CN116323917A - 人原始生殖细胞/人原始生殖细胞样细胞的维持扩增方法 - Google Patents
人原始生殖细胞/人原始生殖细胞样细胞的维持扩增方法 Download PDFInfo
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- C12N2501/20—Cytokines; Chemokines
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- C12N2501/235—Leukemia inhibitory factor [LIF]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C12N2533/52—Fibronectin; Laminin
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063066914P | 2020-08-18 | 2020-08-18 | |
| US63/066914 | 2020-08-18 | ||
| US202063067776P | 2020-08-19 | 2020-08-19 | |
| US63/067776 | 2020-08-19 | ||
| PCT/JP2021/030701 WO2022039279A1 (ja) | 2020-08-18 | 2021-08-17 | ヒト始原生殖細胞/ヒト始原生殖細胞様細胞の維持増幅方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116323917A true CN116323917A (zh) | 2023-06-23 |
Family
ID=80323037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180050606.4A Pending CN116323917A (zh) | 2020-08-18 | 2021-08-17 | 人原始生殖细胞/人原始生殖细胞样细胞的维持扩增方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240271088A1 (https=) |
| EP (1) | EP4202041A4 (https=) |
| JP (1) | JPWO2022039279A1 (https=) |
| CN (1) | CN116323917A (https=) |
| WO (1) | WO2022039279A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4563697A4 (en) | 2022-07-25 | 2025-11-12 | Univ Kyoto | IN VITRO CULTURE METHOD FOR INDUCING OVARIAN FOLLICLES FROM PRIMATE FETAL OVARIAN CELLS |
| CN121712884A (zh) * | 2023-08-21 | 2026-03-20 | 国立大学法人京都大学 | 卵原细胞或前精原细胞的制造方法 |
Citations (6)
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| US20160010056A1 (en) * | 2013-03-01 | 2016-01-14 | Kyoto University | Method of inducing differentiation from pluripotent stem cells to germ cells |
| US20180187147A1 (en) * | 2015-06-29 | 2018-07-05 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into germ cells |
| CN108368483A (zh) * | 2015-09-17 | 2018-08-03 | 学校法人东京农业大学 | 将原始生殖细胞分化为功能上成熟的卵母细胞的培养方法 |
| CN108884436A (zh) * | 2015-08-13 | 2018-11-23 | 北昊干细胞与再生医学研究院有限公司 | 诱导的扩展的多潜能干细胞、制备及使用方法 |
| CN110004112A (zh) * | 2019-04-18 | 2019-07-12 | 宁夏医科大学 | 一种诱导人多能干细胞体外分化为停滞在减数分裂ii期的卵母细胞的方法 |
| US20200248138A1 (en) * | 2017-06-07 | 2020-08-06 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into germline stem cell-like cells |
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| CA2277278A1 (en) | 1997-01-10 | 1998-07-16 | Life Technologies, Inc. | Embryonic stem cell serum replacement |
| US6331406B1 (en) * | 1997-03-31 | 2001-12-18 | The John Hopkins University School Of Medicine | Human enbryonic germ cell and methods of use |
| US9453219B2 (en) | 2003-05-15 | 2016-09-27 | Mello Biotech Taiwan Co., Ltd. | Cosmetic designs and products using intronic RNA |
| US8048999B2 (en) | 2005-12-13 | 2011-11-01 | Kyoto University | Nuclear reprogramming factor |
| JP5813321B2 (ja) | 2007-03-23 | 2015-11-17 | ウィスコンシン アラムニ リサーチ ファンデーション | 体細胞の再プログラム化 |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| ES2799897T3 (es) | 2007-08-31 | 2020-12-22 | Whitehead Inst Biomedical Res | Estimulación de la vía wnt en la reprogramación de células somáticas |
| KR101564044B1 (ko) | 2007-10-31 | 2015-10-28 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 핵초기화 방법 |
| JP5558097B2 (ja) | 2007-12-10 | 2014-07-23 | 国立大学法人京都大学 | 効率的な核初期化方法 |
| WO2009079007A1 (en) | 2007-12-17 | 2009-06-25 | Gliamed, Inc. | Stem-like cells and method for reprogramming adult mammalian somatic cells |
