糖蛋白B(gB)，磷蛋白65(pp65)，和/或即早(immediately-early)蛋白1和2(IE1和IE2)的被插入的HCMV抗原序列。HCMV抗原序列如所示分开地或组合地作为2A连接的多顺反子表达构建体插入不同的MVA插入位点中，包括MVA缺失3(Del3)位点或开放阅读框044/045(44/45)，064/065(64/65)，或069/070(69/70)之间的基因间区域。提供了表达全部PC亚单位(sMVA-PC1(图10A)和sMVA-PC2(图10B))，全部PC亚单位连同gB和pp65(sMVA-7Ag1(图10C)和sMVA-7Ag2(图10D))，或全部PC亚单位，gB，和pp65连同IE1/IE2抗原(sMVA-8Ag1/2(图10E-10F))和sMVA-9Ag2(图10G-10H))的rsMVA载体的示例。mH5代表痘苗修饰的H5启动子，ITR代表反向末端重复。
图11A-11B示出了sMVA特性。图11A：PCR分析。被sMVA感染的CEF由FPV HP1.441(sMVA hp)或来自两个独立病毒重构体(sMVA tv1和sMVA tv2)的TROVAC衍生，通过PCR研究了几个MVA基因组位置(ITR序列，左或右ITR过渡至内部独特区(左ITR/UR；UR/右ITR)，Del2，IGR69/70，和Del3插入位点，以及F1/F2和F2/F3重组位点)和缺失BAC载体序列。用wtMVA感染和未被感染的细胞，无样本(假)，或用MVABAC进行PCR反应作为对照。图11B：限制性片段长度分析。通过KpnI和XhoI限制性酶消化比较了从超纯化的sMVA(sMVA tv1和sMVAtv2)或wtMVA病毒分离的病毒DNA。
图12A-12D示出了sMVA复制特性。将由FPV HP1.441(sMVA hp)或来自两个独立病毒重构体(sMVA tv1和sMVA tv2)的TROVAC衍生的sMVA的复制特性与wtMVA进行了比较。图12A：病毒病灶。使用抗痘苗多克隆抗体(αVAC)对被重构的sMVA病毒或wtMVA以低感染复数(MOI)感染的CEF进行免疫染色。图12B：复制动力学。BHK或CEF细胞以0.02MOI被sMVA或wtMVA感染，并测定了感染后24和48小时CEF上接种物和被感染细胞的病毒滴度。应用了Geisser-Greenhouse校正的混合效应模型；在感染后24和48小时，组间差异不显著。图12C：病毒病灶大小分析。BHK或CEF细胞单层以0.002MOI被sMVA或wtMVA感染，并在感染后24小时用αVAC抗体免疫染色后测定了病毒病灶面积。图12D：宿主细胞范围分析。多个人细胞系(HEK293，A549，143b，和HeLa)，CEF，或BHK细胞以0.01MOI被sMVA或wtMVA感染，并测定了感染后48小时CEF上病毒滴度。点虚线表示基于0.01MOI计算的接种物的病毒滴度。图12C-12D中的组间差异使用单向ANOVA计算，然后进行Tukey(2C)或Dunnett(2D)多重比较检验。ns＝不显著。
图13A-13D显示了sMVA的体内免疫原性。通过体外分析将由FPV HP1.441(sMVAhp)或来自两个独立病毒重构体(sMVA tv1和sMVA tv2)的TROVAC衍生的sMVA与wtMVA进行了比较。C57BL/6小鼠每隔三周用低(1x107PFU)或高(5x107PFU)剂量的sMVA或wtMVA免疫两次。假免疫的小鼠用作对照。图13A：结合抗体。在第一次和第二次免疫后通过ELISA测量了由sMVA或wtMVA刺激的MVA特异性结合抗体(IgG滴度)。图13B：NAb反应。在针对表达GFP标志物的重组wtMVA的加强免疫后，测量了由sMVA或wtMVA诱导的MVA特异性NAb滴度。图13C-13D：T细胞反应。在使用B8R免疫显性肽进行离体抗原刺激后，通过流式细胞术测量了两次免疫后由sMVA或wtMVA诱导的MVA特异性IFNγ，TNFα，IL-4，和IL-10分泌性CD8+(13C)和CD4+(13D)T细胞反应。使用Tukey多重比较检验的单向ANOVA评估了组间差异。ns＝不显著。
图14A-14D显示了sMVA的体内免疫原性。通过体外分析将由FPV株HP1.441(sMVAhp)或来自两个独立病毒重构体(sMVA tvl和sMVA tv2)的FPV株TROVAC衍生的sMVA与wtMVA进行了比较。C57BL/6小鼠(N＝4)在三周间隔内用低(1x107PFU)或高(5x107PFU)剂量的sMVA或wtMVA免疫两次。假免疫的小鼠用作对照。图14A：结合抗体。所示是在接受sMVA或wtMVA的小鼠中第一次和第二次免疫后通过ELISA测量的不同血清稀释的MVA特异性结合抗体(IgG滴度)在450nm处的吸光度。图14B：NAb反应。在针对表达GFP标志物的wtMVA的加强免疫后，测量了由sMVA或wtMVA诱导的MVA特异性NAb滴度。所示是在不同血清稀释下以平方像素(pix2x103)表示的被感染细胞的所测量GFP面积。图14C-14D：T细胞反应。在使用痘苗A19L免疫显性肽进行离体抗原刺激后，通过流式细胞术测量了用sMVA或wtMVA进行两次免疫后表达IFNγ，TNFα，IL-4，和IL-10的MVA特异性CD8+(14C)和CD4+(14D)T细胞。使用Tukev多重比较检验的单向ANOVA评估了组间差异。ns＝不显著。
发明详述
本文公开了从环化或线性化的天然衍生或化学合成的DNA产生基于痘病毒的载体和重组痘病毒载体的方法。本文提供了从环化合成DNA片段以及表达一个或多个异源基因序列(包括荧光标志物或感染性疾病和癌症抗原)的重组sMVA(rsMVA)产生完全合成形式的MVA(sMVA)的具体示例。
由于MVA除了其通用的(versatile)表达系统和容纳外源DNA序列(高达30kbp)的大容量外，还具有出色的安全性1，因此MVA被广泛用于开发针对感染性疾病和癌症的重组疫苗载体7，12，13。MVA一直致力于开发癌症治疗的不同疫苗策略14，15以及多种疫苗方法以预防人巨细胞病毒(HCMV)感染16-18，这是新生儿永久性出生缺陷和移植接受对象并发症的常见原因19。其中一些疫苗已完成临床I期或II期评估14，17。作为痘病毒家族的一员，MVA完全在被感染细胞的细胞质中复制，为转录和DNA复制提供其自身酶1，20。尽管MVA病毒的产生由于哺乳动物细胞中组装的后期阻滞而失败，但是MVA可以有效感染大多数哺乳动物细胞，包括人细胞，并启动稳健的基因表达和DNA复制，使MVA成为体外和体内有效递送和表达外源抗原的理想载体1，5。最常用的生成MVA重组体的方法是基于使用转移质粒的所谓转染/感染方法，其与MVA一起共递送至容许细胞(CEF或BHK)，从而通过自发同源重组将想要的抗原与上游启动子序列和下游转录终止信号一起插入MVA基因组中1，5，21。
尽管这种方法被广泛使用，但它可能很费力，并且在抗原插入期间以及额外地在随后标志物去除期间为获得重组MVA的同质群受到多轮选择的阻碍21。传统转染/感染方法中的这些缺点对于生成多抗原MVA载体尤其成问题，其中抗原插入两个或更多个插入位点中，这会降低MVA疫苗的稳定性18，22。作为传统转染/感染方法的替代并有助于生成多抗原MVA载体，已经开发了使用细菌人工染色体(BAC)技术生成MVA重组体的方法23-25。这些方法允许重复操作，通过高效和通用的诱变技术将抗原插入MVA基因组中，并以禽痘病毒(FPV)作为辅助病毒，在BHK细胞中重构重组MVA的同质病毒群，这是“启动(jump-start)”非感染性MVA基因组的转录所需的23。
合成痘病毒的构建
本文公开了从天然衍生或化学合成的DNA产生基于痘病毒的载体或重组痘病毒载体的方法。在某些实施例中，单个DNA片段衍生自病毒DNA或为化学合成的并且包含痘病毒的整个基因组序列。该单个DNA片段可用于转染宿主细胞，从而重构痘病毒。在其他实施例中，两个或更多个天然衍生或化学合成的DNA片段或其组合用于共转染宿主细胞，其中每个DNA片段包含痘病毒基因组DNA的部分序列，在两个相邻DNA片段的末端具有重叠序列，使得当两个或更多个DNA片段共转染入宿主细胞时，它们通过同源重组彼此组装以形成包含想要的痘病毒基因组的全长序列的痘病毒。在某些实施例中，重叠序列的长度在约100bp和约5000bp之间。
在某些实施例中，缩短的基因组序列而不是整个基因组序列或在痘病毒基因组序列的非必需基因或区域中具有一个或多个缺失或一个或多个修饰的改变的基因组序列，或包含来自两种或多种不同痘病毒的基因组序列的杂合衍生物可用于产生本文公开的载体。
在某些实施例中，可进一步修饰包含痘病毒基因组或亚基因组DNA的一个或多个天然衍生或化学合成的DNA片段以形成由天然和合成痘病毒基因组DNA序列构成的人工杂合片段。在其他实施例中，天然衍生或化学合成的一个或多个DNA片段可由衍生自两种不同痘病毒的序列构成以形成痘病毒杂合序列。一个或多个DNA片段可由衍生自以下的痘病毒序列构成或不同痘病毒序列构成的序列构成：MVA(NCBI登录号#U94848，#AY603355)，痘苗病毒(#NC_006998，#LT966077)，骆驼痘病毒(#NC_003391)，牛痘病毒(#NC_003663)，鼠痘病毒(#NC_004105)，猴痘病毒(#NC_003310)，浣熊痘病毒(#NC_027213)，臭鼬痘病毒(#NC_031038)，沙鼠痘病毒(#NC_008291)，天花病毒(#NC_001611，#L22579)，维乐痘病毒(Velopox virus)(#NC_031033)，金丝雀痘病毒(#NC_005309)，猪痘病毒(#NC_003389)，FPV(#NC_002188，#MH734528)，粘液瘤病毒(#GQ409969)，绵羊痘病毒(NC_004002)，山羊痘病毒(#NC_004003)，(Orf病毒#NC_005336)，兔纤维瘤病毒(#NC_001266)，这些痘病毒的任何株变体，或任何其他痘病毒或其株变体。
在某些实施例中，宿主细胞在转染包含痘病毒基因组或亚基因组DNA的序列的一个或多个DNA片段之前，期间，或之后被辅助病毒如FPV感染。辅助病毒可以是感染宿主细胞并允许启动痘病毒转录和复制的任何合适的病毒。本文使用的示例是宿主细胞中的FPV，而不经历与痘病毒DNA的同源重组。辅助病毒无法在宿主细胞中复制。此外，辅助病毒本身不是重构的痘病毒的组成部分，例如为本申请目的的FPV。在某些实施例中，牛痘病毒，Shope纤维瘤病毒，或其他合适的痘病毒可用作辅助病毒。在某些实施例中，用于转染的一个或多个DNA片段可为线性化，环化，或线性化和环化DNA片段的组合。在某些实施例中，用于转染的一个或多个DNA片段被克隆至载体如质粒或BAC和/或维持在宿主细胞如细菌细胞，例如，大肠杆菌中。
在某些实施例中，一个或多个DNA片段进一步包含痘病毒的反向末端重复(ITR)区之一或两者。在某些实施例中，ITR的序列可包含一个或多个改变或变体，其不影响重构的痘病毒的设计方案。在一个实施例中，重构痘病毒的一个或多个DNA片段可仅包含部分ITR序列。例如，sMVA片段F1和F3以及重构的sMVA载体或重组sMVA载体(图1-4)可能仅包含部分MVAITR序列。在某些实施例中，进一步修饰一个或多个DNA片段以将痘病毒末端发夹环(HL)序列添加在一端或两端作为双链体拷贝(双链DNA)或在5’和/或3’端作为单链核苷酸序列。例如，可以将HL序列作为正义(5’→3’)或反义(3’→5’)方向的双链或单链DNA序列添加至合成DNA片段的任一端或两端。在某些实施例中，进一步修饰一个或多个DNA片段以将痘病毒多联体(concatemeric)解析(CR)序列添加在一端或两端作为双链DNA序列或在5’和/或3’端作为单链核苷酸序列。CR序列可以基于衍生自共有序列5’-T6-N7-9-T/C-A3-T/A-3’的任何序列，其中A是腺嘌呤，C是胞嘧啶，G是鸟嘌呤，T是胸腺嘧啶，N是任何核苷酸。在某些实施例中，可以将两个CR序列添加至HL序列的两端以形成CR-HL-CR序列。CR-HL-CR序列可以添加至一个或多个DNA片段的一端或两端作为双链DNA序列，或添加至5’端，3’端，或两端作为单链核苷酸序列。在其他实施例中，仅将HL或CR序列添加至一个或多个DNA片段的一端或两端作为双链或单链DNA序列。在某些实施例中，所有DNA片段的一端或两端均包含HL或CR序列或其组合。在其他实施例中，并非所有DNA片段均包含HL或CR序列。在某些实施例中，仅DNA片段的子集或亚群包含HL或CR序列，或其组合。ITR，HL，或CR序列可能衍生自MVA(NCBI登录号#U94848，#AY603355)，痘苗病毒(#NC_006998，#LT966077)，骆驼痘病毒(#NC_003391)，牛痘病毒(#NC_003663)，鼠痘病毒(#NC_004105)，猴痘病毒(#NC_003310)，浣熊痘病毒(#NC_027213)，臭鼬痘病毒(#NC_031038)，沙鼠痘病毒(#NC_008291)，天花病毒(#NC_001611，#L22579)，维乐痘病毒(Velopox virus)(#NC_031033)，金丝雀痘病毒(#NC_005309)，猪痘病毒(#NC_003389)，FPV(#NC_002188，#MH734528)，粘液瘤病毒(#GQ409969)，绵羊痘病毒(NC_004002)，山羊痘病毒(#NC_004003)，(Orf病毒#NC_005336)，兔纤维瘤病毒(#NC_001266)，这些痘病毒的任何株变体，或任何其他痘病毒或其株变体。
在某些实施例中，本文使用的HL或CR序列公开如下：
含有侧翼为MVA多联体解析序列的MVA末端发夹环(HL)的双链体拷贝的末端CR-HL-CR序列的序列(长度为215bp，5’→3’)(SEQ ID NO：1)，其中CR序列加下划线，HL序列加斜体和双下划线：
含有侧翼为多联体解析序列的MVA末端发夹环(HL)的互补形式的双链体拷贝的末端CR-HL-CR序列的序列(长度为215bp，5’->3’)(SEQ ID NO：2)，其中CR序列加下划线，HL序列加斜体和双下划线：
MVA末端发夹环的序列(HL，长度为165nt，5’→3’)(SEQ ID NO：3)：
MVA末端发夹环的互补形式的序列(HL，长度为165nt，5’->3’)(SEQ ID NO：4)：
含有侧翼为多联体解析序列的痘苗末端发夹环(HL；S型)的双链体拷贝的末端CR-HL-CR序列的序列(长度为154bp，5’->3’)(SEQ ID NO：5)，其中CR序列加下划线，HL序列加斜体和双下划线：
含有侧翼为多联体解析序列的痘苗末端发夹环(HL；F型)的双链体拷贝的末端CR-HL-CR序列的序列(长度为154bp，5’->3’)(SEQ ID NO：6)，其中CR序列加下划线，HL序列加斜体和双下划线：
痘苗病毒末端发夹环的序列1(HL，S型，长度为104nt，5’→3’)(SEQ ID NO：7)：
痘苗病毒末端发夹环的序列2(HL，F型，长度为104nt，5’→3’)(SEQ ID NO：8)：
MVA多联体解析序列的序列1(CR，长度为20bp，5’→3’)(SEQ ID NO：9，正义方向)，包括在工作示例中的发夹双链体拷贝的左端：
MVA多联体解析序列的序列2(CR，长度为20bp，5’→3’)(SEQ ID NO：10，反义方向)，包括在工作示例中的发夹双链体拷贝的右端：
如工作示例所示，本文公开的sMVA和rsMVA重组体基于三个～60kbp长的DNA片段的化学合成而生成，这些DNA片段包含由Antoine及同事公布的整个～178kbp的MVA基因组(登录号#U94848)26。这包括内部独特区(UR)和侧翼～9.6kbp长的反向末端重复(ITR)区，如图1所示。Antoine等人公布的MVA基因组序列(登录号#U94848)26，本文称为MVA株Antoine，其与1974年获得许可并可商购的国立卫生研究院克隆1(MVANIH克隆1)的MVA基因组不同仅为内部UR中的五个碱基对，其在序列上与MVA株Acambis(登录号#AY603355)所公布的基因组相同。sMVA片段1(F1)包含MVA基因组的左ITR和～50kbp的内部UR的左端；sMVA片段2(F2)包含MVA基因组～60kbp的内部UR的中间部分；和sMVA片段3(F3)包含MVA基因组～50kbp的内部UR的右端和右ITR(图1)。sMVAF1和F2以及sMVA F2和F3被设计为共享～3kbp的重叠序列以允许通过同源重组重构完整的MVA基因组(图1)。将侧翼为MVA CR序列的165个核苷酸长的MVA末端HL的双链体拷贝添加至三个片段中的每一个的两端，以促进MVA基因组的解析和包装26(图1)。另外地，SfiI和FseI限制性位点包括在三个片段中的每一个的两端，使得片段可以在有或没有HL和CR序列的情况下释放或线性化。唯一的例外是F1和F3的ITR处的HL和CR序列，它们以相同的排列融合至端部，因为它们出现在MVA多联体复制中间体的连接处26(图1)。如图1所示，侧翼为HL和CR序列以及重叠的同源重组序列的三个sMVA片段由Genscript Biotech使用基于酵母的重组系统合成和生成。所有三个sMVA片段均被克隆至称为pCCI-Brick的酵母穿梭载体，其包含细菌mini-F复制子元件，可用作BAC载体以在细菌中以低拷贝数稳定繁殖三个片段(图1)。sMVA片段最终被克隆入重组缺陷的DH10B或EPI300大肠杆菌细胞。
在某些实施例中，包括在三个MVA片段中的每一个的两端具有侧翼CR序列的HL的双链体拷贝-与仅在F1和F3的ITR的端部相反，它们在多联体复制中间体中天然存在。这种设计基于这些序列元件在痘病毒DNA复制期间所具有的内在功能。所包装的痘病毒基因组中的末端HL将基因组末端处的两条DNA链连接至连续的多核苷酸链，其中它们以不完全碱基配对和AT丰富的反向和互补形式存在于两端26-29。痘病毒HL序列对于将双链DNA基因组复制成多聚体头对尾或头对头多联体复制中间体很重要，其中HL序列作为精确的双链体拷贝存在于多联体连接处30-32。CR元件包含高度保守的痘病毒解析序列，可以在与末端HL直接相邻的大的ITR两端的包装后基因组中找到26，27，33，34。多联体复制中间体中的痘病毒CR元件存在于基因组连接处的HL双链体拷贝的任一位点，这些CR/HL/CR序列排列对于单位长度基因组的解析和随后的基因组包装至关重要33-36。当含有痘病毒多联体连接的环状质粒(由侧翼为CR元件的HL双链体拷贝构成)被转染入被痘病毒感染的细胞时，它们会自发分解成具有末端HL的线性微染色体36，37。在某些实施例中，当转染入宿主细胞时，环化的sMVA片段可以在宿主细胞中以独立于起源的方式立即复制。据报道，任何转染入被痘病毒感染的细胞的环状DNA分子都以独立于起源的方式复制，并且这种非特异性序列复制不会通过插入任何病毒DNA片段而增强38。在其他实施例中，当转染入宿主细胞时，环化的sMVA片段可以通过插入载体或MVA序列的真核或病毒复制起源进行复制。
所公开的合成痘病毒如sMVA的构建技术包括HL和CR序列，使得含有侧翼为多联体基因组连接(CR-HL-CR)和重叠基因组序列的三个合成MVA片段的环状质粒或DNA分子转染入FPV-感染的BHK或CEF细胞将促进(1)三个sMVA片段的转录和复制，(2)从质粒载体序列解析三个sMVA片段，和(3)三个sMVA片段重组为全长基因组，最终导致将具有末端HL的无载体基因组包装成预先形成的病毒颗粒(图1和2)。这些事件可能由于FPV感染而立即启动，或者它们可能在三个sMVA片段的转录启动和复制后的逐步过程中发生。在另一个实施例中，从三个sMVA片段重构sMVA的过程可能在没有FPV或其他辅助病毒的情况下启动。作为使用环状质粒或DNA分子从三个MVA片段重构sMVA的替代策略，也可能通过基于三个sMVA片段的线性化形式的方法促进sMVA的重构，例如，使用如图1和2所示的添加的FseI和SfiI限制性位点。
无论是使用三个MVA片段的环状或线性化形式，还是环状和线性化形式的组合，片段的末端均可能包含或不包含HL和CR序列。在某些实施例中，仅片段的子集可能包含HL和CR序列，或者它们可能作为单链或双链DNA序列以正义或反义方向添加至片段的仅一端或两端，例如，以它们仅存在于F1和F3的MVA部分序列的方式，其中它们天然出现在假定的多联体复制中间体中。在另一个示例中，并非所有F1片段均包含HL和CR序列；相反，有或没有HL和CR序列的F1片段可能在构建过程中混合。同样地，并非所有F2或F3片段均需要包含HL和CR序列，但F2或F3片段的子集或亚群可能包含HL和CR序列。在某些实施例中，HL和/或CR序列也可能化学连接为三个片段的线性化形式的单链或双链DNA序列。
在另一个实施例中，可能通过引入插入，缺失，或点突变，或通过插入编码一个或多个抗原，亚单位，或其片段的一个或多个异源DNA序列对由sMVA片段重构的sMVA病毒进行修饰。这些修饰或抗原序列可能使用具有介导同源重组的同源侧翼物的转移质粒通过常规转染/感染方法引入sMVA DNA片段。在某些实施例中，编码一个或多个抗原，亚单位，或其片段的一个或多个核苷酸序列可能针对真核或痘苗表达进行密码子优化。例如，抗原，亚单位，或其片段可能针对在宿主细胞中转录或表达的稳定性进行优化。可能使用多种密码子优化技术，包括但不限于通过引入不导致所编码蛋白中氨基酸变化的沉默点突变而改变连续四个相同核苷酸(例如，GGGG，CCCC，TTTT，AAAA)，或使密码子使用适应于特定宿主物种。
在另一个实施例中，由宿主细胞如BHK或CEF细胞中的sMVA片段重构的sMVA病毒可用于生成包含全长sMVA基因组的sMVA细菌人工染色体(BAC)。BAC载体序列可通过包含具有介导同源重组的侧翼同源序列的BAC序列的转移构建体插入sMVA基因组中。可能从宿主细胞如BHK或CEF细胞分离具有插入的BAC序列的环状复制中间体，并通过电穿孔或化学转化将其转移入大肠杆菌细胞，从而使大DNA构建体如DH10B或EPI300稳定繁殖。在另一个实施例中，可能将sMVABAC转移入GS1783大肠杆菌细胞并通过Red-重组技术如En passant诱变进行操作。
在另一个实施例中，sMVA片段可用于通过体外连接方法或通过其他体外DNA组装方法如Gibson或GoldenGate组装来重构完整或全长sMVA基因组。
抗原或其他异源基因序列的表达
本文公开的技术具有在转染前将多个抗原，亚单位或其片段，或其他异源DNA序列插入一个或多个天然衍生或化学合成的DNA片段中的灵活性，使得在重构后获得表达抗原，亚单位或其片段的合成痘病毒。这些抗原，亚单位或其片段可衍生自或基于病毒，如巨细胞病毒(CMV)，爱泼斯坦-巴尔病毒(EBV)，卡波氏肉瘤相关疱疹病毒(KSHV)，其他疱疹病毒，寨卡病毒，拉沙病毒，丙型肝炎病毒(HCV)，肝炎(HBV)，冠状病毒(如2019-nCoV，SARS，MERS)，流感，或任何其他病毒，细菌，或其他形式的感染性病原体。抗原序列还可衍生自或基于癌症相关联蛋白(例如，p53，视网膜母细胞瘤，新抗原)。同样地，可将其他异源基因序列插入一个或多个天然衍生或化学合成的痘病毒DNA片段中。此类异源基因序列包括但不限于荧光标志物，RNA如RNAi，shRNA，LNCRNA，miRNA等的cDNA拷贝，干扰素，细胞因子，抗体或其片段，或在原核或真核细胞中表达的其他蛋白质。在某些实施例中，抗原序列或异源基因序列可与上游天然或合成痘病毒启动子(pSyn，P11，H5，mH5，P28，ATI，pHyb，p7.5)和下游转录终止信号(TTTTTAT)插入sMVA片段中，使得当痘病毒片段转染入宿主细胞时，抗原序列或异源基因序列被表达。
抗原，亚单位，或其片段的DNA序列，或其他异源基因序列，可以插入一个或多个DNA片段内的一个或多个痘病毒插入位点中。以sMVA为示例，在转染宿主细胞之前，可以将一个抗原或其片段的DNA序列插入位于一个sMVA DNA片段(例如，sMVA F2)上的单个MVA插入位点中(图3)。在另一个示例中，在转染宿主细胞之前，可以将两个或更多个抗原或其片段的DNA序列插入位于一个DNA片段(例如，sMVAF2)上的单个MVA插入位点中。这些抗原DNA序列可在单个启动子或两个或更多个启动子的控制下。同样地，抗原DNA序列可共享相同的转录终止信号或具有不同的转录终止信号。编码两个或更多个抗原的核苷酸序列也可通过介导核糖体跳跃的小核糖核酸病毒(P2A，T2A，F2A等)的2A序列或通过内部核糖体进入位点(IRES)连接，使得抗原在翻译后被加工并自组装以形成多组分抗原复合物。
在某些实施例中，编码一个或多个抗原，亚单位或其片段的一个或多个DNA序列，或其他异源DNA序列在5’端，3’端，或一个或多个必需或非必需痘病毒开放阅读框(ORF)的任何内部位置处插入框，使得当将一个或多个天然衍生或化学合成的痘病毒DNA片段转染入宿主细胞时，表达包含痘病毒蛋白与一个或多个抗原，亚单位或其片段，或添加至C-末端，N-末端，或痘病毒蛋白的任何内部位置的其他异源蛋白序列的一个或多个融合蛋白。在一些实施例中，编码一个或多个抗原，亚单位或其片段的一个或多个DNA序列或其他异源DNA序列通过小核糖核酸病毒(P2A，T2A，F2A等)的2A编码序列与一个或多个痘病毒ORF连接，使得所表达的包含痘病毒蛋白与一个或多个抗原，亚单位或其片段，或添加至C-末端，N-末端，或痘病毒蛋白的任何内部位置的其他异源蛋白序列的一个或多个融合蛋白通过核糖体跳跃机制在2A接头序列处被加工(“切割”)成单个组分。在其他实施例中，编码一个或多个抗原，亚单位或其片段的一个或多个DNA序列，或其他异源DNA序列通过内部核糖体进入位点序列与一个或多个必需或非必需痘病毒ORF连接，使得当将一个或多个天然衍生或化学合成的痘病毒DNA片段转染入宿主细胞时，通过嵌合多顺反子表达构建体同时表达一种或多种痘病毒蛋白和一个或多个抗原，亚单位或其片段，或其他异源蛋白序列，表达构建体内每个ORF的5’端处具有多个翻译起始位点。
在某些实施例中，可将两个或更多个抗原，亚单位或其片段的DNA序列或其他异源基因序列插入两个或更多个MVA插入位点中，其可能位于相同的sMVA片段上或不同的sMVA片段上。例如，两个或多个抗原，亚单位或其片段的DNA序列可以插入两个不同的MVA插入位点中，均位于sMVA F1上。在另一个示例中，两个或多个抗原，亚单位或其片段的DNA序列可插入两个不同的MVA插入位点中，一个位于sMVA F1上，另一个位于sMVA F2上(图4)。应当理解，不同的DNA片段可能插入有相同抗原，亚单位或其片段的DNA序列。替代地，不同的sMVA片段可能插入有不同抗原，亚单位或其片段的DNA序列，使得在转染后重构时，由合成的MVA表达的不同抗原，亚单位或其片段自加工并自组装成病毒颗粒，病毒复合物，或包含亚单位或其片段的完整抗原。
如工作示例所示，先前建立的使用BAC技术16，18，24，25生成重组MVA载体的方法适于使用三个sMVA片段生成rsMVA重组体。由于三个sMVA片段已被克隆至具有mini-F复制子的BAC载体，它们可以在细菌中稳定繁殖，因此可以通过高效重组方法(如EnPassant诱变或其他基于大肠杆菌的操作过程)对其进行操作39，40。使用这些方法，可以将天然衍生或合成的异源抗原序列连同上游痘苗病毒启动子和下游转录终止信号以平行，连续，或重复的方式插入sMVA片段中的仅一个，两个，或全部三个中的几乎每个MVA基因组位置(图3和4)。这些插入位点可能包括常用插入位点，如MVA缺失2(Del2)位点，开放阅读框(ORF)44L和45L之间的基因间区域(IGR)(IGR44/45)，ORF69R和70L之间的IGR(IGR69/70)，64L和65L之间的IGR(IGR64/65)，胸苷激酶(TK)基因插入位点，或MVA缺失3(Del3)位点(图1)，或任何其他MVA缺失位点，基因间区域，或基因插入位点(ORF编号基于MVA株Antoine(登录号#U94848))。这些方法还可用于在一个或多个sMVA片段的一个或多个位置生成一个或多个点突变，插入，或缺失。然后可以从大肠杆菌中分离被修饰的sMVA片段，并通过多个转染方法将其作为环状或线性化DNA分子共转移入被辅助病毒感染的BHK或CEF细胞，以启动具有单抗原，双抗原，或多抗原插入或基因组改变的rsMVA的重构(图3和4)。在某些实施例中，可以在不添加辅助病毒的情况下启动rsMVA重构。在某些实施例中，三个sMVA片段还可用于通过体外连接方法生成具有单抗原或多抗原插入或基因组改变的sMVA。在某些实施例中，可以将一个或多个抗原，亚单位或其片段插入sMVA片段的一个或多个MVA插入位点中。在某些实施例中，仅一个sMVA片段插入有一个或多个抗原或其片段(图3)。在某些实施例中，两个或更多个sMVA片段插入有一个或多个抗原或其片段(图4)。在某些实施例中，所有sMVA片段均插入有一个或多个抗原，亚单位或其片段(图4)。当两个或更多个sMVA片段插入有抗原，亚单位或其片段时，对于不同的sMVA片段，抗原，亚单位或其片段可能相同或不同。例如，sMVA F1可插入有一种类型的抗原或其片段，sMVAF2可插入有不同类型的抗原或其片段。替代地，sMVA F1和F2可插入有相同类型的抗原或其片段，sMVAF3可插入有相同类型的抗原或其片段或不同类型的抗原，亚单位或其片段。
通过本文公开的技术产生的痘病毒载体可用于，例如，生成多抗原疫苗载体，以刺激针对多种病症如病毒感染和癌症的多功能体液和细胞免疫反应。例如，基于三个sMVA片段F1-F3的所公开的技术可用于生成多抗原rsMVA疫苗载体，以刺激针对人巨细胞病毒(HCMV)的多功能体液和细胞免疫反应。这可包括基于HCMV五聚体复合物(PC)的五个亚单位，糖蛋白B(gB)，磷蛋白65(pp65)，和即早1和2蛋白(IE1和IE2)的免疫显性抗原序列。抗原序列可被分开地或组合地作为2A连接的多顺反子表达构建体插入不同的常用MVA插入位点(Del2，Del3，IGR44/45，IGR69/70，IGR64/65)处的sMVA片段中，以生成表达5，6，7，8，或9个HCMV抗原的rsMVA疫苗载体，如图6和图10所示。也可生成仅表达单一HCMV抗原或上述九个HCMV抗原的任何其他数量或组合的rsMVA载体。所有抗原序列或表达构建体都可连同上游mH5启动子和下游转录终止信号插入。这些载体可用于在动物模型或人中刺激针对HCMV的免疫反应。
表达系统和疫苗
根据本文描述的实施例，本文提供了MVA表达系统。在某些实施例中，表达系统可表达一个或多个想要的抗原，亚单位或其片段或其他异源蛋白序列。
如上所述，一个或多个sMVA片段可插入有编码一个或多个抗原，亚单位或其片段的DNA序列，使得重构的sMVA同时表达所述抗原，亚单位及其片段。
在某些实施例中，插入sMVA片段中的抗原DNA序列可基于天然DNA序列或来自化学合成。在其他实施例中，抗原DNA序列可针对在表达系统内的表达和稳定性进行优化。
基于sMVA所表达的抗原，本文描述的sMVA可为可用于治疗或预防病毒感染或治疗癌症的方法的疫苗组合物的一部分。如本文所述的疫苗组合物可包含治疗有效量的如本文所述的sMVA，并且根据标准方法进一步包含药学上可接受的载体。可接受的载体的示例包括生理上可接受的溶液，如无菌盐水和无菌缓冲盐水。
在一些实施例中，疫苗或药物组合物可与药学有效量的佐剂组合使用以增强预防或治疗效果。任何可刺激免疫系统并增加针对疫苗的反应但本身不具有任何特异性抗原作用的免疫佐剂均可用作佐剂。许多免疫佐剂模拟进化上保守的分子，称为病原体相关联分子模式(PAMP)，并被一组称为Toll样受体(TLR)的免疫受体识别。可根据本文描述的实施例使用的佐剂的示例包括弗氏完全佐剂，弗氏不完全佐剂，双链RNA(TLR3配体)，LPS，LPS类似物，如单磷酰脂质A(MPL)(TLR4配体)，鞭毛蛋白(TLR5配体)，脂蛋白，脂肽，单链RNA，单链DNA，咪唑喹啉类似物(TLR7和TLR8配体)，CpG DNA(TLR9配体)，Ribi佐剂(单磷酰脂A/海藻糖二甲藻酸盐)，糖脂(α-GalCer类似物)，未甲基化CpG岛，油乳剂，脂质体，病毒体，皂苷(皂苷的活性部分如QS21)，胞壁酰二肽，明矾，氢氧化铝，角鲨烯，BCG，细胞因子如GM-CSF和IL-12，趋化因子如MIP 1-α和RANTES，激活的细胞表面配体如CD40L，N-乙酰胞壁胺-L-丙氨酰-D-异谷氨酰胺(MDP)，和胸腺素α1。可以根据症状的程度合适地选择所使用的佐剂的量，所述症状如有皮肤软化，疼痛，红斑，发热，头痛，和肌肉疼痛，可作为施用这种类型的疫苗后的人或动物免疫反应的一部分被表达。
在进一步的实施例中，如上文所讨论，与本发明的疫苗一起使用多种其他佐剂，药物或添加剂可增强通过施用疫苗或药物组合物实现的治疗效果。药学上可接受的载体可含有痕量的添加剂，如增强等渗性和化学稳定性的物质。此类添加剂在所使用的剂量和浓度下应对人或其他哺乳动物受试者无毒，其示例包括缓冲剂，如磷酸，柠檬酸，琥珀酸，乙酸，和其他有机酸，及其盐；抗氧化剂，如抗坏血酸；低分子量(例如，少于约10个残基)多肽(例如，聚精氨酸和三肽)蛋白质(例如，血清白蛋白，明胶，和免疫球蛋白)；氨基酸(例如，甘氨酸，谷氨酸，天冬氨酸，和精氨酸)；单糖，二糖，和其他碳水化合物(例如，纤维素及其衍生物，葡萄糖，甘露糖，和糊精)，螯合剂(例如，EDTA)；糖醇(例如，甘露醇和山梨糖醇)；抗衡离子(例如，钠)；非离子表面活性剂(例如，聚山梨醇酯和泊洛沙姆)；抗生素；和PEG。
含有本文描述的sMVA的疫苗或药物组合物可作为水溶液或冻干产品储存于单位剂量或多剂量容器，如密封安瓿或小瓶。
预防或治疗病毒感染或癌症
由一个或多个天然衍生或化学合成的DNA片段重构的痘病毒，具有或不具有插入的抗原，亚单位或其片段，或其他异源序列，可用作预防或治疗多种病毒感染或癌症的疫苗组合物。本领域普通技术人员将知道如何为待预防或治疗的病症或疾病选择特定的病毒或癌症抗原。这可包括但不限于能够引发免疫反应的任何感染性疾病或癌症抗原，如病毒包膜糖蛋白或糖蛋白复合物，免疫显性T细胞抗原，或突变的癌症新抗原。这些抗原序列或其部分可衍生自或基于病毒，如CMV，EBV，KSHV，其他疱疹病毒，寨卡病毒，拉沙病毒，HCV，HBV，冠状病毒，流感，或任何其他病毒，细菌，或其他形式的感染性病原。
以下示例旨在说明本发明的多个实施例。因此，所讨论的具体实施例不应被视为对本发明范围的限制。对本领域技术人员将显而易见的是，在不脱离本发明范围的情况下可以进行多种等效，改变，和修改，并且应当理解，这些等效实施例将被包括在本文。此外，在本公开中引用的所有参考文献均通过引用整体并入本文，如同在本文完全阐述。
示例
示例1：使用环状形式的合成MVA片段的sMVA重构
作为验证sMVA平台的初始测试，使用图2所示的过程评估从环状形式的三个sMVA片段的sMVA重构。三个sMVA片段(F1到F3)通过碱裂解41从EPI300或DH10B大肠杆菌中分离出来，使得克隆为BAC的大DNA片段稳定繁殖，并作为环状质粒通过脂转染被共转染(～1-2μg/片段)入BHK细胞单层(6孔板格式)(图5)。在感染后4小时(hpi)，以0.1感染复数(MOI)的辅助FPV感染BHK细胞以启动MVA转录和DNA复制。仅用一个MVA片段或仅两个MVA片段的组合转染的FPV感染的BHK细胞，用所有三个MVA片段转染的假感染(未被感染)的BHK细胞，和被FPV感染的假转染的BHK细胞用作对照。转染/感染的BHK细胞在合适的条件下生长，每2天使用图5所示的过程以～1∶2至1∶3的比例分散(传代)成更大的组织培养形式。在转染/感染后(dpt/i)3-6天，在用所有三个合成MVA片段转染的FPV感染的BHK细胞单层中检测到细胞病变效应(CPE)和病毒斑块形成和进展的迹象，证明了sMVA的重构。在用所有三个MVA片段转染的FPV感染的BHK细胞分散后7至8dpt/i，得到的BHK细胞单层显示90-100％的感染。相反，在任何对照中均未观察到CPE或特征性MVA病毒斑块形成的迹象。用具有100％CPE的BHK细胞单层通过常规冷冻/解冻方法制备sMVA，在BHK细胞上滴定，并用于以低MOI感染BHK细胞单层，以通过痘苗病毒糖蛋白B5R16，42免疫染色在16-72hpi评估MVA感染和扩散。
该分析表明了与MVA NIH克隆1相比，重组的sMVA具有相似的能力以形成特征性MVA病毒病灶并在BHK细胞单层中扩散(图6)，证明从三个sMVA片段形成sMVA。在感染后(dpi)1天，在sMVA和MVA NIH感染的BHK细胞单层中检测到特征性病毒病灶，而在2dpi，MVA病毒感染在感染sMVA或MVA NIH的整个BHK细胞单层中可见，并且在3dpi，被sMVA或MVANIH感染的BHK细胞单层的大多数细胞分离(detached)。相反，在假感染的对照中未检测到特征性MVA病毒感染或CPE。其他研究组最终显示了用作辅助病毒的FPV在被引入BHK或CEF细胞上的转染/感染温育时，不提供遗传物质或与MVA基因组重组43，44。
为了表征重构的sMVA的基因组，使用对三个合成MVA片段内不同基因组位置特异的引物通过PCR对从sMVA感染的BHK细胞制备的病毒DNA进行评估。从假感染(未被感染)的BHK细胞以及被NIH MVA克隆1感染的BHK细胞制备的DNA用作对照。该PCR分析揭示了衍生自重构的sMVA的基因组DNA内所有三个sMVA片段的DNA的存在(图7)。衍生自sMVA感染的BHK细胞的所有PCR产物与衍生自MVA NIH感染的BHK细胞的PCR产物相似(分子量)。这包括(1)衍生自位于sMVA F1和F3内的ITR序列的PCR产物(图7A)；(2)对应于sMVA F1衍生的的DNA的PCR产物，如左ITR过渡至内部UR左端(图7B)，和Del2插入位点(图7C)；(3)对应于sMVA F2衍生的DNA的PCR产物，如G1L/I8R插入位点(IGR69/70)(图7D)；和对应于sMVA F3衍生的DNA的PCR产物，如Del3插入位点(图7E)，内部UR右端过渡至右ITR(图7F)。此外，使用具有位于sMVAF1/F2或sMVA F2/F3重叠同源序列侧翼的结合位点的引物进行PCR分析(图1)，显示了MVA和MVA NIH感染的BHK细胞的产物大小相似(图7G-7H)，表明三个sMVA片段的的成功重组和sMVA中载体序列的去除。
对衍生自sMVA感染的BHK细胞的所有PCR产物的Sanger测序分析揭示了这些基因组位置处的序列与MVA株Antoine26所公布的序列相同，包括F1/F2和F2/F3的重组位点。唯一的例外是衍生自sMVA的Del2位点的PCR产物，其显示位于开放阅读框(ORF)021L26下游三个碱基对处的IGR的单个T到A的核苷酸改变。BLAST分析显示了sMVA DNA内的这种序列改变不存在于任何已公布的MVA或痘苗病毒基因组序列中。从大肠杆菌纯化的sMVAF1的Sanger序列分析表明了在BHK细胞中的sMVA重构之前，Del2位点处的这种特定核苷酸改变已经存在，这表明其来源于F1的化学合成或者是sMVAF1在大肠杆菌中的克隆或繁殖。来自sMVA感染的BHK细胞的PCR产物的额外的测序分析(图7I-7L)表明sMVA基因组序列在内部UR中包含所有五个Antoine特异性核苷酸多态性，这将其与MVA NIH克隆1的基因组序列区分开来。
以下DNA序列作为DNA分子正义链的核苷酸序列(5’至3’)给出。sMVA片段1的序列(F1，长度为60021bp)(SEQ ID NO：11)：
sMVA片段F1，F2，和F3的任何序列均可包含一个或多个改变或变体。例如，sMVA片段F1的序列(以登录号MW023923存放于NCBI，www.ncbi.nlm.nih.gov/nuccore/MW023923.1/)在开放阅读框021下游的非编码决定区包含1个核苷酸改变(SEQ ID NO：12)：
sMVA片段2的序列(F2，长度为63035bp)(以登录号MW023924存放于NCBI，www.ncbi.nlm.nih.gov/nuccore/MW023924.1/)(SEQ ID NO：13)：
sMVA片段3的序列(F3，长度为62068bp)(SEQ ID NO：14)：
替代地，sMVA F3的序列可在靠近ITR序列末端的88bp处的非编码决定区中包含1个核苷酸改变(以登录号MW030459存放于NCBI，www.ncbi.nlm.nih.gov/nuccore/MW030459.1/)(SEQ ID NO：15)：
还公开了用于重构完整的痘苗病毒基因组的合成痘苗病毒(sVAC)片段的示例。sVAC片段1的示例序列(F1，长度为66679bp)(SEQ ID NO：16)：
sVAC片段2的示例序列(F2，长度为66679bp)(SEQ ID NO：17)：
sVAC片段3的示例序列(F3，长度为66679bp)(SEQ ID NO：18)：
为了评估sMVA重构后细菌载体序列的去除，使用对细菌载体的sopA和cat氯霉素抗性基因特异的引物通过PCR评估了BHK细胞中sMVA连续病毒传代后sMVA感染的BHK细胞的DNA。该PCR分析显示了在7或8dpt/i可以在sMVADNA中检测到残留载体序列，尽管在sMVA的两次额外的病毒传代后在sMVA DNA中检测不到它们。总之，这些结果提供了证据，将三个合成MVA片段作为环状质粒分子共转染入FPV感染的BHK细胞，导致形成具有全长，无载体基因组的sMVA，该基因组显示具有与所公布的MVA株Antoine的基因组序列相似的序列组成26。
示例2：生成表达单一异源基因序列的重组sMVA
为了评估使用三个sMVA片段生成rsMVA，将三个片段转移入GS1783大肠杆菌细胞40，用于通过EnPassant诱变操作大BAC克隆的DNA分子39，40。这种高效的方法允许通过基于Red重组的两步诱变过程将点突变或大或小序列插入或缺失引入BAC克隆的DNA分子，而不会留下任何细菌标志物序列39，40。作为sMVA平台生成表达异源基因序列的rsMVA的初始测试，评估了表达单一荧光标志物的rsMVA的生成。如前所述将抗原序列插入MVABAC-TK18，24，Enpassant诱变用于将包含红色荧光蛋白(RFP)标志物的表达盒与上游mH5启动子和下游TTTTTAT痘苗病毒转录终止信号插入sMVA片段F2内的IGR69/70(也称为G1L/I8R)插入位点中(图3)，产生F2-RFP。通过限制性片段长度多态性(RFLP)分析以及基因插入位点的PCR和Sanger测序分析确定了被操作的sMVA片段的序列完整性。从大肠杆菌中分离出具有插入的RFP标志物的被修饰的sMVA片段F2以及未被修饰的sMVA片段F1和F3并将其共转染入BHK细胞，以使用如图5所示的过程评估在FPV作为辅助病毒存在下rsMVA的重构。如图8所示，免疫荧光成像揭示了在用F1/F2-RFP/F3质粒组合转染的BHK细胞单层中，在3-6dpt/i的红色荧光病毒斑块的形成和进展，而在7dpt/iRFP表达在整个BHK细胞单层中可见。相反，在假转染/感染的BHK细胞单层中RFP表达不可见。总之，这些结果显示了sMVA平台可用于快速生成表达单一异源基因序列的rsMVA。
示例3：生成表达两个异源基因序列的重组sMVA
为了评估用于生成具有插入不同基因组位置中的多个异源基因序列的rsMVA的sMVA平台，评估了表达两个荧光标志物的rsMVA的构建。使用GS1783细胞的En passant诱变，将包含P11启动子，RFP标志物或蓝色荧光蛋白(BFP)标志物，和TTTTTAT转录终止信号的基因表达盒分别插入sMVA F2的IGR69/70和sMVA F3的Del3位点中。从GS1783大肠杆菌细胞中分离出插入有RFP标志物(F2-RFP)的被修饰的sMVA F2和插入有BFP标志物(F3-BFP)的被修饰的sMVA F3并连同未被修饰的sMVA F1共转染入BHK细胞，以使用图5所示的过程评估在辅助病毒存在下具有RFP和BFP标志物的rsMVA的重构。如图9所示，免疫荧光成像显示了在用F1/F2-RFP/F3-BFP质粒组合共转染的BHK细胞单层中，在3-6dpt/i的双荧光(红色和蓝色)病毒斑块的形成，在7dpt/i，大多数或所有BHK细胞显示了RFP和BFP双荧光蛋白表达。这些结果提供了sMVA平台可用于快速生成表达插入不同插入位点中的两个异源基因序列的rsMVA的证据。
示例4：生成表达三个异源基因序列的重组sMVA
为了进一步评估用于生成具有多个插入的异源基因序列的rsMVA的sMVA平台，研究了表达三个荧光标志物的rsMVA的生成。在大肠杆菌中使用En passant诱变，将绿色荧光蛋白(GFP)标志物连同上游P11启动子和下游转录终止信号插入MVA F1的IGR44/45中。然后以不同的组合测试了插入有GFP标志物的所得被修饰的sMVA片段F1(F1-GFP)与荧光标记形式的F2和F3(F2-RFP和F3-BFP)以及F1，F2，和F3的未被修饰的sMVA片段，以使用图5所示的过程评估单荧光，双荧光，或三荧光sMVA表达载体。用于共转染的片段组合包括F1-GFP/F2-RFP/F3-BFP，F1-GFP/F2-RFP/F3，F1-GFP/F2/F3-BFP，F1/F2-RFP/F3-BFP，F1-GFP/F2/F3，F1/F2-RFP/F3，和F1/F2/F3-BFP。将三个未被修饰的sMVA片段(Fl/F2/F3)共转染入FPV感染的BHK细胞作为阴性对照进行评估。除阴性对照外，在用任何不同片段组合转染的BHK细胞单层中通过免疫荧光成像在3-6dpt/i观察到荧光基因表达。在7到8dpt/i，在BHK单层的大多数细胞中观察到荧光标志物表达，表明荧光重组sMVA表达载体的重构。通过冷冻/解冻技术制备了重组sMVA表达载体，在BHK细胞上滴定，并用于以低MOI感染BHK细胞单层。在16-24hpi，通过IF成像评估了被感染的BHK细胞单层，以证明表达不同荧光标志物序列的sMVA的形成和重组。该分析揭示了病毒病灶的形成，在被F1-GFP/F2-RFP/F3-BFP衍生的sMVA感染的BHK细胞单层中显示了三荧光表达；在被F1-GFP/F2-RFP/F3，F1-GFP/F2/F3-BFP，或F1/F2-RFP/F3-BFP衍生的sMVA感染的BHK细胞单层中显示了双荧光表达；和在被F1-GFP/F2/F3，F1/F2-RFP/F3，或F1/F2/F3-BFP衍生的sMVA感染的BHK细胞单层中显示了单荧光表达。总之，这些结果表明可以在大肠杆菌中操作三个sMVA片段并将其用作环状DNA分子以重构单，双，或三重组sMVA表达载体，突出了三个sMVA片段生成重组疫苗载体的潜力。
示例5：感染性疾病抗原修饰的MVA示例的构建和评估
为了显示sMVA平台生成感染性疾病多抗原疫苗载体的效用，对表达由gH，gL，UL128，UL130，和UL131A构成的五元HCMV包膜五聚体复合物(PC)的rsMVA的构建进行了评估。使用En Passant诱变在大肠杆菌中将包含2A连接的gH/gL和UL128/UL130/UL131A亚单位的抗原表达盒分别插入位于sMVA F2的IGR69/70和位于sMVA F3的Del3位点中。将F2和F3的被修饰的sMVA片段连同F1的未被修饰的sMVA片段转染入FPV感染的BHK细胞，以重构表达所有五个PC亚单位的sMVA(rsMVA-PC)。作为对照，生成仅表达gH/gL或UL128/130/131A亚单位的rsMVA以及没有任何插入的抗原序列的sMVA。通过Western Blot证明抗原序列的表达，并且使用靶向由PC的两个或更多个亚单位形成的构象表位的中和抗体(NAb)通过流式细胞术(FC)验证由rsMVA-PC表达的PC亚单位形成的多蛋白复合物。为了研究rsMVA-PC载体刺激NAb的免疫原性，Balb/c小鼠以4周间隔通过腹膜内途径用rsMVA-PC或对照载体免疫三次。在免疫后的多个时间点，在MRC-5成纤维细胞(FB)和ARPE-19上皮细胞(EC)上测量HCMV特异性NAb反应。该分析可以揭示在用rsMVA-PC免疫的小鼠中对FB和EC特异性NAb反应的有效刺激，而在用对照载体免疫的小鼠中没有或仅测量到最小反应。这些结果可显示sMVA疫苗平台可用于生成表达所有五个PC亚单位的多抗原MVA疫苗载体，这些PC亚单位彼此组装形成NAb表位并刺激小鼠中的有效NAb反应。
示例6：sMVA表达的2019-nCoV的构建和评估
举例说明了sMVA平台针对冠状病毒株2019-nCoV(武汉)生成疫苗的效用，该株最近作为一种新的高度传染性和致病性冠状病毒出现。由于冠状病毒的S(刺突)蛋白参与受体识别以及病毒附着和进入，并且是保护性体液和细胞免疫的主要靶标，因此它代表了开发冠状病毒(CoV)疫苗和治疗剂的潜在目标。编码全长S蛋白(～1273个氨基酸)，2019-nCoV株的S蛋白的免疫原性S1结构域，或S1结构域的受体结合结构域(RBD)的cDNA分别插入sMVA片段F3的MVADel3位点中。然后将所得的被修饰的sMVAF3片段与未被修饰版本的sMVA片段F1和F2共转染入BHK细胞，以使用如图5所示的过程启动表达新冠状病毒S蛋白(sMVA-2019-nCoV-S)，S1结构域(sMVA-2019-nCoV-S1)，或RBD结构域(sMVA-2019-nCoV-RBD)的sMVA的重构。通过免疫印迹和流式细胞术分析证明来自sMVA重组体的S蛋白，S1结构域，或RBD结构域的表达。来自被感染的人，小鼠，或兔的恢复期血清用作免疫印迹的检测试剂。在某些情况下，标签如HA共价连接在羧基末端，针对它们的抗体用作免疫印迹或流式细胞术的检测试剂。类似地，将额外的免疫原性蛋白，例如，2019-nCoV的N或M抗原插入sMVA的独特基因插入区域中，以开发多抗原疫苗。例如，将这些2019-nCoV抗原中的一个或多个插入一个或多个插入位点中，如sMVA片段F3的Del3位点和sMVA片段F2的IGR69/70。
为了测试sMVA构建体的免疫原性和保护性功效，可以使用两种动物模型：(1)鉴于在老年人中观察到的更严重的症状，12个月大的Balb/c小鼠以4周间隔通过皮下和肌肉内途径用1x107-1x108的sMVA斑块形成单位(Pfu)免疫两次；(2)考虑到人血管紧张素转换酶2(hACE-2)在nCoV进入肺细胞的潜在参与，使用表达人hACE2受体的转基因小鼠以测试疫苗功效。
为了测试sMVA构建体的免疫原性和保护性功效，血管紧张素转换酶2(ACE-2)的转基因Balb/c小鼠以4周间隔通过皮下和肌肉内途径用1x107-1x108的sMVA斑块形成单位(Pfu)免疫两次。如前所述，在每次免疫后1周测量针对2019-nCoV-S蛋白和衍生物特异的中和抗体反应和T细胞反应。在加强免疫后45天，小鼠被与疫苗抗原同源的7x10450％组织培养感染剂量(TICD50)的2019-nCoV和异源株(SARS-CoV和MERS-CoV)感染，并在攻击后4天处死动物，收集其肺用于测量病毒载量和进行组织病理学分析。在假免疫和非重组MVA免疫的对照组以及受到异源CoV株攻击的动物中均发现平均＞11,000至＞20,000 2019-nCoV基因组当量/ng总RNA的大病毒载量。与此形成鲜明对比的是，蛋白质(sMVA-nCoV-S)或S1结构域(sMVA-nCoV-S1)受试者肺组织的2019-nCoVRNA(病毒载量)水平显著降低，表明疫苗诱导的免疫反应有效抑制了2019-nCoV复制。所有安慰剂对照动物(MVA-GFP)在感染后4至8天死亡，而MVA-S，MVA-N，和MVA-N/S均未显示或显示最小的疾病迹象，包括最小的体重减轻。MVA-N/S免疫的小鼠受到完全保护。
组织病理学侧重于在2019-nCoV亚单位抗原免疫的动物中显著减少的肺损伤。还评估了抗体增强疾病的潜力，并发现在这些亚单位疫苗模型中不存在。NAb对S蛋白抗原及其S1和RBD衍生物的反应使用nCoV的拟型(pseudotyping)策略进行评估，该拟型策略对于抗原特异性NAb的识别是稳健的，但避免使用CoV的致病株。来自用S蛋白和衍生物免疫的动物的血清产生针对同源2019-nCoV株而不是异源CoV株(如MERS和SARS的病原体)的高滴度和中和抗体。计算每个小鼠血清样品的IC90中和滴度。基于转基因ACE2 Balb/c小鼠株疫苗研究的成功，研究了逐渐扩大的动物物种，即对2019-nCoV攻击敏感且已知对基于MVA的疫苗有反应的兔子，雪貂，和恒河猴。
示例7：癌症抗原修饰的sMVA示例的构建和评估
本示例显示了先前已用于从ATCC或NIAID获得的MVA骨架的研究的小鼠p53基因的插入46。使用enpassant将小鼠p53 cDNA插入缺失(DEL3)基因座中，使得在基因座的确切插入位点不进行额外的核苷酸添加或减少。通过序列分析验证插入是否准确，所有相关区域均为完整且100％序列可验证。修饰质粒F3后，将所有三个质粒组合成单个等分试样，并使用与示例2所述相同的方法，生成被修饰版本的sMVA，并在用FPV转染/感染后两天获得活病毒。活病毒在BHK细胞上浓缩和扩展，制备储备溶液(stocks)，并使用Sanger方法进行序列验证，以确定病毒在DEL3基因座中具有正确的p53基因插入序列。此外，制备病毒储备溶液并将其冷冻且长期储存，同时使用已公布的方法制备工作储备溶液，以将被修饰的sMVA储备溶液扩展到≥1x109pfu/mL的滴度。扩展后储备溶液的验证结合使用qPCR，Sanger测序，感染滴度，和Western印迹分析进行。执行所有这四个过程并获得合适的结果以确认核苷酸序列具有合适的大小，感染滴度在≥1x109pfu/mL的范围内，并且Western印迹分析证实了大约53Kd的蛋白带。本领域技术人员可以使用人版本的p53基因作为疫苗来应用这种方法以保护人免受癌症进展。
鼠(mu)p53-sMVA
雌性6-8周龄BALB/C小鼠获自杰克逊实验室(巴尔港，ME)并维持在特定的无病原体环境中。所有研究均经希望之城国家医学中心研究动物护理委员会批准，并根据美国实验动物护理认证协会指南进行。Meth A肉瘤细胞(Meth A)是纪念Sloan-Kettering癌症中心(纽约，NY)的LJ Old博士的礼物。MethA作为腹水瘤传代。抗-CTLA-4(9H10)是MD安德森癌症中心(休斯顿，TX)的James Allison博士的礼物。使用CELLine装置(BD生物科学，山景城，CA)产生抗体。通过蛋白G-琼脂糖(Amersham生物科学，乌普萨拉，瑞典)吸附纯化IgG抗体，然后用0.1M甘氨酸-HCL(pH2.7)洗脱。产物用磷酸盐缓冲生理盐水透析，并使用SentryPlus离心过滤装置(密理博，贝德福德，MA)浓缩。对照叙利亚仓鼠IgG获自杰克逊免疫研究(西格罗夫，PA)。rsMVA滴度通过使用VECTASTAIN Elite ABC试剂盒(Vector实验室，伯林盖姆，CA)对被感染的培养物进行免疫染色而确定。sMVA表达的小鼠p53蛋白的抗原特异性检测使用抗p53抗体，pab122，然后与试剂盒中提供的过氧化物酶标记的山羊抗小鼠二抗温育。还使用与构建鼠sMVAp53相同的技术构建表达CMV-pp65的对照sMVA。
体内肿瘤攻击实验
6周龄雌性BALB/C小鼠通过皮下途径在左侧注射5x105METH A细胞。在第三天，通过腹膜内注射5x107pfu的sMVAp53治疗小鼠。阴性对照小鼠被注射5x107pfu的sMVApp65或磷酸盐缓冲盐水。额外的阳性对照使用原始报告中描述的相同鼠MVAp53。每周使用荧光素酶技术通过IVIS成像方法评估皮下肿瘤，如果没有将荧光素酶基因插入METHA肉瘤细胞，则使用卡尺评估皮下肿瘤。额外的方法是在左侧注射与sMVA感染年龄相同的BALB/C小鼠1X106METHA细胞。尽管CTLA-4(9H10)抗体治疗，但该肿瘤显示在大多数小鼠中产生快速致死肿瘤。在肿瘤接种后第七天，小鼠腹膜内注射5x107pfu的sMVAp53。对照与上述相同。在肿瘤注射后第六天，第九天，和第十二天，分别以100，50，和50微克的剂量腹膜内注射抗-CTLA-4(9H10)抗体或对照仓鼠抗体。
示例8：sMVA的构建与体外和体内表征
如图1所示设计的三个sMVA片段，当作为环状DNA质粒共转染入辅助病毒感染的细胞时，可以分解成线性微染色体，经由共享的同源序列彼此重组，最终包装成全长MVA基因组。所有三个sMVA片段都被克隆至大肠杆菌作为细菌人工染色体(BAC)克隆。
使用先前采用的过程从BAC拯救MVA16，24，25，在将三个DNA质粒共转染入BHK细胞后用禽痘(FPV)作为辅助病毒重构sMVA病毒(图2)-这对FPV是不容许的。两种不同的FPV株(HP1.441和TROVAC)用于促进sMVA病毒重构(图12A)。超纯化的sMVA病毒在病毒在CEF中繁殖后产生，这常用于MVA疫苗的产生。用重构的sMVA病毒获得的病毒滴度与用野生型MVA(wtMVA)获得的病毒滴度相似(下表1)。
为了表征sMVA的病毒DNA，通过PCR比较了来自sMVA和wtMVA感染的CEF的DNA提取物的几个MVA基因组位置。对于所有被评估的基因组位置(图11A)，包括F1/F2和F2/F3重组位点，sMVA和wtMVA获得了相似的PCR结果，表明三个sMVA片段的有效重组。额外的PCR分析表明了sMVA病毒DNA中不存在任何BAC载体序列(图11A)，表明sMVA病毒重构后细菌载体元件自发且有效地去除。通过限制性酶消化对来自超纯化的sMVA和wtMVA病毒的病毒DNA进行比较，揭示了sMVA和wtMVA之间相似的基因组模式(图11B)。sMVA病毒DNA的测序分析证实了几个位置处的MVA基因组序列，包括F1/F2和F2/F3重组位点。此外，用FPV TROVAC重构的一个sMVA病毒分离株的全基因组测序证实了参考MVA基因组序列的组装，并且源自重构的sMVA病毒的病毒DNA中不存在载体特异性序列。
为了表征sMVA的复制特性，比较了sMVA和wtMVA在BHK细胞和CEF细胞上的生长动力学，这两种细胞类型已知支持生产性MVA复制4。该分析揭示了sMVA和wtMVA在BHK细胞和CEF细胞上的生长动力学相似(图12B)。另外地，在感染sMVA或wtMVA的BHK和CEF细胞单层中确定了相似的病毒病灶区域(图12C)，表明sMVA和wtMVA在MVA容许细胞中扩散的能力相似。与sMVA和wtMVA在BHK和CEF细胞中的生产性复制相比4，在感染多种人细胞系后，观察到sMVA或wtMVA仅产生有限的病毒(图12D)。这些结果与MVA严格限制的复制特性一致，并显示sMVA病毒可以在BHK和CEF细胞中有效繁殖，而不能在人细胞中有效繁殖。
为了在体内表征sMVA，在高剂量或低剂量进行两次免疫后，在C57BL/6小鼠中比较了sMVA和wtMVA的免疫原性。在第一次和第二次免疫后由sMVA和wtMVA刺激的MVA特异性结合抗体是相当的(图13A，14A)。虽然高剂量疫苗组的抗体水平在第一次免疫后超过了低剂量疫苗组，但在第二次免疫后观察到高剂量和低剂量疫苗组的抗体水平相似。另外地，在第二次免疫后，sMVA和wtMVA诱导的MVA特异性NAb反应水平未检测到显著差异(图13B，14B)。通过使用免疫显性肽的离体抗原刺激在加强免疫后测定的MVA特异性T细胞反应揭示了在接受sMVA或wtMVA的小鼠中相似的MVA特异性T细胞水平(图13C-13D和14C-14D)。这些结果表明，sMVA病毒在诱导小鼠MVA特异性体液和细胞免疫方面具有与wtMVA相似的能力。
参考文献
下面列出的参考文献，专利和公开的专利申请，以及上面说明书中引用的所有参考文献均通过引用整体并入本文，如同在本文完全阐述。
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11 Greenberg，R.N.et al.A Multicenter，Open-Label，Controlled Phase IIStudy to Evaluate Safety and Immunogenicity of MVA Smallpox Vaccine(IMVAMUNE)in 18-40 Year Old Subjects with Diagnosed Atopic Dermatitis.PloS one 10，e0138348，doi：10.1371/jourmal.pone.0138348(2015).
12 Draper，S.J.，Cottingham，M.G.&Gilbert，S.C.Utilizing poxviralvectored vaccines for antibody induction-progress and prospects.Vaccine 31，4223-4230，doi：10.1016/j.vaccine.2013.05.091(2013).
13 Cottingham，M.G.&Carroll，M.W.Recombinant MVA vaccines：dispellingthe myths.Vaccine 31，4247-4251，doi：10.1016/j.vaccine.2013.03.021(2013).
14 Chung，V.et al.Evaluation of safety and efficacy of p53MVA vaccinecombined with pembrolizumab in patients with advanced solid cancers.Clinical&translational oncology：official publication of the Federation of SpanishOncology Societies and of the National Caneer Institute of Mexico21，363-372，doi：10.1007/s12094-018-1932-2(2019).
15 Ishizaki，H.et al.Modified vaccinia Ankara expressing survivincombined with gemcitabine generates specific antitumor effects in a murinepancreatic carcinoma model.Cancer Immunol.Immunother.60，99-109，doi：10.1007/s00262-010-0923-0(2011).
16 Wussow，F.et al.Human cytomegalovirus vaccine based on the envelopegH/gL pentamer complex.PLoS Pathog 10，e1004524，doi：10.1371/journal.ppat.1004524(2014).
17 La Rosa，C.et al.MVA vaccine encoding CMV antigens safely inducesdurable expansion of CMV-specific T cells in healthy adults.Blood129，114-125，doi：10.1182/blood-2016-07-729756(2017).
18 Chiuppesi，F.et al.Multiantigenic Modified Vaccinia Virus AnkaraVaccine Vectors To Elicit Potent Humoral and Cellular Immune Reponses againstHuman Cytomegalovirus in Mice.Journal ofvirology 92，doi：10.1128/JVI.01012-18(2018).
19 Diamond，D.J.et al.A fifty-year odyssey：prospects for acytomegalovirus vaccine in transplant and congenital infection.Expert reviewof vaccines 17，889-911，doi：10.1080/14760584.2018.1526085(2018).
20 McFadden，G.Poxvirus tropism.Nature reviews.Microbiology 3，201-213，doi：10.1038/nrmicro1099(2005).
21 Wyatt，L.S.，Earl，P.L.&Moss，B.Generation of Recombinant VacciniaViruses.Current protocols in protein sciennce 89，51311-151318，doi：10.1002/cpps.33(2017).
22 Wang，Z.et al.Modified H5 promoter improves stability of insertgenes while maintaining immunogenicity during extended passage of geneticallyengineered MVA vaccines.Vaccine 28，1547-1557，doi：10.1016/j.vaccine.2009.11.056(2010).
23 Cottingham，M.G.et al.Recombination-mediated genetic engineering ofa bacterial artificial chromosome clone of modified vaccinia virus Ankara(MVA).PloS one 3，e1638，doi：10.1371/journal.pone.0001638(2008).
24 Wussow，F.et al.Exploiting 2A peptides to elicit potentneutralizing antibodies by a multi-subunit herpesvirus glycoproteincomplex.J.Virol.Methods 251，30-37，doi：10.1016/j.jviromet.2017.10.006(2018).
25 Wussow，F.et al.A vaccine based on the rhesus cytomegalovirus UL128complex induces broadly neutralizing antibodies in rhesus macaques.Journal ofvirology 87，1322-1332，doi：10.1128/JVI.01669-12(2013).
26 Antoine，G.，Scheiflinger，F.，Dorner，F.&Falkner，F.G.The completegenomic sequence of the modified vaccinia Ankara strain：comparison with otherorthopOxviruses.Virology 244，365-396，doi：10.1006/viro.1998.9123(1998).
27 Moss，B.Poxvirus DNA replication.Cold Spring Harbor perspectives inbiology 5，doi：10.1101/cshperspect.a010199(2013).
28 Geshelin，P.&Bems，K.I.Characterization and localization of thenaturally occurring cross-links in vaccinia virus DNA.Journal ofmolecularbiology 88，785-796，doi：10.1016/0022-2836(74)90399-4(1974).
29 Baroudy，B.M.，Venkatesan，S.&Moss，B.Incompletely base-paired flip-flop terminal loopslink the two DNA strands of the vaccinia virus genome intoone uninterrupted polynucleotide chain.Cell 28，315-324，doi：10.1016/0092-8674(82)90349-x(1982).
30 Baroudy，B.M.，Venkatesan，S.&Moss，B.Structure and replication ofvaccinia virus telomeres.Cold Spring Harbor symposia on quantitative biology47Pt2，723-729，doi：10.1101/sqb.1983.047.01.083(1983).
31 Merchlinsky，M.，Garon，C.F.&Moss，B.Molecular cloning and sequence ofthe concatemer junctionfrom vaccinia virus replicative DNA.Viral nucleasecleavage sites in cruciform structures.Journal of molecular biology 199，399-413，doi：10.1016/0022-2836(88)90613-4(1988).
32 Moyer，R.W.&Graves，R.L.The mechanism of cytoplasmic orthopoxvirusDNA replication.Cell 27，391-401，doi：10.1016/0092-8674(81)90422-0(1981).
33 DeLange，A.M.&McFadden，G.Efficient resolution of replicatedpoxvirus telomeres to native hairpin structures requires two invertedsymmetrical copies of a core target DNA sequence.Journal ofvirology 61，1957-1963(1987).
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序列表
<110> 希望之城
<120> 由天然或合成DNA产生的基于痘病毒的载体及其用途
<130> 054435-8200.CN00
<150> US 62/969,628
<151> 2020-02-03
<150> US 63/113,803
<151> 2020-11-13
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tttttttcta gacactaaat aaatagtaag attaaattaa ttataaaatt atgtatataa 60
tattaattat aaaattatgt atatgattta ctaactttag ttagataaat taataataca 120
taaattttag tatattaata ttataaatta ataatacata aattttagta tattaatatt 180
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tttttttcta gacactaaat aaatatttaa aatataatat taatatacta aaatttatgt 60
attattaatt tataatatta atatactaaa atttatgtat tattaattta tctaactaaa 120
gttagtaaat catatacata attttataat taatattata tacataattt tataattaat 180
ttaatcttac tatttattta gtgtctagaa aaaaa 215
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gtaagattaa attaattata aaattatgta tataatatta attataaaat tatgtatatg 60
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aattaataat acataaattt tagtatatta atattatatt ttaaa 165
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tttaaaatat aatattaata tactaaaatt tatgtattat taatttataa tattaatata 60
ctaaaattta tgtattatta atttatctaa ctaaagttag taaatcatat acataatttt 120
ataattaata ttatatacat aattttataa ttaatttaat cttac 165
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tttttttcta gacactaaat aaaatattta aaatataata ttaatgtact aaaacttata 60
tattattaat ttatctaact aaagttagta aattatatat ataattttat aattaattta 120
attttactaa ttttatttag tgtctagaaa aaaa 154
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tttttttcta gacactaaat aaaattagta aaattaaatt aattataaaa ttatatatat 60
aatttactaa ctttagttag ataaattaat aatatataag ttttagtaca ttaatattat 120
attttaaata ttttatttag tgtctagaaa aaaa 154
<210> 7
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<212> DNA
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<220>
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tagtaaaatt aaattaatta taaaattata tatataattt actaacttta gttagataaa 60
ttaataatat ataagtttta gtacattaat attatatttt aaat 104
<210> 8
<211> 104
<212> DNA
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<223> 痘苗病毒末端发夹环
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atttaaaata taatattaat gtactaaaac ttatatatta ttaatttatc taactaaagt 60
tagtaaatta tatatataat tttataatta atttaatttt acta 104
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tttttttcta gacactaaat 20
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atttagtgtc tagaaaaaaa 20
<210> 11
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<212> DNA
<213> 人工序列
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<223> sMVA片段1
<400> 11
ggcctagcag gccggccttt ttttctagac actaaataaa tagtaagatt aaattaatta 60
taaaattatg tatataatat taattataaa attatgtata tgatttacta actttagtta 120
gataaattaa taatacataa attttagtat attaatatta taaattaata atacataaat 180
tttagtatat taatattata ttttaaatat ttatttagtg tctagaaaaa aatgtgtgac 240
caacgaccgt aggaaactct agagggtaag aaaaatcaat cgctttatag agaccatcag 300
aaagaggttt aatatttttg tgagaccatc gaaggagaaa gagataaaac ttttttacga 360
ctccatcaga aagaggttta atatttttgt gagaccatcg aagagagaaa gagataaaac 420
ttttttacga ctccatcaga aagaggttta atatttttgt gagaccatcg aagagagaaa 480
gagataaaac ttttttacga ctccatcaga aagaggttta atatttttgt gagaccatcg 540
aaggagaaag agataaaact tttttacgac tccatcagaa agaggtttaa tatttttgtg 600
agaccatcga aggagaaaga gataaaactt ttttacgact ccatcagaaa gaggtttaat 660
atttttgtga gaccatcgaa ggagaaagag ataaaacttt tttacgactc catcagaaag 720
aggtttaata tttttgtgag accatcgaag agagaaagag ataaaacttt tttacgactc 780
catcagaaag aggtttaata tttttgtgag accatcgaag gagaaagaga taaaactttt 840
ttacgactcc atcagaaaga ggtttaatat ttttgtgaga ccatcgaaga gagaaagaga 900
ataaaaatat tttagtgaca ccatcagaaa gaggtttaat atttttgtga gaccatcgaa 960
gagagaaaga gataaaactt ttttacgact ccatcagaaa gaggtttaat atttttgtga 1020
gaccatcgaa ggagaaagag ataaaacttt tttacgactc catcagaaag aggtttaata 1080
tttttgtgag accatcgaag agagaaagag ataaaacttt tttacgactc catcagaaag 1140
aggtttaata tttttgtgag accatcgaag agagaaagag ataaaacttt tttacgactc 1200
catcagaaag accatcgaag agagaaagag aaagagatag ttagtctaga tatttttctt 1260
agtacaaaag tcaatgtttt aaaatatatg gacaagaatt tgtctgtata aaaacttgtg 1320
tgaaattttg taccaaagaa aaaatgtgag cagtatcccc tacatggatt ttactagatc 1380
atttatatac caaaaaatat tatacgatct acgttttatt atatgatttt aacgtgtaaa 1440
ttataaacat tattttatga tatacaattg tctggtaacc tagatgggca taggggatga 1500
gtatatgttg ttggacgtta ttgtttaaga aatagttgat gcatcagaaa gaggtttaat 1560
atttttgtga gaccatcgaa gagagaaaga gataaaactt ttttacgact ccatcagaaa 1620
gaggtttaat atttttgtga gaccatcgaa gagagaaaga gataaaactt ttttatgact 1680
ccattgaaga gagaatgaga ataaaaatat tttagtgaca ccatcagaaa gaggtttaat 1740
attttttatg agaccatcaa agagagaaag agaataaaaa tattttatga ctccattgaa 1800
gagagaaaga gaaaatgaga ataaaaatat tttagtgaca ccatcagaaa gaggtttaat 1860
attttttatg agaccatcaa agagagaaag agaataaaaa tatttttgta aaactttttt 1920
tatgagacca tcaaagagag aaagagaata aaaatatttt tgtaaaactt tttttatgag 1980
accatcaaag agagaaagag aataaaaata tttttgtaaa acttttttta tgagaccatc 2040
aaagagagaa agagaataaa aatatttttg taaaactttt tttatgagac catcaaagag 2100
agaaagagaa taaaaatatt tttgtaaaac tttttttatg agaccatcaa agagagaaag 2160
agaataaaaa tatttttgta aaactttttt tatgagacca tcaaagagag aaagagaata 2220
aaaatatttt tgtaaaactt tttttatgag accatcaaag agagaaagag aataaaaata 2280
ttttatgact ccattgaaga gagaaagaga ataaaaatat tttagtgaca ccatcagaaa 2340
gaggtttaat atttttgtga gaccatcgaa gagagaaaga gaataaaaat attttatgac 2400
tccattgaag agagaaagag aataaaaata ttttagtgac accatcagaa agaggtttaa 2460
tattttttat gagaccatca aagagagaaa gagaataaaa atatttttgt aaaacttttt 2520
ttatgagacc atcaaagaga gaaagagaat aaaaatattt ttgtaaaact ttttttatga 2580
gaccatcaaa gagagaaaga gaataaaaat atttttgtaa aacttttttt atgagaccat 2640
caaagagaga aagagaataa aaatattttt gtaaaacttt ttttatgaga ccatcaaaga 2700
gagaaagaga ataaaaatat ttttgtaaaa ctttttttat gagaccatca aagagagaaa 2760
gagaataaaa atattttatg actccattga agagagaatg agaataaaaa tattttagtg 2820
acaccatcag aaagaggttt aatatttttg tgagaccatc gaagagagaa agagaataaa 2880
aatattttat gactccattg aagagagaaa gagaataaaa atattttagt gacaccatca 2940
gaaagaggtt taatattttt tatgagacca tcaaagagag aaagagaata aaaatatttt 3000
tgtaaaactt tttttatgag accatcaaag agagaaagag aataaaaata tttttgtaaa 3060
acttttttta tgagaccatc aaagagagaa agagaataaa aatatttttg taaaactttt 3120
tttatgagac catcaaagag agaaagagaa taaaaatatt tttgtaaaac tttttttatg 3180
agaccatcaa agagagaaag agaataaaaa tatttttgta aaactttttt tatgagacca 3240
tcaaagagag aaagagaata aaaatatttt tgtaaaactt tttttatgag accatcaaag 3300
agagaaagag aataaaaata tttttgtaaa acttttttta tgagaccatc aaagagagaa 3360
agagaataaa aatattttat gactccattg aagagagaat gagaataaaa atattttagt 3420
gacaccatca gaaagaggtt taatattttt gtgagaccat cgaagagaga aagagaataa 3480
aaatatttta tgactccatt gaagagagaa tgagaataaa aatattttag tgacaccatc 3540
agaaagaggt ttaatatttt ttatgagacc atcaaagaga gaaagagaat aaaaatattt 3600
ttgtaaaact ttttttatga gaccatcaaa gagagaaaga gaataaaaat atttttgtaa 3660
aaattataaa cattatttta tgatatacaa ttgtctggta acctagatgg gcatagggga 3720
tgttgataag ctcgacgagt atatgttgtt ggacgttatt gtttaagaaa tagttgatgc 3780
atcagaaaga gaataaaaaa tattttagtg agaccatcga agagagaaag agataaaact 3840
tttttacgac tccatcagaa agaggtttaa tatttttgtg agaccatcga agagagaaag 3900
agataaaact tttttacgac tccatcagaa agaggtttaa tatttttgtg agaccatcga 3960
aggagaaaga gataaaactt ttttacgact ccatcagaaa gaggtttaat atttttgtga 4020
gaccatcaaa gagagaaaga gaataaaaat atttttgtaa aacttttttt atgagaccat 4080
caaagagaga aagagaataa aaatattttt gtaaaacttt ttttatgaga ccatcaaaga 4140
gagaaagaga ataaaaatat ttttgtaaaa ctttttttat gagaccatca aagagagaaa 4200
gagaataaaa atatttttgt aaaacttttt ttatgagacc atcaaagaga gaaagagaat 4260
aaaaatattt tatgactcca ttgaagagag aatgagaata aaaatatttt agtgacacca 4320
tcagaaagag gtttaatatt tttgtgagac catcgaagag agaaagagaa taaaaatatt 4380
ttatgactcc attgaagaga gaatgagaat aaaaatattt tagtgacacc atcagaaaga 4440
ggtttaatat tttttatgag accatcaaag agagaaagag aataaaaata tttttgtaaa 4500
acttttttta tgagaccatc aaagagagaa agagaataaa aatatttttg taaaactttt 4560
tttatgagac catcaaagag agaaagagaa taaaaatatt tttgtaaaac tttttttatg 4620
agaccatcaa agagagaaag agaataaaaa tatttttgta aaactttttt tatgagacca 4680
tcaaagagag aaagagaata aaaatatttt atgactccat tgaagagaga atgagaataa 4740
aaatatttta gtgacaccat cagaaagagg tttaatattt ttgtgagacc atcgaagaga 4800
gaaagagaat aaaaatattt tatgactcca ttgaagagag aaagagaata aaaatatttt 4860
agtgacacca tcagaaagag gtttaatatt ttttatgaga ccatcaaaga gagaaagaga 4920
ataaaaatat ttttgtaaaa ctttttttat gagaccatca aagagagaaa gagaataaaa 4980
atattttatg actccattga agagagaatg agaataaaaa tattttagtg acaccatcag 5040
aaagaggttt aatatttttg tgagaccatc gaagagagaa agagaataaa aatattttat 5100
gactccattg aagagagaat gagaataaaa atattttagt gacaccatca gaaagaggtt 5160
taatattttt gtgagaccat cgaagagaga aagagaataa aaatatttta tgactccatt 5220
gaagagagaa tgagaataaa aatattttag tgacaccatc agaaagaggt ttaatatttt 5280
ttatgagacc atcaaagaga gaaagagaat aaaaatattt ttgtaaaact ttttttatga 5340
gaccatcaaa gagagaaaga gaataaaaat atttttgtaa aacttttttt atgagaccat 5400
caaagagaga aagagaataa aaatattttt gtaaaacttt ttttatgaga ccatcaaaga 5460
gagaaagaga ataaaaatat ttttgtgaga ccatcaaaga gagaaagaga ataaaaatat 5520
ttttgtgaga ccatcaaaga gagaaagaga ataaaaatat ttttgtgaga ccatcaaaga 5580
gagaaagaga ataaaaatat tttatgactc cattgaagag agaaagagaa taaaaatatt 5640
ttagtgacac catcagaaag aggtttaata tttttgtgag accatcgaag agagaaagag 5700
aataaaaata ttttatgact ccattgaaga gagaaagaga ataaaaatat tttagtgaca 5760
ccatcagaaa gaggtttaat attttttatg agaccatcaa agagagaaag agaataaaaa 5820
tattttttat gagaccatca aagagagaaa gagaataaaa atattttatg agaccatcaa 5880
agagagaaag agaataaaaa tattttttat gagaccatca aagagagaaa gagaataaaa 5940
atattttatg agaccatcaa agagagaaag agaataaaaa tattttttat gagaccatca 6000
aagagagaaa gagaataaaa atatttttgt atgagaccat cagaaagagg tttaatattt 6060
ttgtgatacc ctgaaaggaa ataggaatag tgtcataatc gtatcacact attgagacag 6120
aaaaagaaga agtcgcgaga ggtaactttt tgttttgcaa accggaatat agtgtccggt 6180
acactttttt aattcgtggt gtgcctgaat cgttcgatta accctactca tccaatttca 6240
gatgaataga gttatcgatt cagacacacg ctttgagttt tgttgaatcg atgagtgaag 6300
tatcatcggt tgcaccttca gatgccgatc cgtcgacata cttgacctca agttcagatg 6360
attccttgca catgtctccg atacgaacgc taaactctag attcttgaca cattttgtat 6420
cgacgatcgt tgaaccgatg atatcttcgt aactcacttt cttatgagag atgttagacc 6480
cgagtactgg atgggtcttg atgtcgctgt ctttctcttc ttcgctacat ctgatgtcga 6540
tagacacctc acagtctttc catcagcgga ttctgagatg gatttaatct gaggacattt 6600
ggtgaatcca aagttcattc tcagacctcc accgatgatg gagtaataag tggtaggagg 6660
atctacatcc tcgactgatt ccacctcggg atctggatct gactcggact ctgtaatttc 6720
cgttacggat tggcaaatct tatcatcggt cggtgtttgg tcttgctttg tgactttgat 6780
aataacatcg attcccatat gatgtttgtt ttcttcttcc gtacacgatg aggatgattg 6840
ctgaagactg gcaggcacat gcatgccagt acgatatatt gtttcatgat tgctattgat 6900
tgagtactgt tctttatgat tctacttcct taccgtgcaa taaattagaa tatattttct 6960
acttttacga gaaattaatt attgtattta tgggtgaaaa acttactata aaaagcgggt 7020
gggtttggaa ttagtgatca gtttatgtat atcgcaacta ccgggcatat ggctacatta 7080
cccacatgat aagagattgt atcagtttcg tagtcttgag tattggtatt actatatagt 7140
atatagatgt cgacgctaga gttactgtct ccgaatgcgg catgatagta tcattctttg 7200
ctttcgttaa ctgtttggag gaagaatctt tgttattgca tttaatctcg aaattcagag 7260
tgcacacctt tctcctgtaa agaaacctga agtcgctacc ttattaagaa gacgggatcg 7320
cagtctttat gattcatagt aatagttagt tccgacgttg agatggattc gctgagaccg 7380
gtagtggtcg tccgagtaca cgatgtgtcg ttaactggat acaggttaat ttccacatcg 7440
atatagttaa aggtatttct gggtacgggt tcgcatttat ctgcggaaga gacggtgtga 7500
gaatatgttc cgagaccaca cggagaacag atgacgtctc cggatactcc gtatcctatt 7560
ccacattttg tttgggaaac acatgccttg catccatgat cgggagagca ttcacagatt 7620
ctattgtgag tcgtgttaca cgatcgcgtc gacattgttg acagaaacgt gaccttcatt 7680
cttaccgtcg tccataaata cgttaggtat gtaccacata ctgtcgcgaa cgatgcgtcc 7740
atctcataat gatttacttt ttcataatta aagatgtgaa agaaaaccga acaatatatt 7800
tttttagtaa tgtttatgcg agacatataa aataaactcc gtgtttatga tgccggtaaa 7860
tgtttttatc atcttggacg gaatcgattt tgtaatatgc catggaaaca ggacattatc 7920
actccatgat aaattattta atggagtcga tcctctcatt gttctttgcg tatctcaatc 7980
tgtggcgttt gcttcgttta aataatatat caaacatgga gacgcctgat atgtaggcat 8040
tcttcattct attaatgtct gctctatagc gctttagttc cttatgacga ccggcgatat 8100
catacttact ttagaaggaa aatcatcatc taggattaag gcgtatctga tacaggcgaa 8160
taatggttca ggatatagat agcgtatatc tctattaaat gcgtcaatca tagtctctag 8220
agtgggatgg taactcagta ataaatcaac tagcttctct ttggtaactg cttttctgga 8280
tggccgtatt gattatcgag cgtgacactc gctccatatt ccaataaccg ctttgcaaat 8340
tgtatattat tgacatcgac cgcgtaatat agtagagtta tcgatcatat ctatatcatc 8400
catgtacttg cttagtatat caaatacatc ttcataacag tgatacccgc aattattaaa 8460
tctcgataat atcagaccgt acatacatag acggccattg ttagatatgt gatttacagc 8520
cgcgtgtcca tattttccac gataaacctt acgacgttta catcgacgag attattatta 8580
acaaagttgt tgtccgtcgt cttatccaac atgcattgaa tgataggtat acttaccata 8640
tcgccgtaat gtaagtagtt tatcagtatg gcttgtacga tggattcatc ctgttgtcta 8700
aatctcttta gaatgttatc gatgatgtag tggttatatt ctctggaatc gtacgaagta 8760
atactacgca ttacgtcgac aagagtatga cgtctctcaa taagaagatt aacgatttcc 8820
atgtctacat tatatggggt tactctaaat cgcttgttta gataatacgc ctctaatata 8880
gggctgacgt cgtatactct acacgtgtcc acatccttta ttaataatct ctatatctat 8940
ggttgagcaa gaccagtagt attggatgga aacattgtta tcgatcaaac atttaattac 9000
atccttggat agagattctc tatgagacga tatatagtaa tgaagagagt tcttacacat 9060
atcactgttg tacatacagg tacgaaatac gtaaccggtg ctgtaacatt ctgatttaag 9120
aagccatagc aatacttctg gtctcggatt aggcgtcgtt acgtatatat ccaccaatcc 9180
gagaccattg attgcataat tcgtattctt ggacggacgt atccgtttat ccacaattag 9240
gtattttagc agacgtaagt cgaaatcatt tatattcgac ttgagttcgt tagaggaatt 9300
cgaatagctg gatatcagta gatgcacaat ctgagatttt acgtatctat gcttactgta 9360
tgctcctagc ggagttaatc cttcgttgtt tctacaaagt ctctcgactc cgcgagagag 9420
taacagtcga acaatcttaa tgtctgtatc gcatttattg gagacgtaac aatgtagcgc 9480
attgtttcct cgtctatcta tatgttttga taagttgtga cacgtttcaa tttctagttt 9540
tatttttttg tacgtcacat cttcatccag tagacgacat agaatacatg tgcaatccat 9600
agctattctg gtgctaatta ttcctcataa gatgataaaa agtgtagtga gagagcatga 9660
aggagattta gtatttagca gtgcggatat gatccaagag ggtgagatag tcgttctcgt 9720
tcagaatctt tcgcagcata agtagtatgt cgatatactt atcgttgaag actcttccag 9780
agacgatagc tgattgagta caaagtccaa tgattgcacg aagttcttcg gcggttttca 9840
tggagtcatt tctgatgaaa catttaatga tctaaatttc agtttatgtt tgtaccccgt 9900
attcatactt aacaaattgg tattacatac cattaataat gcaagcataa aaaatcgtta 9960
gtagatgttt ctaaatatag gttccgtaag caaagaatat aagaatgaag cggtaatgat 10020
aaaatcaatc gttatctaaa atgatcatac tcatttattt tattctatta tattaacaca 10080
tacattttta acagcaacac attcaatatt gtattgttat ttttatatta tttacacaat 10140
taacaatata ttattagttt atattactga attaataata taaaattccc aatcttgtca 10200
taaacacaca ctgagaaaca gcataaacac aaaatccatc aaaaatgttg ataaattatc 10260
tgatgttgtt gttcgctgct atgataatca gatcattcgc cgatagtggt aacgctatcg 10320
aaacgacatc gccagaaatt acaaacgcta caacagatat tccagctatc agattatgcg 10380
gtccagaggg agatggatat tgtttacacg gtgactgtat ccacgctaga gatatcgacg 10440
gtatgtattg tagatgctct catggttata caggcattag atgtcagcat gtagtattag 10500
tagactatca acgttcagaa aaaccaaaca ctacaacgtc atatatccca tctcccggta 10560
ttatgcttgt attagtaggc attattatta ttacgtgttg tctattatct gtttataggt 10620
tcactcgacg aactaaacta cctatacaag atatggttgt gccataattt ttataaattt 10680
tttttatgag tatttttaca aaaatgtata aagtgtatgt cttatgtata tttataaaaa 10740
tgctaaatat gcgatgtatc tatgttattt gtatttatct aaacaatacc tctacctcta 10800
gatattatac aaaaattttt tatttcggca tattaaagta aaatctagtt accttgaaaa 10860
tgaatacagt gggtggttcc gtatcaccag taagaacata atagtcgaat acagtatccg 10920
attgagattt tgcatacaat actagtctag aaagaaattt gtaatcatct tctgtgacgg 10980
gagtccatat atctgtatca tcgtcccatg ctatattcct gttatcatca ttagttaatg 11040
aaaataactc tcgtgcttca gaaaagtcaa atattgtatc catacataca tctccaaaac 11100
tatcgcttat acgtttatct ttaacgatac ctatacctag atggttattt actaacagac 11160
attttccaga tctattgact ataactccta tagtttccac atcaaccaag taatgatcat 11220
ctattgttat ataacaataa cataactctt ttccgttttt atcagtatgt atatctatat 11280
caacgtcgtc gttgtagtga atagtagtca ttgatctatt atatgaaacg gatatgtcta 11340
gaacggcaat tgttttacgt ccagttaaca ctttcgttga tttaaagtct agagtctttg 11400
caaacataat atccttatcc gactttatat ttcctgtagg gtggtataat tttattttgc 11460
ctccacatat cggtgtttcc aaatatatta ctagacaata ttccatatag ttattagtta 11520
agggtaccca attagaacac gtacgcttat tatcatcatt tggatcgtat ttcataaaag 11580
ttattgtact atcgatgtca acacattcta cattttttaa tcgtctatat agtatttttc 11640
tgatattttc tataatatca gaattgtctt ccatcggaag ttgtatacta tcggaatcag 11700
ttacatgttt aaataattct ctgatgtcat tccttataca atcaaattca ttattaaaca 11760
gtttaatagt ctgtagacct ttatcgtcgt aaatatccat tgtcttatta gttacgctta 11820
tttttatgtg tttttacgtt gctttattat attttataag aatgattgtt tgacgaatca 11880
cgagaactat taagacacat tattaggtat atattataaa aaagtttttg attacgatgt 11940
tataagagga aagaggacac attaacatca tacatcaatt aactacattc ttataacatc 12000
gtaatcaaaa gaattgcaat tttgatgtat aacaactgtc aatgggttat ggaattgtat 12060
attacatatt atacggtatg ttggtaacga caaataccga tcggtaattg tctgccggtg 12120
taatagaatt atatatatct atctattaca ccggccttgt atacataata ataagttgtg 12180
gtagtatgat ctccatattt ataatttagg actttgtatt cagttttttt ggaatcataa 12240
aaaataaaaa aaagttttac taatttaaaa ttatttacat ttttttcact gtttagtcgc 12300
ggatatggaa ttcgatcctg ccaaaatcaa tacatcatct atagatcatg taacaatatt 12360
acaatacata gatgaaccaa atgatataag actaacagta tgcattatca caaaaataaa 12420
tccacatttg gctaatcaat ttcgggcttg gaaaaaacgt atcgccggaa gggactatat 12480
gactaactta tctagagata caggaataca acaatcaaaa cttactgaaa ctgtcaaaaa 12540
aatagaaaca tatatggtct atatatacac tacaatttag ttattaattg gataaccgat 12600
gtgattatca atcaatatta agaaggttgg taaattggta catagctaat aatacctata 12660
cacccaataa tacaacaacc atttctgagt tggatatcat caaaatactg gataaatacg 12720
aggacgtgta tagagtaagt aaagaaaaag aatgtgaaat ttgctatgaa gttgtttact 12780
caaaacgata gatactttgg tttattggat tcgtgtaatc atatattttg cataacatgc 12840
atcaatatat ggcatagaac acgaagagaa accggtgcgt cggataattg tcctatatgt 12900
cgtacccgtt ttagaaacat aacaatgagc aagttaacta ataaataaaa agtttaattt 12960
gttgacgacg tatgtcgtta ttttttctcg tataaaagat taatttgatt ctaatataat 13020
ctttagtatt ggataaatat caattcaaat taattccatt agattatatc ataaataaaa 13080
atagtagcac gcactacttc agccaaatat tcttttttga aacgccatct atcgtagtga 13140
ggacacaagt gaacctataa tgagcaaatt tattagtatc ggttacatga aggactttac 13200
gtagagtggt gattccacta tctgtggtac gaacggtttc atcttctttg atgccatcac 13260
ccagatgttc tataaacttg gtatcctttg ccaaccaata catatagcta aactcaggca 13320
tatgttccac acatcctgaa caatgaaatt ctccagaaga tgttacaatg tctagatttg 13380
gacatttggt ttcaaccgcg ttaacatatg agtgaacaca cccatacatg aaagcgatga 13440
gaaataggat tttcatcttg ccaaaatatc actagaaaaa atttatttat caattttaaa 13500
ggtataaaaa atacttattg ttgctcgaat attttgtatt tgatggtata cggaagatta 13560
gaaatgtagg tattatcatc aactgattct atggttttat gtattctatc atgtttcact 13620
attgcgttgg aaataatatc atatgcttcc acatatattt tattttgttt taactcataa 13680
tactcacgta attctggatt attgacatat ctatgaataa ttttagctcc atgatcagta 13740
aatattaatg agaacatagt attaccacct accattattt ttttcatctc attcaattct 13800
taattgcaaa gatctatata atcattatag cgttgactta tggactctgg aatcttagac 13860
gatgtacagt catctataat catggcatat ttaatacatt gttttatagc atagtcgtta 13920
tctacgatgt tagatatttc tctcaatgaa tcaatcacac aatctaatgt aggtttatga 13980
cataatagca ttttcagcag ttcaatgttt ttagattcgt tgatggcaat ggctatacat 14040
gtatatccgt tatttgatct aatgttgaca tctgaaccgg attctagcag taaagatact 14100
agagattgtt tattatatct aacagccttg tgaagaagtg tttctcctcg tttgtcaatc 14160
atgttaatgt ctttaagata aggtaggcaa atgtttatag tactaagaat tgggcaagca 14220
taagacatgt cacaaagacc ctttttgtat gtataagtgt aaaaattata acattcatag 14280
ttggatttac ataggtgtcc aatcgggatc tctccatcat cgagataatt gatggcatct 14340
cccttccttt tttagtagat atttcatcgt gtaagaatca atattaatat ttctaaagta 14400
tccgtgtata gcctctttat ttaccacagt tccatattcc actagaggga tatcgccgaa 14460
tgtcatatac tcaattagta tatgttggag gacatccgag ttcattgttt tcaatatcaa 14520
aaagatggtt tccttatcat ttctccatag tggtacaata ctacacatta ttccgtgcgg 14580
ctttccattt tccaaaaaca atttgaccaa atctacatct ttattgtatc tataatcact 14640
atttagataa tcagccataa ttactcgagt gcaacatgtt agatcgtcta tatatgaata 14700
agccgtgtta tctattcctt tcattaacaa tttaacgatg tctatatcta tatgagatga 14760
cttaatataa tattgaagag ctgtacaata gtttttatct ataaaagacg gcttgattcc 14820
gtgattaatt agacatttaa caacttccgg acgcacatat gctctcgtat ccgactctga 14880
atacagatga gagatgatat acagatgcaa tacggtaccg caatttcgta gttgataatc 14940
atcatacgcg tatcagtact cgtcctcata aagaacactg cagccatttt ctatgaacaa 15000
atcaataatt tcaggaacag gatcatctgt cattacataa ttttctataa ctgaacgatg 15060
gttttcacat ttaacactca agtcaaatcc atgttctacc aacaccttta tcaagtcaac 15120
gtctacattt ttggatttca tatagctgaa tatattaaag tcatttatgt tgctaaatcc 15180
agtggcttct agtagagcca tcgctatatc ctttaacttt aacatgtcta ctatttgtgt 15240
attcttctaa tggggtagct gtctccaatt tttgcgtaat ggattagtgc cactgtctag 15300
tagtagtttg acgacctcga cattattaca atgctcatta aaaaggtatg cgtgtaaagc 15360
attattcttg aattggttcc tggtatcatt aggatctctg tctctcaaca tctgtttaag 15420
ttcatcgaga gccacctcct cattttccaa atagtcaaac attttgactg aatgagctac 15480
tgtgaactct atacacccac acaactaatg tcattaaata tcatgtcaaa aacttgtaca 15540
attattaata aaaataattt agtgtttaaa ttttaccagt tccagatttt acacctccgt 15600
taaccccact ttttacacca ctggacgatc ctcctcccca cattccaccg ccaccagatg 15660
tataagtttt agatccttta ttactaccat catgtccatg gataaagaca ctccacatgc 15720
cgccactacc ccctttagaa gacatattaa taagacttaa ggacaagttt aacaataaaa 15780
ttaatcacga gtaccctact accaacctac actattatat gattatagtt tctattttta 15840
cagtacctta actaaagtct ctagtcacaa gagcaatact accaacctac actattatat 15900
gattatagtt tctattttta taggaacgcg tacgagaaaa tcaaatgtct aatttctaac 15960
ggtagtgttg ataaacgatt atcgtcaatg gatacctcct ctatcatgtc gtctattttc 16020
ttactttgtt ctattaactt attagcatta tatattattt gattataaaa cttatattgc 16080
ttattagccc aatctgtaaa tatcggatta ttaacatatc gtttctttgt aggtttattt 16140
aacatgtaca tcactgtaag catgtccgta ccatttattt taatttgacg catatccgca 16200
atttcttttt cgcagtcggt tataaattct atatatgatg gatacatgct acatgtgtac 16260
ttataatcga ctaatatgaa gtacttgata catattttca gtaacgattt attattacca 16320
cctatgaata agtacctgtg atcgtctagg taatcaactg ttttcttaat acattcgatg 16380
gttggtaatt tactcagaat aatttccaat atcttaatat ataattctgc tatttctggg 16440
atatatttat ctgccagtat aacacaaata gtaatacatg taaacccata ttttgttatt 16500
atattaatgt ctgcgccatt atctattaac cattctacta ggctgacact atgcgactta 16560
atacaatgat aaagtatact acatccatgt ttatatcatc aatatacggc ttacaaagtt 16620
ttagtatcga taacacatcc aactcacgca tagagaaggt agggaataat ggcataatat 16680
ttattaggtt atcatcattg tcattatcta caactaagtt tccatttttt aaaatatact 16740
cgacaacttt aggatctcta ttgccaaatt tttgaaaata tttatttata tgcttaaatc 16800
tatataatgt agctccttca tcaatcatac atttaataac attgatgtat actgtatgat 16860
aagatacata ttctaacaat agatcttgta tagaatctgt atatctttta agaattgtgg 16920
atattattac gtaaactatt acacaattct aaaatataaa acgtatcacg gtcgaataat 16980
agttgatcaa ctatataatt atcgattttg tgatttttct tcctaaactg tttacgtaaa 17040
tagttagata gaatattcat tagttcatga ccactatagt tactatcgaa taacgcgtca 17100
aatatttccc gtttaatatc gcatttgtca agataataat agagtgtggt atgttcacga 17160
taagtataat aacgcatctc tttttcgtgt gaaattaaat agtttattac gtccaaagat 17220
gtagcataac catcttgtga cctagtaata atataataat agagaactgt tttacccatt 17280
ctatcatcat aatcagtggt gtagtcgtaa tcgtaattgt ctaattcatc atcccaatta 17340
taatattcac cagcacgtct aatctgttct attttgatct tgtatccata ctgtatgttg 17400
ctacatgtag gtattccttt atccaataat agtttaaaca catctacatt gggatttgat 17460
gttgtagcgt atttttctac aatattaata ccatttttga tactatttat ttctatacct 17520
ttcgaaatta gtaatttcaa taagtctata tcgatgttat cagaacatag atattcgagt 17580
atatcaaaat cattgatatt tttatagtcg actgacgaca ataacaaaat cacaacatcg 17640
tttttgatat tattattttt cttggtaacg tatgccttta atggagtttc accatcatac 17700
tcatataatg gatttgcacc actttctatc aatgattgtg cactgctggc atcgatgtta 17760
aatgttttac aactatcata gagtatctta tcgttaacca tgattggttg ttgatgctat 17820
cgcatttttt ggtttctttc atttcagtta tgtatggatt tagcacgttt gggaagcatg 17880
agctcatatg atttcagtac tgtagtgtca gtactattag tttcaataag atcaatctct 17940
agatctatag aatcaaaaca cgataggtca gaagataatg aatatctgta ggcttcttgt 18000
tgtactgtaa cttctcgttt tgttagatgt ttgcatcgtg ctttaacatc aatggtacaa 18060
attttatcct cgctttgtgt atcatattcg tccctactat aaaattgtat attcagatta 18120
tcatgagatg tgtatacgct aacggtatca ataaacggag cacaccattt agtcataacc 18180
gtaatccaaa aatttttaaa gtatatctta acgaaagaag ttgtgtcatt gtctacggtg 18240
tatggtacta gatcctcata agtgtatata tctagagtaa tgtttaattt atcaaatggt 18300
tgataatatg gatcctcatg acaatttccg aagatggaaa tgagatatag acatgcaata 18360
aatctaattg cggacatggt tactccttaa aaaaatacga ataatcacct tggctattta 18420
gtaagtgtca tttaacacta tactcatatt aatccatgga ctcataatct ctatacggga 18480
ttaacggatg ttctatatac ggggatgagt agttttcttc tttaacttta tactttttac 18540
taatcatatt tagactgatg tatgggtaat agtgtttaaa gagttcgttc tcatcatcag 18600
aataaatcaa tatctctgtt tttttgttat acagatgtat tacagcctca tatattacgt 18660
aatagaacgt gtcatctacc ttattaactt tcaccgcata gttgtttgca aatacggtta 18720
atcctttgac ctcgtcgatt tccgaccaat ctgggcgtat aatgaatcta aactttaatt 18780
tcttgtaatc attcgaaata atttttagtt tgcatccgta gttatcccct ttatgtaact 18840
gtaaatttct caacgcgata tctccattaa taatgatgtc gaattcgtgc tgtataccca 18900
tactgaatgg atgaacgaat accgacggcg ttaatagtaa tttacttttt catctttaca 18960
tattgggtac tagttttact atcataagtt tataaattcc acaagctact atggaataag 19020
ccaaccatct tagtataaca cacatgtctt aaagtttatt aattaattac atgttgtttt 19080
atatatcgct acgaatttaa acagagaaat cagtttagga aaaaaaaata tctatctaca 19140
tcatcacgtc tctgtattct acgatagagt gctactttaa gatgagacat atccgtgtca 19200
tcaaaaatat actccattaa aatgattatt ccggcagcga acttgatatt ggatatatca 19260
caacctttgt taatatctac gacaatagac agcagtccca tggttccata aacagtgagt 19320
ttatctttct ttgaagagat attttgtaga gatcttataa aactgtcgaa tgacatcgca 19380
tttatatctt tagctaaatc gtatatgtta ccatcgtaat atctaaccgc gtctatctta 19440
aacgtttcca tcgctttaaa gacgtttccg atagatggtc tcatttcatc agtcatactg 19500
agccaacaaa tataatcgtg tataacatct ttgatagaat cagactctaa agaaaacgaa 19560
tcggctttat tatacgcatt catgataaac ttaatgaaaa atgtttttcg ttgtttaagt 19620
tggatgaata gtatgtctta ataattgtta ttatttcatt aattaatatt tagtaacgag 19680
tacactctat aaaaacgaga atgacataac tagttatcaa agtgtctagg acgcgtaatt 19740
ttcatatggt atagatcctg taagcattgt ctgtattctg gagctatttt ctctatatct 19800
aatttctgaa cgttcaccaa tgtctctagc cactttggca ctaatagcga tcattcgctt 19860
agcgtcttct atattattaa ctggttgatt caatctatct agcaatggac cgtcggacag 19920
cgtcattctc atgttcttaa tcaatgtaca tacatcgccg tcatctacca attcatccaa 19980
caacataagc tttttaaaat catcattata ataggtttga tcgttgtcat ttctccaaag 20040
aatatatcta ataagtagag tcctcatgat tagttaacaa ctatttttta tgttaaatca 20100
attagtacac cgctatgttt aatacttatt catattttag tttttaggat tgagaatcaa 20160
tacaaaaatt aatgcatcat taattttaga aatacttagt ttccacgtag tcaatgaaac 20220
atttgaactc atcgtacagg acgttctcgt acaggacgta actataaacc ggtttatatt 20280
tgttcaagat agatacaaat ccgataactt tttttacgaa ttctacggga tccactttaa 20340
aagtgtcata ccgggttctt tttatttttt taaacagatt aatggtgtga tgttgattag 20400
gtcttttacg aatttgatat agaatagcgt ttacatattc tccataatgg tcaatcgcca 20460
tttgttcgta tgtcataaat tctttaatta tatgacactg tgtattattt agttcatcct 20520
tgttcatcat taggaatcta tccaatatgg caattatact agaactatag gtgcgttgta 20580
tacacatatt gatgtgtctg tttatacaat ccatgctact accttcgggt aaaattgtag 20640
catcatatac catttctagt actttaggtt cattgttatc cattgcagag gacgtcatga 20700
tcgcatccta aaaaaatata ttatttttat gttattttgt taaaaataat catcgaatac 20760
gaatcatcca gtccactgaa tagcaaaatc tttactattt tggtatcttc caatgtggct 20820
gcctgatgta atggaaattc attctctaga agatttttca atgctccagc gttcaacaac 20880
gtacatacta gacgcacgtt attatcagct attgcataat acaaggcact atgtccatgg 20940
acatccgcct taaatgcatc tttgctagag agaaagcttt tcagctgctt agacttccaa 21000
gtattaattc gtgacagatc catgtctgaa acgagacgct aattagtgta taatttttgt 21060
catattgcac cagaattaat aatatctcta atagatctga ttagtagata catggctatc 21120
gcaaaacaac atatacacat ttaataaaaa taatatttat taagaaaatt cagatttcac 21180
gtacccatca atataaataa aataatgatt ccttacaccg tacccatatt aaggagattc 21240
taccttaccc ataaacaata taaatccagt aatatcatgt ctgatgatga acacaaatgg 21300
tgtattaaat tccagttttt caggagatga tctcgccgta gctaccataa tagtagatgc 21360
ctctgctaca gttccttgtt cgtcgacatc tatctttgca ttctgaaaca ttttataaat 21420
atataatggg tccctagtca tatgtttaaa cgacgcatta tctggattaa acatactagg 21480
agccatcatt tcggctatcg acttaatatc cctcttattt tcgatagaaa atttagggag 21540
tttaagattg tacactttat tccctaattg aaacgaccaa tagtctaatt ttgcagccgt 21600
aatagaatct gtgaaatggg tcatattatc acctattgcc aggtacatac taatattagc 21660
atccttatac ggaaggcgta ccatgtcata ttctttgtca tcgattgtga ttgtatttcc 21720
ttgcaattta gtaactacgt tcatcatggg aaccgttttc gtaccgtact tattagtaaa 21780
actagcattg cgtgttttag tgatatcaaa cggatattgc catatacctt taaaatatat 21840
agtattaatg attgcccata gagtattatt gtcgagcata ttagaatcta ctacattaga 21900
cataccggat ctacgttcta ctatagaatt aattttatta accgcatctc gtctaaagtt 21960
taatctatat aggccgaatc tatgatattg ttgataatac gacggtttaa tacacacagt 22020
attatctacg aaactttgat aagttagatc agtgtacgta tatttagatg ttttcagctt 22080
agctaatcct gatattaatt ctgtaaatgc tggacccaga tctctttttc tcaaatccat 22140
agtcttcaat aattctattc tagtattacc tgatgcaggc aatagcgaca taaacataga 22200
aaacgaataa ccaaacggtg agaagacaat attatcatct tgaatatttt tatacgctac 22260
tataccggca ttggtaaatc cttgtagacg ataggtagac gctgaacacg ttaacgatag 22320
tatcaataac gcaatcatga ttttatggta ttaataatta accttatttt tatgttcggt 22380
ataaaaatta ttgatgtcta cacatccttt tgtaattgac atctatatat ccttttgtat 22440
aatcaactct aatcacttta acttttacag ttttccctac cagtttatcc ctatattcaa 22500
catatctatc catatgcatc ttaacactct ctgccaagat agcttcagag tgaggatagt 22560
caaaaagata aatatataga gcataatcat tctcgtatac tctgcccttt attacatcgc 22620
ccgcattggg caacgaataa caaaatgcaa gcatcttgtt aacgggctcg taaattggga 22680
taaaaattat gtttttatat ctattttatt caagagaata ttcaggaatt tctttttccg 22740
gttgtatctc atcgcagtat atatcatttg tacattgttt catatttttt aatagtttac 22800
accttttagt aggactagta tcgtacaatt catagctgta ttttgaattc caatcacgca 22860
taaaaatatc ttctaattgt tgacgaagac ctaatccatc atccggtgta atattaatag 22920
atgctccaca tgtatccgta aagtaatttc ctgtccaatt tgaggtacct atataggccg 22980
ttttatcggt taccatatat ttggcatggt ttaccctaga atacggaatg ggaggatcag 23040
catctggtac aataaatagc tttacttcta tatttatgtt tttagatttt agcatagcga 23100
tagatcttaa aaagtttctc atgataaacg aagatcgttg ccagcaacta atcaatagct 23160
taacggatac ttgtctgtct atagcggatc ttcttaattc atcttctata taaggccaaa 23220
acaaaatttt acccgccttc gaataaataa tagggataaa gttcataaca gatacataaa 23280
cgaatttact cgcatttcta atacatgaca ataaagcggt taaatcattg gttctttcca 23340
tagtacatag ttgttgcggt gcagaagcaa taaatacaga gtgtggaaca ccacttacgt 23400
taatactaag aggatgatct gtattataat acgacggata aaagtttttc caattatatg 23460
gtagattgtt aactccaaga taccagtata cctcaaaaat ttgagtgaga tccgctgcca 23520
agttcctatt attgaagatc gcaataccca attctttgac ctgagttagt gatctccaat 23580
ccatgttagc gcttcctaaa taaatatgtg tattatcaga tatccaaaat tttgtatgaa 23640
gaactcctcc taggatattt gtaatatcta tgtatcgtac ttcaactccg gccatttgta 23700
gtctttcaac atcctttaat ggtttgttag atttattgac ggctactcta actcgtactc 23760
ctcttttggg taattgtaca atctcgttta atattatcgt gccgaaattc gtacccactt 23820
catccgataa actccaataa aaagatgata tatctagtgt ttttgtggta ttggatagaa 23880
tttccctcca catgttaaat gtagacaaat atactttatc aaattgcata cctataggaa 23940
tagtctctgt aatcactgcg attgtattat ccggattcat tttatttgtt aaaagaataa 24000
tcctatatca cttcactcta ttaaaaatcc aagtttctat ttctttcatg actgattttt 24060
taacttcatc cgtttcctta tgaagatgat gtttggcacc ttcataaatt tttatttctc 24120
tattacaatt tgcatgttgc atgaaataat atgcacctaa aacatcgcta atctcattgt 24180
ttgttccctg gagtatgaga gtcggggtgt taatcttgga aattattttt ctaaccttgt 24240
tggtagcctt caagacctga ctagcaaatc cagccttaat tttttcatga ttgattaatg 24300
ggtcgtattg gtatttataa actttatcca tatctctaga tactgattct ggacatagct 24360
ttccgactgg cgcatttggt gtgatggttc ccataagttt ggcagctagc agattcagtc 24420
ttgaaacagc atctgcatta actagaggag acattagaat cattgctgta aacaagtttg 24480
gattatcgta agaggctagt atagaaattg ttgctcccat ggaatgaccc aataagtaga 24540
tttaatagtt accacgtgct gtaccaaagt catcaatcat cattttttca ccattacttc 24600
ttccatgtcc aatatgatca tgtgagaata ctaaaattcc taacgatgat atgttttcag 24660
ctagttcgtc ataacgtcca gaatgtttac cagctccatg acttatgaat actaatgcct 24720
taggatatgt aatcattgtc cagattgaac atacagtttg cactcatgat tcacgttata 24780
taactatcaa tattaacagt tcgtttgatg atcatattat ttttatgttt tattgataat 24840
tgtaaaaaca tacaattaaa tcaatataga ggaaggagac ggctactgtc ttttgtgaga 24900
tagtcatggc gactaaatta gattatgagg atgctgtttt ttactttgtg gatgatgata 24960
aaatatgtag tcgcgactcc atcatcgatc taatagatga atatattacg tggagaaatc 25020
atgttatagt gtttaacaaa gatattacca gttgtggaag actgtacaag gaattgatga 25080
agttcgatga tgtcgctata cggtactatg gtattgataa aattaatgag attgtcgaag 25140
ctatgagcga aggagaccac tacatcaatt ttacaaaagt ccatgatcag gaaagtttat 25200
tcgctaccat aggaatatgt gctaaaatca ctgaacattg gggatacaaa aagatttcag 25260
aatctagatt ccaatcattg ggaaacatta cagatctgat gaccgacgat aatataaaca 25320
tcttgatact ttttctagaa aaaaaattga attgatgata taggggtctt cataacgcat 25380
aattattacg ttagcattct atatccgtgt taaaaaaaat tatcctatca tgtatttgag 25440
agttttatat gtagcaaaca tgatagctgt gatgccaata agctttagat attcacgcgt 25500
gctagtgtta gggatggtat tatctggtgg tgaaatgtcc gttatataat ctacaaaaca 25560
atcatcgcat atagtatgcg atagtagagt aaacattttt atagttttta ctggattcat 25620
acatcgtcta cccaattcgg ttatgaatga aattgtcgcc aatcttacac ccaacccctt 25680
gttatccatt agtatagtat taacttcgtt atttatgtca taaactgtaa atgattttgt 25740
agatgccata tcatacatga tattcatgtc cctattataa tcattactaa ctttatcaca 25800
atatatgttg ataatatcta tatatgatct agtctttgtg ggcaactgtc tatacaagtc 25860
gtctaaacgt tgtttactca tatagtatcg aacagccatc attacatggt cccgttccgt 25920
tgatagataa tcgagtatgt tagtggactt gtcaaatcta tataccatat tttctggaag 25980
tggatataca tagtcgtgat caacattatt gctagcctca tcttctatat cctgtactat 26040
accatctaca taatctacga tattattaca cataaacatc gacaacatac tattgtttat 26100
tatctaagtc ctgttgatcc aaacccttga tctcctctat ttgtactatc tagagattgt 26160
acttcttcca gttctggata atatatacgt tgatagatta gctgagctat tctatctcca 26220
gtatttacat taaacgtaca ttttccatta ttaataagaa tgactcctat gtttccccta 26280
taatcttcgt ctattacacc acctcctata tcaatgcctt ttagtgacag accagaccta 26340
ggagctattc taccatagca aatcttaggc atggacatac taatatctgt cttaattaac 26400
tgtctttctc ctggagggat agtataatcg taagcgctat acaaatcata tccggcagca 26460
cccggcgatt gcctagtagg agatttagct ctgttagttt ccttaacaaa tctaactggt 26520
gagttaatat tcatgttgaa cataaaacta atattttatt tcaaaattat ttaccatccc 26580
atatattcca tgaataagtg tgatgattgt acacttctat agtatctata tacgattcac 26640
gataaaatcc tcctatcaat agcagtttat tatccactat gatcaattct ggattatccc 26700
tcggataaat aggatcatct atcagagtcc atgtattgct ggattcacaa taaaattccg 26760
catttctacc aaccaagaat aaccttctac cgaacactaa cgcgcatgat ttataatgag 26820
gataataagt ggatggtcca aactgccact gatcatgatt gggtagcaaa tattctgtag 26880
ttgtatcagt ttcagaatgt cctcccatta cgtatataac attgtttatg gatgccactg 26940
ctggattaca tctaggtttc agaagactcg gcatattaac ccaagcagca tccccgtgga 27000
accaacgctc aacagatgtg ggatttggta gacctcctac tacgtataat ttattgttag 27060
cgggtatccc gctagcatac agtctggggc tattcatcgg aggaattgga atccaattgt 27120
ttgatatata atttacagct atagcattgt tatgtatttc attgttcatc catccaccga 27180
tgagatatac tacttctcca acatgagtac ttgtacacat atggaatata tctataattt 27240
gatccatgtt cataggatac tctatgaatg gatacttgta tgatttgcgt ggttgtttat 27300
cacaatgaaa tattttggta cagtctagta tccattttac attatttata cctctgggag 27360
aaagataatt tgacctgatt acatttttga taaggagtag cagatttcct aatttatttc 27420
ttcgctttat ataccactta atgacaaaat cctcatctgg aacatttagt tcatcgcttt 27480
ctagaataag tttcatagat agataatcaa aattgtctat gatgtcatct tccagttcca 27540
aaaagtgttt ggcaataaag tttttagtat gacataagag attggatagt ccgtattcta 27600
tacccatcat gtaacactcg acacaatatt cctttctaaa atctcgtagg ataaagttta 27660
tacaagtgta gatgataaat tctacagagg ttaatataga agcacgtaat aaattgacga 27720
cgttatgact atctatatat acctttccag tatatgagta aataactata gaagttagac 27780
tgtgaatgtc aaggtctaga caaaccctcg taactggatc tttatttttc gtgtattttt 27840
gacgtaaatg tgtgcgaaag taaggagata actttttcaa tatcgtagaa ttgactatta 27900
tattgcctcc tatggcatca ataattgttt tgaatttctt agtcatagac aatgctaata 27960
tattcttaca gtacacagta ttgacaaata tcggcattta tgtttcttta aaagtcaaca 28020
tctaaagaaa aatgattatc ttcttgagac ataactccca ttttttggta ttcacccaca 28080
cgtttttcga aaaaattagt tttaccttct aatgatatat tttccatgaa atcaaacgga 28140
ttggtaacat tataaatttt tttaaatccc aattcagaaa tcaatctatc cgcgacgaat 28200
tctatatatg ttttcatcat ttcacaattc attcctataa gtttaactgg aagagccgca 28260
gtaagaaatt cttgttcaat ggataccgca tctgttataa tagatctaac ggtttcttca 28320
ctcggtggat gcaataaatg tttaaacatc aaacatgcga agtcgcagtg tagaccctcg 28380
tctctactaa tcaattcgtt ggaaaacgtg agtccgggca ttaggccacg ctttttaagc 28440
caaaatatgg aagcgaatga tccggaaaag aagattcctt ctactgcagc aaaggcaata 28500
agtctctctc cataaccggc gctgtcatgt atccactttt gagcccaatc ggccttcttt 28560
tttacacaag gcatcgtttc tatggcatta aagagatagt ttttttcatt actatcttta 28620
acataagtat cgatcaaaag actatacatt tccgaatgaa tgttttcaat ggccatctga 28680
aatccgtaga aacatctagc ctcggtaatc tgtacttctg tacaaaatcg ttccgccaaa 28740
ttttcattca ctattccgtc actggctgca aaaaacgcca atacatgttt tataaaatat 28800
ttttcgtctg gtgttagttt attccaatca ttgatatctt tagatatatc tacttcttcc 28860
actgtccaaa atgatgcctc tgccttttta tacatgttcc agatgtcatg atattggatt 28920
gggaaaataa caaatctatt tggatttggt gcaaggatgg gttccataac taaattaaca 28980
ataacaataa attttttttc agttatctat atgcctgtac ttggatcttt tgtacatcga 29040
tatcgccgca atcactacaa taattacaag tattattgat agcattgtta ttagtactat 29100
cataattaaa ttatcgttat tatcattttg taattgtgac atcatactag ataaatcgtt 29160
tgcgagattg ttgtgggaag cgggcatgga ggatgaatta tcgttattat tatttaaagc 29220
ctcccattcg gattcacaaa tatggcgcgc gttcaacatt ttatggaaac agataacaag 29280
aaaactcgtc atcgttcaaa tttttaacga tagtaaaccg attaaacgtc gagctaattt 29340
ctaacgctag cgactctgtt ggatatgggt ttccagatat atatcttttc agttccccta 29400
cgtatctata atcatctgta ggaaatggaa gatatttcca tttatctact gttcctaata 29460
tcatatgtgg tggtgtagta gaaccattaa gcgcgaaaga tgttatttcg catcgtattt 29520
taacttcgca ataatttctg gttagataac gcactctacc agtcaagtca atgatattag 29580
cctttacaga tatattcata gtagtcgtaa cgatgactcc atcttttaga tgcgatactc 29640
ctttgtatgt accagaatct tcgtacctca aactcgatat atttaaacaa gttaatgaga 29700
tattaacgcg ttttatgaat gatgatatat aaccagaagt tttatcctcg gtggctagcg 29760
ctataacctt atcattataa taccaactag tgtgattaat atgtgacacg ttagtgtggg 29820
tacaaatatg tacattatcg tctacgtcgt attcgataca tccgcataca gccaacaaat 29880
ataaaatgac aaatactcta acgccgttcg tacccatctt gatgcggttt aataaatgtt 29940
ttgatttcaa tttattgtaa aaaaagattc ggttttatac tgttcgatat tctcattgct 30000
tatattttca tctatcatct ccacacagtc aaatccgtgg ttagcatgca cctcatcaac 30060
cggtaaaaga ctatcggact cttctatcat tataactcta gaatatttaa tttggtcatt 30120
attaatcaag tcaattatct tatttttaac aaacgtgagt attttactca ttttttataa 30180
aaacttttag aaatatacag actctatcgt gtgtctatat cttcttttta tatccaatgt 30240
atttatgtct gatttttctt catttatcat atataatggt ccaaattcta cacgtgcttc 30300
ggattcatcc agatcattaa ggttcttata attgtaacat ccttctcttc cctcttctac 30360
atcttccttc ttattcttat tcttagcgtc acagaatcta ccacagcagg atcccatgac 30420
gagcgtcata ttaaactaat ccattttcaa ttataatata cgattagtaa tgaccattaa 30480
aataaaaata ttcttcataa ccggcaagaa agtgaaaagt tcacattgaa actatgtcag 30540
tagtatacat catgaaatga tgatatatat atactctatt ttggtggagg attatatgat 30600
ataattcgtg gataatcatt cttaagacac atttcttcat tcgtaaatct tttcacgtta 30660
aatgagtgtc catattttgc aatttcttca tatgatggcg gtgtacgtgg acgaggctgc 30720
tcctgttctt gttgtagtcg ccgactgtcg tgtctgcgtt tagatccctc cattatcgcg 30780
attgcgtaga tggagtacta ttttatacct tgtaattaaa tttttttatt aattaaacgt 30840
ataaaaacgt tccgtatctg tatttaagag ccagatttcg tctaatagaa caaatagcta 30900
cagtaaaaat aactagaata attgctacac ccactagaaa ccacggatcg taatacggca 30960
atcggttttc gataataggt ggaacgtata ttttatttaa ggacttaaca attgtctgta 31020
aaccacaatt tgcttccgcg gatcctgtat taactatctg taaaagcata tgttgaccgg 31080
gcggagccga acattctccg atatccaatt tctgtatatc tataatatta ttaacctccg 31140
catacgcatt acagttcttt tctagcttgg ataccgcact aggtacatcg tctagatcta 31200
ttcctatttc ctcagcgata gctcttctat ccttttccgg aagcaatgaa atcacttcaa 31260
taaatgattc aaccatgagt gtgaaactaa gtcgagaatt actcatgcat ttgttagtta 31320
ttcggagcgc gcaattttta aactgtccta taacctctcc tatatgaata gcacaagtga 31380
cattagtagg gatagaatgt tgagctaatt tttgtaaata actatctata aaaagattat 31440
acaaagtttt aaactcttta gtttccgcca tttatccagt ctgagaaaat gtctctcata 31500
ataaattttt ccaagaaact aattgggtga agaatggaaa cctttaatct atatttatca 31560
cagtctgttt tggtacacat gatgaattct tccaatgccg tactaaattc gatatctttt 31620
tcgatttctg gatatgtttt taataaagta tgaacaaaga aatggaaatc gtaataccag 31680
ttatgtttaa ctttgaaatt gttttttatt ttcttgttaa tgattccagc cacttgggaa 31740
aagtcaaagt cgtttaatgc cgatttaata cgttcattaa aaacaaactt tttatccttt 31800
agatgaatta ttattggttc attggaatca aaaagtaaga tattatcggg tttaagatct 31860
gcgtgtaaaa agttgtcgca gcatggtagt tcgtaaattt taatgtataa cagagccatc 31920
tgtaaaaaga taaactttat gtattgtacc aaagatttaa atcctaattt gatagctagc 31980
tcggtatcta ctttatctgc cgaatacagt gctaggggaa aaattataat atttcctctt 32040
tcgtattcgt agttagttct cttttcatgt tcgaaaaagt gaaacatgcg gttaaaatag 32100
tttataacat taatattact gttaataact gccggataaa agtgggatag taatttcacg 32160
aatttgatac tgtcctttct ctcgttaaac gcctttaaaa aaactttaga agaatatctc 32220
aatgatagtt cctgaccatc catagtttgt atcaataata gcaacatatg aagaacacgt 32280
ttatacagag tatgtaaaaa tgttaattta tagtttaatc ccatggccca cgcacacacg 32340
attaattttt tttcatctcc ctttagattg ttgtatagaa atttgggtac tgtgaactcc 32400
gccgtagttt ccatgggact atataatttt gtggcctcga atacaaattt tactacatag 32460
ttatctatct taaagactat accatatcct cctgtagata tgtgataaaa atcgtcgttt 32520
ataggataaa atcgtttatc cttttgttgg aaaaaggatg aattaatgta atcattctct 32580
tctatcttta gtagtgtttc cttattaaaa ttcttaaaat aatttaacaa tctaactgat 32640
ggagcccaat tttggtgtaa atctaattgg gacattatat tgttaaaata caaacagtct 32700
cctaatataa cagtatctga taatctatgg ggagacatcc attgatattc aggggatgaa 32760
tcattggcaa cacccattta ttgtacaaaa agccccaatt tacaaacgaa agtccaggtt 32820
tgatagagac aaactattaa ctattttgtc tctgttttta atttctttgg taatgaaatt 32880
attcacaata tcagtatctt ctttatctac cagagatttt actaacttga taaccttggc 32940
tgtctcattc aatagggtag taatatttgt atgtgtgata ttgatatctt ttagaagtga 33000
ttctttgatg gtgccagcat acgaattaca ataatgcaga aactcggtta acatgcagga 33060
attatagtaa gccaattcca attgttgcct gtgttgtatt agagtgtcaa tatgagcaat 33120
ggtgtccttg cgtttctctg atagaatgcg agcagcgatt ttggcgttat catttgacga 33180
tatttctgga atgacgaatc ctgtttctac taactttttg gtaggacaaa gtgaaacaat 33240
caagaagata gcttctcctc ctatttgtgg aagaaattga actcctctag atgatctcct 33300
tgacagatat tggaccgaat tacagaagta cctggaatgt aaagccctga aaccccctca 33360
ttttttaagc agattgttgc cgtaaatcct gcactatgcc caagatagag agctcctttg 33420
gtgaatccat ctctatgttt cagtttaacc aagaaacagt cagctggtct aaaatttcca 33480
tctctatcta atacagcatc taacttgatg tcaggaacta tgaccggtta tgttatatgt 33540
aacattgagt aaatccttaa gttcataatc atcactgtca tcagttatgt acgatccaaa 33600
caatgtttct actggcatag tggatacgaa gatgctatcc atcagaatgt ttccctgatt 33660
agtattttct atatagctat tcttctttaa acgattttcc aaatcagtaa ctatgttcat 33720
ttttttagga gtaggacgcc tagccagtat ggaagaggat tttctagatc ctctcttcaa 33780
catctttgat ctcaatggaa tgcaaaaccc catagtgtaa caaccaacga taaaaataat 33840
attgtttttc actttttata attttaccat ctgactcatg gattcattaa tatctttata 33900
agagctacta acgtataatt ctttataact gaactgagat atatacaccg gatctatggt 33960
ttccataatt gagtaaatga atgctcggca ataactaatg gcaaatgtat aaaacaacga 34020
aattatacta gagttgttaa agttaatatt ttctatgagc tgttccaata aattatttgt 34080
tgtaactgcg ttcaagtcat aaatcatctt gatactatcc agtaaaccgt ttttaagttc 34140
tggaatatta ttatcccatt gtaaagcccc taattcgact atcgaatatc ctgctctgat 34200
agcagtttca atatcgacgg acgtcaatac tgtaataaag gtggtagtat tgtcatcatc 34260
gtgataaact actggaatat ggtcgttagt aggtacggta actttacaca acgcgatata 34320
taactttcct tttgtaccat ttttaacgta gttgggacgt cctgcagggt attgttttga 34380
agaaatgata tcgagaacag atttgatacg atatttgttg gattcctgat tatttactat 34440
aatataatct agacagatag atgattcgat aaatagagaa ggtatatcgt tggtaggata 34500
atacatcccc attccagtat tctcggatac tctattaatg acactagtta agaacatgtc 34560
ttctattcta gaaaacgaaa acatcctaca tggactcatt aaaacttcta acgctcctga 34620
ttgtgtctcg aatgcctcgt acaaggattt caaggatgcc atagattctt tgaccaacga 34680
tttagaattg cgtttagcat ctgatttttt tattaaatcg aatggtcggc tctctggttt 34740
gctaccccaa tgataacaat agtcttgtaa agataaaccg caagaaaatt tatacgcatc 34800
catccaaata accctagcac catcggatga tattaatgta ttattataga ttttccatcc 34860
acagttattg ggccagtata ctgttagcaa cggtatatcg aatagattac tcatgtaacc 34920
tactagaatg atagttcgtg tactagtcat aatatcttta atccaatcta agaaatttaa 34980
aattagattt tttacactgt taaagttaac aaaggtatta cccggatacg tggatatcat 35040
atatggtatt ggtccattat cagtaatagc tccataaact gatacggcga tggtttttat 35100
atgtgtttga tctaacgagg aagaaattcg cgcccacaat tcatctctag atatgtattt 35160
aatatcaaac ggtaacacat caatttcggg acgcgtatat gtttctaaat ttttaatcca 35220
aatataatga tgacctatat gccctattat catactgtca actatagtac acctagagaa 35280
cttacgatac atctgtttcc tataatcgtt aaattttaca aatctataac atgctaaacc 35340
ttttgacgac aaccattcat taatttctga tatggaatct gtattctcaa taccgtatcg 35400
ttctaaagcc agtgctatat ctccctgttc gtgagaacgc tttcgtataa tatcgatcaa 35460
cggataatct gaagtttttg gagaataata tgactcatga tctatttcgt ccataaacaa 35520
tctagacata ggaattggag gcgatgatct taattttgtg caatgagtcg tcaatcctat 35580
aacttctaat attgtaatat tcatcatcga cataacacta tctatgttat catcgtatat 35640
tagtatacca tgaccttctt catttcgtgc caaaatgata tacagtctta aatagttacg 35700
caatatctca atagtttcat aattgttagc tgttttcatc aaggtttgta tcctgtttaa 35760
catgatggcg ttctatacgt ttctattttt taaattttta acgatttact gtggctagat 35820
acccaatctc tctcaaatat ttttttagcc tcgcttacaa gctgtttatc tatactatta 35880
aaactgacga atccgtgatt ttggtaatgg gttccgtcga aatttgccga agtgatatga 35940
acatattcgt cgtcgactat caacaatttt gtattattct gaatagtgaa aaccttcaca 36000
gatagatcat tttgaacaca caacgcgtct agacttctgg cggttgccat agaatatacg 36060
tcgttcttat cccaattacc aactagaagt ctgatcttaa ctcctctatt aatggctgct 36120
tctataatgg agttgtaaat gtcgggccaa tagtagctat taccgtcgac acgtgtagtg 36180
ggaactatgg ccaaatgttc aatatctata ctagtcttag ccgacttgag tttatcaata 36240
actacatcag tgtctagatc tctagaatat cccaataggt gttccggaga atcagtaaag 36300
aacactccac ctataggatt cttaatatga tacgcagtgc taactggcag acaacaagcc 36360
gcagagcata aattcaacca tgaatttttt gcgctattaa aggctttaaa agtatcaaat 36420
cttctacgaa gatctgtggc cagcggggga taatcagaat atacacctaa cgttttaatc 36480
gtatgtatag atcctccagt aaatgacgcg tttcctacat aacatctttc attatctgac 36540
acccaaaaac aaccgagtag tagtcccaca ttattttttt tatctatatt aacggttata 36600
aaatttatat ccgggcagtg actttgtagc tctcccagat ttcttttccc tcgttcatct 36660
agcaaaacta ttattttaat ccctttttca gatgcctctt ttagtttatc aaaaataagc 36720
gctcccctag tcgtactcag aggattacaa caaaaagatg ctatgtatat atatttctta 36780
gctagagtga taatttcgtt aaaacattca aatgttgtta aatgatcgga tctaaaatcc 36840
atattttctg gtagtgtttc taccagccta cattttgctc ccgcaggtac cggtgcaaat 36900
ggccacattt agttaacata aaaacttata catcctgttc tatcaacgat tctagaatat 36960
catcggctat atcgctaaaa ttttcatcaa agtcgacatc acaacctaac tcagtcaata 37020
tattaagaag ttccatgatg tcatcttcgt ctatttctat atccgtatcc attgtagatt 37080
gttgaccgat tatcgagttt aaatcattac taatactcaa tccttcagaa tacaatctgt 37140
gtttcattgt aaatttatag gcggtgtatt taagttggta gattttcaat tatgtatcaa 37200
tatagcaaca gtagttcttg ctcctccttg attctagcat cctcttcatt attttcttct 37260
acgtacataa acatgtccaa tacgttagac aacacaccga cgatggcggc cgccacagac 37320
acgaatatga ctaaaccgat gaccatttaa aaacccctct ctagctttca cttaaactgt 37380
atcgattatt cttttagaac atgtataata taaaaacatt attctatttc gaatttaggc 37440
ttccaaaaat ttttcatccg taaaccgata ataatatata tagacttgtt aatagtcgga 37500
ataaatagat taatgcttaa actatcatca tctccacgat tagagataca atatttacat 37560
tttttttgct gtttcgaaac tttatcaata cacgttaata caaacccagg aaggagatat 37620
tgaaactgag gctgttgaaa atgaaacggt gaatacaata attcagataa tgtaaaatca 37680
tgattccgta ttctgatgat attagaactg ctaatggatg tcgatggtat gtatctagga 37740
gtatctattt taacaaagca tcgatttgct aatatacaat tatcattttg attaattgtt 37800
attttattca tattcttaaa aggtttcata tttatcaatt cttctacatt aaaaatttcc 37860
atttttaatt tatgtagccc cgcaatactc ctcattacgt ttcatttttt gtctataata 37920
tccattttgt tcatctcggt acatagatta tccaattgag aagcgcattt agtagttttg 37980
tacattttaa gtttattgac gaatcgtcga aaactagtta tagttaacat tttattattt 38040
gataccctga tattaatacc cctgccgtta ctattattta taactgatgt aatccacgta 38100
acattggaat taactatcga tagtaatgca tcgacgcttc caaaattgtc tattataaac 38160
tcaccgataa tttttttatt acatgttttc atattcatta ggattattaa atctttaatc 38220
ttactacgat tgtatgcgtt gatattgcaa gacgtcattc taaaagacgg aggatctcca 38280
tcaaatgcca gacaatcacg tacaaagtac atggaaatag gttttgttct attgcgcatc 38340
atagatttat atagaacacc cgtagaaata ctaatttgtt ttactctata aaatactaat 38400
gcatctattt catcgttttg tataacgtct ttccaagtgt caaattccaa atttttttca 38460
ttgatagtac caaattcttc tatctcttta actacttgca tagataggta attacagtga 38520
tgcctacatg ccgttttttg aaactgaata gatgcgtcta gaagcgatgc tacgctagtc 38580
acaatcacca ctttcatatt tagaatatat atatgtaaaa atatagtaga atttcatttt 38640
gttttttttc tatgctataa atgaattctc attttgcatc tgctcatact ccgttttata 38700
tcaataccaa agaaggaaga tatctggttc taaaagccgt taaagtatgc gatgttagaa 38760
ctgtagaatg cgaaggaagt aaagcttcct gcgtactcaa agtagataaa ccctcatcac 38820
ccgcgtgtga gagaagacct tcgtcccctt ccagatgcga gagaatgaat aacccaggaa 38880
aacaagttcc gtttatgagg acggacatgc tacaaaatat gttcgcggct aatcgcgata 38940
atgtagcttc tagacttttg tcctaaaata caattatatc cttttcgata ttaataaatc 39000
cgtgtcgtcc aggtttttta tctctttcag tatgtgaata gataggtatt ttatctctat 39060
tcatcatcga atttaagaga tccgataaac attgtttgta ttctccagat gtcagcatct 39120
gatacaacaa tatatgtgca cataaacctc tggcacttat ttcatgtacc ttccccttat 39180
cactaaggag aatagtattt gagaaatatg tatacatgat attatcatga attagatata 39240
cagaatttgt aacactctcg aaatcacacg atgtgtcggc gttaagatct aatatatcac 39300
tcgataacac attttcatct agatacacta gacatttttt aaagctaaaa tagtctttag 39360
tagtaacagt aactatgcga ttattttcat cgatgataca tttcatcggc atattattac 39420
gcttaccatc aaagactata ccatgtgtat atctaacgta ttctagcatg gttgccatac 39480
gcgcattaaa cttttcagga tctttggata gatcttccaa tctatctatt tgagaaaaca 39540
tttttatcat gttcaatagt tgaaacgtcg gatccactat atagatatta tctataaaga 39600
ttttaggaac tacgttcatg gtatcctggc gaatattaaa actatcaatg atatgattat 39660
cgttttcatc ttttatcacc atatagtttc taagatatgg gattttactt aatataatat 39720
tatttcccgt aataaatttt attagaaatg ccaaatctat aagaaaagtc ctcgaattag 39780
tttgaagaat atctatatcg ccgtaccgta tatttggatt aattagatat agagaatatg 39840
atccgtaaca tatacaactt ttattatggc gtctaagata ttcttccatc aacttattaa 39900
catttttgac tagggaagat acattatgac gtcccattac ttttgccttg tctattactg 39960
cgacgttcat agaatttagc atatctcttg ccaattcttc cattgatgtt acattataag 40020
aaattttaga tgaaattaca tttggagctt taatagtaag aactcctaat atgtccgtgt 40080
atgtggtcac taatacagat tgtagttcta taatcgtaaa taatttacct atattatatg 40140
tttgagtctg tttagaaaag tagctaagta tacgatcttt tatttctgat gcagatgtat 40200
caacatcgga aaaaaatctt tttttattct tttttactaa agatacaaat atgtctttgt 40260
taaaaacagt tattttctga atatttctag cttgtaattt taacatatga tattcgttca 40320
cactaggtac tctgcctaaa taggtttcta taatctttaa tgtaatatta ggaaaagtat 40380
tctgatcagg attcctattc attttgagga tttaaaactc tgattattgt ctaatatggt 40440
ctcaacacaa actttttcac agagcgatag agtttttgat aactcgtttt tcttaagaaa 40500
tataaaacta ctgtctccag agctcgctct atcttttatt ttatttaatt cgatacaaac 40560
tcctgatact ggttcagaaa gtaattcatt aattttcagt cctttataga agatatttaa 40620
tatagataat acaaaatctt cagtttttga tatcgatctg attgatccta gaactagata 40680
tattaataac gtgctcatta ggcagtttat ggcagcttga taattagata tagtatattc 40740
cagttcatat ttattagata ccgcattgcc cagattttga tattctatga attcctctga 40800
aaataaatcc aaaataacta gacattctat tttttgtgga ttagtgtact ctcttccctc 40860
tatcatgttc actactggtg tccacgatga taaatatcta gagggaatat aatatagtcc 40920
ataggatgcc aatctagcaa tgtcgaataa ctgtaatttt attcttcgct cttcattatg 40980
aattgattct tgaggtataa acctaacaca aattatatta ttagactttt cgtatgtaat 41040
gtctttcatg ttataagttt ttaatcctgg aatagaatct attttaatga ggcttttaaa 41100
cgcagagttc tccaacgagt caaagcataa tactctgttg gttttcttat atacgatgtt 41160
acgattttct tctttgaatg gaataggttt ttgaattagt ttataattac aacataatag 41220
ataaggaagt gtgcaaatag tacgcggaaa aaacataata gctcccctgt tttcatccat 41280
ggttttaagt aaatgatcac tggcttcttt agtcaatgga tattcgaaca ttaaccgttt 41340
catcatcatt ggacagaatc catatttctt aatgtaaaga gtgatcaaat cattgtgttt 41400
attgtaccat cttgttgtaa atgtgtattc ggttatcgga tctgctcctt tttctattaa 41460
agtatcgatg tcgatctcgt ctaagaattc aactatatcg acatatttca tttgtataca 41520
cataaccatt actaacgtag aatgtatagg aagagatgta acgggaacag ggtttgttga 41580
ttcgcaaact attctaatac ataattcttc tgttaatacg tcttgcacgt aatctattat 41640
agatgccaag atatctatat aattattttg taagatgatg ttaactatgt gatctatata 41700
agtagtgtaa taattcatgt atttcgatat atgttccaac tctgtctttg tgatgtctag 41760
tttcgtaata tctatagcat cctcaaaaaa tatattcgca tatattccca agtcttcagt 41820
tctatcttct aaaaaatctt caacgtatgg aatataataa tctattttac ctcttctgat 41880
atcattaatg atatagtttt tgacactatc ttctgtcaat tgattcttat tcactatatc 41940
taagaaacgg atagcgtccc taggacgaac tactgccatt aatatctcta ttatagcttc 42000
tggacataat tcatctatta taccagaatt aatgggaact attccgtatc tatctaacat 42060
agttttaaga aagtcagaat ctaagacctg atgttcatat attggttcat acatgaaatg 42120
atctctattg atgatagtga ctatttcatt ctctgaaaat tggtaactca ttctatatat 42180
gctttccttg ttgatgaagg atagaatata ctcaatagaa tttgtaccaa caaactgttc 42240
tcttatgaat cgtatatcat catctgaaat aatcatgtaa ggcatacatt taacaattag 42300
agacttgtct cctgttatca atatactatt cttgtgataa tttatgtgtg aggcaaattt 42360
gtccacgttc tttaattttg ttatagtaga tatcaaatcc aatggagcta cagttcttgg 42420
cttaaacaga tatagttttt ctggaacgaa ttctacaaca ttattataaa ggactttggg 42480
tagataagtg ggatgaaatc ctattttaat taatgcgata gccttgtcct cgtgcagata 42540
tccaaacgct tttgtgatag tatggcattc attgtctaga aacgctctac gaatatctgt 42600
gacagatatc atctttagag aatatactag tcgcgttaat agtactacaa tttgtatttt 42660
ttaatctatc tcaataaaaa aattaatatg tatgattcaa tgtataacta aactactaac 42720
tgttattgat aactagaatc agaatctaat gatgacgtaa ccaagaagtt tatctactgc 42780
caatttagct gcattatttt tagcatctcg tttagatttt ccatctgcct tatcgaatac 42840
tcttccgtcg atatctacac aggcataaaa tgtaggagag ttactaggcc ccactgattc 42900
aatacgaaaa gaccaatctc tcttagttat ttggcagtac tcattaataa tggtgacagg 42960
gttagcatct ttccaatcaa taattttttt agccggaata acatcatcaa aagacttatg 43020
atcctctctc attgattttt cgcgggatac atcatctatt atggcgtcag ccataacatc 43080
agcatccggc ttatccgcct ccgttgtcat aaaccaacga ggaggaatat cgtcggagct 43140
gtacaccata gcactacgtt gaagatcgta cagagcttta ttaacttctc gcttctccat 43200
attaagttgt ctagttagtt gtgcagcagt agctccttcg attccaatgt ttttaatagc 43260
cgcacacaca atctctgcgt cagaacgctc gtcaatatag atcttagaca tttttagaga 43320
gaactaacac aaccagcaat aaaactaatt tattttatca tttttttatt catcatcctc 43380
tggtggttcg tcgtttctat cgaatgtgga tctgattaac ccgtcatcta taggtgatgc 43440
tggttctgga gattctggag gagatggatt attatctgga agaatctctg ttatttcctt 43500
gttttcatgt atcgattgcg ttgtaacatt aagattgcga aatgctctaa atttgggagg 43560
cttaaagtgt tgtttgcaat ctctacacgc atgtctaact agtggaggtt cgtcagcggc 43620
tctagtttga atcatcatcg gcgtagtatt cctactttta cagttaggac acggtgtatt 43680
gtatttctcg tcgagaacgt taaaataatc gttgtaactc acatccttta ttttatctat 43740
attgtattct actcctttct taatgcattt tataccgaat aagagatagc gaaggaattc 43800
tttttcggtg ccgctagtac ccttaatcat atcacatagt gttttatatt ccaaatttgt 43860
ggcaatagac ggtttatttc tatacgatag tttgtttctg gaatcctttg agtattctat 43920
accaatatta ttctttgatt cgaatttagt ttcttcgata ttagattttg tattacctat 43980
attcttgatg tagtactttg atgatttttc catggcccat tctattaagt cttccaagtt 44040
ggcatcatcc acatattgtg atagtaattc tcggatatca gtagcggcta ccgccattga 44100
tgtttgttca ttggatgagt aactactaat gtatacattt tccatttata acacttatgt 44160
attaactttg ttcatttata ttttttcatt attatgttga tattaacaaa agtgaatata 44220
tatgttaata attgtattgt ggttatacgg ctacaatttc ataatgagtg gaagtcagtg 44280
tccgatgatc aatgacgata gctttactct gaaaagaaag tatcaaatcg atagtgcgga 44340
gtcaacaata aaaatggata agaagaggat aaagtttcag aatagagcca aaatggtaaa 44400
agaaataaat cagacaataa gagcagcaca aactcattac gagacattga aactaggata 44460
cataaaattt aagagaatga ttaggactac tactctagaa gatatagcac catctattcc 44520
aaataatcag aaaacttata aactattctc ggacatttca gccatcggca aagcatcaca 44580
gaatccgagt aagatggtat atgctctgct gctttacatg tttcccaatt tgtttggaga 44640
tgatcataga ttcattcgtt atagaatgca tccaatgagt aaaatcaaac acaagatctt 44700
ctctcctttc aaacttaatc ttattagaat attagtggaa gaaagattct ataataatga 44760
atgcagatct aataaatgga gaataattgg aacacaagtt gataaaatgt tgatagctga 44820
atctgataaa tatacaatag atgcaaggta taacctaaaa cccatgtata gaatcaaggg 44880
aaaatctgaa gaagataccc tctttatcaa acagatggta gaacaatgtg tgacatccca 44940
ggaattggtg gaaaaagtgt tgaagatact gtttagagat ttgttcaaga gtggagaata 45000
caaagcgtac agatacgatg atgatgtaga aaatggattt attggattgg atacactaaa 45060
attaaacatt gttcatgata tagttgaacc atgtatgcct gttcgtaggc cagtggctaa 45120
gatactgtgt aaagaaatgg taaataaata ctttgagaat ccgctacata ttattggtaa 45180
aaatcttcaa gagtgcattg actttgttag tgaataggca tttcatcttt ctccaatact 45240
aattcaaatt gttaaattaa taatggatag tataaatagt tattagtgat aaaatagtaa 45300
aaataattat tagaataaga gtgtagtatc atagataact ctcttctata aaaatggatt 45360
ttattcgtag aaagtatctt atatacacag tagaaaataa tatagatttt ttaaaggatg 45420
atacattaag taaagtaaac aattttaccc tcaatcatgt actagctctc aagtatctag 45480
ttagcaattt tcctcaacac gttattacta aggatgtatt agctaatacc aatttttttg 45540
ttttcataca tatggtacga tgttgtaaag tgtacgaagc ggttttacga cacgcatttg 45600
atgcacccac gttgtacgtt aaagcattga ctaagaatta tttatcgttt agtaacgcaa 45660
tacaatcgta caaggaaacc gtgcataaac taacacaaga tgaaaaattt ttagaggttg 45720
ccgaatacat ggacgaatta ggagaactta taggcgtaaa ttatgactta gttcttaatc 45780
cattatttca cggaggggaa cccatcaaag atatggaaat cattttttta aaactgttta 45840
agaaaacaga cttcaaagtt gttaaaaaat taagtgttat aagattactt atttgggctt 45900
acctaagcaa gaaagataca ggcatagagt ttgcggataa tgatagacaa gatatataca 45960
ctctatttca acaaactggt agaatagtcc atagcaatct aacagaaacg tttagagatt 46020
atatctttcc cggagataag actagctatt gggtgtggtt aaacgaaagt atagctaatg 46080
atgcggatat tgttcttaat agacacgcca ttaccatgta tgataaaatt cttagttata 46140
tatactctga gataaaacaa ggacgcgtta ataaaaacat gcttaagtta gtttatatct 46200
ttgagcctga aaaagatatc agagaacttc tgctagaaat catatatgat attcctggag 46260
atatcctatc tattattgat gcaaaaaacg acgattggaa aaaatatttt attagttttt 46320
ataaagctaa ttttattaac ggtaatacat ttattagtga tagaacgttt aacgaggact 46380
tattcagagt tgttgttcaa atagatcccg aatatttcga taatgaacga attatgtctt 46440
tattctctac gagtgctgcg gacattaaac gatttgatga gttagatatt aataacagtt 46500
atatatctaa tataatttat gaggtgaacg atatcacatt agatacaatg gatgatatga 46560
agaagtgtca aatctttaac gaggatacgt cgtattatgt taaggaatac aatacatacc 46620
tgtttttgca cgagtcggat cccatggtca tagagaacgg aatactaaag aaactgtcat 46680
ctataaaatc caagagtaga cggctgaact tgtttagcaa aaacatttta aaatattatt 46740
tagacggaca attggctcgt ctaggtcttg tgttagatga ttataaagga gacttgttag 46800
ttaaaatgat aaaccatctt aagtctgtgg aggatgtatc cgcattcgtt cgattttcta 46860
cagataaaaa ccctagtatt cttccatcgc taatcaaaac tattttagct agttataata 46920
tttccatcat cgtcttattt caaaggtttt tgagagataa tctatatcat gtagaagaat 46980
tcttggataa aagcatccat ctaaccaaga cggataagaa atatatactt caattgataa 47040
gacacggtag atcatagaac agaccaaata tattattaat aatttgtata tacatagata 47100
taattatcac acatttttga taaatgggaa ctgctgcaac aattcagact cccaccaaat 47160
taatgaataa agaaaatgca gaaatgattt tggaaaaaat tgttgatcat atagttatgt 47220
atattagtga cgaatcaagt gattcagaaa ataatcctga atatattgat tttcgtaaca 47280
gatacgaaga ctatagatct ctcattataa aaagtgatca cgagtttgta aagctatgta 47340
aaaatcatgc agagaaaagt tctccagaaa cgcaacaaat gattatcaaa cacatatacg 47400
aacaatatct tattccagta tctgaagtac tattaaaacc tataatgtcc atgggtgaca 47460
taattacata taacggatgt aaagacaatg aatggatgct agaacaactc tctaccctaa 47520
actttaacaa tctccgcaca tggaactcat gtagcatagg caatgtaacg cgtctgtttt 47580
atacattttt tagttatctg atgaaagata aactaaatat ataagtataa tcccattcta 47640
atactttaac ctgatgtatt acctgcatct tattagaata ttaacctaac taaaagacat 47700
aacatagttg ataaaaagcg gtaggatata aatattatgg ctgccaccgt tccgcgtttt 47760
gacgacgtgt acaaaaatgc acaaagaaga attctagatc aagaaacatt ttttagtaga 47820
ggtctaagta gaccgttaat gaaaaacaca tatctatttg ataattacgc gtatggatgg 47880
ataccagaaa ctgcaatttg gagtagtaga tacgcaaact tagatgcaag tgactattat 47940
cccatttcgt tgggattact taaaaagttc gagtttctca tgtctctata taaaggtcct 48000
attcccgtat atgaagaaaa agtaaatact gaattcattg ctaatggatc gttctctggt 48060
agatacgtat catatcttcg aaagttttct gcccttccaa caaacgagtt tattagtttt 48120
ttgttactga cttccattcc aatctataat atcttgttct ggtttaaaaa tactcagttt 48180
gatattacta aacacacatt attcagatac gtctatacag ataatgccaa acacctggcg 48240
ttggctaggt atatgcatca aacaggagac tataagcctt tgtttagtcg tctcaaagag 48300
aattatatat ttaccggtcc cgttccaata agtatcaaag atatagatca ccctaatctt 48360
agtagagcaa gaagtccatc cgattatgag acattagcta atattagtac tatattgtac 48420
tttaccaagt atgatccggt attaatgttt ttattgtttt acgtacctgg gtattcaatt 48480
actacaaaaa ttactccagc cgtagaatat ctaatggata aactgaatct aacaaagagc 48540
gacgtacaac tgttgtaaat tattttatgc ttcgtaaaat gtaggttttg aaccaaacat 48600
tctttcaaag aatgagatgc ataaaacttt attatccaat agattgacta tttcggacgt 48660
caatcgttta aagtaaactt cgtaaaatat tctttgatca ctgccgagtt taaaacttct 48720
atcgataatt gtttcatatg ttttaatatt tacaagtttt ttggtccatg gtacattagc 48780
cggacaaata tatgcaaaat aatatcgttc tccaagttct atagtttctg gattattttt 48840
attatattca gtaaccaaat acatattagg gttatctgcg gatttataat ttgagtgatg 48900
cattcgactc aacataaata attctagagg agacgatcta ctatcaaatt cggatcgtaa 48960
atctgtttct aaagaacgga gaatatctat acatacctga ttagaattca tccgtccttc 49020
agacaacatc tcagacagtc tggtcttgta tgtcttaatc atattcttat gaaacttgga 49080
aacatctctt ctagtttcac tagtaccttt attaattctc tcaggtacag attttgaatt 49140
cgacgatgct gagtatttca tcgttgtata tttcttcttc gattgcataa tcagattctt 49200
atataccgcc tcaaactcta ttttaaaatt attaaacaat actctattat taatcagtcg 49260
ttctaactct ttcgctattt ctatagactt atcgacatct tgactgtcta tctctgtaaa 49320
cacggagtcg gtatctccat acacgctacg aaaacgaaat ctgtaatcta taggcaacga 49380
tgttttcaca atcggattaa tatctctatc gtccatataa aatggattac ttaatggatt 49440
ggcaaaccgt aacataccgt tagataactc tgctccattt agtaccgatt ctagatacaa 49500
gatcattcta cgtcctatgg atgtgcaact cttagccgaa gcgtatgagt atagagcact 49560
atttctaaat cccatcagac catatactga gttggctact atcttgtacg tatattgcat 49620
ggaatcatag atggcctttt cagttgaact ggtagcctgt tttagcatct ttttatatct 49680
ggctctctct gccaaaaatg ttcttaatag tctaggaatg gttccttcta tcgatctatc 49740
gaaaattgct atttcagaga tgaggttcgg tagtctaggt tcacaatgaa ccgtaatata 49800
tctaggaggt ggatatttct gaagcaagag ctgattattt atttcttctt ccaatctatt 49860
ggtactaaca acgacaccga ctaatgtttc cggagataga tttccaaaga tacacacatt 49920
aggatacaga ctgttataat caaagattaa tacattatta ctaaacattt tttgttttgg 49980
agcaaatacc ttaccgcctt cataaggaaa cttttgtttt gtttctgatc taactaagat 50040
agttttagtt tccaacaata gctttaacag tggacccttg atgactgtac tcgctctata 50100
ttcgaatacc atggattgag gaagcacata tgttgacgca cccgcgtctg tttttgtttc 50160
tactccataa tactcccaca aatactgaca caaacaagca tcatgaatac agtatctagc 50220
catatctaaa gctatgttta gattataatc cttatacatc tgagctaaat caacgtcatc 50280
ctttccgaaa gataatttat atgtatcatt aggtaaagta ggacatgata gtacgacttt 50340
aaatccattt tcccaaatat ctttacgaat tactttacat ataatatcct catcaacagt 50400
cacataatta cctgtggtta aaacctttgc aaatgcagcg gctttgcctt tcgcgtccgt 50460
agtatcgtca ccgatgaacg tcatttctct aactcctcta tttaatactt tacccatgca 50520
actgaacgcg ttcttggata tagaatccaa tttgtacgaa tccaattttt cagatttttg 50580
aatgaatgaa tatagatcga aaaatatagt tccattattg ttattaacgt gaaacgtagt 50640
attggccatg ccgcctactc ccttatgact agactgattt ctctcataaa tacagagatg 50700
tacagcttcc tttttgtccg gagatctaaa gataatcttc tctcctgtta ataactctag 50760
acgattagta atatatctca gatcaaagtt atgtccgtta aaggtaacga cgtagtcgaa 50820
cgttagttcc aacaattgtt tagctattcg taacaaaact atttcagaac atagaactag 50880
ttctcgttcg taatccattt ccattagtga ctgtatcctc aaacatcctc tatcgacggc 50940
ttcttgtatt tcctgttccg ttaacatctc ttcattaatg agcgtaaaca ataatcgttt 51000
accacttaaa tcgatataac agtaacttgt atgcgagatt gggttaataa atacagaagg 51060
aaacttctta tcgaagtgac actctatatc tagaaataag tacgatcttg ggatatcgaa 51120
tctaggtatt tttttagcga aacagttacg tggatcgtca caatgataac atccattgtt 51180
aatctttgtc aaatattgct cgtccaacga gtaacatccg tctggagata tcccgttaga 51240
aatataaaac caactaatat tgagaaattc atccatggtg gcattttgta tgctgcgttt 51300
ctttggctct tctatcaacc acatatctgc gacggagcat tttctatctt taatatctag 51360
attataactt attgtctcgt caatgtctat agttctcatc tttcccaacg gcctcgcatt 51420
aaatggagga ggagacaatg actgatatat ttcgtccgta actacgtaat aaaagtaatg 51480
aggaaatcgt ataaatacgg tctcgccatt tcgacatctg gatttcagat ataaaaatct 51540
gttttcaccg tgactttcaa accaattaat gcaccgaaca tccatttata gaatttagaa 51600
atatattttc atttaaatga atcccaaaca ttggggaaga gccgtatgga ccattatttt 51660
tatagtactt tcgcaagcgg gtttagacgg caacatagaa gcgtgtaaac gaaaactata 51720
tactatagtc agcactcttc catgtcctgc atgtagacgg cacgcgacta tcgctataga 51780
ggacaataat gtcatgtcta gcgatgatct gaattatatt tattattttt tcatcagatt 51840
atttaacaat ttggcatctg atcccaaata cgcgatcgat gtgacaaagg ttaacccttt 51900
ataaacttaa cccattataa aacttatgat tagtcacgac tgaaataacc gcgtgattat 51960
tttttggtat aattctacac ggcatggttt ctgtaactat gaattcaacc cccgttacat 52020
tagtgaaatc tttaacaaac agcaagggtt cgtcaaagac ataaaactca ttgtttacaa 52080
tcgaaataga ccccctatca cacttaaaat aaaaaatatc cttatccttt accaccaaat 52140
aaaattctga ttggtcaatg tgaatgtatt cacttaacag ttccacaaat ttatttatta 52200
actccgaggc acatacatcg tcggtatttt ttatggcaaa ctttactctt ccagcatccg 52260
tttctaaaaa aatattaacg agttccattt atatcatcca atattattga aatgacgttg 52320
atggacagat gatacaaata agaaggtacg gtacctttgt ccaccatctc ctccaattca 52380
tgctctattt tgtcattaac tttaatgtat gaaaacagta cgccacatgc ttccatgaca 52440
gtgtgtaaca ctttggatac aaaatgtttg acattagtat aattgtccaa gactgtcaat 52500
ctataataga tagtagctat aatatattct atgatggtat tgaagaagat gacaatcttg 52560
gcatattgat catttaacac agacatggta tcaacagata gcttgaatga aagagaatca 52620
gtaattggaa taagcgtctt ctcgatagag tgtccgtata ccaacatgtc tgatattttg 52680
atgtattcca ttaaattatt tagttttttc tttttattct cgttaaacag catttctgtc 52740
aacggacccc aacatcgttg accgattaag ttttgattga tttttccgtg taaggcgtat 52800
ctagtcagat cgtatagcct atccaataat ccatcatctg tgcgtagatc acatcgtaca 52860
ctttttaatt ctctatagaa gagcgacaga cagcaatttc tttattctct acagatgtaa 52920
gatacttgaa gacattccta tgatgatgca gaattttgga taacacggta ttgatggtat 52980
ctgttaccat aattcctttg atggctgata gtgtcagagc acaagatttc caatctttgt 53040
tttgatatct atatcagaca gcatggtgcg tctgacaaca caaggattaa gacggaaaga 53100
tgaaatgatt ctctcaacat cttcaatgga taccttgcta ttttttctgg cattatctat 53160
atgtgcgaga atatcctcta gagaatcagt atcctttttg atgatagtgg atctcaatga 53220
catgggacgt ctaaaccttc ttattctatc accagattgc atggtgattt gtcttctttc 53280
ttttatcata atgtaatctc taaattcatc ggcaaattgt ctatatctaa aatcataata 53340
tgagatgttt acctctacaa atatctgttc gtccaatgtt agagtatcta catcagtttt 53400
gtattccaaa ttaaacatgg caacggattt aattttatat tcctctatta agtcctcgtc 53460
gataataaca gaatgtagat aatcatttaa tccatcgtac atggttggaa gatgcttgtt 53520
gacaaaatct ttaattgtct tgatgaaggt gggactatat ctaacatctt gattaataaa 53580
atttataaca ttgtccatag gatactttgt aactagtttt atacacatct cttcatcggt 53640
aagtttagac agaatatcgt gaacaggtgg tatattatat tcatcagata tacgaagaac 53700
aatgtccaaa tctatattgt ttaatatatt atatagatgt agcgtagctc ctacaggaat 53760
atctttaact aagtcaatga tttcatcaac cgttagatct attttaaagt taatcatata 53820
ggcattgatt tttaaaaggt atgtagcctt gactacattc tcattaatta accattccaa 53880
gtcactgtgt gtaagaagat tatattctat cataagcttg actacatttg gtcccgatac 53940
cattaaagaa ttcttatgat ataaggaaac agattttagg tactcatcta ctctacaaga 54000
attttggaga gccttaacga tatcagtgac gtttattatt tcaggaggaa agaatctaac 54060
attgagaata tcggaattaa tagcttccag atacagtgat tttggcaata gtccgtgtaa 54120
tccataatcc agtaacacga gctggtgctt gctagacacc ttttcaatgt ttaatttttt 54180
tgaaataagc tttgataaag ccttcctcgc aaattccgga tacatgaaca tgtcggcgac 54240
atgattaagt attgtttttt cattattttc tcaacaagtt ctcaataccc caatagatga 54300
tagaatatca cccaatgcgt ccatgttgtc tatttccaac aggtcgctat atccaccaat 54360
agaagttttt ccaaaaaaga ttctaggaac agttctacca ccagtaattt gttcaaaata 54420
gtcacgcaat tcattttcgg gtttaaattc tttaatatcg acaatttcat acgctcctct 54480
tttgaaacta aacttattta gaatatccag tgcatttcta caaaaaggac atgtatactt 54540
gacaaaaatt gtcactttgt tattggccaa cctttgttgt acaaattcct cggccatttt 54600
aatatttaag tgatataaaa ctatctcgac ttatttaact ctttagtcga gatatatgga 54660
cgcagatagc tatatgatag ccaactacag aaggcaaacg ctataaaaaa cataattacg 54720
acgagcatat ttataaatat ttttattcag cattacttga tatagtaata ttaggcacag 54780
tcaaacattc aaccactctc gatacattaa ctctctcatt ttctttaaca aattctacaa 54840
tatcttcgta aaaagattct tgaaactttt tagaatatct atcgactcta gatgaaatag 54900
cgttcgtcaa catactatgt tttgtataca taaaggcgcc cattttaaca gtttctagtg 54960
acaaaatgct agcgatccta ggatccttta gaatcacata gattgacgat tcgtctctct 55020
tagtaactct agtaaaataa tcatacaatc tagtacgcga aataatatta tccttgactt 55080
gaggagatct aaacaatcta gttttgagaa catcgataag ttcatcggga atgacataca 55140
tactatcttt aatagaactc ttttcatcca gttgaatgga ttcgtcctta accaactgat 55200
taatgagatc ttctatttta tcattttcca gatgatatgt atgtccatta aagttaaatt 55260
gtgtagcgct tctttttagt ctagcagcca atactttaac atcactaata tcgatataca 55320
aaggagatga tttatctatg gtattaagaa ttcgtttttc gacatctgtc aaaaccaatt 55380
cctttttgcc tgtatcatcc agttttccat cctttgtaaa gaaattattt tctactagac 55440
tattaataag actgataagg attcctccat aattgcacaa tccaaacttt ttaacaaaac 55500
tagactttac aagatctaca ggaatgcgta attcaggttt cttagcttgt gattttttct 55560
tttgtggaca ttttcttgtg accaactcat ctaccatttc attgatttta gcagtgaaat 55620
aagctttcaa tgcacgggca ctgatactat tgaaaacgag ttgatcttca aattccgcca 55680
tttaagttca ccaaacaact tttaaataca aatatatcaa tagtagtaga ataagaacta 55740
taaaaaaaat aataattaac caataccaac cccaacaacc ggtattatta gttgatgtga 55800
ctgttttctc atcacttaga acagatttaa caatttctat aaagtctgtc aaatcatctt 55860
ccggagaccc cataaataca ccaaatatag cggcgtacaa cttatccatt tatacattga 55920
atattggctt ttctttatcg ctatcttcat catattcatc atcaatatca acaagtccca 55980
gattacgagc cagatcttct tctacatttt cagtcattga tacacgttca ctatctccag 56040
agagtccgat aacgttagcc accacttctc tatcaatgat tagtttcttg agtgcgaatg 56100
taatttttgt ttccgttccg gatctataga agacgatagg tgtgataatt gccttggcca 56160
attgtctttc tcttttactg agtgattcta gttcaccttc tatagatctg agaatggatg 56220
attctccagt cgaaacatat tctaccatgg atccgtttaa tttgttgatg aagatggatt 56280
catccttaaa tgttttctct gtaatagttt ccaccgaaag actatgcaaa gaatttggaa 56340
tgcgttcctt gtgcttaatg tttccataga cggcttctag aagttgatac aacataggac 56400
tagccgcggt aacttttatt tttagaaagt atccatcgct tctatcttgt ttagatttat 56460
ttttataaag tttagtctct ccttccaaca taataaaagt ggaagtcatt tgactagata 56520
aactatcagt aagttttata gagatagacg aacaattagc gtattgagaa gcatttagtg 56580
taacgtattc gatacatttt gcattagatt tactaatcga ttttgcatac tctataacac 56640
ccgcacaagt ctgtagagaa tcgctagatg cagtaggtct tggtgaagtt tcaactctct 56700
tcttgattac cttactcatg attaaaccta aataattgta ctttgtaata taatgatata 56760
tattttcact ttatctcatt tgagaataaa aatgtttttg tttaaccact gcatgatgta 56820
cagatttcgg aatcgcaaac caccagtggt tttattttat ccttgtccaa tgtgaattga 56880
atgggagcgg atgcgggttt cgtacgtaga tagtacattc ccgtttttag accgagactc 56940
catccgtaaa aatgcatact cgttagtttg gaataactcg gatctgctat atggatattc 57000
atagattgac tttgatcgat gaaggctccc ctgtctgcag ccatttttat gatcgtcttt 57060
tgtggaattt cccaaatagt tttataaact cgcttaatat cttctggaag gtttgtattc 57120
tgaatggatc caccatctgc cataatccta ttcttgatct catcattcca taattttctc 57180
tcggttaaaa ctctaaggag atgcggatta actacttgaa attctccaga caatactctc 57240
cgagtgtaaa tattactggt atacggttcc accgactcat tatttcccaa aatttgagca 57300
gttgatgcag tcggcatagg tgccaccaat aaactatttc taagaccgta tgttctgatt 57360
ttatctttta gaggttccca attccaaaga tccgacggta caacattcca aagatcatat 57420
tgtagaatac cgttactggc gtacgatcct acatatgtat cgtatggtcc ttccttctca 57480
gctagttcac aactcgcctc taatgcaccg taataaatgg tttcgaagat cttcttattt 57540
agatcttgtg cttccaggct atcaaatgga taatttaaga gaataaacgc gtccgctaat 57600
ccttgaacac caataccgat aggtctatgt ctcttattag agatttcagc ttctggaata 57660
ggataataat taatatctat aattttattg agatttctga caattacttt gaccacatcc 57720
ttcagtttga gaaaatcaaa tcgcccatct attacaaaca tgttcaaggc aacagatgcc 57780
agattacaaa cggctacctc attagcatcc gcatattgta ttatctcagt gcaaagatta 57840
ctacacttga tagttcctaa attttgttga ttactctttt tgttacacgc atccttataa 57900
agaatgaatg gagtaccagt ttcaatctga gattctataa tcgctttcca gacgactcga 57960
gcctttatta tagatttgta tctcctttct ctttcgtata gtgtatacaa tcgttcgaac 58020
tcgtctcccc aaacattgtc caatccagga cattcatccg gacacatcaa cgaccactct 58080
ccgtcatcct tcactcgttt cataaagaga tcaggaatcc aaagagctat aaatagatct 58140
ctggttctat gttcctcgtt tcctgtattc tttttaagat cgaggaacgc cataatatca 58200
gaatgccacg gttccaagta tatggccata actccaggcc gtttgtttcc tccctgatct 58260
atgtatctag cggtgttatt ataaactctc aacattggaa taataccgtt tgatatacca 58320
ttggtaccgg agatatagct tccactggca cgaatattac taattgatag acctattccc 58380
cctgccattt tagagattaa tgcgcatcgt tttaacgtgt catagatacc ctctatgcta 58440
tcatcgatca tgttaagtag aaaacagcta gacatttggt gacgactagt tcccgcatta 58500
aataaggtag gagaagcgtg cgtaaaccat ttttcagaaa gtagattgta cgtctcaata 58560
gctgagtcta tatcccattg atgaattcct actgcgacac gcattaacat gtgctgaggt 58620
ctttcaacga tcttgttgtt tattttcaac aagtaggatt tttccaaagt tttaaaacca 58680
aaatagttgt atgaaaagtc tcgttcgtaa ataataaccg agttgagttt atccttatat 58740
ttgttaacta tatccatggt gatacttgaa ataatcggag aatgtttccc atttttagga 58800
ttaacatagt tgaataaatc ctccatcact tcactaaata gtttttttgt ttccttgtgt 58860
agatttgata cggctattct ggcggctaga atggcataat ccggatgttg tgtagtacaa 58920
gtggctgcta tttcggctgc cagagtgtcc aattctaccg ttgttactcc attatatatt 58980
ccttgaataa ccttcatagc tattttaata ggatctatat gatccgtgtt taagccataa 59040
cataattttc taatacgaga cgtgatttta tcaaacatga cattttcctt gtatccattt 59100
cgtttaatga caaacatttt tgttggtgta ataaaaaaaa ttatttaact tttcattaat 59160
agggatttga cgtatgtagc gtacaaaatt atcgttcctg gtatatagat aaagagtcct 59220
atatatttga aaatcgttac ggctcgatta aactttaatg attgcatagt gaatatatca 59280
ttaggattta actccttgac tatcatggcg gcgccagaaa ttaccatcaa aagcattaat 59340
acagttatgc cgatcgcagt tagaacggtt atagcatcca ccatttatat ctaaaaatta 59400
gatcaaagaa tatgtgacaa agtcctagtt gtatactgag aattgacgaa acaatgtttc 59460
ttacatattt tttttttatt agtaaccgac ttaatagtag gaactggaaa actagacttg 59520
attattctat aagtatagat acccttccaa ataatattct ctttgataaa agttccagaa 59580
aatgtagaat tttttaaaaa gttatctttt gctattacca agattgtgtt tagacgctta 59640
ttattaatat gagtgatgaa atccacaccg cctctagata tcgcttttat ttccacatta 59700
gatggtaaat ccaatagtga aactatcttt ttaggaatgt atggactcgc gtttagagga 59760
gtgaacgtct taggcgtcgg aaaggggccg gccttttttt ctagacacta aataaatagt 59820
aagattaaat taattataaa attatgtata taatattaat tataaaatta tgtatatgat 59880
ttactaactt tagttagata aattaataat acataaattt tagtatatta atattataaa 59940
ttaataatac ataaatttta gtatattaat attatatttt aaatatttat ttagtgtcta 60000
gaaaaaaagg cctagcaggc c 60021
<210> 12
<211> 60021
<212> DNA
<213> 人工序列
<220>
<223> sMVA片段F1
<400> 12
ggcctagcag gccggccttt ttttctagac actaaataaa tagtaagatt aaattaatta 60
taaaattatg tatataatat taattataaa attatgtata tgatttacta actttagtta 120
gataaattaa taatacataa attttagtat attaatatta taaattaata atacataaat 180
tttagtatat taatattata ttttaaatat ttatttagtg tctagaaaaa aatgtgtgac 240
caacgaccgt aggaaactct agagggtaag aaaaatcaat cgctttatag agaccatcag 300
aaagaggttt aatatttttg tgagaccatc gaaggagaaa gagataaaac ttttttacga 360
ctccatcaga aagaggttta atatttttgt gagaccatcg aagagagaaa gagataaaac 420
ttttttacga ctccatcaga aagaggttta atatttttgt gagaccatcg aagagagaaa 480
gagataaaac ttttttacga ctccatcaga aagaggttta atatttttgt gagaccatcg 540
aaggagaaag agataaaact tttttacgac tccatcagaa agaggtttaa tatttttgtg 600
agaccatcga aggagaaaga gataaaactt ttttacgact ccatcagaaa gaggtttaat 660
atttttgtga gaccatcgaa ggagaaagag ataaaacttt tttacgactc catcagaaag 720
aggtttaata tttttgtgag accatcgaag agagaaagag ataaaacttt tttacgactc 780
catcagaaag aggtttaata tttttgtgag accatcgaag gagaaagaga taaaactttt 840
ttacgactcc atcagaaaga ggtttaatat ttttgtgaga ccatcgaaga gagaaagaga 900
ataaaaatat tttagtgaca ccatcagaaa gaggtttaat atttttgtga gaccatcgaa 960
gagagaaaga gataaaactt ttttacgact ccatcagaaa gaggtttaat atttttgtga 1020
gaccatcgaa ggagaaagag ataaaacttt tttacgactc catcagaaag aggtttaata 1080
tttttgtgag accatcgaag agagaaagag ataaaacttt tttacgactc catcagaaag 1140
aggtttaata tttttgtgag accatcgaag agagaaagag ataaaacttt tttacgactc 1200
catcagaaag accatcgaag agagaaagag aaagagatag ttagtctaga tatttttctt 1260
agtacaaaag tcaatgtttt aaaatatatg gacaagaatt tgtctgtata aaaacttgtg 1320
tgaaattttg taccaaagaa aaaatgtgag cagtatcccc tacatggatt ttactagatc 1380
atttatatac caaaaaatat tatacgatct acgttttatt atatgatttt aacgtgtaaa 1440
ttataaacat tattttatga tatacaattg tctggtaacc tagatgggca taggggatga 1500
gtatatgttg ttggacgtta ttgtttaaga aatagttgat gcatcagaaa gaggtttaat 1560
atttttgtga gaccatcgaa gagagaaaga gataaaactt ttttacgact ccatcagaaa 1620
gaggtttaat atttttgtga gaccatcgaa gagagaaaga gataaaactt ttttatgact 1680
ccattgaaga gagaatgaga ataaaaatat tttagtgaca ccatcagaaa gaggtttaat 1740
attttttatg agaccatcaa agagagaaag agaataaaaa tattttatga ctccattgaa 1800
gagagaaaga gaaaatgaga ataaaaatat tttagtgaca ccatcagaaa gaggtttaat 1860
attttttatg agaccatcaa agagagaaag agaataaaaa tatttttgta aaactttttt 1920
tatgagacca tcaaagagag aaagagaata aaaatatttt tgtaaaactt tttttatgag 1980
accatcaaag agagaaagag aataaaaata tttttgtaaa acttttttta tgagaccatc 2040
aaagagagaa agagaataaa aatatttttg taaaactttt tttatgagac catcaaagag 2100
agaaagagaa taaaaatatt tttgtaaaac tttttttatg agaccatcaa agagagaaag 2160
agaataaaaa tatttttgta aaactttttt tatgagacca tcaaagagag aaagagaata 2220
aaaatatttt tgtaaaactt tttttatgag accatcaaag agagaaagag aataaaaata 2280
ttttatgact ccattgaaga gagaaagaga ataaaaatat tttagtgaca ccatcagaaa 2340
gaggtttaat atttttgtga gaccatcgaa gagagaaaga gaataaaaat attttatgac 2400
tccattgaag agagaaagag aataaaaata ttttagtgac accatcagaa agaggtttaa 2460
tattttttat gagaccatca aagagagaaa gagaataaaa atatttttgt aaaacttttt 2520
ttatgagacc atcaaagaga gaaagagaat aaaaatattt ttgtaaaact ttttttatga 2580
gaccatcaaa gagagaaaga gaataaaaat atttttgtaa aacttttttt atgagaccat 2640
caaagagaga aagagaataa aaatattttt gtaaaacttt ttttatgaga ccatcaaaga 2700
gagaaagaga ataaaaatat ttttgtaaaa ctttttttat gagaccatca aagagagaaa 2760
gagaataaaa atattttatg actccattga agagagaatg agaataaaaa tattttagtg 2820
acaccatcag aaagaggttt aatatttttg tgagaccatc gaagagagaa agagaataaa 2880
aatattttat gactccattg aagagagaaa gagaataaaa atattttagt gacaccatca 2940
gaaagaggtt taatattttt tatgagacca tcaaagagag aaagagaata aaaatatttt 3000
tgtaaaactt tttttatgag accatcaaag agagaaagag aataaaaata tttttgtaaa 3060
acttttttta tgagaccatc aaagagagaa agagaataaa aatatttttg taaaactttt 3120
tttatgagac catcaaagag agaaagagaa taaaaatatt tttgtaaaac tttttttatg 3180
agaccatcaa agagagaaag agaataaaaa tatttttgta aaactttttt tatgagacca 3240
tcaaagagag aaagagaata aaaatatttt tgtaaaactt tttttatgag accatcaaag 3300
agagaaagag aataaaaata tttttgtaaa acttttttta tgagaccatc aaagagagaa 3360
agagaataaa aatattttat gactccattg aagagagaat gagaataaaa atattttagt 3420
gacaccatca gaaagaggtt taatattttt gtgagaccat cgaagagaga aagagaataa 3480
aaatatttta tgactccatt gaagagagaa tgagaataaa aatattttag tgacaccatc 3540
agaaagaggt ttaatatttt ttatgagacc atcaaagaga gaaagagaat aaaaatattt 3600
ttgtaaaact ttttttatga gaccatcaaa gagagaaaga gaataaaaat atttttgtaa 3660
aaattataaa cattatttta tgatatacaa ttgtctggta acctagatgg gcatagggga 3720
tgttgataag ctcgacgagt atatgttgtt ggacgttatt gtttaagaaa tagttgatgc 3780
atcagaaaga gaataaaaaa tattttagtg agaccatcga agagagaaag agataaaact 3840
tttttacgac tccatcagaa agaggtttaa tatttttgtg agaccatcga agagagaaag 3900
agataaaact tttttacgac tccatcagaa agaggtttaa tatttttgtg agaccatcga 3960
aggagaaaga gataaaactt ttttacgact ccatcagaaa gaggtttaat atttttgtga 4020
gaccatcaaa gagagaaaga gaataaaaat atttttgtaa aacttttttt atgagaccat 4080
caaagagaga aagagaataa aaatattttt gtaaaacttt ttttatgaga ccatcaaaga 4140
gagaaagaga ataaaaatat ttttgtaaaa ctttttttat gagaccatca aagagagaaa 4200
gagaataaaa atatttttgt aaaacttttt ttatgagacc atcaaagaga gaaagagaat 4260
aaaaatattt tatgactcca ttgaagagag aatgagaata aaaatatttt agtgacacca 4320
tcagaaagag gtttaatatt tttgtgagac catcgaagag agaaagagaa taaaaatatt 4380
ttatgactcc attgaagaga gaatgagaat aaaaatattt tagtgacacc atcagaaaga 4440
ggtttaatat tttttatgag accatcaaag agagaaagag aataaaaata tttttgtaaa 4500
acttttttta tgagaccatc aaagagagaa agagaataaa aatatttttg taaaactttt 4560
tttatgagac catcaaagag agaaagagaa taaaaatatt tttgtaaaac tttttttatg 4620
agaccatcaa agagagaaag agaataaaaa tatttttgta aaactttttt tatgagacca 4680
tcaaagagag aaagagaata aaaatatttt atgactccat tgaagagaga atgagaataa 4740
aaatatttta gtgacaccat cagaaagagg tttaatattt ttgtgagacc atcgaagaga 4800
gaaagagaat aaaaatattt tatgactcca ttgaagagag aaagagaata aaaatatttt 4860
agtgacacca tcagaaagag gtttaatatt ttttatgaga ccatcaaaga gagaaagaga 4920
ataaaaatat ttttgtaaaa ctttttttat gagaccatca aagagagaaa gagaataaaa 4980
atattttatg actccattga agagagaatg agaataaaaa tattttagtg acaccatcag 5040
aaagaggttt aatatttttg tgagaccatc gaagagagaa agagaataaa aatattttat 5100
gactccattg aagagagaat gagaataaaa atattttagt gacaccatca gaaagaggtt 5160
taatattttt gtgagaccat cgaagagaga aagagaataa aaatatttta tgactccatt 5220
gaagagagaa tgagaataaa aatattttag tgacaccatc agaaagaggt ttaatatttt 5280
ttatgagacc atcaaagaga gaaagagaat aaaaatattt ttgtaaaact ttttttatga 5340
gaccatcaaa gagagaaaga gaataaaaat atttttgtaa aacttttttt atgagaccat 5400
caaagagaga aagagaataa aaatattttt gtaaaacttt ttttatgaga ccatcaaaga 5460
gagaaagaga ataaaaatat ttttgtgaga ccatcaaaga gagaaagaga ataaaaatat 5520
ttttgtgaga ccatcaaaga gagaaagaga ataaaaatat ttttgtgaga ccatcaaaga 5580
gagaaagaga ataaaaatat tttatgactc cattgaagag agaaagagaa taaaaatatt 5640
ttagtgacac catcagaaag aggtttaata tttttgtgag accatcgaag agagaaagag 5700
aataaaaata ttttatgact ccattgaaga gagaaagaga ataaaaatat tttagtgaca 5760
ccatcagaaa gaggtttaat attttttatg agaccatcaa agagagaaag agaataaaaa 5820
tattttttat gagaccatca aagagagaaa gagaataaaa atattttatg agaccatcaa 5880
agagagaaag agaataaaaa tattttttat gagaccatca aagagagaaa gagaataaaa 5940
atattttatg agaccatcaa agagagaaag agaataaaaa tattttttat gagaccatca 6000
aagagagaaa gagaataaaa atatttttgt atgagaccat cagaaagagg tttaatattt 6060
ttgtgatacc ctgaaaggaa ataggaatag tgtcataatc gtatcacact attgagacag 6120
aaaaagaaga agtcgcgaga ggtaactttt tgttttgcaa accggaatat agtgtccggt 6180
acactttttt aattcgtggt gtgcctgaat cgttcgatta accctactca tccaatttca 6240
gatgaataga gttatcgatt cagacacacg ctttgagttt tgttgaatcg atgagtgaag 6300
tatcatcggt tgcaccttca gatgccgatc cgtcgacata cttgacctca agttcagatg 6360
attccttgca catgtctccg atacgaacgc taaactctag attcttgaca cattttgtat 6420
cgacgatcgt tgaaccgatg atatcttcgt aactcacttt cttatgagag atgttagacc 6480
cgagtactgg atgggtcttg atgtcgctgt ctttctcttc ttcgctacat ctgatgtcga 6540
tagacacctc acagtctttc catcagcgga ttctgagatg gatttaatct gaggacattt 6600
ggtgaatcca aagttcattc tcagacctcc accgatgatg gagtaataag tggtaggagg 6660
atctacatcc tcgactgatt ccacctcggg atctggatct gactcggact ctgtaatttc 6720
cgttacggat tggcaaatct tatcatcggt cggtgtttgg tcttgctttg tgactttgat 6780
aataacatcg attcccatat gatgtttgtt ttcttcttcc gtacacgatg aggatgattg 6840
ctgaagactg gcaggcacat gcatgccagt acgatatatt gtttcatgat tgctattgat 6900
tgagtactgt tctttatgat tctacttcct taccgtgcaa taaattagaa tatattttct 6960
acttttacga gaaattaatt attgtattta tgggtgaaaa acttactata aaaagcgggt 7020
gggtttggaa ttagtgatca gtttatgtat atcgcaacta ccgggcatat ggctacatta 7080
cccacatgat aagagattgt atcagtttcg tagtcttgag tattggtatt actatatagt 7140
atatagatgt cgacgctaga gttactgtct ccgaatgcgg catgatagta tcattctttg 7200
ctttcgttaa ctgtttggag gaagaatctt tgttattgca tttaatctcg aaattcagag 7260
tgcacacctt tctcctgtaa agaaacctga agtcgctacc ttattaagaa gacgggatcg 7320
cagtctttat gattcatagt aatagttagt tccgacgttg agatggattc gctgagaccg 7380
gtagtggtcg tccgagtaca cgatgtgtcg ttaactggat acaggttaat ttccacatcg 7440
atatagttaa aggtatttct gggtacgggt tcgcatttat ctgcggaaga gacggtgtga 7500
gaatatgttc cgagaccaca cggagaacag atgacgtctc cggatactcc gtatcctatt 7560
ccacattttg tttgggaaac acatgccttg catccatgat cgggagagca ttcacagatt 7620
ctattgtgag tcgtgttaca cgatcgcgtc gacattgttg acagaaacgt gaccttcatt 7680
cttaccgtcg tccataaata cgttaggtat gtaccacata ctgtcgcgaa cgatgcgtcc 7740
atctcataat gatttacttt ttcataatta aagatgtgaa agaaaaccga acaatatatt 7800
tttttagtaa tgtttatgcg agacatataa aataaactcc gtgtttatga tgccggtaaa 7860
tgtttttatc atcttggacg gaatcgattt tgtaatatgc catggaaaca ggacattatc 7920
actccatgat aaattattta atggagtcga tcctctcatt gttctttgcg tatctcaatc 7980
tgtggcgttt gcttcgttta aataatatat caaacatgga gacgcctgat atgtaggcat 8040
tcttcattct attaatgtct gctctatagc gctttagttc cttatgacga ccggcgatat 8100
catacttact ttagaaggaa aatcatcatc taggattaag gcgtatctga tacaggcgaa 8160
taatggttca ggatatagat agcgtatatc tctattaaat gcgtcaatca tagtctctag 8220
agtgggatgg taactcagta ataaatcaac tagcttctct ttggtaactg cttttctgga 8280
tggccgtatt gattatcgag cgtgacactc gctccatatt ccaataaccg ctttgcaaat 8340
tgtatattat tgacatcgac cgcgtaatat agtagagtta tcgatcatat ctatatcatc 8400
catgtacttg cttagtatat caaatacatc ttcataacag tgatacccgc aattattaaa 8460
tctcgataat atcagaccgt acatacatag acggccattg ttagatatgt gatttacagc 8520
cgcgtgtcca tattttccac gataaacctt acgacgttta catcgacgag attattatta 8580
acaaagttgt tgtccgtcgt cttatccaac atgcattgaa tgataggtat acttaccata 8640
tcgccgtaat gtaagtagtt tatcagtatg gcttgtacga tggattcatc ctgttgtcta 8700
aatctcttta gaatgttatc gatgatgtag tggttatatt ctctggaatc gtacgaagta 8760
atactacgca ttacgtcgac aagagtatga cgtctctcaa taagaagatt aacgatttcc 8820
atgtctacat tatatggggt tactctaaat cgcttgttta gataatacgc ctctaatata 8880
gggctgacgt cgtatactct acacgtgtcc acatccttta ttaataatct ctatatctat 8940
ggttgagcaa gaccagtagt attggatgga aacattgtta tcgatcaaac atttaattac 9000
atccttggat agagattctc tatgagacga tatatagtaa tgaagagagt tcttacacat 9060
atcactgttg tacatacagg tacgaaatac gtaaccggtg ctgtaacatt ctgatttaag 9120
aagccatagc aatacttctg gtctcggatt aggcgtcgtt acgtatatat ccaccaatcc 9180
gagaccattg attgcataat tcgtattctt ggacggacgt atccgtttat ccacaattag 9240
gtattttagc agacgtaagt cgaaatcatt tatattcgac ttgagttcgt tagaggaatt 9300
cgaatagctg gatatcagta gatgcacaat ctgagatttt acgtatctat gcttactgta 9360
tgctcctagc ggagttaatc cttcgttgtt tctacaaagt ctctcgactc cgcgagagag 9420
taacagtcga acaatcttaa tgtctgtatc gcatttattg gagacgtaac aatgtagcgc 9480
attgtttcct cgtctatcta tatgttttga taagttgtga cacgtttcaa tttctagttt 9540
tatttttttg tacgtcacat cttcatccag tagacgacat agaatacatg tgcaatccat 9600
agctattctg gtgctaatta ttcctcataa gatgataaaa agtgtagtga gagagcatga 9660
aggagattta gtatttagca gtgcggatat gatccaagag ggtgagatag tcgttctcgt 9720
tcagaatctt tcgcagcata agtagtatgt cgatatactt atcgttgaag actcttccag 9780
agacgatagc tgattgagta caaagtccaa tgattgcacg aagttcttcg gcggttttca 9840
tggagtcatt tctgatgaaa catttaatga tctaaatttc agtttatgtt tgtaccccgt 9900
attcatactt aacaaattgg tattacatac cattaataat gcaagcataa aaaatcgtta 9960
gtagatgttt ctaaatatag gttccgtaag caaagaatat aagaatgaag cggtaatgat 10020
aaaatcaatc gttatctaaa atgatcatac tcatttattt tattctatta tattaacaca 10080
tacattttta acagcaacac attcaatatt gtattgttat ttttatatta tttacacaat 10140
taacaatata ttattagttt atattactga attaataata taaaattccc aatcttgtca 10200
taaacacaca ctgagaaaca gcataaacac aaaatccatc aaaaatgttg ataaattatc 10260
tgatgttgtt gttcgctgct atgataatca gatcattcgc cgatagtggt aacgctatcg 10320
aaacgacatc gccagaaatt acaaacgcta caacagatat tccagctatc agattatgcg 10380
gtccagaggg agatggatat tgtttacacg gtgactgtat ccacgctaga gatatcgacg 10440
gtatgtattg tagatgctct catggttata caggcattag atgtcagcat gtagtattag 10500
tagactatca acgttcagaa aaaccaaaca ctacaacgtc atatatccca tctcccggta 10560
ttatgcttgt attagtaggc attattatta ttacgtgttg tctattatct gtttataggt 10620
tcactcgacg aactaaacta cctatacaag atatggttgt gccataattt ttataaattt 10680
tttttatgag tatttttaca aaaatgtata aagtgtatgt cttatgtata tttataaaaa 10740
tgctaaatat gcgatgtatc tatgttattt gtatttatct aaacaatacc tctacctcta 10800
gatattatac aaaaattttt tatttcggca tattaaagta aaatctagtt accttgaaaa 10860
tgaatacagt gggtggttcc gtatcaccag taagaacata atagtcgaat acagtatccg 10920
attgagattt tgcatacaat actagtctag aaagaaattt gtaatcatct tctgtgacgg 10980
gagtccatat atctgtatca tcgtcccatg ctatattcct gttatcatca ttagttaatg 11040
aaaataactc tcgtgcttca gaaaagtcaa atattgtatc catacataca tctccaaaac 11100
tatcgcttat acgtttatct ttaacgatac ctatacctag atggttattt actaacagac 11160
attttccaga tctattgact ataactccta tagtttccac atcaaccaag taatgatcat 11220
ctattgttat ataacaataa cataactctt ttccgttttt atcagtatgt atatctatat 11280
caacgtcgtc gttgtagtga atagtagtca ttgatctatt atatgaaacg gatatgtcta 11340
gaacggcaat tgttttacgt ccagttaaca ctttcgttga tttaaagtct agagtctttg 11400
caaacataat atccttatcc gactttatat ttcctgtagg gtggtataat tttattttgc 11460
ctccacatat cggtgtttcc aaatatatta ctagacaata ttccatatag ttattagtta 11520
agggtaccca attagaacac gtacgcttat tatcatcatt tggatcgtat ttcataaaag 11580
ttattgtact atcgatgtca acacattcta cattttttaa tcgtctatat agtatttttc 11640
tgatattttc tataatatca gaattgtctt ccatcggaag ttgtatacta tcggaatcag 11700
ttacatgttt aaataattct ctgatgtcat tccttataca atcaaattca ttattaaaca 11760
gtttaatagt ctgtagacct ttatcgtcgt aaatatccat tgtcttatta gttacgctta 11820
tttttatgtg tttttacgtt gctttattat attttataag aatgattgtt tgacgaatca 11880
cgagaactat taagacacat tattaggtat atattataaa aaagtttttg attacgatgt 11940
tataagagga aagaggacac attaacatca tacatcaatt aactacattc ttataacatc 12000
gtaatcaaaa gaattgcaat tttgatgtat aacaactgtc aatgggttat ggaattgtat 12060
attacatatt atacggtatg ttggtaacga caaataccga tcggtaattg tctgccggtg 12120
taatagaatt atatatatct atctattaca ccggccttgt atacataata ataagttgtg 12180
gtagtatgat ctccatattt ataatttagg actttgtatt cagttttttt ggaatcataa 12240
aaaataaaaa aaagttttac taatttaaaa ttatttacat ttttttcact gtttagtcgc 12300
ggatatggaa ttcgatcctg ccaaaatcaa tacatcatct atagatcatg taacaatatt 12360
acaatacata gatgaaccaa atgatataag actaacagta tgcattatca caaaaataaa 12420
tccacatttg gctaatcaat ttcgggcttg gaaaaaacgt atcgccggaa gggactatat 12480
gactaactta tctagagata caggaataca acaatcaaaa cttactgaaa ctgtcaaaaa 12540
aatagaaaca tatatggtct atatatacac tacaatttag ttattaattg gataaccgat 12600
gtgattatca atcaatatta agaaggttgg taaattggta catagctaat aatacctata 12660
cacccaataa tacaacaacc atttctgagt tggatatcat caaaatactg gataaatacg 12720
aggacgtgta tagagtaagt aaagaaaaag aatgtgaaat ttgctatgaa gttgtttact 12780
caaaacgata gatactttgg tttattggat tcgtgtaatc atatattttg cataacatgc 12840
atcaatatat ggcatagaac acgaagagaa accggtgcgt cggataattg tcctatatgt 12900
cgtacccgtt ttagaaacat aacaatgagc aagttaacta ataaataaaa agtttaattt 12960
gttgacgacg tatgtcgtta ttttttctcg tataaaagat taatttgatt ctaatataat 13020
ctttagtatt ggataaatat caattcaaat taattccatt agattatatc ataaataaaa 13080
atagtagcac gcactacttc agccaaatat tcttttttga aacgccatct atcgtagtga 13140
ggacacaagt gaacctataa tgagcaaatt tattagtatc ggttacatga aggactttac 13200
gtagagtggt gattccacta tctgtggtac gaacggtttc atcttctttg atgccatcac 13260
ccagatgttc tataaacttg gtatcctttg ccaaccaata catatagcta aactcaggca 13320
tatgttccac acatcctgaa caatgaaatt ctccagaaga tgttacaatg tctagatttg 13380
gacatttggt ttcaaccgcg ttaacatatg agtgaacaca cccatacatg aaagcgatga 13440
gaaataggat tttcatcttg ccaaaatatc actagaaaaa atttatttat caattttaaa 13500
ggtataaaaa atacttattg ttgctcgaat attttgtatt tgatggtata cggaagatta 13560
gaaatgtagg tattatcatc aactgattct atggttttat gtattctatc atgtttcact 13620
attgcgttgg aaataatatc atatgcttcc acatatattt tattttgttt taactcataa 13680
tactcacgta attctggatt attgacatat ctatgaataa ttttagctcc atgatcagta 13740
aatattaatg agaacatagt attaccacct accattattt ttttcatctc attcaattct 13800
taattgcaaa gatctatata atcattatag cgttgactta tggactctgg aatcttagac 13860
gatgtacagt catctataat catggcatat ttaatacatt gttttatagc atagtcgtta 13920
tctacgatgt tagatatttc tctcaatgaa tcaatcacac aatctaatgt aggtttatga 13980
cataatagca ttttcagcag ttcaatgttt ttagattcgt tgatggcaat ggctatacat 14040
gtatatccgt tatttgatct aatgttgaca tctgaaccgg attctagcag taaagatact 14100
agagattgtt tattatatct aacagccttg tgaagaagtg tttctcctcg tttgtcaatc 14160
atgttaatgt ctttaagata aggtaggcaa atgtttatag tactaagaat tgggcaagca 14220
taagacatgt cacaaagacc ctttttgtat gtataagtgt aaaaattata acattcatag 14280
ttggatttac ataggtgtcc aatcgggatc tctccatcat cgagataatt gatggcatct 14340
cccttccttt tttagtagat atttcatcgt gtaagaatca atattaatat ttctaaagta 14400
tccgtgtata gcctctttat ttaccacagt tccatattcc actagaggga tatcgccgaa 14460
tgtcatatac tcaattagta tatgttggag gacatccgag ttcattgttt tcaatatcaa 14520
aaagatggtt tccttatcat ttctccatag tggtacaata ctacacatta ttccgtgcgg 14580
ctttccattt tccaaaaaca atttgaccaa atctacatct ttattgtatc tataatcact 14640
atttagataa tcagccataa ttactcgagt gcaacatgtt agatcgtcta tatatgaata 14700
agccgtgtta tctattcctt tcattaacaa tttaacgatg tctatatcta tatgagatga 14760
cttaatataa tattgaagag ctgtacaata gtttttatct ataaaagacg gcttgattcc 14820
gtgattaatt agacatttaa caacttccgg acgcacatat gctctcgtat ccgactctga 14880
atacagatga gagatgatat acagatgcaa tacggtaccg caatttcgta gttgataatc 14940
atcatacgcg tatcagtact cgtcctcata aagaacactg cagccatttt ctatgaacaa 15000
atcaataatt tcaggaacag gatcatctgt cattacataa ttttctataa ctgaacgatg 15060
gttttcacat ttaacactca agtcaaatcc atgttctacc aacaccttta tcaagtcaac 15120
gtctacattt ttggatttca tatagctgaa tatattaaag tcatttatgt tgctaaatcc 15180
agtggcttct agtagagcca tcgctatatc ctttaacttt aacatgtcta ctatttgtgt 15240
attcttctaa tggggtagct gtctccaatt tttgcgtaat ggattagtgc cactgtctag 15300
tagtagtttg acgacctcga cattattaca atgctcatta aaaaggtatg cgtgtaaagc 15360
attattcttg aattggttcc tggtatcatt aggatctctg tctctcaaca tctgtttaag 15420
ttcatcgaga gccacctcct cattttccaa atagtcaaac attttgactg aatgagctac 15480
tgtgaactct atacacccac acaactaatg tcattaaata tcatgtcaaa aacttgtaca 15540
attattaata aaaataattt agtgtttaaa ttttaccagt tccagatttt acacctccgt 15600
taaccccact ttttacacca ctggacgatc ctcctcccca cattccaccg ccaccagatg 15660
tataagtttt agatccttta ttactaccat catgtccatg gataaagaca ctccacatgc 15720
cgccactacc ccctttagaa gacatattaa taagacttaa ggacaagttt aacaataaaa 15780
ttaatcacga gtaccctact accaacctac actattatat gattatagtt tctattttta 15840
cagtacctta actaaagtct ctagtcacaa gagcaatact accaacctac actattatat 15900
gattatagtt tctattttta taggaacgcg tacgagaaaa tcaaatgtct aatttctaac 15960
ggtagtgttg ataaacgatt atcgtcaatg gatacctcct ctatcatgtc gtctattttc 16020
ttactttgtt ctattaactt attagcatta tatattattt gattataaaa cttatattgc 16080
ttattagccc aatctgtaaa tatcggatta ttaacatatc gtttctttgt aggtttattt 16140
aacatgtaca tcactgtaag catgtccgta ccatttattt taatttgacg catatccgca 16200
atttcttttt cgcagtcggt tataaattct atatatgatg gatacatgct acatgtgtac 16260
ttataatcga ctaatatgaa gtacttgata catattttca gtaacgattt attattacca 16320
cctatgaata agtacctgtg atcgtctagg taatcaactg ttttcttaat acattcgatg 16380
gttggtaatt tactcagaat aatttccaat atcttaatat ataattctgc tatttctggg 16440
atatatttat ctgccagtat aacacaaata gtaatacatg taaacccata ttttgttatt 16500
atattaatgt ctgcgccatt atctattaac cattctacta ggctgacact atgcgactta 16560
atacaatgat aaagtatact acatccatgt ttatatcatc aatatacggc ttacaaagtt 16620
ttagtatcga taacacatcc aactcacgca tagagaaggt agggaataat ggcataatat 16680
ttattaggtt atcatcattg tcattatcta caactaagtt tccatttttt aaaatatact 16740
cgacaacttt aggatctcta ttgccaaatt tttgaaaata tttatttata tgcttaaatc 16800
tatataatgt agctccttca tcaatcatac atttaataac attgatgtat actgtatgat 16860
aagatacata ttctaacaat agatcttgta tagaatctgt atatctttta agaattgtgg 16920
atattattac gtaaactatt acacaattct aaaatataaa acgtatcacg gtcgaataat 16980
agttgatcaa ctatataatt atcgattttg tgatttttct tcctaaactg tttacgtaaa 17040
tagttagata gaatattcat tagttcatga ccactatagt tactatcgaa taacgcgtca 17100
aatatttccc gtttaatatc gcatttgtca agataataat agagtgtggt atgttcacga 17160
taagtataat aacgcatctc tttttcgtgt gaaattaaat agtttattac gtccaaagat 17220
gtagcataac catcttgtga cctagtaata atataataat agagaactgt tttacccatt 17280
ctatcatcat aatcagtggt gtagtcgtaa tcgtaattgt ctaattcatc atcccaatta 17340
taatattcac cagcacgtct aatctgttct attttgatct tgtatccata ctgtatgttg 17400
ctacatgtag gtattccttt atccaataat agtttaaaca catctacatt gggatttgat 17460
gttgtagcgt atttttctac aatattaata ccatttttga tactatttat ttctatacct 17520
ttcgaaatta gtaatttcaa taagtctata tcgatgttat cagaacatag atattcgagt 17580
atatcaaaat cattgatatt tttatagtcg actgacgaca ataacaaaat cacaacatcg 17640
tttttgatat tattattttt cttggtaacg tatgccttta atggagtttc accatcatac 17700
tcatataatg gatttgcacc actttctatc aatgattgtg cactgctggc atcgatgtta 17760
aatgttttac aactatcata gagtatctta tcgttaacca tgattggttg ttgatgctat 17820
cgcatttttt ggtttctttc atttcagtta tgtatggatt tagcacgttt gggaagcatg 17880
agctcatatg atttcagtac tgtagtgtca gtactattag tttcaataag atcaatctct 17940
agatctatag aatcaaaaca cgataggtca gaagataatg aatatctgta ggcttcttgt 18000
tgtactgtaa cttctcgttt tgttagatgt ttgcatcgtg ctttaacatc aatggtacaa 18060
attttatcct cgctttgtgt atcatattcg tccctactat aaaattgtat attcagatta 18120
tcatgagatg tgtatacgct aacggtatca ataaacggag cacaccattt agtcataacc 18180
gtaatccaaa aatttttaaa gtatatctta acgaaagaag ttgtgtcatt gtctacggtg 18240
tatggtacta gatcctcata agtgtatata tctagagtaa tgtttaattt atcaaatggt 18300
tgataatatg gatcctcatg acaatttccg aagatggaaa tgagatatag acatgcaata 18360
aatctaattg cggacatggt tactccttaa aaaaatacga ataatcacct tggctattta 18420
gtaagtgtca tttaacacta tactcatatt aatccatgga ctcataatct ctatacggga 18480
ttaacggatg ttctatatac ggggatgagt agttttcttc tttaacttta tactttttac 18540
taatcatatt tagactgatg tatgggtaat agtgtttaaa gagttcgttc tcatcatcag 18600
aataaatcaa tatctctgtt tttttgttat acagatgtat tacagcctca tatattacgt 18660
aatagaacgt gtcatctacc ttattaactt tcaccgcata gttgtttgca aatacggtta 18720
atcctttgac ctcgtcgatt tccgaccaat ctgggcgtat aatgaatcta aactttaatt 18780
tcttgtaatc attcgaaata atttttagtt tgcatccgta gttatcccct ttatgtaact 18840
gtaaatttct caacgcgata tctccattaa taatgatgtc gaattcgtgc tgtataccca 18900
tactgaatgg atgaacgaat accgacggcg ttaatagtaa tttacttttt catctttaca 18960
tattgggtac tagttttact atcataagtt tataaattcc acaagctact atggaataag 19020
ccaaccatct tagtataaca cacatgtctt aaagtttatt aattaattac atgttgtttt 19080
atatatcgct acgaatttaa acagagaaat cagtttagga aaaaaaaata tctatctaca 19140
tcatcacgtc tctgtattct acgatagagt gctactttaa gatgagacat atccgtgtca 19200
tcaaaaatat actccattaa aatgattatt ccggcagcga acttgatatt ggatatatca 19260
caacctttgt taatatctac gacaatagac agcagtccca tggttccata aacagtgagt 19320
ttatctttct ttgaagagat attttgtaga gatcttataa aactgtcgaa tgacatcgca 19380
tttatatctt tagctaaatc gtatatgtta ccatcgtaat atctaaccgc gtctatctta 19440
aacgtttcca tcgctttaaa gacgtttccg atagatggtc tcatttcatc agtcatactg 19500
agccaacaaa tataatcgtg tataacatct ttgatagaat cagactctaa agaaaacgaa 19560
tcggctttat tatacgcatt catgataaac ttaatgaaaa atgtttttcg ttgtttaagt 19620
tggatgaata gtatgtctta ataattgtta ttatttcatt aattaatatt tagtaacgag 19680
tacactctat aaaaacgaga atgacataac tagttatcaa agtgtctagg acgcgtaatt 19740
ttcatatggt atagatcctg taagcattgt ctgtattctg gagctatttt ctctatatct 19800
aatttctgaa cgttcaccaa tgtctctagc cactttggca ctaatagcga tcattcgctt 19860
agcgtcttct atattattaa ctggttgatt caatctatct agcaatggac cgtcggacag 19920
cgtcattctc atgttcttaa tcaatgtaca tacatcgccg tcatctacca attcatccaa 19980
caacataagc tttttaaaat catcattata ataggtttga tcgttgtcat ttctccaaag 20040
aatatatcta ataagtagag tcctcatgat tagttaacaa ctatttttta tgttaaatca 20100
attagtacac cgctatgttt aatacttatt catattttag tttttaggat tgagaatcaa 20160
tacaaaaatt aatgcatcat taattttaga aatacttagt ttccacgtag tcaatgaaac 20220
atttgaactc atcgtacagg acgttctcgt acaggacgta actataaacc ggtttatatt 20280
tgttcaagat agatacaaat ccgataactt tttttacgaa ttctacggga tccactttaa 20340
aagtgtcata ccgggttctt tttatttttt taaacagatt aatggtgtga tgttgattag 20400
gtcttttacg aatttgatat agaatagcgt ttacatattc tccataatgg tcaatcgcca 20460
tttgttcgta tgtcataaat tctttaatta tatgacactg tgtattattt agttcatcct 20520
tgttcatcat taggaatcta tccaatatgg caattatact agaactatag gtgcgttgta 20580
tacacatatt gatgtgtctg tttatacaat ccatgctact accttcgggt aaaattgtag 20640
catcatatac catttctagt actttaggtt cattgttatc cattgcagag gacgtcatga 20700
acgcatccta aaaaaatata ttatttttat gttattttgt taaaaataat catcgaatac 20760
gaatcatcca gtccactgaa tagcaaaatc tttactattt tggtatcttc caatgtggct 20820
gcctgatgta atggaaattc attctctaga agatttttca atgctccagc gttcaacaac 20880
gtacatacta gacgcacgtt attatcagct attgcataat acaaggcact atgtccatgg 20940
acatccgcct taaatgcatc tttgctagag agaaagcttt tcagctgctt agacttccaa 21000
gtattaattc gtgacagatc catgtctgaa acgagacgct aattagtgta taatttttgt 21060
catattgcac cagaattaat aatatctcta atagatctga ttagtagata catggctatc 21120
gcaaaacaac atatacacat ttaataaaaa taatatttat taagaaaatt cagatttcac 21180
gtacccatca atataaataa aataatgatt ccttacaccg tacccatatt aaggagattc 21240
taccttaccc ataaacaata taaatccagt aatatcatgt ctgatgatga acacaaatgg 21300
tgtattaaat tccagttttt caggagatga tctcgccgta gctaccataa tagtagatgc 21360
ctctgctaca gttccttgtt cgtcgacatc tatctttgca ttctgaaaca ttttataaat 21420
atataatggg tccctagtca tatgtttaaa cgacgcatta tctggattaa acatactagg 21480
agccatcatt tcggctatcg acttaatatc cctcttattt tcgatagaaa atttagggag 21540
tttaagattg tacactttat tccctaattg aaacgaccaa tagtctaatt ttgcagccgt 21600
aatagaatct gtgaaatggg tcatattatc acctattgcc aggtacatac taatattagc 21660
atccttatac ggaaggcgta ccatgtcata ttctttgtca tcgattgtga ttgtatttcc 21720
ttgcaattta gtaactacgt tcatcatggg aaccgttttc gtaccgtact tattagtaaa 21780
actagcattg cgtgttttag tgatatcaaa cggatattgc catatacctt taaaatatat 21840
agtattaatg attgcccata gagtattatt gtcgagcata ttagaatcta ctacattaga 21900
cataccggat ctacgttcta ctatagaatt aattttatta accgcatctc gtctaaagtt 21960
taatctatat aggccgaatc tatgatattg ttgataatac gacggtttaa tacacacagt 22020
attatctacg aaactttgat aagttagatc agtgtacgta tatttagatg ttttcagctt 22080
agctaatcct gatattaatt ctgtaaatgc tggacccaga tctctttttc tcaaatccat 22140
agtcttcaat aattctattc tagtattacc tgatgcaggc aatagcgaca taaacataga 22200
aaacgaataa ccaaacggtg agaagacaat attatcatct tgaatatttt tatacgctac 22260
tataccggca ttggtaaatc cttgtagacg ataggtagac gctgaacacg ttaacgatag 22320
tatcaataac gcaatcatga ttttatggta ttaataatta accttatttt tatgttcggt 22380
ataaaaatta ttgatgtcta cacatccttt tgtaattgac atctatatat ccttttgtat 22440
aatcaactct aatcacttta acttttacag ttttccctac cagtttatcc ctatattcaa 22500
catatctatc catatgcatc ttaacactct ctgccaagat agcttcagag tgaggatagt 22560
caaaaagata aatatataga gcataatcat tctcgtatac tctgcccttt attacatcgc 22620
ccgcattggg caacgaataa caaaatgcaa gcatcttgtt aacgggctcg taaattggga 22680
taaaaattat gtttttatat ctattttatt caagagaata ttcaggaatt tctttttccg 22740
gttgtatctc atcgcagtat atatcatttg tacattgttt catatttttt aatagtttac 22800
accttttagt aggactagta tcgtacaatt catagctgta ttttgaattc caatcacgca 22860
taaaaatatc ttctaattgt tgacgaagac ctaatccatc atccggtgta atattaatag 22920
atgctccaca tgtatccgta aagtaatttc ctgtccaatt tgaggtacct atataggccg 22980
ttttatcggt taccatatat ttggcatggt ttaccctaga atacggaatg ggaggatcag 23040
catctggtac aataaatagc tttacttcta tatttatgtt tttagatttt agcatagcga 23100
tagatcttaa aaagtttctc atgataaacg aagatcgttg ccagcaacta atcaatagct 23160
taacggatac ttgtctgtct atagcggatc ttcttaattc atcttctata taaggccaaa 23220
acaaaatttt acccgccttc gaataaataa tagggataaa gttcataaca gatacataaa 23280
cgaatttact cgcatttcta atacatgaca ataaagcggt taaatcattg gttctttcca 23340
tagtacatag ttgttgcggt gcagaagcaa taaatacaga gtgtggaaca ccacttacgt 23400
taatactaag aggatgatct gtattataat acgacggata aaagtttttc caattatatg 23460
gtagattgtt aactccaaga taccagtata cctcaaaaat ttgagtgaga tccgctgcca 23520
agttcctatt attgaagatc gcaataccca attctttgac ctgagttagt gatctccaat 23580
ccatgttagc gcttcctaaa taaatatgtg tattatcaga tatccaaaat tttgtatgaa 23640
gaactcctcc taggatattt gtaatatcta tgtatcgtac ttcaactccg gccatttgta 23700
gtctttcaac atcctttaat ggtttgttag atttattgac ggctactcta actcgtactc 23760
ctcttttggg taattgtaca atctcgttta atattatcgt gccgaaattc gtacccactt 23820
catccgataa actccaataa aaagatgata tatctagtgt ttttgtggta ttggatagaa 23880
tttccctcca catgttaaat gtagacaaat atactttatc aaattgcata cctataggaa 23940
tagtctctgt aatcactgcg attgtattat ccggattcat tttatttgtt aaaagaataa 24000
tcctatatca cttcactcta ttaaaaatcc aagtttctat ttctttcatg actgattttt 24060
taacttcatc cgtttcctta tgaagatgat gtttggcacc ttcataaatt tttatttctc 24120
tattacaatt tgcatgttgc atgaaataat atgcacctaa aacatcgcta atctcattgt 24180
ttgttccctg gagtatgaga gtcggggtgt taatcttgga aattattttt ctaaccttgt 24240
tggtagcctt caagacctga ctagcaaatc cagccttaat tttttcatga ttgattaatg 24300
ggtcgtattg gtatttataa actttatcca tatctctaga tactgattct ggacatagct 24360
ttccgactgg cgcatttggt gtgatggttc ccataagttt ggcagctagc agattcagtc 24420
ttgaaacagc atctgcatta actagaggag acattagaat cattgctgta aacaagtttg 24480
gattatcgta agaggctagt atagaaattg ttgctcccat ggaatgaccc aataagtaga 24540
tttaatagtt accacgtgct gtaccaaagt catcaatcat cattttttca ccattacttc 24600
ttccatgtcc aatatgatca tgtgagaata ctaaaattcc taacgatgat atgttttcag 24660
ctagttcgtc ataacgtcca gaatgtttac cagctccatg acttatgaat actaatgcct 24720
taggatatgt aatcattgtc cagattgaac atacagtttg cactcatgat tcacgttata 24780
taactatcaa tattaacagt tcgtttgatg atcatattat ttttatgttt tattgataat 24840
tgtaaaaaca tacaattaaa tcaatataga ggaaggagac ggctactgtc ttttgtgaga 24900
tagtcatggc gactaaatta gattatgagg atgctgtttt ttactttgtg gatgatgata 24960
aaatatgtag tcgcgactcc atcatcgatc taatagatga atatattacg tggagaaatc 25020
atgttatagt gtttaacaaa gatattacca gttgtggaag actgtacaag gaattgatga 25080
agttcgatga tgtcgctata cggtactatg gtattgataa aattaatgag attgtcgaag 25140
ctatgagcga aggagaccac tacatcaatt ttacaaaagt ccatgatcag gaaagtttat 25200
tcgctaccat aggaatatgt gctaaaatca ctgaacattg gggatacaaa aagatttcag 25260
aatctagatt ccaatcattg ggaaacatta cagatctgat gaccgacgat aatataaaca 25320
tcttgatact ttttctagaa aaaaaattga attgatgata taggggtctt cataacgcat 25380
aattattacg ttagcattct atatccgtgt taaaaaaaat tatcctatca tgtatttgag 25440
agttttatat gtagcaaaca tgatagctgt gatgccaata agctttagat attcacgcgt 25500
gctagtgtta gggatggtat tatctggtgg tgaaatgtcc gttatataat ctacaaaaca 25560
atcatcgcat atagtatgcg atagtagagt aaacattttt atagttttta ctggattcat 25620
acatcgtcta cccaattcgg ttatgaatga aattgtcgcc aatcttacac ccaacccctt 25680
gttatccatt agtatagtat taacttcgtt atttatgtca taaactgtaa atgattttgt 25740
agatgccata tcatacatga tattcatgtc cctattataa tcattactaa ctttatcaca 25800
atatatgttg ataatatcta tatatgatct agtctttgtg ggcaactgtc tatacaagtc 25860
gtctaaacgt tgtttactca tatagtatcg aacagccatc attacatggt cccgttccgt 25920
tgatagataa tcgagtatgt tagtggactt gtcaaatcta tataccatat tttctggaag 25980
tggatataca tagtcgtgat caacattatt gctagcctca tcttctatat cctgtactat 26040
accatctaca taatctacga tattattaca cataaacatc gacaacatac tattgtttat 26100
tatctaagtc ctgttgatcc aaacccttga tctcctctat ttgtactatc tagagattgt 26160
acttcttcca gttctggata atatatacgt tgatagatta gctgagctat tctatctcca 26220
gtatttacat taaacgtaca ttttccatta ttaataagaa tgactcctat gtttccccta 26280
taatcttcgt ctattacacc acctcctata tcaatgcctt ttagtgacag accagaccta 26340
ggagctattc taccatagca aatcttaggc atggacatac taatatctgt cttaattaac 26400
tgtctttctc ctggagggat agtataatcg taagcgctat acaaatcata tccggcagca 26460
cccggcgatt gcctagtagg agatttagct ctgttagttt ccttaacaaa tctaactggt 26520
gagttaatat tcatgttgaa cataaaacta atattttatt tcaaaattat ttaccatccc 26580
atatattcca tgaataagtg tgatgattgt acacttctat agtatctata tacgattcac 26640
gataaaatcc tcctatcaat agcagtttat tatccactat gatcaattct ggattatccc 26700
tcggataaat aggatcatct atcagagtcc atgtattgct ggattcacaa taaaattccg 26760
catttctacc aaccaagaat aaccttctac cgaacactaa cgcgcatgat ttataatgag 26820
gataataagt ggatggtcca aactgccact gatcatgatt gggtagcaaa tattctgtag 26880
ttgtatcagt ttcagaatgt cctcccatta cgtatataac attgtttatg gatgccactg 26940
ctggattaca tctaggtttc agaagactcg gcatattaac ccaagcagca tccccgtgga 27000
accaacgctc aacagatgtg ggatttggta gacctcctac tacgtataat ttattgttag 27060
cgggtatccc gctagcatac agtctggggc tattcatcgg aggaattgga atccaattgt 27120
ttgatatata atttacagct atagcattgt tatgtatttc attgttcatc catccaccga 27180
tgagatatac tacttctcca acatgagtac ttgtacacat atggaatata tctataattt 27240
gatccatgtt cataggatac tctatgaatg gatacttgta tgatttgcgt ggttgtttat 27300
cacaatgaaa tattttggta cagtctagta tccattttac attatttata cctctgggag 27360
aaagataatt tgacctgatt acatttttga taaggagtag cagatttcct aatttatttc 27420
ttcgctttat ataccactta atgacaaaat cctcatctgg aacatttagt tcatcgcttt 27480
ctagaataag tttcatagat agataatcaa aattgtctat gatgtcatct tccagttcca 27540
aaaagtgttt ggcaataaag tttttagtat gacataagag attggatagt ccgtattcta 27600
tacccatcat gtaacactcg acacaatatt cctttctaaa atctcgtagg ataaagttta 27660
tacaagtgta gatgataaat tctacagagg ttaatataga agcacgtaat aaattgacga 27720
cgttatgact atctatatat acctttccag tatatgagta aataactata gaagttagac 27780
tgtgaatgtc aaggtctaga caaaccctcg taactggatc tttatttttc gtgtattttt 27840
gacgtaaatg tgtgcgaaag taaggagata actttttcaa tatcgtagaa ttgactatta 27900
tattgcctcc tatggcatca ataattgttt tgaatttctt agtcatagac aatgctaata 27960
tattcttaca gtacacagta ttgacaaata tcggcattta tgtttcttta aaagtcaaca 28020
tctaaagaaa aatgattatc ttcttgagac ataactccca ttttttggta ttcacccaca 28080
cgtttttcga aaaaattagt tttaccttct aatgatatat tttccatgaa atcaaacgga 28140
ttggtaacat tataaatttt tttaaatccc aattcagaaa tcaatctatc cgcgacgaat 28200
tctatatatg ttttcatcat ttcacaattc attcctataa gtttaactgg aagagccgca 28260
gtaagaaatt cttgttcaat ggataccgca tctgttataa tagatctaac ggtttcttca 28320
ctcggtggat gcaataaatg tttaaacatc aaacatgcga agtcgcagtg tagaccctcg 28380
tctctactaa tcaattcgtt ggaaaacgtg agtccgggca ttaggccacg ctttttaagc 28440
caaaatatgg aagcgaatga tccggaaaag aagattcctt ctactgcagc aaaggcaata 28500
agtctctctc cataaccggc gctgtcatgt atccactttt gagcccaatc ggccttcttt 28560
tttacacaag gcatcgtttc tatggcatta aagagatagt ttttttcatt actatcttta 28620
acataagtat cgatcaaaag actatacatt tccgaatgaa tgttttcaat ggccatctga 28680
aatccgtaga aacatctagc ctcggtaatc tgtacttctg tacaaaatcg ttccgccaaa 28740
ttttcattca ctattccgtc actggctgca aaaaacgcca atacatgttt tataaaatat 28800
ttttcgtctg gtgttagttt attccaatca ttgatatctt tagatatatc tacttcttcc 28860
actgtccaaa atgatgcctc tgccttttta tacatgttcc agatgtcatg atattggatt 28920
gggaaaataa caaatctatt tggatttggt gcaaggatgg gttccataac taaattaaca 28980
ataacaataa attttttttc agttatctat atgcctgtac ttggatcttt tgtacatcga 29040
tatcgccgca atcactacaa taattacaag tattattgat agcattgtta ttagtactat 29100
cataattaaa ttatcgttat tatcattttg taattgtgac atcatactag ataaatcgtt 29160
tgcgagattg ttgtgggaag cgggcatgga ggatgaatta tcgttattat tatttaaagc 29220
ctcccattcg gattcacaaa tatggcgcgc gttcaacatt ttatggaaac agataacaag 29280
aaaactcgtc atcgttcaaa tttttaacga tagtaaaccg attaaacgtc gagctaattt 29340
ctaacgctag cgactctgtt ggatatgggt ttccagatat atatcttttc agttccccta 29400
cgtatctata atcatctgta ggaaatggaa gatatttcca tttatctact gttcctaata 29460
tcatatgtgg tggtgtagta gaaccattaa gcgcgaaaga tgttatttcg catcgtattt 29520
taacttcgca ataatttctg gttagataac gcactctacc agtcaagtca atgatattag 29580
cctttacaga tatattcata gtagtcgtaa cgatgactcc atcttttaga tgcgatactc 29640
ctttgtatgt accagaatct tcgtacctca aactcgatat atttaaacaa gttaatgaga 29700
tattaacgcg ttttatgaat gatgatatat aaccagaagt tttatcctcg gtggctagcg 29760
ctataacctt atcattataa taccaactag tgtgattaat atgtgacacg ttagtgtggg 29820
tacaaatatg tacattatcg tctacgtcgt attcgataca tccgcataca gccaacaaat 29880
ataaaatgac aaatactcta acgccgttcg tacccatctt gatgcggttt aataaatgtt 29940
ttgatttcaa tttattgtaa aaaaagattc ggttttatac tgttcgatat tctcattgct 30000
tatattttca tctatcatct ccacacagtc aaatccgtgg ttagcatgca cctcatcaac 30060
cggtaaaaga ctatcggact cttctatcat tataactcta gaatatttaa tttggtcatt 30120
attaatcaag tcaattatct tatttttaac aaacgtgagt attttactca ttttttataa 30180
aaacttttag aaatatacag actctatcgt gtgtctatat cttcttttta tatccaatgt 30240
atttatgtct gatttttctt catttatcat atataatggt ccaaattcta cacgtgcttc 30300
ggattcatcc agatcattaa ggttcttata attgtaacat ccttctcttc cctcttctac 30360
atcttccttc ttattcttat tcttagcgtc acagaatcta ccacagcagg atcccatgac 30420
gagcgtcata ttaaactaat ccattttcaa ttataatata cgattagtaa tgaccattaa 30480
aataaaaata ttcttcataa ccggcaagaa agtgaaaagt tcacattgaa actatgtcag 30540
tagtatacat catgaaatga tgatatatat atactctatt ttggtggagg attatatgat 30600
ataattcgtg gataatcatt cttaagacac atttcttcat tcgtaaatct tttcacgtta 30660
aatgagtgtc catattttgc aatttcttca tatgatggcg gtgtacgtgg acgaggctgc 30720
tcctgttctt gttgtagtcg ccgactgtcg tgtctgcgtt tagatccctc cattatcgcg 30780
attgcgtaga tggagtacta ttttatacct tgtaattaaa tttttttatt aattaaacgt 30840
ataaaaacgt tccgtatctg tatttaagag ccagatttcg tctaatagaa caaatagcta 30900
cagtaaaaat aactagaata attgctacac ccactagaaa ccacggatcg taatacggca 30960
atcggttttc gataataggt ggaacgtata ttttatttaa ggacttaaca attgtctgta 31020
aaccacaatt tgcttccgcg gatcctgtat taactatctg taaaagcata tgttgaccgg 31080
gcggagccga acattctccg atatccaatt tctgtatatc tataatatta ttaacctccg 31140
catacgcatt acagttcttt tctagcttgg ataccgcact aggtacatcg tctagatcta 31200
ttcctatttc ctcagcgata gctcttctat ccttttccgg aagcaatgaa atcacttcaa 31260
taaatgattc aaccatgagt gtgaaactaa gtcgagaatt actcatgcat ttgttagtta 31320
ttcggagcgc gcaattttta aactgtccta taacctctcc tatatgaata gcacaagtga 31380
cattagtagg gatagaatgt tgagctaatt tttgtaaata actatctata aaaagattat 31440
acaaagtttt aaactcttta gtttccgcca tttatccagt ctgagaaaat gtctctcata 31500
ataaattttt ccaagaaact aattgggtga agaatggaaa cctttaatct atatttatca 31560
cagtctgttt tggtacacat gatgaattct tccaatgccg tactaaattc gatatctttt 31620
tcgatttctg gatatgtttt taataaagta tgaacaaaga aatggaaatc gtaataccag 31680
ttatgtttaa ctttgaaatt gttttttatt ttcttgttaa tgattccagc cacttgggaa 31740
aagtcaaagt cgtttaatgc cgatttaata cgttcattaa aaacaaactt tttatccttt 31800
agatgaatta ttattggttc attggaatca aaaagtaaga tattatcggg tttaagatct 31860
gcgtgtaaaa agttgtcgca gcatggtagt tcgtaaattt taatgtataa cagagccatc 31920
tgtaaaaaga taaactttat gtattgtacc aaagatttaa atcctaattt gatagctagc 31980
tcggtatcta ctttatctgc cgaatacagt gctaggggaa aaattataat atttcctctt 32040
tcgtattcgt agttagttct cttttcatgt tcgaaaaagt gaaacatgcg gttaaaatag 32100
tttataacat taatattact gttaataact gccggataaa agtgggatag taatttcacg 32160
aatttgatac tgtcctttct ctcgttaaac gcctttaaaa aaactttaga agaatatctc 32220
aatgatagtt cctgaccatc catagtttgt atcaataata gcaacatatg aagaacacgt 32280
ttatacagag tatgtaaaaa tgttaattta tagtttaatc ccatggccca cgcacacacg 32340
attaattttt tttcatctcc ctttagattg ttgtatagaa atttgggtac tgtgaactcc 32400
gccgtagttt ccatgggact atataatttt gtggcctcga atacaaattt tactacatag 32460
ttatctatct taaagactat accatatcct cctgtagata tgtgataaaa atcgtcgttt 32520
ataggataaa atcgtttatc cttttgttgg aaaaaggatg aattaatgta atcattctct 32580
tctatcttta gtagtgtttc cttattaaaa ttcttaaaat aatttaacaa tctaactgat 32640
ggagcccaat tttggtgtaa atctaattgg gacattatat tgttaaaata caaacagtct 32700
cctaatataa cagtatctga taatctatgg ggagacatcc attgatattc aggggatgaa 32760
tcattggcaa cacccattta ttgtacaaaa agccccaatt tacaaacgaa agtccaggtt 32820
tgatagagac aaactattaa ctattttgtc tctgttttta atttctttgg taatgaaatt 32880
attcacaata tcagtatctt ctttatctac cagagatttt actaacttga taaccttggc 32940
tgtctcattc aatagggtag taatatttgt atgtgtgata ttgatatctt ttagaagtga 33000
ttctttgatg gtgccagcat acgaattaca ataatgcaga aactcggtta acatgcagga 33060
attatagtaa gccaattcca attgttgcct gtgttgtatt agagtgtcaa tatgagcaat 33120
ggtgtccttg cgtttctctg atagaatgcg agcagcgatt ttggcgttat catttgacga 33180
tatttctgga atgacgaatc ctgtttctac taactttttg gtaggacaaa gtgaaacaat 33240
caagaagata gcttctcctc ctatttgtgg aagaaattga actcctctag atgatctcct 33300
tgacagatat tggaccgaat tacagaagta cctggaatgt aaagccctga aaccccctca 33360
ttttttaagc agattgttgc cgtaaatcct gcactatgcc caagatagag agctcctttg 33420
gtgaatccat ctctatgttt cagtttaacc aagaaacagt cagctggtct aaaatttcca 33480
tctctatcta atacagcatc taacttgatg tcaggaacta tgaccggtta tgttatatgt 33540
aacattgagt aaatccttaa gttcataatc atcactgtca tcagttatgt acgatccaaa 33600
caatgtttct actggcatag tggatacgaa gatgctatcc atcagaatgt ttccctgatt 33660
agtattttct atatagctat tcttctttaa acgattttcc aaatcagtaa ctatgttcat 33720
ttttttagga gtaggacgcc tagccagtat ggaagaggat tttctagatc ctctcttcaa 33780
catctttgat ctcaatggaa tgcaaaaccc catagtgtaa caaccaacga taaaaataat 33840
attgtttttc actttttata attttaccat ctgactcatg gattcattaa tatctttata 33900
agagctacta acgtataatt ctttataact gaactgagat atatacaccg gatctatggt 33960
ttccataatt gagtaaatga atgctcggca ataactaatg gcaaatgtat aaaacaacga 34020
aattatacta gagttgttaa agttaatatt ttctatgagc tgttccaata aattatttgt 34080
tgtaactgcg ttcaagtcat aaatcatctt gatactatcc agtaaaccgt ttttaagttc 34140
tggaatatta ttatcccatt gtaaagcccc taattcgact atcgaatatc ctgctctgat 34200
agcagtttca atatcgacgg acgtcaatac tgtaataaag gtggtagtat tgtcatcatc 34260
gtgataaact actggaatat ggtcgttagt aggtacggta actttacaca acgcgatata 34320
taactttcct tttgtaccat ttttaacgta gttgggacgt cctgcagggt attgttttga 34380
agaaatgata tcgagaacag atttgatacg atatttgttg gattcctgat tatttactat 34440
aatataatct agacagatag atgattcgat aaatagagaa ggtatatcgt tggtaggata 34500
atacatcccc attccagtat tctcggatac tctattaatg acactagtta agaacatgtc 34560
ttctattcta gaaaacgaaa acatcctaca tggactcatt aaaacttcta acgctcctga 34620
ttgtgtctcg aatgcctcgt acaaggattt caaggatgcc atagattctt tgaccaacga 34680
tttagaattg cgtttagcat ctgatttttt tattaaatcg aatggtcggc tctctggttt 34740
gctaccccaa tgataacaat agtcttgtaa agataaaccg caagaaaatt tatacgcatc 34800
catccaaata accctagcac catcggatga tattaatgta ttattataga ttttccatcc 34860
acagttattg ggccagtata ctgttagcaa cggtatatcg aatagattac tcatgtaacc 34920
tactagaatg atagttcgtg tactagtcat aatatcttta atccaatcta agaaatttaa 34980
aattagattt tttacactgt taaagttaac aaaggtatta cccggatacg tggatatcat 35040
atatggtatt ggtccattat cagtaatagc tccataaact gatacggcga tggtttttat 35100
atgtgtttga tctaacgagg aagaaattcg cgcccacaat tcatctctag atatgtattt 35160
aatatcaaac ggtaacacat caatttcggg acgcgtatat gtttctaaat ttttaatcca 35220
aatataatga tgacctatat gccctattat catactgtca actatagtac acctagagaa 35280
cttacgatac atctgtttcc tataatcgtt aaattttaca aatctataac atgctaaacc 35340
ttttgacgac aaccattcat taatttctga tatggaatct gtattctcaa taccgtatcg 35400
ttctaaagcc agtgctatat ctccctgttc gtgagaacgc tttcgtataa tatcgatcaa 35460
cggataatct gaagtttttg gagaataata tgactcatga tctatttcgt ccataaacaa 35520
tctagacata ggaattggag gcgatgatct taattttgtg caatgagtcg tcaatcctat 35580
aacttctaat attgtaatat tcatcatcga cataacacta tctatgttat catcgtatat 35640
tagtatacca tgaccttctt catttcgtgc caaaatgata tacagtctta aatagttacg 35700
caatatctca atagtttcat aattgttagc tgttttcatc aaggtttgta tcctgtttaa 35760
catgatggcg ttctatacgt ttctattttt taaattttta acgatttact gtggctagat 35820
acccaatctc tctcaaatat ttttttagcc tcgcttacaa gctgtttatc tatactatta 35880
aaactgacga atccgtgatt ttggtaatgg gttccgtcga aatttgccga agtgatatga 35940
acatattcgt cgtcgactat caacaatttt gtattattct gaatagtgaa aaccttcaca 36000
gatagatcat tttgaacaca caacgcgtct agacttctgg cggttgccat agaatatacg 36060
tcgttcttat cccaattacc aactagaagt ctgatcttaa ctcctctatt aatggctgct 36120
tctataatgg agttgtaaat gtcgggccaa tagtagctat taccgtcgac acgtgtagtg 36180
ggaactatgg ccaaatgttc aatatctata ctagtcttag ccgacttgag tttatcaata 36240
actacatcag tgtctagatc tctagaatat cccaataggt gttccggaga atcagtaaag 36300
aacactccac ctataggatt cttaatatga tacgcagtgc taactggcag acaacaagcc 36360
gcagagcata aattcaacca tgaatttttt gcgctattaa aggctttaaa agtatcaaat 36420
cttctacgaa gatctgtggc cagcggggga taatcagaat atacacctaa cgttttaatc 36480
gtatgtatag atcctccagt aaatgacgcg tttcctacat aacatctttc attatctgac 36540
acccaaaaac aaccgagtag tagtcccaca ttattttttt tatctatatt aacggttata 36600
aaatttatat ccgggcagtg actttgtagc tctcccagat ttcttttccc tcgttcatct 36660
agcaaaacta ttattttaat ccctttttca gatgcctctt ttagtttatc aaaaataagc 36720
gctcccctag tcgtactcag aggattacaa caaaaagatg ctatgtatat atatttctta 36780
gctagagtga taatttcgtt aaaacattca aatgttgtta aatgatcgga tctaaaatcc 36840
atattttctg gtagtgtttc taccagccta cattttgctc ccgcaggtac cggtgcaaat 36900
ggccacattt agttaacata aaaacttata catcctgttc tatcaacgat tctagaatat 36960
catcggctat atcgctaaaa ttttcatcaa agtcgacatc acaacctaac tcagtcaata 37020
tattaagaag ttccatgatg tcatcttcgt ctatttctat atccgtatcc attgtagatt 37080
gttgaccgat tatcgagttt aaatcattac taatactcaa tccttcagaa tacaatctgt 37140
gtttcattgt aaatttatag gcggtgtatt taagttggta gattttcaat tatgtatcaa 37200
tatagcaaca gtagttcttg ctcctccttg attctagcat cctcttcatt attttcttct 37260
acgtacataa acatgtccaa tacgttagac aacacaccga cgatggcggc cgccacagac 37320
acgaatatga ctaaaccgat gaccatttaa aaacccctct ctagctttca cttaaactgt 37380
atcgattatt cttttagaac atgtataata taaaaacatt attctatttc gaatttaggc 37440
ttccaaaaat ttttcatccg taaaccgata ataatatata tagacttgtt aatagtcgga 37500
ataaatagat taatgcttaa actatcatca tctccacgat tagagataca atatttacat 37560
tttttttgct gtttcgaaac tttatcaata cacgttaata caaacccagg aaggagatat 37620
tgaaactgag gctgttgaaa atgaaacggt gaatacaata attcagataa tgtaaaatca 37680
tgattccgta ttctgatgat attagaactg ctaatggatg tcgatggtat gtatctagga 37740
gtatctattt taacaaagca tcgatttgct aatatacaat tatcattttg attaattgtt 37800
attttattca tattcttaaa aggtttcata tttatcaatt cttctacatt aaaaatttcc 37860
atttttaatt tatgtagccc cgcaatactc ctcattacgt ttcatttttt gtctataata 37920
tccattttgt tcatctcggt acatagatta tccaattgag aagcgcattt agtagttttg 37980
tacattttaa gtttattgac gaatcgtcga aaactagtta tagttaacat tttattattt 38040
gataccctga tattaatacc cctgccgtta ctattattta taactgatgt aatccacgta 38100
acattggaat taactatcga tagtaatgca tcgacgcttc caaaattgtc tattataaac 38160
tcaccgataa tttttttatt acatgttttc atattcatta ggattattaa atctttaatc 38220
ttactacgat tgtatgcgtt gatattgcaa gacgtcattc taaaagacgg aggatctcca 38280
tcaaatgcca gacaatcacg tacaaagtac atggaaatag gttttgttct attgcgcatc 38340
atagatttat atagaacacc cgtagaaata ctaatttgtt ttactctata aaatactaat 38400
gcatctattt catcgttttg tataacgtct ttccaagtgt caaattccaa atttttttca 38460
ttgatagtac caaattcttc tatctcttta actacttgca tagataggta attacagtga 38520
tgcctacatg ccgttttttg aaactgaata gatgcgtcta gaagcgatgc tacgctagtc 38580
acaatcacca ctttcatatt tagaatatat atatgtaaaa atatagtaga atttcatttt 38640
gttttttttc tatgctataa atgaattctc attttgcatc tgctcatact ccgttttata 38700
tcaataccaa agaaggaaga tatctggttc taaaagccgt taaagtatgc gatgttagaa 38760
ctgtagaatg cgaaggaagt aaagcttcct gcgtactcaa agtagataaa ccctcatcac 38820
ccgcgtgtga gagaagacct tcgtcccctt ccagatgcga gagaatgaat aacccaggaa 38880
aacaagttcc gtttatgagg acggacatgc tacaaaatat gttcgcggct aatcgcgata 38940
atgtagcttc tagacttttg tcctaaaata caattatatc cttttcgata ttaataaatc 39000
cgtgtcgtcc aggtttttta tctctttcag tatgtgaata gataggtatt ttatctctat 39060
tcatcatcga atttaagaga tccgataaac attgtttgta ttctccagat gtcagcatct 39120
gatacaacaa tatatgtgca cataaacctc tggcacttat ttcatgtacc ttccccttat 39180
cactaaggag aatagtattt gagaaatatg tatacatgat attatcatga attagatata 39240
cagaatttgt aacactctcg aaatcacacg atgtgtcggc gttaagatct aatatatcac 39300
tcgataacac attttcatct agatacacta gacatttttt aaagctaaaa tagtctttag 39360
tagtaacagt aactatgcga ttattttcat cgatgataca tttcatcggc atattattac 39420
gcttaccatc aaagactata ccatgtgtat atctaacgta ttctagcatg gttgccatac 39480
gcgcattaaa cttttcagga tctttggata gatcttccaa tctatctatt tgagaaaaca 39540
tttttatcat gttcaatagt tgaaacgtcg gatccactat atagatatta tctataaaga 39600
ttttaggaac tacgttcatg gtatcctggc gaatattaaa actatcaatg atatgattat 39660
cgttttcatc ttttatcacc atatagtttc taagatatgg gattttactt aatataatat 39720
tatttcccgt aataaatttt attagaaatg ccaaatctat aagaaaagtc ctcgaattag 39780
tttgaagaat atctatatcg ccgtaccgta tatttggatt aattagatat agagaatatg 39840
atccgtaaca tatacaactt ttattatggc gtctaagata ttcttccatc aacttattaa 39900
catttttgac tagggaagat acattatgac gtcccattac ttttgccttg tctattactg 39960
cgacgttcat agaatttagc atatctcttg ccaattcttc cattgatgtt acattataag 40020
aaattttaga tgaaattaca tttggagctt taatagtaag aactcctaat atgtccgtgt 40080
atgtggtcac taatacagat tgtagttcta taatcgtaaa taatttacct atattatatg 40140
tttgagtctg tttagaaaag tagctaagta tacgatcttt tatttctgat gcagatgtat 40200
caacatcgga aaaaaatctt tttttattct tttttactaa agatacaaat atgtctttgt 40260
taaaaacagt tattttctga atatttctag cttgtaattt taacatatga tattcgttca 40320
cactaggtac tctgcctaaa taggtttcta taatctttaa tgtaatatta ggaaaagtat 40380
tctgatcagg attcctattc attttgagga tttaaaactc tgattattgt ctaatatggt 40440
ctcaacacaa actttttcac agagcgatag agtttttgat aactcgtttt tcttaagaaa 40500
tataaaacta ctgtctccag agctcgctct atcttttatt ttatttaatt cgatacaaac 40560
tcctgatact ggttcagaaa gtaattcatt aattttcagt cctttataga agatatttaa 40620
tatagataat acaaaatctt cagtttttga tatcgatctg attgatccta gaactagata 40680
tattaataac gtgctcatta ggcagtttat ggcagcttga taattagata tagtatattc 40740
cagttcatat ttattagata ccgcattgcc cagattttga tattctatga attcctctga 40800
aaataaatcc aaaataacta gacattctat tttttgtgga ttagtgtact ctcttccctc 40860
tatcatgttc actactggtg tccacgatga taaatatcta gagggaatat aatatagtcc 40920
ataggatgcc aatctagcaa tgtcgaataa ctgtaatttt attcttcgct cttcattatg 40980
aattgattct tgaggtataa acctaacaca aattatatta ttagactttt cgtatgtaat 41040
gtctttcatg ttataagttt ttaatcctgg aatagaatct attttaatga ggcttttaaa 41100
cgcagagttc tccaacgagt caaagcataa tactctgttg gttttcttat atacgatgtt 41160
acgattttct tctttgaatg gaataggttt ttgaattagt ttataattac aacataatag 41220
ataaggaagt gtgcaaatag tacgcggaaa aaacataata gctcccctgt tttcatccat 41280
ggttttaagt aaatgatcac tggcttcttt agtcaatgga tattcgaaca ttaaccgttt 41340
catcatcatt ggacagaatc catatttctt aatgtaaaga gtgatcaaat cattgtgttt 41400
attgtaccat cttgttgtaa atgtgtattc ggttatcgga tctgctcctt tttctattaa 41460
agtatcgatg tcgatctcgt ctaagaattc aactatatcg acatatttca tttgtataca 41520
cataaccatt actaacgtag aatgtatagg aagagatgta acgggaacag ggtttgttga 41580
ttcgcaaact attctaatac ataattcttc tgttaatacg tcttgcacgt aatctattat 41640
agatgccaag atatctatat aattattttg taagatgatg ttaactatgt gatctatata 41700
agtagtgtaa taattcatgt atttcgatat atgttccaac tctgtctttg tgatgtctag 41760
tttcgtaata tctatagcat cctcaaaaaa tatattcgca tatattccca agtcttcagt 41820
tctatcttct aaaaaatctt caacgtatgg aatataataa tctattttac ctcttctgat 41880
atcattaatg atatagtttt tgacactatc ttctgtcaat tgattcttat tcactatatc 41940
taagaaacgg atagcgtccc taggacgaac tactgccatt aatatctcta ttatagcttc 42000
tggacataat tcatctatta taccagaatt aatgggaact attccgtatc tatctaacat 42060
agttttaaga aagtcagaat ctaagacctg atgttcatat attggttcat acatgaaatg 42120
atctctattg atgatagtga ctatttcatt ctctgaaaat tggtaactca ttctatatat 42180
gctttccttg ttgatgaagg atagaatata ctcaatagaa tttgtaccaa caaactgttc 42240
tcttatgaat cgtatatcat catctgaaat aatcatgtaa ggcatacatt taacaattag 42300
agacttgtct cctgttatca atatactatt cttgtgataa tttatgtgtg aggcaaattt 42360
gtccacgttc tttaattttg ttatagtaga tatcaaatcc aatggagcta cagttcttgg 42420
cttaaacaga tatagttttt ctggaacgaa ttctacaaca ttattataaa ggactttggg 42480
tagataagtg ggatgaaatc ctattttaat taatgcgata gccttgtcct cgtgcagata 42540
tccaaacgct tttgtgatag tatggcattc attgtctaga aacgctctac gaatatctgt 42600
gacagatatc atctttagag aatatactag tcgcgttaat agtactacaa tttgtatttt 42660
ttaatctatc tcaataaaaa aattaatatg tatgattcaa tgtataacta aactactaac 42720
tgttattgat aactagaatc agaatctaat gatgacgtaa ccaagaagtt tatctactgc 42780
caatttagct gcattatttt tagcatctcg tttagatttt ccatctgcct tatcgaatac 42840
tcttccgtcg atatctacac aggcataaaa tgtaggagag ttactaggcc ccactgattc 42900
aatacgaaaa gaccaatctc tcttagttat ttggcagtac tcattaataa tggtgacagg 42960
gttagcatct ttccaatcaa taattttttt agccggaata acatcatcaa aagacttatg 43020
atcctctctc attgattttt cgcgggatac atcatctatt atggcgtcag ccataacatc 43080
agcatccggc ttatccgcct ccgttgtcat aaaccaacga ggaggaatat cgtcggagct 43140
gtacaccata gcactacgtt gaagatcgta cagagcttta ttaacttctc gcttctccat 43200
attaagttgt ctagttagtt gtgcagcagt agctccttcg attccaatgt ttttaatagc 43260
cgcacacaca atctctgcgt cagaacgctc gtcaatatag atcttagaca tttttagaga 43320
gaactaacac aaccagcaat aaaactaatt tattttatca tttttttatt catcatcctc 43380
tggtggttcg tcgtttctat cgaatgtgga tctgattaac ccgtcatcta taggtgatgc 43440
tggttctgga gattctggag gagatggatt attatctgga agaatctctg ttatttcctt 43500
gttttcatgt atcgattgcg ttgtaacatt aagattgcga aatgctctaa atttgggagg 43560
cttaaagtgt tgtttgcaat ctctacacgc atgtctaact agtggaggtt cgtcagcggc 43620
tctagtttga atcatcatcg gcgtagtatt cctactttta cagttaggac acggtgtatt 43680
gtatttctcg tcgagaacgt taaaataatc gttgtaactc acatccttta ttttatctat 43740
attgtattct actcctttct taatgcattt tataccgaat aagagatagc gaaggaattc 43800
tttttcggtg ccgctagtac ccttaatcat atcacatagt gttttatatt ccaaatttgt 43860
ggcaatagac ggtttatttc tatacgatag tttgtttctg gaatcctttg agtattctat 43920
accaatatta ttctttgatt cgaatttagt ttcttcgata ttagattttg tattacctat 43980
attcttgatg tagtactttg atgatttttc catggcccat tctattaagt cttccaagtt 44040
ggcatcatcc acatattgtg atagtaattc tcggatatca gtagcggcta ccgccattga 44100
tgtttgttca ttggatgagt aactactaat gtatacattt tccatttata acacttatgt 44160
attaactttg ttcatttata ttttttcatt attatgttga tattaacaaa agtgaatata 44220
tatgttaata attgtattgt ggttatacgg ctacaatttc ataatgagtg gaagtcagtg 44280
tccgatgatc aatgacgata gctttactct gaaaagaaag tatcaaatcg atagtgcgga 44340
gtcaacaata aaaatggata agaagaggat aaagtttcag aatagagcca aaatggtaaa 44400
agaaataaat cagacaataa gagcagcaca aactcattac gagacattga aactaggata 44460
cataaaattt aagagaatga ttaggactac tactctagaa gatatagcac catctattcc 44520
aaataatcag aaaacttata aactattctc ggacatttca gccatcggca aagcatcaca 44580
gaatccgagt aagatggtat atgctctgct gctttacatg tttcccaatt tgtttggaga 44640
tgatcataga ttcattcgtt atagaatgca tccaatgagt aaaatcaaac acaagatctt 44700
ctctcctttc aaacttaatc ttattagaat attagtggaa gaaagattct ataataatga 44760
atgcagatct aataaatgga gaataattgg aacacaagtt gataaaatgt tgatagctga 44820
atctgataaa tatacaatag atgcaaggta taacctaaaa cccatgtata gaatcaaggg 44880
aaaatctgaa gaagataccc tctttatcaa acagatggta gaacaatgtg tgacatccca 44940
ggaattggtg gaaaaagtgt tgaagatact gtttagagat ttgttcaaga gtggagaata 45000
caaagcgtac agatacgatg atgatgtaga aaatggattt attggattgg atacactaaa 45060
attaaacatt gttcatgata tagttgaacc atgtatgcct gttcgtaggc cagtggctaa 45120
gatactgtgt aaagaaatgg taaataaata ctttgagaat ccgctacata ttattggtaa 45180
aaatcttcaa gagtgcattg actttgttag tgaataggca tttcatcttt ctccaatact 45240
aattcaaatt gttaaattaa taatggatag tataaatagt tattagtgat aaaatagtaa 45300
aaataattat tagaataaga gtgtagtatc atagataact ctcttctata aaaatggatt 45360
ttattcgtag aaagtatctt atatacacag tagaaaataa tatagatttt ttaaaggatg 45420
atacattaag taaagtaaac aattttaccc tcaatcatgt actagctctc aagtatctag 45480
ttagcaattt tcctcaacac gttattacta aggatgtatt agctaatacc aatttttttg 45540
ttttcataca tatggtacga tgttgtaaag tgtacgaagc ggttttacga cacgcatttg 45600
atgcacccac gttgtacgtt aaagcattga ctaagaatta tttatcgttt agtaacgcaa 45660
tacaatcgta caaggaaacc gtgcataaac taacacaaga tgaaaaattt ttagaggttg 45720
ccgaatacat ggacgaatta ggagaactta taggcgtaaa ttatgactta gttcttaatc 45780
cattatttca cggaggggaa cccatcaaag atatggaaat cattttttta aaactgttta 45840
agaaaacaga cttcaaagtt gttaaaaaat taagtgttat aagattactt atttgggctt 45900
acctaagcaa gaaagataca ggcatagagt ttgcggataa tgatagacaa gatatataca 45960
ctctatttca acaaactggt agaatagtcc atagcaatct aacagaaacg tttagagatt 46020
atatctttcc cggagataag actagctatt gggtgtggtt aaacgaaagt atagctaatg 46080
atgcggatat tgttcttaat agacacgcca ttaccatgta tgataaaatt cttagttata 46140
tatactctga gataaaacaa ggacgcgtta ataaaaacat gcttaagtta gtttatatct 46200
ttgagcctga aaaagatatc agagaacttc tgctagaaat catatatgat attcctggag 46260
atatcctatc tattattgat gcaaaaaacg acgattggaa aaaatatttt attagttttt 46320
ataaagctaa ttttattaac ggtaatacat ttattagtga tagaacgttt aacgaggact 46380
tattcagagt tgttgttcaa atagatcccg aatatttcga taatgaacga attatgtctt 46440
tattctctac gagtgctgcg gacattaaac gatttgatga gttagatatt aataacagtt 46500
atatatctaa tataatttat gaggtgaacg atatcacatt agatacaatg gatgatatga 46560
agaagtgtca aatctttaac gaggatacgt cgtattatgt taaggaatac aatacatacc 46620
tgtttttgca cgagtcggat cccatggtca tagagaacgg aatactaaag aaactgtcat 46680
ctataaaatc caagagtaga cggctgaact tgtttagcaa aaacatttta aaatattatt 46740
tagacggaca attggctcgt ctaggtcttg tgttagatga ttataaagga gacttgttag 46800
ttaaaatgat aaaccatctt aagtctgtgg aggatgtatc cgcattcgtt cgattttcta 46860
cagataaaaa ccctagtatt cttccatcgc taatcaaaac tattttagct agttataata 46920
tttccatcat cgtcttattt caaaggtttt tgagagataa tctatatcat gtagaagaat 46980
tcttggataa aagcatccat ctaaccaaga cggataagaa atatatactt caattgataa 47040
gacacggtag atcatagaac agaccaaata tattattaat aatttgtata tacatagata 47100
taattatcac acatttttga taaatgggaa ctgctgcaac aattcagact cccaccaaat 47160
taatgaataa agaaaatgca gaaatgattt tggaaaaaat tgttgatcat atagttatgt 47220
atattagtga cgaatcaagt gattcagaaa ataatcctga atatattgat tttcgtaaca 47280
gatacgaaga ctatagatct ctcattataa aaagtgatca cgagtttgta aagctatgta 47340
aaaatcatgc agagaaaagt tctccagaaa cgcaacaaat gattatcaaa cacatatacg 47400
aacaatatct tattccagta tctgaagtac tattaaaacc tataatgtcc atgggtgaca 47460
taattacata taacggatgt aaagacaatg aatggatgct agaacaactc tctaccctaa 47520
actttaacaa tctccgcaca tggaactcat gtagcatagg caatgtaacg cgtctgtttt 47580