| WO2009091659A2 (en) | 2008-01-16 | 2009-07-23 | Shi-Lung Lin | Generation of tumor-free embryonic stem-like pluripotent cells using inducible recombinant rna agents |
| US20100330677A1 (en) | 2008-02-11 | 2010-12-30 | Cambridge Enterprise Limited | Improved Reprogramming of Mammalian Cells, and Cells Obtained |
| EP2090649A1 (en) | 2008-02-13 | 2009-08-19 | Fondazione Telethon | Method for reprogramming differentiated cells |
| WO2009102983A2 (en) | 2008-02-15 | 2009-08-20 | President And Fellows Of Harvard College | Efficient induction of pluripotent stem cells using small molecule compounds |
| MX2010010165A (es) | 2008-03-17 | 2010-11-25 | Scripps Research Inst | Procedimientos quimicos y geneticos combinados para generacion de celulas madre pluripotentes inducidas. |
| WO2009114949A1 (en) | 2008-03-20 | 2009-09-24 | UNIVERSITé LAVAL | Methods for deprogramming somatic cells and uses thereof |
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| KR20110019727A (ko) | 2008-04-07 | 2011-02-28 | 뉴포텐셜, 인크. | Rna 간섭을 통한 다능 유전자의 유도에 의한 세포 재프로그래밍 |
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| WO2010008054A1 (ja) | 2008-07-16 | 2010-01-21 | ディナベック株式会社 | 染色体非組み込み型ウイルスベクターを用いてリプログラムされた細胞を製造する方法 |
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| WO2019107576A1 (ja) | 2017-11-30 | 2019-06-06 | 国立大学法人京都大学 | 始原生殖細胞/始原生殖細胞様細胞の維持増幅及び分化誘導方法 |
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2021
- 2021-08-17 US US18/042,134 patent/US20240271088A1/en active Pending
- 2021-08-17 CN CN202180050606.4A patent/CN116323917A/zh active Pending
- 2021-08-17 WO PCT/JP2021/030701 patent/WO2022039279A1/ja not_active Ceased
- 2021-08-17 JP JP2022544032A patent/JPWO2022039279A1/ja active Pending
- 2021-08-17 EP EP21858422.5A patent/EP4202041A4/en not_active Withdrawn
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160010056A1 (en) * | 2013-03-01 | 2016-01-14 | Kyoto University | Method of inducing differentiation from pluripotent stem cells to germ cells |
| US20180187147A1 (en) * | 2015-06-29 | 2018-07-05 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into germ cells |
| CN108884436A (zh) * | 2015-08-13 | 2018-11-23 | 北昊干细胞与再生医学研究院有限公司 | 诱导的扩展的多潜能干细胞、制备及使用方法 |
| CN108368483A (zh) * | 2015-09-17 | 2018-08-03 | 学校法人东京农业大学 | 将原始生殖细胞分化为功能上成熟的卵母细胞的培养方法 |
| US20200248138A1 (en) * | 2017-06-07 | 2020-08-06 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into germline stem cell-like cells |
| CN110004112A (zh) * | 2019-04-18 | 2019-07-12 | 宁夏医科大学 | 一种诱导人多能干细胞体外分化为停滞在减数分裂ii期的卵母细胞的方法 |
Non-Patent Citations (3)
| Title |
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| JOANNA J. GELL ET AL.: "An Extended Culture System that Supports Human Primordial Germ Cell-like Cell Survival and Initiation of DNA Methylation Erasure", 《STEM CELL REPORTS》, vol. 14, 10 March 2020 (2020-03-10), pages 434 * |
| YAMASHIRO ET AL.: "Generation of human oogonia from induced pluripotent stem cells in culture", 《NATURE PROTOCOLS》, vol. 15, 30 April 2020 (2020-04-30), pages 1574 * |
| YOSHITAKE SAKAI ET AL.: "Induction of the Germ-Cell Fate from Pluripotent Stem Cells in Cynomolgus Monkeys", 《BIOL REPROD》, vol. 102, no. 3, 31 December 2019 (2019-12-31), pages 3 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4202041A1 (en) | 2023-06-28 |
| JPWO2022039279A1 (https=) | 2022-02-24 |
| WO2022039279A1 (ja) | 2022-02-24 |
| EP4202041A4 (en) | 2024-10-16 |
| US20240271088A1 (en) | 2024-08-15 |
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