atacattttt tagttatctg atgaaagata aactaaatat ataagtataa tcccattcta 47640
atactttaac ctgatgtatt acctgcatct tattagaata ttaacctaac taaaagacat 47700
aacatagttg ataaaaagcg gtaggatata aatattatgg ctgccaccgt tccgcgtttt 47760
gacgacgtgt acaaaaatgc acaaagaaga attctagatc aagaaacatt ttttagtaga 47820
ggtctaagta gaccgttaat gaaaaacaca tatctatttg ataattacgc gtatggatgg 47880
ataccagaaa ctgcaatttg gagtagtaga tacgcaaact tagatgcaag tgactattat 47940
cccatttcgt tgggattact taaaaagttc gagtttctca tgtctctata taaaggtcct 48000
attcccgtat atgaagaaaa agtaaatact gaattcattg ctaatggatc gttctctggt 48060
agatacgtat catatcttcg aaagttttct gcccttccaa caaacgagtt tattagtttt 48120
ttgttactga cttccattcc aatctataat atcttgttct ggtttaaaaa tactcagttt 48180
gatattacta aacacacatt attcagatac gtctatacag ataatgccaa acacctggcg 48240
ttggctaggt atatgcatca aacaggagac tataagcctt tgtttagtcg tctcaaagag 48300
aattatatat ttaccggtcc cgttccaata agtatcaaag atatagatca ccctaatctt 48360
agtagagcaa gaagtccatc cgattatgag acattagcta atattagtac tatattgtac 48420
tttaccaagt atgatccggt attaatgttt ttattgtttt acgtacctgg gtattcaatt 48480
actacaaaaa ttactccagc cgtagaatat ctaatggata aactgaatct aacaaagagc 48540
gacgtacaac tgttgtaaat tattttatgc ttcgtaaaat gtaggttttg aaccaaacat 48600
tctttcaaag aatgagatgc ataaaacttt attatccaat agattgacta tttcggacgt 48660
caatcgttta aagtaaactt cgtaaaatat tctttgatca ctgccgagtt taaaacttct 48720
atcgataatt gtttcatatg ttttaatatt tacaagtttt ttggtccatg gtacattagc 48780
cggacaaata tatgcaaaat aatatcgttc tccaagttct atagtttctg gattattttt 48840
attatattca gtaaccaaat acatattagg gttatctgcg gatttataat ttgagtgatg 48900
cattcgactc aacataaata attctagagg agacgatcta ctatcaaatt cggatcgtaa 48960
atctgtttct aaagaacgga gaatatctat acatacctga ttagaattca tccgtccttc 49020
agacaacatc tcagacagtc tggtcttgta tgtcttaatc atattcttat gaaacttgga 49080
aacatctctt ctagtttcac tagtaccttt attaattctc tcaggtacag attttgaatt 49140
cgacgatgct gagtatttca tcgttgtata tttcttcttc gattgcataa tcagattctt 49200
atataccgcc tcaaactcta ttttaaaatt attaaacaat actctattat taatcagtcg 49260
ttctaactct ttcgctattt ctatagactt atcgacatct tgactgtcta tctctgtaaa 49320
cacggagtcg gtatctccat acacgctacg aaaacgaaat ctgtaatcta taggcaacga 49380
tgttttcaca atcggattaa tatctctatc gtccatataa aatggattac ttaatggatt 49440
ggcaaaccgt aacataccgt tagataactc tgctccattt agtaccgatt ctagatacaa 49500
gatcattcta cgtcctatgg atgtgcaact cttagccgaa gcgtatgagt atagagcact 49560
atttctaaat cccatcagac catatactga gttggctact atcttgtacg tatattgcat 49620
ggaatcatag atggcctttt cagttgaact ggtagcctgt tttagcatct ttttatatct 49680
ggctctctct gccaaaaatg ttcttaatag tctaggaatg gttccttcta tcgatctatc 49740
gaaaattgct atttcagaga tgaggttcgg tagtctaggt tcacaatgaa ccgtaatata 49800
tctaggaggt ggatatttct gaagcaagag ctgattattt atttcttctt ccaatctatt 49860
ggtactaaca acgacaccga ctaatgtttc cggagataga tttccaaaga tacacacatt 49920
aggatacaga ctgttataat caaagattaa tacattatta ctaaacattt tttgttttgg 49980
agcaaatacc ttaccgcctt cataaggaaa cttttgtttt gtttctgatc taactaagat 50040
agttttagtt tccaacaata gctttaacag tggacccttg atgactgtac tcgctctata 50100
ttcgaatacc atggattgag gaagcacata tgttgacgca cccgcgtctg tttttgtttc 50160
tactccataa tactcccaca aatactgaca caaacaagca tcatgaatac agtatctagc 50220
catatctaaa gctatgttta gattataatc cttatacatc tgagctaaat caacgtcatc 50280
ctttccgaaa gataatttat atgtatcatt aggtaaagta ggacatgata gtacgacttt 50340
aaatccattt tcccaaatat ctttacgaat tactttacat ataatatcct catcaacagt 50400
cacataatta cctgtggtta aaacctttgc aaatgcagcg gctttgcctt tcgcgtccgt 50460
agtatcgtca ccgatgaacg tcatttctct aactcctcta tttaatactt tacccatgca 50520
actgaacgcg ttcttggata tagaatccaa tttgtacgaa tccaattttt cagatttttg 50580
aatgaatgaa tatagatcga aaaatatagt tccattattg ttattaacgt gaaacgtagt 50640
attggccatg ccgcctactc ccttatgact agactgattt ctctcataaa tacagagatg 50700
tacagcttcc tttttgtccg gagatctaaa gataatcttc tctcctgtta ataactctag 50760
acgattagta atatatctca gatcaaagtt atgtccgtta aaggtaacga cgtagtcgaa 50820
cgttagttcc aacaattgtt tagctattcg taacaaaact atttcagaac atagaactag 50880
ttctcgttcg taatccattt ccattagtga ctgtatcctc aaacatcctc tatcgacggc 50940
ttcttgtatt tcctgttccg ttaacatctc ttcattaatg agcgtaaaca ataatcgttt 51000
accacttaaa tcgatataac agtaacttgt atgcgagatt gggttaataa atacagaagg 51060
aaacttctta tcgaagtgac actctatatc tagaaataag tacgatcttg ggatatcgaa 51120
tctaggtatt tttttagcga aacagttacg tggatcgtca caatgataac atccattgtt 51180
aatctttgtc aaatattgct cgtccaacga gtaacatccg tctggagata tcccgttaga 51240
aatataaaac caactaatat tgagaaattc atccatggtg gcattttgta tgctgcgttt 51300
ctttggctct tctatcaacc acatatctgc gacggagcat tttctatctt taatatctag 51360
attataactt attgtctcgt caatgtctat agttctcatc tttcccaacg gcctcgcatt 51420
aaatggagga ggagacaatg actgatatat ttcgtccgta actacgtaat aaaagtaatg 51480
aggaaatcgt ataaatacgg tctcgccatt tcgacatctg gatttcagat ataaaaatct 51540
gttttcaccg tgactttcaa accaattaat gcaccgaaca tccatttata gaatttagaa 51600
atatattttc atttaaatga atcccaaaca ttggggaaga gccgtatgga ccattatttt 51660
tatagtactt tcgcaagcgg gtttagacgg caacatagaa gcgtgtaaac gaaaactata 51720
tactatagtc agcactcttc catgtcctgc atgtagacgg cacgcgacta tcgctataga 51780
ggacaataat gtcatgtcta gcgatgatct gaattatatt tattattttt tcatcagatt 51840
atttaacaat ttggcatctg atcccaaata cgcgatcgat gtgacaaagg ttaacccttt 51900
ataaacttaa cccattataa aacttatgat tagtcacgac tgaaataacc gcgtgattat 51960
tttttggtat aattctacac ggcatggttt ctgtaactat gaattcaacc cccgttacat 52020
tagtgaaatc tttaacaaac agcaagggtt cgtcaaagac ataaaactca ttgtttacaa 52080
tcgaaataga ccccctatca cacttaaaat aaaaaatatc cttatccttt accaccaaat 52140
aaaattctga ttggtcaatg tgaatgtatt cacttaacag ttccacaaat ttatttatta 52200
actccgaggc acatacatcg tcggtatttt ttatggcaaa ctttactctt ccagcatccg 52260
tttctaaaaa aatattaacg agttccattt atatcatcca atattattga aatgacgttg 52320
atggacagat gatacaaata agaaggtacg gtacctttgt ccaccatctc ctccaattca 52380
tgctctattt tgtcattaac tttaatgtat gaaaacagta cgccacatgc ttccatgaca 52440
gtgtgtaaca ctttggatac aaaatgtttg acattagtat aattgtccaa gactgtcaat 52500
ctataataga tagtagctat aatatattct atgatggtat tgaagaagat gacaatcttg 52560
gcatattgat catttaacac agacatggta tcaacagata gcttgaatga aagagaatca 52620
gtaattggaa taagcgtctt ctcgatagag tgtccgtata ccaacatgtc tgatattttg 52680
atgtattcca ttaaattatt tagttttttc tttttattct cgttaaacag catttctgtc 52740
aacggacccc aacatcgttg accgattaag ttttgattga tttttccgtg taaggcgtat 52800
ctagtcagat cgtatagcct atccaataat ccatcatctg tgcgtagatc acatcgtaca 52860
ctttttaatt ctctatagaa gagcgacaga cagcaatttc tttattctct acagatgtaa 52920
gatacttgaa gacattccta tgatgatgca gaattttgga taacacggta ttgatggtat 52980
ctgttaccat aattcctttg atggctgata gtgtcagagc acaagatttc caatctttgt 53040
tttgatatct atatcagaca gcatggtgcg tctgacaaca caaggattaa gacggaaaga 53100
tgaaatgatt ctctcaacat cttcaatgga taccttgcta ttttttctgg cattatctat 53160
atgtgcgaga atatcctcta gagaatcagt atcctttttg atgatagtgg atctcaatga 53220
catgggacgt ctaaaccttc ttattctatc accagattgc atggtgattt gtcttctttc 53280
ttttatcata atgtaatctc taaattcatc ggcaaattgt ctatatctaa aatcataata 53340
tgagatgttt acctctacaa atatctgttc gtccaatgtt agagtatcta catcagtttt 53400
gtattccaaa ttaaacatgg caacggattt aattttatat tcctctatta agtcctcgtc 53460
gataataaca gaatgtagat aatcatttaa tccatcgtac atggttggaa gatgcttgtt 53520
gacaaaatct ttaattgtct tgatgaaggt gggactatat ctaacatctt gattaataaa 53580
atttataaca ttgtccatag gatactttgt aactagtttt atacacatct cttcatcggt 53640
aagtttagac agaatatcgt gaacaggtgg tatattatat tcatcagata tacgaagaac 53700
aatgtccaaa tctatattgt ttaatatatt atatagatgt agcgtagctc ctacaggaat 53760
atctttaact aagtcaatga tttcatcaac cgttagatct attttaaagt taatcatata 53820
ggcattgatt tttaaaaggt atgtagcctt gactacattc tcattaatta accattccaa 53880
gtcactgtgt gtaagaagat tatattctat cataagcttg actacatttg gtcccgatac 53940
cattaaagaa ttcttatgat ataaggaaac agattttagg tactcatcta ctctacaaga 54000
attttggaga gccttaacga tatcagtgac gtttattatt tcaggaggaa agaatctaac 54060
attgagaata tcggaattaa tagcttccag atacagtgat tttggcaata gtccgtgtaa 54120
tccataatcc agtaacacga gctggtgctt gctagacacc ttttcaatgt ttaatttttt 54180
tgaaataagc tttgataaag ccttcctcgc aaattccgga tacatgaaca tgtcggcgac 54240
atgattaagt attgtttttt cattattttc tcaacaagtt ctcaataccc caatagatga 54300
tagaatatca cccaatgcgt ccatgttgtc tatttccaac aggtcgctat atccaccaat 54360
agaagttttt ccaaaaaaga ttctaggaac agttctacca ccagtaattt gttcaaaata 54420
gtcacgcaat tcattttcgg gtttaaattc tttaatatcg acaatttcat acgctcctct 54480
tttgaaacta aacttattta gaatatccag tgcatttcta caaaaaggac atgtatactt 54540
gacaaaaatt gtcactttgt tattggccaa cctttgttgt acaaattcct cggccatttt 54600
aatatttaag tgatataaaa ctatctcgac ttatttaact ctttagtcga gatatatgga 54660
cgcagatagc tatatgatag ccaactacag aaggcaaacg ctataaaaaa cataattacg 54720
acgagcatat ttataaatat ttttattcag cattacttga tatagtaata ttaggcacag 54780
tcaaacattc aaccactctc gatacattaa ctctctcatt ttctttaaca aattctacaa 54840
tatcttcgta aaaagattct tgaaactttt tagaatatct atcgactcta gatgaaatag 54900
cgttcgtcaa catactatgt tttgtataca taaaggcgcc cattttaaca gtttctagtg 54960
acaaaatgct agcgatccta ggatccttta gaatcacata gattgacgat tcgtctctct 55020
tagtaactct agtaaaataa tcatacaatc tagtacgcga aataatatta tccttgactt 55080
gaggagatct aaacaatcta gttttgagaa catcgataag ttcatcggga atgacataca 55140
tactatcttt aatagaactc ttttcatcca gttgaatgga ttcgtcctta accaactgat 55200
taatgagatc ttctatttta tcattttcca gatgatatgt atgtccatta aagttaaatt 55260
gtgtagcgct tctttttagt ctagcagcca atactttaac atcactaata tcgatataca 55320
aaggagatga tttatctatg gtattaagaa ttcgtttttc gacatctgtc aaaaccaatt 55380
cctttttgcc tgtatcatcc agttttccat cctttgtaaa gaaattattt tctactagac 55440
tattaataag actgataagg attcctccat aattgcacaa tccaaacttt ttaacaaaac 55500
tagactttac aagatctaca ggaatgcgta attcaggttt cttagcttgt gattttttct 55560
tttgtggaca ttttcttgtg accaactcat ctaccatttc attgatttta gcagtgaaat 55620
aagctttcaa tgcacgggca ctgatactat tgaaaacgag ttgatcttca aattccgcca 55680
tttaagttca ccaaacaact tttaaataca aatatatcaa tagtagtaga ataagaacta 55740
taaaaaaaat aataattaac caataccaac cccaacaacc ggtattatta gttgatgtga 55800
ctgttttctc atcacttaga acagatttaa caatttctat aaagtctgtc aaatcatctt 55860
ccggagaccc cataaataca ccaaatatag cggcgtacaa cttatccatt tatacattga 55920
atattggctt ttctttatcg ctatcttcat catattcatc atcaatatca acaagtccca 55980
gattacgagc cagatcttct tctacatttt cagtcattga tacacgttca ctatctccag 56040
agagtccgat aacgttagcc accacttctc tatcaatgat tagtttcttg agtgcgaatg 56100
taatttttgt ttccgttccg gatctataga agacgatagg tgtgataatt gccttggcca 56160
attgtctttc tcttttactg agtgattcta gttcaccttc tatagatctg agaatggatg 56220
attctccagt cgaaacatat tctaccatgg atccgtttaa tttgttgatg aagatggatt 56280
catccttaaa tgttttctct gtaatagttt ccaccgaaag actatgcaaa gaatttggaa 56340
tgcgttcctt gtgcttaatg tttccataga cggcttctag aagttgatac aacataggac 56400
tagccgcggt aacttttatt tttagaaagt atccatcgct tctatcttgt ttagatttat 56460
ttttataaag tttagtctct ccttccaaca taataaaagt ggaagtcatt tgactagata 56520
aactatcagt aagttttata gagatagacg aacaattagc gtattgagaa gcatttagtg 56580
taacgtattc gatacatttt gcattagatt tactaatcga ttttgcatac tctataacac 56640
ccgcacaagt ctgtagagaa tcgctagatg cagtaggtct tggtgaagtt tcaactctct 56700
tcttgattac cttactcatg attaaaccta aataattgta ctttgtaata taatgatata 56760
tattttcact ttatctcatt tgagaataaa aatgtttttg tttaaccact gcatgatgta 56820
cagatttcgg aatcgcaaac caccagtggt tttattttat ccttgtccaa tgtgaattga 56880
atgggagcgg atgcgggttt cgtacgtaga tagtacattc ccgtttttag accgagactc 56940
catccgtaaa aatgcatact cgttagtttg gaataactcg gatctgctat atggatattc 57000
atagattgac tttgatcgat gaaggctccc ctgtctgcag ccatttttat gatcgtcttt 57060
tgtggaattt cccaaatagt tttataaact cgcttaatat cttctggaag gtttgtattc 57120
tgaatggatc caccatctgc cataatccta ttcttgatct catcattcca taattttctc 57180
tcggttaaaa ctctaaggag atgcggatta actacttgaa attctccaga caatactctc 57240
cgagtgtaaa tattactggt atacggttcc accgactcat tatttcccaa aatttgagca 57300
gttgatgcag tcggcatagg tgccaccaat aaactatttc taagaccgta tgttctgatt 57360
ttatctttta gaggttccca attccaaaga tccgacggta caacattcca aagatcatat 57420
tgtagaatac cgttactggc gtacgatcct acatatgtat cgtatggtcc ttccttctca 57480
gctagttcac aactcgcctc taatgcaccg taataaatgg tttcgaagat cttcttattt 57540
agatcttgtg cttccaggct atcaaatgga taatttaaga gaataaacgc gtccgctaat 57600
ccttgaacac caataccgat aggtctatgt ctcttattag agatttcagc ttctggaata 57660
ggataataat taatatctat aattttattg agatttctga caattacttt gaccacatcc 57720
ttcagtttga gaaaatcaaa tcgcccatct attacaaaca tgttcaaggc aacagatgcc 57780
agattacaaa cggctacctc attagcatcc gcatattgta ttatctcagt gcaaagatta 57840
ctacacttga tagttcctaa attttgttga ttactctttt tgttacacgc atccttataa 57900
agaatgaatg gagtaccagt ttcaatctga gattctataa tcgctttcca gacgactcga 57960
gcctttatta tagatttgta tctcctttct ctttcgtata gtgtatacaa tcgttcgaac 58020
tcgtctcccc aaacattgtc caatccagga cattcatccg gacacatcaa cgaccactct 58080
ccgtcatcct tcactcgttt cataaagaga tcaggaatcc aaagagctat aaatagatct 58140
ctggttctat gttcctcgtt tcctgtattc tttttaagat cgaggaacgc cataatatca 58200
gaatgccacg gttccaagta tatggccata actccaggcc gtttgtttcc tccctgatct 58260
atgtatctag cggtgttatt ataaactctc aacattggaa taataccgtt tgatatacca 58320
ttggtaccgg agatatagct tccactggca cgaatattac taattgatag acctattccc 58380
cctgccattt tagagattaa tgcgcatcgt tttaacgtgt catagatacc ctctatgcta 58440
tcatcgatca tgttaagtag aaaacagcta gacatttggt gacgactagt tcccgcatta 58500
aataaggtag gagaagcgtg cgtaaaccat ttttcagaaa gtagattgta cgtctcaata 58560
gctgagtcta tatcccattg atgaattcct actgcgacac gcattaacat gtgctgaggt 58620
ctttcaacga tcttgttgtt tattttcaac aagtaggatt tttccaaagt tttaaaacca 58680
aaatagttgt atgaaaagtc tcgttcgtaa ataataaccg agttgagttt atccttatat 58740
ttgttaacta tatccatggt gatacttgaa ataatcggag aatgtttccc atttttagga 58800
ttaacatagt tgaataaatc ctccatcact tcactaaata gtttttttgt ttccttgtgt 58860
agatttgata cggctattct ggcggctaga atggcataat ccggatgttg tgtagtacaa 58920
gtggctgcta tttcggctgc cagagtgtcc aattctaccg ttgttactcc attatatatt 58980
ccttgaataa ccttcatagc tattttaata ggatctatat gatccgtgtt taagccataa 59040
cataattttc taatacgaga cgtgatttta tcaaacatga cattttcctt gtatccattt 59100
cgtttaatga caaacatttt tgttggtgta ataaaaaaaa ttatttaact tttcattaat 59160
agggatttga cgtatgtagc gtacaaaatt atcgttcctg gtatatagat aaagagtcct 59220
atatatttga aaatcgttac ggctcgatta aactttaatg attgcatagt gaatatatca 59280
ttaggattta actccttgac tatcatggcg gcgccagaaa ttaccatcaa aagcattaat 59340
acagttatgc cgatcgcagt tagaacggtt atagcatcca ccatttatat ctaaaaatta 59400
gatcaaagaa tatgtgacaa agtcctagtt gtatactgag aattgacgaa acaatgtttc 59460
ttacatattt tttttttatt agtaaccgac ttaatagtag gaactggaaa actagacttg 59520
attattctat aagtatagat acccttccaa ataatattct ctttgataaa agttccagaa 59580
aatgtagaat tttttaaaaa gttatctttt gctattacca agattgtgtt tagacgctta 59640
ttattaatat gagtgatgaa atccacaccg cctctagata tcgcttttat ttccacatta 59700
gatggtaaat ccaatagtga aactatcttt ttaggaatgt atggactcgc gtttagagga 59760
gtgaacgtct taggcgtcgg aaaggggccg gccttttttt ctagacacta aataaatagt 59820
aagattaaat taattataaa attatgtata taatattaat tataaaatta tgtatatgat 59880
ttactaactt tagttagata aattaataat acataaattt tagtatatta atattataaa 59940
ttaataatac ataaatttta gtatattaat attatatttt aaatatttat ttagtgtcta 60000
gaaaaaaagg cctagcaggc c 60021
<210> 13
<211> 63035
<212> DNA
<213> 人工序列
<220>
<223> sMVA片段2
<400> 13
ggcctagcag gccttttttt ctagacacta aataaatagt aagattaaat taattataaa 60
attatgtata taatattaat tataaaatta tgtatatgat ttactaactt tagttagata 120
aattaataat acataaattt tagtatatta atattataaa ttaataatac ataaatttta 180
gtatattaat attatatttt aaatatttat ttagtgtcta gaaaaaaagg ccggccataa 240
aaatgttttt gtttaaccac tgcatgatgt acagatttcg gaatcgcaaa ccaccagtgg 300
ttttatttta tccttgtcca atgtgaattg aatgggagcg gatgcgggtt tcgtacgtag 360
atagtacatt cccgttttta gaccgagact ccatccgtaa aaatgcatac tcgttagttt 420
ggaataactc ggatctgcta tatggatatt catagattga ctttgatcga tgaaggctcc 480
cctgtctgca gccattttta tgatcgtctt ttgtggaatt tcccaaatag ttttataaac 540
tcgcttaata tcttctggaa ggtttgtatt ctgaatggat ccaccatctg ccataatcct 600
attcttgatc tcatcattcc ataattttct ctcggttaaa actctaagga gatgcggatt 660
aactacttga aattctccag acaatactct ccgagtgtaa atattactgg tatacggttc 720
caccgactca ttatttccca aaatttgagc agttgatgca gtcggcatag gtgccaccaa 780
taaactattt ctaagaccgt atgttctgat tttatctttt agaggttccc aattccaaag 840
atccgacggt acaacattcc aaagatcata ttgtagaata ccgttactgg cgtacgatcc 900
tacatatgta tcgtatggtc cttccttctc agctagttca caactcgcct ctaatgcacc 960
gtaataaatg gtttcgaaga tcttcttatt tagatcttgt gcttccaggc tatcaaatgg 1020
ataatttaag agaataaacg cgtccgctaa tccttgaaca ccaataccga taggtctatg 1080
tctcttatta gagatttcag cttctggaat aggataataa ttaatatcta taattttatt 1140
gagatttctg acaattactt tgaccacatc cttcagtttg agaaaatcaa atcgcccatc 1200
tattacaaac atgttcaagg caacagatgc cagattacaa acggctacct cattagcatc 1260
cgcatattgt attatctcag tgcaaagatt actacacttg atagttccta aattttgttg 1320
attactcttt ttgttacacg catccttata aagaatgaat ggagtaccag tttcaatctg 1380
agattctata atcgctttcc agacgactcg agcctttatt atagatttgt atctcctttc 1440
tctttcgtat agtgtataca atcgttcgaa ctcgtctccc caaacattgt ccaatccagg 1500
acattcatcc ggacacatca acgaccactc tccgtcatcc ttcactcgtt tcataaagag 1560
atcaggaatc caaagagcta taaatagatc tctggttcta tgttcctcgt ttcctgtatt 1620
ctttttaaga tcgaggaacg ccataatatc agaatgccac ggttccaagt atatggccat 1680
aactccaggc cgtttgtttc ctccctgatc tatgtatcta gcggtgttat tataaactct 1740
caacattgga ataataccgt ttgatatacc attggtaccg gagatatagc ttccactggc 1800
acgaatatta ctaattgata gacctattcc ccctgccatt ttagagatta atgcgcatcg 1860
ttttaacgtg tcatagatac cctctatgct atcatcgatc atgttaagta gaaaacagct 1920
agacatttgg tgacgactag ttcccgcatt aaataaggta ggagaagcgt gcgtaaacca 1980
tttttcagaa agtagattgt acgtctcaat agctgagtct atatcccatt gatgaattcc 2040
tactgcgaca cgcattaaca tgtgctgagg tctttcaacg atcttgttgt ttattttcaa 2100
caagtaggat ttttccaaag ttttaaaacc aaaatagttg tatgaaaagt ctcgttcgta 2160
aataataacc gagttgagtt tatccttata tttgttaact atatccatgg tgatacttga 2220
aataatcgga gaatgtttcc catttttagg attaacatag ttgaataaat cctccatcac 2280
ttcactaaat agtttttttg tttccttgtg tagatttgat acggctattc tggcggctag 2340
aatggcataa tccggatgtt gtgtagtaca agtggctgct atttcggctg ccagagtgtc 2400
caattctacc gttgttactc cattatatat tccttgaata accttcatag ctattttaat 2460
aggatctata tgatccgtgt ttaagccata acataatttt ctaatacgag acgtgatttt 2520
atcaaacatg acattttcct tgtatccatt tcgtttaatg acaaacattt ttgttggtgt 2580
aataaaaaaa attatttaac ttttcattaa tagggatttg acgtatgtag cgtacaaaat 2640
tatcgttcct ggtatataga taaagagtcc tatatatttg aaaatcgtta cggctcgatt 2700
aaactttaat gattgcatag tgaatatatc attaggattt aactccttga ctatcatggc 2760
ggcgccagaa attaccatca aaagcattaa tacagttatg ccgatcgcag ttagaacggt 2820
tatagcatcc accatttata tctaaaaatt agatcaaaga atatgtgaca aagtcctagt 2880
tgtatactga gaattgacga aacaatgttt cttacatatt ttttttttat tagtaaccga 2940
cttaatagta ggaactggaa aactagactt gattattcta taagtataga tacccttcca 3000
aataatattc tctttgataa aagttccaga aaatgtagaa ttttttaaaa agttatcttt 3060
tgctattacc aagattgtgt ttagacgctt attattaata tgagtgatga aatccacacc 3120
gcctctagat atcgctttta tttccacatt agatggtaaa tccaatagtg aaactatctt 3180
tttaggaatg tatggactcg cgtttagagg agtgaacgtc ttaggcgtcg gaaaggatga 3240
ttcatcaaac gaataaacaa tttcacaaat ggatgttaat gtattagtag gaaatttttt 3300
gacgctagtg gaattgaaga ttctaatgga tgatgttcta cctatttcat ccgataacat 3360
gttaatttcc gacaccaacg gttttaatat ttcgatgata tacggtagtc tctctttcgg 3420
acttatatag cttattccac aatacgagtc attatatact ccaaaaaaca aaataactag 3480
tataaaatct gtatcgaatg ggaaaaacga aattatcgac ataggtatag aatctggaac 3540
attgaacgta ttaatactta attctttttc tgtggtaagt accgataggt tattgacatt 3600
gtatggtttt aaatattcta taacttgaga cttgatagat attagtgatg aattgaaaat 3660
tatttttatc accacgtgtg tttcaggatc atcgtcgacg cccgtcaacc aaccgaatgg 3720
agtaaaataa atatcattaa tatatgctct agatattagt atttttatca atcctttgat 3780
tatcatcttc tcgtaggcga atgattccat gatcaagagt gatttaagaa catcctccgg 3840
agtattaatg ggcttagtaa acagtccatc gttgcaataa taaaagttat ccaagttaaa 3900
ggatattatg cattcgttta aagatatcac ctcatctgac ggagacaatt ttttggtagg 3960
ttttagagac tttgaagcta cttgtttaac aaagttattc atcgtcgttt actattctat 4020
ttaattttgt agttaattta tcacatatca cattaattga ctttttggtc catttttcca 4080
tacgtttata ttcttttaat cctgcgttat ccgtttccgt tatatccagg gatagatctt 4140
gcaagttaaa tagaatgctc ttaaataatg tcattttctt atccgctaaa aatttaaaga 4200
atgtataaac ctttttcaga gatttgaaac tcttaggtgg tgtcctagta cacaatatca 4260
taaacaaact aataaacatt ccacattcag attccaacag ctgattaact tctacattaa 4320
tacagcctat tttcgctcca aatgtacatt cgaaaaatct gaataaaaca tcgatgtcac 4380
aatttgtatt atccaataca gaatgtttgt gattcgtgtt aaaaccatcg gagaaggaat 4440
aaaaataaaa attattatag tggtggaatt cagttggaat attgcctccg gagtcataaa 4500
aggatactaa acattgtttt ttatcataaa ttacacattt ccaatgagac aaataacaaa 4560
atccaaacat tacaaatcta gaggtagaac ttttaatttt gtctttaagt atatacgata 4620
agatatgttt attcataaac gcgtcaaatt tttcatgaat cgctaaggag tttaagaatc 4680
tcatgtcaaa ttgtcctata taatccactt cggatccata agcaaactga gagactaagt 4740
tcttaatact tcgattgctc atccaggctc ctctctcagg ctctattttc atcttgacga 4800
cctttggatt ttcaccagta tgtattcctt tacgtgataa atcatcgatt ttcaaatcca 4860
tttgtgagaa gtctatcgcc ttagatactt tttcccgtag tcgaggttta aagaaatacg 4920
ctaacggtat actagtaggt aactcaaaga catcatatat agaatggtaa cgcgtcttta 4980
actcgtcggt taactctttc ttttgatcga gttcgtcgct actattgggt ctgctcaggt 5040
gccccgactc tactagttcc aacatcatac cgataggaat acaagacact ttgccggcgg 5100
ttgtagattt atcatatttc tccactacat atccgttaca atttgttaaa aatttagata 5160
catctatatt gctacataat ccagctagtg aatatatatg acataataaa ttggtaaatc 5220
ctagttctgg tattttacta attactaaat ctgtatatct ttccatttat catggaaaag 5280
aatttaccag atatcttctt ttttccaaac tgcgttaatg tattctctta caaatattca 5340
caagatgaat tcagtaatat gagtaaaacg gaacgtgata gtttctcatt ggcggtgttt 5400
ccagttataa aacatagatg gcataacgca cacgttgtaa aacataaagg aatatacaaa 5460
gttagtacag aagcacgtgg aaaaaaagta tctcctccat cactaggaaa acccgcacac 5520
ataaacctaa ccgcgaagca atatatatac agtgaacaca caataagctt tgaatgttat 5580
agttttctaa aatgtataac aaatacagaa atcaattcgt tcgatgagta tatattaaga 5640
ggactattag aagctggtaa tagtttacag atattttcca attccgtagg taaacgaaca 5700
gatactatag gtgtactagg gaataagtat ccatttagca aaattccatt ggcctcatta 5760
actcctaaag cacaacgaga gatattttca gcgtggattt ctcatagacc tgtagtttta 5820
actggaggaa ctggagtggg taagacgtca caggtaccca agttattgct ttggtttaat 5880
tatttatttg gtggattctc tactctagat aaaatcactg actttcacga aagaccagtc 5940
attctatctc ttcctaggat agctttagtt agattgcata gcaataccat tttaaaatca 6000
ttgggattta aggtactaga tggatctcct atttctttac ggtacggatc tataccggaa 6060
gaattaataa acaaacaacc aaaaaaatat ggaattgtat tttctaccca taagttatct 6120
ctaacaaaac tatttagtta tggcactctt attatagacg aagttcatga gcatgatcaa 6180
ataggagata ttattatagc agtagcgaga aagcatcata cgaaaataga ttctatgttt 6240
ttaatgactg ccacgttaga ggatgacagg gaacggctaa aagtattttt acctaatccc 6300
gcatttatac atattcctgg agatacactg tttaaaatta gcgaggtatt tattcataat 6360
aagataaatc catcttccag aatggcatac atagaagaag aaaagagaaa tttagttact 6420
gctatacaga tgtatactcc tcctgatgga tcatccggta tagtctttgt ggcatccgtt 6480
gcacagtgtc acgaatataa atcatattta gaaaaaagat taccgtatga tatgtatatt 6540
attcatggta aggtcttaga tatagacgaa atattagaaa aagtgtattc atcacctaat 6600
gtatcgataa ttatttctac tccttatttg gaatccagcg ttactatacg caatgttaca 6660
cacatttatg atatgggtag agtttttgtc cccgctcctt ttggaggatc gcaagaattt 6720
atttctaaat ctatgagaga tcaacgaaaa ggaagagtag gaagagttaa tcctgggaca 6780
tacgtatatt tctatgatct gtcttatatg aagtctatac agcgaataga ttcagaattt 6840
ctacataatt atatattgta cgctaataag tttaatctaa cactccccga agatttgttt 6900
ataatcccta caaatttgga tattctatgg cgtacaaagg aatatataga ctcgttcgat 6960
attagtacag aaacatggaa taaattatta tccaattatt atatgaagat gatagagtat 7020
gctaaacttt atgtactaag tcctattctc gctgaggagt tggataattt tgagaggacg 7080
ggagaattaa ctagtattgt acaagaagcc attttatctc taaatttacg aattaagatt 7140
ttaaatttta aacataaaga tgatgatacg tatatacact tttgtaaaat attattcggt 7200
gtctataacg gaacaaacgc tactatatat tatcatagac ctctaacggg atatatgaat 7260
atgatttcag atactatatt tgttcctgta gataataact aaaaatcaaa ctctaatgac 7320
cacatctttt tttagagatg aaaaattttc cacatctcct tttgtagaca cgactaaaca 7380
ttttgcagaa aaaagtttat tagtgtttag ataatcgtat acttcatcag tgtagatagt 7440
aaatgtgaac agataaaagg tattcttgct caatagattg gtaaattcca tagaatatat 7500
taatcctttc ttcttgagat cccacatcat ttcaaccaga gacgttttat ccaatgattt 7560
acctcgtact ataccacata caaaactaga ttttgcagtg acgtcgtatc tggtattcct 7620
accaaacaaa attttacttt tagttctttt agaaaattct aaggtagaat ctctatttgc 7680
caatatgtca tctatggaat taccactagc aaaaaatgat agaaatatat attgatacat 7740
cgcagctggt tttgatctac tatactttaa aaacgaatca gattccataa ttgcctgtat 7800
atcatcagct gaaaaactat gttttacacg tattccttcg gcatttcttt ttaatgatat 7860
atcttgttta gacaatgata aagttatcat gtccatgaga gacgcgtctc cgtatcgtat 7920
aaatatttca ttagatgtta gacgcttcat taggggtata cttctataag gtttcttaat 7980
cagtccatca ttggttgcgt caagaactac tatcggatgt tgttgggtat ctctagtgtt 8040
acacatggcc ttactaaagt ttgggtaaat aactatgata tctctattaa ttatagatgc 8100
atatatttca tttgtcaagg atattagtat cgacttgcta tcgtcattaa tacgtgtaat 8160
gtaatcatat aaatcatgcg atagccaagg aaaatttaaa tagatgttca tcatataatc 8220
gtcgctataa ttcatattaa tacgttgaca ttgactaatt tgtaatatag cctcgccacg 8280
aagaaagctc tcgtattcag tttcatcgat aaaggatacc gttaaatata actggttgcc 8340
gatagtctca tagtctatta agtggtaagt ttcgtacaaa tacagaatcc ctaaaatatt 8400
atctaatgtt ggattaatct ttaccataac tgtataaaat ggagacggag tcataactat 8460
tttaccgttt gtacttactg gaatagacga aggaataatc tccggacatg ctggtaaaga 8520
cccaaatgtc tgtttgaaga aatccaatgt tccaggtcct aatctcttaa caaaaattac 8580
gatattcgat cccgatatcc tttgcattct atttaccagc atatcacgaa ctatattaag 8640
attatctatc atgtctattc tcccaccgtt atataaatcg cctccgctaa gaaacgttag 8700
tatatccata caatggaata cttcatttct aaaatagtat tcgttttcta attctttaat 8760
gtgaaatcgt atactagaaa gggaaaaatt atctttgagt tttccgttag aaaagaacca 8820
cgaaactaat gttctgattg cgtccgattc cgttgctgaa ttaatggatt tacaccaaaa 8880
actcatataa cttctagatg tagaagcatt cgctaaaaaa ttagtagaat caaaggatat 8940
aagtagatgt tccaacaagt gagcaattcc caagatttca tctatatcat tctcgaatcc 9000
gaaattagaa attcccaagt agatatcctt tttcatccga tcgttgatga aaatacgaac 9060
tttattcggt aagacaatca tttactaagg agtaaaatag gaagtaatgt tcgtatgtcg 9120
ttatcatcgt ataaattaaa ggtgtgtttt ttaccattaa gtgacattat aattttacca 9180
atattggaat tataatatag gtgtatttgc gcactcgcga cggttgatgc atcggtaaat 9240
atagctgtat ctaatgttct agtcggtatt tcatcatttc gctgtctaat aatagcgttt 9300
tctctatctg tttccattac agctgcctga agtttattgg tcggataata tgtaaaataa 9360
taagaaatac atacgaataa caaaaataaa ataagatata ataaagatgc catttagaga 9420
tctaattttg tttaacttgt ccaaattcct acttacagaa gatgaggaat cgttggagat 9480
agtgtcttcc ttatgtagag gatttgaaat atcttatgat gacttgataa cttactttcc 9540
agataggaaa taccataaat atatttctaa agtatttgaa catgtagatt tatcggagga 9600
attaagtatg gaattccatg atacaactct gagagattta gtctatctta gattgtacaa 9660
gtattccaag tgtatacggc cgtgttataa attaggagat aatctaaaag gcatagttgt 9720
tataaaggac aggaatattt atattagaga agcaaatgat gacttgatag aatatctcct 9780
caaggaatac actcctcaga tttatacata ttctaatgag cgcgtcccca taactggttc 9840
aaaattaatt ctttgtggat tttctcaagt tacatttatg gcgtatacaa cgtcgcatat 9900
aacaacaaat aaaaaggtag atgttctcgt ttccaaaaaa tgtatagatg aactagtcga 9960
tccaataaat tatcaaatac ttcaaaattt atttgataaa ggaagcggaa caataaacaa 10020
aatactcagg aagatatttt attcggtaac cggtggccaa actccataat ttgctttttc 10080
tatttcggat tttagaattt ccaaattcac cagcgattta tcggttttgg tgaaatccaa 10140
ggatttatta atgtccacaa atgccatttg ttttgtctgt ggattgtatt tgaaaatgga 10200
aacgatgtag ttagatagat gcgctgcaaa gtttcctatt agggttccgc gctttacgtc 10260
acccagcata cttgaatcac catcctttaa aaaaaatgat aagatatcaa catggagtat 10320
atcatactcg gattttaatt cttctactgc atcactgaca ttttcacaaa tactacaata 10380
cggtttaccg aaaataatca gtacgttctt catttatggg tatcaaaaac ttaaaatcgt 10440
tactgctgga aaataaatca ctgacgatat tagatgataa tttatacaaa gtatacaatg 10500
gaatatttgt ggatacaatg agtatttata tagccgtcgc caattgtgtc agaaacttag 10560
aagagttaac tacggtattc ataaaatacg taaacggatg ggtaaaaaag ggagggcatg 10620
taaccctttt tatcgataga ggaagtataa aaattaaaca agacgttaga gacaagagac 10680
gtaaatattc taaattaacc aaggacagaa aaatgctaga attagaaaag tgtacatccg 10740
aaatacaaaa tgttaccgga tttatggaag aagaaataaa ggcagaaatg caattaaaaa 10800
tcgataaact cacatttcaa atatatttat ctgattctga taacataaaa atatcattga 10860
atgagatact aacacatttc aacaataatg agaatgttac attattttat tgtgatgaac 10920
gagacgcaga attcgttatg tgtctcgagg ctaaaacaca tttctctacc acaggagaat 10980
ggccgttgat aataagtacc gatcaggata ctatgctatt tgcatctact gataatcatc 11040
ctaagatgat aaaaaactta actcaactgt ttaaatttgt tccctcggca gaggataact 11100
atttagcaaa attaacggcg ttagtgaatg gatgtgattt ctttcctgga ctctatgggg 11160
catctataac acccaccaac ttaaacaaaa tacaattgtt tagtgatttt acaatcgata 11220
atatagtcac tagtttggca attaaaaatt attatagaaa gactaactct accgtagacg 11280
tgcgtaatat tgttacgttt ataaacgatt acgctaattt agacgatgtc tactcgtatg 11340
ttcctccttg tcaatgcact gttcaagaat ttatattttc cgcattagat gaaaaatgga 11400
acaattttaa atcatcttat ttagagaccg ttccgttacc ctgccaatta atgtatgcat 11460
tagaaccacg caaggagatt gatgtttcag aagttaaaac tttatcatct tatatagatt 11520
tcgaaaatac taaatcagat atcgatgtta taaaatctat atcttcgatc ttcggatatt 11580
ctaacgaaaa ctgtaacact atagtgttcg gcatctataa ggataattta ctactgagta 11640
taaatagttc attttacttt aacgatagtc tgttaataac caatactaaa agtgataata 11700
taataaatat aggttactag attaaaaatg gtgttccaac tcgtgtgctc tacgtgcggc 11760
aaagatattt ctcacgaacg atataaattg attatacgaa aaaaatcatt aaaggatgta 11820
ctcgtcagtg taaagaacga atgttgtagg ttaaaattat ctacacaaat agaacctcaa 11880
cgtaacttaa cagtgcaacc tctattggat ataaactaat atggatccgg ttaattttat 11940
caagacatat gcgcctagag gttctattat ttttattaat tataccatgt cattaacaag 12000
tcatttgaat ccatcgatag aaaaacatgt gggtatttat tatggtacgt tattatcgga 12060
acacttggta gttgaatcta cctatagaaa aggagttcga atagtcccat tggatagttt 12120
ttttgaagga tatcttagtg caaaagtata catgttagag aatattcaag ttatgaaaat 12180
agcagctgat acgtcattaa ctttattggg tattccgtat ggatttggtc ataatagaat 12240
gtattgtttt aaattggtag ctgaatgtta taaaaatgcc ggtattgata catcgtctaa 12300
acgaatatta ggtaaagata tttttctgag ccaaaacttc acagatgata atagatggat 12360
aaagatatat gattctaata atttaacatt ttggcaaatt gattacctta aagggtgagt 12420
taatatgcat aactactcct ccgttgtttt ttccctcgtt ctttttctta acgttgtttg 12480
ccatcactct cataatgtaa agatattcta aaatggtaaa cttttgcata tcggacgcag 12540
aaattggtat aaatgttgta attgtattat ttcccgtcaa tggactagtc acagctccat 12600
cagttttata tcctttagag tatttctcac tcgtgtctaa cattctagag cattccatga 12660
tctgtttatc gttgatattg gccggaaaga tagatttttt attttttatt atattactat 12720
tggcaattgt agatataact tctggtaaat atttttctac cttttcaatc tcttctattt 12780
tcaagccggc tatatattct gctatattgt tgctagtatc aatacctttt ctggctaaga 12840
agtcatatgt ggtattcact atatcagttt taactggtag ttccattagc ctttccactt 12900
ctgcagaata atcagaaatt ggttctttac cagaaaatcc agctactata ataggctcac 12960
cgatgatcat tggcaaaatc ctatattgta ccagattaat gagagcatat ttcatttcca 13020
ataattctgc tagttcttga gacattgatt tatttgatga atctagttgg ttctctagat 13080
actctaccat ttctgccgca tacaataact tgttagataa aatcagggtt atcaaagtgt 13140
ttagcgtggc tagaatagtg ggcttgcatg tattaaagaa tgcggtagta tgagtaaacc 13200
gttttaacga attatatagt ctccagaaat ctgtggcgtt acatacatga gccgaatgac 13260
atcgaagatt gtccaatatt tttaatagct gctctttgtc cattatttct atatttgact 13320
cgcaacaatt gtagatacca ttaatcactg attccttttt cgatgccgga caatagcaca 13380
attgtttagc tttggactct atgtattcag aattaataga tatatctctc aatacagatt 13440
gcactataca ttttgaaact atgtcaaaaa ttgtagaacg acgctgttct gcagccattt 13500
aactttaaat aatttacaaa aatttaaaat gagcatccgt ataaaaatcg ataaactgcg 13560
ccaaattgtg gcatattttt cagagttcag tgaagaagta tctataaatg tagactcgac 13620
ggatgagtta atgtatattt ttgccgcctt gggcggatct gtaaacattt gggccattat 13680
acctctcagt gcatcagtgt tctaccgcgg agccgaaaac attgtgttta atcttcctgt 13740
gtccaaggta aaatcgtgtt tgtgtagttt tcacaatgat gccatcatag atatagaacc 13800
tgatctggaa aataatctag taaaactttc tagttatcat gtagtaagtg tcgattgtaa 13860
caaggaactg atgcctatta ggacagatac tactatttgt ctaagtatag atcaaaagaa 13920
atcttacgtg tttaattttc acaagtatga agaaaaatgt tgtggtagaa ccgtcattca 13980
tttagaatgg ttgttgggct ttatcaagtg tattagtcag catcagcatt tggctattat 14040
gtttaaagat gacaatatta ttatgaagac tcctggtaat actgatgcgt tttccaggga 14100
atattctatg actgaatgtt ctcaagaact acaaaagttt tctttcaaaa tagctatctc 14160
gtctctcaac aaactacgag gattcaaaaa gagagtcaat gtttttgaaa ctagaatcgt 14220
aatggataat gacgataaca ttctaggaat gttgttttcg gatagagttc aatcctttaa 14280
gatcaacatc tttatgacgt ttttagatta atactttcaa tgagataaat atgggtggca 14340
gagtaagtgt tgagctccct aaacgggatc cgcctccggg agtacccact gatgagatgt 14400
tattaaacgt ggataaaatg catgacgtga tagctcccgc taagctttta gaatatgtgc 14460
atataggacc actagcaaaa gataaagagg ataaagtaaa gaaaagatat ccagagttta 14520
gattagtcaa cacaggaccc ggtggtcttt cggcattgtt aagacaatcg tataatggaa 14580
ccgcacccaa ttgctgtcgc acttttaatc gtactcatta ttggaaaaag gatggaaaga 14640
tatcagataa gtatgaagag ggtgcagtat tagaatcgtg ttggccagac gttcacgaca 14700
ctggaaaatg cgatgttgat ttattcgact ggtgtcaggg ggatacgttc gatagaaaca 14760
tatgccatca gtggatcggt tcagccttta ataggagtga tagaactgta gagggtcaac 14820
aatcgttaat aaatctgtat aataagatgc aaacattatg tagtaaagat gctagtgtac 14880
caatatgtga atcatttttg catcatttac gcgcacacaa tacagaagat agcaaagaga 14940
tgatcgatta tattctaaga caacagtctg cggactttaa acagaaatat atgagatgta 15000
gttatcccac tagagataag ttagaagagt cattaaaata tgcggaacct cgagaatgtt 15060
gggatccaga gtgttcgaat gccaatgtta atttcttact aacacgtaat tataataatt 15120
taggactttg caatattgta cgatgtaata ctagcgtgaa caacttacag atggataaaa 15180
cttcctcatt aagattgtca tgtggattaa gcaatagtga tagattttct actgttcccg 15240
tcaatagagc aaaagtagtt caacataata ttaaacattc gttcgaccta aaattgcatt 15300
tgatcagttt attatctctc ttggtaatat ggatactaat tgtagctatt taaatgggtg 15360
ccgcggcaag catacagacg acggtgaata cactcagcga acgtatctcg tctaaattag 15420
aacaagaagc gaacgctagt gctcaaacaa aatgtgatat agaaatcgga aatttttata 15480
tccgacaaaa ccatggatgt aacctcactg ttaaaaatat gtgctctgcg gacgcggatg 15540
ctcagttgga tgctgtgtta tcagccgcta cagaaacata tagtggatta acaccggaac 15600
aaaaagcata cgtaccagct atgtttactg ctgcgttaaa cattcagacg agtgtaaaca 15660
ctgttgttag agattttgaa aattatgtga aacagacttg taattctagc gcggtcgtcg 15720
ataacaaatt aaagatacaa aacgtaatca tagatgaatg ttacggagcc ccaggatctc 15780
caacaaattt ggaatttatt aatacaggat ctagcaaagg aaattgtgcc attaaagcgt 15840
tgatgcaatt gacgactaag gccactactc aaatagcacc tagacaagtt gctggtacag 15900
gagttcagtt ttatatgatt gttatcggtg ttataatatt ggcagcgttg tttatgtact 15960
atgccaagcg tatgttgttc acatccacca atgataaaat caaacttatt ttagccaata 16020
aggaaaacgt ccattggact acttacatgg acacattctt tagaacttct ccgatggtta 16080
ttgctaccac ggatatgcaa aactgaaaat atattgataa tattttaata gattaacatg 16140
gaagttatcg ctgatcgtct agacgatata gtgaaacaaa atatagcgga tgaaaaattt 16200
gtagattttg ttatacacgg tctagagcat caatgtcctg ctatacttcg accattaatt 16260
aggttgttta ttgatatact attatttgtt atagtaattt atatttttac ggtacgtcta 16320
gtaagtagaa attatcaaat gttgttggcg ttggtggcgc tagtcatcac attaactatt 16380
ttttattact ttatactata atagtactag actgacttct aacaaacatc tcacctgcca 16440
taaataaatg cttgatatta aagtcttcta tttctaacac tattccatct gtggaaaata 16500
atactctgac attatcgcta attgacacat cggtgagtga tatgcctata aagtaataat 16560
cttctttggg cacatatacc agtgtaccag gttctaacaa cctatttact ggtgctcctg 16620
tagcatactt tttctttacc ttgagaatat ccatcgtttg cttggtcaat agcgatatgt 16680
gattttttat caaccactca aaaaagtaat tggagtgttc atatcctcta cgggctattg 16740
tctcatggcc gtgtatgaaa tttaagtaac acgactgtgg tagatttgtt ctatagagcc 16800
ggttgccgca aatagataga actaccaata tgtctgtaca aatgttaaac attaattgat 16860
taacagaaaa aacaatgttc gttctgggaa tagaaaccag atcaaaacaa aattcgttag 16920
aatatatgcc acgtttatac atggaatata aaataactac agtttgaaaa ataacagtat 16980
catttaaaca tttaacttgc ggggttaatt tcacaacttt actgttttta aactgttcaa 17040
aatatagcat cgatccatga gaaatacgtt tagccgcctt taatagagga aatcccaccg 17100
cctttctgga tctcaccaac gacgatagtt ctgaccagca acttatttct tcatcatcca 17160
cctgttttaa catataatag gcaggagata gatatccgtc attgcaatat tccttttcgt 17220
aggcacacaa tctaatattg ataaaatctc cattctcttc tctgcattta ttatcttgtt 17280
tcggtggctg attaggctgt agtcttggtt taggctttgg tatatcgttg ttgaatctat 17340
tttggtcatt aaatctttca tttcttcctg gtatatttct atcacctcgt ttggttggat 17400
ttttgtctat attatcgttt gtaacatcgg tacgggtatt catttatcac aaaaaaaact 17460
tctctaaatg agtctactgc tagaaaacct catcgaagaa gataccatat tttttgcagg 17520
aagtatatct gagtatgatg atttacaaat ggttattgcc ggcgcaaaat ccaaatttcc 17580
aagatctatg ctttctattt ttaatatagt acctagaacg atgtcaaaat atgagttgga 17640
gttgattcat aacgagaata tcacaggggc aatgtttacc acaatgtata atataagaaa 17700
caatttgggt ctaggagatg ataaactaac tattgaagcc attgaaaact atttcttgga 17760
tcctaacaat gaggttatgc ctcttatcat taataatacg gatatgactg ccgtcattcc 17820
taaaaaaagt ggtaggagaa agaataagaa catggttatt ttccgtcaag gatcatcacc 17880
tatcttgtgt attttcgaaa ctcgtaaaaa gattaatatt tataaagaaa atatggaatc 17940
cgcgtcgact gagtatacac ctatcggaga caacaaggct ttgatatcta aatatgcggg 18000
aattaatgtc ctgaatgtgt attctccttc cacatccatg agattgaatg ccatttacgg 18060
attcaccaat aaaaataaac tagagaaact tagtactaat aaggaactag aatcgtatag 18120
ttctagccct cttcaagaac ccattaggtt aaatgatttt ctgggactat tggaatgtgt 18180
taaaaagaat attcctctaa cagatattcc gacaaaggat tgattactat aaatggagaa 18240
tgttcctaat gtatacttta atcctgtgtt tatagagccc acgtttaaac attctttatt 18300
aagtgtttat aaacacagat taatagtttt atttgaagta ttcattgtat tcattctaat 18360
atatgtattt tttagatctg aattaaatat gttcttcatg cctaaacgaa aaatacccga 18420
tcctattgat agattacgac gtgctaatct agcgtgtgaa gacgataaat taatgatcta 18480
tggattacca tggatgacaa ctcaaacatc tgcgttatca ataaatagta aaccgatagt 18540
gtataaagat tgtgcaaagc ttttgcgatc aataaatgga tcacaaccag tatctcttaa 18600
cgatgttctt cgcagatgat gattcatttt ttaagtattt ggctagtcaa gatgatgaat 18660
cttcattatc tgatatattg caaatcactc aatatctaga ctttctgtta ttattattga 18720
tccaatcaaa aaataaatta gaagccgtgg gtcattgtta tgaatctctt tcagaggaat 18780
acagacaatt gacaaaattc acagactttc aagattttaa aaaactgttt aacaaggtcc 18840
ctattgttac agatggaagg gtcaaactta ataaaggata tttgttcgac tttgtgatta 18900
gtttgatgcg attcaaaaaa gaatcctctc tagctaccac cgcaatagat cctattagat 18960
acatagatcc tcgtcgcgat atcgcatttt ctaacgtgat ggatatatta aagtcgaata 19020
aagtgaacaa taattaattc tttattgtca tcatgaacgg cggacatatt cagttgataa 19080
tcggccccat gttttcaggt aaaagtacag aattaattag acgagttaga cgttatcaaa 19140
tagctcaata taaatgcgtg actataaaat attctaacga taatagatac ggaacgggac 19200
tatggacgca tgataagaat aattttgaag cattggaagc aactaaacta tgtgatgtct 19260
tggaatcaat tacagatttc tccgtgatag gtatcgatga aggacagttc tttccagaca 19320
ttgttgaatt ctgtgagcgt atggcaaacg aaggaaaaat agttatagta gccgcactcg 19380
atgggacatt tcaacgtaaa ccgtttaata atattttgaa tcttattcca ttatctgaaa 19440
tggtggtaaa actaactgct gtgtgtatga aatgctttaa ggaggcttcc ttttctaaac 19500
gattgggtga ggaaaccgag atagagataa taggaggtaa tgatatgtat caatcggtgt 19560
gtagaaagtg ttacgtcggc tcataatatt atatttttta tctaaaaaac taaaaataaa 19620
cattgattaa attttaatat aatacttaaa aatggatgtt gtgtcgttag ataaaccgtt 19680
tatgtatttt gaggaaattg ataatgagtt agattacgaa ccagaaagtg caaatgaggt 19740
cgcaaaaaaa ctgccgtatc aaggacagtt aaaactatta ctaggagaat tattttttct 19800
tagtaagtta cagcgacacg gtatattaga tggtgccacc gtagtgtata taggatctgc 19860
tcccggtaca catatacgtt atttgagaga tcatttctat aatttaggag tgatcatcaa 19920
atggatgcta attgacggcc gccatcatga tcctatttta aatggattgc gtgatgtgac 19980
tctagtgact cggttcgttg atgaggaata tctacgatcc atcaaaaaac aactgcatcc 20040
ttctaagatt attttaattt ctgatgtgag atccaaacga ggaggaaatg aacctagtac 20100
ggcggattta ctaagtaatt acgctctaca aaatgtcatg attagtattt taaaccccgt 20160
ggcgtctagt cttaaatgga gatgcccgtt tccagatcaa tggatcaagg acttttatat 20220
cccacacggt aataaaatgt tacaaccttt tgctccttca tattcagctg aaatgagatt 20280
attaagtatt tataccggtg agaacatgag actgactcga gttaccaaat cagacgctgt 20340
aaattatgaa aaaaagatgt actaccttaa taagatcgtc cgtaacaaag tagttgttaa 20400
ctttgattat cctaatcagg aatatgacta ttttcacatg tactttatgc tgaggaccgt 20460
gtactgcaat aaaacatttc ctactactaa agcaaaggta ctatttctac aacaatctat 20520
atttcgtttc ttaaatattc caacaacatc aactgaaaaa gttagtcatg aaccaataca 20580
acgtaaaata tctagcaaaa attctatgtc taaaaacaga aatagcaaga gatccgtacg 20640
cagtaataaa tagaaacgta ctactgagat atactaccga tatagagtat aatgatttag 20700
ttactttaat aaccgttaga cataaaattg attctatgaa aactgtgttt caggtattta 20760
acgaatcatc cataaattat actccggttg atgatgatta tggagaacca atcattataa 20820
catcgtatct tcaaaaaggt cataacaagt ttcctgtaaa ttttctatac atagatgtgg 20880
taatatctga cttatttcct agctttgtta gactagatac tacagaaact aatatagtta 20940
atagtgtact acaaacaggc gatggtaaaa agactcttcg tcttcccaaa atgttagaga 21000
cggaaatagt tgtcaagatt ctctaccgtc ctaatatacc attaaaaatt gttagatttt 21060
tccgcaataa catggtaact ggagtagaga tagccgatag atctgttatt tcagtcgctg 21120
attaatcaat tagtagagat gagataagaa cattataata atcaataata tattttatat 21180
cttatatctt gtttagaaaa atgctaatat taaaatagct aacgctagta atccaatcgg 21240
aagccatttg atatctataa tagggtatct aatttcctga ttcagatagc ggacagctat 21300
attctcggta gctactcgtt tggaatcaca aacattattt acatctaatt tactatctgt 21360
aatggaaacg tttcccaatg aaatggtaca atccgataca ttgcattttg ttatattttt 21420
ttttaaagag gctggtaaca acgcatcgct tcgtttacat ggctcgtacc aacaataata 21480
gggtaatctt gtatctattc ctatccgtac tatgctttta tcaggataaa tacatttaca 21540
tcgtatatcg tctttgttag catcacagaa tgcataaatt tgttcgtccg tcatgataaa 21600
aatttaaagt gtaaatataa ctattatttt atagttgtaa taaaaaggga aatttgattg 21660
tatactttcg gttctttaaa agaaactgac ttgataaaaa tggctgtaat ctctaaggtt 21720
acgtatagtc tatatgatca aaaagagatt aatgctacag atattatcat tagtcatgtt 21780
aaaaatgacg acgatatcgg taccgttaaa gatggtagac taggtgctat ggatggggca 21840
ttatgtaaaa cttgtgggaa aacggaattg gaatgtttcg gtcactgggg taaagtaagt 21900
atttataaaa ctcatatagt taagcctgaa tttatttcag aaattattcg tttactgaat 21960
tatatatgta ttcactgcgg attattgcgt tcacgagaac cgtattccga cgatattaac 22020
ctaaaagagt tatcgggaca cgctcttagg agattaaagg ataaaatatt atccaagaaa 22080
aagtcatgtt ggaacagtga atgtatgcaa ccgtatcaaa aaattacttt ttcaaagaaa 22140
aaggtttgtt tcgtcaacaa gttggatgat attaacgttc ctaattctct catctatcaa 22200
aagttaattt ctattcatga aaagttttgg ccattattag aaattcatca atatccagct 22260
aacttatttt atacagacta ctttcccatc cctccgttga ttattagacc ggctattagt 22320
ttttggatag atagtatacc caaagaaacc aatgaattaa cttacttatt aggtatgatc 22380
gttaagaatt gtaacttgaa tgctgatgaa caggttatcc agaaggcggt aatagaatac 22440
gatgatatta aaattatttc taataacact tccagtatca atttatcata tatcacatcc 22500
ggcaaaaata atatgattag aagttatatc gtcgcccggc gaaaagatca gaccgctaga 22560
tctgtaattg gtcccagtac atctatcacc gttaatgagg taggaatgcc cgcatatatt 22620
agaaatacac ttacagaaaa gatatttgtt aatgccttta cagtggataa agttaaacaa 22680
ctattagcgt caaaccaagt taaattttac tttaataaac gattaaacca attaacaaga 22740
atacgccaag gaaagtttat caaaaataaa atacatttat tgcctggtga ttgggtagaa 22800
gtagctgttc aagaatatac aagtattatt tttggaagac agccgtctct acatagatac 22860
aacgtcatcg cttcatctat cagagctacc gaaggagata ctatcaaaat atctcccgga 22920
attgtcaact ctcaaaatgc tgatttcgac ggagatgaag aatggatgat attggagcaa 22980
aatcctaaag ccgtaattga acaaagtatt cttatgtatc cgacgacgtt actcaaacac 23040
gatattcatg gagcccccgt ttatggatct attcaagatg aaatcgtagc agcgtattca 23100
ttgtttagga tacaagatct ttgtttagat gaagtattga acatcttggg gaaatatgga 23160
agagagttcg atcctaaagg taaatgtaaa ttcagcggta aagatatcta tacttacttg 23220
ataggtgaaa agattaatta tccgggtctc ttaaaggatg gtgaaattat tgcaaacgac 23280
gtagatagta attttgttgt ggctatgagg catctgtcat tggctggact cttatccgat 23340
cataagtcga acgtggaagg tatcaacttt attatcaagt catcttatgt ttttaagaga 23400
tatctatcta tttacggttt tggggtgaca ttcaaagatc tgagaccaaa ttcgacgttc 23460
actaataaat tggaggccat caacgtagaa aaaatagaac ttatcaaaga agcatacgcc 23520
aaatatctca acgatgtaag agacgggaaa atagttccat tatctaaagc tttagaggcg 23580
gactatgtgg aatccatgtt atccaacttg acaaatctta atatccgaga gatagaagaa 23640
catatgagac aaacgctgat agatgatcca gataataacc tcctgaaaat ggccaaagcg 23700
ggttataaag taaatcccac agaactaatg tatattctag gtacttatgg acaacagagg 23760
attgatggtg aaccagcaga gactcgagta ttgggtagag tcttacctta ctatcttcca 23820
gactctaagg atccagaagg aagaggttac attcttaatt ctttaacaaa aggattaacg 23880
ggttctcaat attacttttc gatgctggtt gcaagatctc aatctactga tatcgtctgt 23940
gaaacatcac gtaccggaac actggctaga aaaatcatta aaaagatgga ggatatggtg 24000
gtcgacggat acggacaagt agttataggt aatacgctca tcaagtacgc cgccaattat 24060
accaaaattc taggctcagt atgtaaacct gtagatctta tctatccaga tgagtccatg 24120
acttggtatt tggaaattag tgctctgtgg aataaaataa aacagggatt cgtttactct 24180
cagaaacaga aacttgcaaa aaagacattg gcgccgttta atttcctagt attcgtcaaa 24240
cccaccactg aggataatgc tattaaggtt aaggatctgt acgatatgat tcataacgtc 24300
attgatgatg tgagagagaa atacttcttt acggtatcta atatagattt tatggagtat 24360
atattcttga cgcatcttaa tccttctaga attagaatta caaaagaaac ggctatcact 24420
atctttgaaa agttctatga aaaactcaat tatactctag gtggtggaac tcctattgga 24480
attatttctg cacaggtatt gtctgagaag tttacacaac aagccctgtc cagttttcac 24540
actactgaaa aaagtggtgc cgtcaaacaa aaacttggtt tcaacgagtt taataacttg 24600
actaatttga gtaagaataa gaccgaaatt atcactctgg tatccgatga tatctctaaa 24660
cttcaatctg ttaagattaa tttcgaattt gtatgtttgg gagaattaaa tccaaacatc 24720
actcttcgaa aagaaacaga taggtatgta gtagatataa tagtcaatag attatacatc 24780
aagagagcag aaattaccga attagtcgtc gaatatatga ttgaacgatt catctccttt 24840
agcgtcattg taaaggaatg gggtatggaa acattcattg aggatgagga taatattaga 24900
tttactgtct acctaaattt cgttgaaccg gaagaattga atcttagtaa gtttatgatg 24960
gttcttccgg gtgccgccaa caagggcaag attagtaaat tcaagattcc tatctctgat 25020
tatacgggat atgacgactt caatcaaaca aaaaagctca ataagatgac tgtagaactc 25080
atgaatctaa aagaattggg ttctttcgat ttggaaaacg tcaacgtgta tcctggagta 25140
tggaatacat acgatatctt cggtatcgag gccgctcgtg aatacttgtg cgaagccatg 25200
ttaaacacct atggagaagg gttcgattat ctgtatcagc cttgtgatct tctcgctagt 25260
ttactatgtg ctagttacga accagaatca gtgaataaat tcaagttcgg cgcagctagt 25320
actcttaaga gagctacgtt cggagacaat aaagcattgt taaacgcggc tcttcataaa 25380
aagtcagaac ctattaacga taatagtagc tgccactttt ttagcaaggt ccctaatata 25440
ggaactggat attacaaata ctttatcgac ttgggtcttc tcatgagaat ggaaaggaaa 25500
ctatctgata agatatcttc tcaaaagatc aaggaaatgg aagaaacaga agacttttaa 25560
ttcttatcaa taacatattt ttctatgatc tgtcttttaa acgatggatt ttccacaaat 25620
gcgcctctca agtccctcat agaatgatac acgtataaaa aatatagcat aggcaatgac 25680
tccttatttt tagacattag atatgccaaa atcatagccc cgcttctatt tactcccgca 25740
gcacaatgaa ccaacacggg ctcgtttcgt tgatcacatt tagataaaaa ggcggttacg 25800
tcgtcaaaat atttactaat atcggtagtt gtatcatcta ccaacggtat atgaataata 25860
ttaatattag agttaggtaa tgtatattta tccatcgtca aatttaaaac atatttgaac 25920
ttaacttcag atgatggtgc atccatagca tttttataat ttcccaaata cacattattg 25980
gttactcttg tcattatagt gggagatttg gctttgtgca tatctccagt tgaacgtagt 26040
agtaagtatt tatacaaact tttcttatcc atttataacg tacaaatgga taaaactact 26100
ttatcggtaa acgcgtgtaa tttagaatac gttagagaaa aggctatagt aggcgtacaa 26160
gcagccaaaa catcaacact tatattcttt gttattatat tggcaattag tgcgctatta 26220
ctctggtttc agacgtctga taatccagtc tttaatgaat taacgagata tatgcgaatt 26280
aaaaatacgg ttaacgattg gaaatcatta acggatagca aaacaaaatt agaaagtgat 26340
agaggtagac ttctagccgc tggtaaggat gatatattcg aattcaaatg tgtggatttc 26400
ggcgcctatt ttatagctat gcgattggat aagaaaacat atctgccgca agctattagg 26460
cgaggtactg gagacgcgtg gatggttaaa aaggcggcaa aggtcgatcc atctgctcaa 26520
caattttgtc agtatttgat aaaacacaag tctaataatg ttattacttg tggtaatgag 26580
atgttaaatg aattaggtta tagcggttat tttatgtcac cgcattggtg ttccgatttt 26640
agtaatatgg aatagtgtta gataaatgcg gtaacgaatg ttcctgtaag gaaccataac 26700
agcttagatt taacgttaaa gatgagcata aacataataa acaaaattac aatcaaacct 26760
ataacattaa tatcaaacaa tccaaaaaat gaaatcagtg gagtagtaaa cgcgtacata 26820
actcctggat aacgtttagc agctgccgtt cctattctag accaaaaatt cggtttcatg 26880
ttttcgaaac ggtattctgc aacaagtcga ggatcgtgtt ctacatattt ggcggcgtta 26940
tccagtatct gcctattgat cttcatttcg ttttcgattc tggctatttc aaaataaaat 27000
cccgatgata gacctccaga ctttataatt tcatctacga tgttcagcgc cgtagtaact 27060
ctaataatat aggctgataa gctaacatca taccctcctg tatatgtgaa tatggcatga 27120
tttttgtcca ttacaagctc ggttttaact ttattgcctg taataatttc tctcatctgt 27180
aggatatcta tttttttgtc atgcattgcc ttcaagacgg gacgaagaaa cgtaatatcc 27240
tcaataacgt tatcgttttc tacaataact acatattcta cctttttatt ttctaactcg 27300
gtaaaaaaat tagaatccca tagggctaaa tgtctagcga tatttctttt cgtttcctct 27360
gtacacatag tgttacaaaa ccctgaaaag aagtgagtat acttgtcatc atttctaatg 27420
tttcctccag tccactgtat aaacgcataa tccttgtaat gatctggatc atccttgact 27480
accacaacat ttcttttttc tggcataact tcattgtcct ttacatcatc gaacttctga 27540
tcattaatat gctcatgaac attaggaaat gtttctgatg gaggtctatc aataactggc 27600
acaacaataa caggagtttt caccgccgcc atttagttat tgaaattaat catatacaac 27660
tctttaatac gagttatatt ttcgtctatc cattgtttca catttacata tttcgacaaa 27720
aagatataaa atgcgtattc caatgcttct ctgtttaatg aattactaaa atatacaaac 27780
acgtcactgt ctggcaataa atgatatctt agaatattgt aacaatttat tttgtattgc 27840
acatgttcgt gatctatgag ttcttcttcg aatggcatag gatctccgaa tctgaaaacg 27900
tataaatagg agttagaata ataatatttg agagtattgg taatatataa actctttagc 27960
ggtataatta gtttttttct ctcgatttct atttttagat gtgatggaaa aatgactaat 28020
tttgtagcat tagtatcatg aactctaatc gagatcttaa tatcttcgtc acacgttagt 28080
tctttgaagt ttttaagaga tgcatcagtt ggttcgaccg atggagtagg tgcaacaatt 28140
ttttgttcga tgtatgtatg tactggagcc attgtcttaa ctataatggt gcttgtatcg 28200
aaaaacttta atgcagataa tggaagctct tcgccgcgac tttctacatc gtaattgggt 28260
tctaacgccg atctctgaat ggatactagt tttctaagtt ctaatgtgat tctctgaaaa 28320
tgtaaatcca attcctccgg cattatagat gtgtatacat cggtaaataa aactatagta 28380
tccaacgatc ccttctcgca aattctagtc ttaaccaaaa aatcgtatat aaccacggag 28440
atggcgtatt taagagtgga ttcttctacc gttttgttct tggatttcat ataagaaact 28500
ataaagtccg cactactgtt aagaatgatt actaacgcaa ctatatagtt taaattaagc 28560
atcttggaaa cataaaataa ctctgtagac gatacttgac tttcgaataa gtttgcagac 28620
aaacgaagaa agaacagacc tctcttaatt tcagaagaaa actttttttc gtattcctga 28680
cgtctagagt ttatatcaat aagaaagtta agaattagtc ggttaatgtt gtatttcatt 28740
acccaagttt gagatttcat aatattatca aaagacatga taatattaaa gataaagcgc 28800
tgactatgaa cgaaatagct atatggttcg ctcaagaata tagtcttgtt aaacgtggaa 28860
acgataactg tatttttaat cacgtcagcg gcatctaaat taaatatagg tatatttatt 28920
ccacacactc tacaatatgc cacaccatct tcataataaa taaattcgtt agcaaaatta 28980
ttaattttag tgaaatagtt agcgtcaact ttcatagctt ccttcaatct aatttgatgc 29040
tcacacggtg cgaattccac tctaacatcc cttttccatg cctcaggttc atcgatctct 29100
ataatatcta gttttttgcg tttcacaaac acaggctcgt ctctcgcgat gagatctgta 29160
tagtaactat gtaaatgata actagataga aagatgtagc tatatagatg acgatccttt 29220
aagagaggta tgatgacttt accccaatca gatagactgt tgttatggtc ttcggaaaaa 29280
gaatttttat aaatttttcc agtattttcc aaatatacgt acttaacatc taaaaaatcc 29340
ttaatgataa taggaatgga taatccgtct attttataaa gaaatacata tcgcacatta 29400
tacttttttt tggaaatggg aataccgatg tgtctacata aatatgcaaa gtctaaatat 29460
tttttagaga atcttagttg gtccaaattc ttttccaagt acggtaatag atttttcata 29520
ttgaacggta tcttcttaat ctctggttct agttccgcat taaatgatga aactaagtca 29580
ctatttttat aactaacgat tacatcacct ctaacatcat catttaccag aatactgatc 29640
ttcttttgtc gtaaatacat gtctaatgtg ttaaaaaaaa gatcatacaa gttatacgtc 29700
atttcatctg tggtattctt gtcattgaag gataaactcg tactaatctc ttctttaaca 29760
gcctgttcaa atttatatcc tatatacgaa aaaatagcaa ccagtgtttg atcatccgcg 29820
tcaatattct gttctatcgt agtgtataac aatcgtatat cttcttctgt gatagtcgat 29880
acgttataaa ggttgataac gaaaatattt ttatttcgtg agataaagtc atcgtaggat 29940
tttggactta tattcgcgtc tagtagatat gcttttattt ttggaatgat ctcaattaga 30000
atagtctctt tagagtccat ttaaagttac aaacaactag gaaattggtt tatgatgtat 30060
aattttttta gtttttatag attctttatt ctatacttaa aaaatgaaaa taaatacaaa 30120
ggttcttgag ggttgtgtta aattgaaagc gagaaataat cataaattat ttcattatcg 30180
cgatatccgt taagtttgta tcgtaatggc gtggtcaatt acaaataaag cggatactag 30240
tagcttcaca aagatggctg aaatcagagc tcatctaaaa aatagcgctg aaaataaaga 30300
taaaaacgag gatattttcc cggaagatgt aataattcca tctactaagc ccaaaaccaa 30360
acgagccact actcctcgta aaccagcggc tactaaaaga tcaaccaaaa aggaggaagt 30420
ggaagaagaa gtagttatag aggaatatca tcaaacaact gaaaaaaatt ctccatctcc 30480
tggagtcagc gacattgtag aaagcgtggc tgctgtagag ctcgatgata gcgacgggga 30540
tgatgaacct atggtacaag ttgaagctgg taaagtaaat catagtgcta gaagcgatct 30600
ttctgaccta aaggtggcta ccgacaatat cgttaaagat cttaagaaaa ttattactag 30660
aatctctgca gtatcgacgg ttctagagga tgttcaagca gctggtatct ctagacaatt 30720
tacttctatg actaaagcta ttacaacact atctgatcta gtcaccgagg gaaaatctaa 30780
agttgttcgt aaaaaagtta aaacttgtaa gaagtaaatg cgtgcacttt tttataaaga 30840
tggtaaactc tttaccgata ataatttttt aaatcctgta tcagacgata atccagcgta 30900
tgaggttttg caacatgtta aaattcctac tcatttaaca gatgtagtag tatatgaaca 30960
aacgtgggag gaggcgttaa ctagattaat ttttgtggga agtgattcaa aaggacgtag 31020
acaatacttt tacggaaaaa tgcatgtaca gaatcgcaac gctaaaagag atcgtatttt 31080
tgttagagta tataacgtta tgaaacgaat taattgtttt ataaacaaaa atataaagaa 31140
atcgtccaca gattccaatt atcagttggc ggtttttatg ttaatggaaa ctatgttttt 31200
tattagattt ggtaaaatga aatatcttaa ggagaatgaa acagtagggt tattaacact 31260
aaaaaataaa cacatagaaa taagtcccga tgaaatagtt atcaagtttg taggaaagga 31320
caaagtttca catgaatttg ttgttcataa gtctaataga ctatataaac cgctattgaa 31380
actgacggat gattctagtc ccgaagaatt tctgttcaac aaactaagtg aacgaaaggt 31440
atacgaatgt atcaaacagt ttggtattag aatcaaggat ctccgaacgt atggagtcaa 31500
ttatacgttt ttatataatt tttggacaaa tgtaaagtcc atatctcctc ttccgtcacc 31560
aaaaaagtta atagcgttaa ctatcaaaca aactgctgaa gtggtaggtc atactccatc 31620
aatttcaaaa agagcttata tggcaacgac tattttagaa atggtaaagg ataaaaattt 31680
tttagatgta gtatctaaaa ctacgttcga tgaattccta tctatagtcg tagatcacgt 31740
taaatcatct acggatggat gatatagatc tttacacaaa taattacaag accgataaat 31800
ggaaatggat aagcgtatga aatctctcgc aatgacagct ttcttcggag agctaaacac 31860
attagatatt atggcattga taatgtctat atttaaacgc catccaaaca ataccatttt 31920
ttcagtggat aaggatggtc agtttatgat tgatttcgaa tacgataatt ataaggcttc 31980
tcaatatttg gatctgaccc tcactccgat atctggagat gaatgcaaga ctcacgcatc 32040
gagtatagcc gaacaattgg cgtgtgtgga tattattaaa gaggatatta gcgaatatat 32100
caaaactact ccccgtctta aacgatttat aaaaaaatac cgcaatagat cagatactcg 32160
tatcagtcga gatacagaaa agcttaaaat agctctagct aaaggcatag attacgaata 32220
tataaaagac gcttgttaat aagtaaatga aaaaaaacta gtcgtttata ataaaacaca 32280
atatggatgc caacatagta tcatcttcta ctattgcaac gtatatagac gctttagcga 32340
agaatgcttc agaattagaa cagaggtcta ccgcatacga aataaataat gaattggaac 32400
tagtatttat taagccgcca ttaattactt tgacaaatgt agtgaatatc tctacgattc 32460
aggaatcgtt tattcgattt accgttacta ataaggaagg tgttaaaatt agaactaaga 32520
ttccattatc taaggtacat ggtctagatg taaaaaatgt acagttagta gatgctatag 32580
ataacatagt ttgggaaaag aaatcattag tgacggaaaa tcgtcttcac aaagaatgct 32640
tgttgagact atcgacagag gaacgtcata tatttttgga ttacaagaaa tatggatcct 32700
ctatccgact agaattagtc aatcttattc aagcaaaaac aaaaaacttt acgatagact 32760
ttaagctaaa atattttcta ggatccggtg cccagtctaa aagttcttta ttacacgcta 32820
ttaatcatcc aaagtcaagg cctaatacat ctctggaaat agaattcaca cctagagaca 32880
atgaaaaagt tccatatgat gaactaataa aggaattgac gactctatca cgtcatatat 32940
ttatggcttc tccagagaat gtaattcttt ctccgcctat taacgcgcct ataaaaacct 33000
ttatgttgcc taaacaagat atagtaggtt tggatctgga aaatctatat gccgtaacta 33060
agactgacgg aattcctata actatcagag ttacatcaaa agggttgtat tgttatttta 33120
cacatcttgg ttatattatt agatatcctg ttaagagaat aatagattcc gaagtagtag 33180
tctttggtga ggcagttaag gataagaact ggaccgtata tctcattaag ctaatagagc 33240
ctgtgaatgc aatcaatgat agactagaag aaagtaagta tgttgaatct aaactagtgg 33300
atatttgtga tcggatagta ttcaagtcaa agaaatacga aggtccgttt actacaacta 33360
gtgaagtcgt cgatatgtta tctacatatt taccaaagca accagaaggt gttattctgt 33420
tctattcaaa gggacctaaa tctaacattg attttaaaat taaaaaggaa aatactatag 33480
accaaactgc aaatgtagta tttaggtaca tgtccagtga accaattatc tttggagaat 33540
cgtctatctt tgtagagtat aagaaattta gcaacgataa aggctttcct aaagaatatg 33600
gttctggtaa gattgtgtta tataacggcg ttaattatct aaataatatc tattgtttgg 33660
aatatattaa tacacataat gaagtgggta ttaagtccgt ggttgtacct attaagttta 33720
tagcagaatt cttagttaat ggagaaatac ttaaacctag aattgataaa accatgaaat 33780
atattaactc agaagattat tatggaaatc aacataatat catagtcgaa catttaagag 33840
atcaaagcat caaaatagga gatatcttta acgaggataa actatcggat gtgggacatc 33900
aatacgccaa taatgataaa tttagattaa atccagaagt tagttatttt acgaataaac 33960
gaactagagg accgttggga attttatcaa actacgtcaa gactcttctt atttctatgt 34020
attgttccaa aacattttta gacgattcca acaaacgaaa ggtattggcg attgattttg 34080
gaaacggtgc ggacctggaa aaatactttt atggagagat tgcgttattg gtagcgacgg 34140
atccggatgc tgatgctata gctagaggaa atgaaagata caacaaatta aactctggaa 34200
ttaaaaccaa gtactacaaa tttgactaca ttcaggaaac tattcgatcc gatacatttg 34260
tctctagtgt cagagaagta ttctattttg gaaagtttaa tatcatcgac tggcagtttg 34320
ctatccatta ttcttttcat ccgagacatt atgctaccgt catgaataac ttatccgaac 34380
taactgcttc tggaggcaag gtattaatca ctaccatgga cggagacaaa ttatcaaaat 34440
taacagataa aaagactttt ataattcata agaatttacc tagtagcgaa aactatatgt 34500
ctgtagaaaa aatagctgat gatagaatag tggtatataa tccatcaaca atgtctactc 34560
caatgactga atacattatc aaaaagaacg atatagtcag agtgtttaac gaatacggat 34620
ttgttcttgt agataacgtt gatttcgcta caattataga acgaagtaaa aagtttatta 34680
atggcgcatc tacaatggaa gatagaccgt ctacaaaaaa ctttttcgaa ctaaatagag 34740
gagccattaa atgtgaaggt ttagatgtcg aagacttact tagttactat gttgtttatg 34800
tcttttctaa gcggtaaata ataatatggt atgggttctg atatccccgt tctaaatgca 34860
ttaaataatt ccaatagagc gatttttgtt cctataggac cttccaactg tggatactct 34920
gtattgttaa tagatatatt aatacttttg tcgggtaaca gaggttctac gtcttctaaa 34980
aataaaagtt tgataacatc tggcctgttc ataaataaaa acttggcgat tctatatata 35040
ctcttattat caaatctagc cattgtctta tagatgtgag ctactgtagg tgtaccattt 35100
gattttcttt ctaatactat atatttctct cgaagaagtt cttgcacatc atctgggaat 35160
aaaatactac tgttgagtaa atcagttatt ttttttatat cgatattgat ggacattttt 35220
atagttaagg ataataagta tcccaaagtc gataacgacg ataacgaagt atttatactt 35280
ttaggaaatc acaatgactt tatcagatca aaattaacaa aattaaagga gcatgtattt 35340
ttttctgaat atattgtgac tccagataca tatggatctt tatgcgtcga attaaatggg 35400
tctagttttc agcacggtgg tagatatata gaggtggagg aatttataga tgctggaaga 35460
caagttagat ggtgttctac atccaatcat atatctgaag atatgcacac tgataaattt 35520
gtcatttatg atatttatac gtttgattcg ttcaagaata aacgattggt atttgtacag 35580
gtgcctccat cattaggaga tgatagctat ttgactaatc cgttattgtc tccgtattat 35640
cgtaattcag tagccagaca aatggtcaat gatatgattt ttaatcaaga ttcattttta 35700
aaatatttat tagaacatct gattagaagc cactatagag tttctaaaca tataacaata 35760
gttagataca aggataccga agaattaaat ctaacgagaa tatgttataa tagagataag 35820
tttaaggcgt ttgtattcgc ttggtttaac ggcgtttcgg aaaatgaaaa ggtactagat 35880
acgtataaaa aggtatctaa tttgatataa tgaattcagt gactgtatca cacgcgccat 35940
atactattac ttatcacgat gattgggaac cagtaatgag tcaattggta gagttttata 36000
acgaagtagc cagttggctg ctacgagacg agacgtcgcc tattcctgat aagttcttta 36060
tacagttgaa acaaccgctt agaaataaac gagtatgtgt gtgtggtata gatccgtatc 36120
cgaaagatgg aactggtgta ccgttcgaat caccaaattt tacaaaaaaa tcaattaagg 36180
agatagcttc atctatatct agattaaccg gagtaattga ttataaaggt tataacctta 36240
atataataga cggggttata ccctggaatt attacttaag ttgtaaatta ggagaaacaa 36300
aaagtcacgc gatctactgg gataagattt ccaagttact gctgcagcat ataactaaac 36360
acgttagtgt tctttattgt ttgggtaaaa cagatttctc gaatatacgg gcaaagttag 36420
aatccccggt aactaccata gtcggatatc atccagcggc tagagaccgc caattcgaga 36480
aagatagatc atttgaaatt atcaacgttt tactggaatt agacaacaag gcacctataa 36540
attgggctca agggtttatt tattaatgct ttagtgaaat tttaacttgt gttctaaatg 36600
gatgcaacta ttagaggtaa tgatgttatc tttgttctta agactatagg tgtcccgtca 36660
gcgtgcagac aaaatgaaga tccaagattt gtagaagcat ttaaatgcga cgagttagaa 36720
agatatattg agaataatcc agaatgtaca ctattcgaaa gtcttaggga tgaggaagca 36780
tactctatag tcagaatttt catggatgta gatttagacg cgtgtctaga cgaaatagat 36840
tatttaacgg ctattcaaga ttttattatc gaggtgtcaa actgtgtagc tagattcgcg 36900
tttacagaat gcggtgccat tcatgaaaat gtaataaaat ccatgagatc taatttttca 36960
ttgactaagt ctacaaatag agataaaaca agttttcata ttatcttttt agacacgtat 37020
accactatgg atacattgat agctatgaaa cgaacactat tagaattaag tagatcatct 37080
gaaaatccac taaccagatc gatagacact gccgtatata ggagaaaaac aactcttcgg 37140
gttgtaggta ctaggaaaaa tccaaattgc gacactattc atgtaatgca accaccgcat 37200
gataatatag aagattacct attcacttac gtggatatga acaacaatag ttattacttt 37260
tctctacaac gacgattgga ggatttagtt cctgataagt tatgggaacc agggtttatt 37320
tcattcgaag acgctataaa aagagtttca aaaatattca ttaattctat aataaacttt 37380
aatgatctcg atgaaaataa ttttacaacg gtaccactgg tcatagatta cgtaacacct 37440
tgtgcattat gtaaaaaacg atcgcataaa catccgcatc aactatcgtt ggaaaatggt 37500
gctattagaa tttacaaaac tggtaatcca catagttgta aagttaaaat tgttccgttg 37560
gatggtaata aactgtttaa tattgcacaa agaattttag acactaactc tgttttatta 37620
accgaacgag gagaccatat agtttggatt aataattcat ggaaatttaa cagcgaagaa 37680
cccttgataa caaaactaat tctgtcaata agacatcaac tacctaagga atattcaagc 37740
gaattactct gtccgaggaa acgaaagact gtagaagcta acatacgaga catgttaata 37800
gattcagtgg agaccgatac ctatccggat aaacttccgt ttaaaaatgg tgtattggac 37860
ctggtagacg gaatgtttta ctctggagat gatgctaaaa aatatacgtg tactgtatca 37920
accggattta aatttgacga tacaaagttc gtcgaagaca gtccagaaat ggaagagtta 37980
atgaatatca ttaacgatat ccaaccatta acggatgaaa ataagaaaaa tagagagttg 38040
tacgaaaaaa ctttatctag ttgtttatgc ggtgctacca aaggatgttt aacattcttt 38100
tttggagaaa ctgcaactgg aaagtcgaca accaaacgtt tgttaaagtc tgctatcggt 38160
gacctgtttg ttgagacggg tcaaacaatt ttaacagatg tattggataa aggacctaat 38220
ccatttatcg ctaacatgca tttgaaaaga tctgtattct gtagcgaact acctgatttt 38280
gcctgtagtg gatcaaagaa aattagatct gacaatatta aaaagttgac agaaccttgt 38340
gtcattggaa gaccgtgttt ctccaataaa attaataata gaaaccatgc gacaatcatt 38400
atcgatacta attacaaacc tgtctttgat aggatagata acgcattaat gagaagaatt 38460
gccgtcgtgc gattcagaac acacttttct caaccttctg gtagagaggc tgctgaaaat 38520
aatgacgcgt acgataaagt caaactatta gacgaggggt tagatggtaa aatacaaaat 38580
aatagatata gattcgcatt tctatacttg ttggtgaaat ggtacaaaaa atatcatgtt 38640
cctattatga aactatatcc tacaccggaa gagattccgg actttgcatt ctatctcaaa 38700
ataggtactc tgttagtatc tagctctgta aagcatattc cattaatgac ggacctctcc 38760
aaaaagggat atatattgta cgataatgtg gttactcttc cgttgactac tttccaacag 38820
aaaatatcca agtattttaa ttctagacta tttggacacg atatagagag cttcatcaat 38880
agacataaga aatttgccaa tgttagtgat gaatatctgc aatatatatt catagaggat 38940
atttcatctc cgtaaatata tgctcatata tttatagaag atatcacata tctaaatgaa 39000
taccggaatc atagatttat ttgataatca tgttgatagt ataccaacta tattacctca 39060
tcagttagct actctagatt atctagttag aactatcata gatgagaaca gaagcgtgtt 39120
attgttccat attatgggat caggtaaaac aataatcgct ttgttgttcg ccttggtagc 39180
ttccagattt aaaaaggttt acattctagt gcctaatatt aacattttga aaatttttaa 39240
ttataatatg ggtgtagcta tgaacttgtt taatgacgaa ttcatagctg agaatatctt 39300
tattcattcc acaacaagtt tttattctct taattataac gataacgtca ttaattataa 39360
cggattatct cgctacaata actctatttt tatcgttgat gaggcacata atatctttgg 39420
gaataatact ggagaactta tgaccgtgat aaaaaataaa aacaagattc cttttttact 39480
attgtctgga tctcccatta ctaacacacc taatactctg ggtcatatta tagatttaat 39540
gtccgaagag acgatagatt ttggtgaaat tattagtcgt ggtaagaaag taattcagac 39600
acttcttaac gaacgaggtg tgaatgtact taaggatttg cttaaaggaa gaatatcata 39660
ttacgaaatg cctgataaag atctaccaac gataagatat cacggacgta agtttctaga 39720
tactagagta gtatattgtc acatgtctaa acttcaagag agagattata tgattactag 39780
acgacagcta tgttatcatg aaatgtttga taaaaatatg tataacgtgt caatggcagt 39840
attgggacaa cttaatctga tgaataattt agatacttta tttcaggaac aggataagga 39900
attgtaccca aatctgaaaa taaataatgg cgtgttatac ggagaagaat tggtaacgtt 39960
aaacattagt tccaaattta aatactttat taatcggata cagacactca acggaaaaca 40020
ttttatatac ttttctaatt ctacatatgg cggattggta attaaatata tcatgctcag 40080
taatggatat tctgaatata atggttctca gggaactaat ccacatatga taaacggcaa 40140
accaaaaaca tttgctatcg ttactagtaa aatgaaatcg tctttagagg atctattaga 40200
tgtgtataat tctcctgaaa acgatgatgg cagtcaattg atgtttttgt tttcgtcaaa 40260
cattatgtcc gaatcctata ctctgaaaga ggtaaggcat atttggttta tgactatccc 40320
agatactttt tctcaataca accaaattct tggacgatct attagaaaat tctcttacgc 40380
cgatatttct gaaccagtta atgtatatct tttagccgcc gtatattccg atttcaatga 40440
cgaagtgacg tcattaaacg attacacaca ggatgaatta attaatgttt taccatttga 40500
catcaaaaag ctgttgtatc taaaatttaa gactaaagaa acgaatagaa tatactctat 40560
tcttcaagag atgtctgaaa cgtattctct tccaccacat ccatcaattg taaaagtttt 40620
attgggagaa ttggtcagac aattttttta taataattct cgtattaagt ataacgatac 40680
caagttactt aaaatggtta catcagttat aaaaaataaa gaagacgcta ggaattacat 40740
agatgatatt gtaaacggtc acttctttgt atcgaataaa gtatttgata aatctctttt 40800
atacaaatac gaaaacgata ttattacagt accgtttaga ctttcctacg aaccatttgt 40860
ttggggagtt aactttcgta aagaatataa cgtggtatct tctccataaa actgatgaga 40920
tatataaaga aataaatgtc gagctttgtt accaatggat accttccagt tacattggag 40980
ccacacgagc tgacgttaga cataaaaact aatattagga atgccgtata taagacgtat 41040
ctccatagag aaattagtgg taaaatggcc aagaaaatag aaattcgtga agacgtggaa 41100
ttacctctcg gcgaaatagt taataattct gtagttataa acgttccgtg tgtaataacc 41160
tacgcgtatt atcacgttgg ggatatagtc agaggaacat taaacatcga agatgaatca 41220
aatgtaacta ttcaatgtgg agatttaatc tgtaaactaa gtagagattc gggtactgta 41280
tcatttagcg attcaaagta ctgctttttt cgaaatggta atgcgtatga caatggcagc 41340
gaagtcactg ccgttctaat ggaggctcaa caaggtatcg aatctagttt tgtttttctc 41400
gcgaatatcg ttgactcata aaaaagagaa tagcggtaag tataaacacg aatactatgg 41460
caataattgc gaatgtttta ttcccttcga tatatttttg ataatatgaa aaacatgtct 41520
ctctcaaatc ggacaaccat ctcataaaat agttctcgcg cgctggagag gtagttgctg 41580
ctcgtataat ctccccagaa taatatactt gcgtgtcgtc gttcaattta tacggatttc 41640
tatagttctc tgttatataa tgcggttttc catcatgatt agacgacgac aatagtgttc 41700
taaatttaga tagttgatca gaatgaatgt ttattggcgt tggaaaaatt atccatacag 41760
cgtctgcaga gtggttgata gttgttccta gatatgtaaa ataatccaac ttactaggca 41820
gcaaattgtc tagataaaat actgaatcaa acggtgcaga cgtattggtg gatctaatgg 41880
aatccaattg attaactatc ttttgaaaat atacattttt atgatccgat acttgtaaga 41940
atatagaaat aatgataagt ccatcatcgt gtttttttgc ctcttcataa gaactatatt 42000
ttttcttatt ccaatgaaca agattaatct ctccagagta tttgtacaca tctatcaagt 42060
gattggatcc ataatcgtct tcctttcccc aatatatacg tagtgatgat aacacatatt 42120
cattggggag aaaccctcca cttatatatc ctcctttaaa attaatcctt actagttttc 42180
cagtgttctg gatagtggtt ggtttcgact cattataatg tatgtctaac ggcttcaatc 42240
gcgcgttaga aattgctttt ttagtttcta tattaatagg agatagttgt tgcggcatag 42300
taaaaatgaa atgataactg tttaaaaata gctcttagta tgggaattac aatggatgag 42360
gaagtgatat ttgaaactcc tagagaatta atatctatta aacgaataaa agatattcca 42420
agatcaaaag acacgcatgt gtttgctgcg tgtataacaa gtgacggata tccgttaata 42480
ggagctagaa gaacttcatt cgcattccaa gcgatattat ctcaacaaaa ttcagattct 42540
atctttagag tatccactaa actattacgg tttatgtact acaatgaact aagagaaatc 42600
tttagacggt tgagaaaagg ttctatcaac gatatcgatc ctcactttga agagttaata 42660
ttattgggtg gtaaactaga taaaaaggaa tctattaaag attgtttaag aagagaatta 42720
aaagaggaaa gtgatgaacg tataacagta aaagaatttg gaaatgtaat tctaaaactt 42780
acaacacggg ataaattatt taataaagta tatataagtt attgcatggc gtgttttatt 42840
aatcaatcgt tggaggattt atcgcatact agtatttaca atgtagaaat tagaaagatt 42900
aaatcattaa atgattgtat taacgacgat aaatacgaat atctgtctta tatttataat 42960
atgctagtta atagtaaatg aacttttaca gatctagtat aattagtcag attattaagt 43020
ataatagacg actagctaag tctattattt gcgaggatga ctctcaaatt attacactca 43080
cggcattcgt taaccaatgc ctatggtgtc ataaacgagt atccgtgtcc gctattttat 43140
taactactga taacaaaata ttagtatgta acagacgaga tagttttctc tattctgaaa 43200
taattagaac tagaaacatg tctagaaaga aacgattatt tctgaattat tccaattatt 43260
tgtccaaaca ggaaagaagt atactatcgt catttttttc tctagatcca gctactactg 43320
ataatgatag aatagatgct atttatccgg gtggcatacc caaaaggggt gagaatgttc 43380
cagagtgttt atccagggaa attaaagaag aagttaatat agacaattct tttgtattca 43440
tagacactcg gttttttatt catggcatca tagaagatac cattattaat aaattttttg 43500
aggtaatctt ctttgtcgga agaatatctt taacgagtga tcaaatcatt gatacattta 43560
aaagtaatca tgaaatcaag gatctaatat ttttagatcc gaattcaggt aatggactcc 43620
aatacgaaat tgcaaaatat gctctagata ctgcaaaact caaatgttat ggccatagag 43680
gatgttatta cgaatcatta aaaaaattaa ctgaggatga ttgattagaa aatataaatt 43740
aatttaccat cgtgtatttt tataacggga ttgtccggca tatcatgtag atagttaccg 43800
tctacatcgt atactcgacc atctacgcct ttaaatcctc tatttattga cattaatcta 43860
ttagaattgg aataccaaat attagtaccc tcaattagtt tattggtaat atttttttta 43920
gacgatagat cgatggctct tgaaaccaag gttttccaac cggactcatt gtcgatcggt 43980
gagaagtctt tttcattagc atgaatccat tctaatgatg tatgtttaaa cactctaaac 44040
aattggacaa attcttttga tttgctttga atgatttcaa ataggtcttc gtctacagta 44100
ggcataccat tagataatct agccattata aagtgcacgt ttacatatct acgttctgga 44160
ggagtaagaa cgtgactatt gagacgaatg gctcttccta ctatctgacg aagagacgcc 44220
tcgttccatg tcatatctaa aatgaagata tcattaattg agaaaaaact aataccctcg 44280
cctccactag aagagaatac gcatgtttta atgcattctc cgttagtgtt tgattcttgg 44340
ttaaactcag ccaccgcctt gattctagta tcttttgttc tagatgagaa ctctatatta 44400
gagataccaa agactttgaa atatagtaat aagatttcta ttcctgactg attaacaaat 44460
ggttcaaaga ctagacattt accatgggat gctaatattc ccaaacatac atctataaat 44520
ttgacgcttt tctcttttaa ttcagtaaat agagagatat cagccgcact agcatcccct 44580
ttcaatagtt ctcccttttt aaaggtatct aatgcggatt tagaaaactc tctatctctt 44640
aatgaatttt taaaatcatt atatagtgtt gctatctctt gcgcgtattc gcccggatca 44700
cgattttgtc tttcaggaaa gctatcgaac gtaaacgtag tagccatacg tctcagaatt 44760
ctaaatgatg atatacctgt ttttatttca gcgagtttag ccttttgata aatttcttct 44820
tgctttttcg acatattaac gtatcgcatt aatactgttt tcttagcgaa tgatgcagac 44880
ccttctacgt catcaaaaat agaaaactcg ttattaacta tgtacgaaca taggcctcct 44940
agtttggaga ctaattcttt ctcatcaact agacgtttat tctcaaatag cgattggtgt 45000
tgtaaggatc ctggtcgtag taagttaacc aacatggtga attcttgcac actattaacg 45060
ataggtgtag ccgataaaca aatcatctta tggtttttta atgcgatggt cttagataaa 45120
aaattatata ctgaacgagt aggacggatc ttaccatctt ctttgattaa tgatttagaa 45180
atgaagttat gacattcatc aataatgacg catattctac tcttggaatt aatagttttg 45240
atattagtaa aaaatttatt tctaaaattt tgatcatcgt aattaataaa aatacaatcc 45300
ttcgttatct ctggagcgta tctgagtata gtgttcatcc aaggatcttc tatcaaagcc 45360
tttttcacca ataagataat agcccaattc gtataaatat ccttaagatg tttgagaata 45420
tatacagtag tcattgtttt accaacaccc gtttcatgga acaataaaag agaatgcata 45480
ctgtctaatc ctaagaaaac tcttgctaca aaatgttgat aatccttgag gcgtactacg 45540
tctgttccca tcatttcaac aggcatatta gtagttctgc gcaatgcata atcgatatag 45600
gccgcgtgtg atttactcat ttatgagtga taagtaataa ctatgtttta aaaatcacag 45660
cagtagttta actagtcttc tctgatgttt gttttcgata ctttttgaat cagaagtcat 45720
actagaataa agcaacgagt gaacgtaata gagagcttcg tatactctat tcgaaaactc 45780
taagaactta ttaatgaatt ccgtatccac tggattgttt aaaatactaa attgaacact 45840
gttcacatcc ttccaagaag aagacttagt gacggactta acatgagaca taaataaatc 45900
caaatttttt ttacaaacat cactagccac cataatggcg ctatctttca accagctatc 45960
gcttacgcat tttagcagtc taacattttt aaagagacta caatatattc tcatagtatc 46020
gattacacct ctaccgaata aagttggaag tttaataata caatattttt cgtttacaaa 46080
atcaaataat ggtcgaaaca cgtcgaaggt taacatctta taatcgctaa tgtatagatt 46140
gttttcagtg agatgattat tagatttaat agcatctcgt tcacgtttga acagtttatt 46200
gtgtgcgctg aggtcggcaa ctacggcgtc cgctttagta ctcctcccat aatactttac 46260
gctattaatc tttaaaattt catagacttt atctagatcg ctttctggta acatgatatc 46320
atgtgtaaaa agttttaaca tgtcggtcgg cattctattt agatcattaa ctctagaaat 46380
ctgaagaaag taattagctc cgtattccag actaggtaat gggcttttac ctaaagacaa 46440
gttaagttct ggcaatgttt cataaaatgg aagaaggaca tgcgttccct cccggatatt 46500
ttttacaatt tcatccattt acaactctat agtttgtttt cattattatt agttattatc 46560
tcccataatc ttggtaatac ttaccccttg atcgtaagat accttataca ggtcattaca 46620
tacaactacc aattgttttt gtacataata gattggatgg ttgacatcca tggtggaata 46680
aactactcga acagatagtt tatctttccc cctagataca ttggccgtaa tagttgtcgg 46740
cctaaagaat atctttggtg taaagttaaa agttagggtt cttgttccat tattgctttt 46800
tgtcagtagt tcattataaa ttctcgagat gggtccgttc tctgaatata gaacatcatt 46860
tccaaatcta acttctagtc tagaaataat atcggtctta ttcttaaaat ctattccctt 46920
gatgaaggga tcgttaatga acaaatcctt ggcctttgat tcggctgatc tattatctcc 46980
gttatagacg ttacgttgac tagtccaaag acttacagga atagatgtat cgatgatgtt 47040
gatactatgt gatatgtgag caaagattgt tctcttagtg gcatcactat atgttccagt 47100
aatggcggaa aactttttag aaatgttata tataaaagaa ttttttcgtg ttccaaacat 47160
tagcagatta gtatgaagat aaacactcat attatcagga acattatcaa tttttacata 47220
cacatcagca tcttgaatag aaacgatacc atcttctgga acctcaacaa tctcggcaga 47280
ctccggataa ccagtcggtg ggccatcact aacaataact agatcatcca acaatctact 47340
cacatatgca tctatataat ctttttcatc ttgtgagtac cctggatacg aaataaattt 47400
attatccgta tttccataat aaggtttagt ataaacagag agcgatgttg ccgcatgaac 47460
ttcagttaca gtcgccgttg gttggtttat ttgacctatt actctcctag gtttctctat 47520
aaacgatggt ttaatttgta cattcttaac catatatcca ataaagctca attcaggaac 47580
ataaacaaat tctttgttga acgtttcaaa gtcgaacgaa gagtcacgaa taacgatatc 47640
ggatactgga ttgaaggtta ccgttacggt aatttttgaa tcggatagtt taagactgct 47700
gaatgtatct tccacatcaa acggagtttt aatataaacg tatactgtag atggttcttt 47760
aatagtgtca ttaggagtta ggccaataga aatatcatta agttcactag aatatccaga 47820
gtgtttcaaa gcaattgtat tattgataca attattatat aattcttcgc cctcaatttc 47880
ccaaataaca ccgttacacg aagagataga tacgtgatta atacatttat atccaacata 47940
tggtacgtaa ccgaatcttc ccataccttt aacttctgga agttccaaac tcagaaccaa 48000
atgattaagc gcagtaatat actgatccct aatttcgaag ctagcgatag cctgattgtc 48060
tggaccatcg tttgtcataa ctccggatag agaaatatat tgcggcatat acaaagttgg 48120
aatttgacta tcgactgcga agacattaga ccgtttaata gagtcatccc caccgatcaa 48180
agaattaatg atagtattat tcattttcta tttaaaatgg aaaaagctta caataaactc 48240
cgtagagaaa tatctataat ttgtgagttt tccttaaagt aacagcttcc gtaaacgccg 48300
tctttatctc ttagtaggtt tattgtattt atgacctttt ccttatcttc atagaatact 48360
aaaggcaaca aagaaatttt tggttcttct ctaagagcta cgtgagactt aaccatagaa 48420
gccaacgaat ccctacatat tttagaacag aaatacccaa cttcaccacc cttgaatgtc 48480
tcaatactaa taggtctaaa aaccaaatct tgattacaaa accaacactt atcaattaca 48540
ctatttgtct taatagacac atctgccata gatttataat actttggtag tatacaagcg 48600
agtgcttctt ctttagcggg cttaaagact gctttaggtg ctgaaataac cacatctgga 48660
aggcttactc gcttagccat ttaattacgg aactattttt ttatacttct aatgagcaag 48720
tagaaaacct ctcatctaca aaaacatact cgtgtccata atcctctacc atagttacac 48780
gttttttaga tctcatatgt gctaaaaagt tttcccatac taattggtta ctattatttt 48840
tcgtataatt tttaacagtt tgaggtttta gatttttagt tacagaagtg atatcgaata 48900
ttttatccaa aaagaatgaa taattaattg tcttagaagg agtgttttct tggcaaaaga 48960
ataccaagtg cttaaatatt tctactactt cattaatctt ttctgtactc agattcagtt 49020
tctcatcttt tacttgattg attatttcaa agactaactt ataatccttt ttatttattc 49080
tctcgttagc cttaagaaaa ctagatacaa aatttgcatc tacatcatcc gtggatattt 49140
gatttttttc catgatatcc aagagttccg agataatttc tccagaacat tgatgagaca 49200
ataatctccg caatacattt ctcaaatgaa taagtttatt agacacatgg aagtttgact 49260
ttttttgtac ctttgtacat ttttgaaata cagactcgca aaaaatacaa tattcatatc 49320
cttgttcaga tactataccg ttgtgtctac aaccgctaca taatcgtaga ttcatgttaa 49380
cactctacgt atctcgtcgt ccaatatttt atataaaaac attttatttc tagacgttgc 49440
cagaaaatcc tgtaatattt ttagtttttt gggctgtgaa taaagtatcg ccctaatatg 49500
gttaccgtcc tccgccaata tagtagttaa attatccgca catgcagaag aacaccgctt 49560
aggcggattc agtacaatgt tatatttttc gtaccaactc atttaaatat cataatctaa 49620
aatagttctg taatatgtct agcgctaata tattgatcat aatcctgtgc ataaattaag 49680
atacaacaat gtctcgaaat catcgacatg gcttcttcca tagttagaag atcgtcgtca 49740
aagttagcaa cgtgattcat caacatttgc tgttttgagg cagcaaatac tgaaccgtcg 49800
ccattcaacc attcataaaa accatcgtct gaatccattg ataatttctt gtactggttt 49860
ttgagagctc gcatcaatct agcatttcta gctcccggat tgaaaacaga aagaggatcg 49920
tacatccagg gtccattttc tgtaaataga atcgtataat gtcccttcaa gaagatatca 49980
gacgatccac aatcaaagaa ttggtctccg agtttgtaac aaactgcgga ctttaaccta 50040
tacatgatac cgtttagcat gatttctggt gatacgtcaa tcggagtatc atctattaga 50100
gatctaaagc cggtgtaaca ttctccacca aacatattct tattctgacg tcgttctaca 50160
taaaacatca ttgctccatt aacgataaca ggggaatgaa cagcactacc catcacatta 50220
gttcccaatg gatcaatgtg tgtaactcca gaacatcttc catatcctat gttaggagga 50280
gcgaacacca ctcttccact attgccatcg aatgccatag aataaatatc cttggaattg 50340
atagaaatcg gactgtcgga tgttgtgatc atcttcatag gattaacaac tatgtatggt 50400
gccgcctgaa gtttcatatc gtaactgatg ccgtttatag gtctagccac agaaaccaac 50460
gtaggtctaa atccaactat agacaaaata gaagccaata tctgttcttc atctgtcata 50520
acttgagagc atccagtatg aataatcttc attagatggg gatctaccgc atcatcatcg 50580
ttacaataaa aaattcccat tctaatgttc ataattgctt ttctaatcat ggtatgcatg 50640
tttgctctct gaatctctgt ggaaattaga tctgatacac ctgtaatcac tatcggatta 50700
tcctccgtaa gacgattaac caacaacata taattataag actttacttt tctaaattca 50760
taaagttgct ggattaggct ataggtgtct ccatgtacat acgcgttctc gagcgcagga 50820
agtttaatac cgaatagtgc catcagaata ggatgaatat agtaattagt ttctggtttt 50880
ctataaataa aagacaaatc ttgtgaacta gacatatcgg taaaatgcat ggattggaat 50940
cgtgtagtcg acagaagaat atgatgatta gatggagagt atattttatc taactctttg 51000
agttggtcac cgattctagg actagctcga gaatgaataa gtactaaagg atgagtacat 51060
ttcacagaaa cactagcatt gttcaatgtg ctctttacat gggtaaggag ttgaaatagc 51120
tcgtttctat ttgttctgac aatatttagt ttattcataa tgttaagcat atcctgaata 51180
gtaaagttag atgtgtcata cttgttagta gttagatatt tagcaattgc attcccatca 51240
tttctcaatc tcgtactcca atcatgcgtg gatgctactt cgtcgatgga aaccatacaa 51300
tcctttttga taggctgttg agattgatta tttcctgcac gtttaggttt ggtacgttga 51360
tttctagccc ctgcggatat aaagtcatcg tctacaattt tggataatga attgcataca 51420
ctacaagaca aagatttatc agaagtgtga atatgatctt catctaccaa agaaagagtt 51480
tgattagtat aactagattt tagtcctgcg ttagatgtta aaaaaacatc gctattgacc 51540
acggcttcca ttatttatat tcgtagtttt tactcgaaag cgtgatttta atattcaatc 51600
ttattacttt tggaatcgtt caaaaccttt gactaattgt agaatttgat ctattgccct 51660
acgcgtatac tcccttgcat catatacgtt cgtcaccaga tcgtttgttt cggcctgaag 51720
ttggtgcata tctctttcaa cattcgacat gagatcctta agggccatat cgtctagatt 51780
ttgttgagat gctgctcctg gatttggatt ttgttgtgct gttgtacata ctgtaccacc 51840
agtaggtgta ggagtacata cagtggccac aataggaggt tgaggaggtg taaccgttgg 51900
agtagtacaa gaaatacttc catccgattg ttgtgtacat gtagttgttg gtaacgtctg 51960
agaaggttgg gtagatggcg gcgtcgtcgt cttttgatct ttattaaatt tagagataat 52020
atcctgaaca gcattgctcg gcgtcaacgc tggaaggagt gaactcgccg gcgcatcagt 52080
atctgcagac agccaatcaa aaagattaga catatcagat gatgtattag tttgttgtcg 52140
tggttttggt gtaggagccg gtgtagctgt tggaaccggc tgtggagtta tatgaatagt 52200
tggttgtagc ggttggatag gctgtctgct ggcggccatc atattatctc tagctagttg 52260
ttctcgcaac tgtctttgat aatacgactc ttgagacttt agtcctattt caatcgcttc 52320
atcctttttc gtatccggat ccttttcttc agaataatag attgacgact ttggtgtaga 52380
ggattctgcc agcccctgtg agaacttgtt aaagaagtcc atttaaggct ttaaaattga 52440
attgcgatta taagattaaa tggcagacac agacgatatt atcgactatg aatccgatga 52500
tctcaccgaa tacgaggatg atgaagaaga ggaagaagat ggagagtcac tagaaactag 52560
tgatatagat cccaaatctt cttataagat tgtagaatca gcatccactc atatagaaga 52620
tgcgcattcc aatcttaaac atatagggaa tcatatatct gctcttaaac gacgctatac 52680
tagacgtata agtctatttg aaatagcggg tataatagca gaaagctata acttgcttca 52740
acgaggaaga ttacctctag tttcagaatt ttctgacgaa acgatgaagc aaaatatgct 52800
acatgtaatt atacaagaga tagaggaggg ttcttgtcct atagtcatcg aaaagaacgg 52860
agaattgttg tcggtaaacg attttgacaa agatggtcta aaattccatc tagactatat 52920
tatcaaaatt tggaaacttc aaaaacgata ttagaattta tacgaatatc gttctctaaa 52980
tgtcacaatc aagtctcgca tgttcagcaa tttattgtcg tactttatat cgtgttcatt 53040
aacgatatct tgcaaaatag taatgattct atcttccttc gatagatatt cttcagagat 53100
tattgtctta tattctttct tgttatcaga tatgaatttg ataagacttt gaacattatt 53160
gatacccgtc tgtttaattt tttctacaga tattttagtt ttggcagatt ctatcgtatc 53220
tgtcaataga catccaacat cgacattcga cgtcaattgt ctataaatca acgtataaat 53280
tttagaaata acattagcga attgttgtgc attgatgtcg ttattctgaa acagtatgat 53340
tttaggtagc attttcttaa caaagagaac gtatttattg ttactcagtt gaacagatga 53400
tatatccaga ttactaacgc atctgattcc atataccaaa ctttcagaag aaatggtgta 53460
caattgtttg tattcattca atgtctcttt ttcagaaatt agtttagagt cgaatactgc 53520
aataattttc aagagatagt tttcatcaga taagatttta tttagtgtag atatgataaa 53580
actattgttt tgttggagaa cttgatacgc cgcgttctct gtagtcgacg ctctcaaatg 53640
ggaaacaatc tccattattt ttttggaatc ggatacaata tcttcggtat cttgacgcaa 53700
tctagtatac atagagttaa gagaaattag agtttgtaca ttaagcaaca tgtctctaaa 53760
tgtggctgca aacttttcct tttccacatc atctagttta ttatataccg atttcacaac 53820
ggcaccagat ttaaggaacc agaatgaaaa actctgataa ctacaatatt tcatcatagt 53880
tacgatttta tcatcttcta tagttggtgt aatagcgcat acctttttct ccaagactgg 53940
aaccaacgtc ataaaaatgt ttaaatcaaa atccatatca acatctgatg cgctaagacc 54000
agtctcgcgt tcaagattat ctttactaat ggtgacgaac tcatcgtata gaactctaag 54060
tttgtccatt atttatttac agatttagtt gtttaattta tttgtgctct tccagagttg 54120
ggatagtatt tttctaacgt cggtattata ttattaggat ctacgttcat atgtatcata 54180
atattaatca tccacgtttt gataaatcta tctttagctt ctgaaataac gtatttaaac 54240
aaaggagaaa aatatttagc tacggcatca gacgcaataa cattttttgt aaatgtaacg 54300
tatttagacg acagatcttc gttaaaaagt tttccatcta tgtagaatcc atcggttgtt 54360
aacaccattc ccgcgtcaga ttgaatagga gtttgaatag tttgttttgg aaatagatcc 54420
ttcaataact tatagttggg tgggaaaaaa tcgattttat cactagactc tttctttttt 54480
actatcatta cctcatgaac tatttcttga atgagtatat gtattttctt tcctatatcg 54540
gacgcgttca ttggaaaata taccatgtcg ttaactataa gaatattttt atcctcgttt 54600
acaaactgaa taatatcaga tgtagttcgt aaacgaacta tatcatcacc agcacaacat 54660
ctaactatat gatatccact agtttccttt agtcgtttat tatcttgttc catattagca 54720
gtcattccat catttaagaa ggcgtcaaag ataataggga gaaatgacat tttggattct 54780
gttacaactt taccaaaatt aaggatatac ggacttacta tctttttctc aacgtcgatt 54840
tgatgaacac acgatgaaaa tgtacttcga tgagattgat catgtagaaa acaacaaggg 54900
atacaatatt tccacatatc atgaaatata ttaagaaatc ccaccttatt atatttcccc 54960
aaaggatcca tgcatgtaaa cattatgccg ttatcattaa taaagacttc tttctcatcg 55020
gatctgtaaa agttgttact gatttttttc attccaggat ctagataatt aataatgatg 55080
ggttttctat tcttattctt tgtattttgg catatcctag accagtaaac agtttccact 55140
ttggtaaaat cagcagactt ttgaacgcta ttaaacatgg cattaatggc aataactaaa 55200
aatgtaaaat atttttctat gttaggaata tggtttttca ctttaataga tatatggttt 55260
ttggccaaaa tgatagatat ttttttatcc gaggatagta aaatattatt agtcgccgtc 55320
tctataaaaa tgaagctagt ctcgatatcc aattttattc tagaattgat aggagtcgcc 55380
aaatgtacct tatacgttat atctcccttg atgcgttcca tttgtgtatc tatatcggac 55440
acaagatctg taaatagttt tacgttatta atcatcacgg tatcgccgtc gctagataac 55500
gctaatgtac catccaagtc ccaaatggag agatttaact gttcatcgtt tagaataaaa 55560
tgattaccgg tcatattaat aaagtgttca tcgtatctag ataacaacga cttataatta 55620
atgtccaagt cttgaactcg ctgaatgatc ttttttaacc cagttagttt tagattggta 55680
cgaaatatat tgttaaactt tgattctaca gtaatgtcca aatctagttg tggaaatact 55740
tccatcaaca ttgtttcaaa cttgataata ttattatcta catcttcata cgatccaaat 55800
tccggaatag atgtatcgca cgctctggcc acccagataa ccaaaaagtc acacgctcca 55860
ggatatacat tgtataaaaa gctatcgttt tttagtagtg tttttttctg agtatatacg 55920
aagggattaa aaatagtatt atcaacgtaa ctatattcca aattattctt atgagaatag 55980
ataataatat cgtccttaat atctaacaaa tttcctaaat atccctttaa ttgagtcatt 56040
cgaagcgtca atagaatatg tctcttaact atttccggct gttgtatatt taaatgactt 56100
cgtaaaaaat aatatatggg cgacttctca tctatgtaat catatggagt gagatatagg 56160
gctcgttcta cctcctgccc cttacccacc tgtaatacca attgcggact tactatatat 56220
cgcatattta tatcgtgggg taaagtgaaa atctactacc gatgatgtaa gtcttacaat 56280
gttcgaacca gtaccagatc ttaatttgga ggcctccgta gaactagggg aggtaaatat 56340
agatcaaaca acacctatga taaaggaaaa tagcggtttt atatcccgta gtagacgtct 56400
attcgcccat agatctaagg atgatgagag aaaactagca ctacgattct ttttacaaag 56460
actttatttt ttagatcata gagagattca ttatttgttc agatgcgttg acgctgtaaa 56520
agacgtcact attaccaaaa aaaataacat tatcgtggcg ccttatatag cacttttaac 56580
tatcgcatca aaaggatgca aacttacaga aacaatgatt gaagcattct ttccagaact 56640
atataatgaa catagtaaga aatttaaatt caactctcaa gtatccatca tccaagaaaa 56700
actcggatac cagtttggaa actatcacgt ttatgatttt gaaccgtatt actctacagt 56760
agctctggct attcgagatg aacattcatc tggcattttt aatatccgtc aagagagtta 56820
tctggtaagt tcattatctg aaataacata tagattttat ctaattaatc taaaatctga 56880
tcttgttcaa tggagtgcta gtacgggcgc tgtaattaat caaatggtaa atactgtatt 56940
gattacagtg tatgaaaagt tacaactggt catagaaaat gattcacaat ttacatgttc 57000
attggctgtg gaatcaaaac ttccaataaa attacttaaa gatagaaatg aattatttac 57060
aaaattcatc aacgagttaa aaaagaccag ttcattcaag ataagcaaac gcgataagga 57120
tacgctacta aaatatttta cttaggactg gagttagaat ttatagacga ctcatttcgt 57180
ttatcattat tagtattctt cttgttatct tgttcagaaa tatacagcaa tgctatgcct 57240
aatactaaat acattatcat gcttgcaatg gctctaacaa cgacgaacca aaatgaattt 57300
ggtcgtagct tttgttcaca aaaatacata aagaaatgtc tacataaatc tatggcgcca 57360
ttggctactt gaaatagcgc cagtcctcct acagatttta atatagctgt ataacatgac 57420
atttattcat catcaaaaga gacagagtca ccatctgtca tatttagatt ttttttcatg 57480
tgttcaaagt atcctctact catttcatta taatagttta tcatacttag aattttagga 57540
cggatcaatg agtaagactt gactagatcg tcagtagtaa tttgtgcatc gtctattctg 57600
catccgcttc gtcgaataat gtatagcatc gctttgagat tctccatagc tatcaagtct 57660
ttatacaatg acatggaaat atctgtgaat actttatact tctccaacat cgatgcctta 57720
acatcatcgc ctactttagc attgaaaata cgttctattg tgtagatgga tgtagcaaga 57780
tttttaaaca acaatgccat tttacacgat gattgcctca agtctccaat cgtttgttta 57840
gaacgattag ctacagagtc caatgcttgg ctgactagca tattattatc tttagaaatt 57900
gtattcttca atgaggcgtt tatcatatct gtgatttcgt tagtcatatt acagtctgac 57960
tgggttgtaa tgttatccaa catatcacct atggatacgg tacacgtacc agcatttgta 58020
ataatcctat ctaagatgtt gtatggcatt gcgcagaaaa tatcttctcc tgtaatattt 58080
ccactctcga taaatctact cagattattc ttaaatgcct tattctctgg agaaaagata 58140
tcagtgtcca tcatttcatt aatagtatac gcagaaaaga taccacgagt atcaattcta 58200
tccaagatac ttatcggttc cgagtcacag ataatggttt cctctccttc gggagatcct 58260
gcatagaaat atctaggaca atagtttcta tactgtctgt aactctgata atctctaaag 58320
tcactaactg ataccatgaa attgagaaga tcaaacgctg aagtaattaa tttttctgcc 58380
tcgtttttac tacaactagt tttcatcaat gtagtgacga tgtattgttt agttactctt 58440
ggtctaatac tgatgataga gatattatta cttcccataa tggatcttct agtagtcacc 58500
ttaaagccca ttgatgcaaa tagcagatag ataaagtctt ggtatgactc ctttctaata 58560
tagtacggac tacctttgtc acccaacttt atacccacat aagccataac aacctcttta 58620
atagccgttt catgaggttt atcagccatg agcctgagta gttggaagaa tctcatgaat 58680
cctgtctcag aaagtcctat atgcatgata gatttatctt tcctgggaaa ctctcgtata 58740
gtcatagatg aaatactctt caaagtttct gaaataagat tagtaacagt cttacctccg 58800
actactctag gtaacaaaca aactctaata ggtgttttct ctgcggagat aatatcagaa 58860
aggatagagc aataagtagt attattgtga ttataaagac cgaatacata acaggtagaa 58920
tttataaaca tcatgtcctg aaggttttta gacttgtatt cctcgtaatc cataccgtcc 58980
caaaacatgg atttggtaac tttgatagcc gtagatcttt gttccttcgc caacaggtta 59040
aagaaattaa taaagaattt gtggtttcta cctatgtcta caaattgcac gtttggaagc 59100
gccacggtta cattcactgc agcattttga ggatcgcgag tatgaagtac gatgttattg 59160
tttactggta tatctggaaa gaattctacc agtctaggaa taagagattg atatcgcata 59220
gaaatacaaa agttcataat ctcatcatct aagagcattt tgttaccatt gtaataaata 59280
tccactctgt catatgtata aatgaagtac tgttcaaaca tgatgagatg tttatatgtt 59340
ggcatagtag tgagatctac gtttggtaat ggcaatgtat taagattaac tccataatgt 59400
ctagcagcat ctgcgatgtt ataagcgttg tcaaagcggg gtcgatcttg tgctgttata 59460
tattgtctaa cacctataag attatcaaaa tcttgtctgc ttaatacacc gttaacaatt 59520
tttgccttga attcttttat tggtgcatta ataacatcct tatagaggat gttaaacaaa 59580
taagtgttat caaagttaag atctggatat ttcttttctg ctagaacatc cattgagtcg 59640
gagccatctg gtttaatata accaccgata aatctagctc tgtattctgt atccgtcaat 59700
ctaatattaa gaaggtgttg agtgaaaggt ggaagatcgt aaaagctgtg agtattaatg 59760
ataggattag tttccgaact aatgttaatt ggggtattaa taatatctat atttccagcg 59820
ttaagtgtaa cattaaacag ttttaattca cgtgacgtgg tatcaattaa ataattaatg 59880
cccaatttgg atatagcagc ctgaagctca tcttgtttag ttacggatcc taatgagtta 59940
ttaagcaata tatcgaacgg atgaacgaag gttgttttaa gttggtcaca tactttgtaa 60000
tctagacata gatgcggaag aacggtagaa actatacgaa ataaatattc agagtcctct 60060
aattgatcaa gagtaactat tgacttaata ggcatcattt atttagtatt aaatgacgac 60120
cgtaccagtg acggatatac aaaacgattt aattacagag ttttcagaag ataattatcc 60180
atctaacaaa aattatgaaa taactcttcg tcaaatgtct attctaactc acgttaacaa 60240
cgtggtagat agagaacata atgccgccgt agtgtcatct ccagaggaaa tatcctcaca 60300
acttaatgaa gatctatttc cagatgatga ttctccggcc actattatcg aacgagtaca 60360
acctcatact actattattg acgatactcc acctcctacg tttcgtagag agttattgat 60420
atcggaacaa cgtcaacaac gagaaaaaag atttaatatt acagtatcga aaaatgctga 60480
agcaataatg gaatctagat ctatgatatc ttctatgcca acacaaacac catccttggg 60540
agtagtttat gataaagata aaagaattca gatgttggag gatgaagtgg ttaatcttag 60600
aaatcaacga tctaatacaa aatcatctga taatttagat aattttacca gaatactatt 60660
tggtaagact ccgtataaat caacagaagt taataagcgt atagccatcg ttaattatgc 60720
aaatttgaac gggtctccct tatcagtcga ggacttggat gtttgttcag aggatgaaat 60780
agatagaatc tataaaacga ttaaacaata tcacgaaagt agaaaacgaa aaattatcgt 60840
cactaacgtg attattattg tcataaatat tatcgagcaa gcattgctaa aactcggatt 60900
tgaagaaatc aaaggactga gtaccgatat cacttcagaa attatcgatg tggagatcgg 60960
agatgactgc gatgctgtag catcaaaact aggaatcggt aacagtccgg ttcttaatat 61020
tgtattgttt atactcaaga tattcgttaa acgaattaaa attatttaat ttaatacatt 61080
cccatatcca gacaacaatc gtctggatta atctgttcct gtcgtctcat accggacgac 61140
atattaatct ttttattagt aggcatcttt ttagatggtt tctttttccc agcattaact 61200
gagtcgatac ctagaagatc gtgattgatc tctccgacca ttccacgaac ttctaattgg 61260
ccgtctctga cggtaccata aactatttta ccagcattag taacagcttg gacaatctga 61320
ccatccatcg cattgtacga tgtagtagta actgttgttc tacgtctagg agcaccagaa 61380
gtatttttgg agcccttgga tgttgatgta gaagaagacg aggattttga ttttggttta 61440
catgtaatac attttgtatc acatgcgccg gcagtcacat ctgtttgaga attaagatta 61500
ttgttgcctc ctttgacggc tgcatctcca ccgatttgcg ctagtagatt tttaagctgt 61560
ggtgtaatct tattaactgt ttcgatataa tcatcgtaac tgcttctaac ggctaaattt 61620
tttttatccg ccatttagaa gctaaaaata tttttattta tgcagaagat ttaactagat 61680
tatacaatga actaatatga tccttttcca gattatttac aaacttggta ttttttggtt 61740
ctggaggagg cgaatttaaa ttcggacttg gatttggatt ttgtgggttc ttgatcttat 61800
tatacagcgc atataggatg gcgacggtaa ctgctacgca aataccgatc aacaaaagaa 61860
taccaatcat ttattgacaa taacttcact attgatcaag tatgcaatat atcatctttt 61920
cactaaataa gtagtaataa tgattcaaca atgtcgagat atatggacga taataattta 61980
gttcatggaa atatcgctat gattggtatg aatgactccg ctaactctgt ggggcgcgca 62040
gtgctttccc cacatagaat aaattagcat tccgactgtg ataataatac caagtataaa 62100
cgccataata ctcaatactt tccatgtacg agtgggactg gtagacttac taaagtcaat 62160
aaaggcgaag atacacgaaa gaatcaaaag aatgattcca gcgattagca cgccggaaaa 62220
ataatttcca atcataagca tcatatccat ttaactaata aaaattttaa atcgccgaat 62280
gaacaaagtg gaatataaac catataaaaa caatagtttg tactgcaaaa ataatatcta 62340
tttttgtttt cgaagatatg gtaaaattaa atagtagtac acagcatgtt ataactaaca 62400
gcagcaacgg ctcgtaatta cttatcattt actagacgaa aaggtggtgg gatattttct 62460
tgctcaaata atacgaatat atcacccatc cattttatgc gatgtttata tactctaatc 62520
tttaatagat ctatagacga cgggtttacc aacaatatag attttatcga ttcatctaat 62580
ttaaaccctt ccttaaacgt gaatgatcta ttatctggca taacgatgac tctacccgat 62640
gaatcggaca atgtactggg ccatgtagaa taaattatca acgaattatc gtctacgaac 62700
atttatatca tttgttttaa ttttagtacg cgaataaata gatataaaat agaaaataac 62760
agatattaca accaatgtta tggccgcgcc cggccggccg cggccgcttt ttttctagac 62820
actaaataaa tagtaagatt aaattaatta taaaattatg tatataatat taattataaa 62880
attatgtata tgatttacta actttagtta gataaattaa taatacataa attttagtat 62940
attaatatta taaattaata atacataaat tttagtatat taatattata ttttaaatat 63000
ttatttagtg tctagaaaaa aaggcctagc aggcc 63035
<210> 14
<211> 62068
<212> DNA
<213> 人工序列
<220>
<223> sMVA片段3
<400> 14
ggcctagcag gccttttttt ctagacacta aataaatagt aagattaaat taattataaa 60
attatgtata taatattaat tataaaatta tgtatatgat ttactaactt tagttagata 120
aattaataat acataaattt tagtatatta atattataaa ttaataatac ataaatttta 180
gtatattaat attatatttt aaatatttat ttagtgtcta gaaaaaaagg ccggccgggt 240
attaataata tctatatttc cagcgttaag tgtaacatta aacagtttta attcacgtga 300
cgtggtatca attaaataat taatgcccaa tttggatata gcagcctgaa gctcatcttg 360
tttagttacg gatcctaatg agttattaag caatatatcg aacggatgaa cgaaggttgt 420
tttaagttgg tcacatactt tgtaatctag acatagatgc ggaagaacgg tagaaactat 480
acgaaataaa tattcagagt cctctaattg atcaagagta actattgact taataggcat 540
catttattta gtattaaatg acgaccgtac cagtgacgga tatacaaaac gatttaatta 600
cagagttttc agaagataat tatccatcta acaaaaatta tgaaataact cttcgtcaaa 660
tgtctattct aactcacgtt aacaacgtgg tagatagaga acataatgcc gccgtagtgt 720
catctccaga ggaaatatcc tcacaactta atgaagatct atttccagat gatgattctc 780
cggccactat tatcgaacga gtacaacctc atactactat tattgacgat actccacctc 840
ctacgtttcg tagagagtta ttgatatcgg aacaacgtca acaacgagaa aaaagattta 900
atattacagt atcgaaaaat gctgaagcaa taatggaatc tagatctatg atatcttcta 960
tgccaacaca aacaccatcc ttgggagtag tttatgataa agataaaaga attcagatgt 1020
tggaggatga agtggttaat cttagaaatc aacgatctaa tacaaaatca tctgataatt 1080
tagataattt taccagaata ctatttggta agactccgta taaatcaaca gaagttaata 1140
agcgtatagc catcgttaat tatgcaaatt tgaacgggtc tcccttatca gtcgaggact 1200
tggatgtttg ttcagaggat gaaatagata gaatctataa aacgattaaa caatatcacg 1260
aaagtagaaa acgaaaaatt atcgtcacta acgtgattat tattgtcata aatattatcg 1320
agcaagcatt gctaaaactc ggatttgaag aaatcaaagg actgagtacc gatatcactt 1380
cagaaattat cgatgtggag atcggagatg actgcgatgc tgtagcatca aaactaggaa 1440
tcggtaacag tccggttctt aatattgtat tgtttatact caagatattc gttaaacgaa 1500
ttaaaattat ttaatttaat acattcccat atccagacaa caatcgtctg gattaatctg 1560
ttcctgtcgt ctcataccgg acgacatatt aatcttttta ttagtaggca tctttttaga 1620
tggtttcttt ttcccagcat taactgagtc gatacctaga agatcgtgat tgatctctcc 1680
gaccattcca cgaacttcta attggccgtc tctgacggta ccataaacta ttttaccagc 1740
attagtaaca gcttggacaa tctgaccatc catcgcattg tacgatgtag tagtaactgt 1800
tgttctacgt ctaggagcac cagaagtatt tttggagccc ttggatgttg atgtagaaga 1860
agacgaggat tttgattttg gtttacatgt aatacatttt gtatcacatg cgccggcagt 1920
cacatctgtt tgagaattaa gattattgtt gcctcctttg acggctgcat ctccaccgat 1980
ttgcgctagt agatttttaa gctgtggtgt aatcttatta actgtttcga tataatcatc 2040
gtaactgctt ctaacggcta aatttttttt atccgccatt tagaagctaa aaatattttt 2100
atttatgcag aagatttaac tagattatac aatgaactaa tatgatcctt ttccagatta 2160
tttacaaact tggtattttt tggttctgga ggaggcgaat ttaaattcgg acttggattt 2220
ggattttgtg ggttcttgat cttattatac agcgcatata ggatggcgac ggtaactgct 2280
acgcaaatac cgatcaacaa aagaatacca atcatttatt gacaataact tcactattga 2340
tcaagtatgc aatatatcat cttttcacta aataagtagt aataatgatt caacaatgtc 2400
gagatatatg gacgataata atttagttca tggaaatatc gctatgattg gtatgaatga 2460
ctccgctaac tctgtggggc gcgcagtgct ttccccacat agaataaatt agcattccga 2520
ctgtgataat aataccaagt ataaacgcca taatactcaa tactttccat gtacgagtgg 2580
gactggtaga cttactaaag tcaataaagg cgaagataca cgaaagaatc aaaagaatga 2640
ttccagcgat tagcacgccg gaaaaataat ttccaatcat aagcatcata tccatttaac 2700
taataaaaat tttaaatcgc cgaatgaaca aagtggaata taaaccatat aaaaacaata 2760
gtttgtactg caaaaataat atctattttt gttttcgaag atatggtaaa attaaatagt 2820
agtacacagc atgttataac taacagcagc aacggctcgt aattacttat catttactag 2880
acgaaaaggt ggtgggatat tttcttgctc aaataatacg aatatatcac ccatccattt 2940
tatgcgatgt ttatatactc taatctttaa tagatctata gacgacgggt ttaccaacaa 3000
tatagatttt atcgattcat ctaatttaaa cccttcctta aacgtgaatg atctattatc 3060
tggcataacg atgactctac ccgatgaatc ggacaatgta ctgggccatg tagaataaat 3120
tatcaacgaa ttatcgtcta cgaacattta tatcatttgt tttaatttta gtacgcgaat 3180
aaatagatat aaaatagaaa ataacagata ttacaaccaa tgttatggcc gcgcccaacc 3240
aggtaggcag ttttatttta tcttttacta caggttctcc tggatgtacg tcaccaacgg 3300
cggacgtagt tctagtacaa ttagacgtaa gttccgcttg ggaatttttt aacgctaaag 3360
agttaacgtt aatcgtgcac ccaacgtatt tacatctagt tctttgaaca tcttgattat 3420
aatataacca ttttctatct ctagattcgt cggtgcactc atgtaaccaa cataccctag 3480
gtcctaaata tttatctccg gaattagatt ttggataatt cgcgcaccaa caatttctat 3540
ttcctttatg atcgttacaa aagacgtata atgccgtatc cccaaaagta aaataatcag 3600
gacgaataat tctaataaac tcagaacaat atctcgcatc catatgtttg gagcaaatat 3660
cggaataagt agacatagcc ggtttccgtt ttgcacgtaa ccattctaaa caattggggt 3720
ttccaggatc gtttctacaa aatccagtca tgaaatcatc acaatgttct gtcttgtaat 3780
tattattaaa tatttttgga cagtgtttgg tatttgtctt agaacaacat tttgccacgc 3840
tatcactatc gcccaggaga taatcctttt ttataaaatg acatcgttgc ccggatgcta 3900
tataatcagt agcgtgtttt aaatccttaa tatattcagg agttacctcg ttctgataat 3960
agattaatga tccaggacga aatttgaaag aactacatgg ttctccatga attaatacat 4020
attgtttagc aaattcagga actataaaac tactacaatg atctatcgac ataccatcta 4080
tcaaacaaaa cttgggttta atttctcccg gagatgtttc ataatagtac gtataacttt 4140
cttctgcaaa cttaacagct ctattatatt caggataatt aaaacctaat tccatatatt 4200
tgtctcgtat atctgctatt cctggtgcta ttttgattct attaagagta acggctgccc 4260
ccatttttaa taatcgtcag tatttaaact gttaaatgtt ggtatatcaa catttacctt 4320
atttcccgca gtataaggtt tgttgcaggt atactgttca ggaatggtta catttatact 4380
ttttctatag tcctgtcttt cgatgttcat cacatatgca aagaacagaa taaacaaaat 4440
aatgtaagaa ataatattaa atatctgtga attcgtaaat acattgattg ccataataat 4500
tacagcagct acaatacata caatagacat tcccacagtg ttgccattac ctccacgata 4560
catttgagtt actaagcaat aggtaataac taagctagta agaggcaata gaaaagatga 4620
gataaatatc atcaatatag agattagagg agggctatat agagccaaga cgaacaaaat 4680
caaaccgagt aacgttctaa catcattatt tttgaagatt cccaaataat cattcattcc 4740
tccataatcg ttttgcatca tacctccatc tttaggcata aacgattgct gctgttcctc 4800
tgtaaataaa tctttatcaa gcactccagc acccgcagag aagtcgtcaa gcatattgta 4860
atatcttaaa taactcattt atatattaaa aaatgtcact attaaagatg gagtataatc 4920
tttatgccga actaaaaaaa atgacttgtg gtcaacccct aagtcttttt aacgaagacg 4980
gggatttcgt agaagttgaa ccgggatcat cctttaagtt tctgatacct aagggatttt 5040
acgcctctcc ttccgtaaag acgagtctag tatttgaaac attaacaacg accgataata 5100
aaattactag tatcaatcca acaaatgcgc caaagttata tcctcttcaa cgcaaagtcg 5160
tatctgaagt agtttctaat atgaggaaaa tgatcgaatc aaaacgtcct ctatacatca 5220
ctcttcactt ggcgtgtgga tttggtaaga ctattaccac gtgttatctt atggctacac 5280
acggtagaaa aaccgtcatt tgcgtaccca ataaaatgtt aatacatcaa tggaagacac 5340
aggtagaggc agtcggattg gaacataaga tatccataga tggagtaagt agtctattaa 5400
aggaactaaa gactcaaagt ccggatgtat taatagtagt cagtagacat ctgacaaacg 5460
atgccttttg taaatatatc aataagcatt atgatttgtt catcttggat gaatcacata 5520
cgtataatct gatgaacaat acagcagtta caagattttt agcgtattat cctccgatga 5580
tgtgttattt tttaactgct acacctagac catctaacag aatttattgt aacagtatta 5640
ttaatattgc caagttatcc gatctaaaaa aaactatcta tgcagtagat agtttttttg 5700
agccatattc cacagataat attagacata tgataaaacg attagatgga ccatctaata 5760
aatatcatat atataccgag aagttattat ctgtagacga gcctagaaat caacttattc 5820
ttaataccct ggtagaagaa ttcaagtcag gaactattaa tcgcatttta gttattacta 5880
aactacgtga acatatggta ttcttctaca aacgattatt agattttttc ggatcagagg 5940
ttgtatttat aggagacgcc caaaatagac gtactccaga tatggtcaaa tcaatcaagg 6000
aactaaatag atttatattc gtatccacct tattttattc cggtactggt ttagatattc 6060
ctagtttgga ttctttgttc atttgctcgg cagtaatcaa caatatgcaa atagagcaat 6120
tactagggag ggtatgtcga gaaacagaac tattagatag gacggtatat gtatttccta 6180
gcacatccat caaagaaata aagtacatga taggaaattt cgttcaacga attattagtc 6240
tgtctgtaga taaactagga tttaaacaaa aaagttatcg gaaacatcaa gaatccgatc 6300
ccacttctgt atgtacaaca tcctccagag aagaacgtgt attaaataga atatttaact 6360
cgcaaaatcg ttaagaagtt taagcgacga tccgcatgct gcgcaggcca gtgtattacc 6420
cctcatagta ttaatataat ccaatgatac ttttgtgatg tcggaaatct taaccaattt 6480
agactgacag gcagaacacg tcatgcaatc atcatcgtca tcgataactg tagtcttggg 6540
cttctttttg cggctcttca ttccggaacg cacattggtg ctatccattt aggtagtaaa 6600
aaataagtca gaatatgccc tatagcacga tcgtgcaaaa cctggtatat cgtctctatc 6660
tttatcacaa tatagtgtat cgacatcttt attattattg acctcgttta tcttggaaca 6720
tggaatggga acatttttgt tatcaacggc cacctttgcc ttaattccag atgttgtaaa 6780
attataacta aacagtctat catcgacaca aatgaaattc ttgtttagac gtttgtagtt 6840
tacgtatgcg gctcgttcgc gtctcatttt ttcagatatt gcaggtacta taatattaaa 6900
aataagaatg aaataacata ggattaaaaa taaagttatc atgacttcta gcgctgattt 6960
aactaactta aaagaattac ttagtctgta caaaagtttg aaattttcag attctgcggc 7020
tatagaaaag tataattctt tggtagaatg gggaacatct acttactgga aaataggcgt 7080
gcaaaaggta gctaatgtcg agacgtcaat atctgattat tatgatgagg taaaaaataa 7140
accgtttaat attgatccgg gctattacat tttcttaccg gtatattttg ggagcgtctt 7200
tatttattcg aagggtaaaa atatggtaga acttggatct ggaaactctt ttcaaatacc 7260
agatgatatg cgaagtgcgt gtaacaaagt attagacagc gataacggaa tagactttct 7320
gagatttgtt ttgttaaaca atagatggat aatggaagat gctatatcaa aatatcagtc 7380
tccagttaat atatttaaac tagctagtga gtacggatta aacataccca aatatttaga 7440
aattgaaata gaggaagaca cattatttga cgacgagtta tactctatta tagaacgctc 7500
tttcgatgat aaatttccaa aaatatccat atcgtatatt aagttgggag aacttaggcg 7560
gcaagttgta gactttttca aattctcatt catgtatatt gagtccatca aggtagatcg 7620
tataggagat aatattttta ttcctagcgt tataacaaaa tcaggaaaaa agatattagt 7680
aaaagatgta gaccatttaa tacgatccaa ggttagagaa catacatttg taaaagtaaa 7740
aaagaaaaac acattttcca ttttatacga ctatgatgga aacggaacag aaactagagg 7800
agaagtaata aaacgaatta tagacactat aggacgagac tattatgtta acggaaagta 7860
tttctctaag gttggtagtg caggcttaaa gcaattgact aataaattag atattaatga 7920
gtgcgcaact gtcgatgagt tagttgatga gattaataaa tccggaactg taaaacgaaa 7980
aataaaaaac caatcagcat ttgatttaag cagagaatgt ttgggatatc cagaagcgga 8040
ttttataacg ttagttaata acatgcggtt caaaatagaa aattgtaagg ttgtaaattt 8100
caatattgaa aatactaatt gtttaaataa cccgagtatt gagactatat atggaaactt 8160
taaccagttc gtctcaatct ttaatatcgt caccgatgtc aaaaaaagat tattcgagtg 8220
aaataatatg cgcctttgat ataggtgcaa aaaatcctgc cagaactgtt ttagaagtca 8280
aggataactc cgttagggta ttggatatat caaaattaga ctggagttct gattgggaaa 8340
ggcacatagc taaagatttg tcacaatatg aatacactac agttcttcta gaacgtcagc 8400
ctagaaggtc gccgtacgtc aaatttatct attttattaa aggcttttta tatcatacat 8460
cggctgccaa agttatttgc gtctcgcctg tcatgtctgg taattcatat agagatcgaa 8520
aaaagagatc ggtcgaagca tttcttgatt ggatggacac attcggattg cgagactccg 8580
ttccggatag acgcaaatta gacgatgtag cggatagttt caatttggct atgagatacg 8640
tattagataa atggaatact aattatacac cttataatag gtgtaaatct agaaattaca 8700
taaaaaaaat gtaataacgt tagtaacgcc attatggata atctatttac ctttctacat 8760
gaaatagaag atagatatgc cagaactatt tttaactttc atctaataag ttgcgatgaa 8820
ataggagata tatatggtct tatgaaagaa cgcatttcct cagaggatat gtttgataat 8880
atagtgtata ataaagatat acatcatgcc attaagaaac tagtgtattg cgacatccaa 8940
cttactaaac acattattaa tcagaatacg tatccggtat ttaacgattc ttcacaagtg 9000
aaatgttgtc attatttcga tataaactca gataatagca atattagctc tcgtacagta 9060
gagatatttg agagggaaaa gtcatctctt gtatcatata ttaaaactac caataagaag 9120
agaaaggtca attatgggga aataaagaaa actgtacatg gaggcactaa tgcaaattac 9180
ttttccggta aaaagtctga tgagtatctg agcactacag tcaggtccaa cattaatcaa 9240
ccttggatca aaaccatttc taagagaatg agagtagata tcattaatca ctctatagta 9300
acgcgtggaa aaagctctat attacaaact atagaaatta tttttactaa tagaacatgt 9360
gtgaaaatat tcaaggattc tactatgcac attattctat ccaaggacaa ggatgaaaag 9420
gggtgtatac acatgattga caaattattc tatgtctatt ataatttatt tctgttgttc 9480
gaggatatca tccaaaacga gtactttaaa gaagtagcta atgttgtaaa ccacgtactc 9540
acggctacgg cattagatga gaaattattc ctaattaaga aaatggctga acacgatgtt 9600
tatggagtta gcaatttcaa aatagggatg tttaacctga catttattaa gtcgttggat 9660
cataccgttt tcccctctct gttagatgag gatagcaaaa taaagttttt taaggggaaa 9720
aagctcaata ttgtagcatt acgatctctg gaggattgta taaattacgt gactaaatcc 9780
gagaatatga tagaaatgat gaaggaaaga tcgactattt taaatagcat agatatagaa 9840
acggaatcgg tagatcgtct aaaagaattg cttctaaaat gaaaaaaaaa cactaattca 9900
gaaatggatc aacgactcgg atataagttt ttggtgcctg atcctaaagc cggagttttt 9960
tatagaccgt tacatttcca atatgtatcg tattctaatt ttatattgca tcgattgcat 10020
gaaatcttga ccgtcaagcg gccactctta tcgtttaaga ataatacaga acgaattatg 10080
atagaaatta gcaatgttaa agtgactcct ccagattact cacctataat cgcgagtatt 10140
aaaggtaaga gttatgacgc attagccacg ttcactgtaa atatctttaa agaggtaatg 10200
accaaagagg gtatatccat cactaaaata agtagttatg agggaaaaga ttctcatttg 10260
ataaaaattc cgctactaat aggatacggg aataaaaatc cacttgatac agccaagtat 10320
cttgttccta atgtcatagg tggagtcttt atcaataaac aatctgtcga aaaagtagga 10380
attaatctag tagaaaagat tacaacatgg ccaaaattta gggttgttaa gccaaactca 10440
ttcactttct cgttttcctc cgtatcccct cctaatgtat taccgacaag atatcgccat 10500
tacaagatat ctctggatat atcacaattg gaagcgttga atatatcatc gacaaagaca 10560
tttataacgg tcaatattgt tttgctgtct caatatttat ctagagtgag tctagaattc 10620
attagacgta gtttatcata cgatatgcct ccagaagttg tctatctagt aaacgcgata 10680
atagatagtg ctaaacgaat tactgaatct attactgact ttaatattga tacatacatt 10740
aatgacctgg tggaagctga acacattaaa caaaaatctc agttaacgat caacgagttc 10800
aaatatgaaa tgctgcataa ctttttacct catatgaact atacacccga tcaactaaag 10860
ggattttata tgatatcttt actaagaaag tttctctact gtatctacca cacttctaga 10920
tatccagata gagattcgat ggtttgtcat cgcatcctaa cgtacggcaa atattttgag 10980
acgttggcac atgatgaatt agagaattac ataggcaaca tccgaaacga tatcatgaac 11040
aatcacaaga acagaggcac ttacgcggta aacattcatg tactaacaac tcctggactt 11100
aatcatgcat tttctagtct attgagtgga aagttcaaaa agtcagacgg tagttatcga 11160
acacatcctc actattcatg gatgcagaat atttctattc ctaggagtgt tggattttat 11220
ccggatcaag taaagatttc aaagatgttt tctgtcagaa aataccatcc aagtcaatat 11280
ctttactttt gttcatcgga cgttccggaa agaggtcctc aggtaggttt agtatctcaa 11340
ttgtctgtct tgagttccat tacaaatata ctaacgtctg agtatttgga tttggaaaag 11400
aaaatttgtg agtatatcag atcatattat aaagatgata taagttactt tgaaacagga 11460
tttccaatca ctatagaaaa tgctctagtc gcatctctta atccaaatat gatatgtgat 11520
tttgtaactg actttagacg tagaaaacgg atgggattct tcggtaactt ggaggtaggt 11580
attactttag ttagggatca catgaatgaa attcgcatta atattggagc gggaagatta 11640
gtcagaccat tcttggttgt ggataacgga gagctcatga tggatgtgtg tccggagtta 11700
gaaagcagat tagacgacat gacattctct gacattcaga aagagtttcc gcatgtcatc 11760
gaaatggtag atatagaaca atttactttt agtaacgtat gtgaatcggt tcaaaaattt 11820
agaatgatgt caaaggatga aagaaagcaa tacgatttat gtgactttcc tgccgaattt 11880
agagatggat atgtagcatc ttcactagtg ggaatcaatc acaattctgg acccagagct 11940
attcttggat gtgctcaagc taaacaagct atctcttgtc tgagctcgga tatacgaaat 12000
aaaatagaca atggaattca tttgatgtat ccagagaggc caatcgtgat tagtaaggct 12060
ttagaaactt caaagattgc ggctaattgc ttcggccaac atgttactat agcattaatg 12120
tcgtacaaag gtatcaatca agaggatgga attatcatca aaaaacaatt tattcagaga 12180
ggcggtctcg atattgttac agccaagaaa catcaagtag aaattccgtt ggaaaacttt 12240
aataacaaag aaagagatag gtctaacgcc tattcaaaat tagaaagtaa tggattagtt 12300
agactgaatg ctttcttgga atccggagac gctatagcac gaaatatctc atcaagaact 12360
cttgaagatg attttgctag agataatcag attagctttg atgtttccga aaaatatacc 12420
gatatgtaca aatctcgcgt tgaacgagta caagtagaac ttactgacaa agttaaggta 12480
cgagtattaa ccatgaaaga aagaagaccc attctaggag acaaatttac cactagaacg 12540
agtcaaaagg gaacagtcgc gtatatcgcg gatgaaacgg aacttccata cgatgaaaat 12600
ggtatcacac cagatgtcat tattaattct acatccatct tctctagaaa aactatatct 12660
atgttgatag aggttatttt aacagccgca tattctgcta agccgtacaa caataaggga 12720
gaaaaccgac ctgtctgttt tcctagtagt aacgaaacat ccatcgatac atatatgcaa 12780
ttcgctaaac aatgttatga gcattcaaat ccgaaattgt ctgatgaaga attatcggat 12840
aaaatctttt gtgaaaagat tctctatgat cctgaaacgg ataagcctta tgcatccaaa 12900
gtattttttg gaccaattta ttacttgcgt ctgaggcatt taactcagga caaggcaacc 12960
gttagatgta gaggtaaaaa gacgaagctc attagacagg cgaatgaggg acgaaaacgt 13020
ggaggaggta tcaagttcgg agaaatggag agagactgtt taatagcgca tggtgcagcc 13080
aatactatta cagaagtttt gaaagattcg gaagaagatt atcaagatgt gtatgtttgt 13140
gaaaattgtg gagacatagc agcacaaatc aagggtatta atacatgtct tagatgttca 13200
aaacttaatc tctctcctct cttaacaaaa attgatacca cgcacgtatc taaagtattt 13260
cttactcaaa tgaacgccag aggcgtaaaa gttaaattag atttcgaacg aaggcctcct 13320
tcgttttata aaccattaga taaagttgat ctcaaaccgt cttttctggt gtaatattct 13380
agtttggtag tagatacata tcaatatcat caaattcgag atccgaatta taaaatgggc 13440
gtggattgtt aactatagaa tcggacgtct gatattcgaa aatctgtgga gttttaggtt 13500
ttggtggagg tgtaactgct acttgggata ctgaagtctg atattcagaa agctggggga 13560
tgttctggtt cgacatccac cgatggtgtc acatcactaa tcggttcggt aacgtctgtg 13620
gacgatggag gcaccacttc tacaggttct ggttctttat cctcagtcat caacggagct 13680
acttcaatgc gaggaaatgt ataatttggt aatggtttct catgtggatc tgaagaagag 13740
gtaagatatc tactagaaag ataccgatca cgttctagtt ctcttttgta gaacttaact 13800
ttttctttct ccgcatctag ttgatattcc aacctcttca cgttcgcatg ggttacctcc 13860
gcagttttta cgagcgattt cacgttcagc cttcatgcgt cttatagcat gaattcgctt 13920
atcgttatcg ggtttagctt ctgtcacctt agcaattcct tttttattaa actctacata 13980
atcatatcca tttctattgt ttgttctaat ataaacgagt atagcatcat tgctaaattt 14040
ttcaatagta tcgaaaacag aatatcctaa accatataat atatattcag gaacactcaa 14100
actaaatgtc caggattctc ctaaatacgt aaactttaat agtgcgaaat cattcaaaaa 14160
tctaccactt atagatagat agatagtaca taaatgcgta tagtagtcta cctatctctt 14220
tattatgaaa accggcatta cgatcatata tgtcgtgata tacctgtgat ccgtttacgt 14280
taaaccataa atacatgggt gatcctataa acatgaattt atttctaatt ctcagagcta 14340
tagttaattg accgtgtaat atttgcttac atgcatactt gatacgatca ttaataagat 14400
ttttatcatt gctcgttatt tcagaatcgt atatataagg agtaccatcg tgattcttac 14460
cagatattat acaaaatact atatataaaa tatattgacc cacgttagta atcatgtaaa 14520
tgtttaacgt tttaaatttt gtattcaatg atccattatc atacgctagc atggtcttat 14580
gatattcatt ctttaaaata taatattgtg ttagccattg cattggggct cctaatggag 14640
attttttatt ctcatccatt ttaggatagg ctttcataaa gtccctaata acttcgtgaa 14700
taatgtttct atgttttcta ctgatgcatg tatttgcttc gattttttta tcccatgttt 14760
catctatcat agatttaaac gcagtaatgc tcgcaacatt aacatcttga accgttggta 14820
caattccgtt ccataaattt ataatgttcg ccatttatat aactcatttt ttgaatatac 14880
ttttaattaa caaaagagtt aagttactca tatggacgcc gtccagtctg aacatcaatc 14940
tttttagcca gagatatcat agccgctctt agagtttcag cgtgattttc caacctaaat 15000
agaacttcat cgttgcgttt acaacacttt tctatttgtt caaactttgt tgttacatta 15060
gtaatctttt tttccaaatt agttagccgt tgtttgagag tttcctcatt gtcgtcttca 15120
tcggctttaa caattgcttc gcgtttagcc tctggctttt tagcagccgt tgtagaaaaa 15180
aattcagttg ctggaattgc aagatcgtca tctccgggga aaagagttcc gtccatttaa 15240
agtacagatt ttagaaactg acactctgcg ttatttatat ttggtacaac acatggatta 15300
taaatattga tgttaataac atcagaaaat gtaaagtcta tacattgttg catcgtgtta 15360
aattttctaa tggatctagt attattgggt ccaacttctg cctgaaatcc aaatatggaa 15420
gcggatacaa aaccgtttcc tggataaacc acacatctcc acttttgctt tacatcagaa 15480
attgtgtcgt tgacatcttg aactctccta tctaatgccg gtgttccacc tatagatttt 15540
gaatattcga atgctgcatg agtagcatta aattccttaa tattgccata attttcatat 15600
attgagtaac cctggataaa aagtaaacac accgcagccg tagctaccac aataaaaaaa 15660
attgatagag agttcattta taatctatta gaagctgaca aaattttttt acacgcatca 15720
gacaatgctt taataaatag ttcaacatct acttttgtca tatcgaaccg atggtatgat 15780
tctaacctag aattacatcc gaaaaagttg actatgttca tagtcattaa gtcattaaca 15840
aacaacattc cagactctgg attataagac gatactgttt cgtcacaatt acctacctta 15900
atcatgtgat tatgaatatt ggctattaga gcaccttcta agaaatctat aatatctttg 15960
aaacacgatt taaaatcaaa ccacgaatat acttctacga agaaagttag tttacccata 16020
ggagaaataa ctataaatgg agatctaaat acaaaatccg gatctatgat agttttaaca 16080
ttattatatt ctctattaaa tacctccaca tctaaaaatg ttaattttga aactatgtct 16140
tcgtttatta ccgtacctga actaaacgct ataagctcta ttgtttgaga actctttaaa 16200
cgatattctt gaaatacatg taacaaagtt tcctttaact cggtcggttt atctaccata 16260
gttacagaat ttgtatcctt atctataata taataatcaa aatcgtataa agttatataa 16320
ttatcgcgtt cagattggga tcttttcaaa tagactaaaa accccatttc tctagtaagt 16380
atcttatgta tatgtttgta aaatatcttc atggtgggaa tatgctctac cgcagttagc 16440
cattcctcat tgacagcggt agatgtatta gacaaaacta ttccaatgtt taacaagggc 16500
cattttacga gattattaaa tccttgtttg ataaatgtag ccaatgaggg ttcgagttca 16560
acgacgattg aattctcttc ccgcggatgc tgcatgatga acgacgggat gttgttcgat 16620
tgatttggaa ttctttttcg actttttgtt tatattaaat attttaaaat ttatagcgga 16680
tagcaattca tgtaccacgg ataatgtaga cgcgtattgc gcatcgatat ctttattatt 16740
agataaattt atcaataaat gtgagaagtt tgcctcgtta aggtcttcca tttaaatatt 16800
atataaacat ttgtgtttgt atcttattcg tcttttatgg aatagttttt tactagtaaa 16860
gctgcaatta cacactttgt ccgtaaaaca taaatataaa caccagcttt tatcaatcgt 16920
tccaaaaagt cgacggcgga catttttaac atggcatcta ttttaaatac acttaggttt 16980
ttggaaaaaa catcatttta taattgtaac gattcaataa ctaaagaaaa gattaagatt 17040
aaacataagg gaatgtcatt tgtattttat aagccaaagc attctaccgt tgttaaatac 17100
ttgtctggag gaggtatata tcatgatgat ttggttgtat tggggaaggt aacaattaat 17160
gatctaaaga tgatgctatt ttacatggat ttatcatatc atggagtgac aagtagtgga 17220
acaatttaca aattgggatc gtctatcgat agactttctc taaataggac tattgttaca 17280
aaagttaata attataatta tgatacattt tttgacgatg atgattgatc gctattgcac 17340
aattttgttt ttttactttc taatatagcg tttagattct ttttcatgtg cgaatattga 17400
tttactaaaa tatctatgtt taacttttgt tctataacgt ccttatcggc ggtatcggta 17460
catatacgta attcaccttc acaaaatacg gagtcttcga taataatagc caatcgatta 17520
ttggatctag ctgtctgtat catattcaac atgtttaata tatcctttcg tttccccttt 17580
acaggcatcg atcgtagcat attttccgcg tctgagatgg aaatgttaaa actacaaaaa 17640
tgcgtaatgt tagcccgtcc taatattggt acgtgtctat aagtttggca tagtagaata 17700
atagacgtgt ttaaatgcct tccaaagttt aagaattcta ttagagtatt gcattttgat 17760
agtttatcgc ctacatcatc aaaaataagt aaaaagtgtg ctgatttttt atgattttgt 17820
gcgacagcaa tacatttttc tatgttactt ttagttcgta tcagattata ttctagagat 17880
tcctgactac taacgaaatt aatatgattt ggccaaatgt atccatcata atctggatta 17940
taaacgggtg taaacaagaa tacatgttta tattttttaa ctagtgtaga aaacagagat 18000
agtaaataga tagtttttcc agatccagat cctcccgtta aaaccattct aaacggcatt 18060
tttaataaat tttctcttga aaattgtttt tcttggaaac aattcataat tatatttaca 18120
gttactaaat taatttgata ataaatcaaa atatggaaaa ctaaggtcgt tagtagggag 18180
gagaacaaag aaggcacatc gtgacataaa taacatttat tatcatgatg acaccagaaa 18240
acgacgaaga gcagacatct gtgttctccg ctactgttta cagagacaaa attcagggaa 18300
agaataaacg caaacgcgtg attggtctat gtattagaat atctatggtt atttcactac 18360
tatctatgat taccatgtcc gcgtttctca tagtgcgcct aaatcaatgc atgtctgcta 18420
acgaggctgc tattactgac gccgctgttg ccgttgctgc tgcatcatct actcatagaa 18480
aggttgcgtc tagcactacg caatatgatc acaaagaaag ctgtaatggt ttatattacc 18540
agggttcttg ttatatatta cattcagact accagttatt ctcggatgct aaagcaaatt 18600
gcactgcgga atcatcaaca ctacccaata aatccgatgt cttgactacc tggctcattg 18660
attatgttaa ggatacatgg ggatctgatg gtaatccaat tacaaaaact acatccgatt 18720
atcaagattc tgatgtatca caagaagtta gaaagtattt ttgtgttaaa acaatgaact 18780
aatatttatt tttgtacatt aataaatgaa atcgcttaat agacaaactg taagtaggtt 18840
taagaagttg tcggtgccgg tcgctataat gatgatactc tcaaccatta ttagtggcat 18900
aggaacattt ctgcattaca aagaagaact gatgcctagt gcttgcgcca atggatggat 18960
acaatacgat aaacattgtt atttagatac taacattaaa atgtctacag ataatgcggt 19020
ttatcagtgt cgtaaattac gagccagatt gcctagaccg gatactagac atctgagagt 19080
attgtttagt attttttata aagattattg ggtaagttta aaaaagacca atgataaatg 19140
gttagatatt aataatgata aagatataga tattagtaaa ttaacaaatt ttaaacaact 19200
aaacagtacg acggatgctg aagcgtgtta tatatacaag tctggaaaac tggttaaaac 19260
agtatgtaaa agtactcaat ctgtactatg tgttaaaaaa ttctacaagt gacaacaaaa 19320
aatgaattaa taataagtcg ttaacgtacg ccgccatgga cgccgcgttt gttattactc 19380
caatgggtgt gttgactata acagatacat tgtatgatga tctcgatatc tcaatcatgg 19440
actttatagg accatacatt ataggtaaca taaaaactgt ccaaatagat gtacgggata 19500
taaaatattc cgacatgcaa aaatgctact ttagctataa gggtaaaata gttcctcagg 19560
attctaatga tttggctaga ttcaacattt atagcatttg tgccgcatac agatcaaaaa 19620
ataccatcat catagcatgc gactatgata tcatgttaga tatagaagat aaacatcagc 19680
cattttatct attcccatct attgatgttt ttaacgctac aatcatagaa gcgtataacc 19740
tgtatacagc tggagattat catctaatca tcaatccttc agataatctg aaaatgaaat 19800
tgtcgtttaa ttcttcattc tgcatatcag acggcaatgg atggatcata attgatggga 19860
aatgcaatag taatttttta tcataaaagt tgtaaagtaa ataataaaac aataaatatt 19920
gaactagtag tacgtatatt gagcaatcag aaatgatgct ggtacctctt atcacggtga 19980
ccgtagttgc gggaacaata ttagtatgtt atatattata tatttgtagg aaaaagatac 20040
gtactgtcta taatgacaat aaaattatca tgacaaaatt aaaaaagata aagagttcta 20100
attccagcaa atctagtaaa tcaactgata gcgaatcaga ctgggaggat cactgtagtg 20160
ctatggaaca aaacaatgac gtagataata tttctaggaa tgagatattg gacgatgata 20220
gcttcgctgg tagtttaata tgggataacg aatccaatgt tatggcgcct agcacagaac 20280
acatttacga tagtgttgct ggaagcacgc tgctaataaa taatgatcgt aatgaacaga 20340
ctatttatca gaacactaca gtagtactta atgaagatac caaacagaat cctaactatt 20400
catccaatcc tttcgtaaat tataataaaa ccagtatttg tagcaagtca aatccgttca 20460
ttacagaact caacaataaa tttagtgaga ataatccgtt tagacgagca catagcgatg 20520
attatcttaa taagcaagaa caagatcatg aacacgatga tatagaatca ttggtgtgat 20580
tagtttcctt tttataaaat tgaagtaata tttagtatta ttgctgccgt cacgttgtac 20640
aaatggagat attccctgta ttcggcattt ctaaaattag caattttatt gctaataatg 20700
actgtagata ttatatagat acagaacatc aaaaaattat atctgatgag atcaatagac 20760
agatggatga aacggtactt cttaccaaca tcttaagcgt agaagttgta aatgacaatg 20820
agatgtacca tcttattcct catagattat cgacgattat actctgtatt agttctgtcg 20880
gaggatgtgt tatctctata gataatgacg tcaatggcaa aaatattcta acctttccca 20940
ttgatcatgc tgtaatcata tccccactga gtaaatgtgt cgtagttagc aagggtccta 21000
caaccatatt ggttgttaaa gcggatatac ctagcaaacg attggtaaca tcgtttacaa 21060
acgacatact gtatgtaaac aatctatcac tgattaatta ttcgccgttg tctgtattca 21120
ttattagacg agttaccgac tatttggata gacacatatg cgatcagata tttgcgaata 21180
ataagtggta ttccattata accatcgaca ataagcagtt tcctattcca tcaaactgta 21240
taggtatgtc ctctgccaag tacataaatt ctagcatcga gcaagatact ttaatacatg 21300
tttgtaacct cgagcatcca ttcgacttag tatacaaaaa aatgcagtcg tacaattctg 21360
tacctatcaa ggaacaaata ttgtacggta gaattgataa tataaatatg agcattagta 21420
tttctgtgga ttaatagatt tctagtatgg ggatcattaa tcatctctaa tctctaaata 21480
cctcataaaa cgaaaaaaaa gctattatca aatactgtac ggaatggatt cattctcttc 21540
tctttttatg aaactctgtt gtatatctac tgataaaact ggaagcaaaa aatctgataa 21600
aaagaataag aataagatca aggattatta taaaataaca atagttcctg gttcctcttc 21660
cacgtctact agctcgtggt attatacaca tgcctagtaa tagtctcttt gcgttgacgg 21720
aaagcagact agaaataaca ggctaaaatg ttcagacacc ataatagttc ccaacccaga 21780
taataacaga gtaccatcaa cacattcctt taaactcaat cccaaaccca aaaccgttaa 21840
aatgtatccg gccaattgat agtagataat gaggtgtaca gcgcatgatg atttacacag 21900
taaccaaaat gaaaatactt tagtaattat aagaaatata gatggtaacg tcatcatcaa 21960
caatccaata atatgccgga gagtaaacat tgacggataa aacaaaaatg ctccgcataa 22020
ctctatcatg gcaataacac aaccaaatac ttgtaagatt cctaaattag tagaaaatac 22080
aacggatatc gatgtataag tgatctcgag aaataataag aataaagtaa tgcccgtaaa 22140
gataaacatc aacattgttt ggtaatcatt aaaccaatta gtatgaagtt gaactaattt 22200
cacagtagat tttattccag tattatcccc gcatgtataa gtacctggta agatatcttt 22260
atattccata atcaatgaga catcactatc tgataacgaa tgaagtctag cactagtatg 22320
ccatttactt aatattgtcg tcttggaagt tttattataa gttaaaatat catggttatc 22380
caatttccat ctaatatact ttgtcggatt atctatagta cacggaataa tgatggtatc 22440
attacatgct gtatactcta tggtctttgt agttgttata acaaccaacg tatagaggta 22500
tatcaacgat attctaactc ttgacatttt ttatttattt aaaatgatac ctttgttatt 22560
tattttattc tattttgcta acggtattga atggcataag tttgaaacga gtgaagaaat 22620
aatttctact tacttattag acgacgtatt atacacgggt gttaatgggg cggtatacac 22680
attttcaaat aataaactaa acaaaactgg tttaactaat aataattata taacaacatc 22740
tataaaagta gaggatgcgg aaccaataac ggaaatccca aatgttggaa aatagacggt 22800
tcagacgacc caaaacatag aggtagagga tacgctcctt atcaaaatag caaagtaacg 22860
ataatcagtc acaacggatg tgtactatct gacataaaca tatcaaaaga aggaattaaa 22920
cgatggagaa gatttgacgg accatgtggt tatgatttat acacggcgga taacgtaatt 22980
ccaaaagatg gtttacgagg agcattcgtc gataaagatg gtacttatga caaagtttac 23040
attcttttca ctgatactat cggctcaaag agaattgtca aaattccgta tatagcacaa 23100
atgtgcctaa acgacgaagg tggtccatca tcattgtcta gtcatagatg gtcgacgttt 23160
ctcaaagtcg aattagaatg tgatatcgac ggaagaagtt atagacaaat tattcattct 23220
agaactataa aaacagataa tgatacgata ctatatgtat tcttcgatag tccttattcc 23280
aagtccgcat tatgtaccta ttctatgaat accattaaac aatctttttc tacgtcaaaa 23340
ttggaaggat atacaaagca attgccgtct ccagctcctg gtatatgttt accagctgga 23400
aaagttgttc cacataccac gtttgaagtc atagaaaaat ataatgtact agatgatatt 23460
ataaagcctt tatctaacca acctatcttc gaaggaccgt ctggtgttaa atggttcgat 23520
ataaaggaga aggaaaatga acatcgggaa tatagaatat acttcataaa agaaaattct 23580
atatattcgt tcgatacaaa atctaaacaa actcgtagct cgcaagtcga tgcgcgacta 23640
ttttcagtaa tggtaacttc gaaaccgtta tttatagcag atatagggat aggagtagga 23700
atgccacaaa tgaaaaaaat acttaaaatg taatcttaat cgagtacacc gcacgacaat 23760
gaacaaacat aagacagatt atgctggtta tgcttgctgc gtaatatgcg gtctaattgt 23820
tggaattatt tttacagcga cactattaaa agttgtagaa cgtaaattag ttcatacacc 23880
atcaatagat aaaacgataa aagatgcata tattagagaa gattgtccta ctgactggat 23940
aagctataat aataaatgta tccatttatc tactgatcga aaaacctggg aggaaggacg 24000
taatgcatgc aaagctctaa atccaaattc ggatctaatt aagatagaga ctccaaacga 24060
gttaagtttt ttaagaagca ttagacgcgg atattgggta ggagaatccg aaatattaaa 24120
ccagacaacc ccatataatt ttatagctaa aaatgccacg aagaatggaa ctaaaaaacg 24180
gaaatatatt tgtagtacaa cgaatactcc caaactacat ttttatcata ccactacttc 24240
ggttagatgt tttagaaaaa aataaatatc gccgtaccgt tcttgttttt ataaaaataa 24300
caattaacaa ttatcaaatt ttttctttaa tattttacgt ggttgaccat tcttggtggt 24360
aaaataatct cttagtgttg gaatggaatg ctgtttaatg tttccgcact catcgtatat 24420
tttgacgtat gcagtcacat cgtttacgca atagtcagac tgtagttcta tcatgcttcc 24480
tacatcagaa ggaggaacag ttttaaagtc tcttggtttt aatctattgc cattagtttt 24540
catgaaatcc tttgttttat ccacttcaca ttttaaataa atgtccacta tacattcttc 24600
tgttaatttt actagatcgt catgggtcat agaatttata ggttccgtag tccatggatc 24660
caaactagca aacttcgcgt atacggtatc gcgattagtg tatacaccaa ctgtatgaaa 24720
attaagaaaa cagtttaata aatcaacaga aatatttaat cctccgtttg atacagatgc 24780
gccatattta tggatttcgg attcacacgt tgtttgtctg aggtgttcgt ctagtgttgc 24840
ttctacgtaa acttcgattc ccatatattc tttattgtca gaatcgcata ccgatttatc 24900
atcatacact gtttgaaaac taaatggtat acacatcaaa ataataaata ataacgagta 24960
cattctgcaa tattgttatc gtaattggaa aaatagtgtt cgagtgagtt ggattatgtg 25020
agtattggat tgtatatttt attttatatt ttatattttg tagtaagaat agaatgctaa 25080
tgtcaagttt attccaatag atgtcttatt aaaaaacata tataataaat aacaatggct 25140
gaatggcata aaattatcga ggatatctca aaaaataata agttcgagga tgccgccatc 25200
gttgattaca agactacaaa gaatgttcta gctgctattc ctaacagaac atttgccaag 25260
attaatcctc tcatcactaa tcgtaatatt ctaaaacctc ttattggtca gaaatattgt 25320
attgtatata ctaactctct aatggatgag aacacgtatg ctatggagtt gcttactggg 25380
tacgcccctg tatctccgat cgttatagcg agaactcata ccgcacttat atttttgatg 25440
ggtaagccaa caacatccag acgtgacgtg tatagaacgt gtagagatca cgctacccgt 25500
gtacgtgcaa ctggtaatta aaataaaaag taatattcat atgtagtgtc aattttaaat 25560
gatgatgatg aaatggataa tatccatatt gacgatgtca ataatgccgg tattggcata 25620
cagttcatcg atttttagat ttcattcaga ggatgtggaa ttatgttatg ggcatttgta 25680
ttttgatagg atctataatg tagtaaatat aaaatataat ccgcatattc catatagata 25740
taattttatt aatcgcacgt taaccgtaga tgaactagac gataatgtct tttttacaca 25800
tggttatttt ttaaaacaca aatatggttc acttaatcct agtttgattg tctcattatc 25860
aggaaactta aaatataatg atatacaatg ctcagtaaat gtatcgtgtc tcattaaaaa 25920
tttggcaacg agtacatcta ctatattaac atctaaacat aagacttatt ctctacatcg 25980
gtccacgtgt attactataa taggatacga ttctattata tggtataaag atataaatga 26040
catctatgat tttactgcaa tatgtatgct aatagcgtct acattgatag tgaccatata 26100
cgtgtttaaa aaaataaaaa tgaactctta attatgctat gctattagaa atggataaaa 26160
tcaaaattac ggttgattca aaaattggta atgttgttac catatcgtat aacttggaaa 26220
agataactat tgatgtcaca cctaaaaaga aaaaagaaaa ggatgtatta ttagcgcaat 26280
cagttgctgt cgaagaggca aaagatgtca aggtagaaga aaaaaatatt atcgatattg 26340
aagatgacga tgatatggat gtagaaagcg cataatacga tctataaaaa taagtatata 26400
aatacttttt atttactgta ctcttactgt gtagtggtga taccctactc gattattttt 26460
ttaaaaaaaa atacttattc tgattcttct agccatttcc gtgttcgttc gaatgccaca 26520
tcgacgttaa agatagggga gtagttgaaa tctagttctg cattgttggt acgcacctca 26580
aatgtagtgt tggatatctt caacgtatag ttgttgagta gtgatggttt tctaaataga 26640
attctcttca tatcattctt gcacgcgtac atttttagca tccatcttgg aatcctagat 26700
ccttgttcta ttcccaatgg tttcatcaat agaagattaa acatatcgta cgaacacgat 26760
ggagagtaat cgtagcaaaa gtaagcattt cctttaatct cagatcccgg atactggata 26820
tattttgcag ccaacacgtg catccatgca gcatttccta catatacccg gctatgtacc 26880
gcgttatcat cgactgtacg atacataatg ttaccgtgtt gcttacattg ctcgtaaaag 26940
actttcatca atttgtctcc ttctccgtaa attccagtgg gtcttaggca acaagtatac 27000
aattttgctc cattcatgat tacggaatta ttggctttca taaccagttg ctcggccata 27060
cgtttacttt ttgcgtatac atgtcctggt gatatatcat aaagggtatg ctcatggccg 27120
atgaatggat caccgtgttt attgggtcct attgcttcca tgctactagt atagatcaaa 27180
tacttgattc ctaggtccac acaagctgcc aatatagtct gtgttccata atagtttact 27240
ttcatgattt cattatcggt gtattttcca aatacatcca ctagagcagc tgtatgaata 27300
atcagattta ccccatctag cgcttctctt accttatcaa agtcgtttat atcacattgt 27360
atatagttta taaccttaac tttcgaggtt attggttgtg gatcttctac aatatctatg 27420
actctgattt cttgaacatc atctgcacta attaacagtt ttactatata cctgcctaga 27480
aatccggcac caccagtaac cgcgtacacg gccattgctg ccactcataa tatcagacta 27540
cttattctat tttactaaat aatggctgtt tgtataatag accacgataa tatcagagga 27600
gttatttact ttgaaccagt ccatggaaaa gataaagtta ttggattaaa atccggaacg 27660
tatagtttga taattcatcg ttacggagat attagtcaag gatgtgattc cataggcagt 27720
ccagaaatat ttatcggtaa catctttgta aacagatatg gtgtagcata tgtttattta 27780
gatacagatg taaatatatc tacaattatt ggaaaggcgt tatctatttc aaaaaatgat 27840
cagagattag cgtgtggagt tattggtatt tcttacataa atgaaaagat aatacatttt 27900
cttacaatta acgagaatgg cgtttgatat atcagttaat gcgtctaaaa caataaatgc 27960
attagtttac ttttctactc agcaaaataa attagtcata cgtaatgaag ttaatgatac 28020
acactacact gtcgaatttg atagggacaa agtagttgac acgtttattt catataatag 28080
acataatgac tccatagaga taagaggggt gcttccagag gaaactaata ttggttgcgc 28140
ggttaatacg ccggttagta tgacttactt gtataataag tatagtttta aactgatttt 28200
agcagaatat ataagacaca gaaatactat atccggcaat atttattcgg cattgatgac 28260
actagatgat ttggctatta aacagtatgg agacattgat ctattattta atgagaaact 28320
taaagtagac tccgattcgg gactatttga ctttgtcaac tttgtaaagg atatgatatg 28380
ttgtgattct agaatagtag tagctctatc tagtctagta tctaaacatt gggaattgac 28440
aaataaaaaa tataggtgta tggcattagc cgaacatata tctgatagta ttccaatatc 28500
tgagctatct agactacgat acaatctatg taagtatcta cgcgggcaca ctgagagcat 28560
agaggatgaa tttgattatt ttgaagacga tgattcgtct acatgttctg ccgtaaccga 28620
cagggaaacg gatgtataat tttttttata gcgtgaagga tatgataaaa aatataattg 28680
ttgtatttat cccattccaa tcaccttata tgattctgta acacaatgaa ggagtcttat 28740
agatgtatag aggtcagata ctggtttgat aaactgttta ttccacataa gtatgtttga 28800
ctttatggtt agacccgcat actttaacaa atcactgaaa attggagtta ggtattgacc 28860
tctcagaatc agttgccgtt ctggaacatt aaatgtattt tttatgatat actccaacgc 28920
atttatgtgg gcatacaaca agtcattact aatggagtat tccaagagaa gagatttcaa 28980
cagactgttt atgaactcga atgccgcctc attgtcgctt atattgatga tgtcgaattc 29040
tcccaatatc atcaccgatg agtagctcat cttgttatcg ggatccaagt tttctaaaga 29100
tgtcattaaa ccctcgatca tgaatggatt tatcatcatc gtttttatgt tggacatgag 29160
cttagtccgt ttgtccacat ctatagacga cgatttctga attatttcat atatccctct 29220
ctttaactcc aggaacttgt caggatggtc tactttaata tgttctcgtc taagagatga 29280
aaatctttgg atggttgcac gcgacttttc tctaaaggat cctctcttaa atgaatccat 29340
cttatccttg gacaagatgg acagtctatt ttccttagat ggtttaatat ttttgttacc 29400
catgatctat aaaggtagac ctaatcgtct cggatgacca tatatttatt ttcagtttta 29460
ttatacgcat aaattgtaaa aaatatgtta ggtttacaaa aatgtctcgt ggggcattaa 29520
tcgtttttga aggattggac aaatctggaa aaacaacaca atgtatgaac atcatggaat 29580
ctataccggc aaacacgata aaatatctta actttcctca gagatccact gtcactggaa 29640
agatgataga tgactatcta actcgtaaaa aaacctataa tgatcatata gttaatctat 29700
tattttgtgc aaatagatgg gagtttgcat cttttataca agaacaacta gaacagggaa 29760
ttactttaat agttgataga tacgcattct ctggagtagc gtatgccgcc gctaaaggcg 29820
cgtcaatgac tctcagtaag agttatgaat ctggattgcc taaacccgac ttagttatat 29880
tcttggaatc tggtagcaaa gaaattaata gaaacgtcgg cgaggaaatt tatgaagatg 29940
ttacattcca acaaaaggta ttacaagaat ataaaaaaat gattgaagaa ggagatattc 30000
attggcaaat tatttcttct gaattcgagg aagatgtaaa gaaggagttg attaagaata 30060
tagttataga ggctatacac acggttactg gaccagtggg gcaactgtgg atgtaatagt 30120
gaaattacat tttttataaa tggatgaagc atattactct ggcaacttgg aatcagtact 30180
cggatacgtg tccgatatgc ataccgaact cgcatcaata tctcaattag ttattgccaa 30240
gatagaaact atagataatg atatattaaa caaggacatt gtaaatttta tcatgtgtag 30300
atcaaacttg gataatccat ttatctcttt cctagatact gtatatacta ttatagatca 30360
agagatctat cagaccgaat tgattaattc attagacgac aatgaaatta tcgattgtat 30420
agttaacaag tttatgagct tttataagga taacctagaa aatatagtag atgctatcat 30480
tactctaaaa tatataatga ataatccaga ttttaaaact acgtatgccg aagtactcgg 30540
ttccagaata gcggatatag atattaaaca agtgatacgt gagaatatac tacaattgtc 30600
taataatatc cgcgaacgat atttgtgaaa atattaaaaa aaaatacttt ttttattaaa 30660
tgacgtcgct tcgcgaattt agaaaattat gctgtgatat atatcacgca tcaggatata 30720
aagaaaaatc taaattaatt agagacttta taacagatag ggatgataaa tatttgatca 30780
ttaagctatt gcttcccgga ttagacgata gaatttataa catgaacgat aaacaaatta 30840
taaaattata tagtataata tttaaacaat ctcaggaaga tatgctacaa gatttaggat 30900
acggatatat aggagacact attaggactt tcttcaaaga gaacacagaa atccgtccac 30960
gagataaaag cattttaact ttagaagaag tggatagttt tttaactacg ttatcatccg 31020
taactaaaga atcgcatcaa ataaaattat tgactgatat cgcatccgtt tgtacatgta 31080
atgatttaaa atgtgtagtc atgcttattg ataaagatct aaaaattaaa gcgggccctc 31140
ggtacgtact taacgctatt agtcctcatg cctatgatgt gtttagaaaa tctaataact 31200
tgaaagagat aatagaaaat gcatctaaac aaaatctaga ctctatatct atttctgtta 31260
tgactccaat taatcccatg ttagcggaat cgtgtgattc tgtcaataag gcgtttaaaa 31320
aatttccatc aggaatgttt gcggaagtca aatacgatgg tgaaagagta caagttcata 31380
aaaataataa cgagtttgcc ttctttagta gaaacatgaa accagtactc tctcataaag 31440
tggattatct caaagaatac ataccgaaag catttaaaaa agctacgtct atcgtattgg 31500
attctgaaat tgttcttgta gacgaacata atgtaccgct cccgtttgga agtttaggta 31560
tacacaaaaa gaaagaatat aaaaactcta acatgtgttt gttcgtgttt gactgtttgt 31620
actttgatgg attcgatatg acggacattc cattgtacga acgaagatct tttctcaaag 31680
atgttatggt tgaaataccc aatagaatag tattctcaga gttgacgaat attagtaacg 31740
agtctcagtt aactgacgta ttggatgatg cactaacgag aaaattagaa ggattggtct 31800
taaaagatat taatggagta tacgaaccgg gaaagagaag atggttaaaa ataaagcgag 31860
actatttgaa cgagggttcc atggcagatt ctgccgattt agtagtacta ggtgcttact 31920
atggtaaagg agcaaagggt ggtatcatgg cagtctttct aatgggttgt tacgacgatg 31980
aatccggtaa atggaagacg gttaccaagt gttcaggaca cgatgataat acgttaaggg 32040
agttgcaaga ccaattaaag atgattaaaa ttaacaagga tcccaaaaaa attccagagt 32100
ggttagtagt taataaaatc tatattcccg attttgtagt agaggatcca aaacaatctc 32160
agatatggga aatttcagga gcagagttta catcttccaa gtcccatacc gcaaatggaa 32220
tatccattag atttcctaga tttactagga taagagagga taaaacgtgg aaagaatcta 32280
ctcatctaaa cgatttagta aacttgacta aatcttaata gttacataca aattaaaata 32340
acactattta gttggtggtc gccatggatg gtgttattgt atactgtcta aacgcgttag 32400
taaaacatgg cgaggaaata aatcatataa aaaatgattt catgattaaa ccatgttgtg 32460
aaaaagtcaa gaacgttcac attggcggac aatctaaaaa caatacagtg attgcagatt 32520
tgccatatat ggataatgcg gtatccgatg tatgcaattc actgtataaa aagaatgtat 32580
caagaatatc cagatttgct aatttgataa agatagatga cgatgacaag actcctactg 32640
gtgtatataa ttattttaaa cctaaagatg ccattcctgt tattatatcc ataggaaagg 32700
atagagatgt ttgtgaacta ttaatctcat ctgataaagc gtgtgcgtgt atagagttaa 32760
attcatataa agtagccatt cttcccatgg atgtttcctt ttttaccaaa ggaaatgcat 32820
cattgattat tctcctgttt gatttctcta tcgatgcggc acctctctta agaagtgtaa 32880
ccgataataa tgttattata tctagacacc agcgtctaca tgacgagctt ccgagttcca 32940
attggttcaa gttttacata agtataaagt ccgactattg ttctatatta tatatggttg 33000
ttgatggatc tgtgatgcat gcaatagctg ataatagaac ttacgcaaat attagcaaaa 33060
atatattaga caatactaca attaacgatg agtgtagatg ctgttatttt gaaccacaga 33120
ttaggattct tgatagagat gagatgctca atggatcatc gtgtgatatg aacagacatt 33180
gtattatgat gaatttacct gatgtaggcg aatttggatc tagtatgttg gggaaatatg 33240
aacctgacat gattaagatt gctctttcgg tggctggtat ttggaaagtt ttataggtag 33300
ttgatagaac aaaatacata attttgtaaa aataaatcac tttttatact aatatgacac 33360
gattaccaat acttttgtta ctaatatcat tagtatacgc tacacctttt cctcagacat 33420
ctaaaaaaat aggtgatgat gcaactttat catgtaatcg aaataataca aatgactacg 33480
ttgttatgag tgcttggtat aaggagccca attccattat tcttttagct gctaaaagcg 33540
acgtcttgta ttttgataat tataccaagg ataaaatatc ttacgactct ccatacgatg 33600
atctagttac aactatcaca attaaatcat tgactgctag agatgccggt acttatgtat 33660
gtgcattctt tatgacatcg cctacaaatg acactgataa agtagattat gaagaatact 33720
ccacagagtt gattgtaaat acagatagtg aatcgactat agacataata ctatctggat 33780
ctacacattc accggaaact agttctgaga aacctgatta tatagataat tctaattgct 33840
cgtcggtatt cgaaatcgcg actccggaac caattactga taatgtagaa gatcatacag 33900
acaccgtcac atacactagt gatagcatta atacagtaag tgcatcatct ggagaatcca 33960
caacagacga gactccggaa ccaattactg ataaagaaga agatcataca gttacagaca 34020
ctgtctcata cactacagta agtacatcat ctggaattgt cactactaaa tcaaccaccg 34080
atgatgcgga tctttatgat acgtacaatg ataatgatac agtaccatca actactgtag 34140
gcggtagtac aacctctatt agcaattata aaaccaagga ctttgtagaa atatttggta 34200
ttaccgcatt aattatattg tcggccgtgg caatattctg tattacatat tatatatata 34260
ataaacgttc acgtaaatac aaaacagaga acaaagtcta gatttttgac ttacataaat 34320
gtctgggata gtaaaatcta tcatattgag cgggccatct ggtttaggaa agacagccat 34380
agccaaaaga ctatgggaat atatttggat ttgtggtgtc ccataccact agatttcctc 34440
gtcctatgga acgagaaggt gtcgattacc attacgttaa cagagaggcc atctggaagg 34500
gaatagccgc cggaacatac tgagttttta ggaaatattt acggaacttc taaaactgct 34560
gtgaatacag cggctattaa taatcgtatt tgtgtgatgg atctaaacat cgacggtgtt 34620
agaagtttta aaaatactta cctaatgcct tactcggtgt atataagacc tacctctctt 34680
aaaatggttg agaccaagct tcgttgtaga aacactgaag cggatgatga gattcatcgt 34740
cgtgtgatgt tggcaaaaac tgacatggat gaggcaggtg aagccggtct attcgacact 34800
attatcattg aagatgatgt gaatttagca tatagtaagt taattcagat actacaggac 34860
cgtattagaa tgtattttaa cactaattag agacttaaga cttaaaactt gataattaat 34920
aatataactc gtttttatat gtggctattt caacgtctaa tgtattagtt aaatattaaa 34980
acttaccacg taaaacttaa aatttaaaat gatatttcat tgacagatag atcacacatt 35040
atgaactttc aaggacttgt gttaactgac aattgcaaaa atcaatgggt cgttggacca 35100
ttaataggaa aaggtggatt tggtagtatt tatactacta atgacaataa ttatgtagta 35160
aaaatagagc ccaaagctaa cggatcatta tttaccgaac aggcatttta tactagagta 35220
cttaaaccat ccgttatcga agaatggaaa aaatctcaca atataaagca cgtaggtctt 35280
atcacgtgca aggcatttgg tctatacaaa tccattaatg tggaatatcg attcttggta 35340
attaatagat taggtgcaga tctagatgcg gtgatcagag ccaataataa tagattacca 35400
aaaaggtcgg tgatgttgat cggaatcgaa atcttaaata ccatacaatt tatgcacgag 35460
caaggatatt ctcacggaga tattaaagcg agtaatatag tcttggatca aatagataag 35520
aataaattat atctagtgga ttacggattg gtttctaaat tcatgtctaa tggcgaacat 35580
gttccattta taagaaatcc aaataaaatg gataacggta ctctagaatt tacacctata 35640
gattcgcata aaggatacgt tgtatctaga cgtggagatc tagaaacact tggatattgt 35700
atgattagat ggttgggagg tatcttgcca tggactaaga tatctgaaac aaagaattgt 35760
gcattagtaa gtgccacaaa acagaaatat gttaacaata ctgcgacttt gttaatgacc 35820
agtttgcaat atgcacctag agaattgctg caatatatta ccatggtaaa ctctttgaca 35880
tattttgagg aacccaatta cgacaagttt cggcacatat taatgcaggg tgtatattat 35940
taagtgtggt gtttggttga tgtaaaattt ttgtcgataa aaattaaaaa ataacttaat 36000
ttattattga tctcgtgtgt acaaccgaaa tcatggcgat gttttacgca cacgctctcg 36060
gtgggtacga cgagaatctt catgcctttc ctggaatatc atcgactgtt gccaatgatg 36120
tcagtttata ataacaagta tgacattgta aaagacaaat atatgtggtg ttacagtcag 36180
gtgaacaaga gatatattgg agcactgctg cctatgtttg agtgcaatga atatctacaa 36240
attggagatc cgatccatga tcaagaagga aatcacatat cgccacaaaa actactatgc 36300
tctaagcgga atcgggtacg agagtctaga cttgtgtttg gaaggagtag ggattcatca 36360
tcacgtactt gaaacagaaa acgctgtata tggaaaagtt caacatgatt attctactat 36420
caaagagaag gccaaagaaa tgaatgcact cagttcagga cctatcatcg attaccacgt 36480
ctggatagga gattgtatct gtcaagttac tgctgtggac gtacatggaa aggaaattat 36540
gagaatgaga ttcaaaaagg gtgcggtgct tccgatccca aatctggtaa aagttaaact 36600
tggggagaat gatacagaaa atctttcttc tactatatcg gcggcaccat cgaggtaacc 36660
acctctctgg aagacagtgt gaatcatgta ctcatgaaac gtttggaatc tatacgccat 36720
atgtggtctg ttgtatatga tcattttgat attgtgaatg gtaaagaatg ctgttatgtg 36780
catacgcatt tgtctaatca aaatcttata ccgagtactg taaaaacaaa tttgtacatg 36840
aagactatgg gatcatgcat tcaaatgagt atcttagcga actgaaggaa tcaggtggat 36900
ggagtcccag accagaaatg caggaatttg aatatccaga tggagtggaa gacactgaat 36960
caattgagag attggtagag gagttcttca atagatcaga acttcaggct ggtaaatcta 37020
ttaatgttaa acatacatct gtttcagcta agcaactaag aacacgtata ctctcatctt 37080
ttgccaacac agagggtgga tatttgttca ttggagttga taataataca cacaaagtat 37140
ttggattcac ggtgggttac gactacctca gactgataga gaatgatata gaaaagcata 37200
tcaaaagact ttgtgttgtg tatttctgtg agaagaaaga ggacatcaag tacacgtgtc 37260
gattcatcaa ggtatataaa cctggggatg aggctacctc gacatacgtg tgcgctatca 37320
aagtggaaag atgctgttgt gctgtgtttg cagattggcc agaatcatgg tatcaagaag 37380
tattctccag atgaataggt gtcacatata aaattttaat taatgtaact atagagaaca 37440
aataataggt tgtaatatca tatagacaat aactaacaat taattagtaa ctgttatctc 37500
tttttaacta actaactata cctattaata catcgtaatt atagttctta acatctatta 37560
atcattgatt cgcttcttta attttttata aaccaacatt gttaattgaa aagggataac 37620
atgttacaga atataaatta tatatggatt ttttttaaaa aggaaatact tgactggagt 37680
gtatatttat ctcttcatta tatagcacgc gtgttttcca atttttccac atcccatata 37740
atacaggatt ataatctcgt tcgaacatac gagaaagtgg ataaaacaat agttgatttt 37800
ttatctaggt tgccaaattt attccatatt ttagaatatg gggaaaatat tctacatatt 37860
tattctatgg atgatgctaa tacgaatatt ataatttttt ttctagatag agtattaaat 37920
attaataaga acgggtcatt tatacacaat ctcaggttat catcatccat taatataaaa 37980
gaatatgtat atcaattagt taataatgat catccagata ataggataag actaatgctt 38040
gaaaatggac gtagaacaag acattttttg tcctatatat cagatacagt taatatctat 38100
atatgtattt tatatagatg ccgaagacag ttacggttgt acattattac atagatgtat 38160
atatcactat aagaaatcag aatcagaatc agaatcatac aatgaattaa ttaagatatt 38220
gttaaataat ggatcagatg tagataaaaa agatacgtac ggaaacacac cttttatcct 38280
attatgtaaa cacgatatca acaacgtgga attgtttgag atatgtttag agaatgctaa 38340
tatagactct gtagacttta atagatatac acctcttcat tatgtctcat gtcgtaataa 38400
atatgatttt gtaaagttat taatttctaa aggagcaaat gttaatgcgc gtaataaatt 38460
cggaactact ccattttatt gtggaattat acacggtatc tcgcttataa aactatattt 38520
ggaatcagac acagagttag aaatagataa tgaacatata gttcgtcatt taataatttt 38580
tgatgctgtt gaatctttag attatctatt atccagagga gttattgata ttaactatcg 38640
tactatttac gacgctgtca gttataatgc gtataatacg ttggtctatc tattaaacag 38700
aaatggtgat tttgagacga ttactactag tggatgtaca tgtatttcgg aagcagtcgc 38760
aaacaacaac aaaataataa tggaagtact attgtctaaa cgaccatctt tgaaaattat 38820
gatacagtct atgatagcaa ttactaaaca taaacagcat aatgcagatt tattgaaaat 38880
gtgtataaaa tatactgcgt gtatgaccga ttatgatact cttatagatg tacaatcact 38940
acagcaatat aaatggtata ttttaagatg tttcgatgaa atagatatca tgaagagatg 39000
ttatataaaa aataaaactg tattccaatt agttttttgt atcaaagaca ttaatacttt 39060
aatgagatac ggtaaacatc cttctttcgt gaagtgcact agtctcgacg tatacggaag 39120
tcgtgtacgt aatatcatag catctattag atatcgtcag agattaatta gtctattatc 39180
caagaagctg gatcctggag ataaatggtc gtgttttcct aacgaaataa aatataacga 39240
taacgaactg tccacatatc taaaaatctt ataaacacta ttaaaatata aaatcacact 39300
acatcattgt ttccttttag tgctcgacag tgtatactat ttttaacgct cataaataaa 39360
aatgaaaacg atttccgttg ttacgttgtt atgcgtacta cctgctgttg tttattcaac 39420
atgtactgta cccactatga ataacgctaa attaacgtct accgaaacat cgtttaataa 39480
taaccagaaa gttacgttta catgtgatca gggatatcat tcttcggatc caaatgctgt 39540
ctgcgaaaca gataaatgga aatacgaaaa tccatgcaaa aaaatgtgca cagtttctga 39600
ttacatctct gaactatata ataaaccgct atacgaagtg aattccacca tgacactaag 39660
ttgcaacggc gaaacaaaat attttcgttg cgaagaaaaa aatggaaata cttcttggaa 39720
tgatactgtt acgtgtccta atgcggaatg tcaacctctt caattagaac acggatcgtg 39780
tcaaccagtt aaagaaaaat actcatttgg ggaatatata actatcaact gtgatgttgg 39840
atatgaggtt attggtgctt cgtacataag ttgtacagct aattcttgga atgttattcc 39900
atcatgtcaa caaaaatgtg atataccgtc tctatctaat ggattaattt ccggatctac 39960
attttctatc ggtggcgtta tacatcttag ttgtaaaagt ggttttatac taacgggatc 40020
tccatcatcc acatgtatcg acggtaaatg gaatcccata ctcccaacat gtgtacgatc 40080
taacgaaaaa tttgatccag tggatgatgg tcccgacgat gagacagatt tgagcaaact 40140
ctcgaaagac gttgtacaat atgaacaaga aatagaatcg ttagaagcaa cttatcatat 40200
aatcatagtg gcgttaacaa ttatgggcgt catattttta atctccgtta tagtattagt 40260
ttgttcctgt gacaaaaata atgaccaata taagttccat aaattgctac cgtgaatata 40320
aatccgttaa aataatgaat aattaataat taataattta ataacaaaca agtatcaaaa 40380
gattaaagac ttatagctag aatcaattga gatgtcttct tcagtggatg ttgatatcta 40440
cgatgccgtt agagcatttt tactcaggca ctattataac aagagattta ttgtgtatgg 40500
aagaagtaac gccatattac ataatatata caggctattt acaagatgcg ccgttatacc 40560
gttcgatgat atagtacgta ctatgccaaa tgaatcacgt gttaaacaat gggtgatgga 40620
tacacttaat ggtataatga tgaatgaacg cgatgtttct gtaagcgttg gcaccggaat 40680
actattcatg gaaatgtttt tcgattacaa taaaaatagt atcaacaatc aactaatgta 40740
tgatataatt aatagcgtat ctataattct agctaatgag agatatagaa gcgcttttaa 40800
cgacgatggt atatacatcc gtagaaatat gattaacaag ttgtacggat acgcatctct 40860
aactactatt ggcacgatcg ctggaggtgt ttgttattat ctgttgatgc atctagttag 40920
tttgtataaa taattatttc aatatactag ttaaaatttt aagattttaa atgtataaaa 40980
aactaataac gtttttattt gtaataggtg cattagcatc ctattcgaat aatgagtaca 41040
ctccgtttaa taaactgagt gtaaaactct atatagatgg agtagataat atagaaaatt 41100
catatactga tgataataat gaattggtgt taaattttaa agagtacaca atttctatta 41160
ttacagagtc atgcgacgtc ggatttgatt ccatagatat agatgttata aacgactata 41220
aaattattga tatgtctact attcaacgca gaggtcacac gtgtagaata tctaccaaat 41280
tatcatgcca ttatgataag tacccttata ttcacaaata tgatggtgat gagcgacaat 41340
attctattac tgcagaggga aaatgctata aaggaataaa atatgaaata agtatgatca 41400
acgatgatac tctattgaga aaacatactc ttaaaattgg atctacttat atatttgatc 41460
gtcatggaca tagtaataca tattattcaa aatatgattt ttaaaaattt aaaatatatt 41520
atcacttcag tgacagtagt caaataacaa acaacaccat gagatatatt ataattctcg 41580
cagttttgtt cattaatagt atacacgcta aaataactag ttataagttt gaatccgtca 41640
attttgattc caaaattgaa tggactgggg atggtctata caatatatcc cttaaaaatt 41700
atggcatcaa gacgtggcaa acaatgtata caaatgtacc agaaggaaca tacgacatat 41760
ccgcatttcc aaagaatgat ttcgtatctt tctgggttaa atttgaacaa ggcgattata 41820
aagtggaaga gtattgtacg ggaccaccga ctgtaacatt aactgaatac gacgaccatc 41880
cgtatgctac tagaggtagc aaaaagattc ctatttacaa acgcggtgac atgtgtgata 41940
tctacttgtt gtatacggct aacttcacat tcggagattc taaagaacca gtaccatatg 42000
atatcgatga ctacgattgc acgtctacag gttgcagcat agactttgtc acaacagaaa 42060
aagtgtgcgt gacagcacag ggagccacag aagggtttct cgaaaaaatt actccatgga 42120
gttcgaaagt atgtctgaca cctaaaaaga gtgtatatac atgcgcaatt agatccaaag 42180
aagatgttcc caatttcaag gacaaaatgg ccagagttat caagagaaaa tttaactaaa 42240
tttctcggta gcacatcaaa tgatgttacc acttttctta gcatgcttaa cttgactaaa 42300
tattcataac taatttttat taatgataca aaaacgaaat aaaactgcat attatacact 42360
ggttaacgcc cttataggct ctaaccattt tcaagatgag gtccctgatt atagtccttc 42420
tgttcccctc tatcatctac tccatgtcta ttagacgatg tgagaagact gaagaggaaa 42480
catggggatt gaaaataggg ttgtgtataa ttgccaaaga tttctatccc gaaagaactg 42540
attgcagtgt tcatctccca actgcaagtg aaggcaatgg attcagggat atacgaaaca 42600
ccgataaatt ataaaaaaag caatgtgtcc gctgtttccg ttaataatac tattttcgta 42660
actggcggat tattcataaa taactctaat agcacgatcg tggttaacaa tatggaaaaa 42720
cttgacattt ataaagacaa acaatggtcg attatagaaa tgcctatggc tagggtatat 42780
cacggcatcg actcgacatt tggaatgtta tattttgccg gaggtctatc cgttaccgaa 42840
caatatggta atttagagaa aaacaacgag atatcttgtt acaatcctag aacgaataag 42900
tggtttgata tttcatatac tatttataag atatccatat catcattgtg taaactaaat 42960
aacgtcttct atgtatttag taaggacatt ggatatgtgg aaaagtatga tggtctcccc 43020
gctataaagg cattatcaac ttctccttat tgattgaaaa tgaaaatata aatagttttt 43080
atgtatagca gtattaccct atagttttat tgcttactac taacatggat acagatacag 43140
atgttacaaa tgtagaagat atcatgaatg aaatagatag agagaaagaa gaaatactaa 43200
aaaatgtaga aattgaaaat aataaaaaca ttaacaagaa tcatcccaat gaatatatta 43260
gagaagcact cgttattaat acaagtagta atagtgattc cattgataaa gaagttatag 43320
aatgtatcag tcacgatgta ggaatataga tcatatctac taatttttat aatcaataca 43380
aaacataaaa aacaactcgt tattacatag caggcatgga atccttcaag tattgttttg 43440
ataacgatgg caagaaatgg attatcggaa atactttata ttctggtaat tcaatactct 43500
ataaggtcag aaaaaatttc actagttcgt tctacaatta cgtaatgaag atagatcaca 43560
aatcacacaa gccattgttg tctgaaatac gattctatat atctgtattg gatcctttga 43620
ctatcgacaa ctggacacgg gaacgtggta taaagtattt ggctattcca gatctgtatg 43680
gaattggaga aaccgatgat tatatgttct tcgttataaa gaatttggga agagtattcg 43740
ccccaaagga tactgaatca gtcttcgaag catgcgtcac tatgataaac acgttagagt 43800
ttatacactc tcgaggattt acccatggaa aaatagaacc gaggaatata ctgattagaa 43860
ataaacgtct ttcactaatt gactattcta gaactaacaa actatacaag agtggaaact 43920
cacatataga ttacaacgag gacatgataa cttcaggaaa tatcaattat atgtgtgtag 43980
acaatcatct tggagcaaca gtttcaaaac gaggagattt agaaatgttg ggatattgca 44040
tgatagaatg gttcggtggc aaacttccat ggaaaaacga aagtagtata aaagtaataa 44100
aacaaaaaaa agaatataaa aaatttatag ctactttctt tgaggactgt tttcctgaag 44160
gaaatgaacc tctggaatta gttagatata tagaattagt atacacgtta gattattctc 44220
aaactcctaa ttatgacaga ctacgtagac tgtttataca agattgaaat attctttttt 44280
tatagagtgt ggtagtgtta cggatatcta atattaatat tagactatct ctatcgcgct 44340
acacgaccaa tatcgattac tatggatatc ttctatgaaa ggagagaatg tattcatttc 44400
tccagcgtca atctcgtcag tattgacaat actgtattat ggagctaatg gatccactgc 44460
tgaacagcta tcaaaatatg tagaaaagga ggagaacacg gataaggtta gcgctcagaa 44520
tatctcattc aaatccatga ataaagtata tgggcgatat tctgccgtgt ttaaagattc 44580
ctttttgaga aaaattggcg ataagtttca aactgttgac ttcactgatt gtcgcactat 44640
agatgcaatc aacaagtgtg tagatatctt tactgagggg aaaatcaatc cactattgga 44700
tgaacaattg tctcctagca attagtgccg tatactttaa agcaaaatgg ttgacgccat 44760
tcgaaaagga atttaccagt gattatccct tttacgtatc accaacggaa atggtagacg 44820
taagtatgat gtctatgtac ggcgagctat ttaatcacgc atctgtaaaa gaatcattcg 44880
gtaacttttc aatcatagaa ctgccatatg ttggagatac tagtatgatg gtcattcttc 44940
cagacaagat tgatggatta gaatccatag aacaaaatct aacagataca aattttaaga 45000
aatggtgtaa ctctctggaa gctacgttta tcgatgttca cattcccaag tttaaggtaa 45060
caggctcgta taatctggtg gatactctag taaagtcagg actgacagag gtgttcggtt 45120
caactggaga ttatagcaat atgtgtaatt tagatgtgag tgtcgacgct atgatccaca 45180
aaacgtatat agatgtcaat gaagagtata cagaagcagc tgcagcaact tgtgcactgg 45240
tgtcagactg tgcatcaaca attacaaatg agttctgtgt agatcatccg ttcatctatg 45300
tgattaggca tgttgatgga aaaatttttt tcgttggtag atattgctct ccgacaacta 45360
attgttaacc atttttttta aaaaaataga aaaaacatgt ggtattagtg caggtcgtta 45420
ttcttccaat tgcaattggt aagatgacgg ccaactttag tacccacgtc ttttcaccac 45480
agcactgtgg atgtgacaga ctgaccagta ttgatgacgt caaacaatgt ttgactgaat 45540
atatttattg gtcgtcctat gcataccgca acaggcaatg cgctggacaa ttgtattcca 45600
cactcctctc ttttagagat gatgcggaat tagtgttcat cgacattcgc gagctggtaa 45660
aaaatatgcc gtgggatgat gtcaaagatt gtgtagaaat catccgttgt tatataccgg 45720
atgagcaaaa aaccatcatc ggactttgtg catatgctgc tacttactgg ggaggtgaag 45780
accatcccac tagtaacagt ctgaacgcat tgtttgtgat gcttgagatg ctaaattacg 45840
tggattataa catcatattc cggcgtatga attgatgagt tgtacatctt gacattttct 45900
tctttcttct cttctccctt tcccagaaac aaactttttt tacccactat aaaataaaat 45960
gagtatacta cctgttatat ttctttctat atttttttat tcttcattcg ttcagacttt 46020
taacgcgcct gaatgtatcg acaaagggca atattttgca tcattcatgg agttagaaaa 46080
cgagccagta atcttaccat gtcctcaaat aaatacgcta tcatccggat ataatatatt 46140
agatatttta tgggaaaaac gaggagcgga taatgataga attataccga tagataatgg 46200
tagcaatatg ctaattctga acccgacaca atcagactct ggtatttata tatgcattac 46260
cacgaacgaa acctactgtg acatgatgtc gttaaatttg acaatcgtgt ctgtctcaga 46320
atcaaatata gatcttatct cgtatccaca aatagtaaat gagagatcta ctggcgaaat 46380
ggtatgtccc aatattaatg catttattgc tagtaacgta aacgcagata ttatatggag 46440
cgggcatcga cgccttagaa ataagagact taaacaacgg acacctggaa ttattaccat 46500
agaagatgtt agaaaaaatg atgctggtta ttatacatgt gttttagaat atatatacgg 46560
tggcaaaaca tataacgtaa ccagaattgt aaaattagag gtacgggata aaataatacc 46620
ttctactatg caattaccag aaggtgttgt aacttcaata ggtagtaatt tgactattgc 46680
gtgtagagta tcgttgagac ctcccacaac ggatgcagac gtcttttgga taagtaatgg 46740
tatgtattac gaagaagatg atggggacgg agacggtaga ataagtgtag caaataaaat 46800
ctatatgacc gataagagac gtgttattac atcccggtta aacattaatc ctgtcaagga 46860
agaagatgct acaacgttta cgtgtatggc gtttactatt cctagcatca gcaaaacagt 46920
tactgttagt ataacgtgaa tgtatgttgt tacatttcca tgtcaattga gtttataaga 46980
atttttatac attatcttcc aacaaacaat tgacgaacgt attgctatga ttaactccca 47040
cgatactatg catattatta atcattaact tgcagactat acctagtgct attttgacat 47100
actcatgttc ttgtgtaatt gcggtatcta tattattaaa gtacgtaaat ctagctatag 47160
ttttattatt taattttaga taatataccg tctccttatt tttaaaaatt gccacatcct 47220
ttattaaatc atgaatggga atttctatgt catcgttaat atattgtgaa caacaagagc 47280
agatatctat aggaaagggt ggaatgcgat acattgatct atgtagtttt aaaacacacg 47340
cgaactttga agaatttata taaatcattc catcgataca tccttctatg ttgacatgta 47400
tatatccagg aattctttta ttaatgtcag gaaatgtata aactaaaaca ttgcccgaaa 47460
gcggtgcctc tatctgcgtt atatccgttc ttaacttaca aaatgtaacc aatacctttg 47520
catgacttgt tttgttcggc aacgttagtt taaacttgac gaatggatta attacaatag 47580
catgatccgc gcatctatta agttttttta ctttaacgcc cttgtatgtt tttacagaga 47640
ctttatctaa atttctagtg cttgtatgtg ttataaatat aacgggatat agaactgaat 47700
cacctacctt agatacccaa ttacatttta tcagatccag ataataaaca aattttgtcg 47760
ccctaactaa ttctatattg ttatatattt tacaattggt tatgatatca tgtaataact 47820
tggagtctaa cgcgcatcgt cgtacgttta tacaattgtg atttagtgta gtatatctac 47880
acatgtattt ttccgcacta tagtattctg gactagtgat aaaactatcg ttatatctgt 47940
cttcaatgaa ctcatcgaga tattgctctc tgtcatattc atacacctgc ataaactttc 48000
tagacatctt acaatccgtg ttattttagg atcatattta catatttacg ggtatatcaa 48060
agatgttaga ttagttaatg ggaatcgtct ataataatga atattaaaca attatatgag 48120
gacttttacc acaaagcatc ataaaaatga gtcgtcgtct gatttatgtt ttaaatatca 48180
accgcgaatc aactcataaa atacaagaga atgaaatata tacatatttt agtcattgca 48240
atatagacca tacttctaca gaacttgatt ttgtagttaa aaactatgat ctaaacagac 48300
gacaacctgt aactgggtat actgcactac actgctattt gtataataat tactttacaa 48360
acgatgtact gaagatatta ttaaatcatg gagtggatgt aacgatgaaa accagtagcg 48420
gacgtatgcc tgtttatata ttgcttacta gatgttgtaa tatttcacat gatgtagtga 48480
tagatatgat agacaaagat aaaaaccact tatcgcatag agactattcc aacctactac 48540
tagagtatat aaaatctcgt tacatgttat tgaaggaaga ggatatcgat gagaacatag 48600
tatccacttt attagataag ggaatcgatc ctaactttaa acaagacgga tatacagcgt 48660
tacattatta ttatttgtgt ctcgcacacg tttataaacc aggtgagtgt agaaaaccga 48720
taacgataaa aaaggccaag cgaattattt ctttgtttat acaacatgga gctaatctaa 48780
acgcgttaga taattgtggt aatacaccat tccatttgta tcttagtatt gaaatgtgta 48840
ataatattca tatgactaaa atgctgttga cttttaatcc gaatttcaaa atatgtaata 48900
atcatggatt aacgcctata ctatgttata taacttccga ctacatacaa cacgatattc 48960
ttgttatgtt aatacatcac tatgaaacaa atgttggaga aatgccgata gatgagcgtc 49020
gtataatcgt attcgagttt atcaaaacat attctacacg tccggcagat tcgataactt 49080
atttgatgaa taggtttaaa aatatagata tttatacccg ctatgaagga aagacattat 49140
tacacgtagc atgtgaatat aataatacac acgtaataga ttatcttata cgtatcaacg 49200
gagatataaa tgcgttaacc gacaataaca aacacgctac acaactcatt atagataaca 49260
aagaaaattc cccatatacc attaattgtt tactgtatat acttagatat attgtagata 49320
agaatgtgat aagatcgttg gtggatcaac ttccatctct acctatcttc gatataaaat 49380
catttgagaa attcatatcc tactgtatac ttttagatga cacattttac aatagacacg 49440
ttaggaatcg caattctaaa acgtatcgat acgcattttc aaaatacatg tcgtttgata 49500
aatacgatgg tataataact aaatgtcata aagaaacaat attgctcaaa ctatccactg 49560
ttctagacac tacactatat gcagttttaa gatgccataa ttcgaaaaag ttaagaagat 49620
acctcaacga gttaaaaaaa tataataacg ataagtcctt taaaatatat tctaatatta 49680
tgaatgagag ataccttaat gtatattata aagatatgta cgtgtcaaag gtatatgata 49740
aactatttcc tgttttcaca gataaaaatt gtctactaac attactacct tcagaaatta 49800
tatacgaaat attatacatg ctgacaatta acgatcttta taatatatcg tatccaccta 49860
ccaaagtata gttgtatttt tctcatgcga tgtgtgtaaa aaaactgata ttatataaat 49920
attttagtgc cgtataatga agatgacgat gaaaatgatg gtacatatat atttcgtatc 49980
attattgtta ttgctattcc acagttacgc catagacatc gaaaatgaaa tcacagaatt 50040
cttcaataaa atgagagata ctctaccagc taaagactct aaatggttga atccagcatg 50100
tatgttcgga ggcacaatga atgatatagc cgctctagga gagccattca gcgcaaagtg 50160
tcctcctatt gaagacagtc ttttatcgca cagatataaa gactatgtgg ttaaatggga 50220
gaggctagaa aaaaatagac ggcgacaggt ttctaataaa cgtgttaaac atggtgattt 50280
atggatagcc aactatacat ctaaattcag taaccgtagg tatttgtgta ccgtaactac 50340
aaagaatggt gactgtgttc agggtatagt tagatctcat attaaaaaac ctccttcatg 50400
cattccaaaa acatatgaac taggtactca tgataagtat ggcatagact tatactgtgg 50460
aattctttac gcaaaacatt ataataatat aacttggtat aaagataata aggaaattaa 50520
tatcgacgat attaagtatt cacaaacggg aaagaaatta attattcata atccagagtt 50580
agaagatagt ggaagataca actgttacgt tcattacgac gacgttagaa tcaagatgta 50640
aaatacttac ggttataccg tcgcaagacc acaggtttaa actaatacta gatccaaaaa 50700
tcaacgtaac gataggagaa cctgccaata taacatgcac tgctgtgtca acgtcattat 50760
tgattgacga tgtactgatt gaatgggaaa atccatccgg atggcttata ggattcgatt 50820
ttgatgtata ctctgtttta actagtagag gcggtatcac cgaggcgacc ttgtactttg 50880
aaaatgttac tgaagaatat ataggtaata catataaatg tcgtggacac aactattatt 50940
ttgaaaaaac ccttacaact acagtagtat tggagtaaat acacaatgca tttttatata 51000
cattactgaa taattattat tattatttat atcgtatttg tgctataacg cgactatcta 51060
ggtatttgta tctcaccgat agagaacata taaatgtaga ctctattaaa cagttgtgta 51120
aaatatcaga tcctaataga tgtggatgta cggctttaga aatgagttca ttaaaatatg 51180
tgatatcaac ggaacatatt tatataatta tactattgct gttagtataa ttattgattc 51240
cacggaagaa ctaccaacag ttactccaat tacaacaaca tataattata ctatcgatga 51300
tagcactact gaagaactac aagtgactcc tcatatggat ctccatcgat gatacatgta 51360
ttaaaatact ttccgaataa gtcttttaaa tattgtatta attatgaaaa actatgctat 51420
gcgagtatga tacgatacta gattttatct ctagcgagag atgtcgttag aatcatttat 51480
caacgaatat cgataacatg tgtcatttat acgttaaagt ctgtccgtct tctctattgt 51540
ttagactgtt tgtagaatgc tgtgatataa acaaactagt agacacaaat atttaactca 51600
tgatgaagtt gagaatgata tgctttagct aatataaaaa tatattaatc cactatatat 51660
tctagacttg atttaaaacc gataaactac tactacgtac tgtataagtt aggagcagac 51720
cctaattatg tagatgatag aggtaatact tctgcatcta tatgtccact tatgagaaaa 51780
cgtcatttaa taagatgcat cgtgaaaaga aatttattaa agagttggta aaatatgaaa 51840
ccgaaagtaa ataatatagg aaatacacct ctacataact acgtatctca atatgatatc 51900
actctcattc ctcatccaca acccattaaa aaatggaaat taaagccctc tattagcata 51960
aacggctaca ggtctacctt tacaatggcc tttccttgtg cccagttcag accctgtcat 52020
tgccacgcta ctaaggactc cctgaatacc gtggccgacg tcagacattg tctgactgaa 52080
tacatcctgt gggtttctca tagatggacc catagagaaa gcgcagggtc tctctacagg 52140
cttctcatct ctttcagaac tgatgcaacg gagctctttg gtggtgagtt gaaggattca 52200
cttccgtgga gatcattaaa tgactccatg aaaaccgccg aagaacttcg tgcaatcatt 52260
ggactttgta ctcaatcagc tatcgtctct ggaagagtct tcaacgataa gtatatcgac 52320
atactactta tgctgcgaaa gattctgaac gagaacgact atctcaccct cttggatcat 52380
atccgcactg ctaaatacta aatctccttc atgctctctc actacacttt ttatcatctt 52440
atgaggaata attagcacca gaatagctat ggattgcaca tgtattctat gtcgtctact 52500
ggatgaagat gtgacgtaca aaaaaataaa actagaaatt gaaacgtgtc acaacttatc 52560
aaaacatata gatagacgag gaaacaatgc gctacattgt tacgtctcca ataaatgcga 52620
tacagacatt aagattgttc gactgttact ctctcgcgga gtcgagagac tttgtagaaa 52680
caacgaagga ttaactccgc taggagcata cagtaagcat agatacgtaa aatctcagat 52740
tgtgcatcta ctgatatcca gctattcgaa ttcctctaac gaactcaagt cgaatataaa 52800
tgatttcgac ttacgtctgc taaaatacct aattgtggat aaacggatac gtccgtccaa 52860
gaatacgaat tatgcaatca atggtctcgg attggtggat atatacgtaa cgacgcctaa 52920
tccgagacca gaagtattgc tatggcttct taaatcagaa tgttacagca ccggttacgt 52980
atttcgtacc tgtatgtaca acagtgatat gtgtaagaac tctcttcatt actatatatc 53040
gtctcataga gaatctctat ccaaggatgt aattaaatgt ttgatcgata acaatgtttc 53100
catccaatac tactggtctt gctcaaccat agatatagag attattaata aaggatgtgg 53160
acacgtgtag agtatacgac gtcagcccta tattagaggc gtattatcta aacaagcgat 53220
ttagagtaac cccatataat gtagacatgg aaatcgttaa tcttcttatt gagagacgtc 53280
atactcttgt cgacgtaatg cgtagtatta cttcgtacga ttccagagaa tataaccact 53340
acatcatcga taacattcta aagagattta gacaacagga tgaatccatc gtacaagcca 53400
tactgataaa ctacttacat tacggcgata tggtaagtat acctatcatt caatgcatgt 53460
tggataagac gacggacaac aactttgtta ataataatct cgtcgatgta aacgtcgtaa 53520
ggtttatcgt ggaaaatatg gacacgcggc tgtaaatcac atatctaaca atggccgtct 53580
atgtatgtac ggtctgatat tatcgagatt taataattgc gggtatcact gttatgaaga 53640
tgtatttgat atactaagca agtacatgga tgatatagat atgatcgata actctactat 53700
attacgcggt cgatgtcaat aatatacaat ttgcaaagcg gttattggaa tatggagcga 53760
gtgtcacgct cgataatcaa tacggccatc cagaaaagca gttaccaaag agaagctagt 53820
tgatttatta ctgagttacc atcccactct agagactatg attgacgcat ttaatagaga 53880
tatacgctat ctatatcctg aaccattatt cgcctgtatc agatacgcct taatcctaga 53940
tgatgatttt ccttctaaag taagtatgat atcgccggtc gtcataagga actaaagcgc 54000
tatagagcag acattaatag aatgaagaat gcctacatat caggcgtctc catgtttgat 54060
atattattta aacgaagcaa acgccacaga ttgagatacg caaagaacaa tgagaggatc 54120
gactccatta aataatttat catggagtga taatgtcctg tttccatggc atattacaaa 54180
atcgattccg tccaagatga taaaaacatt taccggcatc ataaacacgg agtttatttt 54240
atatgtctcg cataaacatt actaaaaaaa tatattgttc ggttttcttt cacatcttta 54300
attatgaaaa agtaaatcat tatgagatgg acgcatcgtt cgcgacagta tgtggtacat 54360
acctaacgta tttatggacg acggtaagaa tgaaggtcac gtttctgtca acaatgtcga 54420
cgcgatcgtg taacacgact cacaatagaa tctgtgaatg ctctcccgat catggatgca 54480
aggcatgtgt ttcccaaaca aaatgtggaa taggatacgg agtatccgga gacgtcatct 54540
gttctccgtg tggtctcgga acatattctc acaccgtctc ttccgcagat aaatgcgaac 54600
ccgtacccag aaataccttt aactatatcg atgtggaaat taacctgtat ccagttaacg 54660
acacatcgtg tactcggacg accactaccg gtctcagcga atccatctca acgtcggaac 54720
taactattac tatgaatcat aaagactgcg atcccgtctt cttaataagg tagcgacttc 54780
aggtttcttt acaggagaaa ggtgtgcact ctgaatttcg agattaaatg caataacaaa 54840
gattcttcct ccaaacagtt aacgaaagca aagaatgata ctatcatgcc gcattcggag 54900
acagtaactc tagcgtcgac atctatatac tatatagtaa taccaatact caagactacg 54960
aaactgatac aatctcttat catgtgggta atgtagccat atgcccggta gttgcgatat 55020
acataaactg atcactaatt ccaaacccac ccgcttttta tagtaagttt ttcacccata 55080
aatacaataa ttaatttctc gtaaaagtag aaaatatatt ctaatttatt gcacggtaag 55140
gaagtagaat cataaagaac agtactcaat caatagcaat catgaaacaa tatatcgtac 55200
tggcatgcat gtgcctgcca gtcttcagca atcatcctca tcgtgtacgg aagaagaaaa 55260
caaacatcat atgggaatcg atgttattat caaagtcaca aagcaagacc aaacaccgac 55320
cgatgataag atttgccaat ccgtaacgga aattacagag tccgagtcag atccagatcc 55380
cgaggtggaa tcagtcgagg atgtagatcc tcctaccact tattactcca tcatcggtgg 55440
aggtctgaga atgaactttg gattcaccaa atgtcctcag attaaatcca tctcagaatc 55500
cgctgatgga aagactgtga ggtgtctatc gacatcagat gtagcgaaga agagaaagac 55560
agcgacatca agacccatcc agtactcggg tctaacatct ctcataagaa agtgagttac 55620
gaagatatca tcggttcaac gatcgtcgat acaaaatgtg tcaagaatct agagtttagc 55680
gttcgtatcg gagacatgtg caaggaatca tctgaacttg aggtcaagta tgtcgacgga 55740
tcggcatctg aaggtgcaac cgatgatact tcactcatcg attcaacaaa actcaaagcg 55800
tgtgtctgaa tcgataactc tattcatctg aaattggatg agtagggtta atcgaacgat 55860
tcaggcacac cacgaattaa aaaagtgtac cggacactat attccggttt gcaaaacaaa 55920
aagttacctc tcgcgacttc ttctttttct gtctcaatag tgtgatacga ttatgacact 55980
attcctattt cctttcaggg tatcacaaaa atattaaacc tctttctgat ggtctcatac 56040
aaaaatattt ttattctctt tctctctttg atggtctcat aaaaaatatt tttattctct 56100
ttctctcttt gatggtctca taaaatattt ttattctctt tctctctttg atggtctcat 56160
aaaaaatatt tttattctct ttctctcttt gatggtctca taaaatattt ttattctctt 56220
tctctctttg atggtctcat aaaaaatatt tttattctct ttctctcttt gatggtctca 56280
taaaaaatat taaacctctt tctgatggtg tcactaaaat atttttattc tctttctctc 56340
ttcaatggag tcataaaata tttttattct ctttctctct tcgatggtct cacaaaaata 56400
ttaaacctct ttctgatggt gtcactaaaa tatttttatt ctctttctct cttcaatgga 56460
gtcataaaat atttttattc tctttctctc tttgatggtc tcacaaaaat atttttattc 56520
tctttctctc tttgatggtc tcacaaaaat atttttattc tctttctctc tttgatggtc 56580
tcacaaaaat atttttattc tctttctctc tttgatggtc tcataaaaaa agttttacaa 56640
aaatattttt attctctttc tctctttgat ggtctcataa aaaaagtttt acaaaaatat 56700
ttttattctc tttctctctt tgatggtctc ataaaaaaag ttttacaaaa atatttttat 56760
tctctttctc tctttgatgg tctcataaaa aatattaaac ctctttctga tggtgtcact 56820
aaaatatttt tattctcatt ctctcttcaa tggagtcata aaatattttt attctctttc 56880
tctcttcgat ggtctcacaa aaatattaaa cctctttctg atggtgtcac taaaatattt 56940
ttattctcat tctctcttca atggagtcat aaaatatttt tattctcttt ctctcttcga 57000
tggtctcaca aaaatattaa acctctttct gatggtgtca ctaaaatatt tttattctca 57060
ttctctcttc aatggagtca taaaatattt ttattctctt tctctctttg atggtctcat 57120
aaaaaaagtt ttacaaaaat atttttattc tctttctctc tttgatggtc tcataaaaaa 57180
tattaaacct ctttctgatg gtgtcactaa aatattttta ttctctttct ctcttcaatg 57240
gagtcataaa atatttttat tctctttctc tcttcgatgg tctcacaaaa atattaaacc 57300
tctttctgat ggtgtcacta aaatattttt attctcattc tctcttcaat ggagtcataa 57360
aatattttta ttctctttct ctctttgatg gtctcataaa aaaagtttta caaaaatatt 57420
tttattctct ttctctcttt gatggtctca taaaaaaagt tttacaaaaa tatttttatt 57480
ctctttctct ctttgatggt ctcataaaaa aagttttaca aaaatatttt tattctcttt 57540
ctctctttga tggtctcata aaaaaagttt tacaaaaata tttttattct ctttctctct 57600
ttgatggtct cataaaaaat attaaacctc tttctgatgg tgtcactaaa atatttttat 57660
tctcattctc tcttcaatgg agtcataaaa tatttttatt ctctttctct cttcgatggt 57720
ctcacaaaaa tattaaacct ctttctgatg gtgtcactaa aatattttta ttctcattct 57780
ctcttcaatg gagtcataaa atatttttat tctctttctc tctttgatgg tctcataaaa 57840
aaagttttac aaaaatattt ttattctctt tctctctttg atggtctcat aaaaaaagtt 57900
ttacaaaaat atttttattc tctttctctc tttgatggtc tcataaaaaa agttttacaa 57960
aaatattttt attctctttc tctctttgat ggtctcataa aaaaagtttt acaaaaatat 58020
ttttattctc tttctctctt tgatggtctc acaaaaatat taaacctctt tctgatggag 58080
tcgtaaaaaa gttttatctc tttctccttc gatggtctca caaaaatatt aaacctcttt 58140
ctgatggagt cgtaaaaaag ttttatctct ttctctcttc gatggtctca caaaaatatt 58200
aaacctcttt ctgatggagt cgtaaaaaag ttttatctct ttctctcttc gatggtctca 58260
ctaaaatatt ttttattctc tttctgatgc atcaactatt tcttaaacaa taacgtccaa 58320
caacatatac tcgtcgagct tatcaacatc ccctatgccc atctaggtta ccagacaatt 58380
gtatatcata aaataatgtt tataattttt acaaaaatat ttttattctc tttctctctt 58440
tgatggtctc ataaaaaaag ttttacaaaa atatttttat tctctttctc tctttgatgg 58500
tctcataaaa aatattaaac ctctttctga tggtgtcact aaaatatttt tattctcatt 58560
ctctcttcaa tggagtcata aaatattttt attctctttc tctcttcgat ggtctcacaa 58620
aaatattaaa cctctttctg atggtgtcac taaaatattt ttattctcat tctctcttca 58680
atggagtcat aaaatatttt tattctcttt ctctctttga tggtctcata aaaaaagttt 58740
tacaaaaata tttttattct ctttctctct ttgatggtct cataaaaaaa gttttacaaa 58800
aatattttta ttctctttct ctctttgatg gtctcataaa aaaagtttta caaaaatatt 58860
tttattctct ttctctcttt gatggtctca taaaaaaagt tttacaaaaa tatttttatt 58920
ctctttctct ctttgatggt ctcataaaaa aagttttaca aaaatatttt tattctcttt 58980
ctctctttga tggtctcata aaaaaagttt tacaaaaata tttttattct ctttctctct 59040
ttgatggtct cataaaaaaa gttttacaaa aatattttta ttctctttct ctctttgatg 59100
gtctcataaa aaatattaaa cctctttctg atggtgtcac taaaatattt ttattctctt 59160
tctctcttca atggagtcat aaaatatttt tattctcttt ctctcttcga tggtctcaca 59220
aaaatattaa acctctttct gatggtgtca ctaaaatatt tttattctca ttctctcttc 59280
aatggagtca taaaatattt ttattctctt tctctctttg atggtctcat aaaaaaagtt 59340
ttacaaaaat atttttattc tctttctctc tttgatggtc tcataaaaaa agttttacaa 59400
aaatattttt attctctttc tctctttgat ggtctcataa aaaaagtttt acaaaaatat 59460
ttttattctc tttctctctt tgatggtctc ataaaaaaag ttttacaaaa atatttttat 59520
tctctttctc tctttgatgg tctcataaaa aaagttttac aaaaatattt ttattctctt 59580
tctctctttg atggtctcat aaaaaatatt aaacctcttt ctgatggtgt cactaaaata 59640
tttttattct ctttctctct tcaatggagt cataaaatat ttttattctc tttctctctt 59700
cgatggtctc acaaaaatat taaacctctt tctgatggtg tcactaaaat atttttattc 59760
tctttctctc ttcaatggag tcataaaata tttttattct ctttctctct ttgatggtct 59820
cataaaaaaa gttttacaaa aatattttta ttctctttct ctctttgatg gtctcataaa 59880
aaaagtttta caaaaatatt tttattctct ttctctcttt gatggtctca taaaaaaagt 59940
tttacaaaaa tatttttatt ctctttctct ctttgatggt ctcataaaaa aagttttaca 60000
aaaatatttt tattctcttt ctctctttga tggtctcata aaaaaagttt tacaaaaata 60060
tttttattct ctttctctct ttgatggtct cataaaaaaa gttttacaaa aatattttta 60120
ttctctttct ctctttgatg gtctcataaa aaaagtttta caaaaatatt tttattctct 60180
ttctctcttt gatggtctca taaaaaatat taaacctctt tctgatggtg tcactaaaat 60240
atttttattc tcattttctc tttctctctt caatggagtc ataaaatatt tttattctct 60300
ttctctcttt gatggtctca taaaaaatat taaacctctt tctgatggtg tcactaaaat 60360
atttttattc tcattctctc ttcaatggag tcataaaaaa gttttatctc tttctctctt 60420
cgatggtctc acaaaaatat taaacctctt tctgatggag tcgtaaaaaa gttttatctc 60480
tttctctctt cgatggtctc acaaaaatat taaacctctt tctgatgcat caactatttc 60540
ttaaacaata acgtccaaca acatatactc atcccctatg cccatctagg ttaccagaca 60600
attgtatatc ataaaataat gtttataatt tacacgttaa aatcatataa taaaacgtag 60660
atcgtataat attttttggt atataaatga tctagtaaaa tccatgtagg ggatactgct 60720
cacatttttt ctttggtaca aaatttcaca caagttttta tacagacaaa ttcttgtcca 60780
tatattttaa aacattgact tttgtactaa gaaaaatatc tagactaact atctctttct 60840
ctttctctct tcgatggtct ttctgatgga gtcgtaaaaa agttttatct ctttctctct 60900
tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct 60960
ctttctctct tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa 61020
agttttatct ctttctcctt cgatggtctc acaaaaatat taaacctctt tctgatggag 61080
tcgtaaaaaa gttttatctc tttctctctt cgatggtctc acaaaaatat taaacctctt 61140
tctgatggtg tcactaaaat atttttattc tctttctctc ttcgatggtc tcacaaaaat 61200
attaaacctc tttctgatgg agtcgtaaaa aagttttatc tctttctcct tcgatggtct 61260
cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct ctttctctct 61320
tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct 61380
ctttctcctt cgatggtctc acaaaaatat taaacctctt tctgatggag tcgtaaaaaa 61440
gttttatctc tttctccttc gatggtctca caaaaatatt aaacctcttt ctgatggagt 61500
cgtaaaaaag ttttatctct ttctccttcg atggtctcac aaaaatatta aacctctttc 61560
tgatggagtc gtaaaaaagt tttatctctt tctctcttcg atggtctcac aaaaatatta 61620
aacctctttc tgatggagtc gtaaaaaagt tttatctctt tctctcttcg atggtctcac 61680
aaaaatatta aacctctttc tgatggagtc gtaaaaaagt tttatctctt tctccttcga 61740
tggtctcaca aaaatattaa acctctttct gatggtctct ataaagcgat tgatttttct 61800
taccctctag agtttcctac ggtcgttggt cacacatttt tttctagaca ctaaataaat 61860
agtaagatta aattaattat aaaattatgt atataatatt aattataaaa ttatgtatat 61920
gatttactaa ctttagttag ataaattaat aatacataaa ttttagtata ttaatattat 61980
aaattaataa tacataaatt ttagtatatt aatattatat tttaaatatt tatttagtgt 62040
ctagaaaaaa aggccggcct agcaggcc 62068
<210> 15
<211> 62068
<212> DNA
<213> 人工序列
<220>
<223> sMVA F3
<400> 15
ggcctagcag gccttttttt ctagacacta aataaatagt aagattaaat taattataaa 60
attatgtata taatattaat tataaaatta tgtatatgat ttactaactt tagttagata 120
aattaataat acataaattt tagtatatta atattataaa ttaataatac ataaatttta 180
gtatattaat attatatttt aaatatttat ttagtgtcta gaaaaaaagg ccggccgggt 240
attaataata tctatatttc cagcgttaag tgtaacatta aacagtttta attcacgtga 300
cgtggtatca attaaataat taatgcccaa tttggatata gcagcctgaa gctcatcttg 360
tttagttacg gatcctaatg agttattaag caatatatcg aacggatgaa cgaaggttgt 420
tttaagttgg tcacatactt tgtaatctag acatagatgc ggaagaacgg tagaaactat 480
acgaaataaa tattcagagt cctctaattg atcaagagta actattgact taataggcat 540
catttattta gtattaaatg acgaccgtac cagtgacgga tatacaaaac gatttaatta 600
cagagttttc agaagataat tatccatcta acaaaaatta tgaaataact cttcgtcaaa 660
tgtctattct aactcacgtt aacaacgtgg tagatagaga acataatgcc gccgtagtgt 720
catctccaga ggaaatatcc tcacaactta atgaagatct atttccagat gatgattctc 780
cggccactat tatcgaacga gtacaacctc atactactat tattgacgat actccacctc 840
ctacgtttcg tagagagtta ttgatatcgg aacaacgtca acaacgagaa aaaagattta 900
atattacagt atcgaaaaat gctgaagcaa taatggaatc tagatctatg atatcttcta 960
tgccaacaca aacaccatcc ttgggagtag tttatgataa agataaaaga attcagatgt 1020
tggaggatga agtggttaat cttagaaatc aacgatctaa tacaaaatca tctgataatt 1080
tagataattt taccagaata ctatttggta agactccgta taaatcaaca gaagttaata 1140
agcgtatagc catcgttaat tatgcaaatt tgaacgggtc tcccttatca gtcgaggact 1200
tggatgtttg ttcagaggat gaaatagata gaatctataa aacgattaaa caatatcacg 1260
aaagtagaaa acgaaaaatt atcgtcacta acgtgattat tattgtcata aatattatcg 1320
agcaagcatt gctaaaactc ggatttgaag aaatcaaagg actgagtacc gatatcactt 1380
cagaaattat cgatgtggag atcggagatg actgcgatgc tgtagcatca aaactaggaa 1440
tcggtaacag tccggttctt aatattgtat tgtttatact caagatattc gttaaacgaa 1500
ttaaaattat ttaatttaat acattcccat atccagacaa caatcgtctg gattaatctg 1560
ttcctgtcgt ctcataccgg acgacatatt aatcttttta ttagtaggca tctttttaga 1620
tggtttcttt ttcccagcat taactgagtc gatacctaga agatcgtgat tgatctctcc 1680
gaccattcca cgaacttcta attggccgtc tctgacggta ccataaacta ttttaccagc 1740
attagtaaca gcttggacaa tctgaccatc catcgcattg tacgatgtag tagtaactgt 1800
tgttctacgt ctaggagcac cagaagtatt tttggagccc ttggatgttg atgtagaaga 1860
agacgaggat tttgattttg gtttacatgt aatacatttt gtatcacatg cgccggcagt 1920
cacatctgtt tgagaattaa gattattgtt gcctcctttg acggctgcat ctccaccgat 1980
ttgcgctagt agatttttaa gctgtggtgt aatcttatta actgtttcga tataatcatc 2040
gtaactgctt ctaacggcta aatttttttt atccgccatt tagaagctaa aaatattttt 2100
atttatgcag aagatttaac tagattatac aatgaactaa tatgatcctt ttccagatta 2160
tttacaaact tggtattttt tggttctgga ggaggcgaat ttaaattcgg acttggattt 2220
ggattttgtg ggttcttgat cttattatac agcgcatata ggatggcgac ggtaactgct 2280
acgcaaatac cgatcaacaa aagaatacca atcatttatt gacaataact tcactattga 2340
tcaagtatgc aatatatcat cttttcacta aataagtagt aataatgatt caacaatgtc 2400
gagatatatg gacgataata atttagttca tggaaatatc gctatgattg gtatgaatga 2460
ctccgctaac tctgtggggc gcgcagtgct ttccccacat agaataaatt agcattccga 2520
ctgtgataat aataccaagt ataaacgcca taatactcaa tactttccat gtacgagtgg 2580
gactggtaga cttactaaag tcaataaagg cgaagataca cgaaagaatc aaaagaatga 2640
ttccagcgat tagcacgccg gaaaaataat ttccaatcat aagcatcata tccatttaac 2700
taataaaaat tttaaatcgc cgaatgaaca aagtggaata taaaccatat aaaaacaata 2760
gtttgtactg caaaaataat atctattttt gttttcgaag atatggtaaa attaaatagt 2820
agtacacagc atgttataac taacagcagc aacggctcgt aattacttat catttactag 2880
acgaaaaggt ggtgggatat tttcttgctc aaataatacg aatatatcac ccatccattt 2940
tatgcgatgt ttatatactc taatctttaa tagatctata gacgacgggt ttaccaacaa 3000
tatagatttt atcgattcat ctaatttaaa cccttcctta aacgtgaatg atctattatc 3060
tggcataacg atgactctac ccgatgaatc ggacaatgta ctgggccatg tagaataaat 3120
tatcaacgaa ttatcgtcta cgaacattta tatcatttgt tttaatttta gtacgcgaat 3180
aaatagatat aaaatagaaa ataacagata ttacaaccaa tgttatggcc gcgcccaacc 3240
aggtaggcag ttttatttta tcttttacta caggttctcc tggatgtacg tcaccaacgg 3300
cggacgtagt tctagtacaa ttagacgtaa gttccgcttg ggaatttttt aacgctaaag 3360
agttaacgtt aatcgtgcac ccaacgtatt tacatctagt tctttgaaca tcttgattat 3420
aatataacca ttttctatct ctagattcgt cggtgcactc atgtaaccaa cataccctag 3480
gtcctaaata tttatctccg gaattagatt ttggataatt cgcgcaccaa caatttctat 3540
ttcctttatg atcgttacaa aagacgtata atgccgtatc cccaaaagta aaataatcag 3600
gacgaataat tctaataaac tcagaacaat atctcgcatc catatgtttg gagcaaatat 3660
cggaataagt agacatagcc ggtttccgtt ttgcacgtaa ccattctaaa caattggggt 3720
ttccaggatc gtttctacaa aatccagtca tgaaatcatc acaatgttct gtcttgtaat 3780
tattattaaa tatttttgga cagtgtttgg tatttgtctt agaacaacat tttgccacgc 3840
tatcactatc gcccaggaga taatcctttt ttataaaatg acatcgttgc ccggatgcta 3900
tataatcagt agcgtgtttt aaatccttaa tatattcagg agttacctcg ttctgataat 3960
agattaatga tccaggacga aatttgaaag aactacatgg ttctccatga attaatacat 4020
attgtttagc aaattcagga actataaaac tactacaatg atctatcgac ataccatcta 4080
tcaaacaaaa cttgggttta atttctcccg gagatgtttc ataatagtac gtataacttt 4140
cttctgcaaa cttaacagct ctattatatt caggataatt aaaacctaat tccatatatt 4200
tgtctcgtat atctgctatt cctggtgcta ttttgattct attaagagta acggctgccc 4260
ccatttttaa taatcgtcag tatttaaact gttaaatgtt ggtatatcaa catttacctt 4320
atttcccgca gtataaggtt tgttgcaggt atactgttca ggaatggtta catttatact 4380
ttttctatag tcctgtcttt cgatgttcat cacatatgca aagaacagaa taaacaaaat 4440
aatgtaagaa ataatattaa atatctgtga attcgtaaat acattgattg ccataataat 4500
tacagcagct acaatacata caatagacat tcccacagtg ttgccattac ctccacgata 4560
catttgagtt actaagcaat aggtaataac taagctagta agaggcaata gaaaagatga 4620
gataaatatc atcaatatag agattagagg agggctatat agagccaaga cgaacaaaat 4680
caaaccgagt aacgttctaa catcattatt tttgaagatt cccaaataat cattcattcc 4740
tccataatcg ttttgcatca tacctccatc tttaggcata aacgattgct gctgttcctc 4800
tgtaaataaa tctttatcaa gcactccagc acccgcagag aagtcgtcaa gcatattgta 4860
atatcttaaa taactcattt atatattaaa aaatgtcact attaaagatg gagtataatc 4920
tttatgccga actaaaaaaa atgacttgtg gtcaacccct aagtcttttt aacgaagacg 4980
gggatttcgt agaagttgaa ccgggatcat cctttaagtt tctgatacct aagggatttt 5040
acgcctctcc ttccgtaaag acgagtctag tatttgaaac attaacaacg accgataata 5100
aaattactag tatcaatcca acaaatgcgc caaagttata tcctcttcaa cgcaaagtcg 5160
tatctgaagt agtttctaat atgaggaaaa tgatcgaatc aaaacgtcct ctatacatca 5220
ctcttcactt ggcgtgtgga tttggtaaga ctattaccac gtgttatctt atggctacac 5280
acggtagaaa aaccgtcatt tgcgtaccca ataaaatgtt aatacatcaa tggaagacac 5340
aggtagaggc agtcggattg gaacataaga tatccataga tggagtaagt agtctattaa 5400
aggaactaaa gactcaaagt ccggatgtat taatagtagt cagtagacat ctgacaaacg 5460
atgccttttg taaatatatc aataagcatt atgatttgtt catcttggat gaatcacata 5520
cgtataatct gatgaacaat acagcagtta caagattttt agcgtattat cctccgatga 5580
tgtgttattt tttaactgct acacctagac catctaacag aatttattgt aacagtatta 5640
ttaatattgc caagttatcc gatctaaaaa aaactatcta tgcagtagat agtttttttg 5700
agccatattc cacagataat attagacata tgataaaacg attagatgga ccatctaata 5760
aatatcatat atataccgag aagttattat ctgtagacga gcctagaaat caacttattc 5820
ttaataccct ggtagaagaa ttcaagtcag gaactattaa tcgcatttta gttattacta 5880
aactacgtga acatatggta ttcttctaca aacgattatt agattttttc ggatcagagg 5940
ttgtatttat aggagacgcc caaaatagac gtactccaga tatggtcaaa tcaatcaagg 6000
aactaaatag atttatattc gtatccacct tattttattc cggtactggt ttagatattc 6060
ctagtttgga ttctttgttc atttgctcgg cagtaatcaa caatatgcaa atagagcaat 6120
tactagggag ggtatgtcga gaaacagaac tattagatag gacggtatat gtatttccta 6180
gcacatccat caaagaaata aagtacatga taggaaattt cgttcaacga attattagtc 6240
tgtctgtaga taaactagga tttaaacaaa aaagttatcg gaaacatcaa gaatccgatc 6300
ccacttctgt atgtacaaca tcctccagag aagaacgtgt attaaataga atatttaact 6360
cgcaaaatcg ttaagaagtt taagcgacga tccgcatgct gcgcaggcca gtgtattacc 6420
cctcatagta ttaatataat ccaatgatac ttttgtgatg tcggaaatct taaccaattt 6480
agactgacag gcagaacacg tcatgcaatc atcatcgtca tcgataactg tagtcttggg 6540
cttctttttg cggctcttca ttccggaacg cacattggtg ctatccattt aggtagtaaa 6600
aaataagtca gaatatgccc tatagcacga tcgtgcaaaa cctggtatat cgtctctatc 6660
tttatcacaa tatagtgtat cgacatcttt attattattg acctcgttta tcttggaaca 6720
tggaatggga acatttttgt tatcaacggc cacctttgcc ttaattccag atgttgtaaa 6780
attataacta aacagtctat catcgacaca aatgaaattc ttgtttagac gtttgtagtt 6840
tacgtatgcg gctcgttcgc gtctcatttt ttcagatatt gcaggtacta taatattaaa 6900
aataagaatg aaataacata ggattaaaaa taaagttatc atgacttcta gcgctgattt 6960
aactaactta aaagaattac ttagtctgta caaaagtttg aaattttcag attctgcggc 7020
tatagaaaag tataattctt tggtagaatg gggaacatct acttactgga aaataggcgt 7080
gcaaaaggta gctaatgtcg agacgtcaat atctgattat tatgatgagg taaaaaataa 7140
accgtttaat attgatccgg gctattacat tttcttaccg gtatattttg ggagcgtctt 7200
tatttattcg aagggtaaaa atatggtaga acttggatct ggaaactctt ttcaaatacc 7260
agatgatatg cgaagtgcgt gtaacaaagt attagacagc gataacggaa tagactttct 7320
gagatttgtt ttgttaaaca atagatggat aatggaagat gctatatcaa aatatcagtc 7380
tccagttaat atatttaaac tagctagtga gtacggatta aacataccca aatatttaga 7440
aattgaaata gaggaagaca cattatttga cgacgagtta tactctatta tagaacgctc 7500
tttcgatgat aaatttccaa aaatatccat atcgtatatt aagttgggag aacttaggcg 7560
gcaagttgta gactttttca aattctcatt catgtatatt gagtccatca aggtagatcg 7620
tataggagat aatattttta ttcctagcgt tataacaaaa tcaggaaaaa agatattagt 7680
aaaagatgta gaccatttaa tacgatccaa ggttagagaa catacatttg taaaagtaaa 7740
aaagaaaaac acattttcca ttttatacga ctatgatgga aacggaacag aaactagagg 7800
agaagtaata aaacgaatta tagacactat aggacgagac tattatgtta acggaaagta 7860
tttctctaag gttggtagtg caggcttaaa gcaattgact aataaattag atattaatga 7920
gtgcgcaact gtcgatgagt tagttgatga gattaataaa tccggaactg taaaacgaaa 7980
aataaaaaac caatcagcat ttgatttaag cagagaatgt ttgggatatc cagaagcgga 8040
ttttataacg ttagttaata acatgcggtt caaaatagaa aattgtaagg ttgtaaattt 8100
caatattgaa aatactaatt gtttaaataa cccgagtatt gagactatat atggaaactt 8160
taaccagttc gtctcaatct ttaatatcgt caccgatgtc aaaaaaagat tattcgagtg 8220
aaataatatg cgcctttgat ataggtgcaa aaaatcctgc cagaactgtt ttagaagtca 8280
aggataactc cgttagggta ttggatatat caaaattaga ctggagttct gattgggaaa 8340
ggcacatagc taaagatttg tcacaatatg aatacactac agttcttcta gaacgtcagc 8400
ctagaaggtc gccgtacgtc aaatttatct attttattaa aggcttttta tatcatacat 8460
cggctgccaa agttatttgc gtctcgcctg tcatgtctgg taattcatat agagatcgaa 8520
aaaagagatc ggtcgaagca tttcttgatt ggatggacac attcggattg cgagactccg 8580
ttccggatag acgcaaatta gacgatgtag cggatagttt caatttggct atgagatacg 8640
tattagataa atggaatact aattatacac cttataatag gtgtaaatct agaaattaca 8700
taaaaaaaat gtaataacgt tagtaacgcc attatggata atctatttac ctttctacat 8760
gaaatagaag atagatatgc cagaactatt tttaactttc atctaataag ttgcgatgaa 8820
ataggagata tatatggtct tatgaaagaa cgcatttcct cagaggatat gtttgataat 8880
atagtgtata ataaagatat acatcatgcc attaagaaac tagtgtattg cgacatccaa 8940
cttactaaac acattattaa tcagaatacg tatccggtat ttaacgattc ttcacaagtg 9000
aaatgttgtc attatttcga tataaactca gataatagca atattagctc tcgtacagta 9060
gagatatttg agagggaaaa gtcatctctt gtatcatata ttaaaactac caataagaag 9120
agaaaggtca attatgggga aataaagaaa actgtacatg gaggcactaa tgcaaattac 9180
ttttccggta aaaagtctga tgagtatctg agcactacag tcaggtccaa cattaatcaa 9240
ccttggatca aaaccatttc taagagaatg agagtagata tcattaatca ctctatagta 9300
acgcgtggaa aaagctctat attacaaact atagaaatta tttttactaa tagaacatgt 9360
gtgaaaatat tcaaggattc tactatgcac attattctat ccaaggacaa ggatgaaaag 9420
gggtgtatac acatgattga caaattattc tatgtctatt ataatttatt tctgttgttc 9480
gaggatatca tccaaaacga gtactttaaa gaagtagcta atgttgtaaa ccacgtactc 9540
acggctacgg cattagatga gaaattattc ctaattaaga aaatggctga acacgatgtt 9600
tatggagtta gcaatttcaa aatagggatg tttaacctga catttattaa gtcgttggat 9660
cataccgttt tcccctctct gttagatgag gatagcaaaa taaagttttt taaggggaaa 9720
aagctcaata ttgtagcatt acgatctctg gaggattgta taaattacgt gactaaatcc 9780
gagaatatga tagaaatgat gaaggaaaga tcgactattt taaatagcat agatatagaa 9840
acggaatcgg tagatcgtct aaaagaattg cttctaaaat gaaaaaaaaa cactaattca 9900
gaaatggatc aacgactcgg atataagttt ttggtgcctg atcctaaagc cggagttttt 9960
tatagaccgt tacatttcca atatgtatcg tattctaatt ttatattgca tcgattgcat 10020
gaaatcttga ccgtcaagcg gccactctta tcgtttaaga ataatacaga acgaattatg 10080
atagaaatta gcaatgttaa agtgactcct ccagattact cacctataat cgcgagtatt 10140
aaaggtaaga gttatgacgc attagccacg ttcactgtaa atatctttaa agaggtaatg 10200
accaaagagg gtatatccat cactaaaata agtagttatg agggaaaaga ttctcatttg 10260
ataaaaattc cgctactaat aggatacggg aataaaaatc cacttgatac agccaagtat 10320
cttgttccta atgtcatagg tggagtcttt atcaataaac aatctgtcga aaaagtagga 10380
attaatctag tagaaaagat tacaacatgg ccaaaattta gggttgttaa gccaaactca 10440
ttcactttct cgttttcctc cgtatcccct cctaatgtat taccgacaag atatcgccat 10500
tacaagatat ctctggatat atcacaattg gaagcgttga atatatcatc gacaaagaca 10560
tttataacgg tcaatattgt tttgctgtct caatatttat ctagagtgag tctagaattc 10620
attagacgta gtttatcata cgatatgcct ccagaagttg tctatctagt aaacgcgata 10680
atagatagtg ctaaacgaat tactgaatct attactgact ttaatattga tacatacatt 10740
aatgacctgg tggaagctga acacattaaa caaaaatctc agttaacgat caacgagttc 10800
aaatatgaaa tgctgcataa ctttttacct catatgaact atacacccga tcaactaaag 10860
ggattttata tgatatcttt actaagaaag tttctctact gtatctacca cacttctaga 10920
tatccagata gagattcgat ggtttgtcat cgcatcctaa cgtacggcaa atattttgag 10980
acgttggcac atgatgaatt agagaattac ataggcaaca tccgaaacga tatcatgaac 11040
aatcacaaga acagaggcac ttacgcggta aacattcatg tactaacaac tcctggactt 11100
aatcatgcat tttctagtct attgagtgga aagttcaaaa agtcagacgg tagttatcga 11160
acacatcctc actattcatg gatgcagaat atttctattc ctaggagtgt tggattttat 11220
ccggatcaag taaagatttc aaagatgttt tctgtcagaa aataccatcc aagtcaatat 11280
ctttactttt gttcatcgga cgttccggaa agaggtcctc aggtaggttt agtatctcaa 11340
ttgtctgtct tgagttccat tacaaatata ctaacgtctg agtatttgga tttggaaaag 11400
aaaatttgtg agtatatcag atcatattat aaagatgata taagttactt tgaaacagga 11460
tttccaatca ctatagaaaa tgctctagtc gcatctctta atccaaatat gatatgtgat 11520
tttgtaactg actttagacg tagaaaacgg atgggattct tcggtaactt ggaggtaggt 11580
attactttag ttagggatca catgaatgaa attcgcatta atattggagc gggaagatta 11640
gtcagaccat tcttggttgt ggataacgga gagctcatga tggatgtgtg tccggagtta 11700
gaaagcagat tagacgacat gacattctct gacattcaga aagagtttcc gcatgtcatc 11760
gaaatggtag atatagaaca atttactttt agtaacgtat gtgaatcggt tcaaaaattt 11820
agaatgatgt caaaggatga aagaaagcaa tacgatttat gtgactttcc tgccgaattt 11880
agagatggat atgtagcatc ttcactagtg ggaatcaatc acaattctgg acccagagct 11940
attcttggat gtgctcaagc taaacaagct atctcttgtc tgagctcgga tatacgaaat 12000
aaaatagaca atggaattca tttgatgtat ccagagaggc caatcgtgat tagtaaggct 12060
ttagaaactt caaagattgc ggctaattgc ttcggccaac atgttactat agcattaatg 12120
tcgtacaaag gtatcaatca agaggatgga attatcatca aaaaacaatt tattcagaga 12180
ggcggtctcg atattgttac agccaagaaa catcaagtag aaattccgtt ggaaaacttt 12240
aataacaaag aaagagatag gtctaacgcc tattcaaaat tagaaagtaa tggattagtt 12300
agactgaatg ctttcttgga atccggagac gctatagcac gaaatatctc atcaagaact 12360
cttgaagatg attttgctag agataatcag attagctttg atgtttccga aaaatatacc 12420
gatatgtaca aatctcgcgt tgaacgagta caagtagaac ttactgacaa agttaaggta 12480
cgagtattaa ccatgaaaga aagaagaccc attctaggag acaaatttac cactagaacg 12540
agtcaaaagg gaacagtcgc gtatatcgcg gatgaaacgg aacttccata cgatgaaaat 12600
ggtatcacac cagatgtcat tattaattct acatccatct tctctagaaa aactatatct 12660
atgttgatag aggttatttt aacagccgca tattctgcta agccgtacaa caataaggga 12720
gaaaaccgac ctgtctgttt tcctagtagt aacgaaacat ccatcgatac atatatgcaa 12780
ttcgctaaac aatgttatga gcattcaaat ccgaaattgt ctgatgaaga attatcggat 12840
aaaatctttt gtgaaaagat tctctatgat cctgaaacgg ataagcctta tgcatccaaa 12900
gtattttttg gaccaattta ttacttgcgt ctgaggcatt taactcagga caaggcaacc 12960
gttagatgta gaggtaaaaa gacgaagctc attagacagg cgaatgaggg acgaaaacgt 13020
ggaggaggta tcaagttcgg agaaatggag agagactgtt taatagcgca tggtgcagcc 13080
aatactatta cagaagtttt gaaagattcg gaagaagatt atcaagatgt gtatgtttgt 13140
gaaaattgtg gagacatagc agcacaaatc aagggtatta atacatgtct tagatgttca 13200
aaacttaatc tctctcctct cttaacaaaa attgatacca cgcacgtatc taaagtattt 13260
cttactcaaa tgaacgccag aggcgtaaaa gttaaattag atttcgaacg aaggcctcct 13320
tcgttttata aaccattaga taaagttgat ctcaaaccgt cttttctggt gtaatattct 13380
agtttggtag tagatacata tcaatatcat caaattcgag atccgaatta taaaatgggc 13440
gtggattgtt aactatagaa tcggacgtct gatattcgaa aatctgtgga gttttaggtt 13500
ttggtggagg tgtaactgct acttgggata ctgaagtctg atattcagaa agctggggga 13560
tgttctggtt cgacatccac cgatggtgtc acatcactaa tcggttcggt aacgtctgtg 13620
gacgatggag gcaccacttc tacaggttct ggttctttat cctcagtcat caacggagct 13680
acttcaatgc gaggaaatgt ataatttggt aatggtttct catgtggatc tgaagaagag 13740
gtaagatatc tactagaaag ataccgatca cgttctagtt ctcttttgta gaacttaact 13800
ttttctttct ccgcatctag ttgatattcc aacctcttca cgttcgcatg ggttacctcc 13860
gcagttttta cgagcgattt cacgttcagc cttcatgcgt cttatagcat gaattcgctt 13920
atcgttatcg ggtttagctt ctgtcacctt agcaattcct tttttattaa actctacata 13980
atcatatcca tttctattgt ttgttctaat ataaacgagt atagcatcat tgctaaattt 14040
ttcaatagta tcgaaaacag aatatcctaa accatataat atatattcag gaacactcaa 14100
actaaatgtc caggattctc ctaaatacgt aaactttaat agtgcgaaat cattcaaaaa 14160
tctaccactt atagatagat agatagtaca taaatgcgta tagtagtcta cctatctctt 14220
tattatgaaa accggcatta cgatcatata tgtcgtgata tacctgtgat ccgtttacgt 14280
taaaccataa atacatgggt gatcctataa acatgaattt atttctaatt ctcagagcta 14340
tagttaattg accgtgtaat atttgcttac atgcatactt gatacgatca ttaataagat 14400
ttttatcatt gctcgttatt tcagaatcgt atatataagg agtaccatcg tgattcttac 14460
cagatattat acaaaatact atatataaaa tatattgacc cacgttagta atcatgtaaa 14520
tgtttaacgt tttaaatttt gtattcaatg atccattatc atacgctagc atggtcttat 14580
gatattcatt ctttaaaata taatattgtg ttagccattg cattggggct cctaatggag 14640
attttttatt ctcatccatt ttaggatagg ctttcataaa gtccctaata acttcgtgaa 14700
taatgtttct atgttttcta ctgatgcatg tatttgcttc gattttttta tcccatgttt 14760
catctatcat agatttaaac gcagtaatgc tcgcaacatt aacatcttga accgttggta 14820
caattccgtt ccataaattt ataatgttcg ccatttatat aactcatttt ttgaatatac 14880
ttttaattaa caaaagagtt aagttactca tatggacgcc gtccagtctg aacatcaatc 14940
tttttagcca gagatatcat agccgctctt agagtttcag cgtgattttc caacctaaat 15000
agaacttcat cgttgcgttt acaacacttt tctatttgtt caaactttgt tgttacatta 15060
gtaatctttt tttccaaatt agttagccgt tgtttgagag tttcctcatt gtcgtcttca 15120
tcggctttaa caattgcttc gcgtttagcc tctggctttt tagcagccgt tgtagaaaaa 15180
aattcagttg ctggaattgc aagatcgtca tctccgggga aaagagttcc gtccatttaa 15240
agtacagatt ttagaaactg acactctgcg ttatttatat ttggtacaac acatggatta 15300
taaatattga tgttaataac atcagaaaat gtaaagtcta tacattgttg catcgtgtta 15360
aattttctaa tggatctagt attattgggt ccaacttctg cctgaaatcc aaatatggaa 15420
gcggatacaa aaccgtttcc tggataaacc acacatctcc acttttgctt tacatcagaa 15480
attgtgtcgt tgacatcttg aactctccta tctaatgccg gtgttccacc tatagatttt 15540
gaatattcga atgctgcatg agtagcatta aattccttaa tattgccata attttcatat 15600
attgagtaac cctggataaa aagtaaacac accgcagccg tagctaccac aataaaaaaa 15660
attgatagag agttcattta taatctatta gaagctgaca aaattttttt acacgcatca 15720
gacaatgctt taataaatag ttcaacatct acttttgtca tatcgaaccg atggtatgat 15780
tctaacctag aattacatcc gaaaaagttg actatgttca tagtcattaa gtcattaaca 15840
aacaacattc cagactctgg attataagac gatactgttt cgtcacaatt acctacctta 15900
atcatgtgat tatgaatatt ggctattaga gcaccttcta agaaatctat aatatctttg 15960
aaacacgatt taaaatcaaa ccacgaatat acttctacga agaaagttag tttacccata 16020
ggagaaataa ctataaatgg agatctaaat acaaaatccg gatctatgat agttttaaca 16080
ttattatatt ctctattaaa tacctccaca tctaaaaatg ttaattttga aactatgtct 16140
tcgtttatta ccgtacctga actaaacgct ataagctcta ttgtttgaga actctttaaa 16200
cgatattctt gaaatacatg taacaaagtt tcctttaact cggtcggttt atctaccata 16260
gttacagaat ttgtatcctt atctataata taataatcaa aatcgtataa agttatataa 16320
ttatcgcgtt cagattggga tcttttcaaa tagactaaaa accccatttc tctagtaagt 16380
atcttatgta tatgtttgta aaatatcttc atggtgggaa tatgctctac cgcagttagc 16440
cattcctcat tgacagcggt agatgtatta gacaaaacta ttccaatgtt taacaagggc 16500
cattttacga gattattaaa tccttgtttg ataaatgtag ccaatgaggg ttcgagttca 16560
acgacgattg aattctcttc ccgcggatgc tgcatgatga acgacgggat gttgttcgat 16620
tgatttggaa ttctttttcg actttttgtt tatattaaat attttaaaat ttatagcgga 16680
tagcaattca tgtaccacgg ataatgtaga cgcgtattgc gcatcgatat ctttattatt 16740
agataaattt atcaataaat gtgagaagtt tgcctcgtta aggtcttcca tttaaatatt 16800
atataaacat ttgtgtttgt atcttattcg tcttttatgg aatagttttt tactagtaaa 16860
gctgcaatta cacactttgt ccgtaaaaca taaatataaa caccagcttt tatcaatcgt 16920
tccaaaaagt cgacggcgga catttttaac atggcatcta ttttaaatac acttaggttt 16980
ttggaaaaaa catcatttta taattgtaac gattcaataa ctaaagaaaa gattaagatt 17040
aaacataagg gaatgtcatt tgtattttat aagccaaagc attctaccgt tgttaaatac 17100
ttgtctggag gaggtatata tcatgatgat ttggttgtat tggggaaggt aacaattaat 17160
gatctaaaga tgatgctatt ttacatggat ttatcatatc atggagtgac aagtagtgga 17220
acaatttaca aattgggatc gtctatcgat agactttctc taaataggac tattgttaca 17280
aaagttaata attataatta tgatacattt tttgacgatg atgattgatc gctattgcac 17340
aattttgttt ttttactttc taatatagcg tttagattct ttttcatgtg cgaatattga 17400
tttactaaaa tatctatgtt taacttttgt tctataacgt ccttatcggc ggtatcggta 17460
catatacgta attcaccttc acaaaatacg gagtcttcga taataatagc caatcgatta 17520
ttggatctag ctgtctgtat catattcaac atgtttaata tatcctttcg tttccccttt 17580
acaggcatcg atcgtagcat attttccgcg tctgagatgg aaatgttaaa actacaaaaa 17640
tgcgtaatgt tagcccgtcc taatattggt acgtgtctat aagtttggca tagtagaata 17700
atagacgtgt ttaaatgcct tccaaagttt aagaattcta ttagagtatt gcattttgat 17760
agtttatcgc ctacatcatc aaaaataagt aaaaagtgtg ctgatttttt atgattttgt 17820
gcgacagcaa tacatttttc tatgttactt ttagttcgta tcagattata ttctagagat 17880
tcctgactac taacgaaatt aatatgattt ggccaaatgt atccatcata atctggatta 17940
taaacgggtg taaacaagaa tacatgttta tattttttaa ctagtgtaga aaacagagat 18000
agtaaataga tagtttttcc agatccagat cctcccgtta aaaccattct aaacggcatt 18060
tttaataaat tttctcttga aaattgtttt tcttggaaac aattcataat tatatttaca 18120
gttactaaat taatttgata ataaatcaaa atatggaaaa ctaaggtcgt tagtagggag 18180
gagaacaaag aaggcacatc gtgacataaa taacatttat tatcatgatg acaccagaaa 18240
acgacgaaga gcagacatct gtgttctccg ctactgttta cagagacaaa attcagggaa 18300
agaataaacg caaacgcgtg attggtctat gtattagaat atctatggtt atttcactac 18360
tatctatgat taccatgtcc gcgtttctca tagtgcgcct aaatcaatgc atgtctgcta 18420
acgaggctgc tattactgac gccgctgttg ccgttgctgc tgcatcatct actcatagaa 18480
aggttgcgtc tagcactacg caatatgatc acaaagaaag ctgtaatggt ttatattacc 18540
agggttcttg ttatatatta cattcagact accagttatt ctcggatgct aaagcaaatt 18600
gcactgcgga atcatcaaca ctacccaata aatccgatgt cttgactacc tggctcattg 18660
attatgttaa ggatacatgg ggatctgatg gtaatccaat tacaaaaact acatccgatt 18720
atcaagattc tgatgtatca caagaagtta gaaagtattt ttgtgttaaa acaatgaact 18780
aatatttatt tttgtacatt aataaatgaa atcgcttaat agacaaactg taagtaggtt 18840
taagaagttg tcggtgccgg tcgctataat gatgatactc tcaaccatta ttagtggcat 18900
aggaacattt ctgcattaca aagaagaact gatgcctagt gcttgcgcca atggatggat 18960
acaatacgat aaacattgtt atttagatac taacattaaa atgtctacag ataatgcggt 19020
ttatcagtgt cgtaaattac gagccagatt gcctagaccg gatactagac atctgagagt 19080
attgtttagt attttttata aagattattg ggtaagttta aaaaagacca atgataaatg 19140
gttagatatt aataatgata aagatataga tattagtaaa ttaacaaatt ttaaacaact 19200
aaacagtacg acggatgctg aagcgtgtta tatatacaag tctggaaaac tggttaaaac 19260
agtatgtaaa agtactcaat ctgtactatg tgttaaaaaa ttctacaagt gacaacaaaa 19320
aatgaattaa taataagtcg ttaacgtacg ccgccatgga cgccgcgttt gttattactc 19380
caatgggtgt gttgactata acagatacat tgtatgatga tctcgatatc tcaatcatgg 19440
actttatagg accatacatt ataggtaaca taaaaactgt ccaaatagat gtacgggata 19500
taaaatattc cgacatgcaa aaatgctact ttagctataa gggtaaaata gttcctcagg 19560
attctaatga tttggctaga ttcaacattt atagcatttg tgccgcatac agatcaaaaa 19620
ataccatcat catagcatgc gactatgata tcatgttaga tatagaagat aaacatcagc 19680
cattttatct attcccatct attgatgttt ttaacgctac aatcatagaa gcgtataacc 19740
tgtatacagc tggagattat catctaatca tcaatccttc agataatctg aaaatgaaat 19800
tgtcgtttaa ttcttcattc tgcatatcag acggcaatgg atggatcata attgatggga 19860
aatgcaatag taatttttta tcataaaagt tgtaaagtaa ataataaaac aataaatatt 19920
gaactagtag tacgtatatt gagcaatcag aaatgatgct ggtacctctt atcacggtga 19980
ccgtagttgc gggaacaata ttagtatgtt atatattata tatttgtagg aaaaagatac 20040
gtactgtcta taatgacaat aaaattatca tgacaaaatt aaaaaagata aagagttcta 20100
attccagcaa atctagtaaa tcaactgata gcgaatcaga ctgggaggat cactgtagtg 20160
ctatggaaca aaacaatgac gtagataata tttctaggaa tgagatattg gacgatgata 20220
gcttcgctgg tagtttaata tgggataacg aatccaatgt tatggcgcct agcacagaac 20280
acatttacga tagtgttgct ggaagcacgc tgctaataaa taatgatcgt aatgaacaga 20340
ctatttatca gaacactaca gtagtactta atgaagatac caaacagaat cctaactatt 20400
catccaatcc tttcgtaaat tataataaaa ccagtatttg tagcaagtca aatccgttca 20460
ttacagaact caacaataaa tttagtgaga ataatccgtt tagacgagca catagcgatg 20520
attatcttaa taagcaagaa caagatcatg aacacgatga tatagaatca ttggtgtgat 20580
tagtttcctt tttataaaat tgaagtaata tttagtatta ttgctgccgt cacgttgtac 20640
aaatggagat attccctgta ttcggcattt ctaaaattag caattttatt gctaataatg 20700
actgtagata ttatatagat acagaacatc aaaaaattat atctgatgag atcaatagac 20760
agatggatga aacggtactt cttaccaaca tcttaagcgt agaagttgta aatgacaatg 20820
agatgtacca tcttattcct catagattat cgacgattat actctgtatt agttctgtcg 20880
gaggatgtgt tatctctata gataatgacg tcaatggcaa aaatattcta acctttccca 20940
ttgatcatgc tgtaatcata tccccactga gtaaatgtgt cgtagttagc aagggtccta 21000
caaccatatt ggttgttaaa gcggatatac ctagcaaacg attggtaaca tcgtttacaa 21060
acgacatact gtatgtaaac aatctatcac tgattaatta ttcgccgttg tctgtattca 21120
ttattagacg agttaccgac tatttggata gacacatatg cgatcagata tttgcgaata 21180
ataagtggta ttccattata accatcgaca ataagcagtt tcctattcca tcaaactgta 21240
taggtatgtc ctctgccaag tacataaatt ctagcatcga gcaagatact ttaatacatg 21300
tttgtaacct cgagcatcca ttcgacttag tatacaaaaa aatgcagtcg tacaattctg 21360
tacctatcaa ggaacaaata ttgtacggta gaattgataa tataaatatg agcattagta 21420
tttctgtgga ttaatagatt tctagtatgg ggatcattaa tcatctctaa tctctaaata 21480
cctcataaaa cgaaaaaaaa gctattatca aatactgtac ggaatggatt cattctcttc 21540
tctttttatg aaactctgtt gtatatctac tgataaaact ggaagcaaaa aatctgataa 21600
aaagaataag aataagatca aggattatta taaaataaca atagttcctg gttcctcttc 21660
cacgtctact agctcgtggt attatacaca tgcctagtaa tagtctcttt gcgttgacgg 21720
aaagcagact agaaataaca ggctaaaatg ttcagacacc ataatagttc ccaacccaga 21780
taataacaga gtaccatcaa cacattcctt taaactcaat cccaaaccca aaaccgttaa 21840
aatgtatccg gccaattgat agtagataat gaggtgtaca gcgcatgatg atttacacag 21900
taaccaaaat gaaaatactt tagtaattat aagaaatata gatggtaacg tcatcatcaa 21960
caatccaata atatgccgga gagtaaacat tgacggataa aacaaaaatg ctccgcataa 22020
ctctatcatg gcaataacac aaccaaatac ttgtaagatt cctaaattag tagaaaatac 22080
aacggatatc gatgtataag tgatctcgag aaataataag aataaagtaa tgcccgtaaa 22140
gataaacatc aacattgttt ggtaatcatt aaaccaatta gtatgaagtt gaactaattt 22200
cacagtagat tttattccag tattatcccc gcatgtataa gtacctggta agatatcttt 22260
atattccata atcaatgaga catcactatc tgataacgaa tgaagtctag cactagtatg 22320
ccatttactt aatattgtcg tcttggaagt tttattataa gttaaaatat catggttatc 22380
caatttccat ctaatatact ttgtcggatt atctatagta cacggaataa tgatggtatc 22440
attacatgct gtatactcta tggtctttgt agttgttata acaaccaacg tatagaggta 22500
tatcaacgat attctaactc ttgacatttt ttatttattt aaaatgatac ctttgttatt 22560
tattttattc tattttgcta acggtattga atggcataag tttgaaacga gtgaagaaat 22620
aatttctact tacttattag acgacgtatt atacacgggt gttaatgggg cggtatacac 22680
attttcaaat aataaactaa acaaaactgg tttaactaat aataattata taacaacatc 22740
tataaaagta gaggatgcgg aaccaataac ggaaatccca aatgttggaa aatagacggt 22800
tcagacgacc caaaacatag aggtagagga tacgctcctt atcaaaatag caaagtaacg 22860
ataatcagtc acaacggatg tgtactatct gacataaaca tatcaaaaga aggaattaaa 22920
cgatggagaa gatttgacgg accatgtggt tatgatttat acacggcgga taacgtaatt 22980
ccaaaagatg gtttacgagg agcattcgtc gataaagatg gtacttatga caaagtttac 23040
attcttttca ctgatactat cggctcaaag agaattgtca aaattccgta tatagcacaa 23100
atgtgcctaa acgacgaagg tggtccatca tcattgtcta gtcatagatg gtcgacgttt 23160
ctcaaagtcg aattagaatg tgatatcgac ggaagaagtt atagacaaat tattcattct 23220
agaactataa aaacagataa tgatacgata ctatatgtat tcttcgatag tccttattcc 23280
aagtccgcat tatgtaccta ttctatgaat accattaaac aatctttttc tacgtcaaaa 23340
ttggaaggat atacaaagca attgccgtct ccagctcctg gtatatgttt accagctgga 23400
aaagttgttc cacataccac gtttgaagtc atagaaaaat ataatgtact agatgatatt 23460
ataaagcctt tatctaacca acctatcttc gaaggaccgt ctggtgttaa atggttcgat 23520
ataaaggaga aggaaaatga acatcgggaa tatagaatat acttcataaa agaaaattct 23580
atatattcgt tcgatacaaa atctaaacaa actcgtagct cgcaagtcga tgcgcgacta 23640
ttttcagtaa tggtaacttc gaaaccgtta tttatagcag atatagggat aggagtagga 23700
atgccacaaa tgaaaaaaat acttaaaatg taatcttaat cgagtacacc gcacgacaat 23760
gaacaaacat aagacagatt atgctggtta tgcttgctgc gtaatatgcg gtctaattgt 23820
tggaattatt tttacagcga cactattaaa agttgtagaa cgtaaattag ttcatacacc 23880
atcaatagat aaaacgataa aagatgcata tattagagaa gattgtccta ctgactggat 23940
aagctataat aataaatgta tccatttatc tactgatcga aaaacctggg aggaaggacg 24000
taatgcatgc aaagctctaa atccaaattc ggatctaatt aagatagaga ctccaaacga 24060
gttaagtttt ttaagaagca ttagacgcgg atattgggta ggagaatccg aaatattaaa 24120
ccagacaacc ccatataatt ttatagctaa aaatgccacg aagaatggaa ctaaaaaacg 24180
gaaatatatt tgtagtacaa cgaatactcc caaactacat ttttatcata ccactacttc 24240
ggttagatgt tttagaaaaa aataaatatc gccgtaccgt tcttgttttt ataaaaataa 24300
caattaacaa ttatcaaatt ttttctttaa tattttacgt ggttgaccat tcttggtggt 24360
aaaataatct cttagtgttg gaatggaatg ctgtttaatg tttccgcact catcgtatat 24420
tttgacgtat gcagtcacat cgtttacgca atagtcagac tgtagttcta tcatgcttcc 24480
tacatcagaa ggaggaacag ttttaaagtc tcttggtttt aatctattgc cattagtttt 24540
catgaaatcc tttgttttat ccacttcaca ttttaaataa atgtccacta tacattcttc 24600
tgttaatttt actagatcgt catgggtcat agaatttata ggttccgtag tccatggatc 24660
caaactagca aacttcgcgt atacggtatc gcgattagtg tatacaccaa ctgtatgaaa 24720
attaagaaaa cagtttaata aatcaacaga aatatttaat cctccgtttg atacagatgc 24780
gccatattta tggatttcgg attcacacgt tgtttgtctg aggtgttcgt ctagtgttgc 24840
ttctacgtaa acttcgattc ccatatattc tttattgtca gaatcgcata ccgatttatc 24900
atcatacact gtttgaaaac taaatggtat acacatcaaa ataataaata ataacgagta 24960
cattctgcaa tattgttatc gtaattggaa aaatagtgtt cgagtgagtt ggattatgtg 25020
agtattggat tgtatatttt attttatatt ttatattttg tagtaagaat agaatgctaa 25080
tgtcaagttt attccaatag atgtcttatt aaaaaacata tataataaat aacaatggct 25140
gaatggcata aaattatcga ggatatctca aaaaataata agttcgagga tgccgccatc 25200
gttgattaca agactacaaa gaatgttcta gctgctattc ctaacagaac atttgccaag 25260
attaatcctc tcatcactaa tcgtaatatt ctaaaacctc ttattggtca gaaatattgt 25320
attgtatata ctaactctct aatggatgag aacacgtatg ctatggagtt gcttactggg 25380
tacgcccctg tatctccgat cgttatagcg agaactcata ccgcacttat atttttgatg 25440
ggtaagccaa caacatccag acgtgacgtg tatagaacgt gtagagatca cgctacccgt 25500
gtacgtgcaa ctggtaatta aaataaaaag taatattcat atgtagtgtc aattttaaat 25560
gatgatgatg aaatggataa tatccatatt gacgatgtca ataatgccgg tattggcata 25620
cagttcatcg atttttagat ttcattcaga ggatgtggaa ttatgttatg ggcatttgta 25680
ttttgatagg atctataatg tagtaaatat aaaatataat ccgcatattc catatagata 25740
taattttatt aatcgcacgt taaccgtaga tgaactagac gataatgtct tttttacaca 25800
tggttatttt ttaaaacaca aatatggttc acttaatcct agtttgattg tctcattatc 25860
aggaaactta aaatataatg atatacaatg ctcagtaaat gtatcgtgtc tcattaaaaa 25920
tttggcaacg agtacatcta ctatattaac atctaaacat aagacttatt ctctacatcg 25980
gtccacgtgt attactataa taggatacga ttctattata tggtataaag atataaatga 26040
catctatgat tttactgcaa tatgtatgct aatagcgtct acattgatag tgaccatata 26100
cgtgtttaaa aaaataaaaa tgaactctta attatgctat gctattagaa atggataaaa 26160
tcaaaattac ggttgattca aaaattggta atgttgttac catatcgtat aacttggaaa 26220
agataactat tgatgtcaca cctaaaaaga aaaaagaaaa ggatgtatta ttagcgcaat 26280
cagttgctgt cgaagaggca aaagatgtca aggtagaaga aaaaaatatt atcgatattg 26340
aagatgacga tgatatggat gtagaaagcg cataatacga tctataaaaa taagtatata 26400
aatacttttt atttactgta ctcttactgt gtagtggtga taccctactc gattattttt 26460
ttaaaaaaaa atacttattc tgattcttct agccatttcc gtgttcgttc gaatgccaca 26520
tcgacgttaa agatagggga gtagttgaaa tctagttctg cattgttggt acgcacctca 26580
aatgtagtgt tggatatctt caacgtatag ttgttgagta gtgatggttt tctaaataga 26640
attctcttca tatcattctt gcacgcgtac atttttagca tccatcttgg aatcctagat 26700
ccttgttcta ttcccaatgg tttcatcaat agaagattaa acatatcgta cgaacacgat 26760
ggagagtaat cgtagcaaaa gtaagcattt cctttaatct cagatcccgg atactggata 26820
tattttgcag ccaacacgtg catccatgca gcatttccta catatacccg gctatgtacc 26880
gcgttatcat cgactgtacg atacataatg ttaccgtgtt gcttacattg ctcgtaaaag 26940
actttcatca atttgtctcc ttctccgtaa attccagtgg gtcttaggca acaagtatac 27000
aattttgctc cattcatgat tacggaatta ttggctttca taaccagttg ctcggccata 27060
cgtttacttt ttgcgtatac atgtcctggt gatatatcat aaagggtatg ctcatggccg 27120
atgaatggat caccgtgttt attgggtcct attgcttcca tgctactagt atagatcaaa 27180
tacttgattc ctaggtccac acaagctgcc aatatagtct gtgttccata atagtttact 27240
ttcatgattt cattatcggt gtattttcca aatacatcca ctagagcagc tgtatgaata 27300
atcagattta ccccatctag cgcttctctt accttatcaa agtcgtttat atcacattgt 27360
atatagttta taaccttaac tttcgaggtt attggttgtg gatcttctac aatatctatg 27420
actctgattt cttgaacatc atctgcacta attaacagtt ttactatata cctgcctaga 27480
aatccggcac caccagtaac cgcgtacacg gccattgctg ccactcataa tatcagacta 27540
cttattctat tttactaaat aatggctgtt tgtataatag accacgataa tatcagagga 27600
gttatttact ttgaaccagt ccatggaaaa gataaagtta ttggattaaa atccggaacg 27660
tatagtttga taattcatcg ttacggagat attagtcaag gatgtgattc cataggcagt 27720
ccagaaatat ttatcggtaa catctttgta aacagatatg gtgtagcata tgtttattta 27780
gatacagatg taaatatatc tacaattatt ggaaaggcgt tatctatttc aaaaaatgat 27840
cagagattag cgtgtggagt tattggtatt tcttacataa atgaaaagat aatacatttt 27900
cttacaatta acgagaatgg cgtttgatat atcagttaat gcgtctaaaa caataaatgc 27960
attagtttac ttttctactc agcaaaataa attagtcata cgtaatgaag ttaatgatac 28020
acactacact gtcgaatttg atagggacaa agtagttgac acgtttattt catataatag 28080
acataatgac tccatagaga taagaggggt gcttccagag gaaactaata ttggttgcgc 28140
ggttaatacg ccggttagta tgacttactt gtataataag tatagtttta aactgatttt 28200
agcagaatat ataagacaca gaaatactat atccggcaat atttattcgg cattgatgac 28260
actagatgat ttggctatta aacagtatgg agacattgat ctattattta atgagaaact 28320
taaagtagac tccgattcgg gactatttga ctttgtcaac tttgtaaagg atatgatatg 28380
ttgtgattct agaatagtag tagctctatc tagtctagta tctaaacatt gggaattgac 28440
aaataaaaaa tataggtgta tggcattagc cgaacatata tctgatagta ttccaatatc 28500
tgagctatct agactacgat acaatctatg taagtatcta cgcgggcaca ctgagagcat 28560
agaggatgaa tttgattatt ttgaagacga tgattcgtct acatgttctg ccgtaaccga 28620
cagggaaacg gatgtataat tttttttata gcgtgaagga tatgataaaa aatataattg 28680
ttgtatttat cccattccaa tcaccttata tgattctgta acacaatgaa ggagtcttat 28740
agatgtatag aggtcagata ctggtttgat aaactgttta ttccacataa gtatgtttga 28800
ctttatggtt agacccgcat actttaacaa atcactgaaa attggagtta ggtattgacc 28860
tctcagaatc agttgccgtt ctggaacatt aaatgtattt tttatgatat actccaacgc 28920
atttatgtgg gcatacaaca agtcattact aatggagtat tccaagagaa gagatttcaa 28980
cagactgttt atgaactcga atgccgcctc attgtcgctt atattgatga tgtcgaattc 29040
tcccaatatc atcaccgatg agtagctcat cttgttatcg ggatccaagt tttctaaaga 29100
tgtcattaaa ccctcgatca tgaatggatt tatcatcatc gtttttatgt tggacatgag 29160
cttagtccgt ttgtccacat ctatagacga cgatttctga attatttcat atatccctct 29220
ctttaactcc aggaacttgt caggatggtc tactttaata tgttctcgtc taagagatga 29280
aaatctttgg atggttgcac gcgacttttc tctaaaggat cctctcttaa atgaatccat 29340
cttatccttg gacaagatgg acagtctatt ttccttagat ggtttaatat ttttgttacc 29400
catgatctat aaaggtagac ctaatcgtct cggatgacca tatatttatt ttcagtttta 29460
ttatacgcat aaattgtaaa aaatatgtta ggtttacaaa aatgtctcgt ggggcattaa 29520
tcgtttttga aggattggac aaatctggaa aaacaacaca atgtatgaac atcatggaat 29580
ctataccggc aaacacgata aaatatctta actttcctca gagatccact gtcactggaa 29640
agatgataga tgactatcta actcgtaaaa aaacctataa tgatcatata gttaatctat 29700
tattttgtgc aaatagatgg gagtttgcat cttttataca agaacaacta gaacagggaa 29760
ttactttaat agttgataga tacgcattct ctggagtagc gtatgccgcc gctaaaggcg 29820
cgtcaatgac tctcagtaag agttatgaat ctggattgcc taaacccgac ttagttatat 29880
tcttggaatc tggtagcaaa gaaattaata gaaacgtcgg cgaggaaatt tatgaagatg 29940
ttacattcca acaaaaggta ttacaagaat ataaaaaaat gattgaagaa ggagatattc 30000
attggcaaat tatttcttct gaattcgagg aagatgtaaa gaaggagttg attaagaata 30060
tagttataga ggctatacac acggttactg gaccagtggg gcaactgtgg atgtaatagt 30120
gaaattacat tttttataaa tggatgaagc atattactct ggcaacttgg aatcagtact 30180
cggatacgtg tccgatatgc ataccgaact cgcatcaata tctcaattag ttattgccaa 30240
gatagaaact atagataatg atatattaaa caaggacatt gtaaatttta tcatgtgtag 30300
atcaaacttg gataatccat ttatctcttt cctagatact gtatatacta ttatagatca 30360
agagatctat cagaccgaat tgattaattc attagacgac aatgaaatta tcgattgtat 30420
agttaacaag tttatgagct tttataagga taacctagaa aatatagtag atgctatcat 30480
tactctaaaa tatataatga ataatccaga ttttaaaact acgtatgccg aagtactcgg 30540
ttccagaata gcggatatag atattaaaca agtgatacgt gagaatatac tacaattgtc 30600
taataatatc cgcgaacgat atttgtgaaa atattaaaaa aaaatacttt ttttattaaa 30660
tgacgtcgct tcgcgaattt agaaaattat gctgtgatat atatcacgca tcaggatata 30720
aagaaaaatc taaattaatt agagacttta taacagatag ggatgataaa tatttgatca 30780
ttaagctatt gcttcccgga ttagacgata gaatttataa catgaacgat aaacaaatta 30840
taaaattata tagtataata tttaaacaat ctcaggaaga tatgctacaa gatttaggat 30900
acggatatat aggagacact attaggactt tcttcaaaga gaacacagaa atccgtccac 30960
gagataaaag cattttaact ttagaagaag tggatagttt tttaactacg ttatcatccg 31020
taactaaaga atcgcatcaa ataaaattat tgactgatat cgcatccgtt tgtacatgta 31080
atgatttaaa atgtgtagtc atgcttattg ataaagatct aaaaattaaa gcgggccctc 31140
ggtacgtact taacgctatt agtcctcatg cctatgatgt gtttagaaaa tctaataact 31200
tgaaagagat aatagaaaat gcatctaaac aaaatctaga ctctatatct atttctgtta 31260
tgactccaat taatcccatg ttagcggaat cgtgtgattc tgtcaataag gcgtttaaaa 31320
aatttccatc aggaatgttt gcggaagtca aatacgatgg tgaaagagta caagttcata 31380
aaaataataa cgagtttgcc ttctttagta gaaacatgaa accagtactc tctcataaag 31440
tggattatct caaagaatac ataccgaaag catttaaaaa agctacgtct atcgtattgg 31500
attctgaaat tgttcttgta gacgaacata atgtaccgct cccgtttgga agtttaggta 31560
tacacaaaaa gaaagaatat aaaaactcta acatgtgttt gttcgtgttt gactgtttgt 31620
actttgatgg attcgatatg acggacattc cattgtacga acgaagatct tttctcaaag 31680
atgttatggt tgaaataccc aatagaatag tattctcaga gttgacgaat attagtaacg 31740
agtctcagtt aactgacgta ttggatgatg cactaacgag aaaattagaa ggattggtct 31800
taaaagatat taatggagta tacgaaccgg gaaagagaag atggttaaaa ataaagcgag 31860
actatttgaa cgagggttcc atggcagatt ctgccgattt agtagtacta ggtgcttact 31920
atggtaaagg agcaaagggt ggtatcatgg cagtctttct aatgggttgt tacgacgatg 31980
aatccggtaa atggaagacg gttaccaagt gttcaggaca cgatgataat acgttaaggg 32040
agttgcaaga ccaattaaag atgattaaaa ttaacaagga tcccaaaaaa attccagagt 32100
ggttagtagt taataaaatc tatattcccg attttgtagt agaggatcca aaacaatctc 32160
agatatggga aatttcagga gcagagttta catcttccaa gtcccatacc gcaaatggaa 32220
tatccattag atttcctaga tttactagga taagagagga taaaacgtgg aaagaatcta 32280
ctcatctaaa cgatttagta aacttgacta aatcttaata gttacataca aattaaaata 32340
acactattta gttggtggtc gccatggatg gtgttattgt atactgtcta aacgcgttag 32400
taaaacatgg cgaggaaata aatcatataa aaaatgattt catgattaaa ccatgttgtg 32460
aaaaagtcaa gaacgttcac attggcggac aatctaaaaa caatacagtg attgcagatt 32520
tgccatatat ggataatgcg gtatccgatg tatgcaattc actgtataaa aagaatgtat 32580
caagaatatc cagatttgct aatttgataa agatagatga cgatgacaag actcctactg 32640
gtgtatataa ttattttaaa cctaaagatg ccattcctgt tattatatcc ataggaaagg 32700
atagagatgt ttgtgaacta ttaatctcat ctgataaagc gtgtgcgtgt atagagttaa 32760
attcatataa agtagccatt cttcccatgg atgtttcctt ttttaccaaa ggaaatgcat 32820
cattgattat tctcctgttt gatttctcta tcgatgcggc acctctctta agaagtgtaa 32880
ccgataataa tgttattata tctagacacc agcgtctaca tgacgagctt ccgagttcca 32940
attggttcaa gttttacata agtataaagt ccgactattg ttctatatta tatatggttg 33000
ttgatggatc tgtgatgcat gcaatagctg ataatagaac ttacgcaaat attagcaaaa 33060
atatattaga caatactaca attaacgatg agtgtagatg ctgttatttt gaaccacaga 33120
ttaggattct tgatagagat gagatgctca atggatcatc gtgtgatatg aacagacatt 33180
gtattatgat gaatttacct gatgtaggcg aatttggatc tagtatgttg gggaaatatg 33240
aacctgacat gattaagatt gctctttcgg tggctggtat ttggaaagtt ttataggtag 33300
ttgatagaac aaaatacata attttgtaaa aataaatcac tttttatact aatatgacac 33360
gattaccaat acttttgtta ctaatatcat tagtatacgc tacacctttt cctcagacat 33420
ctaaaaaaat aggtgatgat gcaactttat catgtaatcg aaataataca aatgactacg 33480
ttgttatgag tgcttggtat aaggagccca attccattat tcttttagct gctaaaagcg 33540
acgtcttgta ttttgataat tataccaagg ataaaatatc ttacgactct ccatacgatg 33600
atctagttac aactatcaca attaaatcat tgactgctag agatgccggt acttatgtat 33660
gtgcattctt tatgacatcg cctacaaatg acactgataa agtagattat gaagaatact 33720
ccacagagtt gattgtaaat acagatagtg aatcgactat agacataata ctatctggat 33780
ctacacattc accggaaact agttctgaga aacctgatta tatagataat tctaattgct 33840
cgtcggtatt cgaaatcgcg actccggaac caattactga taatgtagaa gatcatacag 33900
acaccgtcac atacactagt gatagcatta atacagtaag tgcatcatct ggagaatcca 33960
caacagacga gactccggaa ccaattactg ataaagaaga agatcataca gttacagaca 34020
ctgtctcata cactacagta agtacatcat ctggaattgt cactactaaa tcaaccaccg 34080
atgatgcgga tctttatgat acgtacaatg ataatgatac agtaccatca actactgtag 34140
gcggtagtac aacctctatt agcaattata aaaccaagga ctttgtagaa atatttggta 34200
ttaccgcatt aattatattg tcggccgtgg caatattctg tattacatat tatatatata 34260
ataaacgttc acgtaaatac aaaacagaga acaaagtcta gatttttgac ttacataaat 34320
gtctgggata gtaaaatcta tcatattgag cgggccatct ggtttaggaa agacagccat 34380
agccaaaaga ctatgggaat atatttggat ttgtggtgtc ccataccact agatttcctc 34440
gtcctatgga acgagaaggt gtcgattacc attacgttaa cagagaggcc atctggaagg 34500
gaatagccgc cggaacatac tgagttttta ggaaatattt acggaacttc taaaactgct 34560
gtgaatacag cggctattaa taatcgtatt tgtgtgatgg atctaaacat cgacggtgtt 34620
agaagtttta aaaatactta cctaatgcct tactcggtgt atataagacc tacctctctt 34680
aaaatggttg agaccaagct tcgttgtaga aacactgaag cggatgatga gattcatcgt 34740
cgtgtgatgt tggcaaaaac tgacatggat gaggcaggtg aagccggtct attcgacact 34800
attatcattg aagatgatgt gaatttagca tatagtaagt taattcagat actacaggac 34860
cgtattagaa tgtattttaa cactaattag agacttaaga cttaaaactt gataattaat 34920
aatataactc gtttttatat gtggctattt caacgtctaa tgtattagtt aaatattaaa 34980
acttaccacg taaaacttaa aatttaaaat gatatttcat tgacagatag atcacacatt 35040
atgaactttc aaggacttgt gttaactgac aattgcaaaa atcaatgggt cgttggacca 35100
ttaataggaa aaggtggatt tggtagtatt tatactacta atgacaataa ttatgtagta 35160
aaaatagagc ccaaagctaa cggatcatta tttaccgaac aggcatttta tactagagta 35220
cttaaaccat ccgttatcga agaatggaaa aaatctcaca atataaagca cgtaggtctt 35280
atcacgtgca aggcatttgg tctatacaaa tccattaatg tggaatatcg attcttggta 35340
attaatagat taggtgcaga tctagatgcg gtgatcagag ccaataataa tagattacca 35400
aaaaggtcgg tgatgttgat cggaatcgaa atcttaaata ccatacaatt tatgcacgag 35460
caaggatatt ctcacggaga tattaaagcg agtaatatag tcttggatca aatagataag 35520
aataaattat atctagtgga ttacggattg gtttctaaat tcatgtctaa tggcgaacat 35580
gttccattta taagaaatcc aaataaaatg gataacggta ctctagaatt tacacctata 35640
gattcgcata aaggatacgt tgtatctaga cgtggagatc tagaaacact tggatattgt 35700
atgattagat ggttgggagg tatcttgcca tggactaaga tatctgaaac aaagaattgt 35760
gcattagtaa gtgccacaaa acagaaatat gttaacaata ctgcgacttt gttaatgacc 35820
agtttgcaat atgcacctag agaattgctg caatatatta ccatggtaaa ctctttgaca 35880
tattttgagg aacccaatta cgacaagttt cggcacatat taatgcaggg tgtatattat 35940
taagtgtggt gtttggttga tgtaaaattt ttgtcgataa aaattaaaaa ataacttaat 36000
ttattattga tctcgtgtgt acaaccgaaa tcatggcgat gttttacgca cacgctctcg 36060
gtgggtacga cgagaatctt catgcctttc ctggaatatc atcgactgtt gccaatgatg 36120
tcagtttata ataacaagta tgacattgta aaagacaaat atatgtggtg ttacagtcag 36180
gtgaacaaga gatatattgg agcactgctg cctatgtttg agtgcaatga atatctacaa 36240
attggagatc cgatccatga tcaagaagga aatcacatat cgccacaaaa actactatgc 36300
tctaagcgga atcgggtacg agagtctaga cttgtgtttg gaaggagtag ggattcatca 36360
tcacgtactt gaaacagaaa acgctgtata tggaaaagtt caacatgatt attctactat 36420
caaagagaag gccaaagaaa tgaatgcact cagttcagga cctatcatcg attaccacgt 36480
ctggatagga gattgtatct gtcaagttac tgctgtggac gtacatggaa aggaaattat 36540
gagaatgaga ttcaaaaagg gtgcggtgct tccgatccca aatctggtaa aagttaaact 36600
tggggagaat gatacagaaa atctttcttc tactatatcg gcggcaccat cgaggtaacc 36660
acctctctgg aagacagtgt gaatcatgta ctcatgaaac gtttggaatc tatacgccat 36720
atgtggtctg ttgtatatga tcattttgat attgtgaatg gtaaagaatg ctgttatgtg 36780
catacgcatt tgtctaatca aaatcttata ccgagtactg taaaaacaaa tttgtacatg 36840
aagactatgg gatcatgcat tcaaatgagt atcttagcga actgaaggaa tcaggtggat 36900
ggagtcccag accagaaatg caggaatttg aatatccaga tggagtggaa gacactgaat 36960
caattgagag attggtagag gagttcttca atagatcaga acttcaggct ggtaaatcta 37020
ttaatgttaa acatacatct gtttcagcta agcaactaag aacacgtata ctctcatctt 37080
ttgccaacac agagggtgga tatttgttca ttggagttga taataataca cacaaagtat 37140
ttggattcac ggtgggttac gactacctca gactgataga gaatgatata gaaaagcata 37200
tcaaaagact ttgtgttgtg tatttctgtg agaagaaaga ggacatcaag tacacgtgtc 37260
gattcatcaa ggtatataaa cctggggatg aggctacctc gacatacgtg tgcgctatca 37320
aagtggaaag atgctgttgt gctgtgtttg cagattggcc agaatcatgg tatcaagaag 37380
tattctccag atgaataggt gtcacatata aaattttaat taatgtaact atagagaaca 37440
aataataggt tgtaatatca tatagacaat aactaacaat taattagtaa ctgttatctc 37500
tttttaacta actaactata cctattaata catcgtaatt atagttctta acatctatta 37560
atcattgatt cgcttcttta attttttata aaccaacatt gttaattgaa aagggataac 37620
atgttacaga atataaatta tatatggatt ttttttaaaa aggaaatact tgactggagt 37680
gtatatttat ctcttcatta tatagcacgc gtgttttcca atttttccac atcccatata 37740
atacaggatt ataatctcgt tcgaacatac gagaaagtgg ataaaacaat agttgatttt 37800
ttatctaggt tgccaaattt attccatatt ttagaatatg gggaaaatat tctacatatt 37860
tattctatgg atgatgctaa tacgaatatt ataatttttt ttctagatag agtattaaat 37920
attaataaga acgggtcatt tatacacaat ctcaggttat catcatccat taatataaaa 37980
gaatatgtat atcaattagt taataatgat catccagata ataggataag actaatgctt 38040
gaaaatggac gtagaacaag acattttttg tcctatatat cagatacagt taatatctat 38100
atatgtattt tatatagatg ccgaagacag ttacggttgt acattattac atagatgtat 38160
atatcactat aagaaatcag aatcagaatc agaatcatac aatgaattaa ttaagatatt 38220
gttaaataat ggatcagatg tagataaaaa agatacgtac ggaaacacac cttttatcct 38280
attatgtaaa cacgatatca acaacgtgga attgtttgag atatgtttag agaatgctaa 38340
tatagactct gtagacttta atagatatac acctcttcat tatgtctcat gtcgtaataa 38400
atatgatttt gtaaagttat taatttctaa aggagcaaat gttaatgcgc gtaataaatt 38460
cggaactact ccattttatt gtggaattat acacggtatc tcgcttataa aactatattt 38520
ggaatcagac acagagttag aaatagataa tgaacatata gttcgtcatt taataatttt 38580
tgatgctgtt gaatctttag attatctatt atccagagga gttattgata ttaactatcg 38640
tactatttac gacgctgtca gttataatgc gtataatacg ttggtctatc tattaaacag 38700
aaatggtgat tttgagacga ttactactag tggatgtaca tgtatttcgg aagcagtcgc 38760
aaacaacaac aaaataataa tggaagtact attgtctaaa cgaccatctt tgaaaattat 38820
gatacagtct atgatagcaa ttactaaaca taaacagcat aatgcagatt tattgaaaat 38880
gtgtataaaa tatactgcgt gtatgaccga ttatgatact cttatagatg tacaatcact 38940
acagcaatat aaatggtata ttttaagatg tttcgatgaa atagatatca tgaagagatg 39000
ttatataaaa aataaaactg tattccaatt agttttttgt atcaaagaca ttaatacttt 39060
aatgagatac ggtaaacatc cttctttcgt gaagtgcact agtctcgacg tatacggaag 39120
tcgtgtacgt aatatcatag catctattag atatcgtcag agattaatta gtctattatc 39180
caagaagctg gatcctggag ataaatggtc gtgttttcct aacgaaataa aatataacga 39240
taacgaactg tccacatatc taaaaatctt ataaacacta ttaaaatata aaatcacact 39300
acatcattgt ttccttttag tgctcgacag tgtatactat ttttaacgct cataaataaa 39360
aatgaaaacg atttccgttg ttacgttgtt atgcgtacta cctgctgttg tttattcaac 39420
atgtactgta cccactatga ataacgctaa attaacgtct accgaaacat cgtttaataa 39480
taaccagaaa gttacgttta catgtgatca gggatatcat tcttcggatc caaatgctgt 39540
ctgcgaaaca gataaatgga aatacgaaaa tccatgcaaa aaaatgtgca cagtttctga 39600
ttacatctct gaactatata ataaaccgct atacgaagtg aattccacca tgacactaag 39660
ttgcaacggc gaaacaaaat attttcgttg cgaagaaaaa aatggaaata cttcttggaa 39720
tgatactgtt acgtgtccta atgcggaatg tcaacctctt caattagaac acggatcgtg 39780
tcaaccagtt aaagaaaaat actcatttgg ggaatatata actatcaact gtgatgttgg 39840
atatgaggtt attggtgctt cgtacataag ttgtacagct aattcttgga atgttattcc 39900
atcatgtcaa caaaaatgtg atataccgtc tctatctaat ggattaattt ccggatctac 39960
attttctatc ggtggcgtta tacatcttag ttgtaaaagt ggttttatac taacgggatc 40020
tccatcatcc acatgtatcg acggtaaatg gaatcccata ctcccaacat gtgtacgatc 40080
taacgaaaaa tttgatccag tggatgatgg tcccgacgat gagacagatt tgagcaaact 40140
ctcgaaagac gttgtacaat atgaacaaga aatagaatcg ttagaagcaa cttatcatat 40200
aatcatagtg gcgttaacaa ttatgggcgt catattttta atctccgtta tagtattagt 40260
ttgttcctgt gacaaaaata atgaccaata taagttccat aaattgctac cgtgaatata 40320
aatccgttaa aataatgaat aattaataat taataattta ataacaaaca agtatcaaaa 40380
gattaaagac ttatagctag aatcaattga gatgtcttct tcagtggatg ttgatatcta 40440
cgatgccgtt agagcatttt tactcaggca ctattataac aagagattta ttgtgtatgg 40500
aagaagtaac gccatattac ataatatata caggctattt acaagatgcg ccgttatacc 40560
gttcgatgat atagtacgta ctatgccaaa tgaatcacgt gttaaacaat gggtgatgga 40620
tacacttaat ggtataatga tgaatgaacg cgatgtttct gtaagcgttg gcaccggaat 40680
actattcatg gaaatgtttt tcgattacaa taaaaatagt atcaacaatc aactaatgta 40740
tgatataatt aatagcgtat ctataattct agctaatgag agatatagaa gcgcttttaa 40800
cgacgatggt atatacatcc gtagaaatat gattaacaag ttgtacggat acgcatctct 40860
aactactatt ggcacgatcg ctggaggtgt ttgttattat ctgttgatgc atctagttag 40920
tttgtataaa taattatttc aatatactag ttaaaatttt aagattttaa atgtataaaa 40980
aactaataac gtttttattt gtaataggtg cattagcatc ctattcgaat aatgagtaca 41040
ctccgtttaa taaactgagt gtaaaactct atatagatgg agtagataat atagaaaatt 41100
catatactga tgataataat gaattggtgt taaattttaa agagtacaca atttctatta 41160
ttacagagtc atgcgacgtc ggatttgatt ccatagatat agatgttata aacgactata 41220
aaattattga tatgtctact attcaacgca gaggtcacac gtgtagaata tctaccaaat 41280
tatcatgcca ttatgataag tacccttata ttcacaaata tgatggtgat gagcgacaat 41340
attctattac tgcagaggga aaatgctata aaggaataaa atatgaaata agtatgatca 41400
acgatgatac tctattgaga aaacatactc ttaaaattgg atctacttat atatttgatc 41460
gtcatggaca tagtaataca tattattcaa aatatgattt ttaaaaattt aaaatatatt 41520
atcacttcag tgacagtagt caaataacaa acaacaccat gagatatatt ataattctcg 41580
cagttttgtt cattaatagt atacacgcta aaataactag ttataagttt gaatccgtca 41640
attttgattc caaaattgaa tggactgggg atggtctata caatatatcc cttaaaaatt 41700
atggcatcaa gacgtggcaa acaatgtata caaatgtacc agaaggaaca tacgacatat 41760
ccgcatttcc aaagaatgat ttcgtatctt tctgggttaa atttgaacaa ggcgattata 41820
aagtggaaga gtattgtacg ggaccaccga ctgtaacatt aactgaatac gacgaccatc 41880
cgtatgctac tagaggtagc aaaaagattc ctatttacaa acgcggtgac atgtgtgata 41940
tctacttgtt gtatacggct aacttcacat tcggagattc taaagaacca gtaccatatg 42000
atatcgatga ctacgattgc acgtctacag gttgcagcat agactttgtc acaacagaaa 42060
aagtgtgcgt gacagcacag ggagccacag aagggtttct cgaaaaaatt actccatgga 42120
gttcgaaagt atgtctgaca cctaaaaaga gtgtatatac atgcgcaatt agatccaaag 42180
aagatgttcc caatttcaag gacaaaatgg ccagagttat caagagaaaa tttaactaaa 42240
tttctcggta gcacatcaaa tgatgttacc acttttctta gcatgcttaa cttgactaaa 42300
tattcataac taatttttat taatgataca aaaacgaaat aaaactgcat attatacact 42360
ggttaacgcc cttataggct ctaaccattt tcaagatgag gtccctgatt atagtccttc 42420
tgttcccctc tatcatctac tccatgtcta ttagacgatg tgagaagact gaagaggaaa 42480
catggggatt gaaaataggg ttgtgtataa ttgccaaaga tttctatccc gaaagaactg 42540
attgcagtgt tcatctccca actgcaagtg aaggcaatgg attcagggat atacgaaaca 42600
ccgataaatt ataaaaaaag caatgtgtcc gctgtttccg ttaataatac tattttcgta 42660
actggcggat tattcataaa taactctaat agcacgatcg tggttaacaa tatggaaaaa 42720
cttgacattt ataaagacaa acaatggtcg attatagaaa tgcctatggc tagggtatat 42780
cacggcatcg actcgacatt tggaatgtta tattttgccg gaggtctatc cgttaccgaa 42840
caatatggta atttagagaa aaacaacgag atatcttgtt acaatcctag aacgaataag 42900
tggtttgata tttcatatac tatttataag atatccatat catcattgtg taaactaaat 42960
aacgtcttct atgtatttag taaggacatt ggatatgtgg aaaagtatga tggtctcccc 43020
gctataaagg cattatcaac ttctccttat tgattgaaaa tgaaaatata aatagttttt 43080
atgtatagca gtattaccct atagttttat tgcttactac taacatggat acagatacag 43140
atgttacaaa tgtagaagat atcatgaatg aaatagatag agagaaagaa gaaatactaa 43200
aaaatgtaga aattgaaaat aataaaaaca ttaacaagaa tcatcccaat gaatatatta 43260
gagaagcact cgttattaat acaagtagta atagtgattc cattgataaa gaagttatag 43320
aatgtatcag tcacgatgta ggaatataga tcatatctac taatttttat aatcaataca 43380
aaacataaaa aacaactcgt tattacatag caggcatgga atccttcaag tattgttttg 43440
ataacgatgg caagaaatgg attatcggaa atactttata ttctggtaat tcaatactct 43500
ataaggtcag aaaaaatttc actagttcgt tctacaatta cgtaatgaag atagatcaca 43560
aatcacacaa gccattgttg tctgaaatac gattctatat atctgtattg gatcctttga 43620
ctatcgacaa ctggacacgg gaacgtggta taaagtattt ggctattcca gatctgtatg 43680
gaattggaga aaccgatgat tatatgttct tcgttataaa gaatttggga agagtattcg 43740
ccccaaagga tactgaatca gtcttcgaag catgcgtcac tatgataaac acgttagagt 43800
ttatacactc tcgaggattt acccatggaa aaatagaacc gaggaatata ctgattagaa 43860
ataaacgtct ttcactaatt gactattcta gaactaacaa actatacaag agtggaaact 43920
cacatataga ttacaacgag gacatgataa cttcaggaaa tatcaattat atgtgtgtag 43980
acaatcatct tggagcaaca gtttcaaaac gaggagattt agaaatgttg ggatattgca 44040
tgatagaatg gttcggtggc aaacttccat ggaaaaacga aagtagtata aaagtaataa 44100
aacaaaaaaa agaatataaa aaatttatag ctactttctt tgaggactgt tttcctgaag 44160
gaaatgaacc tctggaatta gttagatata tagaattagt atacacgtta gattattctc 44220
aaactcctaa ttatgacaga ctacgtagac tgtttataca agattgaaat attctttttt 44280
tatagagtgt ggtagtgtta cggatatcta atattaatat tagactatct ctatcgcgct 44340
acacgaccaa tatcgattac tatggatatc ttctatgaaa ggagagaatg tattcatttc 44400
tccagcgtca atctcgtcag tattgacaat actgtattat ggagctaatg gatccactgc 44460
tgaacagcta tcaaaatatg tagaaaagga ggagaacacg gataaggtta gcgctcagaa 44520
tatctcattc aaatccatga ataaagtata tgggcgatat tctgccgtgt ttaaagattc 44580
ctttttgaga aaaattggcg ataagtttca aactgttgac ttcactgatt gtcgcactat 44640
agatgcaatc aacaagtgtg tagatatctt tactgagggg aaaatcaatc cactattgga 44700
tgaacaattg tctcctagca attagtgccg tatactttaa agcaaaatgg ttgacgccat 44760
tcgaaaagga atttaccagt gattatccct tttacgtatc accaacggaa atggtagacg 44820
taagtatgat gtctatgtac ggcgagctat ttaatcacgc atctgtaaaa gaatcattcg 44880
gtaacttttc aatcatagaa ctgccatatg ttggagatac tagtatgatg gtcattcttc 44940
cagacaagat tgatggatta gaatccatag aacaaaatct aacagataca aattttaaga 45000
aatggtgtaa ctctctggaa gctacgttta tcgatgttca cattcccaag tttaaggtaa 45060
caggctcgta taatctggtg gatactctag taaagtcagg actgacagag gtgttcggtt 45120
caactggaga ttatagcaat atgtgtaatt tagatgtgag tgtcgacgct atgatccaca 45180
aaacgtatat agatgtcaat gaagagtata cagaagcagc tgcagcaact tgtgcactgg 45240
tgtcagactg tgcatcaaca attacaaatg agttctgtgt agatcatccg ttcatctatg 45300
tgattaggca tgttgatgga aaaatttttt tcgttggtag atattgctct ccgacaacta 45360
attgttaacc atttttttta aaaaaataga aaaaacatgt ggtattagtg caggtcgtta 45420
ttcttccaat tgcaattggt aagatgacgg ccaactttag tacccacgtc ttttcaccac 45480
agcactgtgg atgtgacaga ctgaccagta ttgatgacgt caaacaatgt ttgactgaat 45540
atatttattg gtcgtcctat gcataccgca acaggcaatg cgctggacaa ttgtattcca 45600
cactcctctc ttttagagat gatgcggaat tagtgttcat cgacattcgc gagctggtaa 45660
aaaatatgcc gtgggatgat gtcaaagatt gtgtagaaat catccgttgt tatataccgg 45720
atgagcaaaa aaccatcatc ggactttgtg catatgctgc tacttactgg ggaggtgaag 45780
accatcccac tagtaacagt ctgaacgcat tgtttgtgat gcttgagatg ctaaattacg 45840
tggattataa catcatattc cggcgtatga attgatgagt tgtacatctt gacattttct 45900
tctttcttct cttctccctt tcccagaaac aaactttttt tacccactat aaaataaaat 45960
gagtatacta cctgttatat ttctttctat atttttttat tcttcattcg ttcagacttt 46020
taacgcgcct gaatgtatcg acaaagggca atattttgca tcattcatgg agttagaaaa 46080
cgagccagta atcttaccat gtcctcaaat aaatacgcta tcatccggat ataatatatt 46140
agatatttta tgggaaaaac gaggagcgga taatgataga attataccga tagataatgg 46200
tagcaatatg ctaattctga acccgacaca atcagactct ggtatttata tatgcattac 46260
cacgaacgaa acctactgtg acatgatgtc gttaaatttg acaatcgtgt ctgtctcaga 46320
atcaaatata gatcttatct cgtatccaca aatagtaaat gagagatcta ctggcgaaat 46380
ggtatgtccc aatattaatg catttattgc tagtaacgta aacgcagata ttatatggag 46440
cgggcatcga cgccttagaa ataagagact taaacaacgg acacctggaa ttattaccat 46500
agaagatgtt agaaaaaatg atgctggtta ttatacatgt gttttagaat atatatacgg 46560
tggcaaaaca tataacgtaa ccagaattgt aaaattagag gtacgggata aaataatacc 46620
ttctactatg caattaccag aaggtgttgt aacttcaata ggtagtaatt tgactattgc 46680
gtgtagagta tcgttgagac ctcccacaac ggatgcagac gtcttttgga taagtaatgg 46740
tatgtattac gaagaagatg atggggacgg agacggtaga ataagtgtag caaataaaat 46800
ctatatgacc gataagagac gtgttattac atcccggtta aacattaatc ctgtcaagga 46860
agaagatgct acaacgttta cgtgtatggc gtttactatt cctagcatca gcaaaacagt 46920
tactgttagt ataacgtgaa tgtatgttgt tacatttcca tgtcaattga gtttataaga 46980
atttttatac attatcttcc aacaaacaat tgacgaacgt attgctatga ttaactccca 47040
cgatactatg catattatta atcattaact tgcagactat acctagtgct attttgacat 47100
actcatgttc ttgtgtaatt gcggtatcta tattattaaa gtacgtaaat ctagctatag 47160
ttttattatt taattttaga taatataccg tctccttatt tttaaaaatt gccacatcct 47220
ttattaaatc atgaatggga atttctatgt catcgttaat atattgtgaa caacaagagc 47280
agatatctat aggaaagggt ggaatgcgat acattgatct atgtagtttt aaaacacacg 47340
cgaactttga agaatttata taaatcattc catcgataca tccttctatg ttgacatgta 47400
tatatccagg aattctttta ttaatgtcag gaaatgtata aactaaaaca ttgcccgaaa 47460
gcggtgcctc tatctgcgtt atatccgttc ttaacttaca aaatgtaacc aatacctttg 47520
catgacttgt tttgttcggc aacgttagtt taaacttgac gaatggatta attacaatag 47580
catgatccgc gcatctatta agttttttta ctttaacgcc cttgtatgtt tttacagaga 47640
ctttatctaa atttctagtg cttgtatgtg ttataaatat aacgggatat agaactgaat 47700
cacctacctt agatacccaa ttacatttta tcagatccag ataataaaca aattttgtcg 47760
ccctaactaa ttctatattg ttatatattt tacaattggt tatgatatca tgtaataact 47820
tggagtctaa cgcgcatcgt cgtacgttta tacaattgtg atttagtgta gtatatctac 47880
acatgtattt ttccgcacta tagtattctg gactagtgat aaaactatcg ttatatctgt 47940
cttcaatgaa ctcatcgaga tattgctctc tgtcatattc atacacctgc ataaactttc 48000
tagacatctt acaatccgtg ttattttagg atcatattta catatttacg ggtatatcaa 48060
agatgttaga ttagttaatg ggaatcgtct ataataatga atattaaaca attatatgag 48120
gacttttacc acaaagcatc ataaaaatga gtcgtcgtct gatttatgtt ttaaatatca 48180
accgcgaatc aactcataaa atacaagaga atgaaatata tacatatttt agtcattgca 48240
atatagacca tacttctaca gaacttgatt ttgtagttaa aaactatgat ctaaacagac 48300
gacaacctgt aactgggtat actgcactac actgctattt gtataataat tactttacaa 48360
acgatgtact gaagatatta ttaaatcatg gagtggatgt aacgatgaaa accagtagcg 48420
gacgtatgcc tgtttatata ttgcttacta gatgttgtaa tatttcacat gatgtagtga 48480
tagatatgat agacaaagat aaaaaccact tatcgcatag agactattcc aacctactac 48540
tagagtatat aaaatctcgt tacatgttat tgaaggaaga ggatatcgat gagaacatag 48600
tatccacttt attagataag ggaatcgatc ctaactttaa acaagacgga tatacagcgt 48660
tacattatta ttatttgtgt ctcgcacacg tttataaacc aggtgagtgt agaaaaccga 48720
taacgataaa aaaggccaag cgaattattt ctttgtttat acaacatgga gctaatctaa 48780
acgcgttaga taattgtggt aatacaccat tccatttgta tcttagtatt gaaatgtgta 48840
ataatattca tatgactaaa atgctgttga cttttaatcc gaatttcaaa atatgtaata 48900
atcatggatt aacgcctata ctatgttata taacttccga ctacatacaa cacgatattc 48960
ttgttatgtt aatacatcac tatgaaacaa atgttggaga aatgccgata gatgagcgtc 49020
gtataatcgt attcgagttt atcaaaacat attctacacg tccggcagat tcgataactt 49080
atttgatgaa taggtttaaa aatatagata tttatacccg ctatgaagga aagacattat 49140
tacacgtagc atgtgaatat aataatacac acgtaataga ttatcttata cgtatcaacg 49200
gagatataaa tgcgttaacc gacaataaca aacacgctac acaactcatt atagataaca 49260
aagaaaattc cccatatacc attaattgtt tactgtatat acttagatat attgtagata 49320
agaatgtgat aagatcgttg gtggatcaac ttccatctct acctatcttc gatataaaat 49380
catttgagaa attcatatcc tactgtatac ttttagatga cacattttac aatagacacg 49440
ttaggaatcg caattctaaa acgtatcgat acgcattttc aaaatacatg tcgtttgata 49500
aatacgatgg tataataact aaatgtcata aagaaacaat attgctcaaa ctatccactg 49560
ttctagacac tacactatat gcagttttaa gatgccataa ttcgaaaaag ttaagaagat 49620
acctcaacga gttaaaaaaa tataataacg ataagtcctt taaaatatat tctaatatta 49680
tgaatgagag ataccttaat gtatattata aagatatgta cgtgtcaaag gtatatgata 49740
aactatttcc tgttttcaca gataaaaatt gtctactaac attactacct tcagaaatta 49800
tatacgaaat attatacatg ctgacaatta acgatcttta taatatatcg tatccaccta 49860
ccaaagtata gttgtatttt tctcatgcga tgtgtgtaaa aaaactgata ttatataaat 49920
attttagtgc cgtataatga agatgacgat gaaaatgatg gtacatatat atttcgtatc 49980
attattgtta ttgctattcc acagttacgc catagacatc gaaaatgaaa tcacagaatt 50040
cttcaataaa atgagagata ctctaccagc taaagactct aaatggttga atccagcatg 50100
tatgttcgga ggcacaatga atgatatagc cgctctagga gagccattca gcgcaaagtg 50160
tcctcctatt gaagacagtc ttttatcgca cagatataaa gactatgtgg ttaaatggga 50220
gaggctagaa aaaaatagac ggcgacaggt ttctaataaa cgtgttaaac atggtgattt 50280
atggatagcc aactatacat ctaaattcag taaccgtagg tatttgtgta ccgtaactac 50340
aaagaatggt gactgtgttc agggtatagt tagatctcat attaaaaaac ctccttcatg 50400
cattccaaaa acatatgaac taggtactca tgataagtat ggcatagact tatactgtgg 50460
aattctttac gcaaaacatt ataataatat aacttggtat aaagataata aggaaattaa 50520
tatcgacgat attaagtatt cacaaacggg aaagaaatta attattcata atccagagtt 50580
agaagatagt ggaagataca actgttacgt tcattacgac gacgttagaa tcaagatgta 50640
aaatacttac ggttataccg tcgcaagacc acaggtttaa actaatacta gatccaaaaa 50700
tcaacgtaac gataggagaa cctgccaata taacatgcac tgctgtgtca acgtcattat 50760
tgattgacga tgtactgatt gaatgggaaa atccatccgg atggcttata ggattcgatt 50820
ttgatgtata ctctgtttta actagtagag gcggtatcac cgaggcgacc ttgtactttg 50880
aaaatgttac tgaagaatat ataggtaata catataaatg tcgtggacac aactattatt 50940
ttgaaaaaac ccttacaact acagtagtat tggagtaaat acacaatgca tttttatata 51000
cattactgaa taattattat tattatttat atcgtatttg tgctataacg cgactatcta 51060
ggtatttgta tctcaccgat agagaacata taaatgtaga ctctattaaa cagttgtgta 51120
aaatatcaga tcctaataga tgtggatgta cggctttaga aatgagttca ttaaaatatg 51180
tgatatcaac ggaacatatt tatataatta tactattgct gttagtataa ttattgattc 51240
cacggaagaa ctaccaacag ttactccaat tacaacaaca tataattata ctatcgatga 51300
tagcactact gaagaactac aagtgactcc tcatatggat ctccatcgat gatacatgta 51360
ttaaaatact ttccgaataa gtcttttaaa tattgtatta attatgaaaa actatgctat 51420
gcgagtatga tacgatacta gattttatct ctagcgagag atgtcgttag aatcatttat 51480
caacgaatat cgataacatg tgtcatttat acgttaaagt ctgtccgtct tctctattgt 51540
ttagactgtt tgtagaatgc tgtgatataa acaaactagt agacacaaat atttaactca 51600
tgatgaagtt gagaatgata tgctttagct aatataaaaa tatattaatc cactatatat 51660
tctagacttg atttaaaacc gataaactac tactacgtac tgtataagtt aggagcagac 51720
cctaattatg tagatgatag aggtaatact tctgcatcta tatgtccact tatgagaaaa 51780
cgtcatttaa taagatgcat cgtgaaaaga aatttattaa agagttggta aaatatgaaa 51840
ccgaaagtaa ataatatagg aaatacacct ctacataact acgtatctca atatgatatc 51900
actctcattc ctcatccaca acccattaaa aaatggaaat taaagccctc tattagcata 51960
aacggctaca ggtctacctt tacaatggcc tttccttgtg cccagttcag accctgtcat 52020
tgccacgcta ctaaggactc cctgaatacc gtggccgacg tcagacattg tctgactgaa 52080
tacatcctgt gggtttctca tagatggacc catagagaaa gcgcagggtc tctctacagg 52140
cttctcatct ctttcagaac tgatgcaacg gagctctttg gtggtgagtt gaaggattca 52200
cttccgtgga gatcattaaa tgactccatg aaaaccgccg aagaacttcg tgcaatcatt 52260
ggactttgta ctcaatcagc tatcgtctct ggaagagtct tcaacgataa gtatatcgac 52320
atactactta tgctgcgaaa gattctgaac gagaacgact atctcaccct cttggatcat 52380
atccgcactg ctaaatacta aatctccttc atgctctctc actacacttt ttatcatctt 52440
atgaggaata attagcacca gaatagctat ggattgcaca tgtattctat gtcgtctact 52500
ggatgaagat gtgacgtaca aaaaaataaa actagaaatt gaaacgtgtc acaacttatc 52560
aaaacatata gatagacgag gaaacaatgc gctacattgt tacgtctcca ataaatgcga 52620
tacagacatt aagattgttc gactgttact ctctcgcgga gtcgagagac tttgtagaaa 52680
caacgaagga ttaactccgc taggagcata cagtaagcat agatacgtaa aatctcagat 52740
tgtgcatcta ctgatatcca gctattcgaa ttcctctaac gaactcaagt cgaatataaa 52800
tgatttcgac ttacgtctgc taaaatacct aattgtggat aaacggatac gtccgtccaa 52860
gaatacgaat tatgcaatca atggtctcgg attggtggat atatacgtaa cgacgcctaa 52920
tccgagacca gaagtattgc tatggcttct taaatcagaa tgttacagca ccggttacgt 52980
atttcgtacc tgtatgtaca acagtgatat gtgtaagaac tctcttcatt actatatatc 53040
gtctcataga gaatctctat ccaaggatgt aattaaatgt ttgatcgata acaatgtttc 53100
catccaatac tactggtctt gctcaaccat agatatagag attattaata aaggatgtgg 53160
acacgtgtag agtatacgac gtcagcccta tattagaggc gtattatcta aacaagcgat 53220
ttagagtaac cccatataat gtagacatgg aaatcgttaa tcttcttatt gagagacgtc 53280
atactcttgt cgacgtaatg cgtagtatta cttcgtacga ttccagagaa tataaccact 53340
acatcatcga taacattcta aagagattta gacaacagga tgaatccatc gtacaagcca 53400
tactgataaa ctacttacat tacggcgata tggtaagtat acctatcatt caatgcatgt 53460
tggataagac gacggacaac aactttgtta ataataatct cgtcgatgta aacgtcgtaa 53520
ggtttatcgt ggaaaatatg gacacgcggc tgtaaatcac atatctaaca atggccgtct 53580
atgtatgtac ggtctgatat tatcgagatt taataattgc gggtatcact gttatgaaga 53640
tgtatttgat atactaagca agtacatgga tgatatagat atgatcgata actctactat 53700
attacgcggt cgatgtcaat aatatacaat ttgcaaagcg gttattggaa tatggagcga 53760
gtgtcacgct cgataatcaa tacggccatc cagaaaagca gttaccaaag agaagctagt 53820
tgatttatta ctgagttacc atcccactct agagactatg attgacgcat ttaatagaga 53880
tatacgctat ctatatcctg aaccattatt cgcctgtatc agatacgcct taatcctaga 53940
tgatgatttt ccttctaaag taagtatgat atcgccggtc gtcataagga actaaagcgc 54000
tatagagcag acattaatag aatgaagaat gcctacatat caggcgtctc catgtttgat 54060
atattattta aacgaagcaa acgccacaga ttgagatacg caaagaacaa tgagaggatc 54120
gactccatta aataatttat catggagtga taatgtcctg tttccatggc atattacaaa 54180
atcgattccg tccaagatga taaaaacatt taccggcatc ataaacacgg agtttatttt 54240
atatgtctcg cataaacatt actaaaaaaa tatattgttc ggttttcttt cacatcttta 54300
attatgaaaa agtaaatcat tatgagatgg acgcatcgtt cgcgacagta tgtggtacat 54360
acctaacgta tttatggacg acggtaagaa tgaaggtcac gtttctgtca acaatgtcga 54420
cgcgatcgtg taacacgact cacaatagaa tctgtgaatg ctctcccgat catggatgca 54480
aggcatgtgt ttcccaaaca aaatgtggaa taggatacgg agtatccgga gacgtcatct 54540
gttctccgtg tggtctcgga acatattctc acaccgtctc ttccgcagat aaatgcgaac 54600
ccgtacccag aaataccttt aactatatcg atgtggaaat taacctgtat ccagttaacg 54660
acacatcgtg tactcggacg accactaccg gtctcagcga atccatctca acgtcggaac 54720
taactattac tatgaatcat aaagactgcg atcccgtctt cttaataagg tagcgacttc 54780
aggtttcttt acaggagaaa ggtgtgcact ctgaatttcg agattaaatg caataacaaa 54840
gattcttcct ccaaacagtt aacgaaagca aagaatgata ctatcatgcc gcattcggag 54900
acagtaactc tagcgtcgac atctatatac tatatagtaa taccaatact caagactacg 54960
aaactgatac aatctcttat catgtgggta atgtagccat atgcccggta gttgcgatat 55020
acataaactg atcactaatt ccaaacccac ccgcttttta tagtaagttt ttcacccata 55080
aatacaataa ttaatttctc gtaaaagtag aaaatatatt ctaatttatt gcacggtaag 55140
gaagtagaat cataaagaac agtactcaat caatagcaat catgaaacaa tatatcgtac 55200
tggcatgcat gtgcctgcca gtcttcagca atcatcctca tcgtgtacgg aagaagaaaa 55260
caaacatcat atgggaatcg atgttattat caaagtcaca aagcaagacc aaacaccgac 55320
cgatgataag atttgccaat ccgtaacgga aattacagag tccgagtcag atccagatcc 55380
cgaggtggaa tcagtcgagg atgtagatcc tcctaccact tattactcca tcatcggtgg 55440
aggtctgaga atgaactttg gattcaccaa atgtcctcag attaaatcca tctcagaatc 55500
cgctgatgga aagactgtga ggtgtctatc gacatcagat gtagcgaaga agagaaagac 55560
agcgacatca agacccatcc agtactcggg tctaacatct ctcataagaa agtgagttac 55620
gaagatatca tcggttcaac gatcgtcgat acaaaatgtg tcaagaatct agagtttagc 55680
gttcgtatcg gagacatgtg caaggaatca tctgaacttg aggtcaagta tgtcgacgga 55740
tcggcatctg aaggtgcaac cgatgatact tcactcatcg attcaacaaa actcaaagcg 55800
tgtgtctgaa tcgataactc tattcatctg aaattggatg agtagggtta atcgaacgat 55860
tcaggcacac cacgaattaa aaaagtgtac cggacactat attccggttt gcaaaacaaa 55920
aagttacctc tcgcgacttc ttctttttct gtctcaatag tgtgatacga ttatgacact 55980
attcctattt cctttcaggg tatcacaaaa atattaaacc tctttctgat ggtctcatac 56040
aaaaatattt ttattctctt tctctctttg atggtctcat aaaaaatatt tttattctct 56100
ttctctcttt gatggtctca taaaatattt ttattctctt tctctctttg atggtctcat 56160
aaaaaatatt tttattctct ttctctcttt gatggtctca taaaatattt ttattctctt 56220
tctctctttg atggtctcat aaaaaatatt tttattctct ttctctcttt gatggtctca 56280
taaaaaatat taaacctctt tctgatggtg tcactaaaat atttttattc tctttctctc 56340
ttcaatggag tcataaaata tttttattct ctttctctct tcgatggtct cacaaaaata 56400
ttaaacctct ttctgatggt gtcactaaaa tatttttatt ctctttctct cttcaatgga 56460
gtcataaaat atttttattc tctttctctc tttgatggtc tcacaaaaat atttttattc 56520
tctttctctc tttgatggtc tcacaaaaat atttttattc tctttctctc tttgatggtc 56580
tcacaaaaat atttttattc tctttctctc tttgatggtc tcataaaaaa agttttacaa 56640
aaatattttt attctctttc tctctttgat ggtctcataa aaaaagtttt acaaaaatat 56700
ttttattctc tttctctctt tgatggtctc ataaaaaaag ttttacaaaa atatttttat 56760
tctctttctc tctttgatgg tctcataaaa aatattaaac ctctttctga tggtgtcact 56820
aaaatatttt tattctcatt ctctcttcaa tggagtcata aaatattttt attctctttc 56880
tctcttcgat ggtctcacaa aaatattaaa cctctttctg atggtgtcac taaaatattt 56940
ttattctcat tctctcttca atggagtcat aaaatatttt tattctcttt ctctcttcga 57000
tggtctcaca aaaatattaa acctctttct gatggtgtca ctaaaatatt tttattctca 57060
ttctctcttc aatggagtca taaaatattt ttattctctt tctctctttg atggtctcat 57120
aaaaaaagtt ttacaaaaat atttttattc tctttctctc tttgatggtc tcataaaaaa 57180
tattaaacct ctttctgatg gtgtcactaa aatattttta ttctctttct ctcttcaatg 57240
gagtcataaa atatttttat tctctttctc tcttcgatgg tctcacaaaa atattaaacc 57300
tctttctgat ggtgtcacta aaatattttt attctcattc tctcttcaat ggagtcataa 57360
aatattttta ttctctttct ctctttgatg gtctcataaa aaaagtttta caaaaatatt 57420
tttattctct ttctctcttt gatggtctca taaaaaaagt tttacaaaaa tatttttatt 57480
ctctttctct ctttgatggt ctcataaaaa aagttttaca aaaatatttt tattctcttt 57540
ctctctttga tggtctcata aaaaaagttt tacaaaaata tttttattct ctttctctct 57600
ttgatggtct cataaaaaat attaaacctc tttctgatgg tgtcactaaa atatttttat 57660
tctcattctc tcttcaatgg agtcataaaa tatttttatt ctctttctct cttcgatggt 57720
ctcacaaaaa tattaaacct ctttctgatg gtgtcactaa aatattttta ttctcattct 57780
ctcttcaatg gagtcataaa atatttttat tctctttctc tctttgatgg tctcataaaa 57840
aaagttttac aaaaatattt ttattctctt tctctctttg atggtctcat aaaaaaagtt 57900
ttacaaaaat atttttattc tctttctctc tttgatggtc tcataaaaaa agttttacaa 57960
aaatattttt attctctttc tctctttgat ggtctcataa aaaaagtttt acaaaaatat 58020
ttttattctc tttctctctt tgatggtctc acaaaaatat taaacctctt tctgatggag 58080
tcgtaaaaaa gttttatctc tttctccttc gatggtctca caaaaatatt aaacctcttt 58140
ctgatggagt cgtaaaaaag ttttatctct ttctctcttc gatggtctca caaaaatatt 58200
aaacctcttt ctgatggagt cgtaaaaaag ttttatctct ttctctcttc gatggtctca 58260
ctaaaatatt ttttattctc tttctgatgc atcaactatt tcttaaacaa taacgtccaa 58320
caacatatac tcgtcgagct tatcaacatc ccctatgccc atctaggtta ccagacaatt 58380
gtatatcata aaataatgtt tataattttt acaaaaatat ttttattctc tttctctctt 58440
tgatggtctc ataaaaaaag ttttacaaaa atatttttat tctctttctc tctttgatgg 58500
tctcataaaa aatattaaac ctctttctga tggtgtcact aaaatatttt tattctcatt 58560
ctctcttcaa tggagtcata aaatattttt attctctttc tctcttcgat ggtctcacaa 58620
aaatattaaa cctctttctg atggtgtcac taaaatattt ttattctcat tctctcttca 58680
atggagtcat aaaatatttt tattctcttt ctctctttga tggtctcata aaaaaagttt 58740
tacaaaaata tttttattct ctttctctct ttgatggtct cataaaaaaa gttttacaaa 58800
aatattttta ttctctttct ctctttgatg gtctcataaa aaaagtttta caaaaatatt 58860
tttattctct ttctctcttt gatggtctca taaaaaaagt tttacaaaaa tatttttatt 58920
ctctttctct ctttgatggt ctcataaaaa aagttttaca aaaatatttt tattctcttt 58980
ctctctttga tggtctcata aaaaaagttt tacaaaaata tttttattct ctttctctct 59040
ttgatggtct cataaaaaaa gttttacaaa aatattttta ttctctttct ctctttgatg 59100
gtctcataaa aaatattaaa cctctttctg atggtgtcac taaaatattt ttattctctt 59160
tctctcttca atggagtcat aaaatatttt tattctcttt ctctcttcga tggtctcaca 59220
aaaatattaa acctctttct gatggtgtca ctaaaatatt tttattctca ttctctcttc 59280
aatggagtca taaaatattt ttattctctt tctctctttg atggtctcat aaaaaaagtt 59340
ttacaaaaat atttttattc tctttctctc tttgatggtc tcataaaaaa agttttacaa 59400
aaatattttt attctctttc tctctttgat ggtctcataa aaaaagtttt acaaaaatat 59460
ttttattctc tttctctctt tgatggtctc ataaaaaaag ttttacaaaa atatttttat 59520
tctctttctc tctttgatgg tctcataaaa aaagttttac aaaaatattt ttattctctt 59580
tctctctttg atggtctcat aaaaaatatt aaacctcttt ctgatggtgt cactaaaata 59640
tttttattct ctttctctct tcaatggagt cataaaatat ttttattctc tttctctctt 59700
cgatggtctc acaaaaatat taaacctctt tctgatggtg tcactaaaat atttttattc 59760
tctttctctc ttcaatggag tcataaaata tttttattct ctttctctct ttgatggtct 59820
cataaaaaaa gttttacaaa aatattttta ttctctttct ctctttgatg gtctcataaa 59880
aaaagtttta caaaaatatt tttattctct ttctctcttt gatggtctca taaaaaaagt 59940
tttacaaaaa tatttttatt ctctttctct ctttgatggt ctcataaaaa aagttttaca 60000
aaaatatttt tattctcttt ctctctttga tggtctcata aaaaaagttt tacaaaaata 60060
tttttattct ctttctctct ttgatggtct cataaaaaaa gttttacaaa aatattttta 60120
ttctctttct ctctttgatg gtctcataaa aaaagtttta caaaaatatt tttattctct 60180
ttctctcttt gatggtctca taaaaaatat taaacctctt tctgatggtg tcactaaaat 60240
atttttattc tcattttctc tttctctctt caatggagtc ataaaatatt tttattctct 60300
ttctctcttt gatggtctca taaaaaatat taaacctctt tctgatggtg tcactaaaat 60360
atttttattc tcattctctc ttcaatggag tcataaaaaa gttttatctc tttctctctt 60420
cgatggtctc acaaaaatat taaacctctt tctgatggag tcgtaaaaaa gttttatctc 60480
tttctctctt cgatggtctc acaaaaatat taaacctctt tctgatgcat caactatttc 60540
ttaaacaata acgtccaaca acatatactc atcccctatg cccatctagg ttaccagaca 60600
attgtatatc ataaaataat gtttataatt tacacgttaa aatcatataa taaaacgtag 60660
atcgtataat attttttggt atataaatga tctagtaaaa tccatgtagg ggatactgct 60720
cacatttttt ctttggtaca aaatttcaca caagttttta tacagacaaa ttcttgtcca 60780
tatattttaa aacattgact tttgtactaa gaaaaatatc tagactaact atctctttct 60840
ctttctctct tcgatggtct ttctgatgga gtcgtaaaaa agttttatct ctttctctct 60900
tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct 60960
ctttctctct tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa 61020
agttttatct ctttctcctt cgatggtctc acaaaaatat taaacctctt tctgatggag 61080
tcgtaaaaaa gttttatctc tttctctctt cgatggtctc acaaaaatat taaacctctt 61140
tctgatggtg tcactaaaat atttttattc tctttctctc ttcgatggtc tcacaaaaat 61200
attaaacctc tttctgatgg agtcgtaaaa aagttttatc tctttctcct tcgatggtct 61260
cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct ctttctctct 61320
tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct 61380
ctttctcctt cgatggtctc acaaaaatat taaacctctt tctgatggag tcgtaaaaaa 61440
gttttatctc tttctccttc gatggtctca caaaaatatt aaacctcttt ctgatggagt 61500
cgtaaaaaag ttttatctct ttctccttcg atggtctcac aaaaatatta aacctctttc 61560
tgatggagtc gtaaaaaagt tttatctctt tctctcttcg atggtctcac aaaaatatta 61620
aacctctttc tgatggagtc gtaaaaaagt tttatctctt tctctcttcg atggtctcac 61680
aaaaatatta aacctctttc tgatggagtc gtaaaaaagt tttatctctt tctccttcga 61740
tggtctcaca aaaatattaa acctctttct gatagtctct ataaagcgat tgatttttct 61800
taccctctag agtttcctac ggtcgttggt cacacatttt tttctagaca ctaaataaat 61860
agtaagatta aattaattat aaaattatgt atataatatt aattataaaa ttatgtatat 61920
gatttactaa ctttagttag ataaattaat aatacataaa ttttagtata ttaatattat 61980
aaattaataa tacataaatt ttagtatatt aatattatat tttaaatatt tatttagtgt 62040
ctagaaaaaa aggccggcct agcaggcc 62068
<210> 16
<211> 66679
<212> DNA
<213> 人工序列
<220>
<223> sVAC片段1
<400> 16
tttttttcta gacactaaat aaaatattta aaatataata ttaatgtact aaaacttata 60
tattattaat ttatctaact aaagttagta aattatatat ataattttat aattaattta 120
attttactaa ttttatttag tgtctagaaa aaaatgtgtg acccatgact gtaggaaact 180
ctagagtgta agaaagatcg atcgctttat agagaccatc agaaagaggt ttaatatttt 240
tgtgagacca tcgaagagag aaagagataa aactttttta cgactccatc agaaagaggt 300
ttaatatttt tgtgagacca tcgaagagag aaagagataa aactttttta cgactccatc 360
agaaagaggt ttaatatttt tgtgagacca tcgaaggaga aagagataaa acttttttac 420
gactccatca gaaagaggtt taatattttt gtgagaccat cgaaggagaa agagataaaa 480
cttttttacg actccatcag aaagaggttt aatatttttg tgagaccatc gaagagagaa 540
agagataaaa cttttttacg actccatcag aaagaggttt aatatttttg tgagaccatc 600
gaagagagaa agagataaaa cttttttacg actccatcag aaagaggttt aatatttttg 660
tgagaccatc gaaggagaaa gagataaaac ttttttacga ctccatcaga aagaggttta 720
atatttttgt gagaccatcg aagagagaaa gagataaaac ttttttacga ctccatcaga 780
aagaggttta atatttttgt gagaccatcg aagagagaaa gagataaaac ttttttacga 840
ctccatcaga aagaggttta atatttttgt gagaccatcg aagagagaaa gagataaaac 900
ttttttacga ctccatcaga aagaggttta atatttttgt gagaccatcg aagagagaaa 960
gagataaaac ttttttacga ctccatcaga aagaggttta atatttttgt gagaccatcg 1020
aagagagaaa gagataaaac ttttttacga ctccatcaga aagaggttta atatttttgt 1080
gagaccatcg aagagagaaa gagaaagaga tagttgatct agatattttt cttagtacaa 1140
aagtcaatgt tttaaaatat atggacaaga atttgtctgt ataaaaactt gtgtgaaatt 1200
ttgtaccaaa gaaaaaatgt gagcagtatc ccctacatgg attttactag atcatttata 1260
taccaaaaaa tattatacga tctacgtttt attatatgat tttaacgtgt aaattataaa 1320
cattatttta tgatatacaa ttgtctggta acctagatgg gcatagggga tgttgataag 1380
ctcgacgagt atatgttgtt ggacgttatt gtttaagaaa tagttgatgc atcagaaaga 1440
gaataaaaaa tattttagtg agaccatcga agagagaaag agataaaact tttttacgac 1500
tccatcagaa agaggtttaa tatttttgtg agaccatcga agagagaaag agataaaact 1560
tttttacgac tccatcagaa agaggtttaa tatttttgtg agaccatcga agagagaaag 1620
agataaaact tttttacgac tccatcagaa agaggtttaa tatttttgtg agaccatcga 1680
agagagaaag agataaaact tttttacgac tccatcagaa agaggtttaa tatttttgtg 1740
agaccatcga agagagaaag agataaaact tttttacgac tccatcagaa agaggtttaa 1800
tatttttgtg agaccatcga agagagaaag agataaaact tttttacgac tccatcagaa 1860
agaggtttaa tatttttgtg agaccatcga agagagaaag agataaaact tttttacgac 1920
tccatcagaa agaggtttaa tatttttgtg agaccatcga agagagaaag agataaaact 1980
tttttacgac tccatcagaa agaggtttaa tatttttgtg agaccatcga agagagaaag 2040
agataaaact tttttacgac tccatcagaa agaggtttaa tatttttgtg agaccatcga 2100
agagagaaag agataaaact tttttacgac tccatcagaa agaggtttaa tatttttgtg 2160
agaccatcga agagagaaag agataaaact tttttacgac tccatcagaa agaggtttaa 2220
tatttttgtg agaccatcga agagagaaag agataaaact tttttacgac tccatcagaa 2280
agaggtttaa tatttttgtg agaccatcga agagagaaag agataaaact tttttacgac 2340
tccatcagaa agaggtttaa tatttttgtg agaccatcga agagagaaag agataaaact 2400
tttttacgac tccatcagaa agaggtttaa tatttttgtg agaccatcga agagagaaag 2460
agataaaact tttttacgac tccatcagaa agaggtttaa tatttttgtg agaccatcga 2520
agagagaaag agataaaact tttttacgac tccatcagaa agaggtttaa tatttttgtg 2580
agaccatcga agagagaaag agataaaact tttttacgac tccatcagaa agaggtttaa 2640
tatttttgtg agaccatcga agagagaaag agataaaact tttttacgac tccatcagaa 2700
agaggtttaa tatttttgtg agaccatcga agagagaaag agaataaaaa tattttatga 2760
ctccattgaa gagagaaaga gaaaatgaga atgagaataa aaatatttta gtgacaccat 2820
cagaaagagg tttaatattt ttgtgagacc atcgaagaga gaaagagaat aaaaatattt 2880
tatgactcca ttgaagagag aaagagaaaa tgagaatgag aataaaaata ttttagtgac 2940
accatcagaa agaggtttaa tattttttat gagaccatca aagagagaaa gagaataaaa 3000
atatttttgt aaaacttttt ttatgagacc atcaaagaga gaaagagaat aaaaatattt 3060
ttgtaaaact ttttttatga gaccatcaaa gagagaaaga gaataaaaat atttttgtaa 3120
aacttttttt atgagaccat caaagagaga aagagaataa aaatattttt gtaaaacttt 3180
ttttatgaga ccatcaaaga gagaaagaga ataaaaatat ttttgtaaaa ctttttttat 3240
gagaccatca aagagagaaa gagaataaaa atatttttgt aaaacttttt ttatgagacc 3300
atcaaagaga gaaagagaat aaaaatattt ttgtaaaact ttttttatga gaccatcaaa 3360
gagagaaaga gaataaaaat atttttgtaa aacttttttt atgagaccat cagaaagagg 3420
tttaatattt ttgtgatacc ctgaaaggaa ataggaatag gaataggaat agtgtcataa 3480
tcgtatcaca ctattgagac agaaaaagaa gaagtcgcga gaggtaactt tttgtgaatg 3540
tagttaagaa catttttgtt ttgcaaaccg gaatatagtg tccggtacac ttttttaatt 3600
cgtggtgtgc ctgaatcgtt cgattaaccc tactcatcca atttcagatg aatagagtta 3660
tcgattcaga cacacgcttt gagttttgtt gaatcgatga gtgaagtatc atcggttgca 3720
ccttcagatg ccgatccgtc gacatactta aatccatcct tgacctcaag ttcagatgat 3780
tccttgcaca tgtctccgat acgaacgcta aactctagat tcttgacaca ttttgtatcg 3840
acgatcgttg aaccgatgat atcttcgtaa ctcactttct tatgagagat gttagacccg 3900
agtactggat gggtcttgat gtcgctgtct ttctcttctt cgctacatct gatgtcgata 3960
gacacctcac agtctttgat catagccaga gcttcttcat gagtgatcgc gggagagtcc 4020
ttaccttgtc ctggggacac gctggacaat ctagcattca ctgtgtttcc atcagcggat 4080
tctgagatgg atttaatctg aggacatttg gtgaatccaa agttcattct cagacctcca 4140
ccgatgatgg agtaataagt ggtaggagga tctacatcct cgactgatgt ggaatcatct 4200
tctgattcca cctcgggatc tggatctgac tcggactctg taatttccgt tacggattgg 4260
caaatcttat cattggtcgg tgtttggtct tgctttgtga ctttgataat aacatcgatt 4320
cccatatgat gtttgttttc ttcttccgta cacgaggagg aggatgagga tgattgctga 4380
agactggcag gcacatgcat gccaggacga tatattgttt catgattgct attgattgag 4440
tactgttctt tatgattcta cttccttacc gtgcaataaa ttagaatata ttttctactt 4500
ttacgagaaa ttaattattg tatttattat ttatgggtga aaaacttact ataaaaagcg 4560
ggtgggtttg gaattagtga tcagtttatg tatatcgcaa ctaccgggca tatggctatc 4620
gacatcgaga acattaccca catgataaga gattgtatca gtttcgtagt cttgagtatt 4680
ggtattacta tatagtatat agatgtcgac gctagataga cagtctccga atgcggcatg 4740
ataccgtcat cattctttgc tttcgttaac tgtttggagg aaaaattttt gttattgcat 4800
ttaatctcga aattcagagt gcacaccttt ctcctgtaaa gaaacctgaa gttgctacct 4860
tattaaggac ggagaagtat tcctcacgaa atacgggatt acagtcttta tgattcatag 4920
taatagttag ttccgacgtt gagatggatt cgctgagacc ggtagtggtc gttaactgga 4980
tacagattaa tttccacatc gatatagtta aaggtattac tgggtacggg ttcgcattta 5040
tctgcggaag agacggtgtg agaatatgtt ccgagaccac acggagaaca gatgacgtct 5100
ccggatactc cgtatcctat tccacatttt gtttgggaaa cacatgcctt gcatccggat 5160
gatcctttga gaagacaata atatccggga gagcattcac agattctatt gtgagtcgtg 5220
ttacacggtc gcgtcttccg ttacaactta gacaagcggg taaatgatta ttgcgagatg 5280
tgaaggtacc cgaaccacac ggcgtacatt gtgtgttagt cttgctatcg cataatctgg 5340
aagcgtatgt tcccggacac aaattatggc gtttgtattc gttgtcttta cactttccat 5400
cggatggtgc atgcggtgct atatctcttc cgtttattat tatacatgag agaaacaata 5460
tatacgagta taatacggac ttcatgattt aataatgtag taatcgtcgt cttgttcctg 5520
tttcctactt ctccaatcat atagatattt tctttctatc atggataata tttgtaatgg 5580
ttcttttcgt acaacatact gtttagatga tattgcgcat aatttccgga ggcaaatacg 5640
atagtctaga ttgaccgatg gtagactcta atttattgag tgctttgtcg acgagtttac 5700
ttttacgctc catcgataga tggcactgtt ctatgagatc gtcgtacatg ggaaatgaaa 5760
tgtgactgtc tgaatgtatg gctttaagat agctgtgata ccgtatacag gtcggtgtcg 5820
gagattcgaa tctctttaag gcgacttatg tcacgatgat ggaatctatc ttatcgaatg 5880
atatattttt cataaataca cttttatagt cctcgtttaa acagaattta ctatgtagtt 5940
ccgcgaatga ctcgtccctt aataggcagt aggctattat cttctttacg tagtaatcgt 6000
cgtagggaga gacatcttgt agaacaacga tttaatcata ggtagagata ctttcagtct 6060
gtggtggatg atgtcattca caacatccgc cttgtatatg atgtttctgt tttcaaacac 6120
caagtcgaat accgtcttta gtcggaaggt tgatgtcgta tccgatgtat gaggcaacat 6180
tgttgttaca attttgaaag gcggtattat agtattcgtc tttctgaatg tcgaacctat 6240
ctagtagata ccgtagtata ttgagagtgt atccttgatt atgttttatg aatagataaa 6300
gtagatgttg tccttcttcc ttttgttcgt gccaattgag taacattatg agaatatgac 6360
ctgttgcaca atcgttccat gatgggtgta caatcaagat tattacgtat cctcgtatcg 6420
gctcctcgag ataaaagagc atacaccaca cgaggactat gtttggtata ctgttgaagg 6480
taagtgtgta accgcgttaa tgtttgctcc ataatctatt atcgcgtaga tgaatcgctt 6540
ctcggctcgc atcttagtgt gacttaactt gtaataattg cttttgtaga acgtggatat 6600
gtgtttacag tagtaatgaa gagaagtgag ttcatcctcg tcggatcctt tgtacagaac 6660
gtaatagttt aagctcccat tgaatttata tctaagataa cacagcaata gatcggatga 6720
tttactaaag tcatcaatgg tgtccgttag tatatcaaag atcttgttat cgattgatag 6780
tggtgtcctt tttcatcctt gctatcaaag ttacgcatgc cgtggtgtaa caatatcttt 6840
aatacagatg gattaaatcg tgtattcatc gtatagcaat gtaatggaga gttacctcgt 6900
ttattcagat cgcagtgttt aataactagc ttaaacagat gagacgatgt atccacatca 6960
aagaacgtga aatacatatg acagacattg ttgacagaaa cgtgaccttc attcttaccg 7020
tcgtccataa atacgttagg tatgtaccac atactgtcgc gaacgatgcg tacaatctcg 7080
tccatctcat aatgatttac tttttcataa ttaaagatgt gaaagaaaaa cagaacaata 7140
tattttttta gtaatgttta tgcgagacat ataaaataaa ctccgtgttt atgatcattt 7200
ttaacagcaa cacattcaat attgtattgt tatttttata ttatttacac aattaacaat 7260
atattattag tttatattac tgaattaata atataaaatt cccaatcttg tcataaacac 7320
acactgagaa acagcataaa cacaaaatcc atcaaaaatg tcgatgaaat atctgatgtt 7380
gttgttcgct gctatgataa tcagatcatt cgccgatagt ggtaacgcta tcgaaacgac 7440
atcgccagaa attacaaacg ctacaacaga tattccagct atcagattat gcggtccaga 7500
gggagatgga tattgtttac acggtgactg tatccacgct agagatattg acggtatgta 7560
ttgtagatgc tctcatggtt atacaggcat tagatgtcag catgtagtat tagtagacta 7620
tcaacgttca gaaaacccaa acactacaac gtcatatatc ccatctcccg gtattatgct 7680
tgtattagta ggcattatta ttattacgtg ttgtctatta tctgtttata ggttcactcg 7740
acgaactaaa ctacctatac aagatatggt tgtgccataa tttttataaa tttttttatg 7800
agtattttta caaaaaaaat gtataaagtg tatgtcttat gtatatttat aaaaatgcta 7860
agtatgcgat gtatctatgt tatttgtatt tatctaaaca atacctctac ctctagatat 7920
tatacaaaaa ttttttattt cggcatatta aagtaaaatc tagttacctt gaaaatgaat 7980
acagtgggtg gttccgtatc accagtaaga acataatagt cgaatacagt atccgattga 8040
gattttgcat acaatactag tctagaaaga aatttgtaat catcttctgt gacgggagtc 8100
catatatctg tatcatcgtc tagtttatca gtgtcccatg ctatattcct gttatcatca 8160
ttagttaatg aaaataactc tcgtgcttca gaaaagtcaa atattgtatc catacataca 8220
tctccaaaac tatcgcttat acgtttatct ttaacgatac ctatacctag atggttattt 8280
actaacagac attttccaga tctattgact ataactccta tagtttccac atcaaccaag 8340
taatgatcat ctattgttat ataacaataa cataactctt ttccattttt atcagtatgt 8400
atatctatat caacgtcgtc gttgtagtga atagtagtca ttgatctatt atatgaaacg 8460
gatatgtcta gaacggcaat tgttttacgt ccagttaaca ctttctttga tttaaagtct 8520
agagtctttg caaacataat atccttatcc gactttatat ttcctgtagg gtggtataat 8580
tttattttgc ctccacatat cggtgtttcc aaatatatta ctagacaata ttccatatag 8640
ttattagtta agggtaccca attagaacac gtacgcttat tatcatcatt tggatcgtat 8700
ttcataaaag ttattgtact atcgatgtca acacattcta cattttttaa tcgtctatat 8760
agtatttttc tgatattttc tataatatca gaattgtctt ccatcggaag ttgtatacta 8820
tcggaatcag ttacatgttt aaataattct ctgatgtcat tccttataca atcaaattca 8880
ttattaaaca gtttaatagt ctgtagacct ttatcgtcgt aaatatccat tgtcttatta 8940
gttacgctta tttttatgtg ttttacgttg ctttattata ttttataaga atgattgttt 9000
gacgaatcac gagaactatt aagacacatt attaggtata tattataaaa aagtttttga 9060
ttacgatgtt ataagaggaa agaggacaca ttaacatcat acatcaatta actacattct 9120
tataacatcg taatcaaaag aattgcaatt ttgatgtata acaactgtca atgggttatg 9180
gaattgtata ttacatatta tacggtatgt tggtaacgac aaataccgat cggtaattgt 9240
ctgccggtgt aatagaatta tatatatcta tctattacac cggctgagta tgcataataa 9300
taagttgtgg tagtatgatc tccatattta taatttagga ctttgtattc agtatttttg 9360
gaatcataaa aaataaaaaa aagttttact aatttaaaat ttaaaaagta tttacatttt 9420
tttcactgtt tagtcgcgga tatggaattc gatcctgcca aaatcaatac atcatctata 9480
gatcatgtaa caatattaca atacatagat gaaccaaatg atataagact aacagtatgc 9540
attatccgaa atattaataa cattacatat tatatcaata tcacaaaaat aaatacacat 9600
ttggctaatc aatttcgggc ttggaaaaaa cgtatcgccg gaagggacta tatgactaac 9660
ttatctagag atacaggaat acaacaatca aaacttactg aaactatacg taactgtcaa 9720
aaaaatagaa acatatatgg tctatatata cactacaatt tagttattaa tgtggttatt 9780
gattggataa ccgatgtgat tgttcaatca atattaagag ggttggtaaa ttggtacata 9840
gctaataata cctatacacc caataataca acaaccattt ctgagttgga tatcatcaaa 9900
atactggata aatacgagga cgtgtataga gtaagtaaag aaaaagaatg tggaatttgc 9960
tatgaagttg tttactcaaa acgatagata ctttggttta ttggattcgt gtactcatat 10020
attttgcata acatgcatca atatatggca taaaacacga agagaaaccg gtgcgtcgga 10080
taattgtcct atatgtcgta cccgttttag aaacataaca atgagcaagt tctataagct 10140
agttaactaa taaataaaaa gtttaatttg ttgacgacgt atgtcgttat ttttctcgta 10200
tgaaagatta aattcaattc aattcgttgt ttctaatata atctgccgta ttggatggat 10260
tctcaagaca attgcattta gattatatta tcatgaataa aaatagtagc acgcactact 10320
tcagccaaat attctttttt gaaacgccat ctatcgtagt gaggacacaa gtgaacctat 10380
aattatcaaa tttattagta tcagtcacat gaaggacttt ctgtagagtg acgattctac 10440
catctatggt actaacggtt tcatcctcct tgataccctc acccaaatgt tctataaatt 10500
tagcatcctc gtccgatctc atatcctttg ccaaccaata catgtagcta aaattaggca 10560
taaatttcac acatccagtg caacgaaatt ctccagaaga tgttacgatg tttaggttag 10620
gacatttgat ttcgtcggca ttaacatatg ggtgaacaca cccatacatg aaagcgatga 10680
gaaataggat tctcatcttg ccaaaatatc actagaaaaa atttatttat caattttaaa 10740
ggtataaaaa atacttattg ttgctcgaat attttgtatt tgatggtata cggaagatta 10800
gaaatgtagg tattatcatc aactgattct atggttttat gtattctatc atgtttcact 10860
attgcgtcgg aaataatatc atatgcttcc acatatattt tattttgttt taactcataa 10920
tactcacgta attctggatt attggcatat ctatgaataa ttttagctcc atgatcagta 10980
aatattaatg agaacatagt attaccacct accattattt ttttcatttc gttcaattct 11040
tgattgcaaa gatctatata atcattatag cgttgactta tggactctgg aatcttagac 11100
gatgtacagt catctataat catggcatat ttaatacatt gttttatagc atagtagtta 11160
tctacgatgt tagatatttc tctcaatgaa tcaatcacac aatctaatgt aggtttatga 11220
cataatagca ttttcagcag ttcaatgttt ctagattcgt tgatggcaat ggctatacat 11280
gtatatccgt tatttgatct aatgttgaca tctgaaccgg attctagcag taaagatact 11340
agagattgtt tattatatct aacagccttg tgaagaagtg tttctcctcg tttgtcaatc 11400
atgttaatgt ctttaagata aggtaggcaa atgtttatag tactaagaat tgggcaagca 11460
taagacatgt cacaaagacc ctttttgtat gtataagtgt aaaaattata acattcatag 11520
ttggatttac ataggtgtcc aatcgggatc tctccatcat cgagataatt gatggcatct 11580
cccttccttt tttagtagat atttcatcgt gtaagaatca atattaatat ttctaaagta 11640
ttcgtgtata gcctctttat ttaccacagt tccatattcc actagaggga tatcgccgaa 11700
tgtcatatac tcaattagta tatgttggag gacatccgag ttcattgttt tcaatatcaa 11760
aaagatggtt tccttatcat ttctccatag tggtacaata ctacacatta ttccgtgcgg 11820
ctttccattt tccaaaaaca atttgaccaa atctaaatct acatctttat tgtatctata 11880
atcactattt agataatcag ccataattac tcgagtgcaa catgttagat cgtctatata 11940
tgaataagca gtgttatcta ttcctttcat taacaattta acgatgtcta tatctatatg 12000
agatgactta atataatatt gaagagctgt acaatagttt ttatctatag aagacggctt 12060
gattccgtga ttaattagac atttaacaac ttccggacgc acatatgctc tcgtatccga 12120
ctttgaatac agatgagaga tgatatacag atgcaatacg gtaccgcaat ttcgtagttg 12180
ataatcatca tacgcgtatc agtactcgtc ctcataaaga acactgcagc cattttctat 12240
gaacaaatca ataattttag gaacaggatc attgtcatta cataattttc tataactgaa 12300
cgatggtttt cacatttaac actcaagtca aatccatgtt ctaccaacac ctttatcaag 12360
tcaacgtcta catttttgga tttcatatag ctgaatatat taaagtcatt tatgttgcta 12420
aatccagtgg cttctagtag agccatcgct atatccttta actttaacat gtctactatt 12480
tgtgtattct tctaatgggg tagctgtctc caatttttgc gtaatggatt agtgccactg 12540
tctagtagta gtttgacgac ctcgacatta ttacaatgct cattaaaaag gtatgcgtgt 12600
aaagcattat tcttgaattg gttcctggta tcattaggat ctctgtctct caacatctgt 12660
ttaagttcat cgagagccac ctcctcattt tccagatagt caaacatttt gactgaatga 12720
gctactgtga actctataca cccacacaac taatgtcatt aaatattatt tttttgaatg 12780
tatttatacc atgtcaaaaa cttgtacaat tattaataaa aataatttag tgtttaaatt 12840
ttaccagttc cagattttac acctccgtta accccacttt ttacaccact ggacgatcct 12900
cctccccaca ttccaccgcc accagatgta taagttttag atcctttatt actaccatca 12960
tgtccatgga taaagacact ccacatgccg ccactactac cccctttaga agacatatta 13020
ataagactta aggacaagtt taacaataaa attaatcacg agtaccctac taccaaccta 13080
cactattata tgattatagt ttctattttt acagtacctt aactaaagtc tctagtcaca 13140
agagcaatac taccaaccta cactattata tgattatagt ttctattttt ataggaacgc 13200
gtacgagaaa atcaaatgtc taatttctaa cggtagtgtt gataaacgat tatcgtcaat 13260
ggatacctcc tctatcatgt cgtctatttt cttactttgt tctattaact tattagcatt 13320
atatattatt tgattataaa acttatattg cttattagcc caatctgtaa atatcggatt 13380
attaacatat cgtttctttg taggtttatt taacatgtac atcactgtaa gcatgtccgt 13440
accatttatt ttaatttgac gcatatccgc aatttctttt tcgcagtcgg ttataaattc 13500
tatatatgat ggatacatgc tacatgtgta cttataatcg actaatatga agtacttgat 13560
acatattttc agtaacgatt tattattacc acctatgaat aagtacctgt gatcgtctag 13620
gtaatcaact gttttcttaa tacattcgat ggttggtaat ttactcagaa taatttccaa 13680
tatcttaata tataattctg ctatttctgg gatatattta tctgccagta taacacaaat 13740
agtaatacat gtaaacccat attttgttat tatattaatg tctgcgccat tatctattaa 13800
ccattctact aggctgacac tatgcgactt aatacaatga taaagtatac tacatccatg 13860
tttatctatt ttgtttatat catcaatata cggcttacaa agttttagta tcgataacac 13920
atccaactca cgcatagaga aggtagggaa taatggcata atatttatta ggttatcatc 13980
attgtcatta tctacaacta agtttccatt ttttaaaata tactcgacaa ctttaggatc 14040
tctattgcca aatttttgaa aatatttatt tatatgctta aatctatata atgtagctcc 14100
ttcatcaatc atacatttaa taacattgat gtatactgta tgataagata catattctaa 14160
caatagatct tgtatagaat ctgtatatct tttaagaatt gtggatatta ggatattatt 14220
acgtaaacta ttacacaatt ctaaaatata aaacgtatca cggtcgaata atagttgatc 14280
aactatataa ttatcgattt tgtgattttt cttcctaaac tgtttacgta aatagttaga 14340
tagaatattc attagttcat gaccactata gttactatcg aataacgcgt caaatatttc 14400
ccgtttaata tcgcatttgt caagataata atagagtgtg gtatgttcac gataagtata 14460
ataacgcatc tcttttttgt gtgaaattaa atagtttatc acgtccaaag atgtagcata 14520
accatcttgt gacctagtaa taatataata atagagaact gttttaccca ttctatcatc 14580
ataatcagtg gtgtagtcgt aatcgtaatc gtctaattca tcatcccaat tataatattc 14640
accagcacgt ctaatctgtt ctattttgat cttgtatcca tactgtatgt tgctacatgt 14700
aggtattcct ttatccaata atagtttaaa cacatctaca ttgggatttg atgttgtagc 14760
gtatttctct acaatattaa taccattttt gatactattt atttctatac ctttcgaaat 14820
tagtaatttc aataagtcta tatcgatgtt atcagaacat agatattcga atatatcaaa 14880
atcattgata tttttatagt cgactgacga caataacaaa atcacaacat cgtttttgat 14940
attattattt ttcttggtaa cgtatgcctt taatggagtt tcaccatcat actcatataa 15000
tggatttgca ccactttcta tcaatgattg tgcactgctg gcatcgatgt taaatgtttt 15060
acaactatca tagagtatct tatcgttaac catgattggt tgttgatgct atcgcatttt 15120
ttggtttctt tcatttcagt tatgtatgga tttagcacgt ttgggaagca tgagctcata 15180
tgatttcagt actgtagtgt cagtactatt agtttcgatc agatcaatgt ctagatctat 15240
agaatcaaaa cacgataggt cagaagataa tgaatatctg tacgcttctt tttgtactgt 15300
aacttctggt tttgttagat ggttgcatcg tgctttaaca tcaatggtac aaattttatc 15360
ctcgctttgt gtatcatatt cgtctctagt ataaaattct atattcagat tatcatgcga 15420
tgtgtatacg ctaacggtat caataaacgg agcacaccat ttagtcataa cagtaatcca 15480
aaatttttta aagtatatct taacgaaaga agttgtgtca ttgtctacgg tgtatggtac 15540
tagatcctca taagtgtata tatctagagt aatgtttaat ttattaaatg gttgataata 15600
tggatcctca tgacaatttc cgaagatgga aatgagatat agacatgcaa taaatctaat 15660
cgaagacatg gttactcctt aaaaaaatac gaataatcac cttggctatt tagtaagtgt 15720
catttaacac tatactcata ttaatccatg gactcataat ctctatacgg gattaacgga 15780
tgttctatat acggggatga gtagttttct tctttaactt tatacttttt actaatcata 15840
tttagactga tgtatgggta atagtgttta aagagttcgt tctcatcatc agaataaatc 15900
aatatctctg tttttttgtt atacagatgt attacagcct catatattac gtaatagaac 15960
gtgtcatcta ccttattaac tttcaccgca tagttgtttg caaatacggt taatcctttg 16020
acctcgtcga tttccgacca atctgggcgt ataatgaatc taaactttaa tttcttgtaa 16080
tcattcgaaa taatttttag tttgcatccg tagttatccc ctttatgtaa ctgtaaattt 16140
ctcaacgcga tatctccatt aataatgatg tcgaattcgt gctgtatacc catactgaat 16200
ggatgaacta acgaatatca acggcgttaa tagtaattta ctttttcatc tttacatatt 16260
gggtactagt tttactatca taagtttata aattccacaa gctactatgg aataagccaa 16320
ccatcttagt ataccacaca tgtcttaaag tttattaatt aattacatgt tgttttatat 16380
atatcgctac gaatttaaag agaaatcagt ttaggaagaa aaaaattatc tatctacatc 16440
atcacgtctc tgtattctac gatagagtgc tactttaaga tgagacatat ccgtgtcatc 16500
aaaaatatac tccattaaaa tgattattcc ggcagcgaac ttgatattgg atatatcaca 16560
acctttgtta atatctacga caatagacag cagtcccatg gttccataaa cagtgagttt 16620
atctttcttt gaagcgatag tttgtagaga tcttataaaa ccgtcaaacg acatcgcatt 16680
tatatcttta gctaattcat atatgttacc atcgtaatat ctaaccgcgt ctatcttaaa 16740
cgtttccatc gctttaaaga cgtttccgat agatggtctc atttcatcag tcatactgag 16800
ccaacaaata taatcgtgta taacatcttt gatagaatca gactctaaag aaaacgaatc 16860
ggctttatta tacgcattca tgataaactt aatgaaaaat gtttttcgtt gtttaagttg 16920
gatgaatagt atgtcttaat aattgttatt atttcattaa ttaatattta gtaacgagta 16980
cactctataa aaacgagaat gacataacta gttatcaaag tgtctaggac gcgtaatttt 17040
catatggtat agatcctgta agcattgtct gtattctgga gctattttct ttatcgcatt 17100
agtaagttca gaatatgtta taaatttaaa tcgaataacg aacatgactt tagtaaagtc 17160
gtctatatta actcttttat tttctagcca tcgtaatacc atgtttaaga tagtatattc 17220
tctagttact acgatctcat cgttgtctag aatatcacat actgaatcta catccaattt 17280
tagaaattgg tctgtgttac atatctcttc tatattattg ttgatgtatt gtcgtagaaa 17340
actattacgt agaccatttt ctttataaaa cgaatatata gtactccaat tatctttacc 17400
gatatatttg cacacataat ccattctctc aatcactaca tctttaagat tttcgttgtt 17460
aagatatttg gctaaactat ataattctat tagatcatca acagaatcag tatatatttt 17520
tctagatcca aagacgaact ctttggcgtc ctctataata ttcccagaaa agatattttc 17580
gtgttttagt ttatcgagat ctgatctgtt catatacgcc atgattgtac ggtacgttat 17640
gataaccgca taaaataaaa atccattttc atttttaacc aatactattc ataattgaga 17700
ttgatgtaat actttgttac tttgaacgta aagacagtac acggatccgt atctccaaca 17760
agcacgtagt aatcaaattt ggtgttgtta aacttcgcaa tattcatcaa tttagataga 17820
aacttatact catcatctgt tttaggaatc catgtattat taccactttc caacttatca 17880
ttatcccagg ctatgtttcg tccatcatcg ttgcgcagag tgaataattc ttttgtattc 17940
ggtagttcaa atatatgatc catgcataga tcggcaaagc tattgtagat gtgatttttc 18000
ctaaatctaa tataaaactc gtttactagc aaacactttc ctgatttatc gaccaagaca 18060
catatggttt ctaaatctat caagtggtgg ggatccatag ttatgacgca gtaacataga 18120
ttattacatt cttgactgtc gctaatatct aaatatttat tgttatcgta ttggattctg 18180
catatagatg gcttgtatgt caaagatata gaacacataa ccaatttata gtcgcgcttt 18240
acattctcga atctaaagtt aagagattta gaaaacatta tatcctcgga tgatgttatc 18300
actgtttctg gagtaggata tattaaagtc tttacagatt tcgtccgatt caaataaatc 18360
actaaataat atcccacatt atcatctgtt agagtagtat cattaaatct attatatttt 18420
atgaaagata tatcactgct cacctctata tttcgtacat ttttaaactg tttgtataat 18480
atctctctga tacaatcaga tatatctatt gtgtcggtag acgataccgt tacatttgaa 18540
ttaatggtgt tccattttac aacttttaac aagttgacca attcatttct aatagtatca 18600
aactctccat gattaaatat tttaatagta tccattttat atcactacgg acacaaagta 18660
gctgacataa accattgtat aatttttatg ttttatgttt attagcgtac acattttgga 18720
agttccggct tccatgtatt tcctggagag caagtagatg atgaggaacc agatagttta 18780
tatccgtact tgcacttaaa gtctacattg tcgttgtatg agtatgatct tttaaacccg 18840
ctagacaagt atccgtttga tattgtagga tgtggacatt taacaatctg acacgtgggt 18900
ggatcggacc attctcctcc tgaacacagg acaccagagt taccaatcaa cgaatatcca 18960
ctattgcaac tataagttac aacgctccca tcggtataaa aatcctcgta tccgttatgt 19020
cttccgttgg atatagatgg aggggattgg catttaacag attcacaaat aggtgcctcg 19080
ggattccata ccatagatcc agtagatcct aattcacaat acgatttaga ttcaccgatc 19140
aaatgatatc cgctattaca agagtacgtt atactagagc caaagtctac tccaccaata 19200
tcaagttggc cattatcgat atctcgaggc gatgggcatc tccgtttaat acattgatta 19260
aagagtgtcc atccagtacc tgtacattta gcatatatag gtcccatttt ttgctttctg 19320
tatccaggta gacatagata ttctatagtg tctcctatgt tgtaattagc attagcatca 19380
gtctccacac tattcttaaa tttcatatta atgggtcgtg acggaatagt acagcatgat 19440
agaacgcatc ctattcccaa caatgtcagg aacgtcacgc tctccacctt catatttatt 19500
tatccgtaaa aatgttatcc tggacatcgt acaaataata aaaagcccat atatgttcgc 19560
tattgtagaa attgtttttc acagttgctc aaaaacgatg gcagtgactt atgagttacg 19620
ttacactttg gagtctcatc tttagtaaac atatcataat attcgatatt acgagttgac 19680
atatcgaaca aattccaagt atttgatttt ggataatatt cgtattttgc atctgctata 19740
attaagatat aatcaccgca agaacacacg aacatctttc ctacatggtt aaagtacatg 19800
tataattcta tccatttgtc ttccttaact atatatttgt atagataatt acgagtctcg 19860
tgagtaattc cagtaattac atagatgtcg ccgtcgtact ctacagcata aactatacta 19920
tgatgtctag gcatgggaga cttttttatc caacgatttt tagtgaaaca ttccacatcg 19980
tttaatacta catatttttc atacgtggta taaactccac ccattacata tatatcatcg 20040
tttacgaata ccgacgcgcc tgaatatcta ggagtaatta agtttggaag tcttatccat 20100
ttcgaagtgc cgtgtttcaa atattctgcc acacccgttg aaatagaaaa ttctaatcct 20160
cctattacat ataactttcc atcgttaaca caagtactaa cttctgattt taacgacgac 20220
atattagtaa ccgttttcca ttttttcgtt tcaagatcta cccgcgatac ggaataaaca 20280
tgtctattgt taatcatgcc gccaataatg tatagacaat tatgtaaaac atttgcatta 20340
tagaattgtc tatctgtatt accgactatc gtccaatatt ctgttctagg agagtaatgg 20400
gttattgtgg atatataatc agagttttta atgactacta tattatgttt tataccattt 20460
cgtgtcactg gctttgtaga tttggatata gttaatccca acaatgatat agcattgcgc 20520
atagtattag tcataaactt gggatgtaaa atgttgatga tatctacatc gtttggattt 20580
ttatgtatcc actttaataa tatcatagct gtaacatcct catgatttac gttaacgttt 20640
tcgtgggata agatagttgt cagttcatcc tttgataatt ttccaaattc tggatcggat 20700
gtcaccgcag taatattgtt gattatttct gacatcgacg cattatatag ttttttaatt 20760
ccatatcttt tagaaaagtt aaacatcctt atacaatttg tggaattaat attatgaatc 20820
atagttttta cacatagatc tactacaggc ggaacatcaa ttattatggc agcaactagt 20880
atcatttcta cattgtttat ggtgatgttt atcttcttcc agcgtatata gtctaatagc 20940
gattcaaacg cgtgatagtt tataccattc aatataatcg cttcatcctt tagatggtga 21000
tcctgaattc gtttaaaaaa attatacgga gatgccgtaa taatttcctt attcacttgt 21060
ataatttccc cattgataga aaatatcacg ctttccattc ttgaagtact ataagtaatt 21120
atagtataat gtaaaggttt atatattcaa tattttttat aaaaaaatca ttttgacatt 21180
aattcctttt taaatttccg tctatcatct atagaaacgt attctatgaa tttataaaat 21240
gcttttacgt gtcctatcgt aggcgataga accgctaaaa agcctatcga atttctacaa 21300
aagaatctgt tatatggtat agggagagta taaaacatta aatgtccgta cttattaaag 21360
tattcagtag ccaatcctaa ctctttcgaa tacttattaa tggctcttgt tctgtacgaa 21420
tctatttttt tgaacaacgg acctagtggt atatcttgtt ctatgtatct aaaataatgt 21480
ctgactagat ccgttagttt aatatcctca gtcatcttgt ctagaatggc aaatctaact 21540
gcgggtttag gctttagttt agtttttata tctacatcta tgtctttatc taacaccaaa 21600
aatataatag ctaatatttt attacaatca tccggatatt cttctacgat ctcactaact 21660
aatgtttctt tggttatact agtatagtca ctatcggaca aataaagaaa atcagatgat 21720
cgatgaataa tacatttaaa ttcatcatct gtaagatttt tgagatgtct cattaaaata 21780
ttattagggt cagtactcat tatcattcgg cagctattac ttattttatt tttctgtatt 21840
ttattatttt tcaccatata gatcaatcat tagatcatca aaatatgttt caatcatcct 21900
aaagagtatg gtgaatgact cttcccatct aatttctgaa cgttcaccaa tgtctctagc 21960
cactttggca ctaatagcga tcattcgctt agcgtcttct atattattaa ctggttgatt 22020
caatctatct agcaatggac cgtcggacag cgtcattctc atgttcttaa tcaatgtaca 22080
tacatcgccg tcatctacca attcatccaa caacataagc tttttaaaat catcattata 22140
ataggtttga tcgttgtcat ttctccaaag aatatatcta ataagtagag tcctcatgct 22200
tagtaattta actattttag ttaacaacta ttttttatgt taaatcaatt agtacaccgc 22260
tatgtttaat acttattcat attttagttt ttaggattga gaatcaatac aaaaaattaa 22320
tgcatcatta attttagaaa tacttagttt ccacgtagtt aatgaaacat ttgaactcat 22380
cgtacaggac gttctcgtac aggacgtaac tataaaccgg tttatatttg ttcaagatag 22440
atacaaatcc gataactttt tttacgaatt ctacgggatc cactttaaaa gtgtcatacc 22500
gggttctttt tattctttta aacagatcaa tggtgtgatg ttgattaggt cttttacgaa 22560
tttgatatag aatagcgttc acatatcctc cataatggtc aatcgccatt tgttcgtatg 22620
tcataaattc tttaattata tgacactgtg tattatttag ttcatccttg ttcatcatta 22680
ggaatctatc caaaatggca attatactag aactataggt gcgttgtata cacatattga 22740
tgtgtctgtt tatacaatcc atgatatttg gatccatgct actaccttcg ggtaaaattg 22800
tagcatcata taccatttct agtactttag gttcattatt atccattgca gaggacgtca 22860
tgatcgaatc ctaaaaaaat atattatttt tatgttattt tgttaaaaat aatcatcgaa 22920
tacttcgtaa gatactcctt catgaacata atcagttaca aaacgtttat atgaagtaaa 22980
gtatctacga tttttacaaa agtccggatg cataagtaca aagtacgcga taaacggaat 23040
aataatagat ttatctagtc tatctttttc tatagctttc atagttagat acatggtctc 23100
agaagtagga ttatgtaaca tcagcttcga taaaatgact gggttattta gtcttacaca 23160
ttcgctcata catgtatgac cgttaactac aaagtctaca ctaaaatgat tgaacaatag 23220
atagtctacc attgtttcgt attcagatag tacagcgtag tacatagcat cttcacaaat 23280
tatatcattg tctaatagat atttgacgca tcttatggat cccacttcaa cagccatctt 23340
aaaatcggta gaatcatatt gctttccttt atcattaata atttctaaaa catcatctct 23400
atcataaaag atacaaatat taactgtttg atccgtaata acattgctag tcgatagcaa 23460
tttgttaata agatgcgctg ggctcaatgt cttaataaga agtgtaagag gactatctcc 23520
gaatttgttt tgtttattaa catccgttga tggaagtaaa agatctataa tgtctacatt 23580
cttgactgtt ttagagcata caatatggag aggtgtattt ccatcatgat ctggttttga 23640
gggactaatt cctagtttca tcatccatga gattgtagaa gcttttggat tgtctgacat 23700
aagatgtcta tgaatatgat ttttgccaaa tttatccact atcctggctt cgaatccgat 23760
ggacattatt tttttaaaca ctctttctga aggatctgta cacgccaaca acggaccaca 23820
tccttcttca tcaaccgagt tgttaatctt ggctccatac tgtaccaata aatttattct 23880
ctctatgact tcatcatctg ttcccgagag ataatataga ggtgttttat tatgtttatc 23940
acacgcgttt ggatctgcgc cgtgcgtcag cagcatcgcg actattctat tattattaat 24000
tttagaagct atatgcaatg gataatttcc atcatcatcc gtctcatttg gagagtatcc 24060
tctatgaaga agttcttcga caaatcgttc atctagtcct ttaattccac aatacgcatg 24120
tagaatgtga taattatttc cagaaggttc gatagcttgt agcatattcc taaatacatc 24180
taaattttta ctattatatt tggcataaag agatagataa tactcggccg acataatgtt 24240
gtccattgta gtataaaaat taatatttct atttctattt ctgtatattt gcaacaattt 24300
actctctata acaaatatca taacttagtt cttttatgtc aagaaggcac tggtttagtt 24360
catctataaa tgtcacgcca taactaccac gcatgctata ctcagaatta tgataaagat 24420
atttatcctt ggggtgtagg taatggggat taatctttgt tggatcagtc tctaagttaa 24480
cacatgtcac acatgatcca tttatagtta tatcacacga tgatgattta tgaattgatt 24540
ccggaagatc gctatcgtat tttgtggttc cacaattcat ttccatacat gttattgtca 24600
cactaatatt atgatgaact ttatctagcc gctgagtggt aaacaacaga acagatagtt 24660
tattatcttt accaacaccc tcagccgctg ccacaaatct ctgatccgta tccatgatgg 24720
tcatgtttat ttctagtccg tatccagtca acactatgtt agcatttctg tcgatatagc 24780
tttcactcat atgacactca ccaataatag tagaattaat gtcgtaattt acaccaatag 24840
tgagttcggc ggcaaagtac caataccggt aatcttgtcg aggaggacat atagtattct 24900
tgtattctac cgaatacccg agagatgcga tacaaaagag taagactaat ttgtaaacca 24960
tcttactcaa aatatgtaac aatagtacga tgcaatgagt aagacaatag gaaatctatc 25020
ttatatacac ataattattc tatcaatttt accaattagt tagtgtaatg ttaacaaaaa 25080
tgtgggagaa tctaattagt ttttctttac acaattgacg tacatgagtc tgagttcctt 25140
gtttttgcta attatttcat ccaatttatt attcttgact atatcgagat cttttgtata 25200
ggagtcagac ttgtattcaa catgcttttc tataatcatt ttagctattt cggcatcatc 25260
caatagtaca ttttccagat tagcagaata gatattaatg tcgtatttga acagagcctg 25320
taacatctca atgtctttat tatctatagc caatttaatg tccggaatga agagaaggga 25380
attattggtg tttgtcgacg tcatatagtc gagcaagaga atcatcatat ccacgtgtcc 25440
attttttata gtgatgtgaa tacaactaag gagaatagcc agatcaaaag tagatggtat 25500
ctctgaaaga aagtaggaaa caatacttac atcattaagc atgacggcat gataaaatga 25560
agttttccat ccagttttcc catagaacat cagtctccaa tttttcttaa caaacagttt 25620
taccgtttgc atgttaccac tatcaaccgc ataatacaat gcggtgtttc ccttgtcatc 25680
aaattgtgaa tcatccagtc cactgaatag caaaatcttt actattttgg tatcttccaa 25740
tgtggctgcc tgatgtaatg gaaattcatt ctctagaaga tttttcaatg ctccagcgtt 25800
caacaacgta catactagac gcacgttatt atcagctatt gcataataca aggcactatg 25860
tccatggaca tccgccttaa atgcatcttt gctagagaga aagcttttca gctgcttaga 25920
cttccaagta ttaattcgtg acagatccat gtctgaaacg agacgctaat tagtgtatat 25980
tttttcattt tttataattt tgtcatattg caccagaatt aataatatct ctaatagatc 26040
tgattagtag atacatggct atcgcaaaac aacatataca catttaataa aaataatatt 26100
tattaagaaa attcagattt cacgtaccca tcaatataaa taaaataatg attccttaca 26160
ccgtacccat attaaggaga ttccacctta cccataaaca atataaatcc agtaatatca 26220
tgtctgatga tgaacacaaa tggtgtatta aattccagtt tttcaggaga tgatctcgcc 26280
gtagctacca taatagtaga tgcctctgct acagttcctt gttcgtcgac atctatcttt 26340
gcattctgaa acattttata aatatataat gggtccctag tcatatgttt aaacgacgca 26400
ttatctggat taaacatact aggagccatc atttcggcta tcgacttaat atccctctta 26460
ttttcgatag aaaatttagg gagtttaaga ttgtacactt tattccctaa ttgaaacgac 26520
caatagtcta attttgcagc cgtaatagaa tctgtgaaat gggtcatatt atcacctatt 26580
gccaggtaca tactaatatt agcatcctta tacggaaggc gtaccatatc atattcttcg 26640
tcatcgattg tgattgtatt tccttgcaat ttagtaacta cgttcatcat gggaaccgtt 26700
ttcgtaccgt acttattagt aaaactagca ttgcgtgttt tagtgatatc aaacggatat 26760
tgccatatac ctttaaaata tatagtatta atgattgccc atagagtatt attgtcgagc 26820
atattagaat ctactacatt agacataccg gatctacgtt ctactataga attaatttta 26880
ttaaccgcat ctcgtctaaa gtttaatcta tataggccga atctatgata ttgttgataa 26940
tacgacggtt taatgcacac agtattatct acgaaacttt gataagttag atcagtgtac 27000
gtatatttag atgttttcag cttagctaat cctgatatta attctgtaaa tgctggaccc 27060
agatctcttt ttctcaaatc catagtcttc aataattcta ttctagtatt acctgatgca 27120
ggcaatagcg acataaacat agaaaacgaa taaccaaacg gtgagaagac aatattatca 27180
tcttgaatat ttttatacgc tactataccg gcattggtaa atccttgcag acgataggta 27240
gacactgaac acgttaacga tagtatcaat aacgcaatca tgattttatg gtattaataa 27300
ttaaccttat ttttatgttc ggtataaaaa ttattgatgt ctacacatcc ttttgtaatt 27360
gacatctata tatccttttg tataatcaac tctaatcact ttaactttta cagttttccc 27420
taccagttta tccctatatt caacatatct atccatatgc atcttaacac tctctgccaa 27480
gatagcttca aagtgaggat agtcaaaaag ataaatatat agagcataat ccttctcgta 27540
tactctgccc tttattacat cacccgcatt gggcaacgaa taacaaaatg caagcatctt 27600
gttaacgggc tcgtaaattg ggataaaaat tatgttttta tatctatttt attcaagaga 27660
atattcagga atttcttttt ccggttgtat ctcatcgcag tatatatcat ttgtacattg 27720
tttcatattt tttaatagtc tacacctttt agtaggacta gtatcgtaca attcatagct 27780
gtattttgaa ttccaatcac gcataaaaat atcttccaat tgttgacgaa gacctaatcc 27840
atcatccggt gtaatattaa tagatgctcc acatgtatcc gtaaagtaat ttcctgtcca 27900
atttgaggta cctatatacg ccgttttatc ggttaccata tatttggcat ggtttaccct 27960
agaatacgga atgggaggat cagcatctgg tacaataaat agctttactt ctatatttat 28020
gtttttagat tttagcatag cgatagatct taaaaagttt ctcatgataa acgaagatcg 28080
ttgccagcaa ctaatcaata gcttaactga cacttgtctg tctatagcgg ctcttcttaa 28140
ttcatcttct atataaggcc aaaacaaaat attgcctgcc ttcgaataaa taatagggat 28200
aaagttcata acagatacat aaacgaattt actcgcattt ctgatacatg acaataaagc 28260
ggttaaatca ttggttcttt ccatagtaca tagttgttgc ggtgcagaag caataaatac 28320
agagtgtgga acgccgctta cgttaatact aagaggatga tctgtattat aatacgacgg 28380
ataaaagttt ttccaattat atggtagatt gttaactcca agataccagt atacctcaaa 28440
aatttgagtg agatccgctg ccaagttcct attattgaag atcgcaatac ccaattcttt 28500
gacctgagtt agtgatctcc aatccatgtt agcgcttcct aaataaatat gtgtattatc 28560
agatatccaa aattttgtat gaagaactcc tcctaggata tttgtaatat ctatgtatcg 28620
tacttcaact ccggccattt gtagtctttc aacatccttt aatggtttgt tagatttatt 28680
gacggctact ctaactcgta ctcctctttt gggtaattgt acaatcttgt ttaatattat 28740
cgtgccgaaa ttcgtaccca cttcatccga taaactccaa taaaaagatg atatatctag 28800
tgtttttgtg gtattggata gaatttccct ccacatgtta aatgtagaca aatatacttt 28860
atcaaattgc atacctatag gaatagtctc tgtaatcact gcgattgtat tatccggatt 28920
cattttattt gttaaaagaa taatcctata tcacttcact ctattaaaaa tccaagtttc 28980
tatttctttc atgactgatt ttttaacttc atccgtttcc ttatgaagat gatgtttggc 29040
accttcataa atttttattt ctctattaca atttgcatgt tgcatgaaat aatatgcacc 29100
taaaacatcg ctaatcttat tgtttgttcc ctggagtatg agagtcgggg ggtgttaatc 29160
ttggaaatta tttttctaac cttgttggta gccttcaaga cctgactagc aaatccagcc 29220
ttaatttttt catgattgat taatgggtcg tattggtatt tataaacttt atccatatct 29280
ctagatactg attctggaca tagctttccg actggcgcat ttagtgtgat ggttcccata 29340
agtttggcag ctagcagatt cagttttgaa acagcatctg cattaactag aggagacatt 29400
agaatcattg ctgtaaacaa gtttggatta tcgtaagagg ctagctccca tggaatgacc 29460
caataagtag atttaatagt taccacgtgc tgtaccaaag tcatcaatca tcattttttc 29520
accattactt cttccatgtc caatatgatc atgtgagaat actaaaattc ctaacgatga 29580
tatgttttca gctagttcgt cataacgtcc agaatgttta ccagctccat gacttatgaa 29640
tactaatgcc ttaggatatg taataggttt ccaatatatg taatcattgt ccagattgaa 29700
catacagttt gcactcatga ttcacgttat ataactatca atattaacag ttcgtttgat 29760
gatcatatta tttttatgtt ttattgataa ttgtaaaaac atacaattaa atcaatatag 29820
aggaaggaga cggctactgt cttttgtgag atagtcatgg cgactaaatt agattatgag 29880
gatgctgttt tttactttgt ggatgatgat aaaatatgta gtcgcgactc catcatcgat 29940
ctaatagatg aatatattac gtggagaaat catgttatag tgtttaacaa agatattacc 30000
agttgtggaa gactgtacaa ggaattgatg aagttcgatg atgtcgctat acggtactat 30060
ggtattgata aaattaatga gattgtcgaa gctatgagcg aaggagacca ctacatcaat 30120
tttacaaaag tccatgatca ggaaagttta ttcgctacca taggaatatg tgctaaaatc 30180
actgaacatt ggggatacaa aaagatttca gaatctagat tccaatcatt gggaaacatt 30240
acagatctga tgaccgacga taatataaac atcttgatac tttttctaga aaaaaaattg 30300
aattgatgat ataggggtct tcataacgca taattattac gttagcattc tatatccgtg 30360
ttaaaaaaaa ttatcctatc atgtatttga gagttttata tgtagcaaac atgatagctg 30420
tgatgccaat aagctttaga tattcacgcg tgctagtgtt agggatggta ttatctggtg 30480
gtgaaatgtc cgttatataa tctacaaaat aatcatcgca tatagtatgc gatagtagag 30540
taaacatttt tatcgtttct actgggttca tacatcgtct acccaattcg gttataaatg 30600
aaattgtcgc caatcttaca cccaacccct tgttatccat tagtatagta ttaacttcgt 30660
tatttatgtc ataaactgta aatgattttg tagatgccat atcatacatg atattcatgt 30720
ccctattata atcattacta actttatcac aatatatgtt gataatatct atatatgatc 30780
tagtctttgt gggcaactgt ctatacaagt cgtctaaacg ttgtttactc atatagtatc 30840
gaacagccat cattacatgg tcccgttccg ttgatagata atcgagtatg ttagtggact 30900
tgtcaaatct atataccata ttttctggaa gtggatatac atagtcgtga tcaacattat 30960
tgctagcctc atcttctata tcctgtacta taccattatc tatatcatct acataatcta 31020
cgatattatt acacataaac atcgacaaca tactattgtt tattatctaa gtcctgttga 31080
tccaaaccct tgatctcctc tatttgtact atctagagat tgtacttctt ccagttctgg 31140
ataatatata cgttgataga ttagctgagc tattctatct ccagtattta cattaaacgt 31200
acattttcca ttattaataa gaatgactcc tatgtttccc ctataatctt cgtctattac 31260
accgcctcct atatcaatgc cttttaggga cagaccagac ctaggagcta ttctaccata 31320
gcagaactta ggcatggaca tactaatatc tgtcttaatt aactgtcgtt ctcctggagg 31380
gatagtataa tcgtaagcgc tatataaatc atatccggcg gcgtaaggtg attgcctagt 31440
aggagattta gctctgttag tttccttaac aaatctaact ggtgagttaa tattcatgtt 31500
gaacataaaa ctaatatttt atttcaaaat tatttaccat cccatatatt ccatgaataa 31560
gtgtgatgat tgtacacttc tatagtatct atatacgatt cacgataaaa tcctcctatc 31620
aatagcagtt tattatccac tatgatcaat tctggattat ccctcggata aataggatca 31680
tctatcagag tccatgtatt gctggattca caataaaatt ccgcatttct accaaccaag 31740
aataaccttc taccgaacac taacgcgcat gatttataat gaggataata agtggatggt 31800
ccaaactgcc actgatcatg attgggtagc aaatattctg tagttgtatc agtttcagaa 31860
tgtcctccca ttacgtatat aacattgttt atggatgcca ctgctggatt acatctaggt 31920
ttcagaagac tcggcatatt aacccaagca gcatccccgt ggaaccaacg ctcaacagat 31980
gtgggatttg gtagacctcc tactacgtat aatttattgt tagcgggtat cccgctagca 32040
tacagtctgg ggctattcat cggaggaatt ggaatccaat tgtttgatat ataatttacc 32100
gctatagcat tgttatgtat ttcattgttc atccatccac cgatgagata tactacttct 32160
ccaacatgag tacttgtaca catatggaat atatctataa tttgatccat gttcatagga 32220
tactctatga atggatactt gtatgatttg cgtggttgtt tatcacaatg aaatattttg 32280
gtacagtcta gtatccattt tacattattt atacctctgg gagaaagata atttgacctg 32340
attacatttt tgataaggag tagcagattt cctaatttat ttcttcgctt tatataccac 32400
ttaatgacaa aatcaactac ataatcctca tctggaacat ttagttcatc gctttctaga 32460
ataagtttca tagatagata atcaaaattg tctatgatgt catcttccag ttccaaaaag 32520
tgtttggcaa taaagttttt agtatgacat aagagattgg atagtccgta ttctataccc 32580
atcatgtaac actcgacaca atattccttt ctaaaatctc gtaagataaa gtttatacaa 32640
gtgtagatga taaattctac agaggttaat atagaagcac gtaataaatt gacgacgtta 32700
tgactatcta tatatacctt tccagtatac gagtaaataa ctatagaagt taaactgtga 32760
atgtcaaggt ctagacaaac ccttgtaact ggatctttat ttttcgtgta tttttgacgt 32820
aaatgtgtgc gaaagtaagg agataacttt ttcaatatcg tagaattgac tattatattg 32880
ccacctatag catcaataat tgttttgaat ttcttagtca tagacaatgc taatatattc 32940
ttacagtaca cagtattaac aaatatcggc atttatgttt ctttaaaagt caacatctaa 33000
agaaaaatga ttatcttctt gagacataac tcccattttt tggtattcac ccacacgttt 33060
ttcgaaaaaa ttagtttttc cttccaatga tatattttcc atgaaatcaa acggattggt 33120
aacattataa atttttttaa atcccaattc agaaatcaat ctatccgcga cgaattctat 33180
atatgttttc atcatttcac aattcattcc tataagttta actggaagag ccgcagtaag 33240
aaattcttgt tcaatggata ccgcatctgt tataatagat ctaacggttt cttcactcgg 33300
tggatgcaat aaatgtttaa acatcaaaca tgcgaaatcg cagtgcagac cctcgtctct 33360
actaattagt tcgttggaaa acgtgagtcc gggcattagg ccacgctttt taagccaaaa 33420
tatggaagcg aatgatccag aaaagaagat tccttctact gcagcaaagg caataagtct 33480
ctctccataa ccggcgctgt catgtatcca cttttgagcc caatcggcct tcttttttac 33540
acaaggcatc gtttctatgg cattaaagag atagtttttt tcattactat ctttaacata 33600
agtatcgatc aaaagactat acatttccga atgaatgttt tcaatggcca tctgaaatcc 33660
gtagaaacat ctagcctcgg taatctgtac ttctgtacaa aatcgttccg ccaaattttc 33720
attcactatt ccgtcactgg ctgcaaaaaa cgccaataca tgttttataa aatatttttc 33780
gtctggtgtt agtttattcc aatcattgat atctttagat atatctactt cttccactgt 33840
ccaaaatgat gcctctgcct ttttatacat gttccagatg tcataatatt ggattgggaa 33900
aataacaaat ctatttggat ttggtgcaag gatgggttcc ataactaaat taacaataac 33960
aataaatttt ttttcagtta tctatatgcc tgtacttgga tcttttgtac atcgatatcg 34020
ccgcaatcac tacaataatt acaagtatta ttgatagcat tgttattagt actatcataa 34080
ttaaattatc gacattcatg ggtgctgaat aatcgttatt atcatcatta tcattttgta 34140
attgtgacat catactagat aaatcgtttg cgagattgtt gtgggaagcg ggcatggagg 34200
atgaattatc gttattatta tttaacgcct cccattcgga ttcacaaatg ttacgcacat 34260
tcaacatttt atggaaacta taattttgtg aaaacagata acaagaaaac tcgtcatcgt 34320
tcaaattttt aacgatagta aaccgattaa acgtcgagct aatttctaac gctagcgact 34380
ctgttggata tgggtttcca gatatatatc ttttcagttc ccctacgtat ctataatcat 34440
ctgtaggaaa tggaagatat ttccatttat ctactgttcc taatatcata tgtggtggtg 34500
tagtagaacc attaagcgcg aaagatgtta tttcgcatcg tattttaact tcgcaataat 34560
ttctggttag ataacgcact ctaccagtca agtcaatgat attagccttt acagatatat 34620
tcatagtagt tgtaacgatg actccatctt ttagatgcga tactcctttg tatgtaccag 34680
aatcttcgta ccgcaaactc gatatattta aacaagttaa tgagatatta acgcgtttta 34740
tgaatgatga tatataacca gaagttttat cctcggtggc tagcgctata accttatcat 34800
tataatacca actagtgtga ttaatatgtg acacgttagt gtgggtacaa atatgtacat 34860
tatcgtctac gtcgtattcg atacatccgc atacagccaa caaatataaa atgacaaata 34920
ctctaacgcc gttcgtaccc atcttgatgc ggtttaataa atgttttgat ttcaatttat 34980
tgtaaaaaaa gattcggttt tatactgttc gatattctca ttgcttatat tttcatctat 35040
catctccaca cagtcaaatc cgtggttagc atgcacctca tcaaccggta aaagactatc 35100
ggactcttct atcattataa ctctagaata tttaatttgg tcattattaa tcaagtcaat 35160
tatcttattt ttaacaaacg tgagtatttt actcattttt tataaaaact tttagaaata 35220
tacagactct atcgtgtgtc tatatcttct ttttatatcc aatgtattta tgtctgattt 35280
ttcttcattt atcatatata atggtccaaa ttctacacgt gcttcggatt catccagatc 35340
attaaggttc ttataattgt aacatccttc tcttccctct tctacatctt ccttcttatt 35400
cttattctta gcgtcacaga atctaccaca gcaggatccc atgacgagcg tcatattaaa 35460
ctaatccatt ttcaattata atatacgatt agtaatgacc attaaaataa aaaatattct 35520
tcataaccgg caagaaagtg aaaagttcac attgaaacta tgtcagtagt atacatcatg 35580
aaatgatgat atatatatac tctattttgg tggaggatta tatgatataa ttcgtggata 35640
atcattctta agacacattt cttcattcgt aaatcttttc acgttaaatg agtgtccata 35700
ttttgcaatt tcttcatatg atggcggtgt acgtggacga agctgctcct gttcttgttg 35760
tagtcgccga ctgtcgtgtt tgcgtttaga tccctccatt atcgcgattg cgtagatgga 35820
gtactattat ataccttgta attaaatttt tttattaatt aaacgtataa aaacgttccg 35880
tatctgtatt taagagccag atttcgtcta atagaacaaa tagctacagt aaaaataact 35940
agaataattg ctacacccac tagaaaccac ggatcgtaat acggcaatcg gttttcgata 36000
ataggtggaa cgtatatttt atttaaggac ttaacaattg tctgtaaacc acaatttgct 36060
tccgcggatc ctgtattaac tatctgtaaa agcatatgtt gaccgggcgg agccgaacat 36120
tctccgatat ctaatttctg tatatctata atattattaa cctccgcata cgcattacag 36180
ttcttttcta gcttggatac cgcactaggt acatcgtcta gatctattcc tatttcttca 36240
gcgatagctc ttctatcctt ttccggaagc aatgaaatca cttcaataaa tgattcaacc 36300
atgagtgtga aactaagtcg agaattactc atgcatttgt tagttattcg gagcgcgcaa 36360
tttttaaact gtcctataac ctctcctata tgaatagcac aagtgacatt agtagggata 36420
gaatgttgag ctaatttttg taaataacta tctataaaaa gattatacaa agttttaaac 36480
tctttagttt ccgccattta tccagtctga gaaaatgtct ctcataataa atttttccaa 36540
gaaactaatt gggtgaagaa tggaaacctt taatctatat ttatcacagt ctgttttggt 36600
acacatgatg aattcttcta atgctgtact aaattcgata tctttttcga tttctggata 36660
tgtttttaat aaagtatgaa caaagaaatg gaaatcgtaa taccagttat gttcaacttt 36720
gaaattgttt tttattttct tgttaatgat tccagccact tgggaaaagt caaagtcgtt 36780
taatgccgat ttaatacgtt cattaaaaac aaacttttta tcctttagat gaattattat 36840
tggttcattg gaatcaaaaa gtaagatatt atcgggttta agatctgcgt gtaaaaagtt 36900
gtcgcaacag ggtagttcgt agattttaat gtataacaga gccatctgta aaaagataaa 36960
ctttatgtat tgtaccaaag atttaaatcc taatttgata gctaactcgg tatctacttt 37020
atctgccgaa tacagtgcta ggggaaaaat tataatattt cctctttcgt attcgtagtt 37080
agttctcttt tcatgttcga aaaagtgaaa catgcggtta aaatagttta taacattaat 37140
attactgtta ataactgccg gataaaagtg ggatagtaat ttcacgaatt tgatactgtc 37200
ctttctctcg ttaaacgcct ttaaaaaaac tttagaagaa tatctcaatg agagttcctg 37260
accatccata gtttgtatca ataatagcaa catatgaaga acccgtttat acagagtatg 37320
taaaaatgtt aatttatagt ttaatcccat ggcccacgca cacacgatta attttttttc 37380
atctcccttt agattgttgt atagaaattt gggtactgtg aactccgccg tagtttccat 37440
gggactatat aattttgtgg cctcgaatac aaattttact acatagttat ctatcttaaa 37500
gactatacca tatcctcctg tagatatgtg ataaaaatcg tcgtttatag gataaaatcg 37560
tttatccttt tgttggaaaa aggatgaatt aatgtaatca ttctcttcta tctttagtag 37620
tgtttcctta ttaaaattct taaaataatt taacaatcta actgacggag cccaattttg 37680
gtgtaaatct aattgggaca ttatgttgtt aaaatacaaa cagtctccta atataacagt 37740
atctgataat ctatggggag acatccattg atattcaggg gatgaatcat tggcaacacc 37800
catttattgt acaaaaagcc ccaatttaca aacgaaagtc caggtttgat agagacaaac 37860
aattaactat tttgtctctg tttttaattt ctttggtaat gaaattattc acaatatcag 37920
tatcttcttt atctaccaga gattttacta acttgataac cttggctgtc tcattcaata 37980
gggtagtaat atttgtatgt gtgatattga tatctttttg aattgtttct tttagaagtg 38040
attctttgat ggtgccagca tacgaattac aataatgcag aaactcagtt aacatgcagg 38100
aattatagta agccaattcc aattgttgcc tgtattgtat tagagtatta atatgcgcaa 38160
tggtgtcctt gcgtttctct gatagaatgc gagcagcgat tttggcgtta tcatttgacg 38220
atatttctgg aatgacgaat cctgtttcta ctaacttttt ggtaggacaa agtgaaacaa 38280
tcaagaagat agcttctcct cctatttgtg gaagaaattg aactcctcta gatgatctac 38340
tgacgatagt atctccttga cagatattgg accgaattac agaagtacct ggaatgtaaa 38400
gccctgaaac cccctcattt tttaagcaga ttgttgccgt aaatcctgca ctgtgaccaa 38460
gatagagagc tcctttggtg aatccatctc tatgtttcag tttaaccaag aaacagtcag 38520
ctggtctaaa atttccatct ctatctaata cagcatctaa cttgatgtca ggaactatga 38580
ccggtttaat gttatatgta acattgagta aatccttaag ttcataatca tcactgtcat 38640
cagttatgta cgatccaaac aatgtttcta ctggcatagt ggatacgaag atgctatcca 38700
tcagaatgtt tccctgatta gtattttcta tatagctatt cttctttaaa cgattttcca 38760
aatcagtaac tatgttcatt tttttaggag taggacgcct agccagtatg gaagaggatt 38820
ttctagatcc tctcttcaac atctttgatc tcgatggaat gcaaaacccc atagtgaaac 38880
aaccaacgat aaaaataata ttgtttttca ctttttataa ttttaccatc tgactcatgg 38940
attcattaat atctttataa gagctactaa cgtataattc tttataactg aactgagata 39000
tatacaccgg atctatggtt tccataattg agtaaatgaa tgctcggcaa taactaatgg 39060
caaatgtata gaacaacgaa attatactag agttgttaaa gttaatattt tctatgagct 39120
gttccaataa attatttgtt gtaactgcgt tcaagtcata aatcatcttg atactatcca 39180
gtaaaccgtg tttaagttct ggaatattat catcccattg taaagcccct aattcgacta 39240
tcgaatatcc tgctctgata gcagtttcaa tatcgacgga cgtcaatact gtaataaagg 39300
tggtagtatt gtcatcatcg tgataaacta cgggaatatg gtcgttagta ggtacggtga 39360
ctttacacaa cgcgatatat aactttcctt ttgtaccatt tttaacgtag ttgggacgtc 39420
ctgcagggta ttgttttgaa gaaatgatat cgagaacaga tttgatacga tatttgttgg 39480
attcctgatt attcactata atataatcta gacagataga tgattcgata aatagagaag 39540
gtatatcgtt ggtaggataa tacatcccca ttccagtatt ctcggatact ctattgatga 39600
cactagttaa gaacatgtct tctattctag aaaacgaaaa catcctacat ggactcatta 39660
aaacttctaa cgctcctgat tgtgtctcga atgcctcgta caaggatttc aaggatgcca 39720
tagattcttt gaccaacgat ttagaattgc gtttagcatc tgattttttt attaaatcga 39780
atggtcggct ctctggtttg ctaccccaat gataacaata gtcttgtaaa gataaaccgc 39840
aagaaaattt atacgcatcc atccaaataa ccctagcacc atcggatgat attaatgtat 39900
tattatagat tttccatcca caattattgg gccagtatac tgttagcaac ggtatatcga 39960
atagattact catgtaacct actagaatga tagttcgtgt actagtcata atatctttaa 40020
tccaatctaa gaaatttaaa attagatttt ttacactgtt aaagttaaca aaggtattac 40080
ccggatacgt ggatatcata tatggcattg gtccattatc agtaatagct ccataaactg 40140
atacggcgat ggtttttata tgtgtttgat ctaacgagga agaaattcgc gcccacaatt 40200
catctctaga tatgtattta atatcaaacg gtaacacatc aatttcggga cgcgtatatg 40260
tttctaaatt tttaatccaa atataatgat gacctatatg ccctattatc atactgtcaa 40320
ctatagtaca cctagagaac ttacgataca tctgtttcct ataatcgtta aattttacaa 40380
atctataaca tgctaaacct tttgacgaca gccattcatt aatttctgat atggaatctg 40440
tattctcgat accgtattgt tctaaagcca gtgctatatc tccctgttcg tgggaacgct 40500
ttcgtataat atcgatcaac ggataatctg aagtttttgg agaataatat gactcatgat 40560
ctatttcgtc cataaacaat ctagacatag gaattggagg cgatgatctt aattttgtgc 40620
aatgagtcgt caatcctata acttctaatc ttgtaatatt catcatcgac ataatactat 40680
ctatgttatc atcgtatatt agtataccac ggccttcttc atttcgtgcc aaaataatat 40740
acagtcttaa ataattacgc aatatctcaa tagtttcata attgttagct gttttcatca 40800
agatttgtac cctgtttaac atgatggcgt tctatacgtc tctattttct tttttttaaa 40860
tttttaacga tttactgtgg ctagataccc aatctctctc aaatattttt ttagcctcgc 40920
ttacaagctg tttatctata ctattaaaac tgacgaatcc gtgattttgg taatgggttc 40980
cgtcgaaatt tgccgaagtg atatgaacat attcgtcgtc gactatcaac aattttgtat 41040
tattctgaat agtgaaaacc ttcacagata gatcattttg aacacacaac gcgtctagac 41100
ttctggcggt tgccatagaa tatacgtcgt tcttatccca attaccaact agaagtctga 41160
tcttaactcc tctattaatg gctgcttcta taatggagtt gtaaatgtcg ggccaatagt 41220
agctattacc gtcgacacgt gtagtgggaa ctatggccaa atgttcaata tctatactag 41280
tcttagccga cttgagttta tcaataacta catcggtatc tagatctcta gaatatccca 41340
ataggtgttc cggagaatca gtaaagaaca ctccacctat aggattctta atatgatacg 41400
cagtgctaac tggcaaacaa caagccgcag agcataaatt caaccatgaa ttttttgcgc 41460
tattaaaggc tttaaaagta tcaaatcttc tacgaagatc tgtggccagc gggggataat 41520
cagaatatac acctaacgtt ttaatcgtat gtatagatcc tccagtaaat gacgcgtttc 41580
ctacataaca tctttcatca tctgacaccc aaaaacaacc gagtagtagt cccacattat 41640
tttttttatc tatattaacg gttataaaat ttatatccgg gcagtgactt tgtagctctc 41700
ccagatttct tttccctcgt tcatctagca aaactattat tttaatccct ttttcagatg 41760
cctcttttag tttatcaaaa ataagcgctc ccctagtcgt actcagagga ttacaacaaa 41820
aagatgctat gtatatatat ttcttagcta gagtgataat ttcgttaaaa cattcaaatg 41880
ttgttaaatg atcggatcta aaatccatat tttctggtag tgtttctacc agcctacatt 41940
ttgctcccgc aggtaccgat gcaaatggcc acatttagtt aacataaaaa cttatacatc 42000
ctgttctatc aacgattcta gaatatcatc ggctatatcg ctaaaatttt catcaaagtc 42060
gacatcacaa cctaactcag tcaatatatt aagaagttcc atgatgtcat cttcgtctat 42120
ttctatatcc gtatccattg tagattgttg accgattatc gagtttaaat cattactaat 42180
actcaatcct tcagaataca atctgtgttt cattgtaaat ttataggcgg tgtatttaag 42240
ttggtagatt ttcaattatg tatcaatata gcaacagtag ttcttgctcc tccttgattc 42300
tagcatcctc ttcattattt tcttctacgt acataagcat gtccaatacg ttagacaaca 42360
caccgacgat ggcggccgcc acagacacga atatgactag accgatgacc atttaaaaac 42420
ccctctctag ctttcactta aactgtatcg attattcttt tagaacatgt ataatataaa 42480
aacattattc tatttcgaat ttaggcttcc aaaaattttt catccgtaaa ccgataataa 42540
tatatataga cttgttaata gtcggaataa atagattaat gcttaaacta tcatcatctc 42600
cacgattaga gatacaatat ttacattttt tttgctgttt cgaaacttta tcaatacacg 42660
ttaatacaaa cccaggaagg agatattgaa actgaggctg ttgaaaatga aacggtgaat 42720
acaataattc agataatgta aaatcatgat tccgtattct gatgatatta gaactgctaa 42780
tggatgtcga tggtatgtat ctaggagtat ctattttaac aaagcatcga tttgctaata 42840
tacaattatc cttttgatta attgttattt tattcatatt cttaaaaggt ttcatattta 42900
tcaattcttc tacattaaaa atttccattt ttaatttatg tagcccccgc aatactcctc 42960
attacgtttc attttttgtc tataatatcc attttgttca tctcggtaca tagattatcc 43020
aattgagaag cgcatttagt agttttgtac attttaagtt tattgacgaa tcgtcgaaaa 43080
ctagttatag ttaacatttt attatttgat accctgatat taatacccct gccgttacta 43140
ttatttataa ctgatgtaat ccacgtaaca ttagaattaa ttatcgatag taatgcatcg 43200
acgcttccaa aattgtctat tataaactca ccgataattt ttttattgca tgttttcata 43260
ttcattagga ttatcaaatc tttaatctta ctacgattgt atgcgttgat attgcaagac 43320
gtcattctaa aagacggagg atctccatca aatgccagac aatcacgtac aaagtacatg 43380
gaaataggtt ttgttctatt gcgcatcata gatttatata gaacacccgt agaaatacta 43440
atttgtttta ctctataaaa tactaatgca tctatttcat cgttttgtat aacgtctttc 43500
caagtgtcaa attccaaatt tttttcattg atagtaccaa attcttctat ctctttaact 43560
acttgcatag ataggtaatt acagtgatgc ctacatgccg ttttttgaaa ctgaatagat 43620
gcgtctagaa gcgatgctac gctagtcaca atcaccactt tcatatttag aatatatgta 43680
tgtaaaaata tagtagaatt tcattttgtt tttttctatg ctataaatga attctcattt 43740
tgcatctgct catactccgt tttatatcaa taccaaagaa ggaagatatc tggttctaaa 43800
agccgttaaa gtatgcgatg ttagaactgt agaatgcgaa ggaagtaaag cttcctgcgt 43860
actcaaagta gataaaccct catcgcccgc gtgtgagaga agaccttcgt ccccgtccag 43920
atgcgagaga atgaataacc ctggaaaaca agttccgttt atgaggacgg acatgctaca 43980
aaatatgttc gcggctaatc gcgacaacgt ggcgtcgaga cttttgaact aaaatacaat 44040
tatatccttt tcgatattaa taaatccgtg tcgtccaggt tttttatctc tttcagtatg 44100
tgaatagata ggtattttat ctctattcat catcgaattt aagagatccg ataaacattg 44160
tttgtattct ccagatgtca gcatctgata caacaatata tgtgcacata aacctctggc 44220
acttatttca tgtaccttcc ccttatcact aaggagaata gtatttgaga aatatgtata 44280
catgatatta tcatgaatta gatatacaga atttgtaaca ctctcgaaat cacacgatgt 44340
gtcggcgtta agatctaata tatcactcga taacacattt tcatctagat acactagaca 44400
ttttttaaag ctaaaatagt ctttagtagt gacagtaact atgcgattat tttcatcgat 44460
gatacatttc atcggcatat tattacgctt accatcaaag actataccat gtgtatatct 44520
aacgtattct agcatggttg ccatacgcgc attaaacttt tcaggatctt tggatagatc 44580
ttccaatcta tctatttgag aaaacatttt tatcatgttc aatagttgaa acgtcggatc 44640
cactatatag atattatcta taaagatttt aggaactacg ttcatggtat cctggcgaat 44700
attaaaacta tcaatgatat gattatcgtt ttcatctttt atcaccatat agtttctaag 44760
atatgggatt ttacttaata taatattatt tcccgtgata aattttatta gaaaggccaa 44820
atctataaga aaagttctag aattagtctg aagaatatct atatcgccgt accgtatatt 44880
tggattaatt agatatagag aatatgatcc gtaacatata caacttttat tatggcgtct 44940
aagatattct tccatcaact tattaacatt tttgactagg gaagatacat tatgacgtcc 45000
cattactttt gccttgtcta ttactgcgac gttcatagaa tttagcatat ctcttgccaa 45060
ttcttccatt gatgttacat tataagaaat tttagatgaa attacatttg gagctttaat 45120
agtaagaact cctaatatgt ccgtgtatgt ggtcactaat acagattgta gttctataat 45180
cgtaaataat ttacctatat tatatgtttg agtctgttta gaaaagtagc taagtatacg 45240
atcttttatt tctgatgcag atgtattaac atcggaaaaa aatctttttt tattcttttt 45300
tactaaagat acaaatatgt ctttgttaaa aacagttatt ttttgaatat ttctagcttg 45360
taattttaac atatgatatt cgttcacact aggtactctg cctaaatagg tttctataat 45420
ctttaatgta atattaggaa gagtattctg atcaggattc ctattcattt tgaggattta 45480
aaactctgat tattgtctaa tatggtctct acgcaaactt tttcacagag cgatagagtt 45540
tttgataact cgtttttctt aagaaatata aaactactgt ctccagagct cgctctatct 45600
tttattttat ttaattcgat acaaactcct gatactggtt cagaaagtaa ttcattaatt 45660
ttcagtcctt tatagaagat atttaatata gataatacaa aattttcagt tcttgatatc 45720
gatctgattg atcctagaac tagatatatt aataacgtgc tcattaggca gtttatggca 45780
gcttgataat tagatatagt atattccagt tcatatttat tagataccgc attgcccaga 45840
ttttgatatt ctatgaattc ctctgaaaat aaatccaaaa taactaaaca ttctattttt 45900
tgtggattag tgtactctct tccctctatc atgttcacta ctggtgtcca cgatgataaa 45960
tatctagagg gaatataata tagtccatag gatgccaatc tagcaatgtc gaataactgt 46020
aatttgattc ttcgttcttc attatgaatt gattcttgag gtataaacct aacacaaatt 46080
atattattag acttttcgta tgtaatgtct ttcatgttat aagtttttaa tcctggaata 46140
gaatctattt taatgaggct tttaaacgca gagttctcca acgagtcaaa gcataatact 46200
ctgttgtttt tcttatatac gatgttacga ttttcttctt tgaatggaat aggtttttga 46260
attagtttat aattacaaca taatagataa ggaagtgtgc aaatagtacg cggaaaaaac 46320
ataatagctc ccctgttttc atccatggtt ttaagtaaat gatcactggc ttctttagtc 46380
aatggatatt cgaacattaa ccgtttcatc atcattggac agaatccata tttcttaatg 46440
taaagagtga tcaaatcatt gtgtttattg taccatcttg ttgtaaatgt gtattcggtt 46500
atcggatctg ctcctttttc tattaaagta tcgatgtcga tctcgtctaa gaattcaact 46560
atatcgacat atttcatttg tatacacata accattacta acgtagaatg tataggaaga 46620
gatgtaacgg gaacagggtt tgttgattcg caaactattc taatacataa ttcttctgtt 46680
aatacgtctt gcacgtaatc tattatagat gccaagatat ctatataatt attttgtaag 46740
atgatgttaa ctatgtgatc tatataagta gtgtaataat tcatgtattt cgatatatgt 46800
tccaactctg tctttgtgat gtctagtttc gtaatatcta tagcatcctc aaaaaatata 46860
ttcgcatata ttcccaagtc ttcagttcta tcttctaaaa aatcttcaac gtatggaata 46920
taataatcta ttttacctct tctgatatca ttaatgatat agtttttgac actatcttct 46980
gtcaattgat tcttattcac tatatctaag aaacggatag cgtccctagg acgaactact 47040
gccattaata tctctattat agcttctgga cataattcat ctattatacc agaattaatg 47100
ggaactattc cgtatctatc taacatagtt ttaagaaagt cagaatctaa gacctgatgt 47160
tcatatattg gttcatacat gaaatgatct ctattgatga tagtgactat ttcattctct 47220
gaaaattggt aactcattct atatatgctt tccttgttga tgaaggatag aatatactca 47280
atagaatttg taccaacaaa ctgttctctt atgaatcgta tatcatcatc tgaaataatc 47340
atgtaaggca tacatttaac aattagagac ttgtctcctg ttatcaatat actattcttg 47400
tgataattta tgtgtgaggc aaatttgtcc acgttcttta attttgttat agtagatatc 47460
aaatccaatg gagctacagt tcttggctta aacagatata gtttttctgg aacgaattct 47520
acaacattat tataaaggac tttgggtaga taagtgggat gaaatcctat tttaattaat 47580
gcgatagcct tgtcctcgtg cagatatcca aacgcttttg tgatagtatg gcattcattg 47640
tctagaaacg ctctacgaat atctgtgaca gatatcatct ttagagaata tactagtcgc 47700
gttaatagta ctacaatttg tattttttaa tctatctcaa taaaaaaatt aatatgtatg 47760
attcaatgta taactaaact actaactgtt attgataact agaatcagaa tctaatgatg 47820
acgtaaccaa gaagtttatc tactgccaat ttagctgcat tatttttagc atctcgttta 47880
gattttccat ctgccttatc gaatactctt ccgtcgatgt ctacacaggc ataaaatgta 47940
ggagagttac taggccccac tgattcaata cgaaaagacc aatctctcct agtaatttgg 48000
cagtactcat taataacggt gacagggtta gcacctttcc aatcaataat ttttttagcc 48060
ggaataacat catcaaaaga cttatgatcc tctctcattg atttttcgcg ggatacatca 48120
tctattatga cgtcagccat agcatcagca tccggcttat ccgcctccgt tgtcataaac 48180
caacgaggag gaatatcgtc ggagctgtac accatagcac tacgttgaag atcgtacaga 48240
gctttattaa cttctcgctt ctccatatta agttgtctag ttagttgtgc agcagtagct 48300
ccttcgattc caatggtttt aatagcctca cacacaatct ctgcgttaga acgctcgtcg 48360
atatagattt tagacatttt tagagagaac taacgcaatc agtaataaaa ctaatttatt 48420
ttatcatttt ttttattcat catcctctgg tggttcgtcg tttctatcga atgtagctct 48480
gattaacccg tcatctatag gtgatgctgg ttctggagat tctggaggag atggattatt 48540
atctggaaga atctctgtta tttccttgtt ttcatgtatc gattgcgttg taacattaag 48600
attgcgaaat gctctaaatt tgggaggctt aaagtgttgt ttgcaatctc tacacgcgtg 48660
tctaactagt ggaggttcgt cagcggctct agtttgaatc atcatcggcg tagtattcct 48720
acttttacag ttaggacacg gtgtattgta tttctcgtcg agaacgttaa aataatcgtt 48780
gtaactcaca tcctttattt tatctatatt gtattctact cctttcttaa tgcattttat 48840
accgaataag agatagcgaa ggaattcttt ttcggtgccg ctagtaccct taatcatatc 48900
acatagtgtt ttatattcca aatttgtggc aatagacggt ttatttctat acgatagttt 48960
gtttctggaa tcctttgagt attctatacc aatattattc tttgattcga atttagtttc 49020
ttcgatatta gattttgtat tacctatatt cttgatgtag tactttgatg atttttccat 49080
ggcccattct attaagtctt ccaagttggc atcatccaca tattgtgata gtaattctcg 49140
gatatcagta gcggttaccg ccattgatgt ttgttcattg gatgagtaac tactaatgta 49200
tacattttcc atttataaca cttatgtatt aactttgttc atttatattt tttcattatt 49260
atgttgatat taacaaaagt gaatatatat atgttaataa ttgtattgtg gttatacggc 49320
tacaatttta taattagtga aagtcagtgt ccgatgatca atgacgatag ctttactctg 49380
aaaagaaagt atcaaatcga tagtgcggag tcaacaataa aaatggataa gaagaggaca 49440
aagtttcaga atagagccaa aatggtaaaa gaaataaatc agacaataag agcagcacaa 49500
actcattacg agacattgaa actaggatac ataaaattta agagaatgat taggactact 49560
actctagaag atatagcacc atctattcca aataatcaga aaacttataa actattctcg 49620
gacatttcag ccatcggcaa agcatcacgg aatccaagta agatggtata tgctctgctg 49680
ctttacatgt ttcccaattt gtttggagat gatcatagat tcattcgtta tagaatgcat 49740
ccaatgagta aaatcaaaca caagatcttc tctcctttca aacttaatct tattagaata 49800
ttagtggaag aaagattcta taataatgaa tgcagatcta ataaatggag aataattgga 49860
acacaagttg ataaaatgtt gatagctgaa tctgataaat atacaataga tgcaaggtat 49920
aacctaaaac ccatgtatag aatcaaggga aaatctgaag aagataccct ctttatcaaa 49980
cagatggtag aacaatgtgt gacatcccag gaattggtgg aaaaagtgtt gaagatactg 50040
tttagagatt tgttcaagag tggagaatac aaagcgtaca gatacgatga tgatgtagaa 50100
aatggattta ttggattgga tacactaaaa ttaaacattg ttcatgatat agttgaacca 50160
tgtatgcctg ttcgtaggcc agtggctaag atactgtgta aagaaatggt aaataaatac 50220
tttgagaatc cgctacatat tattggtaaa aatcttcaag agtgcattga ctttgttagt 50280
gaataggcat ttcatctttc tccaatacta attcaaattg ttaaattaat aatggatagt 50340
ataaatagtt attagtgata aaatagtaaa aataattatt agaataagag tgtagtatca 50400
tagataactc tcttctataa aaatggattt tattcgtaga aagtatctta tatacacagt 50460
agaaaataat atagattttt taaaggatga tacattaagt aaagtaaaca attttaccct 50520
caatcatgta ctagctctca agtatctagt tagcaatttt cctcaacatg ttattactaa 50580
ggatgtatta gctaatacca atttttttgt tttcatacat atggtacgat gttgtaaagt 50640
gtacgaagcg gttttacgac acgcatttga tgcacccacg ttgtacgtta aagcattgac 50700
taagaattat ttatcgttta gtaacacaat acaatcgtac aaggaaaccg tgcataaact 50760
aacacaagat gaaaaatttt tagaggttgc caaatacatg gacgaattag gagaacttat 50820
aggcgtaaat tatgacttag ttcttaatcc attatttcac ggaggggaac ccatcaaaga 50880
tatggaaatc atttttttaa aactgtttaa gaaaacagac ttcaaagttg ttaaaaaatt 50940
aagtgttata agattactta tttgggctta cctaagcaag aaagatacag gcatagagtt 51000
tgcggataat gatagacaag atatatatac tctatttcaa caaactggta gaatcgtcca 51060
tagcaatcta acagaaacgt ttagagatta tatctttccc ggagataaga ctagctattg 51120
ggtgtggtta aacgaaagta tagctaatga tgcggatatt gttcttaata gacacgccat 51180
taccatgtat gataaaattc ttagttatat atactctgag ataaaacaag gacgcgttaa 51240
taaaaacatg cttaagttag tttatatctt tgagcctgaa aaagatatca gagaacttct 51300
gctagaaatc atatatgata ttcctggaga tatcctatct attattgatg caaaaaacga 51360
cgattggaaa aaatatttta ttagttttta taaagctaat tttattaacg gtaatacatt 51420
tattagtgat agaacgttta acgaggactt attcagagtt gttgttcaaa tagatcccga 51480
atatttcgat aatgaacgaa ttatgtcttt attctctacg agtgctgcgg acattaaacg 51540
atttgatgag ttagatatta ataacagtta tatatctaat ataatttatg aggtgaacga 51600
tatcacatta gatacaatgg atgatatgaa gaagtgtcaa atctttaacg aggatacgtc 51660
gtattatgtt aaggaataca atacatacct gtttttgcac gagtcggatc ccatggtcat 51720
agagaacgga atactaaaga aactgtcatc tataaaatcc aagagtagac ggctgaactt 51780
gtttagcaaa aacattttaa aatattattt agacggacaa ttggctcgtc taggtcttgt 51840
gttagatgat tataaaggag acttgttagt taaaatgata aaccatctta agtctgtgga 51900
ggatgtatcc gcattcgttc gattttctac agataaaaac cctagtattc ttccatcgct 51960
aatcaaaact attttagcta gttataatat ttccatcatc gtcttatttc aaaggttttt 52020
aagagataat ctatatcatg tagaagaatt cttggataaa agcatccatc taaccaagac 52080
ggataagaaa tatatacttc aattgataag acacggtaga tcatagaaca gaccaaatat 52140
attattaata atttgtatat acatagatat aattatcaca tattaaaaat tcacacattt 52200
ttgataaatg ggaactgctg caacaattca gactcccacc aaattaatga ataaagaaaa 52260
tgcagaaatg attttggaaa aaattgttga tcatatagtt atgtatatta gtgacgaatc 52320
aagtgattca gaaaataatc ctgaatatat tgattttcgt aacagatacg aagactatag 52380
atctctcatt ataaaaagtg atcacgagtt tgtaaagcta tgtaaaaatc atgcagagaa 52440
aagttctcca gaaacgcaac aaatgattat caaacacata tacgaacaat atcttattcc 52500
agtatctgaa gtactattaa aacctataat gtccatgggt gacataatta catataacgg 52560
atgtaaagac aatgaatgga tgctagaaca actctctacc ctaaacttta acaatctccg 52620
cacatggaac tcatgtagca taggcaatgt aacgcgtctg ttttatacat tttttagtta 52680
tctgatgaaa gataaactaa atatataagt ataatcccat tctaatactt taacctgatg 52740
tattagcatc ttattagaat attaacctaa ctaaaagaca taacataaaa actcattaca 52800
tagttgataa aaagcggtag gatataaata ttatggctgc caccgttccg cgttttgacg 52860
acgtgtacaa aaatgcacaa agaagaattc tagatcaaga aacatttttt agtagaggtc 52920
taagtagacc gttaatgaaa aacacatatc tatttgataa ttacgcgtat ggatggatac 52980
cagaaactgc aatttggagt agtagatacg caaacttaga tgcaagtgac tattatccca 53040
tttcgttggg attacttaaa aagttcgagt ttctcatgtc tctatataaa ggtcctattc 53100
cagtatacga agaaaaagta aatactgaat tcattgctaa tggatcgttc tctggtagat 53160
acgtatcata tcttcgaaag ttttctgctc ttccaacaaa cgagtttatt agttttttgt 53220
tactgacttc cattccaatc tataatatct tgttctggtt taaaaatact cagtttgata 53280
ttactaaaca cacattattc agatacgtct atacagataa tgccaaacac ctggcgttgg 53340
ctaggtatat gcatcaaaca ggagactata agcctttgtt tagtcgtctc aaagagaatt 53400
atatatttac cggtcccgtt ccaataggta tcaaagatat aaatcaccct aatcttagta 53460
gagcaagaag tccatccgat tatgagacat tagctaatat tagtactata ttgtacttta 53520
ccaagtatga tccggtatta atgtttttat tgttttacgt acctgggtat tcaattacta 53580
caaaaattac tccagccgta gaatatctaa tggataaact gaatctaaca aagagcgacg 53640
tacaactgtt gtaaattatt ttatgcttcg taaaatgtag gttttgaacc aaacattctt 53700
tcaaagaatg agatgcataa aactttatta tccaatagat tgactatttc ggacgtcaat 53760
cgtttaaagt aaacttcgta aaatattctt tgatcactgc cgagtttaaa acttctatcg 53820
ataattgttt catatgtttt aatatttaca agttttttgg tccatggtac attagccgga 53880
caaatatatg caaaataata tcgttctcca agttctatag tttctggatt atttttatta 53940
tattcagtaa ccaaatacat attagggtta tctgcggatt tataatttga gtgatgcatt 54000
cgactcaaca taaataattc tagaggagac gatctactat caaattcgga tcgtaaatct 54060
gtttctaaag aacggagaat atctatacat acctgattag aattcatccg tccttcagac 54120
aacatctcag acagtctggt cttgtatgtc ttaatcatat tcttatgaaa cttggaaaca 54180
tctcttctag tttcactagt acctttatta attctctcag gtacagattt tgaattcgac 54240
gatgccgagt atttcatcgt tgtatatttc ttcttcgatt gcataatcag attcttatat 54300
accgcctcaa actctatttt aaaattatta aacaatactc tattattaat cagtcgttct 54360
aactcctttg ctatttctat ggacttatct acatcttgac tgtctatctc tgtaaacacg 54420
gagtcggtat ctccatacac gctacgaaaa cgaaatctgt aatctatagg caacgatgtt 54480
ttcacaatcg gattaatatc tctatcgtcc atataaaatg gattacttaa tggattggca 54540
aaccgtaaca taccgttaga taactctgct ccatttagta ccgattctag atacaagatc 54600
attctacgtc ctatggatgt gcaactctta gccgaagcgt atgagtatag agcactattt 54660
ctaaatccca tcagaccata tactgagttg gctactatct tgtacgtata ttgcatggaa 54720
tcatagatgg ccttttcagt tgaactggta gcctgtttta acatcttttt atatctggct 54780
ctctctgcca aaaatgttct taatagtcta ggaatggttc cttctatcga tctatcgaaa 54840
attgctattt cagagatgag gttcggtagt ctaggttcac aatgaaccgt aatatatcta 54900
ggaggtggat atttctgaag caagagctga ttatttattt cttcttccaa tctattggta 54960
ctaacaacga caccgactaa tgtttccgga gatagatttc caaagataca cacattagga 55020
tacagactgt tataatcaaa gattaataca ttattactaa acattttttg ttttggagca 55080
aataccttac cgccttcata aggaaacttt tgttttgttt ctgatctaac taagatagtt 55140
ttagtttcca acaatagctt taacagtgga cccttgatga ctgtactcgc tctatattcg 55200
aataccatgg attgaggaag cacatatgtt gacgcacccg cgtctgtttt tgtttctact 55260
ccataatact cccacaaata ctgacacaaa caagcatcat gaatacagta tctagccata 55320
tctaaagcta tgtttagatt ataatcctta tacatctgag ctaaatcaac gtcatccttt 55380
ccgaaagata atttatatgt atcattaggt aaagtaggac ataatagtac gactttaaat 55440
ccattttccc aaatatcttt acgaattact ttacatataa tatcctcatc aacagtcaca 55500
taattacctg tggttaaaac ctttgcaaat gcagcggctt tgcctttcgc gtccgtagta 55560
tcgtcaccga tgaacgtcat ttctctaact cctctattta atactttacc catgcaactg 55620
aacgcgttct tggatataga atccaatttg tacgaatcca atttttcaga tttttgaatg 55680
aatgaatata gatcgaaaaa tatagttcca ttattgttat taacgtgaaa cgtagtattg 55740
gccatgccgc ctactccctt atgactagac tgatttctct cataaataca gagatgtaca 55800
gcttcctttt tgtccggaga tctaaagata atcttctctc ctgttaataa ctctagacga 55860
ttagtaatat atctcagatc aaagttatgt ccgttaaagg taacgacata gtcgaacgtt 55920
agttccaaca attgtttagc tattcgtaac aaaactattt cagaacataa aactagttct 55980
cgttcgtaat ccatttccat tagtgactgt atcctcaaac atcctctatc gacggcttct 56040
tgtatttcct gttccgttaa catctcttca ttaatgagcg taaacaataa tcgtttacca 56100
cttaaatcga tataacagta acttgtatgc gagattgggt taataaatac agaaggaaac 56160
ttcttatcga agtgacactc tatatctaga aataagtacg atcttgggat atcgaatcta 56220
ggtatttttt tagcgaaaca gttacgtgga tcgtcacaat gataacatcc attgttaatc 56280
tttgtcaaat attgctcgtc caacgagtaa catccgtctg gagatatccc gttagaaata 56340
taaaaccaac taatattgag aaattcatcc atggtggcat tttgtatgct gcgtttcttt 56400
ggctcttcta tcaaccacat atctgcgacg gagcattttc tatctttaat atctagatta 56460
taacttattg tctcgtcaat gtctatagtt ctcatctttc ccaacggcct cgcattaaat 56520
ggaggaggag acaatgactg atatatttcg tccgtcacta cgtaataaaa gtaatgagga 56580
aatcgtataa atacggtctc accatttcga catctggatt tcagatataa aaatctgttt 56640
tcaccgtgac tttcaaacca attaatgcac cgaacatcca tttatagaat ttagaaatat 56700
attttcattt aaatgaatcc caaacattgg ggaagagccg tatggaccat tatttttata 56760
gtactttcgc aagcgggttt agacggcaac atagaagcgt gtaaacgaaa actatatact 56820
atagttagca ctcttccatg tcctgcatgt agacggcacg cgactatcgc tatagaggac 56880
aataatgtca tgtctagcga tgatctgaat tatatttatt attttttcat cagattattt 56940
aacaatttgg catctgatcc caaatacgcg atcgatgtga caaaggttaa ccctttataa 57000
acttaaccca ttataaaact tatgattagt cacgactgaa ataaccgcgt gattattttt 57060
tggtataatt ctacacggca tggtttctgt gactatgaat tcaacccccg ttacattagt 57120
gaaatcttta acaaacagca agggttcgtc aaagacataa aactcattgt ttacaatcga 57180
aatagacccc ctatcacact taaaataaaa aatatcctta tcctttacca ccaaataaaa 57240
ttctgattgg tcaatgtgaa tgtattcact taacagttcc acaaatttat ttattaactc 57300
cgaggcacat acatcgtcgg tattttttat ggcaaacttt actcttccag catccgtttc 57360
taaaaaaata ttaacgagtt ccatttatat catccaatat tattgaaatg acgttgatgg 57420
acaaatgata caaataagaa ggtacggtac ctttgtccac catctcctcc aattcatgct 57480
ctattttgtc attaacttta atgtatgaaa acagtacgcc acatgcttcc atgacagtgt 57540
gtaacacttt ggatacaaaa tgtttgacat tagtataatt gttcaagact gtcaatctat 57600
aatagatagt agctataata tattctatga tggtattgaa gaagatgaca accttggcat 57660
attgatcatt taacacagac atggtatcaa cagatagctt gaatgaaaga gaatcagtaa 57720
ttggaataag cgtcttctcg atggagtgtc cgtataccaa catgtctgat attttgatgt 57780
attccattaa attatttagt tttttctttt tattctcgtt aaacagcatt tctgtcaacg 57840
gaccccaaca tcgttgaccg attaagtttt gattgatttt tccgtgtaag gcgtatctag 57900
tcagatcgta tagcctatcc aataatccat cgtctgtgtg tagatcacat cgtacacttt 57960
ttaattctct atagaagagc gacagacatc tggagcaatt acagacagca atttctttat 58020
tctctacaga tgtaagatac ttgaagacat tcctatgatg atgcagaatt ttggataaca 58080
cggtattgat ggtatctgtt accataattc ctttgatggc tgatagtgtc agagcacaag 58140
atttccaatc tttgacaatt tttagcacca ttatctttgt tttgatatct atatcagaca 58200
gcatggtgcg tctgacaaca caaggattaa gacggaaaga tgaaatgatt ctctcaacat 58260
cttcaatgga taccttgcta ttttttctgg cattatctat atgtgcgaga atatcctcta 58320
gagaatcagt atcctttttg atgatagtgg atctcaatga catgggacgt ctaaaccttc 58380
ttattctatc accagattgc atggtgattt gtcttctttc ttttatcata atgtaatctc 58440
taaattcatc ggcaaattgt ctatatctaa aatcataata tgagatgttt acctctacaa 58500
atatctgttc gtccaatgtt agagtattta catcagtttt gtattccaaa ttaaacatgg 58560
caacggattt aattttatat tcctctatta agtcctcgtc gataataaca gaatgtagat 58620
aatcatttaa tccatcgtac atggttggaa gatgctcgtt gacaaaatct ttaattgtct 58680
tgatgaaggt gggactatat ctaacatctt gattaataaa atttataaca ttgtccatag 58740
gatactttgt aactagtttt atacacatct cttcatcggt aagtttagac agaatatcgt 58800
gaacaggtgg tatattatat tcatcagata tacgaagaac aatgtccaaa tctatattgt 58860
ttaatatatt atatagatgt agtgtagctc ctacaggaat atctttaact aagtcaatga 58920
tttcatcaac cgttagatct attttaaagt taatcatata ggcattgatt tttaaaaggt 58980
atgtagcctt gactacattc tcattaatta accattccaa gtcactgtgt gtaagaagat 59040
tatattctat cataagcttg actacatttg gtcccgatac cattaaagaa ttcttatgat 59100
ataaggaaac agattttagg tactcatcta ctctacaaga attttggaga gccttaacga 59160
tatcagtgac gtttattatt tcaggaggaa aaaacctaac attgagaata tcggaattaa 59220
tagcttccag atacagtgat tttggcaata gtccgtgtaa tccataatcc agtaacacga 59280
gctggtgctt gctagacacc ttttcaatgt ttaatttttt tgaaataagc tttgataaag 59340
ccttcctcgc aaattccgga tacatgaaca tgtcggcgac atgattaagt attgtttttt 59400
cattattttt atattttctc aacaagttct caatacccca atagatgata gaatatcacc 59460
caatgcgtcc atgttgtcta tttccaacag gtcgctatat ccaccaatag aagttttccc 59520
aaaaaagatt ctaggaacag ttctaccacc agtaatttgt tcaaaatagt cacgcaattc 59580
attttcgggt ttaaattctt taatatcgac aatttcatac gctcctcttt tgaaactaaa 59640
cttatttaga atatccagtg catttctaca aaaaggacat gtatacttga caaaaattgt 59700
cactttgtta ttggccaacc tttgttgtac aaattcctcg gccattttaa tatttaagtg 59760
atataaaact atctcgactt atttaactct ttagtcgaga tatatggacg cagatagcta 59820
tatgatagcc aactacagaa ggcaaacgct ataaaaaaca taattacgac gagcatattt 59880
ataaatattt ttattcagca ttacttgata tagtaatatt aggcacagtc aaacattcaa 59940
ccactctcga tacattaact ctctcatttt ctttaacaaa ttctgcaata tcttcgtaaa 60000
aagattcttg aaacttttta gaatatctat cgactctaga tgaaatagcg ttcgtcaaca 60060
tactatgttt tgtatacata aaggcgccca ttttaacagt ttctagtgac aaaatgctag 60120
cgatcctagg atcctttaga atcacataga ttgacgattc gtctctctta gtaactctag 60180
taaaataatc atacaatcta gtacgcgaaa taatattatc cttgacttga ggagatctaa 60240
acaatctagt tttgagaaca tcgataagtt catcgggaat gacatacata ctatctttaa 60300
tagaactctt ttcatccagt tgaatggatt cgtccttaac caactgatta atgagatctt 60360
ctattttatc attttccaga tgatatgtat gtccattaaa gttaaattgt gtagcgcttc 60420
tttttagtct agcagccaat actttaacat cactaatatc gatatacaaa ggagatgatt 60480
tatctatggt attaagaatt cgtttttcga catctgtcaa aaccaattcc tttttgcctg 60540
tatcatccag ttttccatcc tttgtaaaga aattattttc tactagacta ttaataagac 60600
tgataaggat tcctccataa ttgcacaatc caaacttttt cacaaaacta gactttacaa 60660
gatctacagg aatgcgtact tcaggtttct tagcttgtga ttttttcttt tgtggacatt 60720
ttcttgtgac caactcatct accatttcat tgattttagc agtgaaataa gctttcaatg 60780
cacgggcact gatactattg aaaacgagtt gatcttcaaa ttccgccatt taagttcacc 60840
aaacaacttt taaatacaaa tatatcaata gtagtagaat aagaactata aaaaaaataa 60900
taattaacca ataccaaccc caacaaccgg tattattagt tgatgtgact gttttctcat 60960
cacttagaac agatttaaca atttctataa agtctgtcaa atcatcttcc ggagacccca 61020
taaatacacc aaatatagcg gcgtacaact tatccattta tacattgaat attggctttt 61080
ctttatcgct atcttcatca tattcatcat caatatcaac aagtcccaga ttacgagcca 61140
gatcttcttc tacattttca gtcattgata cacgttcact atctccagag agtccgataa 61200
cgttagccac cacttctcta tcaatgatta gtttcttgag tgcgaatgta atttttgttt 61260
ccgttccgga tctatagaaa actacaggtg tgataattgc cttggccaat tgtctttctc 61320
ttttactgag tgattctagt tcaccttcta tagatctgag aatggatgat tctccagtcg 61380
aaacatattc taccatggct ccgtttaatt tgttgatgaa gatggattca tccttaaatg 61440
ttttctctgt aatagtttcc accgaaagac tatgcaaaga atttggaatg cgttccttgt 61500
gcttaatgtt tccatagacg gcttctagaa gttgatacaa cataggacta gccgcggtaa 61560
cttttatttt tagaaagtat ccatcgcttc tatcttgttt agatttattt ttataaagtt 61620
tagtctctcc ttccaacata ataaaagtgg aagtcatttg actagataaa ctatcagtaa 61680
gttttataga gatagacgaa caattagcgt attgagaagc atttagtgta acgtattcga 61740
tacattttgc attagattta ctaatcgatt ttgcatactc tataacaccc gcacaagtct 61800
gtagagaatc gctagatgca gtaggtcttg gtgaagtttc aactctcttc ttgattacct 61860
tactcatgat taaacctaaa taattgtact ttgtaatata atgatatata ttttcacttt 61920
atctcatttg agaataaaaa tgtttttgtt taaccactgc atgatgtaca gatttcggaa 61980
tcacaaacca ccggtggttt tattttatcc ttgtccaatg tgaattgaat gggagcggat 62040
gcgggtttcg tacgtagata gtacattccc gtttttagac cgagactcca tccgtaaaaa 62100
tgcatactcg ttagtttgga ataactcgga tctgctatat ggatattcat agattgactt 62160
tgatcgatga aggctcccct gtctgcagcc atttttatga tcgtcttttg tggaatttcc 62220
caaatagttt tataaactcg cttaatatct tctggaaggt ttgtattctg aatggatcca 62280
ccatctgcca taatcctatt cttgatctca tcattccata attttctctc ggttaaaact 62340
ctaaggagat gcggattaac tacttgaaat tctccagaca atactctccg agtgtaaata 62400
ttactggtat acggttccac cgactcatta tttcccaaaa tttgagcagt tgatgcagtc 62460
ggcataggtg ccaccaataa actatttcta agaccgtatg ttctgatttt atcttttaga 62520
ggttcccaat tccaaagatc cgacggtaca acattccaaa gatcatattg tagaataccg 62580
ttactggcgt acgatcctac atatgtatcg tatggtcctt ccttctcagc tagttcacaa 62640
ctcgcctcta atgcaccgta ataaatggtt tcgaagatct tcttatttag atcttgtgct 62700
tccaggctat caaatggata atttaagaga ataaacgcgt ccgctaatcc ttgaacacca 62760
ataccgatag gtctatgtct cttattagag atttcagctt ctggaatagg ataataatta 62820
atatctataa ttttattgag atttctgaca attactttga ccacatcctt cagtttgaga 62880
aaatcaaatc gcccatctat tacaaacatg ttcaaggcaa cagatgccag attacaaacg 62940
gctacctcat tagcatccgc atattgtatt atctcagtgc aaagattact acacttgata 63000
gttcctaaat tttgttgatt actctttttg ttacacgcat ccttataaag aatgaatgga 63060
gtaccagttt caatctgaga ttctataatc gctttccaga cgactcgagc ctttattata 63120
gatttgtatc tcctttctct ttcgtatagt gtatacaatc gttcgaactc gtctccccaa 63180
acattgtcca atccaggaca ttcatccgga cacatcaacg accactctcc gtcatccttc 63240
actcgtttca taaagagatc aggaatccaa agagctataa atagatctct ggttctatgt 63300
tcctcgtttc ctgtattctt tttaagatcg aggaacgcca taatatcaga atgccacggt 63360
tccaagtata tggccataac tccaggccgt ttgtttcctc cctgatctat gtatctagcg 63420
gtgttattat aaactctcaa cattggaata ataccgtttg atataccatt ggtaccggag 63480
atatagcttc cactggcacg aatattacta attgatagac ctattccccc tgccatttta 63540
gagattaatg cgcatcgttt taacgtgtca tagataccct ctatgctatc atcgatcatg 63600
ttaagtagaa aacagctaga catttggtga cgactagttc ccgcattaaa taaggtagga 63660
gaagcgtgcg taaaccattt ttcagaaagt agattgtacg tctcaatagc tgagtctata 63720
tcccattgat gaattcctac tgcgacacgc attaacatgt gctgaggtct ttcaacgatc 63780
ttgttgttta ttttcaacaa gtaggatttt tccaaagttt taaaaccaaa atagttgtat 63840
gaaaagtctc gttcgtaaat aataaccgag ttgagtttat ccttatattt gttaactata 63900
tccatggtga tacttgaaat aatcggagaa tgtttcccat ttttaggatt aacatagttg 63960
aataaatcct ccatcacttc actaaatagt ttttttgttt ccttgtgtag atttgatacg 64020
gctattctgg cggctagaat ggcataatcc ggatgttgtg tagtacaagt ggctgctatt 64080
tcggctgcca gagtgtccaa ttctaccgtt gttactccat tatatattcc ttgaataacc 64140
ttcatagcta ttttaatagg atctatatga tccgtgttta agccataaca taattttcta 64200
atacgagacg tgattttatc aaacatgaca ttttccttgt atccatttcg tttaatgaca 64260
aacatttttg ttggtgtaat aaaaaaatta tttaactttt cattaatagg gatttgacgt 64320
acgtagcgta caaaatgatt gttcctggta tatagataaa gagtcctata tatttgaaaa 64380
tcgttacggc tcgattaaac tttaatgatt gcatagtgaa tatatcatta ggatttaact 64440
ccttgactat cagggcggca ccagaaatta ccatcaaaag cattaataca gttatgccta 64500
tcgcagttag aacggttata gcatccacca tttatatcta aaaattagat caaagaatat 64560
gtgacaaagt cctagttgta tattgagaat tgacaaaaca atgtttctta catatttttt 64620
ttttattagt aaccgactta atagtaggaa ctggaaaact agacttgatt attctataag 64680
tatagatacc cttccaaata atattctctt tgataaaagt tccagaaaat gtagaatttt 64740
ttaaaaagtt atcttttgct attaccaaga ttgtgtttag acgcttatta ttaatatgag 64800
tgatgaaatc cacaccgcct ctagatatcg cctttatttc cacattagat ggtaaatcca 64860
atagtgaaac tatcttttta ggaatgtatg gactcgcgtt tagaggagtg aacgtcttgg 64920
gcgtcggaaa ggatgattcg tcaaacgaat aaacaatttc acaaatggat gttaatgtat 64980
tagtaggaaa ttttttgacg ctagtggaat tgaaaattct aatggatgat gttctaccta 65040
tttcatccga taacatgtta atttccgaca ccaacggttt taatatttcg atgatatacg 65100
gtagtctctc tttcggactt atatagctta ttccacaata cgagtcatta tatactccaa 65160
aaaacaaaat aactagtata aaatctgtat cgaatgggaa aaacgaaatt atcgacatag 65220
gtatagaatc cggaacattg aacgtattaa tacttaattc tttttctgtg gtaagtaccg 65280
ataggttatt gacattgtat ggttttaaat attctataac ttgagacttg atagatatta 65340
gtgatgaatt gaaaattatt tttatcacca cgtgtgtttc aggatcatcg tcgacgcccg 65400
tcaaccaacc gaacggagta aaataaatat cattaatata tgctctagat attagtattt 65460
ttatcaatcc tttgattatc atcttctcgt aggcgaatga ttccatgatc aagagtgatt 65520
taagaacatc ctccggagta ttaatgggct tagtaaacag tccatcgttg caataataaa 65580
agttatccaa gttaaaggat attatgcatt cgtttaaaga tatcacctca tctgacggag 65640
acaatttttt ggtaggtttt agagactttg aagctacttg tttaacaaag ttattcatcg 65700
tcgtttacta ttctatttaa ttttgtagtt aatttatcac atatcacatt aattgacttt 65760
ttggtccatt tttccatacg tttatattct tttaatcctg cgttatccgt ttccgttata 65820
tccagtgata gatcgtgcag gttaaataga atgctcttaa ataatgtcat ttttttatcc 65880
gctaaaaatt taaagaatgt ataaactttt ttcaaagatt taaaactttt aggtggtgtc 65940
ctagtacaca atatcataaa caaactaata aacatcccgc attcagattc caacagctga 66000
ttaacttcca cattaataca gcctattttc gctccaaatg tacattcgaa aaatctgaat 66060
aaaacatcaa tgtcgcaatt tgtattatcc aatacagaat gtttgtgatt cgtgttaaaa 66120
ccatcggaga aggaatagaa ataaaaatta ttatagtggt ggaattcagt tggaatattg 66180
cctccggagt cataaaagga tactaaacat tgttttttat cataaattac acatttccaa 66240
tgagacaaat aacaaaatcc aaacattaca aatctagagg tagaactttt aattttgtct 66300
ttaagtatat acgataagat atgtttattc ataaacgcgt caaatttttc atgaatcgct 66360
aaggagttta agaatctcat gtcaaattgt cctatataat ccacttcgga tccataagca 66420
aactgagaga ctaagttctt aatacttcga ttgctcatcc aggctcctct ctcaggctct 66480
attttcatct tgacgacctt tggattttca ccagtatgta ttcctttttt ttctagacac 66540
taaataaaat atttaaaata taatattaat gtactaaaac ttatatatta ttaatttatc 66600
taactaaagt tagtaaatta tatatataat tttataatta atttaatttt actaatttta 66660
tttagtgtct agaaaaaaa 66679
<210> 17
<211> 68308
<212> DNA
<213> 人工序列
<220>
<223> sVAC片段2
<400> 17
tttttttcta gacactaaat aaaatattta aaatataata ttaatgtact aaaacttata 60
tattattaat ttatctaact aaagttagta aattatatat ataattttat aattaattta 120
attttactaa ttttatttag tgtctagaaa aaaaccccct gccattttag agattaatgc 180
gcatcgtttt aacgtgtcat agataccctc tatgctatca tcgatcatgt taagtagaaa 240
acagctagac atttggtgac gactagttcc cgcattaaat aaggtaggag aagcgtgcgt 300
aaaccatttt tcagaaagta gattgtacgt ctcaatagct gagtctatat cccattgatg 360
aattcctact gcgacacgca ttaacatgtg ctgaggtctt tcaacgatct tgttgtttat 420
tttcaacaag taggattttt ccaaagtttt aaaaccaaaa tagttgtatg aaaagtctcg 480
ttcgtaaata ataaccgagt tgagtttatc cttatatttg ttaactatat ccatggtgat 540
acttgaaata atcggagaat gtttcccatt tttaggatta acatagttga ataaatcctc 600
catcacttca ctaaatagtt tttttgtttc cttgtgtaga tttgatacgg ctattctggc 660
ggctagaatg gcataatccg gatgttgtgt agtacaagtg gctgctattt cggctgccag 720
agtgtccaat tctaccgttg ttactccatt atatattcct tgaataacct tcatagctat 780
tttaatagga tctatatgat ccgtgtttaa gccataacat aattttctaa tacgagacgt 840
gattttatca aacatgacat tttccttgta tccatttcgt ttaatgacaa acatttttgt 900
tggtgtaata aaaaaattat ttaacttttc attaataggg atttgacgta cgtagcgtac 960
aaaatgattg ttcctggtat atagataaag agtcctatat atttgaaaat cgttacggct 1020
cgattaaact ttaatgattg catagtgaat atatcattag gatttaactc cttgactatc 1080
agggcggcac cagaaattac catcaaaagc attaatacag ttatgcctat cgcagttaga 1140
acggttatag catccaccat ttatatctaa aaattagatc aaagaatatg tgacaaagtc 1200
ctagttgtat attgagaatt gacaaaacaa tgtttcttac atattttttt tttattagta 1260
accgacttaa tagtaggaac tggaaaacta gacttgatta ttctataagt atagataccc 1320
ttccaaataa tattctcttt gataaaagtt ccagaaaatg tagaattttt taaaaagtta 1380
tcttttgcta ttaccaagat tgtgtttaga cgcttattat taatatgagt gatgaaatcc 1440
acaccgcctc tagatatcgc ctttatttcc acattagatg gtaaatccaa tagtgaaact 1500
atctttttag gaatgtatgg actcgcgttt agaggagtga acgtcttggg cgtcggaaag 1560
gatgattcgt caaacgaata aacaatttca caaatggatg ttaatgtatt agtaggaaat 1620
tttttgacgc tagtggaatt gaaaattcta atggatgatg ttctacctat ttcatccgat 1680
aacatgttaa tttccgacac caacggtttt aatatttcga tgatatacgg tagtctctct 1740
ttcggactta tatagcttat tccacaatac gagtcattat atactccaaa aaacaaaata 1800
actagtataa aatctgtatc gaatgggaaa aacgaaatta tcgacatagg tatagaatcc 1860
ggaacattga acgtattaat acttaattct ttttctgtgg taagtaccga taggttattg 1920
acattgtatg gttttaaata ttctataact tgagacttga tagatattag tgatgaattg 1980
aaaattattt ttatcaccac gtgtgtttca ggatcatcgt cgacgcccgt caaccaaccg 2040
aacggagtaa aataaatatc attaatatat gctctagata ttagtatttt tatcaatcct 2100
ttgattatca tcttctcgta ggcgaatgat tccatgatca agagtgattt aagaacatcc 2160
tccggagtat taatgggctt agtaaacagt ccatcgttgc aataataaaa gttatccaag 2220
ttaaaggata ttatgcattc gtttaaagat atcacctcat ctgacggaga caattttttg 2280
gtaggtttta gagactttga agctacttgt ttaacaaagt tattcatcgt cgtttactat 2340
tctatttaat tttgtagtta atttatcaca tatcacatta attgactttt tggtccattt 2400
ttccatacgt ttatattctt ttaatcctgc gttatccgtt tccgttatat ccagtgatag 2460
atcgtgcagg ttaaatagaa tgctcttaaa taatgtcatt tttttatccg ctaaaaattt 2520
aaagaatgta taaacttttt tcaaagattt aaaactttta ggtggtgtcc tagtacacaa 2580
tatcataaac aaactaataa acatcccgca ttcagattcc aacagctgat taacttccac 2640
attaatacag cctattttcg ctccaaatgt acattcgaaa aatctgaata aaacatcaat 2700
gtcgcaattt gtattatcca atacagaatg tttgtgattc gtgttaaaac catcggagaa 2760
ggaatagaaa taaaaattat tatagtggtg gaattcagtt ggaatattgc ctccggagtc 2820
ataaaaggat actaaacatt gttttttatc ataaattaca catttccaat gagacaaata 2880
acaaaatcca aacattacaa atctagaggt agaactttta attttgtctt taagtatata 2940
cgataagata tgtttattca taaacgcgtc aaatttttca tgaatcgcta aggagtttaa 3000
gaatctcatg tcaaattgtc ctatataatc cacttcggat ccataagcaa actgagagac 3060
taagttctta atacttcgat tgctcatcca ggctcctctc tcaggctcta ttttcatctt 3120
gacgaccttt ggattttcac cagtatgtat tcctttacgt gataaatcat cgattttcaa 3180
atccatttgt gagaagtcta tcgccttaga tactttttcc cgtagtcgag gtttaaagaa 3240
atacgctaac ggtatactag taggtaactc aaaaacatca tatatagaat ggtaacgcgt 3300
ctttaactcg tcggttaact ctttcttttg atcgagttcg tcgctactat tgggtctgct 3360
caggtgcccc gactctacta gttccaacat cataccgata ggaatacaag acactttgcc 3420
ggcggttgta gatttatcat atttttccac tacatatccg ttacaatttg ttaaaaattt 3480
agatacatct atattgctac ataatccagc tagtgaatat atatgacata ataaattggt 3540
aaatcctagt tctggtattt tactaattac taaatctgta tatctttcca tttatcatgg 3600
aaaagaattt accagatatc ttcttttttc caaactgcgt taatgtattc tcttacaaat 3660
attcacaaga tgaattcagt aatatgagta aaacggaacg tgatagtttc tcattggccg 3720
tgtttccagt tataaaacat agatggcata acgcacacgt tgtaaaacat aaaggaatat 3780
acaaagttag tacagaagca cgtggaaaaa aagtatctcc tccatcacta ggaaaacccg 3840
cacacataaa cctaaccgcg aagcaatata tatacagtga acacacaata agctttgaat 3900
gttatagttt tctaaaatgt ataacaaata cagaaatcaa ttcgttcgat gagtatatat 3960
taagaggact attagaagct ggtaatagtt tacagatatt ttccaattcc gtaggtaaac 4020
gaacagatac tataggtgta ctagggaata agtatccatt tagcaaaatt ccattggcct 4080
cattaactcc taaagcacaa cgagagatat tttcagcgtg gatttctcat agacctgtag 4140
ttttaactgg aggaactgga gtgggtaaga cgtcacaggt acccaagtta ttgctttggt 4200
ttaattattt atttggtgga ttctctactc tagataaaat cactaacttt cacgaaagac 4260
cagtcattct atctcttcct aggatagctt tagttagatt gcatagcaat accattttaa 4320
aatcattggg atttaaggta ctagatggat ctcctatttc tttacggtac ggatctatac 4380
cggaagaatt aataaacaaa caaccaaaaa aatatggaat tgtattttct acccataagt 4440
tatctctaac aaaactattt agttatggca ctcttattat agacgaagtt catgagcatg 4500
atcaaatagg agatattatt atagcagtag cgagaaagca tcatacgaaa atagattcta 4560
tgtttttaat gactgccacg ttagaggatg accgagaacg gctaaaagta tttttaccta 4620
atcccgcatt tatacatatt cctggagata cactgtttaa aattagcgag gtatttattc 4680
ataataagat aaatccatct tccagaatgg catacataga agaagaaaag agaaatttag 4740
ttactgctat acagatgtat actcctcctg atggatcatc cggtatagtc tttgtggcat 4800
ccgttgcaca gtgtcacgaa tataaatcat atttagaaaa aagattaccg tatgatatgt 4860
atattattca tggtaaggtc ttagatatag acgaaatatt agaaaaagtg tattcatcac 4920
ctaatgtatc gataattatt tctactcctt atttggaatc cagcgttact atacgcaatg 4980
ttacacacat ttatgatatg ggtaaagttt ttgtccccgc tccttttgga ggatcgcaag 5040
aatttatttc taaatctatg agagatcaac gaaaaggaag agtaggaaga gttaatcctg 5100
gtacatacgt ctatttctat gatctgtctt atatgaagtc tatacagcga atagattcag 5160
aatttctaca taattatata ttgtacgcta ataagtttaa tctaacactc cccgaagatt 5220
tgtttataat ccctacaaat ttggatattc tatggcgtac aaaggaatat atagactcgt 5280
tcgatattag tacagaaaca tggaataaat tattatccaa ttattatatg aagatgatag 5340
agtatgctaa actttatgta ctaagtccta ttctcgctga ggagttggat aactttgaga 5400
ggacgggaga attaactagt attgtacgag aagccatttt atctctaaat ttacgaatta 5460
agattttaaa ttttaaacat aaagatgatg atacgtatat acacttttgt aaaatattat 5520
tcggtgtcta taacggaaca aacgctacta tatattatca tagacctcta acgggatata 5580
tgaatatgat ttcagatact atatttgttc ctgtagataa taactaaaaa tcaaactcta 5640
atgaccacat ctttttttag agatgaaaaa ttttctacat ctccttttgt agacacgact 5700
aaacattttg caaaaaaaag tttattagtg tttagataat cgtatacttc atcagtgtag 5760
atagtaaatg tgaacaaata aaaggtattc ttactcaata gattggtaaa ttccatagaa 5820
tatattaatc ctttcttctt gagatcccac atcatttcaa ccagagacgt tttatccaat 5880
gatttacctc gtactatacc acatacaaaa ctagattttg cagtgacgtc gtacctggta 5940
ttcctaccaa acaaaatttt acttttagtt cttttagaaa attctaaggt agaatctcta 6000
tttgccaata tgtcatctat ggaattacca ctagcaaaaa atgatagaaa tatatattga 6060
tacatcgcag ctggttttga tctactatac tttaaaaacg aatcagattc cataattgcc 6120
tgtatatcat cagctgaaaa actatgtttt acacgtattc cttcggcatt tctttttaat 6180
gatatatctt gtttagacaa tgataaagtt atcatgtcca tgagagacgc gtctccgtat 6240
cgtataaata tttcattaga tgttagacgc ttcattaggg gtatacttct ataaggtttc 6300
ttaatcagtc catcattggt tgcgtcaaga actactatcg gatgttgttg ggtatctcta 6360
gtgttacaca tggccttact aaagtttggg taaataacta tgatatctct attaattata 6420
gatgcatata tttcattcgt caaggatatt agtatcgact tgctatcgtc attaatacgt 6480
gtaatgtaat catataaatc atgcgatagc caaggaaaat tcaaatagat gttcatcata 6540
taatcgtcgc tataattcat attaatacgt tgacattgac taatttgtaa tatagcctcg 6600
ccacgaagaa agctctcgta ttcagtttca tcgataaagg ataccgttaa atataactgg 6660
ttgccgatag tctcatagtc tattaagtgg taagtttcgt acaaatacag aatccctaaa 6720
atattatcta atgttggatt aatctttacc ataactgtat aaaatggaga cggagtcata 6780
actattttac cgtttgtact tactggaata gacgaaggaa taatctccgg acatgctggt 6840
aaagacccaa atgtctgttt gaagaaatcc aatgttccag gtcctaatct cttaacaaaa 6900
attacgatat tcgatcccga tatcctttgc attctattta ccagcatatc acgaactata 6960
ttaagattat ctatcatgtc tattctccca ccgttatata aatcgcctcc gctaagaaac 7020
gttagtatat ccatacaatg gaatacttca tttctaaaat agtattcgtt ttctaattct 7080
ttaatgtgaa atcgtatact agaaagggaa aaattatctt tgagttttcc gttagaaaag 7140
aaccacgaaa ctaatgttct gattgcgtcc gattccgttg ctgaattaat ggatttacac 7200
caaaaactca tataacttct agatgtagaa gcattcgcta aaaaattagt agaatcaaag 7260
gatataagta gatgttccaa caagtgagca attcccaaga tttcatctat atcattctcg 7320
aatccgaaat tagaaattcc caagtagata tcctttttca tccgatcgtt gatgaaaata 7380
cgaactttat tcggtaagac aatcatttac taaggagtaa aataggaagt aatgttcgta 7440
tgtcgttatc atcgtataaa ttaaaggtgt gttttttacc attaagtgac attataattt 7500
taccaatatt ggaattataa tataggtgta tttgcgcact cgcgacggtt gatgcatcgg 7560
taaatatagc tgtatctaat gttctagtcg gtatttcatc atttcgctgt ctaataatag 7620
cgttttctct atctgtttcc attacagctg cctgaagttt attggtcgga taatatgtaa 7680
aataataaga aatacatacg aataacaaaa ataaaataag atataataaa gatgccattt 7740
agagatctaa ttttgttcaa cttgtccaaa ttcctactta cagaagatga ggaatcgttg 7800
gagatagtgt cttccttatg tagaggattt gaaatatctt atgatgactt gataacttac 7860
tttccagata ggaaatacca taaatatatt tctaaagtat ttgaacatgt agatttatcg 7920
gaggaattaa gtatggaatt ccatgataca actttgcgag atttagtcta tcttagattg 7980
tacaagtatt ccaagtgtat acggccgtgt tataaattag gagataatct aaaaggcata 8040
gttgttataa aggacaggaa tatttatatt agggaagcaa atgatgactt gatagaatat 8100
ctcctcaagg aatacactcc tcagatttat acatattcta atgagcgcgt ccccataact 8160
ggttcaaaat taattctttg tggattttct caagttacat ttatggcgta tacaacgtcg 8220
catataacaa caaataaaaa ggtagatgtt ctcgtttcca aaaaatgtat agatgaacta 8280
gtcgatccaa taaattatca aatacttcaa aatttatttg ataaaggaag cggaacaata 8340
aacaaaatac tcaggaagat attttattcg gtaacaggtg gccaaactcc ataggtagct 8400
ttttctattt cggattttag aatttccaaa ttcaccagcg atttatctgt tttggtgaaa 8460
tccaaggatt tattaatgtc cacaaatgcc atttgttttg tctgtggatt gtatttgaaa 8520
atggaaacga tgtagttaga tagatgcgct gcgaagtttc ctattagggt tccgcgcttc 8580
acgtcaccca gcatacttga atcaccatcc tttaaaaaaa atgataagat atcaacatgg 8640
agtatatcat actcggattt taattcttct actgcatcac tgacattttc acaaatacta 8700
caatacggtt taccgaaaat aatcagtacg ttcttcattt atgggtatca aaaacttaaa 8760
atcgttactg ctggaaaata aatcactgac gatattagat gataatttat acaaagtata 8820
caatggaata tttgtggata caatgagtat ttatatagcc gtcgccaatt gtgtcagaaa 8880
cttagaagag ttaactacgg tattcataaa atacgtaaac ggatgggtaa aaaagggagg 8940
gcatgtaacc ctttttatcg atagaggaag tataaaaatt aaacaagacg ttagagacaa 9000
gagacgtaaa tattctaaat taaccaagga cagaaaaatg ctagaattag aaaagtgtac 9060
atccgaaata caaaatgtta ccggatttat ggaagaagaa ataaaggcag aaatgcaatt 9120
aaaaatcgat aaactcacat ttcaaatata tttatctgat tctgataaca taaaaatatc 9180
attgaatgag atactaacac atttcaacaa taatgagaat gttacattat tttattgtga 9240
tgaacgagac gcagaattcg ttatgtgtct cgaggctaaa acacatttct ctaccacagg 9300
agaatggccg ttgataataa gtaccgatca ggatactatg ctatttgcat ctgctgataa 9360
tcatcctaag atgataaaaa acttaactca actgtttaaa tatgttccat ctgcagagga 9420
taactattta gcaaaattaa cggcgttagt gaatggatgt gatttctttc ctggactcta 9480
tggggcatct ataacaccca acaacttaaa caaaatacaa ttgtttagtg attttacaat 9540
cgataatata gtcactagtt tggcaattaa aaattattat agaaagacta actctaccgt 9600
agacgtgcgt aatattgtta cgtttataaa cgattacgct aatttagacg atgtctactc 9660
gtatattcct ccttgtcaat gcactgttca agaatttata ttttccgcat tagatgaaaa 9720
atggaatgaa tttaaatcat cttatttaga aagcgtgccg ttaccctgcc aattaatgta 9780
tgcgttagaa ccacgcaagg agattgatgt ttcagaagtt aaaactttat catcttatat 9840
agatttcgaa aatactaaat cagatatcga tgttataaaa tctatatcct cgatcttcgg 9900
atattctaac gaaaactgta acacgatagt attcggcatc tataaggata atttactact 9960
gagtataaat agttcatttt actttaacga tagtctgtta ataaccaata ctaaaagtga 10020
taatataata aatataggtt actagattaa aaatggtgtt ccaactcgtg tgctctacgt 10080
gcggcaaaga tatttctcac gaacgatata aattgattat acgaaaaaaa tcattaaagg 10140
atgtactcgt cagtgtaaag aacgaatgtt gtaggttaaa attatctaca caaatagaac 10200
ctcaacgtaa cttaacagtg caacctctat tggatataaa ctaatatgga tccggttaat 10260
tttatcaaga catatgcgcc tagaggttct attattttta ttaattatac catgtcatta 10320
acaagtcatt tgaatccatc gatagaaaaa catgtgggta tttattatgg tacgttatta 10380
tcggaacact tggtagttga atcaacatat agaaaaggag ttcgaatagt cccattggat 10440
agtttttttg aaggatatct tagtgcaaaa gtatacatgt tagagaatat tcaagttatg 10500
aaaatagcag ctgatacgtc attaacttta ttgggtattc cgtatggatt tggtcatgat 10560
agaatgtatt gttttaaatt ggtagctgac tgttataaaa atgccggtat tgatacatcg 10620
tctaaacgaa tattaggtaa agatattttt ctgagccaaa acttcacaga cgataataga 10680
tggataaaga tatatgattc taataattta acattttggc aaattgatta ccttaaaggg 10740
tgagttaata tgcataacta ctcctccgtt gttttttccc tcgttctttt tcttaacgtt 10800
gtttgccatc actctcataa tgtaaagata ttctaaaatg gtaaactttt gcatatcgga 10860
cgcagaaatt ggtataaatg ttgtaattgt attatttccc gtcaatggac tagtcacagc 10920
tccatcagtt ttatatcctt tagagtattt ctcactcgtg tctaacattc tagagcattc 10980
catgatctgt ttatcgttga tattggccgg aaagatagat tttttatttt ttattatatt 11040
actattggca attgtagata taacttctgg taaatatttt tctacctttt caatctcttc 11100
tattttcaag ccggctatat attctgctat attgttgcta gtatcaatac cttttctggc 11160
taagaagtca tatgtggtat tcactatatc agttttaact ggtagttcca ttagcctttc 11220
cacttctgca gaataatcag aaattggttc tttaccagaa aatccagcta ctataatagg 11280
ctcaccgatg atcattggca aaatcctata ttgtaccaga ttaatgagag catatttcat 11340
ttccaataat tctgctagtt cttgagacat tgatttattt gatgaatcta gttggttctc 11400
tagatactct accatttctg ccgcatacaa taacttgtta gataaaatca gggttatcaa 11460
agtgtttagc gtggctagaa tagtgggctt gcatgtatta aagaatgcgg tagtatgagt 11520
aaaccgtttt aacgaattat atagtctcca gaaatctgtg gcgttacata catgagccga 11580
atgacatcga agattgtcca atatttttaa tagctgctct ttgtccatta tttctatatt 11640
tgactcgcaa caattgtaga taccattaat caccgattcc tttttcgatg ccggacaata 11700
gcacaattgt ttagctttgg actctatgta ttcagaatta atagatatat ctcttaatac 11760
agattgcact atacattttg aaactatgtc aaaaattgta gaacgacgct gttctgcagc 11820
catttaactt taaataattt acaaaaattt aaaatgagca tccgtataaa aatcgataaa 11880
ctgcgccaaa ttgtggcata tttttcagag ttcagtgaag aagtatctat aaatgtagac 11940
tcgacggatg agttaatgta tatttttgcc gccttgggcg gatctgtaaa catttgggcc 12000
attatacctc tcagtgcatc agtgttctac cgcggagccg aaaatattgt gtttaatctt 12060
cctgtgtcca aggtaaaatc gtgtttgtgt agttttcaca atgatgccat catagatata 12120
gaacctgatc tggaaaataa tctagtaaaa ctttctagtt atcatgtagt aagtgtcgat 12180
tgtaataagg aactgatgcc tattaggaca gatactacta tttgtctaag tatagatcaa 12240
aagaaatctt acgtgtttaa ttttcacaag tatgaagaaa aatgttgtgg tagaaccgtc 12300
attcatttag aatggttgtt gggctttatc aagtgtatta gtcagcatca gcatttggct 12360
attatgttta aagatgacaa tattattatg aagactcctg gtaatactga tgcattttcc 12420
agggaatatt ctatgactga atgttctcaa gaactacaaa agttttcttt caaaatagct 12480
atctcgtctc tcaacaaact acgaggattc aaaaagagag tcaatgtttt tgaaactaga 12540
atcgtaatgg ataatgacga taacatttta ggaatgttgt tttcggatag agttcaatcc 12600
tttaagatca acatctttat ggcgttttta gattaatact ttcaatgaga taaatatggg 12660
tggcggagta agtgttgagc tccctaaacg ggatccgcct ccgggagtac ccactgatga 12720
gatgttatta aacgtggata aaatgcatga cgtgatagct cccgctaagc ttttagaata 12780
tgtgcatata ggaccactag caaaagataa agaggataaa gtaaagaaaa gatatccaga 12840
gtttagatta gtcaacacag gacccggtgg tctttcggca ttgttaagac aatcgtataa 12900
tggaaccgca cccaattgct gtcgcacttt taatcgtact cattattgga agaaggatgg 12960
aaagatatca gataagtatg aagagggtgc agtattagaa tcgtgttggc cagacgttca 13020
cgacaccgga aaatgcgatg ttgatttatt cgactggtgt cagggggata cgttcgatag 13080
aaacatatgc catcagtgga tcggttcagc ctttaatagg agtaatagaa ctgtagaggg 13140
tcaacaatcg ttaataaatc tgtataataa gatgcaaaca ttatgtagta aagatgctag 13200
tgtaccaata tgtgaatcat ttttgcatca tttacgcgca cacaatacag aagatagcaa 13260
agagatgatc gattatattc taagacaaca gtctgcggac tttaaacaga aatatatgag 13320
atgtagttat cccactagag ataagttaga agagtcatta aaatatgcgg aacctcgaga 13380
atgttgggat ccagagtgtt cgaatgccaa tgttaatttc ttgctaacac gtaattataa 13440
taatttagga ctttgcaata ttgtacgatg taatactagc gtgaacaact tacagatgga 13500
taaaacttcc tcattaagat tgtcatgtgg attaagcaat agtgatagat tttctactgt 13560
tcccgtcaat agagcaaaag tagttcaaca taatattaaa cactcgttcg acctaaaatt 13620
gcatttgatc agtttattat ctctcttggt aatatggata ctaattgtag ctatttaaat 13680
gggtgccgcg gcaagcatac agacgacggt gaatacactc agcgaacgta tctcgtctaa 13740
attagaacaa gaagcgaatg ctagtgctca aacaaaatgt gatatagaaa tcggaaattt 13800
ttatatccga caaaaccatg gatgtaacct cactgttaaa aatatgtgct ctgcggacgc 13860
ggatgctcag ttggatgctg tgttatcagc cgctacagaa acatatagtg gattaacacc 13920
ggaacaaaaa gcatacgtgc cagctatgtt tactgctgcg ttaaacattc agacgagtgt 13980
aaacactgtt gttagagatt ttgaaaatta tgtgaaacag acttgtaatt ctagcgcggt 14040
cgtcgataac aaattaaaga tacaaaacgt aatcatagat gaatgttacg gagccccagg 14100
atctccaaca aatttggaat ttattaatac aggatctagc aaaggaaatt gtgccattaa 14160
ggcgttgatg caattgacga ctaaggccac tactcaaata gcacctaaac aagttgctgg 14220
tacaggagtt cagttttata tgattgttat cggtgttata atattggcag cgttgtttat 14280
gtactatgcc aagcgtatgt tgttcacatc caccaatgat aaaatcaaac ttattttagc 14340
caataaggaa aacgtccatt ggactactta catggacaca ttctttagaa cttctccgat 14400
ggttattgct accacggata tgcaaaactg aaaatatatt gataatattt taatagatta 14460
acatggaagt tatcactgat cgtctagacg atatagtgaa acaaaatata gcggatgaaa 14520
aatttgtaga ttttgttata cacggtctag agcatcaatg tcctgctata cttcgaccat 14580
taattaggtt gtttattgat atactattat ttgttatagt aatttatatt tttacggtac 14640
gtctagtaag tagaaattat caaatgttgt tggcgttggt ggcgctagtc atcacattaa 14700
ctatttttta ttactttata ctataatagt actagactga cttctaacaa acatctcacc 14760
tgccataaat aaatgcttga tattaaagtc ttctatttct aacactattc catctgtgga 14820
aaataatact ctgacattat cgctaattga cacatcggtg agtgatatgc ctataaagta 14880
ataatcttct ttgggcacat ataccagtgt accaggttct aacaacctat ttactggtgc 14940
tcctatagca tactttttct ttaccttgag aatatccatc gtttgcttgg tcaatagcga 15000
tatgtgattt tttatcaacc actcgaaaaa gtaattggag tgttcatatc ctctacgggc 15060
tattgtctca tggccgtgta tgaaatttaa gtaacacgac tgtggtagat ttgttctata 15120
gagccggttg ccgcaaatag atagaactac caatatgtct gtacaaatgt taaacattaa 15180
ttgattaaca gaaaaaacaa tgttcgttct gggaatagaa accagatcaa aacaaaattc 15240
gttagaatat atgccacgtt tatacattga atataaaata actacagttt gaaaaataac 15300
agtatcattt aaacatttaa cttgcggggt taatctcaca actttactgt ttttgaactg 15360
ttcaaaatat agcatagatc cgtgagaaat acgtttagcc gcctttaata gaggaaatcc 15420
caccgccttt ctggatctca ccaacgacga tagttctgac cagcaactca tttcttcatc 15480
atccacctgt tttaacatat aataggcagg agatagatat ccgtcattgc aatattcctt 15540
ctcgtaggca cacaatctaa tattgataaa atctccattc tcttctctgc atttattatc 15600
ttgtttcggt ggctgattag gctgtagtct tggtttaggc tttggtatat cgttgttgaa 15660
tctattttgg tcattaaatc tttcatttct tcctggtata tttttatcac ctcgtttggt 15720
tggatttttg tctatattat cgtttgtaac atcggtacgg gtattcattt atcacaaaaa 15780
aaacttctct aaatgagtct actgctagaa aacctcatcg aagaagatac catatttttt 15840
gcaggaagta tatctgagta tgatgattta caaatggtta ttgccggcgc aaaatccaaa 15900
tttccaagat ctatgctttc tatttttaat atagtaccta gaacgatgtc aaaatatgag 15960
ttggagttga ttcataacga aaatatcaca ggagcaatgt ttaccacaat gtataatata 16020
agaaacaatt tgggtctagg agatgataaa ctaactattg aagccattga aaactatttc 16080
ttggatccta acaatgaagt tatgcctctt attattaata atacggatat gactgccgtc 16140
attcctaaaa aaagtggtag gagaaagaat aagaacatgg ttatcttccg tcaaggatca 16200
tcacctatct tgtgtatttt cgaaactcgt aaaaagatta atatttataa agaaaatatg 16260
gaatccgcgt cgactgagta tacacctatc ggagacaaca aggctttgat atctaaatat 16320
gcgggaatta atatcctaaa tgtgtattct ccttccacat ccataagatt gaatgccatt 16380
tacggattca ccaataaaaa taaactagag aaacttagta ctaataagga actagaatcg 16440
tatagttcta gccctcttca agaacccatt aggttaaatg attttctggg actattggaa 16500
tgtgttaaaa agaatattcc tctaacagat attccgacaa aggattgatt actataaatg 16560
gagaatgttc ctaatgtata ctttaatcct gtgtttatag agcccacgtt taaacattct 16620
ttattaagtg tttataaaca cagattaata gttttatttg aagtattcgt tgtattcatt 16680
ctaatatatg tattttttag atctgaatta aatatgttct tcatgcctaa acgaaaaata 16740
cccgatccta ttgatagatt acgacgtgct aatctagcgt gtgaagacga taaattaatg 16800
atctatggat taccatggat gacaactcaa acatctgcgt tatcaataaa tagtaaaccg 16860
atagtgtata aagattgtgc aaagcttttg cgatcaataa atggatcaca accagtatct 16920
cttaacgatg ttcttcgcag atgatgattc attttttaag tatttggcta gtcaagatga 16980
tgaatcttca ttatctgata tattgcaaat cactcaatat ctagactttc tgttattatt 17040
attgatccaa tcaaaaaata aattagaagc cgtgggtcat tgttatgaat ctctttcaga 17100
ggaatacaga caattgacaa aattcacaga ctttcaagat tttaaaaaac tgtttaacaa 17160
ggtccctatt gttacagatg gaagggtcaa acttaataaa ggatatttgt tcgactttgt 17220
gattagtttg atgcgattca aaaaagaatc ctctctagct accaccgcaa tagatcctgt 17280
tagatacata gatcctcgtc gcaatatcgc attttctaac gtgatggata tattaaagtc 17340
gaataaagtg aacaataatt aattctttat tgtcatcatg aacggcggac atattcagtt 17400
gataatcggc cccatgtttt caggtaaaag tacagaatta attagacgag ttagacgtta 17460
tcaaatagct caatataaat gcgtgactat aaaatattct aacgataata gatacggaac 17520
gggactatgg acgcatgata agaataattt tgaagcattg gaagcaacta aactatgtga 17580
tgtcttggaa tcaattacag atttctccgt gataggtatc gatgaaggac agttctttcc 17640
agacattgtt gaattctgtg agcgtatggc aaacgaagga aaaatagtta tagtagccgc 17700
actcgatggg acatttcaac gtaaaccgtt taataatatt ttgaatctta ttccattatc 17760
tgaaatggtg gtaaaactaa ctgctgtgtg tatgaaatgc tttaaggagg cttccttttc 17820
taaacgattg ggtgaggaaa ccgagataga aataatagga ggtaatgata tgtatcaatc 17880
ggtgtgtaga aagtgttaca tcgactcata atattatatt ttttatctaa aaaactaaaa 17940
ataaacattg attaaatttt aatataatac ttaaaaatgg atgttgtgtc gttagataaa 18000
ccgtttatgt attttgagga aattgataat gagttagatt acgaaccaga aagtgcaaat 18060
gaggtcgcaa aaaaactgcc gtatcaagga cagttaaaac tattactagg agaattattt 18120
tttcttagta agttacagcg acacggtata ttagatggtg ccaccgtagt gtatatagga 18180
tctgctcccg gtacacatat acgttatttg agagatcatt tctataattt aggagtgatc 18240
atcaaatgga tgctaattga cggccgccat catgatccta ttttaaatgg attgcgtgat 18300
gtgactctag tgactcggtt cgttgatgag gaatatctac gatccatcaa aaaacaactg 18360
catccttcta agattatttt aatttctgat gtgagatcca aacgaggagg aaatgaacct 18420
agtacggcgg atttactaag taattacgct ctacaaaatg tcatgattag tattttaaac 18480
cccgtggcgt ctagtcttaa atggagatgc ccgtttccag atcaatggat caaggacttt 18540
tatatcccac acggtaataa aatgttacaa ccttttgctc cttcatattc agctgaaatg 18600
agattattaa gtatttatac cggtgagaac atgagactga ctcgagttac caaatcagac 18660
gctgtaaatt atgaaaaaaa gatgtactac cttaataaga tcgtccgtaa caaagtagtt 18720
gttaactttg attatcctaa tcaggaatat gactattttc acatgtactt tatgctgagg 18780
accgtgtact gcaataaaac atttcctact actaaagcaa aggtactatt tctacaacaa 18840
tctatatttc gtttcttaaa tattccaaca acatcaactg aaaaagttag tcatgaacca 18900
atacaacgta aaatatctag caaaaattct atgtctaaaa acagaaatag caagagatcc 18960
gtacgcagta ataaatagaa acgtactact gagatatact accgatatag agtataatga 19020
tttagttact ttaataaccg ttagacataa aattgattct atgaaaactg tgtttcaggt 19080
atttaacgaa tcatccataa attatactcc ggttgatgat gattatggag aaccaatcat 19140
tataacatcg tatcttcaaa aaggtcataa caagtttcct gtaaattttc tatacataga 19200
tgtggtaata tctgacttat ttcctagctt tgttagacta gatactacag aaactaatat 19260
agttaatagt gtactacaaa caggcgatgg taaaaagact cttcgtcttc ccaaaatgtt 19320
agagacggaa atagttgtca agattctcta tcgccctaat ataccattaa aaattgttag 19380
atttttccgc aataacatgg taactggagt agagatagcc gatagatctg ttatttcagt 19440
cgctgattaa tcaattagta gagatgagat aagaacatta taataatcaa taatatatct 19500
tatatctcgt ttagaaaaat gctaatatta aaatagctaa cgctagtaat ccaatcggaa 19560
gccatttgat atctataata gggtatctaa tttcctgatt cagatagcgg acagctatat 19620
tctcggtagc tactcgtttg gaatcacaaa cattatttac atctaattta ctatctgtaa 19680
tggaaacgtt tcccaatgaa atggtacaat ccgatacatt gcattttgtt atattttttt 19740
ttaaagaggc tggtaacaac gcatcgcttc gtttacatgg ctcgtaccaa caataatagg 19800
gtaatcttgt atctattcct atccgtacta tgcttttatc aggataaata catttacatc 19860
gtatatcgtc tttgttagca tcacagaatg cataaatttg ttcgtccgtc atgataaaaa 19920
tttaaagtgt aaatataact attattttta tagttgtaat aaaaagggaa atttgattgt 19980
ataccttcgg ttctttaaaa gaaactgact tgataaaaat ggctgtaatc tctaaggtta 20040
cgtatagtct atatgatcaa aaagagatta atgctacaga tattatcatt agtcatgtta 20100
aaaatgacga cgatatcggt accgttaaag atggtagact aggtgctatg gatggggcat 20160
tatgtaagac ttgtgggaaa acggaattgg aatgtttcgg tcactggggt aaagtaagta 20220
tttataaaac tcatatagtt aagcctgaat ttatttcaga aattattcgt ttactgaatc 20280
atatatgtat tcactgcgga ttattgcgtt cacgagaacc gtattccgac gatattaacc 20340
taaaagagtt atcgggacac gctcttagga gattaaagga taaaatatta tccaagaaaa 20400
agtcatgttg gaacagtgaa tgtatgcaac cgtatcaaaa aattactttt tcaaagaaaa 20460
aggtttgttt cgtcaacaag ttggatgata ttaacgttcc taattctctc atctatcaaa 20520
agttaatttc tattcatgaa aagttttggc cattattaga aattcatcaa tatccagcta 20580
acttatttta tacagactac tttcccatcc ctccgttgat tattagaccg gctattagtt 20640
tttggataga tagtataccc aaagaaacca atgaattaac ttacttatta ggtatgatcg 20700
ttaagaattg taacttgaat gctgatgaac aggttatcca gaaggcggta atagaatacg 20760
atgatattaa aattatttct aataacactt ccagtatcaa tttatcatat attacatccg 20820
gcaaaaataa tatgattaga agttatatcg tcgcccgacg aaaagatcag acggctagat 20880
ctgtaattgg tcccagtaca tctatcaccg ttaatgaggt aggaatgccc gcatatatta 20940
gaaatacact tacagaaaag atatttgtta atgcctttac agtggataaa gttaaacaac 21000
tattagcatc aaaccaagtt aaattttact ttaataaacg attaaaccaa ttaacaagaa 21060
tacgccaagg aaagtttatc aaaaataaaa tacatttatt gcctggtgat tgggtagaag 21120
tagctgttca agaatataca agtattattt ttggaagaca gccgtctcta catagataca 21180
acgtcatcgc ttcatctatc agagctaccg aaggagatac tatcaaaata tctcccggaa 21240
ttgccaactc tcaaaatgct gatttcgacg gagatgaaga atggatgata ttagaacaaa 21300
atcctaaagc tgtaattgaa caaagtattc ttatgtatcc gacgacgtta ctcaaacacg 21360
atattcatgg agcccccgtt tatggatcta ttcaagatga aatcgtagca gcgtattcat 21420
tgtttaggat acaagatctt tgtttagatg aagtattgaa catcttgggg aaatatggaa 21480
gagagttcga tcctaaaggt aaatgtaaat tcagcggtaa agatatctat acttacttga 21540
taggtgaaaa gattaattat ccgggtctct taaaggatgg tgaaattatt gcaaacgacg 21600
tagatagtaa ttttgttgtg gctatgaggc atctgtcatt ggctggactc ttatccgatc 21660
ataagtcgaa cgtggaaggt atcaacttta ttatcaagtc atcttatgtt tttaagagat 21720
atctatctat ttacggtttt ggggtgacat tcaaagatct gagaccaaat tcgacgttca 21780
ctaataaatt ggaggccatc aacgtagaaa aaatagaact tatcaaagaa gcatacgcca 21840
aatatctcaa cgatgtaaga gacgggaaaa tagttccatt atctaaagct ttagaggcgg 21900
actatgtgga atccatgtta tccaacttga caaatcttaa tatccgagag atagaagaac 21960
atatgagaca aacgctgata gatgatccag ataataacct cctgaaaatg gccaaagcgg 22020
gttataaagt aaatcctaca gaactaatgt atattctagg tacgtatgga caacaaagga 22080
ttgatggtga accagcagag actcgagtat tgggtagagt cttaccttac tatcttccag 22140
actctaagga tccagaagga agaggttaca ttcttaattc tttaacaaaa ggattaacag 22200
gttctcaata ttacttttcg atgctggttg caagatctca atctactgat atcgtctgtg 22260
aaacatcacg taccggaaca ctggctagaa aaatcattaa aaagatggag gatatggtgg 22320
tcgacggata cggacaagta gttataggta atacgctcat caagtacgcc gccaattata 22380
ccaaaattct aggctcagta tgtaaacctg tagatcttat ctatccagat gagtccatga 22440
cttggtattt ggaaattagt gctctgtgga ataaaataaa acagggattc gtttactctc 22500
agaaacagaa acttgcaaag aagacattgg cgccgtttaa tttcctagta ttcgtcaaac 22560
ccaccactga ggataatgct attaaggtta aggatctgta cgatatgatt cataacgtca 22620
ttgatgatgt gagagagaaa tacttcttta cggtatctaa tatagatttt atggagtata 22680
tattcttgac gcatcttaat ccttctagaa ttagaattac aaaagaaacg gctatcacta 22740
tctttgaaaa gttctatgaa aaactcaatt atactctagg tggtggaact cctattggaa 22800
ttatttctgc acaggtattg tctgagaagt ttacacaaca agccctgtcc agttttcaca 22860
ctactgaaaa aagtggtgcc gtcaaacaaa aacttggttt caacgagttt aataacttga 22920
ctaatttgag taagaataag accgaaatta tcactctggt atccgatgat atctctaaac 22980
ttcaatctgt taagattaat ttcgaatttg tatgtttggg agaattaaat ccagacatca 23040
ctcttcgaaa agaaacagat aggtatgtag tagatataat agtcaataga ttatacatca 23100
agagagcaga aattaccgaa ttagtcgtcg aatatatgat tgaacgattc atctccttta 23160
gcgtcattgt aaaggaatgg ggtatggaaa cattcattga ggacgaggat aatattagat 23220
ttactgtcta tctaaatttc gttgaaccag aggaattgaa tcttagtaag tttatgatgg 23280
ttcttccggg ggcagccaac aagggaaaga ttagtaaatt caagattcct atctctgatt 23340
atacgggtta tgacgacttc aatcaaacaa aaaagctcaa taagatgact gtagaactca 23400
tgaatctaaa agaattaggt tctttcgatt tggaaaacgt caacgtgtat cctggagtat 23460
ggaatacata cgatatcttc ggtatcgagg ccgctcgtga atacttgtgc gaagccatgt 23520
taaacaccta tggagaaggg ttcgattatc tgtatcagcc ttgtgatctt ctcgctagtt 23580
tactatgtgc tagttacgaa ccagaatcag tgaataaatt caagttcggc gcagctagta 23640
ctcttaagag agctacgttc ggagacaata aagcattgtt aaacgcggct cttcataaaa 23700
agtcagaacc tattaacgat aatagtagct gccacttttt tagcaaggtc cctaatatag 23760
gaactggata ttacaaatac tttatcgact tgggtcttct catgagaatg gaaaggaaac 23820
tatctgataa gatatcttct caaaagatca aggaaatgga agaaacagaa gacttttaat 23880
tcttatcaat aacatatttt tctatgatct gtcttttaaa cgatggattt tccacaaatg 23940
cgcctctcaa gtccctcata gaatgataca cgtataaaaa atatagcata ggcaatgact 24000
ccttattttt agacattaga tatgccaaaa tcatagcccc gcttctattt actcccgcag 24060
cacaatgaac caacacgggc tcgtttcgtt gatcacattt agataaaaag gcggttacgt 24120
cgtcaaaata tttactaata tcggtagttg tatcatctac caacggtata tgaataatat 24180
taatattaga gttaggtaat gtatatttat ccatcgtcaa atttaaaaca tatttgaact 24240
taacttcaga tgatggtgca tccatagcat ttttataatt tcccaaatac acattattgg 24300
ttacccttgt cattatagtg ggagatttgg ctctgtgcat atctccagtt gaacgtagta 24360
gtaagtattt atacaaactt ttcttatcca tttataacgt acaaatggat aaaactactt 24420
tatcggtaaa cgcgtgtaat ttagaatacg ttagagaaaa ggctatagta ggcgtacaag 24480
cagccaaaac atcaacactt atattctttg ttattatatt ggcaattagt gcgctattac 24540
tctggtttca gacgtctgat aatccagtct ttaatgaatt aacgagatat atgcgaatta 24600
aaaatacggt taacgattgg aaatcattaa cggatagcaa aacaaaatta gaaagtgata 24660
gaggtagact tctagccgct ggtaaggatg atatattcga attcaaatgt gtggatttcg 24720
gcgcctattt tatagctatg cgattggata agaaaacata tctgccgcaa gctattaggc 24780
gaggtactgg agacgcgtgg atggttaaaa aggcggcaaa ggtcgatcca tctgctcaac 24840
aattttgtca gtatttgata aaacacaagt ctaataatgt tattacttgt ggtaatgaga 24900
tgttaaatga attaggttat agcggttatt ttatgtcacc gcattggtgt tccgatttta 24960
gtaatatgga atagtgttag ataaatgcgg taacgaatgt tcctgtaagg aaccataaca 25020
gtttagattt aacgttaaag atgagcataa acataataaa caaaattaca atcaaaccta 25080
taacattaat atcaaacaat ccaaaaaatg aaatcagtgg agtagtaaac gcgtacataa 25140
ctcctggata acgtttagta gctgccgttc ctattctaga ccaaaaattc ggtttcatgt 25200
tttcgaaacg gtgttctgca acaagtcggg gatcgtgttc tacatatttg gcggcattat 25260
ccagtatctg cctattgatc ttcatttcgt tttcaattct ggctatttca aaataaaatc 25320
ccgatgatag acctccagac tttataattt catctacgat gttcagcgcc gtagtaactc 25380
taataatata ggctgataag ctaacatcat accctcctgt atatgtgaat atggcatgat 25440
ttttgtccat tacaagctcg gttttaactt tattgcctgt aataatttct ctcatctgta 25500
ggatatctat ttttttgtca tgcattgcct tcaagacggg acgaagaaac gtaatatcct 25560
caataacgtt atcgttttct acaataacta catattctac ctttttattt tctaactcgg 25620
taaaaaaatt agaatcccat agggctaaat gtctagcgat atttcttttc gtttcctctg 25680
tacacatagt gttacaaaac cctgaaaaga agtgagtata cttgtcatca tttctaatgt 25740
ttcctccagt ccactgtata aacgcataat ccttgtaatg atctggatca tccttgacta 25800
ccacaacatt tcttttttct ggcataactt cgttgtcctt tacatcatcg aacttctgat 25860
cattaatatg ctcatgaaca ttaggaaatg tttctgatgg aagtctatca ataactggca 25920
caacaataac aggagttttc gccgccgcca tttagttatt gaaattaatc atatacaact 25980
ctttaatacg agttatattt tcgtctatcc attgtttcac atttacatat ttcgacaaaa 26040
agatataaaa tgcgtattcc aatgcttctc tgtttaatga attactaaaa tatacaaaca 26100
cgtcactgtc tggcaataaa tgatatctta gaatattgta acaatttatt ttgtattgca 26160
catgttcgtg atctatgagt tcttcttcga atggcatagg atctccgaat ctgaaaacgt 26220
ataaatagga gttagaataa taatatttga gagtattggt aatatataaa ctctttagcg 26280
gtataattag tttttttctc tcaatttcta tttttagatg tgatggaaaa atgactaatt 26340
ttgtagcatt agtatcatga actctaatca aaatcttaat atcttcgtca cacgttagct 26400
ctttgaagtt tttaagagat gcatcagttg gttcgaccga tggagtaggt gcaacaattt 26460
tttgttcgat gtatgtatgt actggagcca ttgttttaac tataatggtg cttgtatcga 26520
aaaactttaa tgcagatagc ggaagctctt cgccgcgact ttctacatcg taattgggtt 26580
ctaacgccga tctctgaatg gatactagtt ttctaagttc taatgtgatt ctctgaaaat 26640
gtaaatccaa ttcctccggc attatagatg tgtatacatc ggtaaataaa actatagtat 26700
ccaacgatcc cttctcgcaa attctagtct taaccaaaaa atcgtatata accacggaga 26760
tggcgtattt aagagtggat tcttctaccg ttttgttctt ggatgtcata taggaaacta 26820
taaagtccgc actactgtta agaatgatta ctaacgcaac tatatagttc aaattaagca 26880
ttttggaaac ataaaataac tctgtagacg atacttgact ttcgaataag tttgcagaca 26940
aacgaagaaa gaacagacct ctcttaattt cagaagaaaa ctttttttcg tattcctgac 27000
gtctagagtt tatatcaata agaaagttaa gaattagtcg gttaatgttg tatttcatta 27060
cccaagtttg agatttcata atattatcaa aagacatgat aatattaaag ataaagcgct 27120
gactatgaac gaaatagcta tatggttcgc tcaaaaatat agtcttgtta aacgtggaaa 27180
cgataactgt atttttaatc acgtcagcgg catctaaatt aaatataggt atatttattc 27240
cacacactct acaatatgcc acaccatctt cataataaat aaattcgtta gcaaaattat 27300
taattttagt gaaatagtta gcgtcaactt tcatagcttc cttcaatcta atttgatgct 27360
cacacggtgc gaattccact ctaacatccc ttttccatgc ctcaggttca tcgatctcta 27420
taatatctag ttttttgcgt ttcacaaaca caggctcgtc tctcgcgatg agatctgtat 27480
agtaactatg taaatgataa ctagatagaa agatgtagct atatagatga cgatccttta 27540
agagaggtat aataacttta ccccaatcag atagactgtt gttatggtct tcggaaaaag 27600
aatttttata aatttttcca gtattttcca aatatacgta cttaacatct aaaaaatcct 27660
taatgataat aggaatggat aatccgtcta ttttataaag aaatacatat cgcacattat 27720
actttttttt ggaaatggga ataccgatgt gtctacataa atatgcaaag tctaaatatt 27780
ttttagagaa tcttaattgg tccaaattct tttccaagta cggtaataga tttttcatat 27840
tgaacggtat cttcttaatc tctggttcta gttccgcatt aaatgatgaa actaagtcac 27900
tatttttata actaacgatt acatcacctc taacatcatc atttaccaga atactgatct 27960
tcttttgtcg taaatacatg tctaatgtgt taaaaaaaag atcatacaag ttatacgtca 28020
tttcatctgt ggtattcttg tcattgaagg ataaactcgt actaatctct tctttaacag 28080
cctgttcaaa tttatatcct atatacgaaa aaatagcaac cagtgtttga tcatccgcgt 28140
caatattctg ttctatcgta gtgtataaca atcgtatatc ttcttctgtg atagtcgata 28200
cgttataaag gttgataacg aaaatatttt tatttcgtga aataaagtca tcgtaggatt 28260
ttggacttat attcgcgtct agtagatatg cttttatttt tggaatgatc tcaattagaa 28320
tagtctcttt agagtccatt taaagttaca aacaactagg aaattggttt atgatgtata 28380
atttttttag tttttataga ttctttattc tatacttaaa aaatgaaaat aaatacaaag 28440
gttcttgagg gttgtgttaa attgaaagcg agaaataatc ataaattatt tcattatcgc 28500
gatatccgtt aagtttgtat cgtaatggcg tggtcaatta caaataaagc ggatactagt 28560
agcttcacaa agatggctga aatcagagct catctaaaaa atagcgctga aaataaagat 28620
aaaaacgagg atattttccc ggaagatgta ataattccat ctactaagcc caaaaccaaa 28680
cgagccacta ctcctcgtaa accagcggct actaaaagat caaccaaaaa ggaggaagtg 28740
gaagaagaag tagttataga ggaatatcat caaacaactg aaaaaaattc tccatctcct 28800
ggagtcagcg acattgtaga aagcgtggcc gctgtagagc tcgatgatag cgacggggat 28860
gatgaaccta tggtacaagt tgaagctggt aaagtaaatc atagtgctag aagcgatctc 28920
tctgacctaa aggtggctac cgacaatatc gttaaagatc ttaagaaaat tattactaga 28980
atctctgcag tatcgacggt tctagaggat gttcaagcag ctggtatctc tagacaattt 29040
acttctatga ctaaagctat tacaacacta tctgatctag tcaccgaggg aaaatctaaa 29100
gttgttcgta aaaaagttaa aacttgtaag aagtaaatgc gtgcactttt ttataaagat 29160
ggtaaactct ttaccgataa taatttttta aatcctgtat cagacgataa tccagcgtat 29220
gaggttttgc aacatgttaa aattcctact catttaacag atgtagtagt atatgaacaa 29280
acgtgggagg aggcgttaac tagattaatt tttgtgggaa gtgattcaaa aggacgtaga 29340
caatactttt acggaaaaat gcatgtacag aatcgcaacg ctaaaagaga tcgtattttt 29400
gttagagtat ataacgttat gaaacgaatt aattgtttta taaacaaaaa tataaagaaa 29460
tcgtccacag attccaatta tcagttggcg gtttttatgt taatggaaac tatgtttttt 29520
attagatttg gtaaaatgaa atatcttaag gagaatgaaa cagtagggtt attaacacta 29580
aaaaataaac acatagaaat aagtcccgat gaaatagtta tcaagtttgt aggaaaggac 29640
aaagtttcac atgaatttgt tgttcataag tctaatagac tatataagcc gctattgaaa 29700
ctgacggatg attctagtcc cgaagaattt ctgttcaaca aactaagtga acgaaaggta 29760
tatgaatgta tcaaacagtt tggtattaga atcaaggatc tccgaacgta tggagtcaat 29820
tatacgtttt tatataattt ttggacaaat gtaaagtcca tatctcctct tccatcacca 29880
aaaaagttaa tagcgttaac tatcaaacaa actgctgaag tggtaggtca tactccatca 29940
atttcaaaaa gagcttatat ggcaacgact attttagaaa tggtaaagga taaaaatttt 30000
ttagatgtag tatctaaaac tacgttcgat gaattcctat ctatagtcgt agatcacgtt 30060
aaatcatcta cggatggatg atatagatct ttacacaaat aattacaaaa ccgataaatg 30120
gaaatggata agcgtatgaa atctctcgca atgaccgctt tctttgggga gctaagcaca 30180
ttagatatta tggcattgat aatgtctata tttaaacgcc atccaaacaa taccattttt 30240
tcagtggata aggatggtca gtttatgatt gatttcgaat acgataatta taaggcttct 30300
caatatttgg atctgaccct cactccgata tctggagatg aatgcaagac tcacgcatcg 30360
agtatagccg aacaattggc gtgtgtggat attattaaag aggatattag cgaatatatc 30420
aaaactactc cccgtcttaa acgatttata aaaaaatacc gcaatagatc agatactcgc 30480
atcagtcgag atacagaaaa gcttaaaata gctctagcta aaggcataga ttacgaatat 30540
ataaaagacg cttgttaata agtaaatgaa aaaaaactag tcgtttataa taaaacacga 30600
tatggatgcc aacgtagtat catcttctac tattgcgacg tatatagacg ctttagcgaa 30660
gaatgcttcg gaattagaac agaggtctac cgcatacgaa ataaataatg aattggaact 30720
agtatttatt aagccgccat tgattacttt gacaaatgta gtgaatatct ctacgattca 30780
ggaatcgttt attcgattta ccgttactaa taaggaaggt gttaaaatta gaactaagat 30840
tccattatct aaggtacatg gtctagatgt aaaaaatgta cagttagtag atgctataga 30900
taacatagtt tgggaaaaga aatcattagt gacggaaaat cgtcttcaca aagaatgctt 30960
gttgagacta tcgacagagg aacgtcatat atttttggat tacaagaaat atggatcctc 31020
tatccgacta gaattagtca atcttattca agcaaaaaca aaaaacttta cgatagactt 31080
taagctaaaa tattttctag gatccggtgc ccagtctaaa agttctttat tacacgctat 31140
taatcatcca aagtcaaggc ctaatacatc tctggaaata gaatttacac ctagagacaa 31200
tgaaacagtt ccatatgatg aactaataaa ggaattgacg actctctcgc gtcatatatt 31260
tatggcttct ccagagaatg taattctttc tccgcctatt aacgcgccta taaaaacctt 31320
tatgttgcct aaacaagata tagtaggttt ggatctggaa aatctatatg ccgtaactaa 31380
gactgacggc attcctataa ctatcagagt tacatcaaac gggttgtatt gttattttac 31440
acatcttggt tatattatta gatatcctgt taagagaata atagattccg aagtagtagt 31500
ctttggtgag gcagttaagg ataagaactg gaccgtatat ctcattaagc taatagagcc 31560
tgtgaatgca atcaatgata gactagaaga aagtaagtat gttgaatcta aactagtgga 31620
tatttgtgat cggatagtat tcaagtcaaa gaaatacgaa ggtccgttta ctacaactag 31680
tgaagtcgtc gatatgttat ctacatattt accaaagcaa ccagaaggtg ttattctgtt 31740
ctattcaaag ggacctaaat ctaacattga ttttaaaatt aaaaaggaaa atactataga 31800
ccaaactgca aatgtagtat ttaggtacat gtccagtgaa ccaattatct ttggagagtc 31860
gtctatcttt gtagagtata agaaatttag caacgataaa ggctttccta aagaatatgg 31920
ttctggtaag attgtgttat ataacggcgt taattatcta aataatatct attgtttgga 31980
atatattaat acacataatg aagtgggtat taagtccgtg gttgtaccta ttaagtttat 32040
agcagaattc ttagttaatg gagaaatact taaacctaga attgataaaa ccatgaaata 32100
tattaactca gaagattatt atggaaatca acataatatc atagtcgaac atttaagaga 32160
tcaaagcatc aaaataggag atatctttaa cgaggataaa ctatcggatg tgggacatca 32220
atacgccaat aatgataaat ttagattaaa tccagaagtt agttatttta cgaataaacg 32280
aactagagga ccgttgggaa ttttatcaaa ctacgtcaag actcttctta tttctatgta 32340
ttgttccaaa acatttttag acgattccaa caaacgaaag gtattggcga ttgattttgg 32400
aaacggtgct gacctggaaa aatactttta tggagagatt gcgttattgg tagcgacgga 32460
tccggatgct gatgctatag ctagaggaaa tgaaagatac aacaaattaa actctggaat 32520
taaaaccaag tactacaaat ttgactacat tcaggaaact attcgatccg atacatttgt 32580
ctctagtgtc agagaagtat tctattttgg aaagtttaat atcatcgact ggcagtttgc 32640
tatccattat tcttttcatc cgagacatta tgctaccgtc atgaataact tatccgaact 32700
aactgcttct ggaggcaagg tattaatcac taccatggac ggagacaaat tatcaaaatt 32760
aacagataaa aagactttta taattcataa gaatttacct agtagcgaaa actatatgtc 32820
tgtagaaaaa atagctgatg atagaatagt ggtatataat ccatcaacaa tgtctactcc 32880
aatgactgaa tacattatca aaaagaacga tatagtcaga gtgtttaacg aatacggatt 32940
tgttcttgta gataacgttg atttcgctac aattatagaa cgaagtaaaa agtttattaa 33000
tggcgcatct acaatggaag atagaccatc tacaagaaac tttttcgaac taaatagagg 33060
agccattaaa tgtgaaggtt tagatgtcga agacttactt agttactatg ttgtttatgt 33120
cttttctaag cggtaaataa taatatggta tgggttctga tctcccagtt ctaaatgcat 33180
taaataattc caatagagcg atttttgttc ctataggacc ttccaactgt ggatactctg 33240
tattgttaat agatatatta atacttttgt cgggtaacag aggttctacg tcttttaaaa 33300
ataaaagttt gataacatct ggcctgttca taaataaaaa cttggcgatt ctatatatac 33360
tcttattatc aaatctagcc attgtcttat agatgtgagc tactgtaggt gtaccatttg 33420
attttctttc taatactata tatttctctc gaagaagttc ttgcacatca tctgggaata 33480
aaatactact gttgagtaaa tcagttattt tttttatatc gatattgatg gacattttta 33540
tagttaagga taataagtat cccaaagtag ataacgacga taacgaagta tttatacttt 33600
taggaaatca caatgacttt atcagattaa aattaacaaa attaaaggag catgtatttt 33660
tttctgaata tattgtgact ccagatacat atggatcttt atgcgtcgaa ttaaatgggt 33720
ctagttttca gcacggcggt agatatatag aggtggagga atttatagat gctggaagac 33780
aagttagatg gtgttctaca tccaatcata tatctaaaga tatacccgaa gatatgcaca 33840
ctgataaatt tgtcatttat gatatataca cttttgacgc tttcaagaat aaacgattgg 33900
tattcgtaca ggtacctccg tcgttaggag atgatagtca tttgactaat ccgttattgt 33960
ctccgtatta tcgtaattca gtagccagac aaatggtcaa tgatatgatt tttaatcaag 34020
attcattttt aaaatattta ttagaacatc tgattagaag ccactataga gtttctaaac 34080
atataacaat agttagatac aaggataccg aagaattaaa tctaacgaga atatgttata 34140
atagagataa gtttaaggcg tttgtattcg cttggtttaa cggcgtttcg gaaaatgaaa 34200
aggtactaga tacgtataaa aaggtatcta atttgatata atgaattcag tgactgtatc 34260
acacgcgcca tatactatta cttatcacga tgattgggaa ccagtaatga gtcaattggt 34320
agagttttat aacgaagtag ccagttggct gctacgagac gagacgtcgc ctattcctga 34380
taagttcttt atacagttga aacaaccgct tagaaataaa cgagtatgtg tgtgcggtat 34440
agatccgtat ccgaaagatg gaactggtgt accgttcgaa tcaccaaatt ttacaaaaaa 34500
atcaattaag gagatagctt catctatatc tagattaacc ggagtaattg attataaagg 34560
ttataacctt aatataatag acggggttat accctggaat tattacttaa gttgtaaatt 34620
aggagaaaca aaaagtcacg cgatctactg ggataagatt tccaagttac tgctgcagca 34680
tataactaaa cacgttagtg ttctttattg tttgggtaaa acagatttct cgaatatacg 34740
ggccaagtta gaatccccgg taactaccat agtcggatat catccagcgg ctagagaccg 34800
ccaattcgag aaagatagat catttgaaat tatcaacgtt ttactggaat tagacaacaa 34860
ggcacctata aattgggctc aagggtttat ttattaatgc tttagtgaaa ttttaacttg 34920
tgttctaaat ggatgcggct attagaggta atgatgttat ctttgttctt aagactatag 34980
gtgtcccgtc agcgtgcaga caaaatgaag atccaagatt tgtagaagca tttaaatgcg 35040
acgagttaga aagatatatt gagaataatc cagaatgtac actattcgaa agtcttaggg 35100
atgaggaagc atactctata gtcagaattt tcatggatgt agatttagac gcgtgtctag 35160
acgaaataga ttatttaacg gctattcaag attttattat cgaggtgtca aactgtgtag 35220
ctagattcgc gtttacagaa tgcggcgcca ttcatgaaaa tgtaataaaa tccatgagat 35280
ctaatttttc attgactaag tctacaaata gagataaaac aagttttcat attatctttt 35340
tagacacgta taccactatg gatacattga tagctatgaa acgaacacta ttagaattaa 35400
gtagatcatc tgaaaatcca ctaacaagat cgatagacac tgccgtatat aggagaaaaa 35460
caactcttcg ggttgtaggt actaggaaaa atccaaattg cgacactatt catgtaatgc 35520
aaccaccgca tgataatata gaagattacc tattcactta cgtggatatg aacaacaata 35580
gttattactt ttctctacaa caacgattgg aggatttagt tcctgataag ttatgggaac 35640
cagggtttat ttcattcgaa gacgctataa aaagagtttc aaaaatattc attaattcta 35700
taataaactt taatgatctc gatgaaaata attttacaac ggtaccactg gtcatagatt 35760
acgtaacacc ttgtgcatta tgtaaaaaac gatcgcataa acatccgcat caactatcgt 35820
tggaaaatgg tgctattaga atttacaaaa ctggtaatcc acatagttgt aaagttaaaa 35880
ttgttccgtt ggatggtaat aaactgttta atattgcaca aagaatttta gacactaact 35940
ctgttttatt aaccgaacga ggagaccata tagtttggat taataattca tggaaattta 36000
acagcgaaga acccttgata acaaaactaa ttttgtcaat aagacatcaa ctacctaagg 36060
aatattcaag cgaattactc tgtccaagaa aacgaaagac tgtagaagct aacatacgag 36120
acatgttagt agattcagta gagaccgata cctatccgga taaacttccg tttaaaaatg 36180
gtgtattgga cctggtagac ggaatgtttt actctggaga tgatgctaaa aaatatacgt 36240
gtactgtatc aaccggattt aaatttgacg atacaaagtt cgtcgaagac agtccagaaa 36300
tggaagagtt aatgaatatc attaacgata tccaaccatt aacggatgaa aataagaaaa 36360
atagagagct atatgaaaaa acattatcta gttgtttatg cggtgctacc aaaggatgtt 36420
taacattctt ttttggagaa actgcaactg gaaagtcgac aaccaaacgt ttgttaaagt 36480
ctgctatcgg tgacctgttt gttgagacgg gtcaaacaat tttaacagat gtattggata 36540
aaggacctaa tccatttatc gctaacatgc atttgaaaag atctgtattc tgtagcgaac 36600
tacctgattt tgcctgtagt ggatcaaaga aaattagatc tgacaatatt aaaaagttga 36660
cagaaccttg tgtcattgga agaccgtgtt tctccaataa aattaataat agaaaccatg 36720
cgacaatcat tatcgatact aattacaaac ctgtttttga taggatagat aacgcattaa 36780
tgagaagaat tgccgtcgtg cgattcagaa cacacttttc tcaaccttct ggtagagagg 36840
ctgctgaaaa taatgacgcg tacgataaag tcaaactatt agacgagggg ttagatggta 36900
aaatacaaaa taatagatat agattcgcat ttctatactt gttggtgaaa tggtacagaa 36960
aatatcatgt tcctattatg aaactatatc ctacacccga agagattcct gactttgcat 37020
tctatctcaa aataggtact ctgttagtat ctagctctgt aaagcatatt ccattaatga 37080
cggacctctc caaaaaggga tatatattgt acgataatgt ggtcactctt ccgttgacta 37140
ctttccaaca gaaaatatcc aagtatttta attctagact atttggacac gatatagaga 37200
gcttcatcaa tagacataag aaatttgcca atgttagtga tgaatatctg caatatatat 37260
tcatagagga tatttcatct ccgtaaatat atgctcatat atttatagaa gatatcacat 37320
atctaaatga ataccggaat catagattta tttgataatc atgttgatag tataccaact 37380
atattacctc atcagttagc tactctagat tatctagtta gaactatcat agatgagaac 37440
agaagcgtgt tattgttcca tattatggga tcaggtaaaa caataatcgc tttgttgttc 37500
gccttggtag cttccagatt taaaaaggtt tacattctag tgcctaatat caacattttg 37560
aaaattttta attataatat gggtgtagct atgaacttgt ttaatgacga attcatagct 37620
gagaatatct ttattcattc cacaacaagt ttttattctc ttaattataa cgataacgtc 37680
attaattata acggattatc tcgctacaat aactctattt ttatcgttga tgaggcacat 37740
aatatctttg ggaataatac tggagaactt atgaccgtga taaaaaataa aaacaagatt 37800
ccttttctac tattgtctgg atctcccatt actaacacac ctaatactct gggtcatatt 37860
atagatttaa tgtccgaaga gacgatagat tttggtgaga ttattagtcg tggtaagaaa 37920
gtaattcaga cacttcttaa cgaacgcggt gtgaatgtac ttaaggattt gcttaaagga 37980
agaatatcat attacgaaat gcctgataaa gatctaccaa cgataagata tcacggacgt 38040
aagtttctag atactagagt agtatattgt cacatgtcta aacttcaaga gagagattat 38100
atgattacta gacgacagct atgttatcat gaaatgtttg ataaaaatat gtataacgtg 38160
tcaatggcag tattgggaca acttaatctg atgaataatt tagatacttt atttcaggaa 38220
caggataagg aattgtaccc aaatctgaaa ataaataatg gcgtgttata cggagaagaa 38280
ttggtaacgt taaacattag ttccaaattt aaatacttta ttaatcggat acagacactc 38340
aacggaaaac attttatata cttttctaat tctacatatg gcggattggt aattaaatat 38400
atcatgctca gtaatggata ttctgaatat aatggttctc agggaactaa tccacatatg 38460
ataaacggca aaccaaaaac atttgctatc gttactagta aaatgaaatc gtctttagag 38520
gatctattag atgtgtataa ttctcctgaa aacgatgatg gtagtcaatt gatgtttttg 38580
ttttcgtcaa acattatgtc cgaatcctat actctgaaag aggtaaggca tatttggttt 38640
atgactatcc cagatacttt ttctcaatac aaccaaattc ttggacgatc tattagaaaa 38700
ttctcttacg ccgatatttc tgaaccagtt aatgtatatc ttttagccgc cgtatattcc 38760
gatttcaatg acgaagtaac gtcattaaac gattacacac aggatgaatt gattaatgtt 38820
ttaccatttg acatcaaaaa gctgttatat ctaaaattta agactaaaga aacgaataga 38880
atatactcta ttcttcaaga gatgtctgaa acgtattctc ttccaccaca tccatcaatt 38940
gtaaaagttt tattgggaga attggtcaga caattttttt ataataattc tcgtattaag 39000
tataacgact ccaagttact taaaatggtt acatcagtta taaaaaataa agaagacgct 39060
aggaattaca tagatgatat tgtaaacggt cacttctttg tatcgaataa agtatttgat 39120
aaatctcttt tatacaaata cgaaaacgat attattacag taccgtttag actttcctac 39180
gaaccatttg tttggggagt taactttcgt aaagaatata acgtggtatc ttctccataa 39240
aactgatgaa atatataaag aaataaatgt cgagctttgt taccaatgga taccttccag 39300
ttacattgga accacacgag ctgacgttag acataaaaac taatattagg aatgccgtat 39360
ataagacgta tctccataga gaaattagtg gtaaaatggc caagaaaata gaaattcgtg 39420
aagacgtgga attacctctc ggcgaaatag ttaataattc tgtagttata aacgttccgt 39480
gtgtaataac ctacgcgtat tatcacgttg gggatatagt cagaggaaca ttaaacatcg 39540
aagatgaatc aaatgtaact attcaatgtg gagatttaat ctgtaaacta agtagagatt 39600
cgggtactgt atcatttagc gattcaaagt actgcttttt tcgaaatggt aatgcgtatg 39660
acaatggcag cgaagtcact gccgttctaa tggaggctca acaaggtatc gaatctagtt 39720
ttgtttttct cgcgaatatc gtcgactcat aaaaaagaga atagcggtaa gtataaacac 39780
gaatactatg gcaataattg cgaatgtttt attctcttcg atatattttt gataatatga 39840
aaaacatgtc tctctcaaat cggacaacca tctcataaaa tagttctcgc gcgctggaga 39900
ggtagttgct gctcgtataa tctccccaga ataatatact tgcgtgtcgt cgttcaattt 39960
atacggattt ctatagttct ctgttatata atgcggtttt ccatcatgat tagacgacga 40020
caatagtgtt ctgaatttag atagttgatc agaatgaatg tttattggcg ttggaaaaat 40080
tatccataca gcgtctgcag agtggttgat agttgttcct agatatgtaa aataatccaa 40140
cttactaggc agcaaattgt ctagataaaa tactgaatca aacggtgcag acgtattggc 40200
ggatctaatg gaatccaatt gattaactat cttttgaaaa tatacatttt tatgatccaa 40260
tacttgtaag aatatagaaa taatgataag tccatcatcg tgtttttttg cctcttcata 40320
agaactatat tttttcttat tccaatgaac aagattaatc tctccagagt atttgtacac 40380
atctatcaag tgattggatc cataatcgtc ttcctttccc caatatatat gtagtgatga 40440
taacacatat tcattgggga gaaaccctcc acttatatat cctcctttaa aattaatcct 40500
tactagtttt ccagtgttct ggatagtggt tggtttcgac tcattataat gtatgtctaa 40560
cggcttcaat cgcgcgttag aaattgcttt tttagtttct atattaatag gagatagttg 40620
ttgcggcata gtaaaaatga aatgataact gtttaaaaat agctcttagt atgggaatta 40680
caatggatga ggaagtgata tttgaaactc ctagagaatt aatatctatt aaacgaataa 40740
aagatattcc aagatcaaaa gacacgcacg tgtttgctgc gtgtataaca agtgacggat 40800
atccgttaat aggagctaga agaacttcat tcgcgttcca ggcgatatta tctcaacaaa 40860
attcagattc tatctttaga gtatccacta aactattacg gtttatgtac tacaatgaac 40920
taagagaaat ctttagacgg ttgagaaaag gttctatcaa caatatcgat cctcactttg 40980
aagagttaat attattgggt ggtaaactag ataaaaagga atctattaaa gattgtttaa 41040
gaagagaatt aaaagaggaa agtgatgaac gtataacagt aaaagaattc ggaaatgtaa 41100
ttctaaaact tacaacgcgc gataaattat ttaataaagt atatataggt tattgcatgg 41160
cgtgttttat taatcaatcg ttggaggatt tatcgcatac tagtatttac aatgtagaaa 41220
ttagaaagat taaatcatta aatgattgta ttaacgacga taaatacgaa tatctgtctt 41280
atatttataa tatgctagtt aatagtaaat gaacttttac agatctagta taattagtca 41340
gattattaag tataatagac gactagctaa gtctattatt tgcgaggatg actctcaaat 41400
tattacactc acggcattcg ttaaccaatg cctatggtgt cataaacgag tatccgtgtc 41460
cgctatttta ttaactactg ataacaaaat attagtatgt aacagacgag atagttttct 41520
ctattctgaa ataattagaa ctagaaacat gtttagaaag aaacgattat ttctgaatta 41580
ttccaattat ttgaacaaac aggaaagaag tatactatcg tcattttttt ctctagatcc 41640
agctactgct gataatgata gaatagacgc tatttatccg ggtggcatac ccaaaagggg 41700
tgagaatgtt ccagagtgtt tatccaggga aattaaagaa gaagttaata tagacaattc 41760
ttttgtattc atagacactc ggttttttat tcatggcatc atagaagata ccattattaa 41820
taaatttttt gaggtaatct tctttgtcgg aagaatatct ctaacgagtg atcaaatcat 41880
tgatacattt aaaagtaatc atgaaatcaa ggatctaata tttttagatc cgaattcagg 41940
taatggactc caatacgaaa ttgcaaaata tgctctagat actgcaaaac tcaaatgtta 42000
tggccataga ggatgttatt acgaatcatt aaaaaaatta actgaggatg attgattaga 42060
aaatataaat taatttacca tcgtgtattt ttataacggg attgtccggc atatcatgta 42120
gatagttacc gtctacatcg tatactcgac catctacgcc tttaaatcct ctatttattg 42180
acattaatct attagaattg gaataccaaa tattagtacc ctcaattagt ttattggtaa 42240
tatttttgtt agacgataga tcgatggctc ttgaaaccaa ggttttccaa ccggactcat 42300
tgtcgatcgg tgagaagtct ttttcattag catgaatcca ttctaatgat gtatgtttaa 42360
acactctaaa caattggaca aattcttttg atttgctttg aatgatttca aataggtctt 42420
cgtctacagt aggcatacca ttagataatc tagccattat aaagtgcacg tttacatatc 42480
tacgttctgg aggagtaaga acgtgactat tgagacgaat ggctcttcct actatctgac 42540
gaagagacgc ctcgttccat gtcatatcta aaatgaagat atcattgatt gagaagaagc 42600
taataccctc gcctccacta gaagagaata cgcatgtttt aatgcattct ccgttagtgt 42660
ttgattcttg gttaaactca gccaccgcct tgattctagt atcttttgtt ctagatgaga 42720
actctatatt agagatacca aagactttga aatatagtaa taagatttct attcctgact 42780
gattaacaaa tggttcaaag actagacatt taccatggga tgctaatatt cccaaacata 42840
catctataaa tttgacgctt ttctctttta attcagtaaa tagagagata tcagccgcac 42900
tagcatcccc tcccaatagt tctccccttt taaaggtatc taatgcagat ttagaaaatt 42960
ctctatctct taatgaattt ttaaaatcat tatatagtgt tgctatctct tgcgcgtatt 43020
cgcccggatc acgattttgt ctttcaggaa agctatcgaa cgtaaacgta gtagccatac 43080
gtctcagaat tctaaatgat gatatacctg tttttatttc agcgagttta gccttttgat 43140
aaatttcttc ttgctttttc gacatattaa cgtatcgcat taatactgtt ttcttagcga 43200
atgatgcaga cccttctacg tcatcaaaaa tagaaaactc gttattaact atgtacgaac 43260
ataggcctcc tagtttggag actaattctt tttcatcaac tagacgttta ttctcaaata 43320
gcgattggtg ttgtaaggat cctggtcgta gtaagttaac caacatggtg aattcttgca 43380
cactattgac gataggtgta gccgataaac aaatcatctt atggtttttt aatgcgatgg 43440
tcttagataa aaaattatat actgaacgag taggacggat cttaccatct tctttgatta 43500
atgatttaga aatgaagtta tgacattcat caataatgac gcatattcta ctcttggaat 43560
taatagtttt gatattagta aaaaatttat ttctaaaatt ttgatcatcg taattaataa 43620
aaatacaatc cttcgttatc tctggagcgt atctgagtat agtgttcatc caaggatctt 43680
ctatcaaagc ctttttcacc aataagataa tagcccaatt cgtataaata tccttaagat 43740
gtttgagaat atatacagta gtcattgttt taccgacacc cgtttcatgg aacaataaaa 43800
gagaatgcat actgtctaat cctaagaaaa ctcttgctac aaaatgttga taatccttga 43860
ggcgtactac gtccgacccc atcatttcaa caggcatatt agtagttctg cgcaatgcat 43920
aatcgatata ggccgcgtgt gatttactca tttatgagtg ataagtaata actatgtttt 43980
aaaaatcaca gcagtagttt aactagtctt ctctgatgtt tgttttcgat actttttgaa 44040
tcagaagtca tactagaata aagcaacgag tgaacgtaat agagagcttc gtatactcta 44100
ttcgaaaact ctaagaactt attaatgaat tccgtatcca ctggattgtt taaaatacta 44160
aattgaacac tgttcacatc cttccaagaa gaagacttag tgacggactt aacatgagac 44220
ataaataaat ccaaattttt tttacaaaca tcactagcca ccataatggc gctatctttt 44280
aaccagctat cgcttacgca ttttagcagt ctaacatttt taaagagact acaatatatt 44340
ctcatagtat cgattacacc tctaccgaat aaagttggaa gtttaataat acaatatttt 44400
tcgtttacaa aatcaaataa tggtcgaaac acgtcgaagg ttaacatctt ataatcgcta 44460
atgtatagat tgttttcagt gagatgatta ttagatttaa tagcatctcg ttcacgtttg 44520
aacagtttat tgcgtgcgct gaggtcggca actacggcgt ccgctttagt actcctccca 44580
taatacttta cgctattaat ctttaaaatt tcatagactt tatctagatc gctttctggt 44640
aacatgatat catgtgtaaa aagttttaac atgtcggtcg gcattctatt tagatcatta 44700
actctagaaa tctgaagaaa gtaattagct ccgtattcca gactaggtaa tgggctttta 44760
cctagagaca gattaagttc tggcaatgtt tcataaaatg gaagaaggac atgcgttccc 44820
tcccggatat tttttacaat ttcatccatt tacaactcta tagtttgttt tcattattat 44880
tagttattat ctcccataat cttggtaata cttacccctt gatcgtaaga taccttatac 44940
aggtcattac atacaactac caattgtttt tgtacataat agattggatg gttgacatcc 45000
atggtggaat aaactactcg aacagatagt ttatctttcc ccctagatac attagccgta 45060
atagttgtcg gcctaaagaa tatctttggt gtaaagttaa aagttagggt tcttgttcca 45120
ttattgcttt ttgtcagtag ttcattataa attctcgaga tgggtccgtt ctctgaatat 45180
agaacatcat ttccaaatct aacttctagt ctagaaataa tatcggtctt attcttaaaa 45240
tctattccct tgatgaaggg atcgttaatg aacaaatcct tggcctttga ttcggctgat 45300
ctattatctc cgttatagac gttacgttga ctagtccaaa gacttacagg aatagatgta 45360
tcgatgatgt tgatactatg tgatatgtga gcaaagattg ttctcttagt ggcatcacta 45420
tatgttccag taatggcgga aaacttttta gaaatgttat atataaaaga attttttcgt 45480
gttccaaaca ttagcagatt agtatgaaga taaacactca tattatcagg aacattatca 45540
atttttacat acacatcagc atcttgaata gaaacgatac catcttctgg aacctctacg 45600
atctcggcag actccggata accagtcggt ggaccatcgc taacaataac tagatcatcc 45660
aacaatctac tcacatatgc atctatataa tctttttcat cttgtgagta ccctggatac 45720
gaaataaatt tattatccgt atttccataa taaggtttag tataaacaga gagcgatgtt 45780
gccgcatgaa cttcagttac agtcgccgtt ggttggttta tttgacctat tactctccta 45840
ggtttctcta taaatgatgg tttaatttgt acattcttaa ccatatatcc aataaagctc 45900
aattcaggaa cataaacaaa ttctttgttg aacgtttcaa agtcgaacga agagtcacga 45960
ataacgatat cggatactgg attgaaggtt accgttacgg taatttttga atcggatagt 46020
ttaagactgc tgaatgtatc ttccacatca aacggagttt taatataaac gtatactgta 46080
gatggttctt taatagtgtc attaggagtt aggccaatag aaatatcatt aagttcacta 46140
gaatatccag agtgtttcaa agcaattgta ttattgatac aattattata taattcttcg 46200
ccctcaattt cccaaataac accgttacac gaagagatag atacgtgatt aatacattta 46260
tatccaacat atggtacgta accgaatctt cccatacctt taacttctgg aagttccaaa 46320
ctcagaacca aatgattaag cgcagtaata tactgatccc taatttcgaa gctagcgata 46380
gcctgattgt ctggaccatc gtttgtcata actccggata gagaaatata ttgcggcata 46440
tataaagttg gaatttgact atcgactgcg aagacattag accgtttaat agagtcatcc 46500
ccaccgatca aagaattaat gatagtatta ttcattttct atttaaaatg gaaaaagctt 46560
acaataaact ccgtagagaa atatctataa tttgtgagtt ttccttaaag taacagcttc 46620
cgtaaacgcc gtctttatct cttagtaagt ttattgtatt tataaccttt tccttatctt 46680
catagaatac taaaggcaac aaagaaattt ttggttcttc tctaagagct acgtgagact 46740
taaccataga cgccaacgaa tccctacata ttttagaaca gaaataccca acttcaccac 46800
ccttgaatgt ctcaatacta ataggtttaa aaaccaaatc ttgattacaa aaccaacact 46860
tatcaattac actatttgtc ttaatagaca catctgccat agatttataa tactttggta 46920
gtatacaagc gagtgcttct tctttagcgg gcttaaagac tgctttaggt gctgaaataa 46980
ccacatctgg aaggcttact cgcttagcca tttaattacg gaactatttt tttatacttc 47040
taatgagcaa gtagaaaacc tctcatctac aaaaacatac tcgtgtccat aatcctctac 47100
catagttaca cgttttttag atctcatatg tgctaaaaag ttttcccata ctaattggtt 47160
actattattt ttcgtataat ttttaacagt ttgaggtttt agatttttag ttacagaagt 47220
gatatcgaat attttatcca aaaagaatga ataattaatt gtcttagaag gagtgttttc 47280
ttggcaaaag aataccaagt gcttaaatat ttctactact tcattaatct tttctgtact 47340
cagattcagt ttctcatctt ttacttgatt gattatttca aagactaact tataatcctt 47400
tttatttatt ctctcgttag ccttaagaaa actagataca aaatttgcat ctacatcatc 47460
cgtggatatt tgattttttt ccatgatatc caagagttcc gagataattt ctccagaaca 47520
ttgatgagac aataatctcc gcaatacatt tctcaaatga ataagtttat tagacacatg 47580
gaagtttgac tttttttgta cctttgtaca tttttgaaat accgactcgc aaaaaataca 47640
atattcatat ccttgttcag atactatacc gttgtgtcta caaccgctac ataatcgtag 47700
attcatgtta acactctacg tatctcgtcg tccaatattt tatataaaaa cattttattt 47760
ctagacgttg ccagaaaatc ctgtaatatt tttagttttt tgggctgtga ataaagtatc 47820
gccctaatat tgttaccgtc ttccgccaat atagtagtta aattatccgc acatgcaaaa 47880
gaacaccgct taggcggatt cagtacaatg ttatattttt cgtaccaact catttaaata 47940
tcataatcta aaatagttct gtaatatgtc tagcgctaat atattgatca taatcctgtg 48000
cataaattaa gatacaacaa tgtctcgaaa tcatcgacat ggcttcttcc atagttagaa 48060
gatcgtcgtc aaagttagca acgtgattca tcaacatttg ctgttttgag gcagcaaata 48120
ctgaaccgtc gccattcaac cattcataaa aaccatcgtc tgaatccatt gataatttct 48180
tgtactggtt tttgagagct cgcatcaatc tagcatttct agctcccgga ttgaaaacag 48240
aaagaggatc gtacatccag ggtccatttt ctgtaaatag aatcgtataa tgtcccttca 48300
agaagatatc agacgatcca caatcaaaga attggtctcc gagtttgtaa caaactgcgg 48360
actttaacct atacatgata ccgtttagca tgatttctgg tgatacgtca atcggagtat 48420
catctattag agatctaaag ccggtgtaac attctccacc aaacatattc ttattctgac 48480
gtcgttctac ataaaacatc attgctccat taacgataac aggggaatga acagcactac 48540
ccatcacatt agttcccaat ggatcaatgt gtgtaactcc agaacatctt ccatatccta 48600
tgttaggagg agcgaacacc actcttccac tattgccatc gaatgccata gaataaatat 48660
ccttggaatt gatagaaatc ggactgtcgg atgttgtgat catcttcata ggattaacaa 48720
ctatgtatgg tgccgcctga agtttcatat cgtaactgat gccgtttata ggtctagcca 48780
cagaaaccaa cgtaggtcta aatccaacta tagacaaaat agaagccaat atctgttcct 48840
catctgtcat aacttgagag catccagtat gaataatctt cattagatgg ggatctaccg 48900
catcatcatc gttacaataa aaaattccca ttctaatgtt cataattgct tttctaatca 48960
tggtatgcat gtttgctctc tgaatctctg tggaaattag atctgataca cctgtaatca 49020
ctatcggatt atcctccgta agacgattaa ccaacaacat ataattataa gactttactt 49080
ttctaaattc ataaagttgc tggattaggc tataggtgtc tccatgtaca tacgcgttct 49140
cgagcgcagg aagtttaata ccgaatagtg ccatcagaat aggatgaata tagtaattag 49200
tttctggttt tctataaata aaagacaaat cttgtgaact agacatatcg gtaaaatgca 49260
tggattggaa tcgtgtagtc gacagaagaa tatgatgatt agatggagag tatattttat 49320
ctaactcttt gagttggtca ccgattctag gactagctcg agaatgaata agtactaaag 49380
gatgagtaca tttcacagaa acactagcat tgttcaatgt gctctttaca tgggtaagga 49440
gttgaaatag ctcgtttcta tttgttctga caatatttag tttattcata atgttaagca 49500
tatcctgaat agtaaagtta gatgtgtcat acttgttagt agttagatat ttagcaattg 49560
cattcccatc atttctcaat ctcgtactcc aatcatgtgt agatgctact tcgtcgatgg 49620
aaaccataca atcctttttg ataggctgtt gagattgatt atttcctgca cgtttaggtt 49680
tggtacgttg atttctagcc cctgcggata taaagtcatc gtctacaatt tgggacaatg 49740
aattgcatac actacaagac aaagatttat cagaagtgtg aatatgatct tcatctacca 49800
aagaaagagt ttgattagta taactagatt ttagtcctgc gttagatgtt aaaaaaacat 49860
cgctattgac cacggcttcc attatttata ttcgtagttt ttactcgaaa gcgtgatttt 49920
aatatccaat cttattactt ttggaatcgt tcaaaacctt tgactagttg tagaatttga 49980
tctattgccc tacgcgtata ctcccttgca tcatatacgt tcgtcaccag atcgtttgtt 50040
tcggcctgaa gttggtgcat atctctttca acattcgaca tgagatcctt aagggccata 50100
tcgtctagat tttgttgaga tgctgctcct ggatttggat tttgttgtgc tgttgtacat 50160
actgtaccac cagtaggtgt aggagtacat acagtggcca caataggagg ttgaggaggt 50220
gtaaccgttg gagtagtaca agaaatattt ccatccgatt gttgtgtaca tgtagttgtt 50280
ggtaacgtct gagaaggttg ggtagatggc ggtgtcgtcg tcttttgatc tttattaaat 50340
ttagagataa tatcctgaac agcattgctc ggcgtcaacg ctggaaggag tgaactcgcc 50400
ggcgcatcag tatcttcaga cagccaatca aaaagattag acatatcaga tgatgtatta 50460
gtttgttgtc gtggttttgg tgtaggaaca gtactactag gtagaagaat aggagccggt 50520
gtagctgttg gaaccggctg tggagttata tgaatagttg gttgtagcgg ttggataggc 50580
tgtctgctgg cgaccgtcat attatctcta gctagttgtt ctcgcaactg tctttgataa 50640
tacgactctt gagactttag tcctatttca atcgcttcat cctttttcgt atccggatcc 50700
ttttcttcag aataatagat tgacgacttt ggtgtagagg attctgccag cccctgtgag 50760
aacttgttaa agaagtccat ttaaggcttt aaaattgaat tgcgattata agattaaatg 50820
gcagacacag acgatattat cgactatgaa tccgatgatc tcaccgaata cgaggatgat 50880
gaagaagagg aagaagatgg agagtcacta gaaactagtg atatagatcc caaatcttct 50940
tataagattg tagaatcagc atccactcat atagaagatg cgcattccaa tcttaaacat 51000
atagggaatc atatatctgc tcttaaacga cgctatacta gacgtataag tctatttgaa 51060
atagcgggta taatagcaga aagctataac ttgcttcaac gaggaagatt acctctagtt 51120
tcagaatttt ctgacgaaac gatgaagcaa aatatgctac atgtaattat acaagagata 51180
gaggagggtt cttgtcctat agtcatcgaa aagaacggag aattgttgtc ggtaaacgat 51240
tttgacaaag atggtctaaa attccatcta gactatatta tcaaaatttg gaaacttcaa 51300
aaacgatatt agaatttata cgaatatcgt tctctaaatg tcacaatcaa gtctcgcatg 51360
ttcagcaatt tattgtcgta ctttatatcg tgttcattaa cgatatcttg caaaatagta 51420
atgattctat cttccttcga tagatattct tcagagatta ttgtcttata ttttttcttg 51480
ttatccgata tgaatttgat aagactttga acattattga tacccgtctg tttaattttt 51540
tctacagata ttttagtttt ggcagattct atcgtatctg tcaatagaca tccaacatcg 51600
acattcgacg tcaattgtct ataaatcaac gtataaattt tagaaataac attagcgaat 51660
tgttgtgcat tgatgtcgtt attctgaaac agtatgattt taggtagcat tttcttaaca 51720
aagagaacgt atttattgtt actcagttga acagatgata tatccagatt actaacgcat 51780
ctgattccgt ataccaaact ttcagaagaa atggtgtaca attgtttgta ttcattcaat 51840
gtctcttttt cagaaattag tttagagtcg aatactgcaa taattttcaa gagatagttt 51900
tcatcagata agattttatt tagtgtagat atgataaaac tattgttttg ttggagaact 51960
tgatacgccg cgttctctgt agtcgacgct ctcaaatggg aaacaatctc cattattttt 52020
ttggaatcgg atactatatc ttcggtatct tgacgcagtc tagtatacat agagttaaga 52080
gagattagag tttgtacatt aagcaacatg tctctaaatg tggctacaaa cttttccttt 52140
ttcacataat ctagtttatt atataccgat ttcacaacgg caccagattt aaggaaccag 52200
aatgaaaaac tctgataact acaatatttc atcatagtta cgattttatc atcttctata 52260
gttggtgtaa tagcgcatac ctttttctcc aagactggaa ccaacgtcat aaaaatgttt 52320
aaatcaaaat ccatatcaac atctgatgcg ctaagaccag tctcgcgttc aagattatct 52380
ttactaatgg tgacgaactc atcatataga actctaagtt tgtccattat ttatttacag 52440
atttagttgt ttaatttatt tgtgctcttc cagagttggg atagtatttt tctaacgtcg 52500
gtattatatt attaggatct acgttcatat gtatcataat attaatcatc cacgttttga 52560
taaatctatc tttagcttct gaaataacgt atttaaacaa aggagaaaaa tatttagcta 52620
cggcatcaga cgcaataaca ttttttgtaa atgtaacgta tttagacgac agatcttcgt 52680
taaaaagttt tccatctatg tagaatccat cggttgttaa caccattccc gcgtcagatt 52740
gaataggagt ttgaatagtt tgttttggaa atagatcctt caataactta tagttgggtg 52800
ggaaaaaatc gattttatca ctagactctt tcttttttac tatcattacc tcatgaacta 52860
tttcttgaat gagtatatgt attttctttc ctatatcgga cgcgttcatt ggaaaatata 52920
ccatgtcgtt aactataaga atatttttat cctcgtttac aaactgaata atatcagatg 52980
tagttcgtaa acgaactata tcatcaccag cacaacatct aactatatga tatccactag 53040
tttcctttag ccgtttatta tcttgttcca tattagcagt cattccatca tttaagaagg 53100
cgtcaaagat aatagggaga aatgacattt tggattctgt tacgacttta ccaaaattaa 53160
ggatatacgg acttactatc tttttctcaa cgtcgatttg atgaacacac gatgaaaatg 53220
tgcttctatg agattgatca tgtagaaaac aacaagggat acaatatttc cgcatatcat 53280
gaaatatatt aagaaatccc accttattat atttccccaa aggatccatg catgtaaaca 53340
ttatgccgtt atcattaata aagacttctt tctcatcgga tttgtaaaag ttgttactga 53400
tttttttcat tccaggatct agataattaa taatgatggg ttttctattc ttattctttg 53460
tattttggca tatcctagac cagtaaacag tttccacttt ggtaaaatca gcagactttt 53520
gaacgctatt aaacatggca ttaatggcaa taactaaaaa tgtaaaatat ttttctatgt 53580
taggaatatg gtttttcact ttaatagata tatggttttt ggccaaaatg atagatattt 53640
ttttatccga ggatagtaaa atattattag tcgccgtctc tataaaaatg aagctagtct 53700
cgatatccaa ttttattcta gaattgatag gagtcgccaa atgtacctta tacgttatat 53760
ctcccttgat gcgttccatt tgtgtatcta tatcggacac aagatctgta aatagtttta 53820
cgttattaat catcacggta tcgccgtcgc tagataacgc taatgtacca tccaagtccc 53880
aaatggagag atttaactgt tcatcgttta gaataaaatg attaccggtc atattaataa 53940
agtgttcatc gtatctagat aacaacgact tataattaat gtccaagtct tgaactcgct 54000
gaatgatctt ttttaaccca gttagtttta gattggtacg aaatatattg ttaaactttg 54060
attctacagt aatgtccaaa tctagttgtg gaaatacttc catcaacatt gtttcaaact 54120
tgataatatt attatctaca tcttcatacg atccaaattc cggaatagat gtatcacatg 54180
ctcttgccac ccagataacc aaaaagtcac acgctccagg atatacattg tataaaaagc 54240
tatcgttttt tagtagtgtt tttttctgag tatatacgaa gggattaaaa atagtattat 54300
caacgtaact atattccaaa ttattcttat gagaatagat aataatatcg tccttaatat 54360
ctaacaaatt tcctaaatat ccctttaatt gagtcattcg aagcgtcaat agaatatgtc 54420
tcttaactat ttccggctgt tgtatattta aatgacttcg taaaaaataa tatatgggcg 54480
acttctcatc tatgtaatca tatggagtga gatatagggc tcgttctacc tcctgcccct 54540
tacccacctg taataccaat tgcggactta ctatatatcg catatttata tcgtggggta 54600
aagtgaaaat ctactaccga tgatgtaagt cttacaatgt tcgaaccagt accagatctt 54660
aatttggagg cctccgtaga actaggggag gtaaatatag atcaaacaac acctatgata 54720
aaggaaaata gcggttttat atcccgtagt agacgtctat tcgcccatag atctaaggat 54780
gatgagagaa aactagcact acgattcttt ttacaaagac tttatttttt agatcataga 54840
gagattcatt atttgttcag atgcgttgac gctgtaaaag acgtcactat taccaaaaaa 54900
aataacatta tcgtggcgcc ttatatagca cttttaacta tcgcatcaaa aggatgcaaa 54960
cttacagaaa caatgattga agcatttttt ccagaactat ataatgaaca tagtaagaaa 55020
tttaaattca actctcaagt atccatcatc caagaaaaac tcggatacca gtttggaaac 55080
tatcacgttt atgattttga accgtattac tctacagtag ctctggctat tcgagatgaa 55140
cattcatctg gcatttttaa tatccgtcaa gagagttatc tggtaagttc attatctgaa 55200
ataacatata gattttatct aattaatcta aaatctgatc ttgttcaatg gagtgctagt 55260
acgggcgctg taattaatca aatggtaaat actgtattga ttacagtgta tgaaaagtta 55320
caactggtca tagaaaatga ttcacaattt acatgttcat tggctgtgga atcaaaactt 55380
ccaataaaat tacttaaaga tagaaatgaa ttatttacaa aattcattaa cgagttaaaa 55440
aagaccagtt cattcaagat aagcaaacgc gataaggata cgctactaaa atattttact 55500
taggactgga gttagaattt atagacgact catttcgttt atcattgtta ctattattac 55560
tattactatc attattagtg ttggcattat tagtattctt cttgtcatct tgttcagaaa 55620
tatacagcaa tgctatacct aatactaaat acattatcat gctcgcaatg gctctaacaa 55680
caacgaacca aaatgaattt ggtcgtagct tttgttcaca aaaatacata aagaaatgtc 55740
tacataaatc tatggcgcca ttggctactt gaaatagcgc cagtcctcct acagatttta 55800
atatagctgt ataacatgac atttattcat catcaaaaga gacagagtca ccatctgtca 55860
tatttagatt ttttttcatg tgttcaaagt atcctctact catttcatta taatagttta 55920
tcatacttag aattttagga cggatcaatg agtaagactt gactagatcg tcagtagtaa 55980
tttgtgcatc gtctattctg catccgcttc gtcgaataat gtatagcatc gctttgagat 56040
tctccatagc tatcaagtct ttatacaatg acatggaaat atctgtgaat actttatact 56100
tctccaacat cgatgcctta acatcatcgc ctactttagc attgaaaata cgttctattg 56160
tgtagatgga tgtagcaaga tttttaaaca acaatgccat cttacacgat gattgcctca 56220
agtctccaat cttttgttta gaacgattag ctacagagtt caacgcttgg ctgactagca 56280
tattattatc tttagaaatt gtattcttca atgaggcgtt tatcatatct gtgatttcgt 56340
tagtcatatt acagtctgac tgggttgtaa tgttatccaa catatcacct atggatacgg 56400
tacacgtacc agcatttgta ataatcctat ctaagatgtt gtatggcatt gcgcagaaaa 56460
tatcttctcc tgtaatatct ccactctcga taaatctact cagattattc ttaaatgcct 56520
tattctctgg agaaaagata tcagtgtcca tcatttcatt aatagtatac gcagaaaaga 56580
taccacgagt atcaattcta tccaagatac ttatcggttc cgagtcacag ataatggttt 56640
cctctccttc gggagatcct gcatagaaat atctaggaca atagtttcta tactgtctgt 56700
aactctgata atctctaaag tcactaactg ataccatgaa attgagaaga tcaaacgctg 56760
aagtaatcaa tttttctgcc tcgtttttac tacaactagt tttcatcaat gtagcgacga 56820
tgtattgttt agttactctt ggtctaatac tgatgataga gatattattg cttcccataa 56880
tggatcttct agtagtcacc ttaaagccca ttgatgcgaa tagcagatag ataaagtctt 56940
ggtatgactc ctttctaata tagtacggac tacctttgtc acccaacttt atacccacat 57000
aagccataac aacctcttta atagccgttt catgaggttt atcagccatg agcctgagta 57060
gttggaagaa tctcatgaat cccgtctcag aaagtcctat atgcatgata gatttatctt 57120
tcctgggaaa ctctcgtata gtcatagatg aaatactctt caaagtttct gaaataagat 57180
tagtaacagt cttacctccg actactctgg gtaacaaaca tactctaata ggtgttttct 57240
ctgcggagat aatatcagaa aggatagagc aataagtagt attattgtga ttataaagac 57300
cgaatacata acaggtagaa tttataaaca tcatgtcctg aaggttttta gacttgtatt 57360
cctcgtaatc cataccgtcc caaaacatgg atttggtaac tttgatagcc gtagatcttt 57420
gttccttcgc caacaggtta aagaaattaa taaagaattt gttgtttcta tttatgtcca 57480
caaattgcac gtttggaagc gccacggtta cattcactgc agcattttga ggatcgcgag 57540
tatgaagtac gatgttattg tttactggta tatctggaaa gaaatctacc agtctaggaa 57600
taagagattg atatcgcata gaaatagtaa agtttataat ctcatcatcg aagagcattt 57660
tgttaccatt gtaataaata tccactctgt catatgtata aatgaagtac tgttcaaaca 57720
tgatgagatg tttatatgtt ggcatagtag tgagatcgac gtttggtaat ggcaatgtat 57780
taagattaac tccataatgt ctagcagcat ctgcgatgtt ataagcgtcg tcaaagcggg 57840
gtcgatcttg tattgttata tattgtctaa cacctataag attatcaaaa tcttgtctgc 57900
ttaatacacc gttaacaatt tttgccttga attcttttat tggtgcatta ataacatcct 57960
tatagaggat gttaaacaaa taagtgttat caaagttaag atctggatat ttcttttctg 58020
ctagaacatc cattgagtcg gagccatctg gtttaatata accaccgata aatctagctc 58080
tgtattctgt atccgtcaat ctaatattaa gaaggtgttg agtgaaaggt ggaagatcgt 58140
aaaagctgtg agtattaatg ataggattag tttccgaact aatgttaatt ggggtattaa 58200
taatatctat atttccagcg ttaagtgtaa cattaaacag ttttaattca cgtgacgtgg 58260
tatcaattaa ataattaatg cccaatttgg atatagcagc ctgaagctca tcttgtttag 58320
ttacggatcc taatgagtta ttaagcaata tatcgaacgg atgaacgaag gttgttttaa 58380
gttggtcaca tactttgtaa tctagacata gatgcggaag aacggtagaa actatacgaa 58440
ataaatattc agagtcctct aattgatcaa gagtaactat tgacttaata ggcatcattt 58500
atttagtatt aaatgacgac cgtaccagtg acggatatac aaaacgattt aattacagag 58560
ttttcagaag ataattatcc atctaacaaa aattatgaaa taactcttcg tcaaatgtct 58620
attctaactc acgttaacaa cgtggtagat agagaacata atgccgccgt agtgtcatct 58680
ccagaggaaa tatcctcaca acttaatgaa gatctatttc cagatgatga ttcaccggcc 58740
actattatcg aacgagtaca acctcatact actattattg acgatactcc acctcctact 58800
tttcgtagag agttattgat atcggaacaa cgtcaacaac gagaaaaaag atttaatatt 58860
acagtatcga aaaatgctga agcaataatg gaatctagat ctatgataac ttctatgcca 58920
acacaaacac catccttggg agtagtttat gataaagata aaagaattca gatgttggag 58980
gatgaagtgg ttaatcttag aaatcaacga tctaatacaa aatcatctga taatttagat 59040
aattttacca aaatactatt tggtaagact ccgtataaat caacagaagt taataagcgt 59100
atagccatcg ttaattatgc aaatttgaac gggtctccct tatcagtcga ggacttggat 59160
gtttgttcag aggatgaaat agatagaatc tataaaacga ttaaacaata tcacgaaagt 59220
agaaaacaaa aaattatcgt cactaacgtg attattattg tcataaacat tatcgagcaa 59280
gcattgctaa aactcggatt tgaagaaatc aaaggactga gtaccgatat cacttcagaa 59340
attatcgatg tggagatcgg agatgactgc gatgctgtag catcaaaact aggaatcggt 59400
aacagtccgg ttcttaatat tgtattgttt atactcaaga tattcgttaa acgaattaaa 59460
attatttaat ttaatacatt cccatatcca gacaacaatc gtctggatta atctgttcct 59520
gtcgtctcat accggacgac atattaatct ttttattagt aggcatcttt ttagatggtt 59580
tctttttccc agcattaact gagtcgatac ctagaagatc gtgattgatc tctccgacca 59640
ttccacgaac ttctaattgg ccgtctctaa cggtaccata aactatttta ccagcattag 59700
taacagcttg gacaatctga ccatccatcg cattgtacga tgtagtagta actgttgttc 59760
tacgtctagg agcaccagaa gtatttttgg agcccttgga ggctgatgta gaagaagacg 59820
aggattttga ttttggttta catgtaatac attttgaact ctttgatttt gtatcacatg 59880
cgccggcagt cacatctgtt tgagaattaa gattattgtt gcctcctttg acggctgcat 59940
ctccaccgat ttgcgctagt agatttttaa gctgtggtgt aatcttatta actgtttcga 60000
tataatcatc gtaactgctt ctaacggcta aatttttttt atccgccatt tagaagctaa 60060
aaatattttt atttatacag aagatttaac tagattatac aatgaactaa tatgatcctt 60120
ttccagatta tttacaaact tggtattttt tggttctgga ggaggcgaat ttaaattcgg 60180
acttggattc ggattttgtg agttcttgat cttattatac atcgagtata ggatggcgac 60240
ggtaactgct acacaaatac cgatcaacaa aagaatacca atcatttatt gacaataact 60300
tcactattga tcaagtatgc aatatatcat cttttcacta aataagtagt aataatgatt 60360
caacaatgtc gagatatatg gacgataata atttagttca tggaaatatc gctatgattg 60420
gtatgaatga ctccgctaac tctgtggggc gcgcagtgct ttccccacat agaataaatt 60480
agcattccga ctgtgataat aataccaagt ataaacgcca taatactcaa tactttccat 60540
gtacgagtgg gactggtaga cttactaaag tcaataaagg cgaagataca cgaaagaatc 60600
aaaagaatga ttccagcgat tagcacgccg gaaaaataat ttccaatcat aagcatcatg 60660
tccatttaac taataaaaat tttaaatcgc cgaatgaaca aagtggaata taaaccatat 60720
aaaaacaata gtttgtactg caaaaataat atctattttt gttttcgaag atatggtaaa 60780
attaaatagt agtacacagc atgttataac taacagcagc aacggctcgt aattacttat 60840
catttactag acgaaaaggt ggtgggatat tttcttgctc aaataatacg aatatatcac 60900
ccatccattt tatgcgatgt ttatatactc taatctttaa tagatctata gacgacgggt 60960
ttaccaacaa tatagatttt atcgattcat ctaatttaaa cccttcctta aacgtgaatg 61020
atctattatc tggcataacg atgaccctac ctgatgaatc ggacaatgta ctgggccatg 61080
tagaataaat tatcaacgaa ttatcgtcta cgaacattta tatcatttgt tttaatttta 61140
ggacgcgaat aaatagatat aaaatagaaa ataacagata ttacaaccag tgttatggcc 61200
gcgcccaacc aggtaggcag ttttatttta tcttttacta caggttctcc tggatgtacg 61260
tcaccaacgg cggacgtagt tctagtacaa ttagacgtaa gttccgcttg ggaatttttt 61320
aacgctaaag agttaacgtt aatcgtgcac ccaacgtatt tacatctagt tctttgaaca 61380
tcttgattat aatataacca ttttctatct ctagattcgt cggtgcactc atgtaaccaa 61440
cataccctag gtcctaaata tttatctccg gaattagatt ttggataatt cgcgcaccaa 61500
caatttctat ttcctttatg atcgttacaa aagacgtata atgccgtatc cccaaaagta 61560
aaataatcag gacgaataat tctaataaac tcagaacaat atctcgcatc catatgtttg 61620
gagcaaatat cggaataagt agacatagcc ggtttccgtt ttgcacgtaa ccattctaaa 61680
caattggggt ttccaggatc gtttctacaa aatccagtca tgaaatcgtc acaatgttct 61740
gtcttgtaat tattattaaa tatttttgga cagtgtttgg tatttgtctt agaacaacat 61800
tttgccacgc tatcactatc gcccaggaga taatcctttt ttataaaatg acatcgttgc 61860
ccggatgcta tataatcagt agcgtgtttt aaatccttaa tatattcagg agttacctcg 61920
ttctgataat agattaatga tccaggacga aatttgaaag aactacatgg ttctccatga 61980
attaatacat attgtttagc aaattcagga actataaaac tactacaatg atctatcgac 62040
ataccatcta tcaaacaaaa cttgggttta atttctcccg gagatgtttc ataatagtac 62100
gtataacttt cttctgcaaa cttaacagct ctattatatt caggataatt aaaacctaat 62160
tccatatatt tgtctcgtat atctgctatt cctggtgcta ttttgattct attaagagta 62220
acagctgccc ccattcttaa taatcgtcag tatttaaact gttaaatgtt ggtatatcaa 62280
catctacctt atttcccgca gtataaggtt tgttgcaggt atactgttca ggaatggtta 62340
catttatact tcttctatag tcctgtcttt cgatgttcat cacatatgca aagaacagaa 62400
taaacaaaat aatgtaagaa ataatattaa atatctgtga attcgtaaat acattgattg 62460
ccataataat tacagcagct acaatacaca caatagacat tcccacagtg ttgccattac 62520
ctccacgata catttgagtt actaagcaat aggtaataac taagctagta agaggcaata 62580
gaaaagatga gataaatatc atcaatatag agattagagg agggctatat agagccaaga 62640
cgaacaaaat caaaccgagt aacgttctaa catcattatt tttgaagatt cccaaataat 62700
cattcattcc tccataatcg ttttgcatca tacctccatc tttaggcata aacgattgct 62760
gctgttcctc tgtaaataaa tctttatcaa gcactccagc acccgcagag aagtcgtcaa 62820
gcatattgta atatcttaaa taactcattt atatattaaa aaatgtcact attaaagatg 62880
gagtataatc tttatgccga actaaaaaaa atgacttgtg gtcaacccct aagtcttttt 62940
aacgaagacg gggatttcgt agaagttgaa ccgggatcat cctttaagtt tctgatacct 63000
aagggatttt acgcctctcc ttccgtaaag acgagtctag tatttgaaac attaacaacg 63060
accgataata aaatcactag tatcaatcca acaaatgcgc caaagttata tcctcttcaa 63120
cgcaaagtcg tatctgaagt agtttctaat atgaggaaaa tgatcgaatc aaaacgtcct 63180
ctatacatta ctcttcactt ggcgtgtgga tttggtaaga ctattaccac gtgttatctt 63240
atggctacac acggtagaaa aaccgtcatt tgcgtaccca ataaaatgtt aatacatcaa 63300
tggaagacac aggtagaggc agtcggattg gaacataaga tatccataga tggagtaagt 63360
agtctattaa aggaactaaa gactcaaagt ccggatgtat taatagtagt cagtagacat 63420
ctgacaaacg atgccttttg taaatatatc aataagcatt atgatttgtt catcttggat 63480
gaatcacata cgtataatct gatgaacaat acagcagtta caagattttt agcgtattat 63540
cctccgatga tgtgttattt tttaactgct acacctagac cagctaaccg aatttattgt 63600
aacagtatta ttaatattgc caagttatcc gatctaaaaa aaactatcta tgcggtagat 63660
agtttttttg agccatattc cacagacaat attagacata tggtaaaacg actagatgga 63720
ccatctaata aatatcatat atataccgag aagttattat ctgtagacga gcctagaaat 63780
caacttattc ttaataccct ggtagaagaa ttcaagtcag gaactattaa tcgcatttta 63840
gttattacta aactacgtga acatatggta ttattctaca aacgattatt agatcttttc 63900
ggaccagagg ttgtatttat aggagacgcc caaaatagac gtactccaga tatggtcaaa 63960
tcaatcaagg aactaaatag atttatattc gtatccacct tattttattc cggtactggt 64020
ttagatattc ctagtttgga ttcgttgttc atttgctcgg cagtaatcaa caatatgcaa 64080
atagagcaat tactagggag ggtatgtcga gaaacagaac tattagatag gacggtatat 64140
gtatttccta acacatccat caaagaaata aagtacatga taggaaattt catgcaacga 64200
attattagtc tgtctgtaga taaactagga tttaaacaag aaagttatcg gaaacatcaa 64260
gaatccgatc ccacttctgt atgtacaaca tcctccagag aagaacgtgt attaaataga 64320
atatttaact cgcaaaatcg ttaagaagtt taagcgacga tccgcatgct gcgcaggcca 64380
gtgtattacc cctcatagta ttaatataat ccaatgatac ttttgtgatg tcggaaatct 64440
taaccaattt agactgacag gcagaacacg tcatgcaatc atcatcgtca tcgataactg 64500
tagtcttggg cttctttttg cggctcttca ttccggaacg cacattggtg ctatccattt 64560
aggtagtaaa aaataagtca gaatatgccc tataacacga tcgtgcaaaa cctggtatat 64620
cgtctctatc tttatcacaa tatagtgtat cgacatcttt attattattg acctcgttta 64680
tcttggaaca tggaatggga acatttttgt tatcaacggc cacctttgcc ttaattccag 64740
atgttgtaaa attataacta aacagtctat catcgacaca aatgaaattc ttgtttagac 64800
gtttgtagtt tacgtatgcg gctcgttcgc gtctcatttt ttcagatatt gcaggtacta 64860
taatattaaa aataagaatg aaataacata ggattaaaaa taaagttatc atgacttcta 64920
gcgctgattt aactaactta aaagaattac ttagtctgta caaaagtttg aaattttcag 64980
attctgcggc tatagaaaag tataattctt tggtagaatg gggaacatct acttactgga 65040
aaataggcgt gcaaaaggta gctaatgtcg agacgtcaat atctgattat tatgatgagg 65100
taaaaaataa accgtttaat attgatccgg gctattacat tttcttaccg gtatattttg 65160
ggagcgtctt tatttattcg aagggtaaaa atatggtaga acttggatct ggaaactctt 65220
ttcaaatacc agatgatatg cgaagtgcgt gtaacaaagt attagacagc gataacggaa 65280
tagactttct gagatttgtt ttgttaaaca atagatggat aatggaagat gctatatcaa 65340
aatatcagtc tccagttaat atatttaaac tagctagtga gtacggatta aacataccca 65400
aatatttaga aattgaaata gaggaagaca cattatttga cgacgagtta tactctatta 65460
tagaacgctc ttttgatgat aaatttccaa aaatatccat atcgtatatt aagttgggag 65520
aacttaggcg gcaagttgta gactttttca aattctcgtt catgtatatt gagtccatca 65580
aggtagatcg tataggagat aatattttta ttcctagcgt tataacaaaa tcaggaaaaa 65640
agatattagt aaaagatgta gaccatttaa tacgatctaa ggttagagaa catacatttg 65700
taaaagtaaa aaagaaaaac acattttcca ttttatacga ctatgatggg aacggaacag 65760
aaactagagg agaagtaata aaacgaatta tagacactat aggacgagac tattatgtta 65820
acggaaagta tttctctaag gttggtagtg caggcttaaa gcaattgact aataaattag 65880
atattaatga gtgcgcaact gtcgatgagt tagttgatga gattaataaa tccggaactg 65940
taaaacgaaa aataaaaaac caatcagcat ttgatttaag cagagaatgt ttgggatatc 66000
cagaagcaga ttttataacg ttagttaata acatgcggtt caaaatagaa aattgtaagg 66060
ttgtaaattt caatattgaa aatactaatt gtttaaataa cccgagtatt gaaactatat 66120
atggaaactt taaccagttc gtctcaatct ttaatatcgt caccgatgtc aaaaaaagat 66180
tattcgagtg aaataatatg cgcctttgat ataggtgcaa aaaatcctgc cagaactgtt 66240
ttagaagtca aggataactc cgttagggta ttggatatat caaaattaga ctggagttct 66300
gattgggaaa ggcgcatagc taaagatttg tcacaatatg aatacactac agttcttcta 66360
gaacgtcagc ctagaaggtc gccgtatgtt aaatttatct attttattaa aggcttttta 66420
tatcatacat cggctgccaa agttatttgc gtctcgcctg tcatgtctgg taattcatat 66480
agagatcgaa aaaagagatc ggtcgaagca tttcttgatt ggatggacac attcggattg 66540
cgagactccg ttccggatag acgcaaatta gacgatgtag cggatagttt caatttggct 66600
atgagatacg tattagataa atggaatact aattatacac cttataatag gtgtaaatct 66660
agaaattaca taaaaaaaat gtaataacgt tagtaacgcc attatggata atctatttac 66720
ctttctacat gaaatagaag atagatatgc cagaactatt tttaactttc atctaataag 66780
ttgcgatgaa ataggagata tatatggtct tatgaaagaa cgcatttcct cagaggatat 66840
gtttgataat atagtatata ataaagatat acatcctgcc attaagaaac tagtgtattg 66900
cgacatccaa cttactaaac acattattaa tcagaatacg tatccggtat ttaacgattc 66960
ttcacaagtg aaatgttgtc attatttcga cataaactca gataatagca atattagctc 67020
tcgtacagta gagatatttg agagggaaaa gtcatctctt gtatcatata ttaaaactac 67080
caataagaag agaaaggtca attacggcga aataaagaaa actgttcatg gaggcactaa 67140
tgcaaattac ttttccggta aaaagtctga cgagtatctg agtactacag ttagatccaa 67200
cattaatcaa ccttggatca aaaccatttc taagagaatg agagtagata tcattaatca 67260
ctctatagta acgcgtggaa aaagctctat attacaaact atagaaatta tttttactaa 67320
tagaacatgt gtgaaaatat tcaaggattc tactatgcac attattctat ccaaggacaa 67380
ggatgaaaag gggtgtatac acatgattga caaattattc tatgtctatt ataatttatt 67440
tctgttgttc gaagatatca tccaaaacga gtactttaaa gaagtagcta atgttgtaaa 67500
ccacgtactt acggctacgg cattagatga gaaattattc ctaattaaga aaatggctga 67560
acacgatgtt tatggagtta gcaatttcaa aatagggatg tttaacctga catttattaa 67620
gtcgttggat cataccgttt tcccctctct gttagatgag gatagcaaaa taaagttttt 67680
taaggggaaa aagctcaata ttgtagcatt acgatctctg gaggattgta taaattacgt 67740
gactaaatcc gagaatatga tagaaatgat gaaggaaaga tcgactattt taaatagcat 67800
agatatagaa acggaatcgg tagatcgtct aaaagaattg cttctaaaat gaaaaaaaac 67860
actgattcag aaatggatca acgactaggg tataagtttt tggtgcctga tcctaaagcc 67920
ggagtttttt atagaccgtt acatttccaa tatgtatcgt attctaattt tatattgcat 67980
cgattgcatg aaatcttgac cgtcaagcgg ccactcttat cgtttaagaa taatacagaa 68040
cgaattatga tagaaattag caatgttaaa gtgactcctc cagattactc acctataatc 68100
gcgagtatta aaggtaagag ttatgatgca ttagccacgt tcactgtaaa tatctttttt 68160
tctagacact aaataaaata tttaaaatat aatattaatg tactaaaact tatatattat 68220
taatttatct aactaaagtt agtaaattat atatataatt ttataattaa tttaatttta 68280
ctaattttat ttagtgtcta gaaaaaaa 68308
<210> 18
<211> 66390
<212> DNA
<213> 人工序列
<220>
<223> sVAC片段2
<400> 18
tttttttcta gacactaaat aaaatattta aaatataata ttaatgtact aaaacttata 60
tattattaat ttatctaact aaagttagta aattatatat ataattttat aattaattta 120
attttactaa ttttatttag tgtctagaaa aaaaattttg ggagcgtctt tatttattcg 180
aagggtaaaa atatggtaga acttggatct ggaaactctt ttcaaatacc agatgatatg 240
cgaagtgcgt gtaacaaagt attagacagc gataacggaa tagactttct gagatttgtt 300
ttgttaaaca atagatggat aatggaagat gctatatcaa aatatcagtc tccagttaat 360
atatttaaac tagctagtga gtacggatta aacataccca aatatttaga aattgaaata 420
gaggaagaca cattatttga cgacgagtta tactctatta tagaacgctc ttttgatgat 480
aaatttccaa aaatatccat atcgtatatt aagttgggag aacttaggcg gcaagttgta 540
gactttttca aattctcgtt catgtatatt gagtccatca aggtagatcg tataggagat 600
aatattttta ttcctagcgt tataacaaaa tcaggaaaaa agatattagt aaaagatgta 660
gaccatttaa tacgatctaa ggttagagaa catacatttg taaaagtaaa aaagaaaaac 720
acattttcca ttttatacga ctatgatggg aacggaacag aaactagagg agaagtaata 780
aaacgaatta tagacactat aggacgagac tattatgtta acggaaagta tttctctaag 840
gttggtagtg caggcttaaa gcaattgact aataaattag atattaatga gtgcgcaact 900
gtcgatgagt tagttgatga gattaataaa tccggaactg taaaacgaaa aataaaaaac 960
caatcagcat ttgatttaag cagagaatgt ttgggatatc cagaagcaga ttttataacg 1020
ttagttaata acatgcggtt caaaatagaa aattgtaagg ttgtaaattt caatattgaa 1080
aatactaatt gtttaaataa cccgagtatt gaaactatat atggaaactt taaccagttc 1140
gtctcaatct ttaatatcgt caccgatgtc aaaaaaagat tattcgagtg aaataatatg 1200
cgcctttgat ataggtgcaa aaaatcctgc cagaactgtt ttagaagtca aggataactc 1260
cgttagggta ttggatatat caaaattaga ctggagttct gattgggaaa ggcgcatagc 1320
taaagatttg tcacaatatg aatacactac agttcttcta gaacgtcagc ctagaaggtc 1380
gccgtatgtt aaatttatct attttattaa aggcttttta tatcatacat cggctgccaa 1440
agttatttgc gtctcgcctg tcatgtctgg taattcatat agagatcgaa aaaagagatc 1500
ggtcgaagca tttcttgatt ggatggacac attcggattg cgagactccg ttccggatag 1560
acgcaaatta gacgatgtag cggatagttt caatttggct atgagatacg tattagataa 1620
atggaatact aattatacac cttataatag gtgtaaatct agaaattaca taaaaaaaat 1680
gtaataacgt tagtaacgcc attatggata atctatttac ctttctacat gaaatagaag 1740
atagatatgc cagaactatt tttaactttc atctaataag ttgcgatgaa ataggagata 1800
tatatggtct tatgaaagaa cgcatttcct cagaggatat gtttgataat atagtatata 1860
ataaagatat acatcctgcc attaagaaac tagtgtattg cgacatccaa cttactaaac 1920
acattattaa tcagaatacg tatccggtat ttaacgattc ttcacaagtg aaatgttgtc 1980
attatttcga cataaactca gataatagca atattagctc tcgtacagta gagatatttg 2040
agagggaaaa gtcatctctt gtatcatata ttaaaactac caataagaag agaaaggtca 2100
attacggcga aataaagaaa actgttcatg gaggcactaa tgcaaattac ttttccggta 2160
aaaagtctga cgagtatctg agtactacag ttagatccaa cattaatcaa ccttggatca 2220
aaaccatttc taagagaatg agagtagata tcattaatca ctctatagta acgcgtggaa 2280
aaagctctat attacaaact atagaaatta tttttactaa tagaacatgt gtgaaaatat 2340
tcaaggattc tactatgcac attattctat ccaaggacaa ggatgaaaag gggtgtatac 2400
acatgattga caaattattc tatgtctatt ataatttatt tctgttgttc gaagatatca 2460
tccaaaacga gtactttaaa gaagtagcta atgttgtaaa ccacgtactt acggctacgg 2520
cattagatga gaaattattc ctaattaaga aaatggctga acacgatgtt tatggagtta 2580
gcaatttcaa aatagggatg tttaacctga catttattaa gtcgttggat cataccgttt 2640
tcccctctct gttagatgag gatagcaaaa taaagttttt taaggggaaa aagctcaata 2700
ttgtagcatt acgatctctg gaggattgta taaattacgt gactaaatcc gagaatatga 2760
tagaaatgat gaaggaaaga tcgactattt taaatagcat agatatagaa acggaatcgg 2820
tagatcgtct aaaagaattg cttctaaaat gaaaaaaaac actgattcag aaatggatca 2880
acgactaggg tataagtttt tggtgcctga tcctaaagcc ggagtttttt atagaccgtt 2940
acatttccaa tatgtatcgt attctaattt tatattgcat cgattgcatg aaatcttgac 3000
cgtcaagcgg ccactcttat cgtttaagaa taatacagaa cgaattatga tagaaattag 3060
caatgttaaa gtgactcctc cagattactc acctataatc gcgagtatta aaggtaagag 3120
ttatgatgca ttagccacgt tcactgtaaa tatctttaaa gaggtaatga ccaaagaggg 3180
tatatccatc actaaaataa gtagttatga gggaaaagat tctcatttga taaaaattcc 3240
gctactaata ggatacggga ataaaaatcc acttgataca gccaagtatc ttgttcctaa 3300
tgtcataggt ggagtcttta tcaataaaca atctgtcgaa aaagtaggaa ttaatctagt 3360
agaaaagatt acaacatggc caaaatttag ggttgttaag ccaaactcat tcactttctc 3420
gttttcctcc gtatcccctc ctaatgtatt accgacaaga tatcgccatt acaagatatc 3480
tctggatata tcacaattgg aagcgttgaa tatatcatcg acaaagacat ttataacggt 3540
caatattgtt ttgctgtctc aatatttatc tagagtgagt ctagaattca ttagacgtag 3600
tttatcatac gatatgcctc cagaagttgt ctatctagta aacgcgataa tagatagtgc 3660
taaacgaatt actgaatcta ttactgactt taatattgat acatacatta atgacctggt 3720
ggaagctgaa cacattaaac aaaaatctca gttaacgatc aacgagttca aatatgaaat 3780
gctgcataac tttttacctc atatgaacta tacacccgat caactaaagg gattttatat 3840
gatatcttta ctaagaaagt ttctctactg tatctaccac acttctagat atccagatag 3900
agattcgatg gtttgtcatc gcatcctaac gtacggcaaa tattttgaga cgttggcaca 3960
tgatgaatta gagaattaca taggcaacat ccgaaacgat atcatgaaca atcacaagaa 4020
cagaggcact tacgcggtaa acattcatgt actaacaact cccggactta atcacgcgtt 4080
ttctagctta ttgagtggaa agttcaaaaa gtcagacggt agttatcgaa cacatcctca 4140
ctattcatgg atgcagaata tttctattcc taggagtgtt ggattttatc cggatcaagt 4200
aaagatttca aagatgtttt ctgtcagaaa ataccatcca agtcaatatc tttacttttg 4260
ttcatcggac gttccggaaa gaggtcctca ggtaggttta gtatctcaat tgtctgtctt 4320
gagttccatt acaaatatac taacgtctga gtatttggat ttggaaaaga aaatttgtga 4380
gtatatcaga tcatattata aagatgatat aagttacttt gaaacaggat ttccaatcac 4440
tatagaaaat gctctagtcg catctcttaa tccaaatatg atatgtgatt ttgtaactga 4500
ctttagacgt agaaaacgga tgggattctt cggtaacttg gaggtaggta ttactttagt 4560
tagggatcac atgaatgaaa ttcgcattaa tattggagcg ggaagattag tcagaccatt 4620
cttggttgtg gataacggag agctcatgat ggatgtgtgt ccggagttag aaagcagatt 4680
agacgacatg acattctctg acattcagaa agagtttccg catgtcatcg aaatggtaga 4740
tatagaacaa tttactttta gtaacgtatg tgaatcggtt caaaaattta gaatgatgtc 4800
aaaggatgaa agaaagcaat acgatttatg tgactttcct gccgaattta gagatggata 4860
tgtggcatct tcattagtgg gaatcaatca caattctgga cccagagcta ttcttggatg 4920
tgctcaagct aaacaagcta tctcttgtct gagttcggat atacgaaata aaatagacaa 4980
tggaattcat ttgatgtatc cagagaggcc aatcgtgatt agtaaggctt tagaaacttc 5040
aaagattgcg gctaattgct tcggccaaca tgttactata gcattaatgt cgtacaaagg 5100
tatcaatcaa gaggatggaa ttatcatcaa aaaacaattt attcagagag gcggtctcga 5160
tatagttacc gcaaagaaac atcaagtaga aattccgttg gaaaacttta ataacaaaga 5220
aagagatagg tctaacgcct attcaaaatt agaaagtaat ggattagtta gactgaatgc 5280
tttcttggaa tccggagacg ctatggcacg aaatatctca tcaagaactc ttgaagatga 5340
ttttgctaga gataatcaga ttagcttcga tgtttccgag aaatataccg atatgtacaa 5400
atctcgcgtt gaacgagtac aagtagaact tactgacaaa gttaaggtac gagtattaac 5460
catgaaagaa agaagaccca ttctaggaga taaatttacc actagaacga gtcaaaaggg 5520
aacagtcgcg tatgtcgcgg atgaaacgga acttccatac gacgaaaatg gtatcacacc 5580
agatgtcatt attaattcta catccatctt ctctagaaaa actatatcta tgttgataga 5640
ggttatttta acagccgcat attctgctaa gccgtacaac aataagggag aaaaccgacc 5700
tgtctgtttt cctagtagta acgaaacatc catcgataca tatatgcaat tcgctaaaca 5760
atgttatgag cattcaaatc cgaaattgtc cgatgaagaa ttatcggata aaatcttttg 5820
tgaaaagatt ctctatgatc ctgaaacgga taagccttat gcatccaaag tattttttgg 5880
accaatttat tacttgcgtc tgaggcattt aactcaggac aaggcaaccg ttagatgtag 5940
aggtaaaaag acgaagctca ttagacaggc gaatgaggga cgaaaacgtg gaggaggtat 6000
caagttcgga gaaatggaga gagactgttt aatagcgcat ggcgcagcca atactattac 6060
agaagtttta aaagactcag aagaggatta tcaagatgtg tatgtttgtg aaaattgtgg 6120
agacatagca gcacaaatca agggtattaa tacatgtctt agatgttcaa aacttaatct 6180
ctctcctctc ttaacaaaaa ttgataccac gcacgtatct aaagtatttc ttactcaaat 6240
gaacgccaga ggcgtaaaag tcaaattaga tttcgaacga aggcctcctt cgttttataa 6300
accattagat aaagttgatc tcaagccgtc ttttctggtg taatattcta gtttggtagt 6360
agatacatat caatatcatc aaattcgaga tccgaattat aaaatgggcg tggattgtta 6420
actatagaat cggacgtctg atattcgaaa atctgtggag ttttaggttt tggtggaggt 6480
gtaactgcta cttgggatac tgaagtctga tattcagaaa gctgggggat gttctggttc 6540
gacatccacc gatggtgtca catcactaat cggttcggta acgtctgtgg atggaggtgc 6600
tacttctaca gaacctgtag cctcagttgt caacggagat acatttttaa tgcgaggaaa 6660
tgtataattt ggtaatggtt tctcatgtgg atctgaagaa gaggtaagat atctactaga 6720
aagataccga tcacgttcta gttctctttt gtagaactta actttttctt tctcagcatc 6780
tagttgatat tccaacctct tcacgttact acgttcagat tccaattcac gttcgcatgg 6840
gttacctccg cagtttttac gagcgatttc acgttcagcc ttcatgcgtc tctccttctc 6900
tctatcgagt ttatcagagc agtctttctg aaggcgatcg aactccataa atttctccaa 6960
cgctttgatt gtttccatag atttccgaag ttcagctttt aggactgtga ttctttttct 7020
ttcgaattca cagctggatg tgcaaccgtt tccattaccg ccatctctaa gtttcttttc 7080
tagatcggca acatttcatc cccatgcctt ttacattcct cgagtctact gtcgtcgaaa 7140
tatcgttcca gctccttttc gacatcaata actttagcac gttgtctctc aagctctctt 7200
ttgtagttat ctgattccct ggcacgttta agatcttcat gcaattgagt cagctcttaa 7260
cacaatctct tgcttcttcg tcatagtact tacaatcact atgggatcca ttgttaccac 7320
gtctacactc ggcgagctcg cgtttaagag attcaatttc ccgtttgtat tggtccatgt 7380
ttccattgct accaccatta gatttacagg ctgctagttg tcgttcgaga tcagaaatac 7440
gggttttctt ggaattgatt tcgtcgatgt acttggcatc gaaacactta ttaagttctt 7500
tttccaattc tacgatttta tttctttcgc gagtcaattc cctcctgtag taactatctg 7560
ttttgtcaga ttcacgctct ctacgtagac tttcttgcaa gttactaatt tgttccctag 7620
cacgtccgag tttagtttta tatgctgaat agagttctga ttcatccttt gagcagatct 7680
ctagcgatcg tttaagattc ctgattctag tctttagcct atttacctcc tcagaagatg 7740
ttccgttacc gttgcgttta cactcgttaa gctgtctatc aagatccatg attctatctc 7800
taagacgttg catctctctt tccatatcag cattgctttc attattacgt ctgcagtcac 7860
tcaactgtct ttcaatatct gagattctat ctctaagacg tcgcatctct ctctgtttcg 7920
gcattggttt cattattacg tctacagtcg ttcaactgtc tttcaagatc tgatattcta 7980
gattggagtc tgctaatctc tgtagcattt tcacggcatt cactcagttg tctttcaaga 8040
tctgagattt tagattggag tctgctaatc tctgtaagat ttcctcctcc gctctcgatg 8100
cagtcggtca acttattctc tagttctcta atacgcgaac gcagtgcatc aacttcttgc 8160
gtgtcttcct ggttgcgtgt acattcatcg agtctagatt cgagatctct aacgcgtcgt 8220
cgttcttcct caagttctct gcgtactaca gaaagcgtgt ccctatcttg ttgatattta 8280
gcaatttctg attctagagt actgattttg cttacgtagt tactaatagt tgtcttggcc 8340
ttatcaagat cctccttgta tttgtcgcat tccttgatat ccctacgaag tctggacagt 8400
tcccattcga cattacgacg tttatcgatt tcagctcgga gatcgtcatc gcgttgtttt 8460
agccacatac gactgagttc aagttctcgt tgacaagatc catctacttt tccattccta 8520
atagtatcca gttccttttc tagttctgaa cgcatttctc gttccctatc aagcgattct 8580
ctcaattctc ggatagtctt cttatcaatt tctaataaat ctgaaccatc atctgtccca 8640
ttttgaatat ccctgtgttc tttgatctct tttgtaagtc ggtcgattct ttcggtttta 8700
taaacagaat ccctttccaa agtcctaatc ttactgagtt tatcactaag ttctgcattc 8760
aattcggtga gttttctctt ggcttcttcc aactctgttt taaactctcc actatttccg 8820
cattcttcct cgcatttatc taaccattca attagtttat taataactag ttggtaatca 8880
gcgattccta tagccgttct tgtaattgtg ggaacataat taggatcttc taatggattg 8940
tatggcttga tagcatcatc tttatcatta ttagggggat ggacaacctt aattggttgg 9000
tcctcatctc ctccagtagc gtgtggttct tcaataccag tgttagtaat aggcttaggc 9060
aaatgcttgt cgtacgcggg cacttcctca tccatcaagt atttataatc gggttctacg 9120
tctgaatatt cttttctaag agacgcgact tcgggagtta gtagaagaac tctgtttctg 9180
tatctatcaa cgctggaatc aatactcaag ttaaggatag cgaatacctc atcgtcatca 9240
tccgtatctt ctgaaacacc atcatatgac atttcatgaa gtctaacgta ttgataaata 9300
gaatcagatt tagtattaaa cagatcctta acctttttag taaacgcata tgtatatttt 9360
agatctccag atttcataat atgatcacat gccttaaatg tcagtgcttc catgatataa 9420
tctggaacac taatgggtga cgaaaaagat acagcaccat atgctacgtt gataaataaa 9480
tctgaaccac taagtagata atgattaatg ttaaggaaga ggaaatattc agtatataga 9540
tatgccttag catcatatct tgtactaaac acgctaaaca gtttattgat gtgatcaatt 9600
tccaacagaa taattagagc agcgggaata ccaacaaaca tattaccaca tccgtatttt 9660
ctatgaatat cacatatcat gttaaaaaat cttgatagaa gagcgaatat ctcgtctgac 9720
ttaatgagtc gtagttcagc agcaacataa gtcataactg taaatagaac atactttcct 9780
gtagtgttga ttctagactc cacatcaaca ccattattaa aaatagtttt atatacatct 9840
ttaatctgct ctccgttaat cgtcgaacgt tctagtatac ggaaacactt tgatttctta 9900
tctgtagtta atgacttagt gatatcacga agaatattac gaattacatt tcttgttttt 9960
cttgagagac ctgattcaga actcaactca tcgttccata gtttttttac ctcagtggcg 10020
aaatctttgg agtgcttggt acatttttca ataaggttcg tgacctccat ttattataaa 10080
aaattttatt caaaacttaa ctacaatcgg gtaattataa aatcgtagat ctcccatgtg 10140
gtggaatact accatctatc gcatgtggat ggacagtagg taatggccat gggaacagta 10200
atgtttgcat atttatcttt cttgccagta ttactgcata ttgtcccaat gtttcgatgt 10260
gatgttctaa cctatcaact gccgctgtat cacaacaata gtgtccgatg aaattaagat 10320
tatgatccaa tgtgtttaat atatgattat caagtcttat acgatccgcg tcttttttga 10380
caggatcagg ttcttctaca ggaagaagtt tcggcctctt atgatattca tgtctgggaa 10440
acggtggtct agggtgaggc tccggtatcg gagtgggttt tggattataa tcatcatcgt 10500
ctatgacatc atcttcgact tcgatattta ttttgctatc ttgatgatgt cctgtatcag 10560
ttgcattttc agcactcgac tgaatattag cgcattcatt gtctattatt accatatttc 10620
taaacccaaa atgtatgtgt tgaacatcag tactatcgtt gatgagtctt atagcatgaa 10680
ttcgcttatc gttatcgggt ttatcttctg tcaccttagc aattcctttt ttattaaact 10740
ctacataatc atatccattt ctattgtttg ttctaatata aacgagtata gcatcattgc 10800
taaatttttc aatagtatcg aaaacagaat atcctaaacc atataatata tattcaggga 10860
cactcaaact aaatgtccag gattctccta aatacgtaaa ctttaatagt gcgaaatcat 10920
tcaaaaatct accacttata gatagatagt acataaatgc gtatagtagt ctacctatct 10980
ctttattatg aaaaccggca ttacgatcat atatgtcgtg atatacctgt gatccgttta 11040
cgttaaacca taaatacatg ggtgatccta taaacatgaa tttatttcta attctcagag 11100
ctatagttaa ttgaccgtgt aatatttgct tacatgcata cttgatacgc tcattaataa 11160
aatttttatc attgctcgtt atctcagaat cgtatatata aggagtacca tcgtgattct 11220
taccagatat tatacaaaat actatatata aaatatattg accaacgtta gtaatcatat 11280
aaatgtttaa cgttttaaat tttgtattca atgatccatt atcatacgct agcatggtct 11340
tatgatattc attctttaaa atataatatt gtgttagcca ttgcattggg gctcctaatg 11400
gagatttttt attctcatcc attttaggat aggctttcat aaagtcccta ataacttcgt 11460
gaataatgtt tctatgtttt ctactgatgc atgtatttgc ttcgattttt ttatcccatg 11520
tttcatctat catagattta aacgcagtaa tgctcgcaac attaacatct tgaaccgttg 11580
gtacaattcc gttccataaa tttataatgt tcgccattta tataactcat tttttgaata 11640
tacttttaat taacaaaaga gttaagttac tcatatgggc gccgtccagt ctgaacatca 11700
atctttttag ccagagatat catagccgct cttagagttt cagcgtgatt ttccaaccta 11760
aatagaactt catcgttgcg tttacaacac ttttctattt gttcaaactt tgttgttaca 11820
ttagtaatct ttttttccaa attagttagc cgttgtttga gagtttcctc attgtcgtct 11880
tcatcggctt taacaattgc ttcgcgttta gcctctggct ttttagcagc ctttgtagaa 11940
aaaaattcag ttgctggaat tgcaagatcg tcatctccgg ggaaaagagt tccgtccatt 12000
taaagtacag attttagaaa ctgacactct gcgttattta tatttggtac aacacatgga 12060
ttataaatat cgatgttaat aacatcagaa aatgtaaagt ctatacattg ttgcatcgtg 12120
ttaaattttc taatggatct agtattattg ggtccaactt ctgcctgaaa tccaaatatg 12180
gaagcggata caaaaccgtt tcctggataa accacacatc tccacttttg ctttacatca 12240
gaaattgtgt cgttgacatc ttgaactctc ctatctaatg ccggtgttcc acctatagat 12300
tttgaatatt cgaatgctgc atgagtagca ttaaattcct taatattgcc ataattttca 12360
tatattgagt aaccctggat aaaaagtaaa cacaccgcag ccgtcgctac cacaataaaa 12420
aaaattgata gagagttcat ttataatcta ttagaagctg acaaaatttt tttacacgca 12480
tcagacaatg ctttaataaa tagttcaaca tctacttttg tcatatcgaa ccgatggtat 12540
gattctaacc tagaattaca tccgaaaaag ttgactatgt tcatagtcat taagtcatta 12600
acaaacaaca ttccagactc tggattataa gacgatactg tttcgtcaca attacctacc 12660
ttaatcatgt gattatgaat attggctatt agagcacctt ctaagaaatc tataatatct 12720
ttgaaacacg atttaaaatc aaaccacgaa tatacttcta cgaagaaagt tagtttaccc 12780
ataggagaaa taactataaa tggagatcta aatacaaaat ccggatctat gatagtttta 12840
acattattat attctctatt aaatacctcc acatctaaaa atgttaattt tgaaactatg 12900
tcttcgttta ttaccgtacc tgaactaaac gctataagct ctattgtttg agaactcttt 12960
aaacgatatt cttgaaatac atgtaacaaa gtttccttta actcggtcgg tttatctacc 13020
atagttacag aatttgtatc cttatctata atataataat caaaatcgta taaagttata 13080
taattatcgc gttcagattg ggatcttttc aaatagacta aaaaccccat ttctctagta 13140
agtatcttat gtatatgttt gtaaaatatc ttcatggtgg gaatatgctc taccgcagtt 13200
agccattcct cattgacagc ggtagatgta ttagacaaaa ctattccaat gtttaacaag 13260
ggccatttta cgagattatt aaatccttgt ttgataaatg tagccaatga gggttcgagt 13320
tcaacgacga ttgaattctc ttcccgcgga tgctgcatga tgaacgacgg gatgttgttc 13380
gattgatttg gaattctttt tcgacttttt gtttatatta aatattttaa aatttatagc 13440
ggatagcaat tcatgtacca cggataatgt agacgcgtat tgcgcatcga tatctttatt 13500
attagataaa tttatcaata aatgtgagaa gtttgcctcg ttaaggtctt ccatttaaat 13560
attatataaa catttgtgtt tgtatcttat tcgtctttta tggaatagtt ttttactagt 13620
aaagctgcaa ttacacactt tgtccgtaaa acataaatat aaacaccagc ttttatcaat 13680
cgttccaaaa agtcgacggc ggacattttt aacatggcat ctattttaaa tacacttagg 13740
tttttggaaa aaacatcatt ttataattgt aacgattcaa taactaaaga aaagattaag 13800
attaaacata agggaatgtc atttgtattt tataagccaa agcattctac cgttgttaaa 13860
tacttgtctg gaggaggtat atatcatgat gatttggttg tattggggaa ggtaacaatt 13920
aataatctaa agatgatgct attttacatg gatttatcat atcatggagt gacaagtagt 13980
ggagcaattt acaaattggg atcgtctatc gatagacttt ctctaaatag gactattgtt 14040
acaaaagtta ataattatga tgatacattt tttgacgacg atgattgatc gctattgcac 14100
aattttgttt ttttactttc taatatagcg tttagattct ttttcatgtg cgaatattga 14160
tttactaaaa tatcgatgtt taacttttgt tctatgacgt ccttatcagc ggtatcggta 14220
catatacgta attcaccttc acaaaatacg gagtcttcga taataatagc caatcgatta 14280
ttggatctag ctgtctgtat catattcaac atgtttaata tatcctttcg tttccccttt 14340
acaggcatcg atcgtagcat attttccgcg tctgagatgg aaatgttaaa actacaaaaa 14400
tgcgtaatgt tagcccgtcc taatattggt acgtgtctat aagtttggca tagtagaata 14460
atagacgtgt ttaaatgcct tccaaagttt aagaattcta ttagagtatt gcattttgat 14520
agtttatcac ctacatcatc aaaaataagt aaaaagtgtg ctgatttttt atgattttgt 14580
gcgacagcaa tacatttttc tatgttactt ttagttcgta tcagattata ttctagagat 14640
tcctgactac taacgaaatt aatatgattt ggccaaatgt atccatcata atctgggtta 14700
taaacgggtg taaacaagaa tatatgttta tattttttaa ctagtgtaga aaacagagat 14760
agtaaataga tagtttttcc agatccagat cctcccgtta aaaccattct aaacggcatt 14820
tttaataaat tttctcttga aaattgtttt tcttggaaac aattcataat tatatttaca 14880
gttactaaat taatttgata ataaatcaaa atatggaaaa ctaaggtcgt tagtagggag 14940
gagaacaaag aaggcacatc gtgacataaa taacatttat tatcatgatg acaccagaaa 15000
acgacgaaga gcagacatct gtgttctccg ctactgttta cggagacaaa attcaaggaa 15060
agaataaacg caaacgcgtg attggtctat gtattagaat atctatggtt atttcactac 15120
tatctatgat taccatgtcc gcgtttctca tagtgcgcct aaatcaatgc atgtctgcta 15180
acgaggctgc tattactgac gccgctgttg ccgttgctgc tgcatcatct actcatagaa 15240
aggttgcgtc tagcactaca caatatgatc acaaagaaag ctgtaatggt ttatattacc 15300
agggttcttg ttatatatta cattcagact accagttatt ctcggatgct aaagcaaatt 15360
gcactgcgga atcatcaaca ctacccaata aatccgatgt cttgattacc tggctcattg 15420
attatgttga ggatacatgg ggatctgatg gtaatccaat tacaaaaact acatccgatt 15480
atcaagattc tgatgtatca caagaagtta gaaagtattt ttgtgttaaa acaatgaact 15540
aatatttatt tttgtacatt aataaatgaa atcgcttaat agacaaactg taagtaggtt 15600
taagaagttg tcggtgccgg ccgctataat gatgatactc tcaaccatta ttagtggcat 15660
aggaacattt ctgcattaca aagaagaact gatgcctagt gcttgcgcca atggatggat 15720
acaatacgat aaacattgtt atttagatac taacattaaa atgtctacag ataatgcggt 15780
ttatcagtgt cgtaaattac gagccagatt gcctagaccg gatactagac atctgagagt 15840
attgtttagt attttttata aagattattg ggtaagttta aaaaagacca atgataaatg 15900
gttagatatt aataatgata aagatataga tattagtaaa ttaacaaatt ttaaacaact 15960
aaacagtacg acggatgctg aagcgtgtta tatatacaag tctggaaaac tggttaaaac 16020
agtatgtaaa agtactcaat ctgtactatg tgttaaaaaa ttctacaagt gacaacaaaa 16080
aatgaattaa taataagtcg ttaacgtacg ccgccatgga cgccgcgttt gttattactc 16140
caatgggtgt gttgactata acagatacat tgtatgatga tctcgatatc tcaatcatgg 16200
actttatagg accatacatt ataggtaaca taaaaactgt ccaaatagat gtacgggata 16260
taaaatattc cgacatgcaa aaatgctact ttagctataa gggtaaaata gttcctcagg 16320
attctaatga tttggctaga ttcaacattt atagcatttg tgccgcatac agatcaaaaa 16380
ataccatcat catagcatgc gactatgata tcatgttaga tatagaagat aaacatcagc 16440
cattttatct attcccatct attgatgttt ttaacgctac aatcatagaa gcgtataacc 16500
tgtatacagc tggagattat catctaatca tcaatccttc agataatctg aaaatgaaat 16560
tgttgtttaa ttcttcattc tgcatatcag acggcaatgg atggatcata attgatggga 16620
aatgcaatag taatttttta tcataaaagt tgtaaagtaa ataataaaac aataaatatt 16680
gaactagtag tacgtatatt gagcaatcag aaatgatgct ggtacctctt atcacggtga 16740
ccgtagttgc gggaacaata ttagtatgtt atatattata tatttgtagg aaaaagatac 16800
gtactgtcta taatgacaat aaaattatca tgacaaaatt aaaaaagata aagagttcta 16860
attccagcaa atctagtaaa tcaactgata gcgaatcaga ctgggaggat cactgtagtg 16920
ctatggaaca aaacaatgac gtagataata tttctaggaa tgagatattg gacgatgata 16980
gcttcgctgg tagtttaata tgggataacg aatccaatgt catggcgcct agcacagaac 17040
acatttacga tagtgttgct ggaagcacgc tgctaataaa taatgatcgt aatgaacaga 17100
ctatttatca gaacactaca gtagtaatta atgagacgga gactgttgaa gtacttaatg 17160
aagataccaa acagaatcct aactattcat ccaatccttt cgtaaattat aataaaacca 17220
gtatttgtag caagtcaaat ccgttcatta cagaactcaa caataaattt agtgagaata 17280
atccgtttag acgagcacat agcgatgatt atcttaataa gcaagaacaa gatcatgaac 17340
acgatgatat agaatcatcg gtcgtatcat tggtgtgatt agtttccttt ttataaaatt 17400
gaagtaatat ttagtattat tgctgccgtc acgttgtaca aatggagata ttccctgtat 17460
tcggcatttc taaaattagc aattttattg ctaataatga ctgtagatat tatatagata 17520
cagaacatca aaaaattata tctgatgaga tcaatagaca gatggatgaa acggtacttc 17580
ttaccaacat cttaagcgta gaagttgtaa atgacaatga gatgtaccat cttattcccc 17640
atagactatc gactattata ctctgtatta gttctgtcgg aggatgtgtt atctctatag 17700
ataatgacat caatgacaaa aatattctaa catttcccat tgatcatgct gtaatcatat 17760
ccccactgag taaatgtgtc gtagttagca agggtcctac aaccatattg gttgttaaag 17820
cggatatacc cagcaaacga ttggtaacat cgtttacaaa cgacatactg tatgtaaaca 17880
atctgtcact gattaattat ttgccgttgt ctgtattcat tattagacga gtcaccgact 17940
atttggatag acacatatgc gatcagatat ttgcgaataa taagtggtat tccattataa 18000
ccatcgacga taagcaatat cctattccat caaactgtat aggtatgtcc tctgccaagt 18060
acataaattc tagcatcgag caagatactt taatacatgt ttgtaacctc gagcatccat 18120
tcgacttagt atacaaaaaa atgcagtcgt acaattctgt acctatcaag gaacaaatat 18180
tgtacggtag aattgataat ataaatatga gcattagtat ttctgtggat taatagattt 18240
ctagtatggg gatcattaat catctctaat ctctaaatac ctcataaaac gaaaaaaaag 18300
ctattatcaa atactgtacg gaatggattc attctcttct ctttttatga aactctgttg 18360
tatatctact gataaaactg gaagcaaaaa atctgataaa aagaataaga ataagatcaa 18420
ggattatatg gaacacgatt attataaaat aacaatagtt cctggttcct cttccacgtc 18480
tactagctcg tggtattata cacatgccta gtaatagtct ctttgcgttg acggaaagca 18540
gactagaaat aacaggctaa aatgttcaga caccataata gttcccaacc cagataataa 18600
cagagtacca tcaacacatt cctttaaact caatcccaaa cccaaaaccg ttaaaatgta 18660
tccggccaat tgatagtaga taatgaggtg tacagcgcat gataatttac acagtaacca 18720
aaatgaaaat actttagtaa ttataagaaa tatagatggt aacgtcatca tcaacaatcc 18780
aataatatgc cggagagtaa acattgacgg ataaaacaaa aatgctccgc ataactctat 18840
catggcaata acacaaccaa atacttgtaa gattcctaaa ttagtagaaa atacaacgga 18900
tatcgatgta taagtgatct cgagaaataa taagaataaa gtaatgcccg taaagataaa 18960
catcaacatt gtttggtaat cattaaacca attagtatga agttgaacta atttcacagt 19020
agattttatt ccagtgttat cctcgcatgt atacgtacct ggtaagatat ctttatattc 19080
tataatcaat gagacatcac tatccgataa cgaatgaagt ctagcactag tatgccattt 19140
acttaatatg gtcgtcttgg aagttttatt ataagttaaa atatcatggt tgtccaattt 19200
ccatctaata tactttgtcg gattatctat agtacacgga ataatgatgg tattattaca 19260
tgctgtatac tctatagtct ttgtagatgt tataatcata aaagtacaga ggtatatcaa 19320
cgatattcta actcttgaca ttttttattt atttaaaatg atacctttgt tatttatttt 19380
attctatttt gctaacggta tcgaatggca taagtttgaa acgagtgaag aaataatttc 19440
tacttactta ttagacgacg tattatacac gggtgttaat ggggcggtat acacattttc 19500
aaataataaa ctaaacaaaa ctggtttagc taatactaat tatatcacaa catctataaa 19560
agtagaggat gcggataagg atacattagt atgcggaacc aataacggaa atcccaaatg 19620
ttggaaaata gacggttcag acgacccaaa acatagaggt agaggatacg ctccttatca 19680
aaatagcaaa gtaacgataa tcagtcacaa cggatgtgta ctatctgaca taaacatatc 19740
aaaagaagga attaaacgat ggagaagatt tgacggacca tgtggttatg atttatacac 19800
ggcggataac gtaattccaa aagatggttt acgaggagca ttcgtcgata aagatggtac 19860
ttatgacaaa gtttacattc ttttcactga tactatcggc tcaaagagaa ttgtcaaaat 19920
tccgtatata gcacaaatgt gcctaaacga cgaaggtggt ccatcatcat tgtctagtca 19980
tagatggtcg acgtttctca aagtcgaatt agaatgtgat atcgacggaa gaagttatag 20040
acaaattatt cattctagaa ctataaaaac agataatgat acgatactat atgtattctt 20100
cgatagtccg cattatgtac ctattctatg aataccatta aacaatcttt ttctacgtca 20160
aaattggaag gatatacaaa gcaattgccg tctccagctc ctggtatatg tctaccagct 20220
ggaaaagttg ttccacatac cacgtttgaa gtcatagaaa aatataatgt actagatgat 20280
attataaagc ctttatctaa ccaacctatc ttcgaaggac cgtctggtgt taaatggttc 20340
gatataaagg agaaggaaaa tgaacatcgg gaatatagaa tatacttcat aaaagaaaat 20400
tctatatatt cgttcgatac aaaatctaaa caaactcgta gctcgcaagt cgatgcgcga 20460
ctattttcag taatggtaac ttcgaaaccg ttatttatag cagatatagg gataggagta 20520
ggaatgccac aaatgaaaaa aatacttaaa atgtaatctt aatcgagtac accacacgac 20580
aatgaacaaa cataagacag attatgctgg ttatgcttgc tgcgtaatat gcggtctaat 20640
tgttggaatt atttttacag cgacactatt aaaagttgta gaacgtaaat tagttcatac 20700
accatcaata gataaaacga taaaagatgc atatattaga gaagattgtc ctactgactg 20760
gataagctat aataataaat gtatccattt atctactgat cgaaaaacct gggaggaagg 20820
acgtaatgca tgcaaagctc taaatccaaa ttcggatcta attaagatag agactccaaa 20880
cgagttaagt tttttaagaa gcattagacg cggatattgg gtaggagaat ccgaaatatt 20940
aaaccagaca accccatata attttatagc taagaatgcc acgaagaatg gaactaaaaa 21000
acggaaatat atttgtagca caacgaatac tcccaaactg cattcgtgtt acactatata 21060
acaattacac tacattttta tcataccact acttcggtta gatgttttag aaaaaaataa 21120
atatcgccgt accgttcttg tttttataaa aataacaatt aacaattatc aaattttttc 21180
tttaatattt tacgtggttg accattcttg gtggtaaaat aatctcttag tgttggaatg 21240
gaatgctgtt taatgtttcc acactcatcg tatattttga cgtatgtagt cacatcgttt 21300
acgcaatagt cagactgtag ttctatcatg cttcctacat tagaaggagg aacagtttta 21360
aagtctcttg gttttaatct attaccgtta gttttcatga aatcctttgt tttatccact 21420
tcacatttta aataaatgtc cactatacat tcttctgtta attttactag atcgtcatgg 21480
gtcatagaat ttataggttc cgtagtccat ggatccaaac tagcaaactt cgcgtatacg 21540
gtatcgcgat tagtgtatac accaactgta tgaaaattaa gaaaacagtt taatagatca 21600
acagaaatat ttaatcctcc gtttgataca gatgcaccat atttatggat tttggattca 21660
cacgttgttt gtctgagggg ttcgtctagc gttgcttcta cataaacttc tattcccata 21720
tattctttat tgtcagaatc gcataccgat ttatcatcat acactgtttg aaaactaaat 21780
ggtatacaca tcaaaataac aaatactaac gagtacattc tgcaatattg ttatcgtaat 21840
tggaaaaata gtgttcgagt gagttggatt atgtgagtat tggattgtat attttatttt 21900
atattttgta ataagaataa aatgctaatg tcaagtttat tccaatagat gtcttattaa 21960
aaacatatat aataaataac aatggctgaa tggcataaaa ttatcgagga tatctcaaaa 22020
aataataagt tcgaggatgc cgccatcgtt gattacaaga ctacaaagaa tgttctagct 22080
gctattccta acagaacatt tgccaagatt aatccgggtg aaattattcc tctcatcact 22140
aatcgtaata ttctaaaacc tcttattggt cagaaatatt gtattgtata tactaactct 22200
ctaatggatg agaacacgta tgctatggag ttgcttactg ggtacgcccc tgtatctccg 22260
atcgttatag cgagaactca taccgcactt atatttttga tgggtaagcc aacaacatcc 22320
agacgtgacg tgtatagaac gtgtagagat cacgctaccc gtgtacgcgc aactggtaat 22380
taaaataaaa agtaatattc atatgtagtg tcaattttaa atgatgatga tgaaatggat 22440
aatatccata ttgacgatgt caataatgcc ggtattggca tacagctcat cgatttttag 22500
atttcattca gaggatgtgg aattatgtta tgggcatttg tattttgata ggatctataa 22560
tgtagtaaat ataaaatata atccgcatat tccatataga tataatttta ttaatcgcac 22620
gttaaccgta gatgaactag acgataatgt cttttttaca catggttatt ttttaaaaca 22680
caaatatggt tcacttaatc ctagtttgat tgtctcatta tcaggaaact taaaatataa 22740
tgatatacaa tgctcagtaa atgtatcgtg tctcattaaa aatttggcaa cgagtacatc 22800
tactatatta acatctaaac ataagactta ttctctacat cggtccacgt gtattactat 22860
aataggatac gattctatta tatggtataa agatataaat gacaagtata atggcatcta 22920
tgattttact gcaatatgta tgctaatagc gtctacattg atagtgacca tatacgtgtt 22980
taaaaaaata aaaatgaact cttaattatg ctatgctatt agaaatggat aaaatcaaaa 23040
ttacggttga ttcaaaaatt ggtaatgttg ttaccatatc gtataacttg gaaaagataa 23100
ctattgatgt cacacctaaa aagaaaaaag aaaaggatgt attattagcg caatcagttg 23160
ctgtcgaaga ggcaaaagat gtcaaggtag aagaaaaaaa tattatcgat attgaagatg 23220
acgatgatat ggatgtagaa agcgcataat acgatctata aaaataagta tataaatact 23280
ttttatttac tgtactctta ctgtgtagtg gtgataccct actcgattat ttttttaaaa 23340
aaatacttat tctgattctt ctagccattt ccgtgttcgt tcgaatgcca catcgacgtt 23400
aaagataggg gagtagttga aatctagttc tgcattgttg gtacgcacct caaatgtagt 23460
gttggatatc ttcaacgtat agttgttgag tagtgatggt tttctaaata gaattctctt 23520
catatcattc ttgcacgcgt acatttttag catccatctt ggaattctag atccttgttc 23580
tattcccaat ggtttcatca atagaagatt aaacatatcg tacgaacacg atggagagta 23640
atcgtagcaa aagtaagcat ttcctttaat ctcagatccc ggatactgga tatattttgc 23700
agccaacacg tgcatccatg caacatttcc tacatatacc cggctatgca ccgcgtcatc 23760
atcgactgta cgatacataa tgttaccgtg ttgcttacat tgctcgtaaa agactttcgt 23820
caatttgtct ccttctccgt aaattccagt gggtcttagg caacaagtat acaattttgc 23880
tccattcatg attacggaat tattggcttt cataaccagt tgctcggcca tacgtttact 23940
ttttgcgtat acatgtcctg gtgatatatc ataaagggta tgctcatggc cgatgaatgg 24000
atcaccgtgt ttatttggtc ctattgcttc catgctacta gtatagatca aatacttgat 24060
tcctaggtcc acacaagctg ccaatatagt ctgtgttcca taatagttta ctttcatgat 24120
ttcattatcg gtgtattttc caaatacatc cactagagca gccgtatgaa taatcagatt 24180
taccccatct agcgcttctc tcaccttatc aaagtcgttt atatcacatt gtatatagtt 24240
tataacctta actttcgagg ttattggttg tggatcttct acaatatcta tgactctgat 24300
ttcttgaaca tcatctgcac taattaacag ttttactata tacctgccta gaaatccggc 24360
accaccagta accgcgtaca cggccattgc tgccactcat aatatcagac tacttattct 24420
attttactaa ataatggctg tttgtataat agaccacgat aatatcagag gagttattta 24480
ctttgaacca gtccatggaa aagataaagt tttaggatca gttattggat taaaatccgg 24540
aacgtatagt ttgataattc atcgttacgg agatattagt caaggatgtg attccatagg 24600
cagtccagaa atatttatcg gtaacatctt tgtaaacaga tatggtgtag catatgttta 24660
tttagataca gatgtaaata tatctacaat tattggaaag gcgttatcta tttcaaaaaa 24720
tgatcagaga ttagcgtgtg gagttattgg tatttcttac ataaatgaaa agataataca 24780
ttttcttaca attaacgaga atggcgtttg atatatcagt taatgcgtct aaaacaataa 24840
atgcattagt ttacttttct actcagcaaa ataaattagt catacgtaat gaagttaatg 24900
atacacacta cactgtcgaa tttgataggg acaaagtagt tgacacgttt atttcatata 24960
atagacataa tgacaccata gagataagag gggtgcttcc agaggaaact aatattggtt 25020
gcgcggttaa tacgccggtt agtatgactt acttgtataa taagtatagt tttaaactga 25080
ttttagcaga atatataaga cacagaaata ctatatccgg caatatttat tcggcattga 25140
tgacactaga tgatttggct attaaacagt atggagacat tgatctatta tttaatgaga 25200
aacttaaagt agactccgat tcgggactat ttgactttgt caactttgta aaggatatga 25260
tatgttgtga ttctagaata gtagtagctc tatctagtct agtatctaaa cattgggaat 25320
tgacaaataa aaagtatagg tgtatggcat tagccgaaca tatatctgat agtattccaa 25380
tatctgagct atctagacta cgatacaatc tatgtaagta tctacgcgga cacactgaga 25440
gcatagagga taaatttgat tattttgaag acgatgattc gtctacatgt tctgccgtaa 25500
ccgacaggga aacggatgta taattttttt tatagcgtga aggatatgat aaaaaatata 25560
attgttgtat ttatcccatt ccaatcacct tatatgattc tgtaacacaa tgaaggagtc 25620
tcatagatgt atagaggtca gatactggtt tgataaactg tttattccac atgagtatgt 25680
ttgactttat ggttagaccc gcatacttta acaaatcact gaaaattgga gttaggtatt 25740
gacctctcag aatcagttgc cgttctggaa cattaaatgt attttttatg atatactcca 25800
acgcatttat gtgggcatac aacaagtcat tactaatgga gtattccaag agttttagtt 25860
gtctagtatt taacaagaga agagatttca acagactgtt tatgaactcg aatgccgcct 25920
cattgtcgct tatattgatg atgtcgaatt ctcccaatat catcaccgat gagtagctca 25980
tcttgttatc gggatccaag ttttctaaag atgtcattaa accctcgatc atgaatggat 26040
ttatcatcat cgtttttatg ttggacatga gcttagtccg tttgtccaca tctatagacg 26100
acgatttctg aattatttta tatatccctc tctttaactc caggaacttg tcaggatggt 26160
ctactttaat atgttctcgt ctaagagatg aaaatctttg gatggttgca cgcgactttt 26220
ctctaaagga tgacgttgcc caagatcctc tcttaaatga atccatctta tccttggaca 26280
agatggacag tctattttcc ttagatggtt taatattttt gttacccatg atctataaag 26340
gtagacctaa tcgtctcgga tgacctatat atttattttc agttttatta tacgcataaa 26400
ttgtaaaaaa tatgttaggt ttacaaaaat gtctcgtggg gcattaatcg tttttgaagg 26460
attggacaaa tctggaaaaa caacacaatg tatgaacatc atggaatcta taccggcaaa 26520
cacgataaaa tatcttaact ttcctcagag atccactgtc actggaaaga tgatagatga 26580
ctatctaact cgtaaaaaaa cctataatga tcatatagtt aatctattat tttgtgcaaa 26640
tagatgggag tttgcatctt ttatacaaga acaactagaa cagggaatta ctttaatagt 26700
tgatagatac gcgttctctg gagtagcgta tgccgccgct aaaggcgcgt caatgactct 26760
cagtaagagt tatgaatctg gattgcctaa acccgactta gttatattct tggaatctgg 26820
tagcaaagaa attaatagaa acgtcggcga ggaaatttat gaagatgtta cattccaaca 26880
aaaggtatta caagaatata aaaaaatgat tgaagaagga gatattcatt ggcaaattat 26940
ttcttctgaa ttcgaggaag atgtaaagaa ggagttgatt aagaatatag ttatagaggc 27000
tatacacacg gttactggac cagtggggca actgtggatg taatagtgaa attacatttt 27060
ttataaatag atgttagtac agtgttataa atggatgaag catattactc tggcaacttg 27120
gaatcagtac tcggatacgt gtccgatatg cataccgaac tcgcatcaat atctcaatta 27180
gttattgcca agatagaaac tatagataat gatatattaa acaaggacat tgtaaatttt 27240
atcatgtgta gatcaaactt ggataatcca tttatctctt tcctagatac tgtatatact 27300
attatagatc aagagaacta tcagaccgaa ttgattaatt cattagacga caatgaaatt 27360
atcgattgta tagttaataa gtttatgagc ttttataagg ataacctaga aaatatagta 27420
gatgctatca ttactctaaa atatataatg aataatccag attttaaaac tacgtatgcc 27480
gaagtactcg gttccagaat agccgatata gatattaaac aagtgatacg tgagaatata 27540
ctacaattgt ctaatgatat ccgcgaacga tatttgtgaa aaatattaaa aaaaaatact 27600
ttttttatta aatgacgtcg cttcgcgaat ttagaaaatt atgctgtgat atatatcacg 27660
catcaggata taaagaaaaa tctaaattaa ttagagactt tataacagat agggatgata 27720
aatatttgat cattaagcta ttgcttcccg gattagacga tagaatttat aacatgaacg 27780
ataaacaaat tataaaatta tatagtataa tatttaaaca atctcaggaa gatatgctac 27840
aagatttagg atacggatat ataggagaca ctattaggac tttcttcaaa gagaacacag 27900
aaatccgtcc acgagataaa agcattttaa ctttagaaga cgtggatagt ttcttaacta 27960
cgttatcatc cgtaactaaa gaatcgcatc aaataaaatt attgactgat atcgcatccg 28020
tttgtacatg taatgattta aaatgtgtag tcatgcttat tgataaagat ctaaaaatta 28080
aagcgggtcc tcggtacgta cttaacgcta ttagtcctaa tgcctatgat gtgtttagaa 28140
aatctaataa cttgaaagag ataatagaaa atgcatctaa acaaaatcta gactctatat 28200
ctatttctgt tatgactcca attaatccca tgttagcgga atcgtgtgat tctgtcaata 28260
aggcgtttaa aaaatttcca tcaggaatgt ttgcggaagt caaatacgat ggtgaaagag 28320
tacaagttca taaaaataat aacgagtttg ccttctttag tagaaacatg aaaccagtac 28380
tctctcataa agtggattat ctcaaagaat acataccgaa agcatttaaa aaagctacgt 28440
ctatcgtatt ggattctgaa attgttcttg tagacgaaca taatgtaccg ctcccgtttg 28500
gaagtttagg aatacacaaa aagaaagaat ataaaaactc taacatgtgt ttgttcgtgt 28560
ttgactgttt gtactttgat ggattcgata tgacggacat tccattgtac gaacgaagat 28620
cttttctcaa agatgttatg gttgaaatac ccaatagaat agtattctca gagttgacga 28680
atattagtaa cgagtctcag ttaactgacg tattggatga tgcactaacg agaaaattag 28740
aaggattggt cttaaaagat attaatggag tatacgaacc gggaaagaga agatggttaa 28800
aaataaagcg agactatttg aacgagggtt ccatggcaga ttctgccgat ttagtagtac 28860
taggtgctta ctatggtaaa ggagcaaagg gtggtatcat ggcagtcttt ctaatgggtt 28920
gttacgacga tgaatccggt aaatggaaga cggttaccaa gtgttcagga cacgatgata 28980
atacgttaag ggttttgcaa gaccaattaa cgatggttaa aattaacaag gatcccaaaa 29040
aaattccaga gtggttggta gttaataaaa tctatattcc cgattttgta gtagaggatc 29100
cgaaacaatc tcagatatgg gaaatttcag gagcagagtt tacatcttcc aagtcccata 29160
ccgcaaatgg aatatccatt agatttccta gatttactag gattagagaa gataaaacgt 29220
ggaaagaatc tactcatcta aacgatttag taaacttgac taaatcttaa tagttacata 29280
caaactgaaa attaaaataa cactatttag ttggtggtcg ccatggatgg tgttattgta 29340
tactgtctaa acgcgttagt aaaacatggc gaggaaataa atcatataaa aaatgatttc 29400
atgattaaac catgttgtga aagagtttgt gaaaaagtca agaacgttca cattggcgga 29460
caatctaaaa acaatacagt gattgcagat ttgccatata tggataatgc ggtatccgat 29520
gtatgcaatt cactgtataa aaagaatgta tcaagaatat ccagatttgc taatttgata 29580
aagatagatg acgatgacaa gactcctact ggtgtatata attattttaa acctaaagat 29640
gttattcctg ttatcatatc tataggaaag gataaagatg tctgtgaact attaatctca 29700
tcagacatat cgtgtgcatg cgtggagtta aattcatatc acgtagccat tcttcccatg 29760
gatgtttcct tttttaccaa aggaaatgca tcattgatta ttctcctgtt tgatttctct 29820
atcgatgcag cacctctctt aagaagtgta accgataata atgttattat atctagacac 29880
cagcgtctac atgacgagct tccgagttcc aattggttca agttttacat aagtataaag 29940
tccgactatt gttctatatt atatatggtt gttgatggat ctgtgatgca tgcgatagct 30000
gataatagaa ctcacgcaat tattagcaaa aatatattag acaatactac gattaacgat 30060
gagtgtagat gctgttattt tgaaccacag attaggattc ttgatagaga tgagatgctc 30120
aatggatcat cgtgtgatat gaacagacat tgtattatga tgaatttacc tgatgtaggc 30180
aaatttggat ctagtatgtt ggggaaatat gaacctgaca tgattaagat tgctctttcg 30240
gtggctggta atttaataag aaatcgagac tacattcccg ggagacgagg atatagctac 30300
tacgtttacg gtatagcctc tagataattt ttttaagcac gaaataaaaa acataatttt 30360
aaaccaatct atttcatact attttgtgtg atcaccatgg acataaagat agatattagt 30420
atttctggtg ataaatttac ggtgactact aggagggaaa atgaagaaag aaaaaaatat 30480
ctacctctcc aaaaagaaaa aactactgat gttatcaaac ctgattatct tgagtacgat 30540
gacttgttag atagagatga gatgtttact attctagagg aatattttat gtacagaggt 30600
ctattaggcc tcagaataaa atatggacga ctctttaacg aaattaaaaa attcgacaat 30660
gatgcggaag aacaattcgg tactatagaa gaactcaagc agaaacttag attaaattct 30720
gaagagggag cagataactt tatagattat ataaaggtac aaaaacagga tatcgtcaaa 30780
cttactgtat acgattgcat atctatgata ggattgtgtg catgcgtggt agatgtttgg 30840
agaaatgaga aactgttttc tagatggaaa tattgtttac gagctattaa actgtttatt 30900
aatgatcaca tgcttgataa gataaaatct atactgcaga atagactagt atatgtggaa 30960
atgtcataga aagttaaaag ttaatgagag caaaaatata taaggttgta ttccatattt 31020
gttatttttt ctgtaatagt tagaaaaata cattcgatgg tctatctacc agattattat 31080
gtgttataag gtactttttc tcataataaa ctagagtatg agtaagatag tgtttttcaa 31140
aacatataaa tctaaaattg atggatgaga tatacagcta ttaatttcga aaatatattt 31200
taatctgata actttaaaca tggatttttg atggtggttt aacgttttaa aaaaagattt 31260
tgttattgta gtatatgata atattaaaag atggatataa agaatttgct gactgcatgt 31320
actatttttt acattactac attggctacg gcagatatac ctactccgcc accaacgggt 31380
catgtgacaa gggagaatat cttgataaga ggcataatca atgttgtaat cggtgtccac 31440
ctggagaatt tgccaaggtt agatgtaatg gtaacgataa cacaaaatgt gaacgctgcc 31500
cacctcatac atataccaca atcccaatta ttctaatgga tgtcatcaat gtagaaaatg 31560
cccaaccgga tcatttgata aggtaaagtg taccggaaca cagaacagta aatgttcgtg 31620
tcttcctggt tggtattgtg ctactgattc ttcacagact gaagattgtt gaaattgtgt 31680
accaaaaagg agatgtccat gcggatactt tggtggaata gatgaacaag gaaatcctat 31740
ttgtaaatcg tgttgtgttg gtgaatattg cgactaccta cgtaattata gacttgatcc 31800
atttcctcca tgcaaactat ctaaatgtaa ttaattatga ttttgatgat aatgttacca 31860
tacattatat cgctacttgg ttagtgtatt attcagtatg aagacctatt aataattact 31920
tatcttttga cgatcttgtt ataattataa tataaaaata cttatggcat agtaactcat 31980
aattgctgac gcgataaatt cgtaataatc tgttttgttc aaatttttat aaggaatcta 32040
caggcataaa aataaaaata taatttataa tatactctta cagcgcgcca tcatgaataa 32100
cagcagtgaa ttgattgctg ttattaatgg atttagaaat agtggacgat tttgtgatat 32160
tagtatagtt attaatgatg aaaggataaa cgctcataaa ctcatcctat ctggagcctc 32220
cgaatatttt tccattctgt tttccaataa ttttatcgat tctaatgaat acgaagttaa 32280
tctaagtcat ttagattatc aaagcgttaa cgatttgatc gattacattt atgggatacc 32340
tttgagccta actaacgata acgtgaaata tattctttca accgctgatt ttttacaaat 32400
tggatctgct attacggagt gtgaaaatta catacttaaa aatctttgtt ctaaaaactg 32460
tatcgatttc tacatatacg ctgataaata taataacaag aaaatagaat cagcgtcgtt 32520
taacacaata ttacaaaata ttttgagact catcaacgat gaaaacttta aatacttaac 32580
agaggaatca atgataaaaa ttttaagcga tgatatgtta aatataaaaa atgaggattt 32640
tgcaccacta attctcatta aatggttaga gagtactcaa caatcatgca ccgtcgagtt 32700
acttagatgc ctcagaatat cattgctttc cccacaagtt ataaaatcac tttatagtca 32760
tcaactggtt agttcaatct acgaatgtat aacattctta aacaatatag cattcttgga 32820
tgaatcattt cctagatacc atagcatcga gttgatatct atcggtataa gtaattcgca 32880
tgataagatt tccataaact gctacaatca taaaaaaaat acatgggaaa tgatatcttc 32940
acgtagatat aggtgtagtt tcgcagtggc cgtcctggat aatattatct atatgatggg 33000
tggatatgat cagtccccgt atagaagttc aaaggttata gcgtacaata catgtacaaa 33060
ttcttggata tatgatatac cagagctaaa atatcctcgt tctaattgtg ggggactggc 33120
tgatgacgaa tacatttatt gtataggcgg catacgcgat caggattcat cgttgacatc 33180
tagtattgat aaatggaagc catcaaaacc atattggcag aagtatgcta aaatgcgcga 33240
accaaaatgt gatatggggg ttgcgatgtt aaacggatta atatatgtca tgggtggaat 33300
cgttaaaggt gacacgtgta ccgacgcact agagagttta tcagaagatg gatggatgaa 33360
gcatcaacgt cttccaataa aaatgtccaa tatgtcgacg attgttcatg atggcaagat 33420
ttatatatct ggaggttaca acaatagtag tgtagttaat gtaatatcga atctagtcct 33480
tagctataat ccgatatatg atgaatggac caaattatca tcattaaaca ttcctagaat 33540
taatcccgct ctatggtcag cgcataataa attatatgta ggaggaggaa tatctgatga 33600
tgttcgaact aatacatctg aaacatacga taaagaaaaa gattgttgga cattggataa 33660
tggtcacgtg ttaccacgca attatataat gtataaatgc gaaccgatta aacataaata 33720
tccattggaa aaaacacagt acacgaatga ttttctaaag tatttggaaa gttttatagg 33780
tagttgatag aacaaaatac ataattttgt aaaaataaat cactttttat actaatatga 33840
cacgattacc aatacttttg ttactaatat cattagtata cgctacacct tttcctcaga 33900
catctaaaaa aataggtgat gatgcaactc tatcatgtaa tcgaaataat acaaatgact 33960
acgttgttat gagtgcttgg tataaggagc ccaattccat tattctttta gctgctaaaa 34020
gcgacgtctt gtattttgat aattatacca aggataaaat atcttacgac tctccatacg 34080
atgatctagt tacaactatc acaattaaat cattgactgc tagagatgcc ggtacttatg 34140
tatgtgcatt ctttatgaca tcaactacaa atgacactga taaagtagat tatgaagaat 34200
actccacaga gttgattgta aatacagata gtgaatcgac tatagacata atactatctg 34260
gatctacaca ttcaccggaa actagttcta agaaacctga ttatatagat aattctaatt 34320
gctcgtcggt attcgaaatc gcgactccgg aaccaattac tgataatgta gaagatcata 34380
cagacaccgt cacatacact agtgatagca ttaatacagt aagtgcatca tctggagaat 34440
ccacaacaga cgagactccg gaaccaatta ctgataaaga agatcataca gttacagaca 34500
ctgtctcata cactacagta agtacatcat ctggaattgt cactactaaa tcaaccaccg 34560
atgatgcgga tctttatgat acgtacaatg ataatgatac agtaccacca actactgtag 34620
gcggtagtac aacctctatt agcaattata aaaccaagga ctttgtagaa atatttggta 34680
ttaccgcatt aattatattg tcggccgtgg caattttctg tattacatat tatatatata 34740
ataaacgttc acgtaaatac aaaacagaga acaaagtcta gatttttgac ttacataaat 34800
gtctgggata gtaaaatcta tcatattgag cggaccatct ggtttaggaa agacagccat 34860
agccaaaaga ctatgggaat atatttggat ttgtggtgtc ccataccact agatttcctc 34920
gtcctatgga acgagaaggt gttgattacc attacgttaa cagagaggcc atctggaagg 34980
gaatagccgc cggaaacttt ctagaacata ctgagttttt aggaaatatt tacggaactt 35040
ctaaaacagc tgtgaataca gcggctatta ataatcgtat ttgtgtgatg gatctaaaca 35100
tcgacggtgt tagaagtctt aaaaatacgt acctaatgcc ttactcggtg tatataagac 35160
ctacctctct taaaatggtt gagaccaagc ttcgttgtag aaacactgaa gctaacgatg 35220
agattcatcg tcgcgtgata ttggcaaaaa cggatatgga tgaggccaac gaagcaggtc 35280
tattcgacac tattatcatt gaagatgatg tgaatttagc atatagtaag ttaattcaga 35340
tactacagga ccgtattaga atgtatttta acactaatta gagacttaag acttaaaact 35400
tgataattaa taatataact cgtttttata tgtggctatt tcaacgtcta atgtattagt 35460
taaatattaa aacttaccac gtaaaactta aaatttaaaa tgatatttca ttgacagata 35520
gatcacacat tatgaacttt caaggacttg tgttaactga caattgcaaa aatcaatggg 35580
tcgttggacc attaatagga aaaggtggat tcggtagtat ttatactact aatgacaata 35640
attatgtagt aaaaatagag cccaaagcta acggatcatt atttaccgaa caggcatttt 35700
atactagagt acttaaacca tccgttatcg aagaatggaa aaaatctcac aatataaagc 35760
acgtaggtct tatcacgtgc aaggcatttg gtctatacaa atccattaat gtggaatatc 35820
gattcttggt aattaataga ttaggtgcag atctagatgc ggtgatcaga gccaataata 35880
atagattacc aaaaaggtcg gtgatgttga tcggaatcga aatcttaaat accatacaat 35940
ttatgcacga gcaaggatat tctcacggag atattaaagc gagtaatata gtcttggatc 36000
aaatagataa gaataaatta tatctagtgg attacggatt ggtttctaaa ttcatgtcta 36060
atggagaaca tgttccattt ataagaaatc caaataaaat ggataacggt actctagaat 36120
ttacacctat agattcgcat aaaggatacg ttgtatctag acgtggagat ctagaaacac 36180
ttggatattg tatgattaga tggttgggag gtatcttgcc atggactaag atatctgaaa 36240
caaagaattg tgcattagta agtgccacaa aacagaaata tgttaacaat actgcgactt 36300
tgttaatgac cagtttgcaa tatgcaccta gagaattgct gcaatatatt accatggtaa 36360
actctttgac atattttgag gaacccaatt atgacgagtt tcggcacata ttaatgcagg 36420
gtgtatatta ttaagtgtgg tgtttggtcg atgtaaaatt tttgtcgata aaaattaaaa 36480
aataacttaa tttattattg atctcgtgtg tacaaccgaa atcatggcga tgttttacgc 36540
acacgctctc ggtgggtacg acgagaatct tcatgccttt cctggaatat catcgactgt 36600
tgccaatgat gtcaggaaat attctgttgt gtcagtttat aataacaagt atgacattgt 36660
aaaagacaaa tatatgtggt gttacagtca ggtgaacaag agatatattg gagcactgct 36720
gcctatgttt gagtgcaatg aatatctaca aattggagat ccgatccatg atcaagaagg 36780
aaatcaaatc tctatcatca catatcgcca caaaaactac tatgctctaa gcggaatcgg 36840
gtacgagagt ctagacttgt gtttggaagg agtagggatt catcatcacg tacttgaaac 36900
aggaaacgct gtatatggaa aagttcaaca tgattattct actatcaaag agaaggccaa 36960
agaaatgaat gcacttagtc caggacctat cattgattac cacgtctgga taggagattg 37020
tatctgtcaa gttactgctg tggacgtaca tggaaaggaa attatgagaa tgagattcaa 37080
aaagggtgcg gtgcttccga tcccaaatct ggtaaaagtt aaacttgggg agaatgatac 37140
agaaaatctt tcttctacta tatcggcggc accatcgagg taaccacctc tctggaagac 37200
agcgtgaata atgtactcat gaaacgtttg gaaactatac gccatatgtg gtctgtcgta 37260
tatgatcatt ttgatattgt gaatggtaaa gaatgctgtt atgtgcatac gcatttgtct 37320
aatcaaaatc ttataccgag tactgtaaaa acaaatttgt acatgaagac tatgggatca 37380
tgcattcaaa tggattccat ggaagctcta gagtatctta gcgaactgaa ggaatcaggt 37440
ggatggagtc ccagaccaga aatgcaggaa tttgaatatc cagatggagt ggaagacact 37500
gaatcaattg agagattggt agaggagttc ttcaatagat cagaacttca ggctggtgaa 37560
tcagtcaaat ttggtaattc tattaatgtt aaacatacat ctgtttcagc taagcaacta 37620
agaacacgta tacggcagca gcttccttta tactctcatc ttttaccaac acaaagggtg 37680
gatatttgtt cattggagtt gataataata cacacaaagt aattggattc acggtgggtc 37740
atgactacct cagactggta gagaatgata tagaaaagca tatcaaaaga cttcgtgttg 37800
tgcatttctg tgagaagaaa gaggacatca agtacacgtg tcgattcatc aaggtatata 37860
aacctgggga tgaggctacc tcgacatacg tgtgcgctat caaagtggaa agatgctgtt 37920
gtgctgtgtt tgcagattgg ccagaatcat ggtatatgga tactaatggt atcaagaagt 37980
attctccaga tgaatgggtg tcacatataa aattttaatt aatgtaatag agaacaaata 38040
ataaggttgt aatatcatat agacaataac taacaattaa ttagtaactg ttatctcttt 38100
tttaactaac caactaacta tatacctatt aatacatcgt aattatagtt cttaacatct 38160
attaatcatt aattcgcttc tttaattttt tataaactaa cattgttaat tgaaaaggga 38220
taacatgtta cagaatataa attatatatg gattttttta aaaaggaaat acttgactgg 38280
agtatatatt tatctcttca ttatatagca cgcgtgtttt ccaatttttc cacatcccat 38340
ataatacagg attataatct cgttcgaaca tacgagaaag tggataaaac aatagttgat 38400
tttttatcta ggttgccaaa tttattccat attttagaat atggggaaaa tattctacat 38460
atttattcta tggatgatgc taatacgaat attataattt tttttctaga tagagtatta 38520
aatattaata agaacgggtc atttatacac aatctcaggt tatcatcatc cattaatata 38580
aaagaatatg tatatcaatt agttaataat gatcatccag ataataggat aagactaatg 38640
cttgaaaatg gacgtagaac aagacatttt ttgtcctata tatcagatac agttaatatc 38700
tatatatgta ttttaataaa tcatggattt tatatagatg ccgaagacag ttacggttgt 38760
acattattac atagatgtat atatcactat aagaaatcag aatcagaatc atacaatgaa 38820
ttaattaaga tattgttaaa taatggatca gatgtagata aaaaagatac gtacggaaac 38880
acacctttta tcctattatg taaacacgat atcaacaacg tggaattgtt tgagatatgt 38940
ttagagaatg ctaatataga ctctgtagac tttaatagat atacacctct tcattatgtc 39000
tcatgtcgta ataaatatga ttttgtaaag ttattaattt ctaaaggagc aaatgttaat 39060
gcgcgtaata gattcggaac tactccattt tattgtggaa ttatacacgg tatctcgctt 39120
ataaaactat atttggaatc agacacagag ttagaaatag ataatgaaca tatagttcgt 39180
catttaataa tttttgatgc tgttgaatct ttagattatc tattatccag aggagttatt 39240
gatattaact atcgtactat atacaacgaa acatctattt acgacgctgt cagttataat 39300
gcgtataata cgttggtcta tctattaaac agaaatggtg attttgagac gattactact 39360
agtggatgta catgtatttc ggaagcagtc gcaaacaaca acaaaataat aatggaagta 39420
ctattgtcta aacgaccatc tttgaaaatt atgatacagt ctatgatagc aattactaaa 39480
cataaacagc ataatgcaga tttattgaaa atgtgtataa aatatactgc gtgtatgacc 39540
gattatgata ctcttataga tgtacagtcg ctacagcaat ataaatggta tattttaaaa 39600
tgtttcgatg aaatagatat catgaagaga tgttatataa aaaataaaac tgtattccaa 39660
ttagtttttt gtatcaaaga cattaatact ttaatgagat acggtaaaca tccttctttc 39720
gtgaaatgca ctagtctcga cgtatacgga agtcgtgtac gtaatatcat agcatctatt 39780
agatatcgtc agagattaat tagtctatta tccaagaagc tggatcctgg agataaatgg 39840
tcgtgttttc ctaacgaaat aaaatataaa atattggaaa actttaacga taacgaacta 39900
tccacatatc taaaaatctt ataaacacta ttaaaatata aaatctaagt aggataaaat 39960
cacactacat cattgtttcc ttttagtgct cgacagtgta tactattttt aacactcata 40020
aataaaaatg aaaacgattt ccgttgttac gttgttatgc gtactacctg ctgttgttta 40080
ttcaacatgt actgtaccca ctatgaataa cgctaaatta acgtctaccg aaacatcgtt 40140
taatgataaa cagaaagtta cgtttacatg tgatcaggga tatcattctt cggatccaaa 40200
tgctgtctgc gaaacagata aatggaaata cgaaaatcca tgcaaaaaaa tgtgcacagt 40260
ttctgattac atctctgaat tatataataa accgctatac gaagtgaatt ccaccatgac 40320
actaagttgc aacggcgaaa caaaatattt tcgttgcgaa gaaaaaaatg gaaatacttc 40380
ttggaatgat actgttacgt gtcctaatgc ggaatgtcaa cctcttcaat tagaacacgg 40440
atcgtgtcaa ccagttaaag aaaaatactc atttggggaa tatatgacta tcaactgtga 40500
tgttggatat gaggttattg gtgcttcgta cataagttgt acagctaatt cttggaatgt 40560
tattccatca tgtcaacaaa aatgtgatat gccgtctcta tctaatggat taatttccgg 40620
atctacattt tctatcggtg gcgttataca tcttagttgt aaaagtggtt ttacactaac 40680
ggggtctcca tcatccacat gtatcgacgg taaatggaat cccgtactcc caatatgtgt 40740
acgaactaac gaagaatttg atccagtgga tgatggtccc gacgatgaga cagatttgag 40800
caaactctcg aaagacgttg tacaatatga acaagaaata gaatcgttag aagcaactta 40860
tcatataatc atagtggcgt taacaattat gggcgtcata tttttaatct ccgttatagt 40920
attagtttgt tcctgtgaca aaaataatga ccaatataag ttccataaat tgctaccgta 40980
aatataaatc cgttaaaata atgaataatt aataacgaac aagtatcaaa agattaaaga 41040
attatagcta gaatcaattg agatgtcttc ttcagtggat gttgatatct acgatgccgt 41100
tagagcattt ttactcaggc actattataa caagagattt attgtgtatg gaagaagtaa 41160
cgccatatta cataatatat acaggctatt tacaagatgc gccgttatac cgttcgatga 41220
tatagtacgt actatgccaa atgaatcacg tgttaaacaa tgggtgatgg atacacttaa 41280
tggtataatg atgaatgaac gcgatgtttc tgtaagcgtt ggcaccggaa tactattcat 41340
ggaaatgttt ttcgattaca ataaaaatag tatcaacaat caactaatgt atgatataat 41400
taatagcgta tctataattc tagctaatga gagatataga agcgctttta acgacgatgg 41460
tatatacatc cgtagaaata tgattaacaa gttgtacgga tacgcatctc taactactat 41520
tggcacgatc gctggaggtg tttgttatta tctgttgatg catctagtta gtttgtataa 41580
ataattattt caatatacta gttaaaattt taagatttta aatgtataaa aaactaataa 41640
cgtttttatt tgtaataggt gcattagcat cctattcgaa taatgagtac actccgttta 41700
ataaactgag tgtaaaactc tatatagatg gagtagataa tatagaaaat tcatatactg 41760
atgataataa tgaattggtg ttaaatttta aagagtacac aatttctatt attacagagt 41820
catgcgacgt cggatttgat tccatagata tagatgttat aaacgactat aaaattattg 41880
atatgtatac cattgactcg tctactattc aacgcagagg tcacacgtgt agaatatcta 41940
ccaaattatc atgccattat gataagtacc cttatattca caaatatgat ggtgatgagc 42000
gacaatattc tattactgca gagggaaaat gctataaagg aataaaatat gaaataagta 42060
tgatcaacga tgatactcta ttgagaaaac atactcttaa aattggatct acttatatat 42120
ttgatcgtca tggacatagt aatacatatt attcaaaata tgatttttaa aaatttaaaa 42180
tatattatca cttcagtgac agtagtcaaa taacaaacaa caccatgaga tatattataa 42240
ttctcgcagt tttgttcatt aatagtatac acgctaaaat aactagttat aagtttgaat 42300
ccgtcaattt tgattccaaa attgaatgga ctggggatgg tctatacaat atatccctta 42360
aaaattatgg catcaagacg tggcaaacaa tgtatacaaa tgtaccagaa ggaacatacg 42420
acatatccgc atttccaaag aatgatttcg tatctttctg ggttaaattt gaacaaggcg 42480
attataaagt ggaagagtat tgtacgggac tatgcgtcga agtaaaaatt ggaccaccga 42540
ctgtaacatt gactgaatac gacgaccata tcaatttgta catcgagcat ccgtatgcta 42600
ctagaggtag caaaaagatt cctatttaca aacgcggtga catgtgtgat atctacttgt 42660
tgtatacggc taacttcaca ttcggagatt ctaaagaacc agtaccatat gatatcgatg 42720
actacgattg cacgtctaca ggttgcagca tagactttgt cacaacagaa aaagtgtgcg 42780
tgacagcaca gggagccaca gaagggtttc tcgaaaaaat tactccatgg agttcgaaag 42840
tatgtctgac acctaaaaag agtgtatata catgcgcaat tagatccaaa gaagatgttc 42900
ccaatttcaa ggacaaaatg gccagagtta tcaagagaaa atttaataaa cagtctcaat 42960
cttatttaac taaatttctc ggtagcacat caaatgatgt taccactttt cttagcatgc 43020
ttaacttgac taaatattca taactaattt ttattaatga tacaaaaacg aaataaaact 43080
gcatattata cactggttaa cgcccttata ggctctaacc attttcaaga tgaggtccct 43140
gattatagtc cttctgttcc cctctatcat ctactccatg tctattagac aatgtgagaa 43200
gactgaagag gaaacatggg gattgaaaat agggttgtgt ataattgcca aagatttcta 43260
tcccgaaaga actgattgca gtgttcatct cccaactgca agtgaaggat tgataactga 43320
aggcaatgga ttcagggata tacgaaacac cgataaatta taaaaaaagc aatgtgtccg 43380
ctgtttccgt taataatact attttcgtaa ctggcggatt attcataaat aactctaata 43440
gcacgatcgt ggttaacaat atggaaaaac ttgacattta taaagacaaa caatggtcga 43500
ttatagaaat gcctatggct agggtatatc acggcatcga ctcgacattt ggaatgttat 43560
attttgccgg aggtctatcc gttaccgaac aatatggtaa tttagagaaa aacaacgaga 43620
tatcttgtta caatcctaga acgaataagt ggtttgatat ttcatatact atttataaga 43680
tatccatatc atcattgtgt aaactaaata acgtcttcta tgtatttagt aaggacattg 43740
gatatgtgga aaagtatgat ggtgcatgga agttagtaca tgatcgtctc cccgctataa 43800
aggcattatc aacttctcct tattgattga aaatgaaaat ataaatagtt tttatgtata 43860
gcagtattac cctatagttt tattgcttac tactaacatg gatacagatg ttacaaatgt 43920
agaagatatc ataaatgaaa tagatagaga gaaagaagaa atactaaaaa atgtagaaat 43980
tgaaaataat aaaaacatta acaagaatca tccaagtgga tatattagag aagcactcgt 44040
tattaatacc agtagtaata gtgattccat tgataaagaa gttatagaat gtatctgtca 44100
cgatgtagga atatagatca tatctactaa tttttataat cgatacaaaa cataaaaaac 44160
aactcgttat tacatagcag gcatggaatc cttcaagtat tgttttgata acgatggcaa 44220
gaaatggatt atcggaaata ctttatattc tggtaattca atactatata aggtcagaaa 44280
aaatttcact agttcgttct acaattacgt aatgaagata gatcacaaat cacacaagcc 44340
attgttgtct gaaatacgat tctatatatc tgtattggat cctttgacta tcgacaactg 44400
gacacgggaa cgtggtataa agtatttggc tattccagat ctgtatggaa ttggagaaac 44460
cgatgattat atgttcttcg ttataaagaa tttgggaaga gtattcgccc caaaggatac 44520
tgaatcagtc ttcgaagcat gcgtcactat gataaacacg ttagagttta tacactctca 44580
aggatttacc catggaaaaa tagaaccgag gaatatactg attagaaata aacgtctttc 44640
actaattgac tattctagaa ctaacaaact atacaagagt ggaaactcac atatagatta 44700
caacgaggac atgataactt caggaaatat caattatatg tgtgtagaca atcatcttgg 44760
agcaacagtt tcaagacgag gagatttaga aatgttggga tattgcatga tagaatggtt 44820
cggtggcaaa cttccatgga aaaacgaaag tagtataaaa gtaataaaac aaaaaaaaga 44880
atataaaaaa tttatagcta ctttctttga ggactgtttt cctgaaggaa atgaacctct 44940
ggaattagtt agatatatag aattagtata cacgttagat tattctcaaa ctcctaatta 45000
tgacagacta cgtaaactgt ttatacaaga ttgaaattat attctttttt ttatagagtg 45060
tggtagtgtt acggatattt aatattagac tatctctatc gcgctacacg accaatatcg 45120
attactatgg atatcttcag ggaaatcgca tcttctatga aaggagagaa tgtattcatt 45180
tctccagcgt caatctcgtc agtattgaca atactgtatt atggagctaa tggatccact 45240
gctgaacagc tatcaaaata tgtagaaaag gaggagaaca tggataaggt tagcgctcaa 45300
aatatctcat tcaaatccat aaataaagta tatgggcgat attctgccgt gtttaaagat 45360
tcctttttga gaaaaattgg cgataagttt caaactgttg acttcactga ttgtcgcact 45420
atagatgcaa tcaacaagtg tgtagatatc tttactgagg ggaaaatcaa tccactattg 45480
gatgaaccat tgtctcctga tacctgtctc ctagcaatta gtgccgtata ctttaaagca 45540
aaatggttga cgccattcga aaaggaattt accagtgatt atccctttta cgtatctccg 45600
acggaaatgg tagatgtaag tatgatgtct atgtacggca aggcatttaa tcacgcatct 45660
gtaaaggaat cattcggcaa cttttcaatc atagaactgc catatgttgg agatactagt 45720
atgatggtca ttcttccaga caagattgat ggattagaat ccatagaaca aaatctaaca 45780
gatacaaatt ttaagaaatg gtgtaactct ctggaagcta cgtttatcga tgttcacatt 45840
cccaagttta aggtaacagg ctcgtataat ctggtggata ctctagtaaa gtcaggactg 45900
acagaggtgt tcggttcaac tggagattat agcaatatgt gtaattcaga tgtgagtgtc 45960
gacgctatga tccacaaaac gtatatagat gtcaatgaag agtatacaga agcagctgca 46020
gcaacttgtg cactggtgtc agactgtgca tcaacaatta caaatgagtt ctgtgtagat 46080
catccgttca tctatgtgat taggcatgtt gatggaaaaa ttcttttcgt tggtagatat 46140
tgctctccga caactaattg ttaaccattt tttttaaaaa atagaaaaaa catgtggtat 46200
tagtgcaggt cgttattctt ccaattgcaa ttggtaagat gacggccaac tttagtaccc 46260
acgtcttttc accacagcac tgtggatgtg acagactgac cagtattgat gacgtcagac 46320
aatgtttgac tgaatatatt tattggtcgt cctatgcata ccgcaacagg caatgcgctg 46380
gacaattgta ttccacactc ctctctttta gagatgatgc ggaattagtg ttcatcgaca 46440
ttcgcgagct ggtaaaaaat atgccgtggg atgatgtcaa agattgtgca gaaatcatcc 46500
gttgttatat accggatgag caaaaaacca tcagagagat ttcggccatc atcggacttt 46560
gtgcatatgc tgctacttac tggggaggtg aagaccatcc cactagtaac agtctgaacg 46620
cattgtttgt gatgcttgag atgctcaatt acgtggatta taacatcata ttccggcgta 46680
tgaattgatg agttgtacat cttgacattt tcttctttct tctcttctcc ctttcccaga 46740
aacaaacttt ttttacccac tataaaataa aatgagtata ctacctgtta tatttctttc 46800
tatatttttt tattcttcat tcgttcagac ttttaacgcg cctgaatgta tcgacaaagg 46860
gcaatatttt gcatcattca tggagttaga aaacgagcca gtaatcttac catgtcctca 46920
aataaatacg ctatcatccg gatataatat attagatatt ttatgggaaa aacgaggagc 46980
ggataatgat agaattatac cgatagataa tggtagcaat atgctaattc tgaacccgac 47040
acaatcagac tctggtattt atatatgcat taccacgaac gaaacctact gtgacatgat 47100
gtcgttaaat ttgacaatcg tgtctgtctc agaatcaaat atagatctta tctcgtatcc 47160
acaaatagta aatgagagat ctactggcga aatggtatgt cccaatatta atgcatttat 47220
tgctagtaac gtaaacgcag atattatatg gagcgggcat cgacgcctta gaaataagag 47280
acttaaacaa cggacacctg gaattattac catagaagat gttagaaaaa atgatgctgg 47340
ttattataca tgtgttttag aatatatata cggtggcaaa acatataacg taaccagaat 47400
tgtaaaatta gaggtacggg ataaaataat accttctact atgcaattac cagatggcat 47460
tgtaacttca ataggtagta atttgactat tgcatgcaga gtatcgttga gacctcccac 47520
aacggatgca gacgtctttt ggataagtaa tggtatgtat tacgaagaag atgatgggga 47580
cggaaacggt agaataagtg tagcaaataa aatctatatg accgataaga gacgtgttat 47640
tacatcccgg ttaaacatta atcctgtcaa ggaagaagat gctacaacgt ttacgtgtat 47700
ggcgtttact attcctagca tcagtaaaac agttactgtt agtataacgt gaatgtatgt 47760
tgttacattt ccatgtcaat tgagtttata agaattttta tacattatct tccaacaagc 47820
aattgacgaa cgtattgcta tgattaactc ccacgatact atgcatatta ttaatcatta 47880
acttgcagac tatacctaga gctattttga catactcgtg ttcttgtgta attgcagtat 47940
ctatattatt aaagtacgta aatctagcta tagttttatt atttaatttt agataatata 48000
ccgtctcctt atttttaaaa attgccacat cctttattaa atcatgaatg ggaatttcta 48060
tgtcatagtt aatatattgt gaacaacaag agcagatatc tataggaaag ggtggaatgc 48120
gatacattga tctatgtagt tttaaaacac acgcaaactt tgaagaattt atataaatca 48180
ttccatcgat acatccttct atgttgagat gtatatatcc aggaattcgt ttattaatat 48240
cgggaaatgt ataaactaaa acattgcccg gaagcggagc ttctaccgga gttatatcag 48300
tttttaactt acaaaatgta accaatacct ttgcatgact tgttttgttc ggcaacgtta 48360
gtttaaactt gacgaatgga ttaattacaa tagcatgatc cgcgcatcta ttaagttttt 48420
ttactttaac gcccttgtat gtttttacag agactttatc taaatttcta gtgcttgtat 48480
gtgttataaa tataacggga tatagaactg aatcacctac cttagatacc caattacatt 48540
ttatcagatc cagataataa acaaattttg tcgccctaac taattctata ttgttatata 48600
ttttacaatt ggttatgata tcatgtaata acttggaatc taacgcacat cgtcgtacgt 48660
ttatacaatt gtgatttagt gtagtatatc tacacatgta tttttccgcg ctatagtatt 48720
ctggactagt gataaaacta tcgttatatc tgtcttcaat gaactcatcg agatattgct 48780
ctctgtcata ttcatacacc tgcataaact ttctagacat cttacaatcc gtgttatttt 48840
aggatcatat ttacatattt acgggtatat caaagatgtt agattagtta atgggaatcg 48900
tctataataa tgaatattaa acaattatat gaggactttt accacaaagc atcataaaaa 48960
tgagtcgtcg tctgatttat gttttaaata tcaaccgcga atcaactcat aaaatacaag 49020
agaatgaaat atatacatat tttagtcatt gcaatataga ccatacttct acagaacttg 49080
attttgtagt taaaaactat gatctaaaca gacgacaacc tgtaactggg tatactgcac 49140
tacactgcta tttgtataat aattacttta caaacgatgt actgaagata ttattaaatc 49200
atggagtgga tgtaacgatg aaaaccagta gcggacgtat gcctgtttat atattgctta 49260
ctagatgttg caatatttca catgatgtag tgatagatat gatagacaaa gataaaaacc 49320
acttattaca tagagactat tccaacctat tactagagta tataaaatct cgttacatgt 49380
tattaaagga agaggatatc gatgagaaca tagtatccac tttattagat aagggaatcg 49440
atcctaactt taaacaagac ggatatacag cgttacatta ttattatttg tgtctcgcac 49500
acgtttataa accaggtgag tgtagaaaac cgataacgat aaaaaaggcc aagcgaatta 49560
tttctttgtt tatacaacat ggagctaatc taaacgcgtt agataattgt ggtaatacac 49620
cattccattt gtatcttagt attgaaatgt gtaataatat tcatatgact aaaatgctgt 49680
tgacttttaa tccgaatttc gaaatatgta ataatcatgg attaacgcct atactatgtt 49740
atataacttc cgactacata caacacgata ttcttgttat gttaatacat cactatgaaa 49800
caaatgttgg agaaatgccg atagatgagc gtcgtataat cgtattcgag tttatcaaaa 49860
catattctac acgtcctgca gattcgataa cttatttgat gaataggttt aaaaatatag 49920
atatttatac ccgctatgaa ggaaagacat tattacacgt agcatgtgaa tataataata 49980
cacacgtaat agattatctt atacgtatca acggagatat aaatgcgtta accgacaata 50040
acaaacacgc tacacaactc attatagata acaaagaaaa ttccccatat accattaatt 50100
gtttactgta tatacttaga tatattgtag ataagaatgt gataagatcg ttggtggatc 50160
aacttccatc tctacctatc ttcgatataa aatcatttga gaaattcata tcctactgta 50220
tacttttaga tgacacattt tacaatagac acgttaggaa tcgcgattct aaaacgtatc 50280
gatacgcatt ttcaaaatac atgtcgtttg ataaatacga tggtataata actaaatgtc 50340
ataaagaaac aatattgctc aaactatcca ctgttctaga cactacacta tatgcagttt 50400
taagatgcca taattcgaaa aagttaagaa gatacctcac cgagttaaaa aaatataata 50460
acgataagtc ctttaaaata tattctaata ttatgaatga gagatacctt aatgtatatt 50520
ataaagatat gtacgtgtca aaggtatatg ataaactatt tcctgttttc acagataaaa 50580
attgtctact aacattacta ccttcagaaa ttatatacga aatattatac atgctgacaa 50640
ttaacgatct ttataatata tcgtatccac ctaccaaagt atagttgtat ttttctcatg 50700
cgatgtgtgt aaaaaaactg atattatata aatattttag tgccgtataa taaagatgac 50760
gatgaaaatg atggtacata tatatttcgt atcattattg ttattgctat tccacagtta 50820
cgccatagac atcgaaaatg aaatcacaga attcttcaat aaaatgagag atactctacc 50880
agctaaagac tctaaatggt tgaatccagc atgtatgttc ggaggcacaa tgaatgatat 50940
agccgctcta ggagagccat tcagcgcaaa gtgtcctcct attgaagaca gtcttttatc 51000
gcacagatat aaagactatg tggttaaatg ggaaaggcta gaaaaaaata gacggcgaca 51060
ggtttctaat aaacgtgtta aacatggtga tttatggata gccaactata catctaaatt 51120
cagtaaccgt aggtatttgt gcaccgtaac tacaaagaat ggtgactgtg ttcagggtat 51180
agttagatct catattagaa aacctccttc atgcattcca aaaacatatg aactaggtac 51240
tcatgataag tatggcatag acttatactg tggaattctt tacgcaaaac attataataa 51300
tataacttgg tataaagata ataaggaaat taatatcgac gacattaagt attcacaaac 51360
gggaaaggaa ttaattattc ataatccaga gttagaagat agcggaagat acgactgtta 51420
cgttcattac gacgacgtta gaatcaagaa tgatatcgta gtatcaagat gtaaaatact 51480
tacggttata ccgtcacaag accacaggtt taaactaata ctagatccaa aaatcaacgt 51540
aacgatagga gaacctgcca atataacatg cactgctgtg tcaacgtcat tattgattga 51600
cgatgtactg attgaatggg aaaatccatc cggatggctt ataggattcg attttgatgt 51660
atactctgtt ttaactagta gaggcggtat taccgaggcg accttgtact ttgaaaatgt 51720
tactgaagaa tatataggta atacatataa atgtcgtgga cacaactatt attttgaaaa 51780
aacccttaca actacagtag tattggagta aatatacaat gcatttttat atacattact 51840
gaataattat tattattatt tatatcgtat ttgtgctata acgcgactat ctaggtattt 51900
gtatctcacc gatagagaac atataaatgt agactctatt aaacagttgt gtaaaatatc 51960
agatcctaat gcatgttata gatgtggatg tacggcttta catgagtact tttataatta 52020
tagatcagtc aacggaaaat acaagtatag atacaacggt tactatcaat attatttatc 52080
tagcgattat gaaaattata atgaatatta ttatgatgat tatgatagaa ctggtatgaa 52140
cagtgagagt gataatatat caatcaaaac agaatatgaa ttctatgatg aaacacaaga 52200
tcaaagtaca caactagtag gttacgacat taaactcaaa accaatgagg atgattttat 52260
ggctatgata gatcagtggg tgtccatgat tatatagatg aatcaattaa taaagtagta 52320
tatggaagag agtctcacgt aagatggcgg gatatatggc aagaacataa tgatggcgta 52380
tacagtatag gaaaggagtg catagataat atatacgaag acaaccatac cgtagacgaa 52440
ttctacaaga tagacagcgt atcagatgta gatgacgcgg aacacatatc tccgataact 52500
aatgatgtat ctacacaaac atgggaaaag aaatcagagt tagatagata catggaaatg 52560
tatcctcgtc atagatatag taagcattct gtctttaagg gattttctga caaagttaga 52620
aaaaatgatt tagacatgaa tgtggtaaaa gaattacttt ctaacggtgc atctctaaca 52680
attaaggata gcagtaataa ggatccaata accgtttatt ttcgaagaac gataatgaat 52740
ttagaaatga ttgatgaacg aaagtatata gtacactcct atctaaaaaa ttataaaaat 52800
ttcgattatc catttttcag gaagttagtt ttgactaata aacattgtct caacaattat 52860
tataatataa gcgacagcaa atatggaaca ccgctacata tattggcgtc taataaaaaa 52920
ttaataactc ctaattacat gaagttatta gtgtataacg gaaatgatat aaacgcacga 52980
ggtgaagata cacaaatgcg aactccatta cacaaatatt tgtgtaaatt tgtatatcat 53040
aatattgaat atggtatccg atactataat gaaaagatta tagacgcatt tatagagtta 53100
ggagccgatc taactattcc aaatgacgat ggaatgatac cagtagttta ctgtatacac 53160
tcaaatgccg aatatggtta taacaatatt actaacataa agataatacg taaactactt 53220
aatcttagta gacgtgcgtc acataatcta tttagagatc gagtcatgca cgattatata 53280
agtaatacat atattgatct tgagtgttta gatattatta gatcgttgga tggattcgat 53340
atcaatggtt actttgaagg acgtacacca cttcattgcg ctatacaaca taacttcact 53400
cagattgcta agtacttatt agatcgagga gctgatatag tcgtacccaa cacattgatt 53460
atacatcagt acatacagta aatagcatag atatggagga ggatacaaat atttcaaata 53520
aagttataag gtacaacact gtcaataata tatgggaaac attacctaac ttctggactg 53580
gaactataaa tccaggcgtg gtctcgcata aagatgatat atatgttgta tgcgacatca 53640
aagatgaaaa aaatgttaaa acttgtatat ttagatataa cacgaatacg tataacggat 53700
gggaattggt cacgacgaca gaaagcagat tatcagctct gcatactatt ctttataaca 53760
ataccataat gatgttacat tgttatgaat cgtatatgtt acaagataca tttaatgtgt 53820
acactcgcga atggaatcat atgtgtcatc aacattcgaa tagttatatc atgtacaata 53880
tactacccat ctactaaata taatagaata aaataaatga gtatgatcat tttagataac 53940
gattgatttt atcattaccg cttcattctt atattctttg cttacggaac ctatatttag 54000
aaacatctac taacgatttt ttatgcttgc attattaatg gtatgtaata tgattgattg 54060
tgtacgcaat accaatttgt taagtatgaa tacggggtac aaacataaac tgaagtttaa 54120
cattatttat ttatgatata tatcgttatt gtttggtcta taccatggat atctttaaag 54180
aactaatctt aaaacacacg gatgaaaatg ttttgatttc tccagtttct attttatcta 54240
ctttatctat tctaaatcat ggagcagctg gttctacagc tgaacaacta tcaaaatata 54300
tagagaatat gaatgagaat acacccgatg acaataatga catggacgta gatattccgt 54360
attgtgcgac actagctacc gcaaataaaa tatacggtag cgatagtatc gagttccacg 54420
cctccttcct acaaaaaata aaagacgatt ttcaaactgt aaactttaat aatgctaacc 54480
aaacaaagga actaatcaac gaatgggtta agacaatgac aaatggtaaa attaattcct 54540
tattgactag tccgctatcc attaatactc gtatgacagt tgttagcgcc gtccatttta 54600
aagcaatgtg gaaatatcca ttttctaaac atcttacata tacagacaag ttttatattt 54660
ctaagaatat agttaccagt gttgatatga tggtgagcac tgagaataac ttgcaatatg 54720
tacatattaa tgaattattc ggaggattct ctattatcga tattccatac gagggaaact 54780
ctagtatggt aattatacta ccggacgaca tagaaggtat atataacata gaaaaaaata 54840
taacagatga aaaatttaaa aaatggtgtg gtatgttatc tactaaaagt atagacttgt 54900
atatgccaaa gtttaaagtg gaaatgacag aaccgtataa tctggtaccg attttagaaa 54960
atttaggact tactaatata ttcggatatt atgcagattt tagcaagatg tgtaatgaaa 55020
ctatcactgt agaaaaattt ctacatacga cgtttataga tgttaatgag gagtatacag 55080
aagcatcggc cgttacagga gtatttatga ctaacttttc gatggtatat cgtacgaagg 55140
tctacataaa ccatccattc atgtacatga ttaaagacaa cacaggacgt atacttttta 55200
tagggaaata ctgctatccg caataaatat aaacaaatag acttttatca cgtttatcta 55260
tgtctaaata ttacaaatag taatagtata aactaaagct gataatactt aaaaaaataa 55320
taatatcatt tacaattaat agtataaact aaaaattaaa caaatcgtta ttataagtaa 55380
tatcaaaatg atgatatacg gattaatagc gtgtcttata ttcgtgactt catccatcgc 55440
tagtccactt tatattcccg ttattccacc catttcggaa gataaatcgt tcaatagtgt 55500
agaggtatta gtttccttgt ttagagatga ccaaaaagac tatacggtaa cttctcagtt 55560
caataactac actatcgata ccaaagactg gactatcggc gtactatcca cacctgatgg 55620
tttggatata ccattgacta atataactta ttggtcacgg tttactatag gtcgtgcatt 55680
gttcaaatca gagtctgagg atattttcca aaagaaaatg agtattctag gtgtttctat 55740
agaatgtaag aagtcgtcga cattacttac ttttttgacc gtgcgtaaaa tgactcgagt 55800
atttaataaa tttccagata tggcttatta tcgaggagac tgtttaaaag ccgtttatgt 55860
aacaatgact tataaaaata ctaaaactgg agagactgat tacacgtacc tctctaatgg 55920
ggggttgcct gcatactatc gtaatggggt cgatggttga ttattgatta gtatattcct 55980
tattcttttt attcacacaa aaagaacatt tttataaaca tgaaaccact gtctaaatgt 56040
aattatgatc ttgatttata gatgaagatc agcctttaga ggattttaac cagtatgttt 56100
aatatgaaaa aaataaacat aacatatttt gagattaagc gctattgtgc aagattatat 56160
tagaatcaaa ttaatctttc atacgagaaa aataacgaca tacgtcgtca acaaattaaa 56220
ctttttattt attagttaac tagcttatag aacttgctca ttgttatgtt tctaaaacgg 56280
gtacgacata taggacaatt atccgacgca ccggtttctc ttcgtgtttt atgccatata 56340
ttgatgcatg ttatgcaaaa tatatgagta cacgaatcca ataaaccaaa gtatctatcg 56400
ttttgagtaa acaacttcat agcaaattcc acattctttt tctttactta ctctatacac 56460
gtcctcgtat ttatccagta ttttgatgat atccaactca gaaatggttg ttgtattatt 56520
gggtgtattg ggagtatagg tattattagc tatgtaccaa tttaccaacc ctcttaatat 56580
tgattgaaca atcacatcgg ttatccaatc aataaccaca ttaataacta aattgtagtg 56640
tatatataga ccatatatgt ttctattttt ttgacagtta cgtatagttt cagtaagttt 56700
tgattgttgt attcctgtat ctctagataa gttagtcata tagtcccttc cggcgatacg 56760
ttttttccaa gcccgaaatt gattagccaa atgtgtattt atttttgtga tattgatata 56820
atatgtaatg ttattaatat ttcggataat gcatactgtt agtcttatat catttggttc 56880
atctatgtat tgtaatattg ttacatgatc tatagatgat gtattgattt tggcaggatc 56940
gaattccata tccgcgacta aacagtgaaa aaaatgtaaa tactttttaa attttaaatt 57000
agtaaaactt ttttttattt tttatgattc caaaaatact gaatacaaag tcctaaatta 57060
taaatatgga gatcatacta ccacaactta ttattatgca tactcagccg gtgtaataga 57120
tagatatata taattctatt acaccggcag acaattaccg atcggtattt gtcgttacca 57180
acataccgta taatatgtaa tatacaattc cataacccat tgacagttgt tatacatcaa 57240
aattgcaatt cttttgatta cgatgttata agaatgtagt taattgatgt atgatgttaa 57300
tgtgtcctct ttcctcttat aacatcgtaa tcaaaaactt ttttataata tatacctaat 57360
aatgtgtctt aatagttctc gtgattcgtc aaacaatcat tcttataaaa tataataaag 57420
caacgtaaaa cacataaaaa taagcgtaac taataagaca atggatattt acgacgataa 57480
aggtctacag actattaaac tgtttaataa tgaatttgat tgtataagga atgacatcag 57540
agaattattt aaacatgtaa ctgattccga tagtatacaa cttccgatgg aagacaattc 57600
tgatattata gaaaatatca gaaaaatact atatagacga ttaaaaaatg tagaatgtgt 57660
tgacatcgat agtacaataa cttttatgaa atacgatcca aatgatgata ataagcgtac 57720
gtgttctaat tgggtaccct taactaataa ctatatggaa tattgtctag taatatattt 57780
ggaaacaccg atatgtggag gcaaaataaa attataccac cctacaggaa atataaagtc 57840
ggataaggat attatgtttg caaagactct agactttaaa tcaaagaaag tgttaactgg 57900
acgtaaaaca attgccgttc tagacatatc cgtttcatat aatagatcaa tgactactat 57960
tcactacaac gacgacgttg atatagatat acatactgat aaaaatggaa aagagttatg 58020
ttattgttat ataacaatag atgatcatta cttggttgat gtggaaacta taggagttat 58080
agtcaataga tctggaaaat gtctgttagt aaataaccat ctaggtatag gtatcgttaa 58140
agataaacgt ataagcgata gttttggaga tgtatgtatg gatacaatat ttgacttttc 58200
tgaagcacga gagttatttt cattaactaa tgatgataac aggaatatag catgggacac 58260
tgataaacta gacgatgata cagatatatg gactcccgtc acagaagatg attacaaatt 58320
tctttctaga ctagtattgt atgcaaaatc tcaatcggat actgtattcg actattatgt 58380
tcttactggt gatacggaac cacccactgt attcattttc aaggtaacta gattttactt 58440
taatatgccg aaataaaaaa tttttgtata atatctagag gtagaggtat tgtttagata 58500
aatacaaata acatagatac atcgcatact tagcattttt ataaatatac ataagacata 58560
cactttatac attttttttg taaaaatact cataaaaaaa tttataaaaa ttatggcaca 58620
accatatctt gtataggtag tttagttcgt cgagtgaacc tataaacaga taatagacaa 58680
cacgtaataa taataatgcc tactaataca agcataatac cgggagatgg gatatatgac 58740
gttgtagtgt ttgggttttc tgaacgttga tagtctacta atactacatg ctgacatcta 58800
atgcctgtat aaccatgaga gcatctacaa tacataccgt caatatctct agcgtggata 58860
cagtcaccgt gtaaacaata tccatctccc tctggaccgc ataatctgat agctggaata 58920
tctgttgtag cgtttgtaat ttctggcgat gtcgtttcga tagcgttacc actatcggcg 58980
aatgatctga ttatcatagc agcgaacaac aacatcagat atttcatcga catttttgat 59040
ggattttgtg tttatgctgt ttctcagtgt gtgtttatga caagattggg aattttatat 59100
tattaattca gtaatataaa ctaataatat attgttaatt gtgtaaataa tataaaaata 59160
acaatacaat attgaatgtg ttgctgttaa aaatgatcat aaacacggag tttattttat 59220
atgtctcgca taaacattac taaaaaaata tattgttctg tttttctttc acatctttaa 59280
ttatgaaaaa gtaaatcatt atgagatgga cgagattgta cgcatcgttc gcgacagtat 59340
gtggtacata cctaacgtat ttatggacga cggtaagaat gaaggtcacg tttctgtcaa 59400
caatgtctgt catatgtatt tcacgttctt tgatgtggat acatcgtctc atctgtttaa 59460
gctagttatt aaacactgcg atctgaataa acgaggtaac tctccattac attgctatac 59520
gatgaataca cgatttaatc catctgtatt aaagatattg ttacaccacg gcatgcgtaa 59580
ctttgatagc aaggatgaaa aaggacacca ctatcaatcg ataacaagat ctttgatata 59640
ctaacggaca ccattgatga ctttagtaaa tcatccgatc tattgctgtg ttatcttaga 59700
tataaattca atgggagctt aaactattac gttctgtaca aaggatccga cgaggatgaa 59760
ctcacttctc ttcattacta ctgtaaacac atatccacgt tctacaaaag caattattac 59820
aagttaagtc acactaagat gcgagccgag aagcgattca tctacgcgat aatagattat 59880
ggagcaaaca ttaacgcggt tacacactta ccttcaacag tataccaaac atagtcctcg 59940
tgtggtgtat gctcttttat ctcgaggagc cgatacgagg atacgtaata atcttgattg 60000
tacacccatc atggaacgat tgtgcaacag gtcatattct cataatgtta ctcaattggc 60060
acgaacaaaa ggaagaagga caacatctac tttatctatt cataaaacat aatcaaggat 60120
acactctcaa tatactacgg tatctactag ataggttcga cattcagaaa gacgaatact 60180
ataataccgc ctttcaaaat tgtaacaaca atgttgcctc atacatcgga tacgacatca 60240
accttccgac taaagacggt attcgacttg gtgtttgaaa acagaaacat catatacaag 60300
gcggatgttg tgaatgacat catccaccac agactgaaag tatctctacc tatgattaaa 60360
tcgttgttct acaagatgtc tctccctacg acgattacta cgtaaagaag ataatagcct 60420
actgcctatt aagggacgag tcattcgcgg aactacatag taaattctgt ttaaacgagg 60480
actataaaag tgtatttatg aaaaatatat cattcgataa gatagattcc atcatcgtga 60540
cataagtcgc cttaaagaga ttcgaatctc cgacaccgac ctgtatacgg tatcacagct 60600
atcttaaagc catacattca gacagtcaca tttcatttcc catgtacgac gatctcatag 60660
aacagtgcca tctatcgatg gagcgtaaaa gtaaactcgt cgacaaagca ctcaataaat 60720
tagagtctac catcggtcaa tctagactat cgtatttgcc tccggaaatt atgcgcaata 60780
tcatctaaac agtatgttgt acgaaaagaa ccattacaaa tattatccat gatagaaaga 60840
aaatatctat atgattggag aagtaggaaa caggaacaag acgacgatta ctacattatt 60900
aaatcatgaa gtccgtatta tactcgtata tattgtttct ctcatgtata ataataaacg 60960
gaagagatat agcaccgcat gcaccatccg atggaaagtg taaagacaac gaatacaaac 61020
gccataattt gtgtccggga acatacgctt ccagattatg cgatagcaag actaacacac 61080
aatgtacgcc gtgtggttcg ggtaccttca catctcgcaa taatcattta cccgcttgtc 61140
taagttgtaa cggaagacgc gaccgtgtaa cacgactcac aatagaatct gtgaatgctc 61200
tcccggatat tattgtcttc tcaaaggatc atccggatgc aaggcatgtg tttcccaaac 61260
aaaatgtgga ataggatacg gagtatccgg agacgtcatc tgttctccgt gtggtctcgg 61320
aacatattct cacaccgtct cttccgcaga taaatgcgaa cccgtaccca gtaatacctt 61380
taactatatc gatgtggaaa ttaatctgta tccagttaac gaccactacc ggtctcagcg 61440
aatccatctc aacgtcggaa ctaactatta ctatgaatca taaagactgt aatcccgtat 61500
ttcgtgagga atacttctcc gtccttaata aggtagcaac ttcaggtttc tttacaggag 61560
aaaggtgtgc actctgaatt tcgagattaa atgcaataac aaaaattttt cctccaaaca 61620
gttaacgaaa gcaaagaatg atgacggtat catgccgcat tcggagactg tctatctagc 61680
gtcgacatct atatactata tagtaatacc aatactcaag actacgaaac tgatacaatc 61740
tcttatcatg tgggtaatgt tctcgatgtc gatagccata tgcccggtag ttgcgatata 61800
cataaactga tcactaattc caaacccacc cgctttttat agtaagtttt tcacccataa 61860
ataataaata caataattaa tttctcgtaa aagtagaaaa tatattctaa tttattgcac 61920
ggtaaggaag tagaatcata aagaacagta ctcaatcaat agcaatcatg aaacaatata 61980
tcgtcctggc atgcatgtgc ctgccagtct tcagcaatca tcctcatcct cctcctcgtg 62040
tacggaagaa gaaaacaaac atcatatggg aatcgatgtt attatcaaag tcacaaagca 62100
agaccaaaca ccgaccaatg ataagatttg ccaatccgta acggaaatta cagagtccga 62160
gtcagatcca gatcccgagg tggaatcaga agatgattcc acatcagtcg aggatgtaga 62220
tcctcctacc acttattact ccatcatcgg tggaggtctg agaatgaact ttggattcac 62280
caaatgtcct cagattaaat ccatctcaga atccgctgat ggaaacacag tgaatgctag 62340
attgtccagc gtgtccccag gacaaggtaa ggactctccc gcgatcactc atgaagaagc 62400
tctggctatg atcaaagact gtgaggtgtc tatcgacatc agatgtagcg aagaagagaa 62460
agacagcgac atcaagaccc atccagtact cgggtctaac atctctcata agaaagtgag 62520
ttacgaagat atcatcggtt caacgatcgt cgatacaaaa tgtgtcaaga atctagagtt 62580
tagcgttcgt atcggagaca tgtgcaagga atcatctgaa cttgaggtca aggatggatt 62640
taagtatgtc gacggatcgg catctgaagg tgcaaccgat gatacttcac tcatcgattc 62700
aacaaaactc aaagcgtgtg tctgaatcga taactctatt catctgaaat tggatgagta 62760
gggttaatcg aacgattcag gcacaccacg aattaaaaaa gtgtaccgga cactatattc 62820
cggtttgcaa aacaaaaatg ttcttaacta cattcacaaa aagttacctc tcgcgacttc 62880
ttctttttct gtctcaatag tgtgatacga ttatgacact attcctattc ctattcctat 62940
ttcctttcag ggtatcacaa aaatattaaa cctctttctg atggtctcat aaaaaaagtt 63000
ttacaaaaat atttttattc tctttctctc tttgatggtc tcataaaaaa agttttacaa 63060
aaatattttt attctctttc tctctttgat ggtctcataa aaaaagtttt acaaaaatat 63120
ttttattctc tttctctctt tgatggtctc ataaaaaaag ttttacaaaa atatttttat 63180
tctctttctc tctttgatgg tctcataaaa aaagttttac aaaaatattt ttattctctt 63240
tctctctttg atggtctcat aaaaaaagtt ttacaaaaat atttttattc tctttctctc 63300
tttgatggtc tcataaaaaa agttttacaa aaatattttt attctctttc tctctttgat 63360
ggtctcataa aaaaagtttt acaaaaatat ttttattctc tttctctctt tgatggtctc 63420
ataaaaaata ttaaacctct ttctgatggt gtcactaaaa tatttttatt ctcattctca 63480
ttttctcttt ctctcttcaa tggagtcata aaatattttt attctctttc tctcttcgat 63540
ggtctcacaa aaatattaaa cctctttctg atggtgtcac taaaatattt ttattctcat 63600
tctcattttc tctttctctc ttcaatggag tcataaaata tttttattct ctttctctct 63660
tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct 63720
ctttctctct tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa 63780
agttttatct ctttctctct tcgatggtct cacaaaaata ttaaacctct ttctgatgga 63840
gtcgtaaaaa agttttatct ctttctctct tcgatggtct cacaaaaata ttaaacctct 63900
ttctgatgga gtcgtaaaaa agttttatct ctttctctct tcgatggtct cacaaaaata 63960
ttaaacctct ttctgatgga gtcgtaaaaa agttttatct ctttctctct tcgatggtct 64020
cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct ctttctctct 64080
tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct 64140
ctttctctct tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa 64200
agttttatct ctttctctct tcgatggtct cacaaaaata ttaaacctct ttctgatgga 64260
gtcgtaaaaa agttttatct ctttctctct tcgatggtct cacaaaaata ttaaacctct 64320
ttctgatgga gtcgtaaaaa agttttatct ctttctctct tcgatggtct cacaaaaata 64380
ttaaacctct ttctgatgga gtcgtaaaaa agttttatct ctttctctct tcgatggtct 64440
cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct ctttctctct 64500
tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct 64560
ctttctctct tcgatggtct cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa 64620
agttttatct ctttctctct tcgatggtct cacaaaaata ttaaacctct ttctgatgga 64680
gtcgtaaaaa agttttatct ctttctctct tcgatggtct cacaaaaata ttaaacctct 64740
ttctgatgga gtcgtaaaaa agttttatct ctttctctct tcgatggtct cacaaaaata 64800
ttaaacctct ttctgatgga gtcgtaaaaa agttttatct ctttctctct tcgatggtct 64860
cacaaaaata ttaaacctct ttctgatgga gtcgtaaaaa agttttatct ctttctctct 64920
tcgatggtct cactaaaata ttttttattc tctttctgat gcatcaacta tttcttaaac 64980
aataacgtcc aacaacatat actcgtcgag cttatcaaca tcccctatgc ccatctaggt 65040
taccagacaa ttgtatatca taaaataatg tttataattt acacgttaaa atcatataat 65100
aaaacgtaga tcgtataata ttttttggta tataaatgat ctagtaaaat ccatgtaggg 65160
gatactgctc acattttttc tttggtacaa aatttcacac aagtttttat acagacaaat 65220
tcttgtccat atattttaaa acattgactt ttgtactaag aaaaatatct agatcaacta 65280
tctctttctc tttctctctt cgatggtctc acaaaaatat taaacctctt tctgatggag 65340
tcgtaaaaaa gttttatctc tttctctctt cgatggtctc acaaaaatat taaacctctt 65400
tctgatggag tcgtaaaaaa gttttatctc tttctctctt cgatggtctc acaaaaatat 65460
taaacctctt tctgatggag tcgtaaaaaa gttttatctc tttctctctt cgatggtctc 65520
acaaaaatat taaacctctt tctgatggag tcgtaaaaaa gttttatctc tttctctctt 65580
cgatggtctc acaaaaatat taaacctctt tctgatggag tcgtaaaaaa gttttatctc 65640
tttctctctt cgatggtctc acaaaaatat taaacctctt tctgatggag tcgtaaaaaa 65700
gttttatctc tttctccttc gatggtctca caaaaatatt aaacctcttt ctgatggagt 65760
cgtaaaaaag ttttatctct ttctctcttc gatggtctca caaaaatatt aaacctcttt 65820
ctgatggagt cgtaaaaaag ttttatctct ttctctcttc gatggtctca caaaaatatt 65880
aaacctcttt ctgatggagt cgtaaaaaag ttttatctct ttctccttcg atggtctcac 65940
aaaaatatta aacctctttc tgatggagtc gtaaaaaagt tttatctctt tctccttcga 66000
tggtctcaca aaaatattaa acctctttct gatggagtcg taaaaaagtt ttatctcttt 66060
ctctcttcga tggtctcaca aaaatattaa acctctttct gatggagtcg taaaaaagtt 66120
ttatctcttt ctctcttcga tggtctcaca aaaatattaa acctctttct gatggtctct 66180
ataaagcgat cgatctttct tacactctag agtttcctac agtcatgggt cacacatttt 66240
tttctagaca ctaaataaaa tatttaaaat ataatattaa tgtactaaaa cttatatatt 66300
attaatttat ctaactaaag ttagtaaatt atatatataa ttttataatt aatttaattt 66360
tactaatttt atttagtgtc tagaaaaaaa 66390
Claims (42)
1.一种产生痘病毒载体或重组痘病毒载体的方法，包括：
将一个或多个DNA片段转染入宿主细胞，其中所述一个或多个DNA片段包含想要的痘病毒的完整基因组DNA序列，使得所述痘病毒在宿主细胞中重构。
2.根据权利要求1所述的方法，其中将两个或更多个DNA片段共转染入宿主细胞，每个DNA片段包含痘病毒基因组的部分序列，使得所述两个或更多个DNA片段通过同源重组组装，且在所述宿主细胞中重构时包含所述痘病毒基因组的全长序列。
3.根据权利要求1或权利要求2所述的方法，进一步包括在转染所述一个或多个DNA片段之前，期间，或之后用辅助病毒感染所述宿主细胞以启动所述一个或多个DNA片段的转录。
4.根据权利要求3所述的方法，其中所述辅助病毒是禽痘病毒(FPV)，羊纤维瘤病毒，痘苗病毒，或牛痘病毒。
5.根据权利要求1-4中任一项所述的方法，其中所述一个或多个DNA片段在转染之前被环化，或以环状形式转染入所述宿主细胞。
6.根据权利要求5所述的方法，其中将所述一个或多个DNA片段克隆至质粒或细菌人工染色体(BAC)载体。
7.根据权利要求1-4中任一项所述的方法，其中所述一个或多个DNA片段在共转染之前被线性化，或以线性化形式转染入所述宿主细胞。
8.根据权利要求1-7中任一项所述的方法，其中所述一个或多个DNA片段是天然衍生的，化学合成的，或天然衍生的和化学合成的DNA片段的组合。
9.根据权利要求1-8中任一项所述的方法，其中所述痘病毒基因组序列包含被修饰的痘苗安卡拉(MVA)登录号#U94848或#AY603355的序列。
10.根据权利要求1-9中任一项所述的方法，其中两个相邻DNA片段具有重叠序列以有助于同源重组。
11.根据权利要求10所述的方法，其中所述重叠序列的长度为约100bp至约5000bp。
12.根据权利要求1-11中任一项所述的方法，其中所述一个或多个DNA片段还包含反向末端重复(ITR)区。
13.根据权利要求1-12中任一项所述的方法，其中所述一个或多个DNA片段还包含痘病毒末端发夹环(HL)序列，痘病毒基因组解析(CR)序列，或两者，其中所述HL或所述CR序列作为单链或双链DNA序列以正义或反义方向添加至DNA片段的一端或两端。
14.根据权利要求13所述的方法，其中所述一个或多个DNA片段进一步包含一个或多个HL序列和一个或多个CR序列。
15.根据权利要求14所述的方法，其中每个HL序列在所述HL序列的两端的侧翼为两个CR序列。
16.根据权利要求13-15中任一项所述的方法，其中仅所述一个或多个DNA片段的子集包含所述HL或CR序列。
17.根据权利要求1-16中任一项所述的方法，其中所述一个或多个DNA片段进一步包含编码一个或多个抗原，亚单位，或其片段的一个或多个DNA序列，或其他异源DNA序列。
18.根据权利要求17所述的方法，其中两个或更多个DNA片段包含相同抗原，亚单位或其片段的DNA序列或相同异源DNA序列。
19.根据权利要求17所述的方法，其中两个或更多个DNA片段包含不同抗原，亚单位，或其片段的DNA序列或其他异源DNA序列。
20.根据权利要求17-19中任一项所述的方法，其中所述抗原，亚单位，或其片段的DNA序列或其他异源DNA序列被密码子优化以在宿主细胞中表达。
21.根据权利要求17-20中任一项所述的方法，其中所述一个或多个DNA片段进一步包含位于所述抗原，亚单位，或其片段的DNA序列或其他异源DNA序列上游的病毒启动子，位于所述抗原，亚单位，或其片段的DNA序列或其他异源DNA序列下游的转录终止信号，或两者。
22.根据权利要求17-21中任一项所述的方法，其中编码所述抗原，亚单位，或其片段的DNA序列或其他异源DNA序列被插入一个或多个痘病毒插入位点或基因间区域中。
23.一种表达系统，包括：
(i)包含想要的痘病毒的整个基因组的单个DNA片段，或各自包含想要的痘病毒基因组的部分序列的两个或更多个DNA片段，使得当在共转染后在宿主细胞中表达时，所述两个或更多个DNA片段顺序组装并包含痘病毒基因组的全长序列且能够重构想要的重组痘病毒，和
(ii)编码一个或多个抗原，亚单位，或其片段的一个或多个DNA序列或其他异源DNA序列被插入痘病毒的一个或多个插入位点中，其中所述抗原或其亚单位或其他异源DNA序列在所述一个或多个痘病毒DNA片段转染和所述痘病毒重构后在宿主细胞中表达。
24.根据权利要求23所述的表达系统，其中所述一个或多个DNA片段在转染之前被环化，或以环状形式转染入所述宿主细胞。
25.根据权利要求24所述的表达系统，其中将所述一个或多个DNA片段克隆至质粒或BAC载体。
26.根据权利要求23所述的表达系统，其中所述一个或多个DNA片段在转染之前被线性化，或以线性化形式转染入所述宿主细胞。
27.根据权利要求23-26中任一项所述的表达系统，其中所述一个或多个DNA片段是天然衍生的，化学合成的，或天然衍生的和化学合成的DNA片段的组合。
28.根据权利要求23-27中任一项所述的表达系统，其中所述痘病毒的基因组序列包含MVA登录号#U94848或#AY603355的序列。
29.根据权利要求23-28中任一项所述的表达系统，其中两个相邻DNA片段具有重叠序列以有助于同源重组。
30.根据权利要求29所述的表达系统，其中所述重叠序列的长度为约100bp至约5000bp。
31.根据权利要求23-30中任一项所述的表达系统，其中所述一个或多个DNA片段还包含反向末端重复(ITR)区。
32.根据权利要求23-31中任一项所述的表达系统，其中所述一个或多个DNA片段还包含痘病毒末端发夹环(HL)序列，痘病毒基因组解析(CR)序列，或两者，其中所述HL或所述CR序列作为单链或双链DNA序列以正义或反义方向添加至DNA片段的一端或两端。
33.根据权利要求32所述的表达系统，其中所述一个或多个DNA片段进一步包含一个或多个HL序列和一个或多个CR序列。
34.根据权利要求33所述的表达系统，其中每个HL序列在所述HL序列的两端的侧翼为两个CR序列。
35.根据权利要求32-34中任一项所述的表达系统，其中仅所述一个或多个DNA片段的子集包含所述HL或CR序列。
36.根据权利要求23-35中任一项所述的表达系统，其中所述一个或多个DNA片段进一步包含编码所述抗原，亚单位，或其片段的DNA序列或其他异源DNA序列上游的病毒启动子，编码所述抗原，亚单位，或其片段的DNA序列或其他异源DNA序列下游的转录终止信号，或两者。
37.根据权利要求23-36中任一项的表达系统，其中编码一个或多个抗原，亚单位，或其片段的DNA序列或其他异源DNA序列被插入一个或多个痘病毒插入位点中。
38.一种用于预防或治疗癌症或病毒感染的疫苗组合物，包括：
(i)包含想要的痘病毒的整个基因组的单个DNA片段，或各自包含想要的痘病毒基因组的部分序列的两个或更多个DNA片段，使得当在共转染后转移入宿主细胞时，所述两个或更多个DNA片段顺序组装并包含痘病毒基因组的全长序列，和
(ii)编码一个或多个抗原，亚单位，或其片段的一个或多个DNA序列或其他异源DNA序列被插入痘病毒的一个或多个插入位点中，其中所述抗原，亚单位或其片段或其他异源DNA序列在所述一个或多个痘病毒DNA片段转染后在宿主细胞中表达。
39.根据权利要求38所述的疫苗组合物，其中将所述抗原，亚单位或其片段或其他异源DNA序列插入一个或多个痘病毒插入位点中。
40.如权利要求38或权利要求39所述的疫苗组合物，还包含药学上可接受的载体，佐剂，添加剂，或其组合。
41.一种预防或治疗受试者癌症或病毒感染的方法，包括向所述受试者施用预防或治疗有效量的疫苗组合物，其中所述疫苗包括：
(i)包含想要的痘病毒的整个基因组的单个DNA片段，或各自包含想要的痘病毒基因组的部分序列的两个或更多个DNA片段，使得当在共转染后转移入宿主细胞时，所述两个或更多个DNA片段顺序组装并包含痘病毒基因组的全长序列，和
(ii)编码一个或多个抗原，亚单位，或其片段的一个或多个DNA序列或其他异源DNA序列被插入痘病毒的一个或多个插入位点中，其中所述抗原，亚单位或其片段或其他异源DNA序列在所述一个或多个痘病毒DNA片段转染后在宿主细胞中表达。
42.根据权利要求41所述的方法，其中将所述抗原，亚单位，或其片段或其他异源DNA序列插入一个或多个痘病毒插入位点中。
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| PCT/US2021/016247 WO2021158565A2 (en) | 2020-02-03 | 2021-02-02 | Poxvirus-based vectors produced by natural or synthetic dna and uses thereof |
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| EP4100514A2 (en) | 2022-12-14 |
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